Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	TBX15 FOXO1 TFEB ZNF18 HNF1B OTX1 KMT2D USF3 SALL3 NKX2-4 DACH1 ZNF317 ZNF236 FOXJ3 MEIS1 TBX2	5.78e-07	1412	54	16	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	TBX15 FOXO1 TFEB ZNF18 HNF1B OTX1 IKZF2 SALL3 NKX2-4 DACH1 ZNF317 ZNF236 FOXJ3 MEIS1 TBX2	6.56e-07	1244	54	15	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	TBX15 FOXO1 TFEB ZNF18 HNF1B OTX1 IKZF2 SALL3 NKX2-4 DACH1 ZNF317 ZNF236 FOXJ3 MEIS1 TBX2	8.61e-07	1271	54	15	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	TBX15 FOXO1 TFEB ZNF18 HNF1B OTX1 USF3 IKZF2 SALL3 NKX2-4 DACH1 ZNF317 ZNF236 FOXJ3 MEIS1 TBX2	8.96e-07	1459	54	16	GO:0000977
GeneOntologyMolecularFunction	transcription coactivator activity	BCL9L KMT2D TCF20 MAML1 MED14 MED12L BCL9	1.66e-05	303	54	7	GO:0003713
GeneOntologyMolecularFunction	structural constituent of tooth enamel	AMELX AMELY	1.07e-04	6	54	2	GO:0030345
GeneOntologyMolecularFunction	transcription coregulator activity	BCL9L KMT2D MLIP TCF20 MAML1 MED14 MED12L BCL9	1.25e-04	562	54	8	GO:0003712
GeneOntologyMolecularFunction	hydroxyapatite binding	AMELX AMELY	1.99e-04	8	54	2	GO:0046848
GeneOntologyMolecularFunction	beta-catenin binding	FOXO1 BCL9L MED12L BCL9	3.11e-04	120	54	4	GO:0008013
GeneOntologyMolecularFunction	sodium ion binding	AMELX AMELY	6.40e-04	14	54	2	GO:0031402
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXO1 TFEB OTX1 KMT2D USF3 FOXJ3 MEIS1	7.43e-04	560	54	7	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	FOXO1 TFEB OTX1 KMT2D USF3 FOXJ3 MEIS1	7.91e-04	566	54	7	GO:0001216
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring compression resistance	AMELX AMELY	1.75e-03	23	54	2	GO:0030021
GeneOntologyMolecularFunction	alkali metal ion binding	AMELX AMELY	2.24e-03	26	54	2	GO:0031420
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	FOXO1 TFEB BCL9L HNF1B OTX1 KMT2D USF3 IKZF2 OGT MLIP TCF20 MAML1 MED14 MED12L BCL9 FOXJ3 MEIS1 TBX2	6.93e-09	1390	54	18	GO:0045944
GeneOntologyBiologicalProcess	stem cell population maintenance	FOXO1 BCL9L HNF1B OGT MED14 BCL9	3.52e-05	237	54	6	GO:0019827
GeneOntologyBiologicalProcess	maintenance of cell number	FOXO1 BCL9L HNF1B OGT MED14 BCL9	3.95e-05	242	54	6	GO:0098727
GeneOntologyCellularComponent	chromatin	TBX15 FOXO1 TFEB TRIM33 TRIM66 HNF1B OTX1 OGT NKX2-4 CECR2 FOXJ3 ZC3H6 MEIS1 TBX2	1.31e-05	1480	53	14	GO:0000785
GeneOntologyCellularComponent	transcription regulator complex	TBX15 TFEB BCL9L HNF1B MED14 DACH1 BCL9 MEIS1 TBX2	1.70e-05	596	53	9	GO:0005667
GeneOntologyCellularComponent	beta-catenin-TCF complex	BCL9L BCL9	4.83e-04	13	53	2	GO:1990907
MousePheno	short Tomes' process	AMELX AMELY	1.01e-05	2	45	2	MP:0030513
MousePheno	abnormal Tomes' process morphology	AMELX AMELY	3.03e-05	3	45	2	MP:0030512
MousePheno	abnormal proamniotic cavity morphology	TRIM33 HNF1B TLN1	6.02e-05	24	45	3	MP:0011197
MousePheno	large mandible	AMELX AMELY	6.05e-05	4	45	2	MP:0030050
MousePheno	enamel pits	AMELX AMELY	1.01e-04	5	45	2	MP:0030460
MousePheno	short upper incisors	AMELX AMELY	1.51e-04	6	45	2	MP:0030090
MousePheno	small upper incisors	AMELX AMELY	2.11e-04	7	45	2	MP:0030081
MousePheno	short lower incisors	AMELX AMELY	2.11e-04	7	45	2	MP:0030089
MousePheno	absent ectoplacental cavity	HNF1B TLN1	2.80e-04	8	45	2	MP:0011207
MousePheno	abnormal enamel rod pattern	AMELX AMELY	2.80e-04	8	45	2	MP:0002649
Domain	CCDC74_C	CCDC74B CCDC74A	7.90e-06	2	53	2	PF14917
Domain	BCL9_beta-catenin-bd_dom	BCL9L BCL9	7.90e-06	2	53	2	IPR024670
Domain	-	TLN1 TLN2	7.90e-06	2	53	2	1.20.1420.10
Domain	BCL9	BCL9L BCL9	7.90e-06	2	53	2	PF11502
Domain	CCDC74	CCDC74B CCDC74A	7.90e-06	2	53	2	IPR033226
Domain	Talin_middle	TLN1 TLN2	7.90e-06	2	53	2	PF09141
Domain	Amelogenin	AMELX AMELY	7.90e-06	2	53	2	SM00818
Domain	Amelogenin	AMELX AMELY	7.90e-06	2	53	2	PF02948
Domain	VBS	TLN1 TLN2	7.90e-06	2	53	2	PF08913
Domain	CCDC74_C	CCDC74B CCDC74A	7.90e-06	2	53	2	IPR029422
Domain	Amelogenin	AMELX AMELY	7.90e-06	2	53	2	IPR004116
Domain	Vinculin-bd_dom	TLN1 TLN2	7.90e-06	2	53	2	IPR015009
Domain	Talin_cent	TLN1 TLN2	7.90e-06	2	53	2	IPR015224
Domain	Bcl-9	BCL9L BCL9	7.90e-06	2	53	2	IPR015668
Domain	Talin-1	TLN1 TLN2	2.37e-05	3	53	2	IPR015710
Domain	I_LWEQ	TLN1 TLN2	4.72e-05	4	53	2	PF01608
Domain	ILWEQ_dom	TLN1 TLN2	4.72e-05	4	53	2	IPR002558
Domain	I_LWEQ	TLN1 TLN2	4.72e-05	4	53	2	PS50945
Domain	ILWEQ	TLN1 TLN2	4.72e-05	4	53	2	SM00307
Domain	FERM_f0	TLN1 TLN2	4.72e-05	4	53	2	IPR032425
Domain	FERM_f0	TLN1 TLN2	4.72e-05	4	53	2	PF16511
Domain	ILWEQ	TLN1 TLN2	4.72e-05	4	53	2	PD011820
Domain	-	TLN1 TLN2	4.72e-05	4	53	2	1.20.1410.10
Domain	PHD	TRIM33 TRIM66 KMT2D TCF20	1.18e-04	89	53	4	SM00249
Domain	Znf_PHD	TRIM33 TRIM66 KMT2D TCF20	1.29e-04	91	53	4	IPR001965
Domain	ZF_PHD_2	TRIM33 TRIM66 KMT2D TCF20	1.52e-04	95	53	4	PS50016
Domain	BROMODOMAIN_1	TRIM33 TRIM66 CECR2	1.57e-04	37	53	3	PS00633
Domain	ZF_PHD_1	TRIM33 TRIM66 KMT2D TCF20	1.58e-04	96	53	4	PS01359
Domain	Vinculin/catenin	TLN1 TLN2	1.64e-04	7	53	2	IPR006077
Domain	Bromodomain	TRIM33 TRIM66 CECR2	1.70e-04	38	53	3	PF00439
Domain	BROMODOMAIN_2	TRIM33 TRIM66 CECR2	2.13e-04	41	53	3	PS50014
Domain	BROMO	TRIM33 TRIM66 CECR2	2.29e-04	42	53	3	SM00297
Domain	Bromodomain	TRIM33 TRIM66 CECR2	2.29e-04	42	53	3	IPR001487
Domain	-	TRIM33 TRIM66 CECR2	2.29e-04	42	53	3	1.20.920.10
Domain	IRS_PTB	TLN1 TLN2	7.03e-04	14	53	2	IPR002404
Domain	IRS	TLN1 TLN2	7.03e-04	14	53	2	PF02174
Domain	Znf_FYVE_PHD	TRIM33 TRIM66 KMT2D TCF20	8.00e-04	147	53	4	IPR011011
Domain	Bbox_C	TRIM33 TRIM66	8.10e-04	15	53	2	IPR003649
Domain	BBC	TRIM33 TRIM66	8.10e-04	15	53	2	SM00502
Domain	TF_T-box	TBX15 TBX2	1.05e-03	17	53	2	IPR001699
Domain	TBOX	TBX15 TBX2	1.05e-03	17	53	2	SM00425
Domain	TF_T-box_CS	TBX15 TBX2	1.05e-03	17	53	2	IPR018186
Domain	-	TBX15 TBX2	1.05e-03	17	53	2	2.60.40.820
Domain	TBOX_3	TBX15 TBX2	1.05e-03	17	53	2	PS50252
Domain	T-box	TBX15 TBX2	1.05e-03	17	53	2	PF00907
Domain	TBOX_1	TBX15 TBX2	1.05e-03	17	53	2	PS01283
Domain	TBOX_2	TBX15 TBX2	1.05e-03	17	53	2	PS01264
Domain	PHD	TRIM33 TRIM66 KMT2D	1.26e-03	75	53	3	PF00628
Domain	Znf_PHD-finger	TRIM33 TRIM66 KMT2D	1.47e-03	79	53	3	IPR019787
Domain	EPHD	KMT2D TCF20	1.76e-03	22	53	2	PS51805
Domain	FERM_CS	TLN1 TLN2	2.10e-03	24	53	2	IPR019747
Domain	FERM_N	TLN1 TLN2	3.94e-03	33	53	2	PF09379
Domain	FERM_N	TLN1 TLN2	3.94e-03	33	53	2	IPR018979
Domain	Homeobox	HNF1B OTX1 NKX2-4 MEIS1	4.35e-03	234	53	4	PF00046
Domain	HOMEOBOX_1	HNF1B OTX1 NKX2-4 MEIS1	4.48e-03	236	53	4	PS00027
Domain	HOX	HNF1B OTX1 NKX2-4 MEIS1	4.55e-03	237	53	4	SM00389
Domain	HOMEOBOX_2	HNF1B OTX1 NKX2-4 MEIS1	4.69e-03	239	53	4	PS50071
Domain	Homeobox_dom	HNF1B OTX1 NKX2-4 MEIS1	4.69e-03	239	53	4	IPR001356
Domain	-	TLN1 IQSEC2 ARHGEF12 TLN2 TNS1	4.93e-03	391	53	5	2.30.29.30
Pathway	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX	BCL9L KMT2D BCL9	4.50e-05	26	38	3	MM14793
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	FOXO1 HNF1B MAML1	1.93e-04	42	38	3	M17541
Pathway	REACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX	BCL9L KMT2D BCL9	1.93e-04	42	38	3	M27272
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY	TLN1 TLN2	2.52e-04	9	38	2	M47725
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	FOXO1 TFEB TRIM33 HNF1B KMT2D TLN1 RANBP9 MAML1 MED14 ARHGEF12 MEIS1 TBX2	2.52e-04	1432	38	12	M509
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TBX15 FOXO1 TFEB ZNF18 OTX1 IKZF2 SALL3 TCF20 NKX2-4 ZNF236 FOXJ3 ZC3H6 ABTB2 MEIS1	1.64e-11	808	54	14	20412781
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	TRIM33 BCL9L IL16 OTX1 SF3B4 TCF20 CECR2 MAML1 DACH1 U2AF2 BCL9	4.77e-11	425	54	11	24999758
Pubmed	A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.	BCL9L AMELX AMELY BCL9	5.13e-09	14	54	4	28174279
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TRIM33 BCL9L KMT2D OGT TCF20 MAML1 MED14 BCL9	8.58e-09	268	54	8	33640491
Pubmed	Interaction network of human early embryonic transcription factors.	TRIM33 BCL9L KMT2D OGT TCF20 MAML1 BCL9 TBX2	6.90e-08	351	54	8	38297188
Pubmed	A census of human transcription factors: function, expression and evolution.	TBX15 FOXO1 TFEB OTX1 KMT2D USF3 NKX2-4 ZNF236 FOXJ3 MEIS1 TBX2	1.24e-07	908	54	11	19274049
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	TRIM33 BCL9L HNF1B KMT2D TCF20 ATXN2 MAML1 BCL9	5.12e-07	457	54	8	32344865
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TRIM33 KMT2D OGT TCF20 ATXN2 TLN1 MAML1 MED14 DACH1 BCL9 FOXJ3	8.52e-07	1103	54	11	34189442
Pubmed	Amelogenin-deficient mice display an amelogenesis imperfecta phenotype.	AMELX AMELY	2.37e-06	2	54	2	11406633
Pubmed	The receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenic pathway is elevated in amelogenin-null mice.	AMELX AMELY	2.37e-06	2	54	2	12851394
Pubmed	Amelogenin, the major protein of tooth enamel: a new phylogenetic marker for ordinal mammal relationships.	AMELX AMELY	2.37e-06	2	54	2	18346915
Pubmed	Amelogenin X impacts age-dependent increase of frequency and number in labial incisor grooves in C57BL/6.	AMELX AMELY	2.37e-06	2	54	2	29337060
Pubmed	Molecular cloning and DNA sequence of rat amelogenin and a comparative analysis of mammalian amelogenin protein sequence divergence.	AMELX AMELY	2.37e-06	2	54	2	8297387
Pubmed	Thermal denaturation of a recombinant mouse amelogenin: circular dichroism and differential scanning calorimetric studies.	AMELX AMELY	2.37e-06	2	54	2	16284958
Pubmed	Human and mouse amelogenin gene loci are on the sex chromosomes.	AMELX AMELY	2.37e-06	2	54	2	2737677
Pubmed	A solution NMR investigation into the early events of amelogenin nanosphere self-assembly initiated with sodium chloride or calcium chloride.	AMELX AMELY	2.37e-06	2	54	2	19086270
Pubmed	Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell.	TLN1 TLN2	2.37e-06	2	54	2	26822056
Pubmed	Molecular structure of the mouse amelogenin genomic DNA.	AMELX AMELY	2.37e-06	2	54	2	8988368
Pubmed	Extracellular rigidity sensing by talin isoform-specific mechanical linkages.	TLN1 TLN2	2.37e-06	2	54	2	26523364
Pubmed	Hierarchical self-assembly of amelogenin and the regulation of biomineralization at the nanoscale.	AMELX AMELY	2.37e-06	2	54	2	21825148
Pubmed	Polypeptides translated from alternatively spliced transcripts of the amelogenin gene, devoid of the exon 6a, b, c region, have specific effects on tooth germ development in culture.	AMELX AMELY	2.37e-06	2	54	2	12489164
Pubmed	Amelogenin: a potential regulator of cementum-associated genes.	AMELX AMELY	2.37e-06	2	54	2	14653387
Pubmed	A synthetic, chemically modified ribozyme eliminates amelogenin, the major translation product in developing mouse enamel in vivo.	AMELX AMELY	2.37e-06	2	54	2	7489712
Pubmed	The leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution.	AMELX AMELY	2.37e-06	2	54	2	25449314
Pubmed	High-yield recombinant bacterial expression of 13 C-, 15 N-labeled, serine-16 phosphorylated, murine amelogenin using a modified third generation genetic code expansion protocol.	AMELX AMELY	2.37e-06	2	54	2	36585836
Pubmed	Isolation and characterization of a mouse amelogenin expressed in Escherichia coli.	AMELX AMELY	2.37e-06	2	54	2	8062146
Pubmed	Transgenic mice that express normal and mutated amelogenins.	AMELX AMELY	2.37e-06	2	54	2	17384027
Pubmed	Alternative splicing of the mouse amelogenin primary RNA transcript.	AMELX AMELY	2.37e-06	2	54	2	7820782
Pubmed	Controlled Osteogenic Differentiation of Mouse Mesenchymal Stem Cells by Tetracycline-Controlled Transcriptional Activation of Amelogenin.	AMELX AMELY	2.37e-06	2	54	2	26709694
Pubmed	Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta.	AMELX AMELY	2.37e-06	2	54	2	7782077
Pubmed	Comparison of body weight and gene expression in amelogenin null and wild-type mice.	AMELX AMELY	2.37e-06	2	54	2	16674684
Pubmed	Enamel ribbons, surface nodules, and octacalcium phosphate in C57BL/6 Amelx-/- mice and Amelx+/- lyonization.	AMELX AMELY	2.37e-06	2	54	2	27896287
Pubmed	Amelogenin-collagen interactions regulate calcium phosphate mineralization in vitro.	AMELX AMELY	2.37e-06	2	54	2	20404336
Pubmed	Maintenance of amelogenin gene expression by transformed epithelial cells of mouse enamel organ.	AMELX AMELY	2.37e-06	2	54	2	1444889
Pubmed	Identification of the functional activity of the [A-4] amelogenin gene splice product in newborn mouse ameloblasts.	AMELX AMELY	2.37e-06	2	54	2	18394981
Pubmed	A solution NMR investigation into the impaired self-assembly properties of two murine amelogenins containing the point mutations T21→I or P41→T.	AMELX AMELY	2.37e-06	2	54	2	23896516
Pubmed	Stage-Specific Role of Amelx Activation in Stepwise Ameloblast Induction from Mouse Induced Pluripotent Stem Cells.	AMELX AMELY	2.37e-06	2	54	2	34281250
Pubmed	The X-Y homologous gene amelogenin maps to the short arms of both the X and Y chromosomes and is highly conserved in primates.	AMELX AMELY	2.37e-06	2	54	2	1427830
Pubmed	Transgene animal model for protein expression and accumulation into forming enamel.	AMELX AMELY	2.37e-06	2	54	2	11063035
Pubmed	Regulation of amelogenin gene expression.	AMELX AMELY	2.37e-06	2	54	2	10200911
Pubmed	Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration.	BCL9L BCL9	2.37e-06	2	54	2	38811552
Pubmed	Truncated amelogenin and LRAP transgenes improve Amelx null mouse enamel.	AMELX AMELY	2.37e-06	2	54	2	26607574
Pubmed	A human X-Y homologous region encodes "amelogenin".	AMELX AMELY	2.37e-06	2	54	2	2004775
Pubmed	Loss of biological control of enamel mineralization in amelogenin-phosphorylation-deficient mice.	AMELX AMELY	2.37e-06	2	54	2	35219810
Pubmed	Of mice and men: anatomy of the amelogenin gene.	AMELX AMELY	2.37e-06	2	54	2	2689082
Pubmed	Altering biomineralization by protein design.	AMELX AMELY	2.37e-06	2	54	2	16707492
Pubmed	Amelogenin supramolecular assembly in nanospheres defined by a complex helix-coil-PPII helix 3D-structure.	AMELX AMELY	2.37e-06	2	54	2	21984897
Pubmed	Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.	BCL9L BCL9	2.37e-06	2	54	2	15371335
Pubmed	The murine amelogenin promoter: developmentally regulated expression in transgenic animals.	AMELX AMELY	2.37e-06	2	54	2	9084642
Pubmed	Cryogenic transmission electron microscopy study of amelogenin self-assembly at different pH.	AMELX AMELY	2.37e-06	2	54	2	21597263
Pubmed	IQ-ArfGEF/BRAG1 is associated with synaptic ribbons in the mouse retina.	IQSEC2 ARHGEF12	2.37e-06	2	54	2	19811534
Pubmed	Characterization of copy number variation in genomic regions containing STR loci using array comparative genomic hybridization.	AMELX AMELY	2.37e-06	2	54	2	23948316
Pubmed	Antisense inhibition of AMEL translation demonstrates supramolecular controls for enamel HAP crystal growth during embryonic mouse molar development.	AMELX AMELY	2.37e-06	2	54	2	8392462
Pubmed	Amelogenins as potential buffers during secretory-stage amelogenesis.	AMELX AMELY	2.37e-06	2	54	2	25535204
Pubmed	An amelogenin mutation leads to disruption of the odontogenic apparatus and aberrant expression of Notch1.	AMELX AMELY	2.37e-06	2	54	2	20923441
Pubmed	Model system for evaluation of alternative splicing: exon skipping.	AMELX AMELY	2.37e-06	2	54	2	11879574
Pubmed	Patchy fur, a mouse coat mutation associated with X-Y nondisjunction, maps to the pseudoautosomal boundary region.	AMELX AMELY	2.37e-06	2	54	2	9878259
Pubmed	Analysis of self-assembly and apatite binding properties of amelogenin proteins lacking the hydrophilic C-terminal.	AMELX AMELY	2.37e-06	2	54	2	11852235
Pubmed	Role of MAML1 and MEIS1 in Esophageal Squamous Cell Carcinoma Depth of Invasion.	MAML1 MEIS1	2.37e-06	2	54	2	28462489
Pubmed	Amelogenin genes and sexual dimorphism of teeth in humans and mice.	AMELX AMELY	2.37e-06	2	54	2	1463023
Pubmed	Translocation of enamel proteins from inner enamel epithelia to odontoblasts during mouse tooth development.	AMELX AMELY	2.37e-06	2	54	2	8179220
Pubmed	Phosphorylation and ionic strength alter the LRAP-HAP interface in the N-terminus.	AMELX AMELY	2.37e-06	2	54	2	23477367
Pubmed	Protein interactions during assembly of the enamel organic extracellular matrix.	AMELX AMELY	2.37e-06	2	54	2	9041053
Pubmed	Highly acidic pH facilitates enamel protein self-assembly, apatite crystal growth and enamel protein interactions in the early enamel matrix.	AMELX AMELY	2.37e-06	2	54	2	36569763
Pubmed	Exon4 amelogenin transcripts in enamel biomineralization.	AMELX AMELY	2.37e-06	2	54	2	25792521
Pubmed	The leucine-rich amelogenin peptide alters the amelogenin null enamel phenotype.	AMELX AMELY	2.37e-06	2	54	2	18701811
Pubmed	Expression of amelogenin in odontoblasts.	AMELX AMELY	2.37e-06	2	54	2	12667550
Pubmed	Spatial- and temporal-restricted pattern for amelogenin gene expression during mouse molar tooth organogenesis.	AMELX AMELY	2.37e-06	2	54	2	3253061
Pubmed	Putative signaling action of amelogenin utilizes the Wnt/beta-catenin pathway.	AMELX AMELY	2.37e-06	2	54	2	19462488
Pubmed	Isolation and characterization of a pseudoautosomal region-specific genetic marker in C57BL/6 mice using genomic representational difference analysis.	AMELX AMELY	2.37e-06	2	54	2	8618899
Pubmed	A mutation in the mouse Amelx tri-tyrosyl domain results in impaired secretion of amelogenin and phenocopies human X-linked amelogenesis imperfecta.	AMELX AMELY	2.37e-06	2	54	2	20067920
Pubmed	Novel LRAP-binding partner revealing the plasminogen activation system as a regulator of cementoblast differentiation and mineral nodule formation in vitro.	AMELX AMELY	2.37e-06	2	54	2	31621902
Pubmed	Reuptake of extracellular amelogenin by dental epithelial cells results in increased levels of amelogenin mRNA through enhanced mRNA stabilization.	AMELX AMELY	2.37e-06	2	54	2	16293627
Pubmed	The design of coiled-coil structures and assemblies.	CCDC74A CCDC168	2.37e-06	2	54	2	15837514
Pubmed	Leucine rich amelogenin peptide alters ameloblast differentiation in vivo.	AMELX AMELY	2.37e-06	2	54	2	23747796
Pubmed	Evolution in tooth developmental biology: of morphology and molecules.	AMELX AMELY	2.37e-06	2	54	2	8769659
Pubmed	Amelogenin promotes odontoblast-like MDPC-23 cell differentiation via activation of ERK1/2 and p38 MAPK.	AMELX AMELY	2.37e-06	2	54	2	21547453
Pubmed	New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.	TLN1 TLN2	2.37e-06	2	54	2	22306379
Pubmed	Alternative splicing of the mouse amelogenin primary RNA transcript contributes to amelogenin heterogeneity.	AMELX AMELY	2.37e-06	2	54	2	1445358
Pubmed	Altered amelogenin self-assembly based on mutations observed in human X-linked amelogenesis imperfecta (AIH1).	AMELX AMELY	2.37e-06	2	54	2	11877393
Pubmed	Partial rescue of the amelogenin null dental enamel phenotype.	AMELX AMELY	2.37e-06	2	54	2	18390542
Pubmed	Folding, assembly, and aggregation of recombinant murine amelogenins with T21I and P41T point mutations.	AMELX AMELY	2.37e-06	2	54	2	21540557
Pubmed	The energetic basis for hydroxyapatite mineralization by amelogenin variants provides insights into the origin of amelogenesis imperfecta.	AMELX AMELY	2.37e-06	2	54	2	31239344
Pubmed	Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis.	AMELX AMELY	2.37e-06	2	54	2	19097165
Pubmed	A solution NMR investigation into the murine amelogenin splice-variant LRAP (Leucine-Rich Amelogenin Protein).	AMELX AMELY	2.37e-06	2	54	2	20304108
Pubmed	Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate.	AMELX AMELY	2.37e-06	2	54	2	24362885
Pubmed	Two related low molecular mass polypeptide isoforms of amelogenin have distinct activities in mouse tooth germ differentiation in vitro.	AMELX AMELY	2.37e-06	2	54	2	15647828
Pubmed	DNA sequence for cloned cDNA for murine amelogenin reveal the amino acid sequence for enamel-specific protein.	AMELX AMELY	2.37e-06	2	54	2	4015654
Pubmed	Weaker dental enamel explains dental decay.	AMELX AMELY	2.37e-06	2	54	2	25885796
Pubmed	Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.	BCL9L BCL9	2.37e-06	2	54	2	20682801
Pubmed	Structural variation of the pseudoautosomal region between and within inbred mouse strains.	AMELX AMELY	2.37e-06	2	54	2	8552598
Pubmed	BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer.	BCL9L BCL9	2.37e-06	2	54	2	33767438
Pubmed	The amelogenin C-terminus is required for enamel development.	AMELX AMELY	2.37e-06	2	54	2	20042744
Pubmed	Leucine rich amelogenin peptide prevents ovariectomy-induced bone loss in mice.	AMELX AMELY	2.37e-06	2	54	2	34780561
Pubmed	Comparison of upstream regions of X- and Y-chromosomal amelogenin genes.	AMELX AMELY	2.37e-06	2	54	2	9714776
Pubmed	Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor.	AMELX AMELY	2.37e-06	2	54	2	31919099
Pubmed	The small bovine amelogenin LRAP fails to rescue the amelogenin null phenotype.	AMELX AMELY	2.37e-06	2	54	2	12958690
Pubmed	[Types and frequencies of variants in Amelogenin gene in Chinese population].	AMELX AMELY	2.37e-06	2	54	2	18067069
Pubmed	CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.	CCDC74B CCDC74A	2.37e-06	2	54	2	31521166
Pubmed	The circadian clock modulates enamel development.	AMELX AMELY	2.37e-06	2	54	2	22653892
Interaction	EWSR1 interactions	TRIM33 BCL9L HNF1B IL16 OTX1 SF3B4 OGT TCF20 CECR2 RANBP9 MAML1 DACH1 U2AF2 BCL9	5.82e-08	906	53	14	int:EWSR1
Interaction	SMG7 interactions	TRIM66 KMT2D TCF20 ATXN2 MAML1 DACH1 U2AF2 BCL9 ABTB2	1.34e-07	319	53	9	int:SMG7
Interaction	AR interactions	FOXO1 TRIM33 BCL9L KMT2D OGT TCF20 RANBP9 MAML1 MED14 MED12L U2AF2 TAB2 BCL9 TNS1	1.78e-07	992	53	14	int:AR
Interaction	SOX17 interactions	TRIM33 HNF1B KMT2D TCF20 NKX2-4 BCL9	1.80e-07	95	53	6	int:SOX17
Interaction	DACH1 interactions	FOXO1 TFEB HNF1B DACH1 U2AF2 TBX2	3.08e-07	104	53	6	int:DACH1
Interaction	TBR1 interactions	BCL9L HNF1B KMT2D NKX2-4 MAML1 BCL9	5.04e-07	113	53	6	int:TBR1
Interaction	TLX3 interactions	TBX15 BCL9L HNF1B KMT2D TCF20 MAML1 BCL9 MEIS1	8.66e-07	291	53	8	int:TLX3
Interaction	SP7 interactions	TRIM33 BCL9L HNF1B KMT2D TCF20 NKX2-4 MAML1 BCL9	1.20e-06	304	53	8	int:SP7
Interaction	SOX7 interactions	TRIM33 KMT2D TCF20 CECR2 MAML1	2.43e-06	82	53	5	int:SOX7
Interaction	CRX interactions	TRIM33 BCL9L HNF1B KMT2D TCF20 MAML1 BCL9	4.37e-06	254	53	7	int:CRX
Interaction	TLE3 interactions	TBX15 BCL9L HNF1B KMT2D TCF20 CECR2 MAML1 BCL9	5.80e-06	376	53	8	int:TLE3
Interaction	TLX1 interactions	KMT2D TCF20 MAML1 DACH1 BCL9 MEIS1	6.44e-06	175	53	6	int:TLX1
Interaction	TFEB interactions	FOXO1 TFEB DACH1 TBX2	1.05e-05	52	53	4	int:TFEB
Interaction	PAX8 interactions	HNF1B KMT2D NKX2-4 MAML1 BCL9	1.08e-05	111	53	5	int:PAX8
Interaction	SOX2 interactions	TFEB TRIM33 BCL9L HNF1B KMT2D OGT SALL3 TCF20 RANBP9 MAML1 DACH1 MAP3K13 BCL9 TBX2	1.25e-05	1422	53	14	int:SOX2
Interaction	NUP35 interactions	TRIM33 BCL9L HNF1B KMT2D TCF20 ATXN2 MAML1 BCL9	1.39e-05	424	53	8	int:NUP35
Interaction	PAX7 interactions	HNF1B KMT2D MAML1 DACH1 BCL9	1.84e-05	124	53	5	int:PAX7
Interaction	YAP1 interactions	FOXO1 TFEB BCL9L HNF1B KMT2D OGT TCF20 TLN1 MED14 DACH1 FOXJ3 TBX2	2.09e-05	1095	53	12	int:YAP1
Interaction	PAX9 interactions	BCL9L KMT2D TCF20 MAML1 BCL9	2.31e-05	130	53	5	int:PAX9
Interaction	NFIB interactions	HNF1B KMT2D NKX2-4 MAML1 BCL9	3.54e-05	142	53	5	int:NFIB
Interaction	TLX2 interactions	HNF1B KMT2D TCF20 BCL9 MEIS1	3.54e-05	142	53	5	int:TLX2
Interaction	EYA4 interactions	HNF1B SF3B4 OGT MAML1 BCL9 FOXJ3	4.13e-05	243	53	6	int:EYA4
Interaction	PAX2 interactions	HNF1B KMT2D NKX2-4 BCL9	7.37e-05	85	53	4	int:PAX2
Interaction	LHX4 interactions	TRIM33 BCL9L HNF1B KMT2D BCL9	7.44e-05	166	53	5	int:LHX4
Interaction	EGR2 interactions	TRIM33 BCL9L KMT2D MAML1 BCL9	8.56e-05	171	53	5	int:EGR2
Interaction	ALG13 interactions	TRIM66 KMT2D TCF20 ATXN2 BCL9	1.18e-04	183	53	5	int:ALG13
Interaction	HNF1B interactions	HNF1B KMT2D MAML1 DACH1 BCL9	1.40e-04	190	53	5	int:HNF1B
Interaction	CREBBP interactions	FOXO1 TRIM33 HNF1B KMT2D OGT MAML1 DACH1 MEIS1	1.58e-04	599	53	8	int:CREBBP
Interaction	TBX2 interactions	TFEB DACH1 TBX2	1.58e-04	40	53	3	int:TBX2
Interaction	FEV interactions	KMT2D TCF20 MAML1 DACH1 BCL9	1.91e-04	203	53	5	int:FEV
Interaction	SRSF11 interactions	FOXO1 TRIM33 OGT DACH1 U2AF2	1.91e-04	203	53	5	int:SRSF11
Interaction	LDB1 interactions	TRIM33 BCL9L HNF1B BCL9	2.37e-04	115	53	4	int:LDB1
Interaction	HNRNPD interactions	FOXO1 SF3B4 OGT ATXN2 TLN1 MED14 U2AF2 TLN2	2.43e-04	638	53	8	int:HNRNPD
Interaction	TBXT interactions	KMT2D TCF20 MAML1 BCL9	2.45e-04	116	53	4	int:TBXT
Interaction	PYGO2 interactions	BCL9L KMT2D BCL9	2.73e-04	48	53	3	int:PYGO2
Interaction	ERG interactions	TRIM33 KMT2D TCF20 MAML1 BCL9	2.95e-04	223	53	5	int:ERG
Interaction	HMG20B interactions	HNF1B SF3B4 RANBP9 U2AF2	2.98e-04	122	53	4	int:HMG20B
Interaction	SEPTIN7 interactions	KMT2D OGT MLIP TLN1 U2AF2	3.27e-04	228	53	5	int:SEPTIN7
Interaction	CEBPA interactions	TRIM33 KMT2D OGT TCF20 ATXN2 TLN1 MAML1 MED14 DACH1 BCL9 FOXJ3	3.30e-04	1245	53	11	int:CEBPA
Interaction	NCOR1 interactions	TFEB TRIM33 HNF1B DACH1 TAB2 TBX2	3.68e-04	363	53	6	int:NCOR1
Interaction	RGCC interactions	TLN1 TLN2	4.40e-04	12	53	2	int:RGCC
Interaction	MLKL interactions	TRIM33 TRIM66 CECR2	4.55e-04	57	53	3	int:MLKL
Interaction	LHX6 interactions	TRIM33 BCL9L BCL9	4.78e-04	58	53	3	int:LHX6
Interaction	FMR1 interactions	TCF20 ATXN2 CECR2 IQSEC2 RANBP9 BCL9 TNS1	4.84e-04	536	53	7	int:FMR1
Interaction	SSBP4 interactions	TRIM33 BCL9L BCL9	5.03e-04	59	53	3	int:SSBP4
Interaction	HDAC1 interactions	HNF1B KMT2D IKZF2 OGT TCF20 TLN1 RANBP9 DACH1 U2AF2 TAB2	5.43e-04	1108	53	10	int:HDAC1
Interaction	HOXA10 interactions	FOXO1 MEIS1 TBX2	5.82e-04	62	53	3	int:HOXA10
Cytoband	Ensembl 112 genes in cytogenetic band chr18q23	SALL3 ZNF236	1.03e-03	40	54	2	chr18q23
Cytoband	2q21.1	CCDC74B CCDC74A	2.15e-03	58	54	2	2q21.1
GeneFamily	T-boxes	TBX15 TBX2	6.44e-04	18	38	2	766
GeneFamily	PHD finger proteins	TRIM33 TRIM66 KMT2D	8.87e-04	90	38	3	88
GeneFamily	Ataxins\|Trinucleotide repeat containing	KMT2D ATXN2	1.25e-03	25	38	2	775
GeneFamily	Cyclins\|Mediator complex	MED14 MED12L	2.18e-03	33	38	2	1061
GeneFamily	Forkhead boxes	FOXO1 FOXJ3	3.68e-03	43	38	2	508
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	TLN1 TLN2	4.94e-03	50	38	2	1293
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF18 IKZF2 SALL3 ZNF317 ZNF236	1.65e-02	718	38	5	28
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM33 TRIM66	1.70e-02	95	38	2	59
Coexpression	GSE36009_UNSTIM_VS_LPS_STIM_DC_DN	TRIM33 OGT ADO ATXN2 MAML1 TAB2 CPD	1.77e-07	200	54	7	M8774
Coexpression	MURARO_PANCREAS_BETA_CELL	FOXO1 USF3 ATXN2 TAB2 CPD BCL9 FOXJ3 TNS1 ZC3H6 CDC37L1	2.02e-05	946	54	10	M39169
Coexpression	GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP	TFEB TRIM33 KMT2D MAML1 FOXJ3	5.22e-05	196	54	5	M5381
Coexpression	GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_DN	FOXO1 ZNF18 IL16 TCF20 BCL9	5.74e-05	200	54	5	M7075
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#5_top-relative-expression-ranked_1000	OGT MED14 MED12L DACH1 ARHGEF12 CPD CDC37L1	1.26e-06	226	52	7	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k5
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500	OGT MED14 MED12L DACH1 CPD ZC3H6	2.84e-06	163	52	6	gudmap_developingKidney_e15.5_cortic collect duct_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	IKZF2 OGT SALL3 MED14 DACH1 CPD BCL9 FOXJ3 ZC3H6 ABTB2	1.46e-05	769	52	10	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000	HNF1B IKZF2 OGT CECR2 MED14 MED12L DACH1 CPD BCL9 MEIS1	1.94e-05	795	52	10	gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500	IKZF2 OGT MED14 MED12L DACH1 CPD ZC3H6	4.39e-05	390	52	7	gudmap_developingKidney_e15.5_cortic collect duct_500
CoexpressionAtlas	Stem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1	MED12L DACH1 TNS1 MEIS1	5.09e-05	83	52	4	GSM476663_100
CoexpressionAtlas	Stem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1	IKZF2 MED12L DACH1 ARHGEF12 TNS1 ZC3H6 MEIS1	5.92e-05	409	52	7	GSM476663_500
CoexpressionAtlas	Stem Cells, SC.STSL.BM, CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Bone marrow, avg-3	IKZF2 MED12L DACH1 ARHGEF12 TNS1 MEIS1 KLHL4	7.31e-05	423	52	7	GSM399454_500
CoexpressionAtlas	Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3	IKZF2 MED12L DACH1 MEIS1	7.62e-05	92	52	4	GSM791126_100
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000	HNF1B IKZF2 OGT MED14 MED12L DACH1 CPD BCL9 TBX2	1.27e-04	801	52	9	gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000	OGT MED14 MED12L DACH1 CPD	1.37e-04	203	52	5	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000	OGT MED14 CPD BCL9 ZC3H6	1.57e-04	209	52	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_1000	OGT SALL3 TLN1 MED14 MED12L DACH1 ARHGEF12 CPD CDC37L1	1.76e-04	837	52	9	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000
CoexpressionAtlas	Stem Cells, SC.LT34F.BM, Lineage- cKit+ Sca-1+ flk2- CD34-, Bone marrow, avg-3	IKZF2 MED12L DACH1 TNS1 MEIS1 KLHL4	2.59e-04	365	52	6	GSM791102_500
CoexpressionAtlas	alpha beta T cells, T.4SP69+.Th, 4+ 8- TCRhi 69+, Thymus, avg-3	FOXO1 IKZF2 TCF20 MED14 BCL9 ABTB2	2.59e-04	365	52	6	GSM399376_500
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	IKZF2 OGT MED14 MED12L DACH1 CPD	3.16e-04	379	52	6	gudmap_developingKidney_e15.5_1000_k3
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FOXO1 IL16 TLN2 TNS1 MEIS1 TBX2	1.29e-07	194	54	6	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	TRIM33 USF3 USP32 CPD BCL9	3.68e-06	193	54	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	remission-multiplets\|World / disease stage, cell group and cell class	IKZF2 MED12L DACH1 TNS1	2.66e-05	142	54	4	286d01b4f95e9c0b38b91958f925f3797dffd596
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 CECR2 MED12L DACH1	2.66e-05	142	54	4	5b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF18 IL16 CCDC74A ABTB2	2.66e-05	142	54	4	199a0a1024b6cc446f5ca1f277846a2bdb227a9f
ToppCell	remission-multiplets\|remission / disease stage, cell group and cell class	IKZF2 MED12L DACH1 TNS1	3.21e-05	149	54	4	e9974260a5f2999b363f306cae005698c912893a
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright\|ICU-NoSEP / Disease, Lineage and Cell Type	MED14 DACH1 BCL9 ZNF236	5.01e-05	167	54	4	f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	CECR2 RANBP9 ARHGEF12 MAP3K13	5.37e-05	170	54	4	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ESPN ZNF18 IL16 IKZF2	5.37e-05	170	54	4	bda900c836e0f2c1d7b442beb50b672d025b2420
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FOXO1 TFEB USP32 KLHL4	5.62e-05	172	54	4	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXO1 TLN2 TNS1 TBX2	6.01e-05	175	54	4	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DACH1 TLN2 ABTB2 TBX2	6.70e-05	180	54	4	788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL16 DACH1 MEIS1 TBX2	6.85e-05	181	54	4	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 DACH1 ABTB2 TBX2	7.61e-05	186	54	4	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 HNF1B CPD TNS1	7.77e-05	187	54	4	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	severe_influenza-RBC\|World / disease group, cell group and cell class (v2)	ESPN ARHGEF12 TLN2 TNS1	7.77e-05	187	54	4	f846750575f318503d21ade30f5bfd2e1d4c84af
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HNF1B SALL3 CECR2 ABTB2	7.77e-05	187	54	4	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DACH1 TNS1 MEIS1 TBX2	7.77e-05	187	54	4	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	IL16 TLN2 MEIS1 TBX2	7.77e-05	187	54	4	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	IL16 TLN2 ABTB2 MEIS1	7.93e-05	188	54	4	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	Influenza_Severe-RBC\|World / Disease group and Cell class	ESPN ARHGEF12 TLN2 TNS1	7.93e-05	188	54	4	f0438e6a77ee1f0456cb65926685266fff470983
ToppCell	IPF-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	FOXO1 IKZF2 ARHGEF12 TAB2	8.10e-05	189	54	4	7a260485c2a7c743c14d048e5e480ae0a9b8e32c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 CECR2 MED12L DACH1	8.10e-05	189	54	4	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DACH1 ARHGEF12 MEIS1 TBX2	8.26e-05	190	54	4	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 CECR2 MED12L DACH1	8.26e-05	190	54	4	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DACH1 ARHGEF12 MEIS1 TBX2	8.43e-05	191	54	4	f229abf69a1217194f74b0502486907e07dba989
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 CECR2 ABTB2 MEIS1	8.43e-05	191	54	4	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DACH1 ARHGEF12 TLN2 TBX2	8.60e-05	192	54	4	35f7926628a967f85b26371e795a1b93c6f103ab
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	ESPN MED12L DACH1 TBX2	8.60e-05	192	54	4	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL16 DACH1 MEIS1 TBX2	8.78e-05	193	54	4	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FOXO1 IL16 MEIS1 TBX2	8.78e-05	193	54	4	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	HSPCs-Mk_prog.\|World / Lineage and Cell class	TLN1 MED12L DACH1 MEIS1	8.95e-05	194	54	4	5049f4f102844d766eca577e809cf21f7908a9d2
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	IL16 DACH1 MEIS1 TBX2	9.13e-05	195	54	4	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	IL16 DACH1 MEIS1 TBX2	9.13e-05	195	54	4	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL16 TLN2 MEIS1 TBX2	9.32e-05	196	54	4	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	USP32 TLN2 ABTB2 TBX2	9.50e-05	197	54	4	d7cef7881abd807a679432766ced609a6efd1067
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	USP32 TLN2 ABTB2 TBX2	9.50e-05	197	54	4	20a5958512bdb99daeb8f4d244df53e4f048f879
ToppCell	T_cells-Treg_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	FOXO1 IL16 IKZF2 TAB2	9.50e-05	197	54	4	de5448fcdf4e433fc167496413abe5d0c8a5c6d8
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	OTX1 CPD TNS1 MEIS1	9.88e-05	199	54	4	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	Sepsis-Leuk-UTI-Myeloid-tDC\|Leuk-UTI / Disease, condition lineage and cell class	USP32 MED12L DACH1 MAP3K13	9.88e-05	199	54	4	a2f154b15087803958a656d2a41b6d83fd37b32f
ToppCell	Influenza-Influenza_Severe-Others-RBC\|Influenza_Severe / Disease, condition lineage and cell class	ESPN ARHGEF12 TLN2 TNS1	9.88e-05	199	54	4	da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	OTX1 MAML1 DACH1 TAB2	9.88e-05	199	54	4	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 DACH1 MEIS1 TBX2	1.01e-04	200	54	4	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	COVID-19-COVID-19_Severe-Others-RBC\|COVID-19_Severe / Disease, condition lineage and cell class	ESPN ARHGEF12 TLN2 TNS1	1.01e-04	200	54	4	308f74e7e13ecc6d133c219c42cc8895a96644c8
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 DACH1 MEIS1 TBX2	1.01e-04	200	54	4	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-NoSEP / Disease, condition lineage and cell class	MED14 DACH1 BCL9 ZNF236	1.01e-04	200	54	4	c2df917900872453ea17a39928e39d071a6d3339
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 DACH1 MEIS1 TBX2	1.01e-04	200	54	4	fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 CCDC74A ABTB2	6.93e-04	143	54	3	990844ca674d30b2924c74b45bed4fdfb8463fa7
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX15 HNF1B TLN2	7.07e-04	144	54	3	1d05aa08603cba28c0c6511767e434c1f592a3aa
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-5\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	OTX1 IKZF2 MAP3K13	7.07e-04	144	54	3	76c0e551864c4faab7528c4ecf1a40d7ea60569f
ToppCell	ASK454-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	SF3B4 USP32 U2AF2	7.07e-04	144	54	3	8e693b50bd6c69ce68f44ca6e51f6d0c7f80d82c
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DACH1 MEIS1 TBX2	7.07e-04	144	54	3	1c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX15 HNF1B TLN2	7.07e-04	144	54	3	d3f6f5da56794367ee3776bfd3a9dcf893efe0f0
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KMT2D TCF20 MEIS1	7.95e-04	150	54	3	744050a1b665c6989f37141348af3df7579a73c9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 ABTB2 TBX2	7.95e-04	150	54	3	87968ce885a4959616f0321f58517fe8029ba1b1
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FOXO1 TLN2 TBX2	8.42e-04	153	54	3	1524557514668f515ac1bbe847611f564b265b42
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TBX15 ESPN MAP3K13	8.91e-04	156	54	3	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TBX15 ESPN MAP3K13	8.91e-04	156	54	3	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DACH1 ABTB2 TBX2	9.07e-04	157	54	3	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	frontal_cortex-Non-neuronal-smooth_muscle_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX15 TNS1 TBX2	9.24e-04	158	54	3	08806240228c5b780f5aef92ce2c278ae4d797cc
ToppCell	frontal_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX15 TNS1 TBX2	9.24e-04	158	54	3	496b6988f7b3439968351840ae22f56ffa1643f1
ToppCell	frontal_cortex-Non-neuronal-smooth_muscle_cell-SMC\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX15 TNS1 TBX2	9.24e-04	158	54	3	5b3d30f92b619f14a7b48502170000fa5783358a
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	TNS1 MEIS1 TBX2	9.41e-04	159	54	3	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 MED12L DACH1	9.58e-04	160	54	3	2d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 MED12L DACH1	9.58e-04	160	54	3	8bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	IKZF2 MED12L TAB2	9.93e-04	162	54	3	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 USF3 MED12L	9.93e-04	162	54	3	e81dec1db8e5a808d96e58410c91961e5d065c94
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 USF3 MED12L	9.93e-04	162	54	3	d19b469f64c9064cfb82dadb6c8135e28949a02a
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 USF3 MED12L	9.93e-04	162	54	3	10c2aa047f33f48e4abe676236bbdb593079dd1d
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN IKZF2 ZC3H6	1.01e-03	163	54	3	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN IKZF2 ZC3H6	1.01e-03	163	54	3	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-Mesoderm\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	MLIP DACH1	1.02e-03	39	54	2	3479d255b87fa8042c51d80a3eb81a774850132e
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL9L SEC22C FOXJ3	1.03e-03	164	54	3	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL9L SEC22C FOXJ3	1.03e-03	164	54	3	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL9L SEC22C FOXJ3	1.03e-03	164	54	3	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	MED12L DACH1 MEIS1	1.05e-03	165	54	3	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TNS1 MEIS1 TBX2	1.05e-03	165	54	3	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FOXO1 TLN2 MEIS1	1.07e-03	166	54	3	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	ESPN MEIS1 TBX2	1.07e-03	166	54	3	773673a5d0430640439845b264740bfbbdad0cb2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FOXO1 OGT MLIP	1.08e-03	167	54	3	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	ESPN MEIS1 TBX2	1.08e-03	167	54	3	3ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ESPN TRIM66 TBX2	1.08e-03	167	54	3	6c2dade24a88af04b2c90a7e4f8dd7ccea9e94d1
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	DACH1 MEIS1 TBX2	1.08e-03	167	54	3	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	Control-NK\|Control / Disease group and Cell class	IQSEC2 ABTB2 MEIS1	1.10e-03	168	54	3	683d389c8a1e791bfc773e63148115a21a6566db
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Spindle_Cell-1\|TCGA-Uvea / Sample_Type by Project: Shred V9	SF3B4 TLN1 TNS1	1.10e-03	168	54	3	b427746929bb40e3d1b5f1c40d302b792d6b32a5
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ESPN TRIM66 TBX2	1.10e-03	168	54	3	d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF18 MED12L ZNF236	1.12e-03	169	54	3	bca5322880c09b78ef10d9dda6420a80c1ba7e62
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 DACH1 TBX2	1.12e-03	169	54	3	0332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DACH1 MEIS1 TBX2	1.12e-03	169	54	3	6ff1172da690ca17f7108f1617b255b766971a57
ToppCell	severe-Myeloid-Eosinophils\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IKZF2 DACH1 ABTB2	1.14e-03	170	54	3	863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCell	droplet-Spleen-nan-3m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DACH1 CPD BCL9	1.14e-03	170	54	3	dbd6c9c7be824a1ff1b31af791064127cafbd194
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL16 IKZF2 SEC22C	1.16e-03	171	54	3	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	DACH1 TNS1 TBX2	1.16e-03	171	54	3	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	normal-na-Lymphocytic_NK-natural_killer_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CCDC74A TLN2 MEIS1	1.16e-03	171	54	3	d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCell	mild-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IKZF2 DACH1 ABTB2	1.16e-03	171	54	3	5c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HNF1B DACH1 TLN2	1.18e-03	172	54	3	c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic-Meg\|bone_marrow / Manually curated celltypes from each tissue	MED12L TNS1 MEIS1	1.18e-03	172	54	3	deda14ba1e760dd46a5e129683d415436e74deb6
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HNF1B DACH1 TLN2	1.18e-03	172	54	3	bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TLN2 TNS1 MEIS1	1.20e-03	173	54	3	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 CECR2 DACH1	1.20e-03	173	54	3	4bc6d93716f093b460c8b047199db8cab5fea720
Computational	Neighborhood of HBP1	SF3B4 RANBP9 TAB2 FOXJ3	9.26e-05	70	37	4	GCM_HBP1
Drug	Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HG-U133A	FOXO1 TRIM66 ATXN2 RANBP9 TLN2 BCL9 TBX2	3.96e-07	196	54	7	1930_UP
Drug	Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; PC3; HT_HG-U133A	TFEB TLN1 IQSEC2 ARHGEF12 TLN2 BCL9	6.71e-06	195	54	6	2087_UP
Drug	Iobenguane sulfate; Down 200; 10.8uM; PC3; HT_HG-U133A	TRIM66 HNF1B MED14 ARHGEF12 TNS1 TBX2	7.32e-06	198	54	6	7299_DN
Drug	ganoine	AMELX AMELY	1.65e-05	3	54	2	CID000131592
Drug	Econazole nitrate [24169-02-6]; Down 200; 9uM; PC3; HT_HG-U133A	ARHGEF12 U2AF2 CPD TNS1 MEIS1	8.72e-05	190	54	5	7305_DN
Drug	Hymecromone [90-33-5]; Down 200; 22.8uM; PC3; HT_HG-U133A	HNF1B IQSEC2 RANBP9 TLN2 TAB2	9.38e-05	193	54	5	4623_DN
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A	TFEB HNF1B ATXN2 TLN2 TNS1	9.61e-05	194	54	5	3807_DN
Drug	5194442; Up 200; 20uM; PC3; HT_HG-U133A	TRIM66 IQSEC2 MED14 TNS1 TBX2	9.61e-05	194	54	5	6553_UP
Drug	Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	TRIM66 MAML1 MED14 BCL9 CDC37L1	9.85e-05	195	54	5	5287_UP
Drug	Flufenamic acid [530-78-9]; Down 200; 14.2uM; HL60; HG-U133A	TRIM33 IL16 ATXN2 MED14 U2AF2	9.85e-05	195	54	5	1420_DN
Drug	CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A	FOXO1 TFEB ATXN2 IQSEC2 TNS1	1.01e-04	196	54	5	4560_DN
Drug	Mafenide hydrochloride [138-37-4]; Down 200; 18uM; PC3; HT_HG-U133A	FOXO1 ARHGEF12 BCL9 TNS1 ABTB2	1.01e-04	196	54	5	5079_DN
Drug	Midecamycin [35457-80-8]; Down 200; 5uM; PC3; HT_HG-U133A	OGT TLN1 U2AF2 CPD TNS1	1.01e-04	196	54	5	6745_DN
Drug	Bezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A	IQSEC2 DACH1 ARHGEF12 TLN2 TNS1	1.03e-04	197	54	5	2630_UP
Drug	Equilin [474-86-2]; Down 200; 15uM; HL60; HT_HG-U133A	FOXO1 TRIM33 MAML1 MED14 TLN2	1.03e-04	197	54	5	3039_DN
Drug	Ricinine [524-40-3]; Up 200; 24.4uM; PC3; HT_HG-U133A	TFEB TRIM33 IQSEC2 TLN2 TBX2	1.03e-04	197	54	5	5725_UP
Drug	Bemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A	OGT IQSEC2 TLN2 TAB2 TNS1	1.06e-04	198	54	5	6668_DN
Drug	Clopamide [636-54-4]; Down 200; 11.6uM; PC3; HT_HG-U133A	FOXO1 TLN1 TNS1 CDC37L1 MEIS1	1.06e-04	198	54	5	6301_DN
Drug	Nabumetone [42924-53-8]; Up 200; 17.6uM; PC3; HT_HG-U133A	FOXO1 IL16 ARHGEF12 TLN2 ZNF236	1.06e-04	198	54	5	6327_UP
Drug	Tiletamine hydrochloride; Down 200; 15.4uM; PC3; HT_HG-U133A	FOXO1 MED14 ARHGEF12 U2AF2 TNS1	1.08e-04	199	54	5	7311_DN
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; PC3; HT_HG-U133A	AMELX DACH1 TLN2 ZNF236 TNS1	1.08e-04	199	54	5	4485_UP
Drug	Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; PC3; HT_HG-U133A	TFEB MAML1 TLN2 ZNF236 TBX2	1.08e-04	199	54	5	3701_DN
Drug	Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; PC3; HT_HG-U133A	FOXO1 ARHGEF12 U2AF2 TLN2 BCL9	1.11e-04	200	54	5	2082_UP
Disease	amelogenesis imperfecta type 1E (implicated_via_orthology)	AMELX AMELY	2.93e-06	2	51	2	DOID:0110058 (implicated_via_orthology)
Disease	autosomal dominant hypocalcemia (biomarker_via_orthology)	AMELX AMELY	1.75e-05	4	51	2	DOID:0090109 (biomarker_via_orthology)
Disease	procollagen C-endopeptidase enhancer 2 measurement	ZNF18 ATXN2	4.37e-05	6	51	2	EFO_0801921
Disease	total blood protein measurement	HNF1B KMT2D ADO ATXN2 ARHGEF12 TAB2	1.21e-04	449	51	6	EFO_0004536
Disease	diastolic blood pressure, systolic blood pressure	TBX15 TRIM33 ATXN2 RANBP9 MAML1 TLN2 BCL9	1.47e-04	670	51	7	EFO_0006335, EFO_0006336
Disease	arterial stiffness measurement	FOXO1 TCF20 MAP3K13	1.88e-04	64	51	3	EFO_0004517
Disease	mean arterial pressure	ADO TCF20 ATXN2 ARHGEF12 TNS1 TBX2	2.15e-04	499	51	6	EFO_0006340
Disease	triacylglycerol 48:4 measurement	DACH1 ZNF236	2.63e-04	14	51	2	EFO_0010407
Disease	neutrophil count	TBX15 FOXO1 TRIM33 ATXN2 IQSEC2 MAML1 ARHGEF12 TLN2 BCL9	5.43e-04	1382	51	9	EFO_0004833
Disease	eye measurement	FOXO1 ATXN2	1.00e-03	27	51	2	EFO_0004731
Disease	blood urea nitrogen measurement	TFEB HNF1B IKZF2 ATXN2 DACH1	1.09e-03	452	51	5	EFO_0004741
Disease	myeloid white cell count	TBX15 IKZF2 ATXN2 MED12L ARHGEF12 TLN2 BCL9	1.09e-03	937	51	7	EFO_0007988
Disease	triacylglycerol 50:4 measurement	DACH1 ZNF236	1.24e-03	30	51	2	EFO_0010411
Disease	systolic blood pressure, body mass index	ATXN2 BCL9	1.59e-03	34	51	2	EFO_0004340, EFO_0006335
Disease	monocyte count	FOXO1 ADO ATXN2 CECR2 TLN1 MED12L ARHGEF12 MEIS1	1.80e-03	1320	51	8	EFO_0005091
Disease	hypertension	ATXN2 ARHGEF12 TAB2 TBX2	1.95e-03	307	51	4	EFO_0000537
Disease	Congenital small ears	KMT2D SF3B4	2.30e-03	41	51	2	C0152423
Disease	smoking status measurement, carotid artery intima media thickness	ESPN TRIM33	3.14e-03	48	51	2	EFO_0006527, EFO_0007117
Disease	autism	TRIM33 AMELY	3.14e-03	48	51	2	EFO_0003758
Disease	alopecia areata	ADO ATXN2	3.40e-03	50	51	2	EFO_0004192
Disease	platelet-to-lymphocyte ratio	FOXO1 MED12L CDC37L1 MEIS1	3.57e-03	363	51	4	EFO_0008446

Protein segments in the cluster

Peptide	Gene	Start	Entry
MPVPGQHSMTPIQHH	AMELX	101	Q99217
MPVPGQQSMTPTQHH	AMELY	116	Q99218
GTSIPLHDHPGMHGM	ADO	106	Q96SZ5
QHQGRQMGAGAHPPM	CCDC74A	246	Q96AQ1
QHQGRQMGAAAHPPM	CCDC74B	246	Q96LY2
NSHIMPHSVPGLMSP	DACH1	301	Q9UI36
QMCGGLTHLSNMGPH	CECR2	711	Q9BXF3
IGHMSPIMTSPHSPG	ARHGEF12	166	Q9NZN5
TSSHPEMLHGMAPQQ	MLIP	186	Q5VWP3
MSPSHGMNIHNLASG	RANBP9	486	Q96S59
PHTAHTNAMAPSMGS	MEIS1	51	O00470
GNLMPMGPGHASVSS	MAML1	716	Q92585
TVAGMQPSHAMAGHN	NKX2-4	61	Q9H2Z4
HSPHMMIGPNNSSIG	MED12L	316	Q86YW9
PHMAHVPQAHVQSGM	ATXN2	1241	Q99700
SHHPQMMPAAGAAGG	IQSEC2	1391	Q5JU85
GMTPLHAAAQMGHSP	ESPN	206	B1AK53
SPIMSENHGHMPLQP	IL16	726	Q14005
SMEAAGQVMSHHVPP	IKZF2	226	Q9UKS7
MPPMSTHRHGLGVAT	KLHL4	506	Q9C0H6
PHQLSPMAPSSMAGH	OTX1	261	P32242
PSMMHTQSPGNLHAA	MED14	1036	O60244
PAMSQSHHPRLNMHG	MAP3K13	646	O43283
MMNPSSHTHPGHAQQ	FOXO1	516	Q12778
AMHPTKPSQHIGTGN	FOXJ3	536	Q9UPW0
PGLMSHNPIMGHGSQ	BCL9	1111	O00512
HNPIMGHGSQEPPMV	BCL9	1116	O00512
INQMGSPGMGHLKSP	BCL9L	921	Q86UU0
HNTRIHLMPSMNPDG	CPD	596	O75976
VQTVSMHGLMHPNGA	CCDC168	4761	Q8NDH2
ANGVMNGHTPMHLEP	SEC22C	161	Q9BRL7
QHIRMHMGGQIPNTP	SALL3	756	Q9BXA9
PMTVQNHVPHSGVGS	CDC37L1	281	Q7L3B6
GNHPTSHLMQSIPGM	OGT	566	O15294
PHQQPLMQQSPGSHM	HNF1B	481	P35680
SMMQPHLQRQHSNPG	TRIM33	611	Q9UPN9
GNSAPNSPMAMLHIG	TFEB	136	P19484
NMSGQVSMGPAFIHH	TAB2	421	Q9NYJ8
GMEHSMHMISPSPNN	TBX15	561	Q96SF7
MHHMQGRHPLCPGAS	ABTB2	351	Q8N961
PGPNMSQGHSSPVMH	ZC3H6	481	P61129
QHMLASQGIPMPTFG	TBX2	556	Q13207
TSGQMHRGHMPPLTS	TLN1	476	Q9Y490
APSSPSLSHHQMMGP	TNS1	1206	Q9HBL0
SLSHHQMMGPPGTGF	TNS1	1211	Q9HBL0
TKGHMNPPVTTNMHG	USF3	1931	Q68DE3
PGGDPHHMNPHMTFS	TCF20	1026	Q9UGU0
PGLMSSQVQMGGHPT	U2AF2	361	P26368
GQMHRGHMPPLTSAQ	TLN2	481	Q9Y4G6
GHMPPLTSAQQALMG	TLN2	486	Q9Y4G6
NTHISKMHMGGPQNS	ZNF236	301	Q9UL36
GQHLPNPHSGEMSTM	ZNF18	371	P17022
PPGPACSQNMDIMHH	TRIM66	496	O15016
GMDPHLTQPMGRHAG	ZNF317	176	Q96PQ6
MSQMQLAHHGPHGLG	SF3B4	306	Q15427
TNGMVNGHMPSLPDS	USP32	1056	Q8NFA0
MSHSGQPKLSAQPMG	KMT2D	3881	O14686