Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentnuclear body

PPARGC1A SETX EHMT2 ZC3H13 SETBP1 MKI67 ASCC2 DKC1 GON4L PIP5K1A SREK1 CWC22 REXO1 PRPF18

8.75e-069038114GO:0016604
GeneOntologyCellularComponentnuclear protein-containing complex

MSH6 NABP2 ASCC2 DKC1 GON4L PIP5K1A AFF1 TSEN54 SREK1 NABP1 MGA CWC22 PRPF18 MED12 AFF4 NUP205 RAD50

1.71e-0513778117GO:0140513
GeneOntologyCellularComponentSOSS complex

NABP2 NABP1

8.85e-054812GO:0070876
GeneOntologyCellularComponentsuper elongation complex

AFF1 AFF4

2.20e-046812GO:0032783
GeneOntologyCellularComponentfibrillar center

DKC1 GON4L STOX1 GTF3C3 AFF4

3.52e-04156815GO:0001650
MousePhenodecreased pre-B cell number

MZB1 POLG DKC1 AFF1 RAD50

1.67e-0567675MP:0008209
DomainTF_AF4/FMR2

AFF1 AFF4

1.11e-044812IPR007797
DomainAF-4

AFF1 AFF4

1.11e-044812PF05110
DomainPDZ

GRIP1 RAPGEF6 PCLO GRIP2 RAPGEF2

5.05e-04151815PS50106
Domain-

BAZ2B MECP2

5.11e-0488123.30.890.10
DomainPDZ

GRIP1 RAPGEF6 PCLO GRIP2 RAPGEF2

5.21e-04152815IPR001478
DomainKRAB_RELATED

SSX6P SSX2

9.96e-0411812PS50806
DomainMethyl_CpG_DNA-bd

BAZ2B MECP2

9.96e-0411812IPR001739
DomainMBD

BAZ2B MECP2

9.96e-0411812PF01429
DomainDNA-bd_dom

BAZ2B MECP2

9.96e-0411812IPR016177
DomainMBD

BAZ2B MECP2

9.96e-0411812SM00391
DomainMBD

BAZ2B MECP2

9.96e-0411812PS50982
DomaintRNA_anti-codon

NABP2 NABP1

1.19e-0312812PF01336
DomainNA-bd_OB_tRNA

NABP2 NABP1

1.19e-0312812IPR004365
DomainKrueppel-associated_box-rel

SSX6P SSX2

1.40e-0313812IPR003655
DomainAT_hook

SETBP1 MECP2

2.14e-0316812PF02178
DomainDSRM

SLC4A1AP ADARB2

3.03e-0319812SM00358
DomainPDZ

GRIP1 RAPGEF6 GRIP2 RAPGEF2

3.30e-03141814PF00595
DomainRasGEFN

RAPGEF6 RAPGEF2

3.36e-0320812SM00229
Domaindsrm

SLC4A1AP ADARB2

3.36e-0320812PF00035
DomainRasGEF_N

RAPGEF6 RAPGEF2

3.70e-0321812PF00618
DomainPDZ

GRIP1 RAPGEF6 GRIP2 RAPGEF2

3.93e-03148814SM00228
DomainRas-like_Gua-exchang_fac_N

RAPGEF6 RAPGEF2

4.06e-0322812IPR000651
DomainRASGEF_NTER

RAPGEF6 RAPGEF2

4.06e-0322812PS50212
Domain-

GRIP1 RAPGEF6 GRIP2 RAPGEF2

4.12e-031508142.30.42.10
DomaincEGF

SCUBE1 LRP1

5.64e-0326812IPR026823
DomaincEGF

SCUBE1 LRP1

5.64e-0326812PF12662
DomainAT_hook

SETBP1 MECP2

6.08e-0327812SM00384
DomainAT_hook_DNA-bd_motif

SETBP1 MECP2

6.08e-0327812IPR017956
DomaindsRBD_dom

SLC4A1AP ADARB2

6.53e-0328812IPR014720
DomainFHA

SLC4A1AP MKI67

6.53e-0328812SM00240
DomainRASGEF_CAT

RAPGEF6 RAPGEF2

6.99e-0329812PS50009
DomainRasGEF

RAPGEF6 RAPGEF2

7.47e-0330812PF00617
Domain-

RAPGEF6 RAPGEF2

7.47e-03308121.10.840.10
DomainRas_GEF_dom

RAPGEF6 RAPGEF2

7.47e-0330812IPR023578
DomainRASGEF_cat_dom

RAPGEF6 RAPGEF2

7.47e-0330812IPR001895
DomainRasGEF

RAPGEF6 RAPGEF2

7.47e-0330812SM00147
DomainRA

RAPGEF6 RAPGEF2

7.96e-0331812SM00314
DomainHMGI/Y_DNA-bd_CS

SETBP1 MECP2

7.96e-0331812IPR000637
DomainFHA_DOMAIN

SLC4A1AP MKI67

7.96e-0331812PS50006
DomainFHA

SLC4A1AP MKI67

7.96e-0331812PF00498
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLG MSH6 KRT8 DMXL2 SETX ZC3H13 DKC1 SREK1 LYAR EPB41L3 CWC22 MECP2 MED12 GTF3C3 AFF4 SACM1L NUP205

7.61e-101082841738697112
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SETX SLC4A1AP BAZ2B ZC3H13 MKI67 DKC1 GPATCH4 SREK1 LYAR EPB41L3 SSX2 MGA CWC22 MECP2 AFF4

8.53e-09954841536373674
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

MSH6 SETX SLC4A1AP EHMT2 BAZ2B MKI67 GPATCH4 LYAR MGA MECP2 GTF3C3 AFF4

2.63e-08608841236089195
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

MSH6 KRT8 SETX EHMT2 ZC3H13 WWP2 MKI67 DKC1 ZC3HC1 EPB41L3 USP47

3.73e-08503841116964243
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MSH6 RAPGEF6 SLC4A1AP ZC3H13 MKI67 DKC1 AFF1 MECP2 REXO1 USP47 ANKS1A RAD50

3.54e-07774841215302935
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

KRT8 SETX EHMT2 MGA GTF3C3 RAD50

6.17e-0712584632891193
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

MKI67 GPATCH4 LYAR ZW10 MGA CWC22 MECP2 SPTY2D1 MED12

6.80e-0741084926949251
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RAPGEF6 EHMT2 LRP1 CRYBG3 EPB41L3 MGA MED12 GTF3C3 RAD50

7.98e-0741884934709266
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

MSH6 BAZ2B MGA SPTY2D1 REXO1 AFF4 RAD50

1.17e-0622284737071664
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

MSH6 MKI67 DKC1 GPATCH4 LYAR MGA MECP2 RAD50

2.13e-0634984825665578
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MSH6 EHMT2 LRP1 GPATCH4 SREK1 CRYBG3 RAPGEF2 LYAR EPB41L3 MGA MECP2 AFF4 RAD50

2.70e-061116841331753913
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SETX SLC30A5 EHMT2 MKI67 ZC3HC1 GPATCH4 RAPGEF2 EPB41L3 MGA SPTY2D1 GTF3C3

2.72e-06777841135844135
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

RAPGEF6 ZC3H13 PIP5K1A HEATR5A RAPGEF2 MGA CWC22 ANKS1A

3.84e-0637884834315543
Pubmed

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.

RAPGEF6 MKI67 DKC1 RAPGEF2 LYAR EPB41L3 CWC22

4.28e-0627084724366813
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

MSH6 SLC4A1AP MKI67 DKC1 SREK1 LYAR CWC22 SPTY2D1 GTF3C3 AFF4 NUP205 RAD50

4.51e-06989841236424410
Pubmed

Distinct roles of two SEC scaffold proteins, AFF1 and AFF4, in regulating RNA polymerase II transcription elongation.

AFF1 AFF4

5.76e-06284237528066
Pubmed

Association of the CAG repeat polymorphism in mitochondrial polymerase gamma (POLG1) with male infertility: a case-control study in an Algerian population.

POLG MED12

5.76e-06284234077112
Pubmed

The glutamate receptor-interacting protein family of GluR2-binding proteins is required for long-term synaptic depression expression in cerebellar Purkinje cells.

GRIP1 GRIP2

5.76e-06284218509036
Pubmed

AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.

AFF1 AFF4

5.76e-06284224843025
Pubmed

The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.

RAPGEF6 RAPGEF2

5.76e-06284224858808
Pubmed

Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum.

GRIP1 GRIP2

5.76e-06284231476380
Pubmed

Neoadjuvant therapy in microsatellite-stable colorectal carcinoma induces concomitant loss of MSH6 and Ki-67 expression.

MSH6 MKI67

5.76e-06284228232158
Pubmed

MeCP2 repression of G9a in regulation of pain and morphine reward.

EHMT2 MECP2

5.76e-06284224990928
Pubmed

Disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse.

GRIP1 GRIP2

5.76e-06284224126453
Pubmed

Mice lacking GRIP1/2 show increased social interactions and enhanced phosphorylation at GluA2-S880.

GRIP1 GRIP2

5.76e-06284228063882
Pubmed

NABP1, a novel RORgamma-regulated gene encoding a single-stranded nucleic-acid-binding protein.

NABP2 NABP1

5.76e-06284216533169
Pubmed

Domain and functional analysis of a novel platelet-endothelial cell surface protein, SCUBE1.

SCUBE1 MKI67

5.76e-06284218303018
Pubmed

Histone H3 lysine 9 methyltransferase G9a is a transcriptional coactivator for nuclear receptors.

GRIP1 EHMT2

5.76e-06284216461774
Pubmed

GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions.

GRIP1 GRIP2

5.76e-06284220956289
Pubmed

Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.

AFF1 AFF4

5.76e-06284226007649
Pubmed

Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse.

PPARGC1A POLG

5.76e-06284222357654
Pubmed

Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking.

RAPGEF6 RAPGEF2

5.76e-06284232600317
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

GRIP1 KRT8 NDC80 KATNB1 DKC1 LYAR MGA USP47 NUP205 ANKS1A RAD50

6.60e-06853841128718761
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MYH7 SETX LRP1 MGA MECP2 GTF3C3 ANKRD26P1 USP47 SACM1L NUP205 RAD50

6.90e-06857841125609649
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

MSH6 KRT8 ZC3H13 MKI67 DKC1 PIP5K1A GPATCH4 SREK1 LYAR GTF3C3

8.68e-06713841029802200
Pubmed

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.

NABP2 MKI67 NABP1

9.02e-061784323408915
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

MSH6 KRT8 NDC80 MKI67 DKC1 ZW10

1.24e-0521084616565220
Pubmed

Functional proteomics mapping of a human signaling pathway.

GRIP1 ZBTB6 PSG3 WWP2 LRP1 ASCC2 AFF1 MGA DENND2B

1.32e-0559184915231748
Pubmed

The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.

PPARGC1A MYH7 MYOM3 MKI67

1.49e-056184427166947
Pubmed

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

MSH6 EHMT2 EPB41L3 NUP205 RAD50

1.53e-0512884523858473
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

FLG MSH6 KRT8 ZC3H13 MKI67 ASCC2 DKC1 GPATCH4 LYAR

1.59e-0560584928977666
Pubmed

Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.

NDC80 ZW10

1.73e-05384216732327
Pubmed

GRIP1 is required for homeostatic regulation of AMPAR trafficking.

GRIP1 GRIP2

1.73e-05384226216979
Pubmed

Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism.

GRIP1 GRIP2

1.73e-05384221383172
Pubmed

ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.

LRP1 ANKS1A

1.73e-05384238123547
Pubmed

Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases possessing the Ras/Rap-associating domain.

RAPGEF6 RAPGEF2

1.73e-05384229747665
Pubmed

Sepsis-induced myocardial depression is associated with transcriptional changes in energy metabolism and contractile related genes: a physiological and gene expression-based approach.

PPARGC1A MYH7

1.73e-05384220101178
Pubmed

AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).

AFF1 AFF4

1.73e-05384210588740
Pubmed

Sox2 modulates the function of two distinct cell lineages in mouse skin.

KRT8 PCLO MKI67

1.75e-052184323948231
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

SETX EHMT2 LYAR MECP2 GTF3C3 NUP205 ANKS1A RAD50

1.83e-0546984827634302
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

NDC80 EHMT2 GON4L ZC3HC1 PIP5K1A EPB41L3 MECP2 MED12 RAD50

2.62e-0564584925281560
Pubmed

Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors.

KRT8 PSG3 MKI67

2.65e-052484334233187
Pubmed

Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.

PPARGC1A MKI67 MED12

2.65e-052484325348719
Pubmed

Streamlined analysis schema for high-throughput identification of endogenous protein complexes.

ZC3H13 NABP2 NABP1 MED12

2.72e-057184420133760
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DMXL2 RAPGEF6 SETX SLC30A5 GON4L PIP5K1A CRYBG3 CWC22 SACM1L

2.79e-0565084938777146
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

GRIP1 MSH6 DMXL2 PCLO KATNB1 EPB41L3 ANKS1A RAD50

2.81e-0549884836634849
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MSH6 ZC3H13 MKI67 EPB41L3 MED12 GTF3C3 USP47 NUP205 RAD50

2.89e-0565384922586326
Pubmed

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.

MSH6 SETX NABP2 MKI67 RAD50

3.17e-0514984525184681
Pubmed

The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling.

GRIP1 GRIP2

3.45e-05484212458226
Pubmed

The expression of mismatch repair proteins MLH1, MSH2 and MSH6 correlates with the Ki67 proliferation index and survival in patients with recurrent glioblastoma.

MSH6 MKI67

3.45e-05484220223108
Pubmed

A Minor Subset of Super Elongation Complexes Plays a Predominant Role in Reversing HIV-1 Latency.

AFF1 AFF4

3.45e-05484226830226
Pubmed

Differential Expression of Non-Shelterin Genes Associated with High Telomerase Levels and Telomere Shortening in Plasma Cell Disorders.

DKC1 RAD50

3.45e-05484226366868
Pubmed

The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering.

GRIP1 GRIP2

3.45e-05484211641419
Pubmed

Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4.

AFF1 AFF4

3.45e-05484225282333
Pubmed

Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.

AFF1 AFF4

3.45e-05484211923441
Pubmed

Mediation of Af4 protein function in the cerebellum by Siah proteins.

AFF1 AFF4

3.45e-05484215459319
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MSH6 PCLO MKI67 DKC1 GPATCH4 SREK1 LYAR EPB41L3 CWC22 GTF3C3 SACM1L NUP205 RAD50

3.62e-051425841330948266
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GRIP1 KRT8 RAPGEF6 SETX WWP2 CRYBG3 RAPGEF2 EPB41L3 DENND2B ANKS1A

4.34e-05861841036931259
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

MSH6 EHMT2 MKI67 DKC1 MGA CWC22 MECP2 GTF3C3

4.54e-0553384830554943
Pubmed

Myomesin 3, a novel structural component of the M-band in striated muscle.

MYH7 MYOM3

5.74e-05584218177667
Pubmed

Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus.

KRT8 MKI67

5.74e-05584239164270
Pubmed

Concerted action of histone methyltransferases G9a and PRMT-1 regulates PGC-1α-RIG-I axis in IFNγ treated glioma cells.

PPARGC1A EHMT2

5.74e-05584226725954
Pubmed

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

NABP2 NABP1

5.74e-05584228270450
Pubmed

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity.

NABP2 RAD50

5.74e-05584221227926
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PPARGC1A ZBTB6 RAPGEF6 SETX ZC3H13 POLG GRAMD2B AFF1 MGA SPTY2D1 AFF4

5.96e-051084841111544199
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MSH6 SETX SLC4A1AP EHMT2 ASCC2 GON4L GPATCH4 SREK1 LYAR MECP2 SPTY2D1 MED12 AFF4

6.00e-051497841331527615
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SETX EHMT2 BAZ2B ZC3H13 MKI67 DKC1 GPATCH4 LYAR MGA MECP2 SPTY2D1 RAD50

6.37e-051294841230804502
Pubmed

Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.

GRIP1 PPARGC1A MSH6 RAD50

6.61e-058984418950845
Pubmed

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.

MSH6 KRT8 MKI67 GPATCH4

6.91e-059084435654790
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

MSH6 EHMT2 SREK1 LYAR MGA

7.20e-0517784526206133
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MSH6 ADRA1D SETX BAZ2B ZC3H13 PCLO MYOM3 STOX1 NUP205

7.25e-0573684929676528
Pubmed

Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres.

NABP2 NABP1

8.59e-05684223459151
Pubmed

HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.

NABP2 NABP1

8.59e-05684219605351
Pubmed

KAT8-mediated H4K16ac is essential for sustaining trophoblast self-renewal and proliferation via regulating CDX2.

KRT8 MKI67

8.59e-05684238961108
Pubmed

Uterine glands impact embryo survival and stromal cell decidualization in mice.

KRT8 MKI67

8.59e-05684234547143
Pubmed

The transcription factor Sox10 is an essential determinant of branching morphogenesis and involution in the mouse mammary gland.

KRT8 MKI67

8.59e-05684233082503
Pubmed

SSB1/SSB2 Proteins Safeguard B Cell Development by Protecting the Genomes of B Cell Precursors.

NABP2 NABP1

8.59e-05684231085591
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

FLG MYH7 EHMT2 MKI67 GRIP2 MGA NUP205 ANKS1A RAD50

8.72e-0575484935906200
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MSH6 MKI67 DKC1 GPATCH4 LYAR SPTY2D1 MED12 GTF3C3 NUP205

9.16e-0575984935915203
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MSH6 SETX MKI67 DKC1 GPATCH4 LYAR EPB41L3 MGA MED12 GTF3C3 NUP205 RAD50

9.72e-051353841229467282
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

FLG MSH6 EHMT2 DKC1 GPATCH4 LYAR GTF3C3 RAD50

1.05e-0460184833658012
Pubmed

Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes.

PPARGC1A MYH7 MKI67

1.08e-043884338196272
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SETX WWP2 MKI67 ASCC2 DKC1 GPATCH4 LYAR MECP2 SPTY2D1 GTF3C3 AFF4 NUP205

1.10e-041371841236244648
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

EHMT2 MKI67 DKC1 CWC22

1.17e-0410384432744500
Pubmed

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

NABP2 NABP1

1.20e-04784218449195
Pubmed

An Indispensable Role of Androgen Receptor in Wnt Responsive Cells During Prostate Development, Maturation, and Regeneration.

KRT8 MKI67

1.20e-04784229451339
Pubmed

S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.

GRIP1 PPARGC1A

1.20e-04784217704298
Pubmed

Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation.

EHMT2 MED12

1.20e-04784218691967
Pubmed

Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior.

KRT8 MKI67

1.20e-04784238788809
Pubmed

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.

FLG RAD50

1.20e-04784223886662
InteractionSNRNP40 interactions

SETX SLC4A1AP BAZ2B ZC3H13 MKI67 DKC1 GON4L GPATCH4 SREK1 MGA CWC22 MECP2 SPTY2D1 PRPF18 MED12

4.43e-086378315int:SNRNP40
InteractionHDAC1 interactions

GRIP1 MSH6 MYH7 RAPGEF6 EHMT2 WWP2 MKI67 ASCC2 GON4L AFF1 CRYBG3 EPB41L3 SSX2 MGA MECP2 MED12 USP47 RAD50

4.57e-0711088318int:HDAC1
InteractionNIFK interactions

EHMT2 WWP2 MKI67 DKC1 GPATCH4 SREK1 LYAR MECP2 SPTY2D1 AFF4 NUP205

1.53e-064318311int:NIFK
InteractionNUP43 interactions

SETX BAZ2B ZC3H13 MKI67 DKC1 GON4L GPATCH4 SREK1 RAPGEF2 MGA CWC22 MECP2 MED12

1.56e-066258313int:NUP43
InteractionCOIL interactions

MSH6 EHMT2 BAZ2B MKI67 DKC1 GPATCH4 MGA MECP2 SPTY2D1 GTF3C3 AFF4 NUP205

2.61e-065528312int:COIL
InteractionSMC5 interactions

SETX SLC4A1AP BAZ2B ZC3H13 MKI67 DKC1 GPATCH4 SREK1 LYAR EPB41L3 SSX2 MGA CWC22 MECP2 AFF4 RAD50

2.70e-0610008316int:SMC5
InteractionMECP2 interactions

FLG MSH6 KRT8 DMXL2 SETX ZC3H13 MKI67 DKC1 SREK1 LYAR EPB41L3 CWC22 MECP2 MED12 GTF3C3 AFF4 SACM1L NUP205

3.89e-0612878318int:MECP2
InteractionNLE1 interactions

BAZ2B ZC3H13 MKI67 DKC1 GPATCH4 LYAR MECP2 SPTY2D1

4.52e-06228838int:NLE1
InteractionPOLR1G interactions

SLC4A1AP BAZ2B DKC1 GPATCH4 LYAR MGA MECP2 GTF3C3 AFF4 NUP205 RAD50

5.13e-064898311int:POLR1G
InteractionH3C3 interactions

MSH6 SETX EHMT2 BAZ2B MKI67 GPATCH4 LYAR MGA MECP2 GTF3C3 AFF4

5.76e-064958311int:H3C3
InteractionZNF330 interactions

MSH6 SLC4A1AP DKC1 GPATCH4 LYAR MECP2 SPTY2D1 GTF3C3 AFF4 NUP205

1.46e-054468310int:ZNF330
InteractionH2BC8 interactions

MSH6 SLC4A1AP EHMT2 POLG MKI67 GON4L ZC3HC1 GPATCH4 LYAR MGA MECP2

2.37e-055768311int:H2BC8
InteractionPIP4K2A interactions

PIP5K1A AFF1 LYAR EPB41L3 CWC22 MECP2 AFF4

3.07e-05216837int:PIP4K2A
InteractionSNRNP70 interactions

MSH6 KRT8 ZC3H13 WWP2 MKI67 LRP1 DKC1 PIP5K1A GPATCH4 SREK1 LYAR CWC22 MECP2 GTF3C3

4.53e-059848314int:SNRNP70
InteractionGPATCH4 interactions

WWP2 MKI67 DKC1 GPATCH4 LYAR ADARB2 SPTY2D1

4.83e-05232837int:GPATCH4
InteractionH2AC17 interactions

EHMT2 ASCC2 DKC1 GON4L PIP5K1A GPATCH4 SREK1

4.83e-05232837int:H2AC17
InteractionSIRT6 interactions

MSH6 MYH7 EHMT2 MKI67 ASCC2 DKC1 MED12 GTF3C3 NUP205 ANKS1A RAD50

5.20e-056288311int:SIRT6
InteractionSMC1A interactions

MSH6 NDC80 EHMT2 WWP2 MKI67 MGA MECP2 GTF3C3 RAD50

5.52e-05418839int:SMC1A
InteractionDGCR8 interactions

MSH6 WWP2 DKC1 GPATCH4 SREK1 MECP2 SPTY2D1

6.31e-05242837int:DGCR8
InteractionMED12 interactions

PPARGC1A EHMT2 ZC3H13 MKI67 MECP2 MED12

8.81e-05176836int:MED12
InteractionFGFBP1 interactions

MKI67 DKC1 GPATCH4 SREK1 CWC22 SPTY2D1 GTF3C3

9.20e-05257837int:FGFBP1
InteractionPOLR1E interactions

EHMT2 BAZ2B DKC1 GPATCH4 LYAR MGA GTF3C3 RAD50

9.71e-05350838int:POLR1E
InteractionSSRP1 interactions

MSH6 SETX ZC3H13 WWP2 NABP2 DKC1 SREK1 LYAR MECP2 SPTY2D1 REXO1

1.13e-046858311int:SSRP1
InteractionAFF4 interactions

AFF1 LYAR EPB41L3 MECP2 AFF4

1.13e-04115835int:AFF4
InteractionSLX4 interactions

MSH6 BAZ2B MKI67 GPATCH4 MGA SPTY2D1 REXO1 GTF3C3 AFF4 RAD50

1.19e-045728310int:SLX4
InteractionEPB41L3 interactions

DKC1 AFF1 LYAR EPB41L3 CWC22 MECP2 AFF4

1.31e-04272837int:EPB41L3
InteractionLYAR interactions

WWP2 MKI67 DKC1 GPATCH4 LYAR EPB41L3 MECP2 AFF4

1.50e-04373838int:LYAR
InteractionDDX23 interactions

MSH6 ZC3H13 DKC1 GPATCH4 SREK1 LYAR CWC22 MECP2 AFF4

1.58e-04480839int:DDX23
InteractionAFF1 interactions

MYH7 AFF1 EPB41L3 AFF4

1.59e-0466834int:AFF1
InteractionADARB1 interactions

WWP2 MKI67 DKC1 ZC3HC1 STOX1 LYAR ADARB2 SPTY2D1 RAD50

1.81e-04489839int:ADARB1
InteractionRBBP5 interactions

BAZ2B ZC3H13 MKI67 DKC1 MGA MECP2 PRPF18

1.82e-04287837int:RBBP5
InteractionRCOR1 interactions

MSH6 RAPGEF6 EHMT2 MKI67 EPB41L3 MGA MECP2 MED12 RAD50

1.96e-04494839int:RCOR1
InteractionRNF2 interactions

PPARGC1A EHMT2 WWP2 PCLO MKI67 DKC1 GPATCH4 LYAR SSX2 MGA NUP205 RAD50

2.14e-048668312int:RNF2
InteractionSRSF6 interactions

PPARGC1A ZC3H13 WWP2 MKI67 DKC1 PIP5K1A SREK1 MECP2 SPTY2D1

2.24e-04503839int:SRSF6
InteractionRPS6 interactions

WWP2 PCLO MKI67 ASCC2 DKC1 GPATCH4 SREK1 LYAR MECP2 SPTY2D1 GTF3C3 NUP205

2.33e-048748312int:RPS6
InteractionSRSF4 interactions

PPARGC1A ENOX1 MKI67 DKC1 SREK1 MECP2 GTF3C3

2.39e-04300837int:SRSF4
InteractionUSP53 interactions

MSH6 KRT8 MKI67 GPATCH4 RAD50

2.65e-04138835int:USP53
InteractionAURKB interactions

MSH6 ADRA1D SETX NDC80 MKI67 HEATR5A CRYBG3 LYAR GTF3C3 NUP205 RAD50

2.81e-047618311int:AURKB
InteractionMEN1 interactions

EHMT2 ZC3H13 SETBP1 MKI67 DKC1 ZC3HC1 GPATCH4 SREK1 LYAR MED12 GTF3C3 AFF4 NUP205

2.83e-0410298313int:MEN1
InteractionCWC22 interactions

MKI67 EPB41L3 CWC22 MECP2 PRPF18

2.93e-04141835int:CWC22
InteractionCDK8 interactions

SLC4A1AP EHMT2 MGA MED12 GTF3C3 NUP205

3.11e-04222836int:CDK8
InteractionZBTB38 interactions

MSH6 EHMT2 MGA MECP2 SPTY2D1

3.33e-04145835int:ZBTB38
InteractionCCNT1 interactions

WWP2 MKI67 AFF1 EPB41L3 MECP2 AFF4

3.34e-04225836int:CCNT1
InteractionROGDI interactions

DMXL2 MYH7 MECP2

3.36e-0433833int:ROGDI
InteractionARL4D interactions

EHMT2 MKI67 GPATCH4 MGA SPTY2D1

3.44e-04146835int:ARL4D
InteractionFMR1 interactions

EHMT2 WWP2 MKI67 LRP1 DKC1 GRIP2 RAPGEF2 AFF4 RAD50

3.57e-04536839int:FMR1
InteractionCHAMP1 interactions

EHMT2 MKI67 MGA MECP2 RAD50

3.66e-04148835int:CHAMP1
InteractionARL16 interactions

MKI67 GPATCH4 RAPGEF2 MGA

3.84e-0483834int:ARL16
InteractionASB3 interactions

SLC4A1AP KATNB1 GON4L EPB41L3

4.02e-0484834int:ASB3
InteractionRPF2 interactions

WWP2 MKI67 DKC1 GPATCH4 LYAR MECP2

4.31e-04236836int:RPF2
InteractionTERF2IP interactions

SETX SLC4A1AP MKI67 GPATCH4 SREK1 MGA GTF3C3 AFF4 RAD50

4.42e-04552839int:TERF2IP
InteractionKDM1A interactions

MSH6 RAPGEF6 SLC4A1AP EHMT2 LRP1 ASCC2 CRYBG3 EPB41L3 MGA MED12 GTF3C3 RAD50

4.56e-049418312int:KDM1A
InteractionFGF12 interactions

GRIP1 AFF1 AFF4 USP47

4.59e-0487834int:FGF12
InteractionSSX6P interactions

SSX6P SSX2

4.62e-048832int:SSX6P
InteractionNHLH1 interactions

EHMT2 MKI67 GPATCH4 MGA

4.79e-0488834int:NHLH1
InteractionINTS5 interactions

NABP2 MKI67 NABP1 MECP2 GTF3C3

4.93e-04158835int:INTS5
InteractionCSNK2A1 interactions

FLG MSH6 SLC4A1AP EHMT2 ZC3H13 WWP2 DKC1 SREK1 EPB41L3 MGA MECP2 GTF3C3

5.25e-049568312int:CSNK2A1
InteractionMDK interactions

LRP1 CWC22 MECP2 AFF4

5.44e-0491834int:MDK
InteractionYY1 interactions

PPARGC1A EHMT2 MKI67 GON4L LYAR MGA MECP2 GTF3C3

5.62e-04454838int:YY1
InteractionH2BC21 interactions

PPARGC1A MSH6 EHMT2 WWP2 PCLO NABP2 MKI67 EPB41L3 MECP2 RAD50

5.67e-046968310int:H2BC21
InteractionKLF9 interactions

EHMT2 GON4L GPATCH4 MGA

5.91e-0493834int:KLF9
InteractionMAGEB2 interactions

WWP2 DKC1 PIP5K1A GPATCH4 SREK1 LYAR SPTY2D1

5.91e-04349837int:MAGEB2
InteractionTATDN3 interactions

MSH6 RAD50

5.92e-049832int:TATDN3
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PCLO ZC3HC1 LYAR

1.54e-051560326
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF1 AFF4

6.47e-0546021145
GeneFamilyPDZ domain containing

GRIP1 RAPGEF6 PCLO GRIP2 RAPGEF2

1.48e-041526051220
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF1 AFF4

3.84e-0496021280
GeneFamilyZinc fingers CXXC-type|Methyl-CpG binding domain containing

BAZ2B MECP2

5.84e-04116021025
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

PPARGC1A RAPGEF6 SETX SLC30A5 NDC80 SLC4A1AP BAZ2B PLXNC1 MKI67 SREK1 EPB41L3 USP47 SACM1L RAD50

1.51e-086568214M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

MSH6 DMXL2 SETX NDC80 BAZ2B PIP5K1A AFF1 CRYBG3 RAPGEF2 MECP2 DENND2B ANKS1A

1.38e-058568212M4500
CoexpressionGSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP

RAPGEF6 BAZ2B GPATCH4 MGA NPEPL1 RAD50

1.64e-05171826M2947
CoexpressionWANG_LMO4_TARGETS_DN

SLC4A1AP BAZ2B DKC1 PIP5K1A GPATCH4 GTF3C3 AFF4 USP47

1.76e-05361828M12674
CoexpressionHONRADO_BREAST_CANCER_BRCA1_VS_BRCA2

KRT8 MKI67 RAD50

1.94e-0517823M9940
CoexpressionGSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP

PLXNC1 BLOC1S5 LYAR SPTY2D1 MED12 USP47

3.85e-05199826M9491
CoexpressionGSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN

SETX BLOC1S5 ZNF398 MGA MECP2 AFF4

3.85e-05199826M6030
CoexpressionGSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN

MSH6 SLC30A5 BAZ2B GRAMD2B LRP1 RAD50

3.96e-05200826M8648
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

GRIP1 PPARGC1A DMXL2 SLC4A1AP PLXNC1 PCLO SETBP1 MKI67 GON4L LYAR MECP2 AFF4 RAD50

9.64e-068317813Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_500

KRT8 SCUBE1 PLXNC1 DENND2B

2.90e-0548784gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

MSH6 DMXL2 SETX DKC1 HEATR5A NABP1 LYAR ZW10 CWC22 GTF3C3 NUP205 RAD50

3.13e-057957812gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500

PPARGC1A SCUBE1 ENOX1 PLXNC1 PCLO SETBP1 LYAR SRRM3 CWC22

8.03e-05493789Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

MSH6 SETX NDC80 PLXNC1 POLG PCLO GPATCH4 HEATR5A LYAR

1.43e-04532789Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#5

GRIP1 SCUBE1 PCLO OSBPL7 CWC22 MECP2

1.63e-04221786Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K5
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

AFF1 HEATR5A CRYBG3 MGA SPTY2D1 GTF3C3

1.77e-06193846abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPARGC1A KATNB1 OSBPL7 ZC3HC1 SPTY2D1

1.20e-05157845bd45590da540a557dc8096980a45220fccb99505
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPARGC1A KATNB1 OSBPL7 ZC3HC1 SPTY2D1

1.20e-0515784500c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETBP1 MKI67 GON4L NABP1 USP47

1.92e-05173845c31076c725f4cd912c56903592a2d9356ae59f54
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETBP1 MKI67 GON4L NABP1 USP47

1.92e-05173845a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

DMXL2 GON4L MGA SACM1L RAD50

2.57e-05184845ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THEMIS2 DMXL2 AFF1 NABP1 EPB41L3

2.85e-051888453be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

SETBP1 ZNF398 HEATR5A GTF3C3 NUP205

2.85e-051888458f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SETBP1 ZNF398 HEATR5A GTF3C3 NUP205

2.93e-05189845c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

PPARGC1A MYH7 ENOX1 MYOM3 GRIP2

3.00e-05190845de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

PPARGC1A MYH7 ENOX1 MYOM3 GRIP2

3.08e-0519184525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SETBP1 ZNF398 HEATR5A GTF3C3 NUP205

3.16e-05192845445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCellHSPCs-Ery_prog.|World / Lineage and Cell class

PLXNC1 DKC1 GPATCH4 LYAR NPEPL1

3.23e-05193845484c2e0daedc6cb0d50d164add8c1658123a60f9
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THEMIS2 DMXL2 SLC24A4 PLXNC1 EPB41L3

3.32e-05194845de9c7c602d886d0cd8bbd1d7e7744f84df951238
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THEMIS2 DMXL2 SLC24A4 PLXNC1 EPB41L3

3.32e-0519484549441ca0a8fa34cb847fecbb4b809dd01d879ebb
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

DMXL2 SLC24A4 PLXNC1 LRP1 EPB41L3

3.48e-05196845256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

THEMIS2 DMXL2 PLXNC1 LRP1 EPB41L3

3.48e-051968457026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEMIS2 GRIP1 DMXL2 NABP1 EPB41L3

3.57e-0519784510190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

THEMIS2 DMXL2 SLC24A4 PLXNC1 EPB41L3

3.57e-051978453896729740d151f0eb845f1961c7b969bfbdd28d
ToppCellCOVID-19_Moderate-Classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

THEMIS2 DMXL2 SLC24A4 LRP1 EPB41L3

3.57e-0519784598d4107e457e7399a84439acd73bf8f59598971b
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

ZC3H13 GPATCH4 SREK1 LYAR RAD50

3.57e-051978450fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellsevere-HLA-DR+_CD83+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMXL2 SLC24A4 BAZ2B LRP1 NABP1

3.65e-05198845a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPARGC1A PCLO SETBP1 SLC4A10 SRRM3

3.65e-05198845c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 PCLO SETBP1 SLC4A10 SRRM3

3.65e-051988454ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 PCLO SETBP1 SLC4A10 SRRM3

3.65e-051988450ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THEMIS2 DMXL2 SLC24A4 NABP1 EPB41L3

3.74e-051998455b6feacb0ca92c3fc6b327be978320426dcf6f68
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

THEMIS2 SLC24A4 PLXNC1 HEATR5A EPB41L3

3.74e-051998454e0b73d88b1345ec63a9e5629762341e75beb47f
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

SETX BAZ2B ZC3H13 USP47 RAD50

3.74e-05199845fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellcellseq2-Immune-Immune_Myeloid-IM-IM|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THEMIS2 DMXL2 PLXNC1 LRP1 EPB41L3

3.74e-05199845372fb9eb90022dc4ac770a75b4e207c33d1d0c43
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

POLG KATNB1 OSBPL7 LYAR MECP2

3.74e-0519984526bb93347e6722abd174dfa62cab692ce2b7eb23
ToppCellcellseq2-Immune-Immune_Myeloid-IM|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THEMIS2 DMXL2 PLXNC1 LRP1 EPB41L3

3.74e-05199845dd3bf59cdc18091889cbf6c43f37100ba537843d
ToppCellcellseq2-Immune-Immune_Myeloid|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THEMIS2 DMXL2 PLXNC1 LRP1 EPB41L3

3.74e-051998456c3c9eceea20121ae17ae2462134aa0437f591b3
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THEMIS2 DMXL2 SLC24A4 PLXNC1 LRP1

3.74e-05199845ac866ae110967c5867ff4601939b79861d43df54
ToppCellmild-Non-classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMXL2 SLC24A4 PLXNC1 LRP1 EPB41L3

3.83e-05200845334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THEMIS2 DMXL2 SLC24A4 PLXNC1 LRP1

3.83e-052008455432bdf495431cd26f6e4cd585100f3652588913
ToppCellSigmoid-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

DMXL2 SETX NDC80 MKI67 NUP205

3.83e-05200845372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THEMIS2 DMXL2 SLC24A4 PLXNC1 LRP1

3.83e-052008458872d5fa101d413fb43b4231d476878678543035
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

KRT8 SLC24A4 PCLO CRYBG3

2.38e-04160844731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCellIPF-Epithelial-Ionocyte|IPF / Disease state, Lineage and Cell class

PPARGC1A KRT8 PCLO ADARB2

2.38e-04160844d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

KRT8 SLC24A4 PCLO CRYBG3

2.38e-04160844cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCellIPF-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

PPARGC1A KRT8 PCLO ADARB2

2.44e-04161844f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 STOX1 LYAR REXO1

2.56e-04163844360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 STOX1 LYAR REXO1

2.56e-04163844b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GARIN4 NDC80 MKI67 ADARB2

2.62e-041648444307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GARIN4 NDC80 MKI67 ADARB2

2.62e-041648441d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

SETBP1 ZNF398 HEATR5A NUP205

2.74e-04166844a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell343B-Myeloid-Dendritic-cDC_activated|343B / Donor, Lineage, Cell class and subclass (all cells)

SNHG28 ENOX1 PLXNC1 NABP1

2.93e-041698442098f15a388d019ed7f1d4c209affd5ca2886dcc
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIP1 KRT8 GRAMD2B SRRM3

3.00e-04170844fed8e982d2ce234c59d4016432ed8941df36df27
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADRA1D PLXNC1 LRP1 DENND2B

3.00e-041708445570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GARIN4 DMXL2 LRP1 NABP1

3.07e-041718445e93c76ee60f9d0590ebb140812653a5e1369417
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1_VIP_PCDH20|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA1D GRIP2 NABP1 ADARB2

3.14e-0417284435e961c88bfe79046533396912cedf00ca81db7b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THEMIS2 DMXL2 SLC24A4 NABP1

3.35e-04175844e991ffa4d1d278a011592b9915cd35fe76db20cc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 ADRA1D GRIP2 ADARB2

3.35e-041758440c648e7f67ffbe3b476a2ca77d246554f8cd1882
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 MKI67 LRP1 NABP1

3.42e-04176844270d7908dbd84028958d257f94941dc685e20255
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 MKI67 LRP1 NABP1

3.50e-0417784467cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF6 SETX NDC80 GRAMD2B

3.57e-04178844a9a8567d8fdc0fffd612fee16b5b29ef7b1c9307
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF6 SETX NDC80 GRAMD2B

3.57e-041788445ecbea15efd304057aef826ec2f385997bfaf0c9
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF6 NDC80 GRAMD2B NABP1

3.65e-041798448bf04a7ad1b0be6722ebfdceba3f083f07bf96c5
ToppCellLV|World / Chamber and Cluster_Paper

MYH7 ENOX1 MYOM3 GRIP2

3.72e-041808445ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCUBE1 NDC80 MKI67 OSBPL7

3.72e-0418084440d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 PPARGC1A PLXNC1 GRIP2

3.80e-04181844bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADRA1D ENOX1 GRAMD2B ADARB2

3.80e-04181844451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THEMIS2 DMXL2 NDC80 MKI67

3.88e-0418284421dcab170ffeef89faa9fee5008568cb6e15c694
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ENOX1 SETBP1 CRYBG3 EPB41L3

3.88e-041828447b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THEMIS2 DMXL2 MKI67 NABP1

3.88e-0418284457f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCellControl-APC-like-Dendritic_cells|Control / group, cell type (main and fine annotations)

ENOX1 SLC24A4 PLXNC1 NABP1

3.96e-041838448f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

ENOX1 SLC24A4 PLXNC1 NABP1

3.96e-04183844c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 PCLO MKI67 NUP205

4.05e-0418484416aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMXL2 PCLO MKI67 NUP205

4.13e-04185844b4af9ae4c358b48357cb135b740266e1652d886a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 ADRA1D GRIP2 ADARB2

4.13e-041858444c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

GARIN4 MYH7 MYOM3 GRIP2

4.13e-041858446baccb26f999145e51b91d94315bf8d4655bef31
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF1 SPTY2D1 AFF4 USP47

4.13e-04185844eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KRT8 DMXL2 SLC24A4 EPB41L3

4.22e-04186844f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BAZ2B PCLO LRP1 SREK1

4.22e-0418684423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 ADRA1D GRIP2 ADARB2

4.22e-04186844310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KRT8 DMXL2 SLC24A4 EPB41L3

4.22e-041868448694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

SETX ZC3H13 HEATR5A SPTY2D1

4.22e-0418684403db813598b67b1e08f759758a1c2023396921fa
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

MYH7 ENOX1 MYOM3 GRIP2

4.30e-0418784478cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

GRIP1 PPARGC1A MYOM3 GRIP2

4.39e-041888446d249fe92d51a19da19ec14bb2262d394255d577
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 ADRA1D GRIP2 ADARB2

4.39e-041888440501a8aa850bd2e347020abd1cac4d8075738189
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 ADRA1D GRIP2 ADARB2

4.39e-04188844433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

PPARGC1A MYH7 MYOM3 GRIP2

4.39e-041888440758b474457efa36488e0195f7357100f4b6a090
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7 ADRA1D MYOM3 GRIP2

4.39e-04188844d534ed9870405a3c1075962308f72b460aed17bf
ToppCelldroplet-Marrow-BM-1m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DKC1 GPATCH4 LYAR NPEPL1

4.48e-04189844b81540e097e95158851e07bfd78640ed6e64c2cf
ToppCellControl-Myeloid-Monocytes|Control / group, cell type (main and fine annotations)

THEMIS2 DMXL2 SLC24A4 PLXNC1

4.48e-041898443335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

PPARGC1A ENOX1 MYOM3 GRIP2

4.48e-041898449c1debd65c13d63fd4f3158917d621b44b714c26
ToppCelldroplet-Marrow-BM-1m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DKC1 GPATCH4 LYAR NPEPL1

4.48e-041898440fda1a3f1e87fadf5309c8267beaa4501983b1dd
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

MYH7 ENOX1 MYOM3 GRIP2

4.48e-041898445e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 ADRA1D GRIP2 ADARB2

4.48e-04189844f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellASK452-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

TSEN54 LYAR SACM1L PGBD2

4.48e-04189844f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCell3'_v3-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

THEMIS2 DMXL2 SLC24A4 LRP1

4.48e-0418984474a5e61cd820f2495dde40e766c771a31d8c4e7d
ToppCellcontrol-Myeloid-CD14_Monocytes_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

DMXL2 SLC24A4 LRP1 EPB41L3

4.57e-0419084447513757e0059e8370e49672a577f25ca842e98c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 ADRA1D GRIP2 ADARB2

4.57e-0419084456cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADRA1D ENOX1 ADARB2 DENND2B

4.57e-041908444eb92aef1ee868f4537483d19014d947b7684612
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 DKC1 GPATCH4 RAD50

4.57e-0419084452c59001a079c76249abbaa3141e9e661b83d9a0
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 ADRA1D GRIP2 ADARB2

4.57e-0419084425d4b591f75c26e404a34c42f1742d580af6598d
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADRA1D ENOX1 ADARB2 DENND2B

4.57e-041908447be4341e2909101d756f14031c21e705eb45e69a
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

PPARGC1A MYH7 MYOM3 GRIP2

4.57e-04190844fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

THEMIS2 DMXL2 NABP1 EPB41L3

4.66e-041918443b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

THEMIS2 DMXL2 LRP1 EPB41L3

4.66e-041918449c4acc5f3c2f9c0c5520863bb22f391774372347
Diseasewhite matter hyperintensity measurement

ADRA1D SETBP1 GON4L TSEN54 NPEPL1 CWC22 DENND2B

1.84e-05302807EFO_0005665
DiseaseMental Retardation, Psychosocial

SETBP1 SLC4A10 GON4L TSEN54 MECP2

3.91e-05139805C0025363
DiseaseProfound Mental Retardation

SETBP1 SLC4A10 GON4L TSEN54 MECP2

3.91e-05139805C0020796
DiseaseMental deficiency

SETBP1 SLC4A10 GON4L TSEN54 MECP2

3.91e-05139805C0917816
Diseasediastolic blood pressure, systolic blood pressure

PPARGC1A MSH6 KRT8 ADRA1D PLXNC1 SETBP1 LRP1 AFF1 DENND2B

8.39e-05670809EFO_0006335, EFO_0006336
Diseaseasthma

FLG DMXL2 RAPGEF6 SLC24A4 PLXNC1 OSBPL7 LRP1 HEATR5A RAD50

1.98e-04751809MONDO_0004979
Diseasesevere acute respiratory syndrome, COVID-19

GRIP1 PPARGC1A SCUBE1 SLC24A4 SLC4A10 ADARB2 REXO1

2.14e-04447807EFO_0000694, MONDO_0100096
Diseaseparental longevity

PPARGC1A PCLO SETBP1 ZC3HC1 ZW10 SRRM3 PRPF18

3.91e-04494807EFO_0007796
Diseaseexecutive function measurement

DMXL2 ADRA1D SLC24A4 SLC4A10 RAPGEF2 ADARB2

5.59e-04376806EFO_0009332
DiseasePontoneocerebellar hypoplasia

PCLO TSEN54

8.50e-0416802cv:C1261175
DiseaseMultiple congenital anomalies

SETBP1 AFF4

9.61e-0417802C0000772
Diseasecardiomyopathy (is_implicated_in)

MYH7 POLG

1.20e-0319802DOID:0050700 (is_implicated_in)
DiseaseIntellectual Disability

SETBP1 SLC4A10 GON4L TSEN54 MECP2 GTF3C3

1.37e-03447806C3714756
Diseaseage at menopause

GRIP1 MSH6 POLG MGA MED12

1.40e-03302805EFO_0004704
DiseaseEpilepsy, Cryptogenic

POLG SLC4A10 MECP2

1.46e-0382803C0086237
DiseaseAwakening Epilepsy

POLG SLC4A10 MECP2

1.46e-0382803C0751111
DiseaseAura

POLG SLC4A10 MECP2

1.46e-0382803C0236018
Diseasecomplement factor D measurement

PPARGC1A SLC30A5 CWC22

2.09e-0393803EFO_0020283
Diseasebreast cancer (implicated_via_orthology)

MSH6 RAD50

2.09e-0325802DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KKRDSLGTAGSAHLI

BLOC1S5

21

Q8TDH9
VESHSGRGKTISLSK

CRYBG3

826

Q68DQ2
RIIHAKKTGKRDTSG

BAZ2B

1256

Q9UIF8
DSVDLSRVHKGKSTR

ASCC2

551

Q9H1I8
GKLHRAASRGEVSKV

ANKRD26P1

51

Q6NSI1
LEKETRGATERVHGS

EHMT2

26

Q96KQ7
VVLVDGKTKDHRRSS

ANKS1A

466

Q92625
DAGEGTKRHLSRTIS

DMXL2

1386

Q8TDJ6
SKSPRETGGKRHESS

FLG

141

P20930
GHGSRKESSAVLSRI

DENND2B

271

P78524
SKDPKTEHGSRKRTI

AFF4

821

Q9UHB7
GSLGHKTASASKRVL

SLC24A4

41

Q8NFF2
GVITRTKHGEKVSLS

RAD50

116

Q92878
RGHLRTKIESGEGTV

ADARB2

516

Q9NS39
LGSSGKTIHELEKVR

MYH7

1516

P12883
RGLGSEKHRKEVSDL

NUP205

206

Q92621
SLAGKHGDDLRRTKT

KRT8

291

P05787
SRGHETSGKGLEKTS

MGA

311

Q8IWI9
RTGESRHKTRGDKIA

GARIN4

441

Q8IYT1
SDRTHANGSIKRGSK

LRP1

2111

Q07954
ISGLVKSKSGLSGRH

KATNB1

626

Q9BVA0
GHGKTRSKEVDKLIR

CWC22

721

Q9HCG8
ESRAHTGSSSRGKRK

GPATCH4

406

Q5T3I0
GKHRRLTRKSSTSID

PCLO

1606

Q9Y6V0
RIKITRDSKDHTVSG

PCLO

4496

Q9Y6V0
AAVGVTRHKSKELSR

PLXNC1

961

O60486
HRSGASRRLEKKTVT

NPEPL1

136

Q8NDH3
LQGRKSRGTDLHSKT

POLG

921

P54098
LEKGQHLGSSSRKER

MED12

1451

Q93074
TQTHRETAGDGKSIK

MKI67

2026

P46013
DGTFIREKGKSVRVH

MSH6

116

P52701
IKKIGHRSVDSSGET

PIP5K1A

61

Q99755
SSVLTGGHEERKTKR

PPARGC1A

361

Q9UBK2
DKLKSARDVVTRTGH

HEATR5A

896

Q86XA9
SSKTRDAGRRHVSGK

GON4L

2056

Q3T8J9
VGAGKRKRRHSEVET

LYAR

266

Q9NX58
VISDIKKGSVAHRTG

GRIP1

601

Q9Y3R0
SDIKKGSVAHRTGTL

GRIP2

586

Q9C0E4
VLGKRESKLGSAHSE

GRAMD2B

16

Q96HH9
RILRVEKTGHSGTLD

DKC1

111

O60832
RGRKSPSKEVSHITA

SCUBE1

536

Q8IWY4
KTDFTRTGKRTHLGL

SACM1L

456

Q9NTJ5
RLGSSTDKKDSGRLH

ENOX1

201

Q8TC92
HITKTVKGGISETRI

EPB41L3

1021

Q9Y2J2
ITKGKLHGSIDVRLS

OSBPL7

86

Q9BZF2
TLHIVKRGDGTRGET

PSG3

121

Q16557
KHRGEGERKDIVSSS

MECP2

451

P51608
VKISGDASTKAHRGV

TAS2R14

216

Q9NYV8
GLSKTSGRRVVSHEV

REXO1

881

Q8N1G1
KHRDEGRKTGSQRSS

SRRM3

281

A6NNA2
DRSGTRKGHIVIKAT

RAPGEF6

406

Q8TEU7
GRVTKTKDGHEVRSC

NABP1

31

Q96AH0
QHLEDGDGKRKRSSS

TSEN54

191

Q7Z6J9
RDHGKTVGVVDTRKK

SETX

1311

Q7Z333
ERKGGRSRSHTRSKS

SREK1

186

Q8WXA9
ESVGTKLSKGSGDRH

SPTY2D1

236

Q68D10
EGETSDGVRKSVHKV

GTF3C3

71

Q9Y5Q9
RRVEGKGSRSSSEHK

AFF1

916

P51825
RAKVSSLSHKIRAGG

ADRA1D

511

P25100
RDVIAGRGIHSKVKS

PGBD2

6

Q6P3X8
DHRTDERKTTIKLGS

ZC3HC1

226

Q86WB0
DRTGTRKGHIVIKGT

RAPGEF2

261

Q9Y4G8
RKGHIVIKGTSERLT

RAPGEF2

266

Q9Y4G8
KVTTHELKEGGESIR

WWP2

681

O00308
RADSHKGTSKRLQGS

ZNF197

276

O14709
SSGTTHKRILTGEKP

ZNF735

226

P0CB33
REATKKSRHGLDSIT

SPATA46

151

Q5T0L3
TTSEKIHERSGPKRG

SSX2

146

Q16385
AAEVTRKSHRGLGES

STOX1

261

Q6ZVD7
SSSEKIHERSGPKRG

SSX6P

146

Q7RTT6
HLEGRTGTAEKKLAS

ZNF398

66

Q8TD17
SKQRRHSSEGGVKSS

THEMIS2

561

Q5TEJ8
RGGTRSILKTHFEKE

SLC4A10

26

Q6U841
TGRVTKTKDGHEVRT

NABP2

26

Q9BQ15
RITQEDIKKTHGGSS

USP47

526

Q96K76
RKSKRRSGEGSHLTT

SNHG28

216

P0DPA3
HTASRKLSVDVGGAK

SLC30A5

221

Q8TAD4
KVGSASLSSGRLHKR

SETBP1

1136

Q9Y6X0
VGIHARTGREKIFSK

PRPF18

286

Q99633
SSRGRHREKEDIKIT

ZC3H13

116

Q5T200
RVLHSGSRDREKTKS

ZC3H13

1226

Q5T200
HSGRLEKEDLGTRIS

ZW10

11

O43264
LTSVHGRSSGEKLSR

ZBTB6

401

Q15916
GSTLDGVSRKKLHLR

SLC4A1AP

546

Q9BWU0
HKDKRLESGDRIRTG

MYOM3

1256

Q5VTT5
KAETKLHTSNSGGRR

MZB1

66

Q8WU39
ERKVSLFGKRTSGHG

NDC80

51

O14777