| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | heat shock protein binding | 8.39e-04 | 163 | 23 | 3 | GO:0031072 | |
| GeneOntologyMolecularFunction | GTP binding | 1.01e-03 | 397 | 23 | 4 | GO:0005525 | |
| GeneOntologyMolecularFunction | guanyl ribonucleotide binding | 1.46e-03 | 439 | 23 | 4 | GO:0032561 | |
| GeneOntologyMolecularFunction | guanyl nucleotide binding | 1.46e-03 | 439 | 23 | 4 | GO:0019001 | |
| GeneOntologyMolecularFunction | Hsp90 protein binding | 1.82e-03 | 55 | 23 | 2 | GO:0051879 | |
| GeneOntologyMolecularFunction | Hsp70 protein binding | 2.37e-03 | 63 | 23 | 2 | GO:0030544 | |
| GeneOntologyMolecularFunction | cysteine-type endopeptidase activity | 4.37e-03 | 86 | 23 | 2 | GO:0004197 | |
| GeneOntologyMolecularFunction | GTPase activity | 6.79e-03 | 341 | 23 | 3 | GO:0003924 | |
| GeneOntologyBiologicalProcess | adhesion of symbiont to host | 1.03e-06 | 20 | 21 | 3 | GO:0044406 | |
| GeneOntologyBiologicalProcess | defense response to protozoan | 8.12e-06 | 39 | 21 | 3 | GO:0042832 | |
| GeneOntologyBiologicalProcess | cellular response to interferon-beta | 9.46e-06 | 41 | 21 | 3 | GO:0035458 | |
| GeneOntologyBiologicalProcess | response to protozoan | 1.02e-05 | 42 | 21 | 3 | GO:0001562 | |
| GeneOntologyBiologicalProcess | response to interferon-beta | 1.53e-05 | 48 | 21 | 3 | GO:0035456 | |
| GeneOntologyBiologicalProcess | positive regulation of pyroptotic inflammatory response | 3.54e-05 | 9 | 21 | 2 | GO:0140639 | |
| GeneOntologyBiologicalProcess | cytolysis in another organism | 3.54e-05 | 9 | 21 | 2 | GO:0051715 | |
| GeneOntologyBiologicalProcess | cytolysis | 6.48e-05 | 12 | 21 | 2 | GO:0019835 | |
| GeneOntologyBiologicalProcess | cellular response to type II interferon | 2.03e-04 | 114 | 21 | 3 | GO:0071346 | |
| GeneOntologyBiologicalProcess | response to type II interferon | 3.80e-04 | 141 | 21 | 3 | GO:0034341 | |
| GeneOntologyBiologicalProcess | amine metabolic process | 4.38e-04 | 148 | 21 | 3 | GO:0009308 | |
| GeneOntologyBiologicalProcess | defense response to Gram-positive bacterium | 4.55e-04 | 150 | 21 | 3 | GO:0050830 | |
| GeneOntologyBiologicalProcess | pyroptotic inflammatory response | 8.29e-04 | 42 | 21 | 2 | GO:0070269 | |
| GeneOntologyBiologicalProcess | response to lipopolysaccharide | 1.12e-03 | 464 | 21 | 4 | GO:0032496 | |
| GeneOntologyBiologicalProcess | negative regulation of type I interferon production | 1.37e-03 | 54 | 21 | 2 | GO:0032480 | |
| GeneOntologyBiologicalProcess | response to molecule of bacterial origin | 1.38e-03 | 491 | 21 | 4 | GO:0002237 | |
| GeneOntologyBiologicalProcess | biological process involved in interaction with host | 1.53e-03 | 228 | 21 | 3 | GO:0051701 | |
| GeneOntologyBiologicalProcess | positive regulation of G1/S transition of mitotic cell cycle | 1.92e-03 | 64 | 21 | 2 | GO:1900087 | |
| GeneOntologyCellularComponent | host cell part | 1.74e-08 | 6 | 21 | 3 | GO:0033643 | |
| GeneOntologyCellularComponent | host intracellular part | 1.74e-08 | 6 | 21 | 3 | GO:0033646 | |
| GeneOntologyCellularComponent | host cell cytoplasm part | 1.74e-08 | 6 | 21 | 3 | GO:0033655 | |
| GeneOntologyCellularComponent | host intracellular region | 1.74e-08 | 6 | 21 | 3 | GO:0043656 | |
| GeneOntologyCellularComponent | host cell cytoplasm | 1.74e-08 | 6 | 21 | 3 | GO:0030430 | |
| GeneOntologyCellularComponent | symbiont-containing vacuole | 1.74e-08 | 6 | 21 | 3 | GO:0020003 | |
| GeneOntologyCellularComponent | symbiont-containing vacuole membrane | 1.74e-08 | 6 | 21 | 3 | GO:0020005 | |
| GeneOntologyCellularComponent | host cellular component | 3.94e-07 | 15 | 21 | 3 | GO:0018995 | |
| Domain | GBP_C | 1.95e-07 | 10 | 23 | 3 | PF02841 | |
| Domain | Guanylate-bd_C | 2.67e-07 | 11 | 23 | 3 | IPR003191 | |
| Domain | GBP | 2.67e-07 | 11 | 23 | 3 | PF02263 | |
| Domain | G_GB1_RHD3_dom | 2.67e-07 | 11 | 23 | 3 | IPR030386 | |
| Domain | Guanylate-bd_N | 2.67e-07 | 11 | 23 | 3 | IPR015894 | |
| Domain | G_GB1_RHD3 | 2.67e-07 | 11 | 23 | 3 | PS51715 | |
| Domain | - | 1.22e-02 | 746 | 23 | 4 | 3.40.50.300 | |
| Domain | P-loop_NTPase | 1.88e-02 | 848 | 23 | 4 | IPR027417 | |
| Pathway | REACTOME_INTERFERON_GAMMA_SIGNALING | 6.85e-05 | 98 | 12 | 3 | M965 | |
| Pubmed | In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters. | 1.41e-08 | 8 | 23 | 3 | 16689661 | |
| Pubmed | Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense. | 4.15e-08 | 11 | 23 | 3 | 18025219 | |
| Pubmed | A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection. | 2.43e-07 | 19 | 23 | 3 | 21551061 | |
| Pubmed | 3.33e-07 | 21 | 23 | 3 | 19158679 | ||
| Pubmed | 4.18e-06 | 5 | 23 | 2 | 12396730 | ||
| Pubmed | Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection. | 4.18e-06 | 5 | 23 | 2 | 31964735 | |
| Pubmed | Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. | 1.50e-05 | 9 | 23 | 2 | 24739961 | |
| Pubmed | Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS. | 2.29e-05 | 11 | 23 | 2 | 24715728 | |
| Pubmed | 2.75e-05 | 12 | 23 | 2 | 35906252 | ||
| Pubmed | 1.24e-04 | 25 | 23 | 2 | 35139355 | ||
| Pubmed | 2.75e-04 | 37 | 23 | 2 | 16707424 | ||
| Interaction | SLC16A10 interactions | 9.84e-06 | 37 | 23 | 3 | int:SLC16A10 | |
| Interaction | TMEM104 interactions | 3.47e-05 | 8 | 23 | 2 | int:TMEM104 | |
| Interaction | GBP7 interactions | 3.47e-05 | 8 | 23 | 2 | int:GBP7 | |
| Interaction | GBP6 interactions | 2.11e-04 | 19 | 23 | 2 | int:GBP6 | |
| Cytoband | 1p22.2 | 3.57e-07 | 28 | 23 | 3 | 1p22.2 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1p22 | 4.41e-05 | 137 | 23 | 3 | chr1p22 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr4q31 | 3.05e-03 | 164 | 23 | 2 | chr4q31 | |
| CoexpressionAtlas | kidney_adult_CortVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_100 | 6.16e-07 | 16 | 23 | 3 | gudmap_kidney_adult_CortVasc_Tie2_k4_100 | |
| CoexpressionAtlas | kidney_adult_GlomCapSys_Tie2_k-means-cluster#4_top-relative-expression-ranked_200 | 5.93e-06 | 33 | 23 | 3 | gudmap_kidney_adult_GlomCapSys_Tie2_k4_200 | |
| CoexpressionAtlas | kidney_adult_RenMedVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_200 | 5.93e-06 | 33 | 23 | 3 | gudmap_kidney_adult_RenMedVasc_Tie2_k4_200 | |
| CoexpressionAtlas | kidney_adult_Mesangium_Meis_k-means-cluster#4_top-relative-expression-ranked_100 | 1.12e-05 | 5 | 23 | 2 | gudmap_kidney_adult_Mesangium_Meis_k4_100 | |
| CoexpressionAtlas | kidney_adult_Mesangium_Meis_k-means-cluster#1_top-relative-expression-ranked_200 | 1.53e-05 | 45 | 23 | 3 | gudmap_kidney_adult_Mesangium_Meis_k1_200 | |
| CoexpressionAtlas | kidney_adult_CortVasc_Tie2_top-relative-expression-ranked_100 | 7.71e-05 | 77 | 23 | 3 | gudmap_kidney_adult_CortVasc_Tie2_100 | |
| CoexpressionAtlas | kidney_adult_GlomCapSys_Tie2_k-means-cluster#3_top-relative-expression-ranked_500 | 1.11e-04 | 87 | 23 | 3 | gudmap_kidney_adult_GlomCapSys_Tie2_k3_500 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#2_top-relative-expression-ranked_1000 | 2.05e-04 | 107 | 23 | 3 | gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000_k2 | |
| CoexpressionAtlas | Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_1000 | 5.15e-04 | 990 | 23 | 6 | PCBC_ECTO_1000 | |
| CoexpressionAtlas | kidney_adult_CortVasc_Tie2_top-relative-expression-ranked_200 | 6.90e-04 | 162 | 23 | 3 | gudmap_kidney_adult_CortVasc_Tie2_200 | |
| CoexpressionAtlas | kidney_adult_Mesangium_Meis_top-relative-expression-ranked_200 | 7.54e-04 | 167 | 23 | 3 | gudmap_kidney_adult_Mesangium_Meis_200 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_1000 | 7.67e-04 | 168 | 23 | 3 | DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_1000 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#1_top-relative-expression-ranked_500 | 8.12e-04 | 39 | 23 | 2 | gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k1 | |
| CoexpressionAtlas | kidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_200 | 8.21e-04 | 172 | 23 | 3 | gudmap_kidney_adult_RenMedVasc_Tie2_200 | |
| CoexpressionAtlas | kidney_adult_GlomCapSys_Tie2_top-relative-expression-ranked_200 | 8.35e-04 | 173 | 23 | 3 | gudmap_kidney_adult_GlomCapSys_Tie2_200 | |
| Drug | Ivermectin | 2.37e-06 | 95 | 23 | 4 | ctd:D007559 | |
| Disease | serum metabolite measurement | 3.36e-03 | 945 | 20 | 4 | EFO_0005653 | |
| Disease | parental longevity | 4.30e-03 | 494 | 20 | 3 | EFO_0007796 | |
| Disease | lung adenocarcinoma | 6.13e-03 | 174 | 20 | 2 | EFO_0000571 | |
| Disease | diffuse plaque measurement | 1.39e-02 | 758 | 20 | 3 | EFO_0010699 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| PGPWGWPLIGHMLTL | 41 | P04798 | |
| PHPPGLPKADPGHWW | 41 | Q9H3Y8 | |
| EWPHWPGHLRGELMP | 751 | O75808 | |
| MAPWPPKGLVPAMLW | 1 | Q96HD1 | |
| MGDTWAQLPWPGPPH | 1 | Q6ZSA7 | |
| KAPTMPKPQWHPPWK | 181 | O43660 | |
| KGIWMWCVPHPKKPG | 76 | P32455 | |
| KGIWMWCVPHPSKPN | 76 | Q6ZN66 | |
| KGIWMWCVPHPSKPN | 76 | Q8N8V2 | |
| VSFPWMRGPAPWPGP | 101 | B1AJZ9 | |
| PPGPWRWKGARGQEP | 116 | O15354 | |
| WVPGHWLPPGFSMPP | 176 | Q8IXT2 | |
| LGGWLPRPWGRRKPM | 6 | O95873 | |
| PWAEMRGPHPPWTEV | 636 | Q96PV7 | |
| KPPPAHPLWRWQMGG | 346 | A6NHQ4 | |
| HPLWRWQMGGPAVPE | 351 | A6NHQ4 | |
| MRPGAPGPLWPLPWG | 1 | O95633 | |
| PRSAAQWPMPHIPWP | 181 | Q9Y586 | |
| QWPMPHIPWPGPNRV | 186 | Q9Y586 | |
| KSPPGMWQRGMWQPG | 431 | Q86VE3 | |
| IHWPMGFKPPHPEWI | 101 | Q96JD6 | |
| PARWMPPRWAQGAPE | 191 | Q86TL0 | |
| PPPWVWMVPGSAGLL | 36 | Q5VWI1 | |
| WHIPGLWHGAPPMAA | 876 | Q8TCY9 | |
| PPKIAWPMKFGSPDW | 141 | Q8TCI5 | |
| PPEPPEGGWGWLVML | 61 | Q8TF71 |