Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	-	PODNL1 LRGUK NLRX1 LRCH4 LINGO2 FBXO33 PRAME LRRC18	1.16e-04	321	86	8	3.80.10.10
Domain	REJ	PKD1L1 PKD1L2	1.25e-04	4	86	2	PS51111
Domain	REJ_dom	PKD1L1 PKD1L2	1.25e-04	4	86	2	IPR014010
Domain	L_dom-like	PODNL1 LRGUK NLRX1 LRCH4 LINGO2 FBXO33 PRAME LRRC18	1.34e-04	328	86	8	IPR032675
Domain	Leu-rich_rpt	PODNL1 LRGUK NLRX1 LRCH4 LINGO2 PRAME LRRC18	2.54e-04	271	86	7	IPR001611
Domain	PKD/REJ-like	PKD1L1 PKD1L2	3.11e-04	6	86	2	IPR002859
Domain	REJ	PKD1L1 PKD1L2	3.11e-04	6	86	2	PF02010
Domain	LRR_1	PODNL1 LRGUK LRCH4 LINGO2 PRAME LRRC18	5.23e-04	219	86	6	PF00560
Pubmed	Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.	GLRA3 AUTS2 RORB TSHZ1 TBR1	3.82e-06	88	92	5	21491433
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CCDC88C CNNM4 HAUS6 ATP2C1 UACA KIAA0586 ZDHHC5 ANKRD26 GRIN3A	6.59e-06	493	92	9	15368895
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	HAUS6 ZDHHC5 APC ANKRD26 TMEM131 TRIM13 C6orf132	6.62e-06	263	92	7	34702444
Pubmed	Polycystin-1L2 is a novel G-protein-binding protein.	PKD1L1 PKD1L2	6.92e-06	2	92	2	15203210
Pubmed	Isolation and expression of Napor/CUG-BP2 in embryo development.	CELF1 CELF2	6.92e-06	2	92	2	12763013
Pubmed	Expression of a dominant negative CELF protein in vivo leads to altered muscle organization, fiber size, and subtype.	CELF1 CELF2	6.92e-06	2	92	2	21541285
Pubmed	Binding of alpha2ML1 to the low density lipoprotein receptor-related protein 1 (LRP1) reveals a new role for LRP1 in the human epidermis.	A2ML1 LRP1	6.92e-06	2	92	2	18648652
Pubmed	Diversity and conservation of CELF1 and CELF2 RNA and protein expression patterns during embryonic development.	CELF1 CELF2	6.92e-06	2	92	2	23468433
Pubmed	NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation.	NLRX1 APC	6.92e-06	2	92	2	26971996
Pubmed	The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.	NLRX1 APC	6.92e-06	2	92	2	26971998
Pubmed	Expression of LRP Gene in Breast Cancer Patients Correlated with MRP1 as Two Independent Predictive Biomarkers in Breast Cancer.	ABCC1 LRP1	6.92e-06	2	92	2	30486550
Pubmed	Atm is a negative regulator of intestinal neoplasia.	APC ATM	6.92e-06	2	92	2	17700532
Pubmed	Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.	CNNM4 APC	6.92e-06	2	92	2	25347473
Pubmed	Phospholipase Cepsilon promotes intestinal tumorigenesis of Apc(Min/+) mice through augmentation of inflammation and angiogenesis.	APC PLCE1	6.92e-06	2	92	2	19458037
Pubmed	Kaiso overexpression promotes intestinal inflammation and potentiates intestinal tumorigenesis in Apc(Min/+) mice.	ZBTB33 APC	2.07e-05	3	92	2	26073433
Pubmed	Impact of Escherichia coli K12 and O18:K1 on human platelets: Differential effects on platelet activation, RNAs and proteins.	ATP2C1 LRCH4	2.07e-05	3	92	2	30385858
Pubmed	Multidrug resistance proteins in renal cell carcinoma.	ABCC1 LRP1	2.07e-05	3	92	2	19393132
Pubmed	Direct recording and molecular identification of the calcium channel of primary cilia.	PKD1L1 PKD1L2	2.07e-05	3	92	2	24336289
Pubmed	Development and characterization of multidrug resistant human hepatocarcinoma cell line in nude mice.	ABCC1 LRP1	2.07e-05	3	92	2	17075973
Pubmed	Effects of Alzheimer's disease on different cortical layers: the role of intrinsic differences in Abeta susceptibility.	RORB TBR1	2.07e-05	3	92	2	17687027
Pubmed	Kaiso-deficient mice show resistance to intestinal cancer.	ZBTB33 APC	2.07e-05	3	92	2	16354691
Pubmed	Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.	LRP1 PLCE1	2.07e-05	3	92	2	27322543
Pubmed	Epigenetic Regulation of Dlg1, via Kaiso, Alters Mitotic Spindle Polarity and Promotes Intestinal Tumorigenesis.	ZBTB33 APC	2.07e-05	3	92	2	30552232
Pubmed	Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in Apc(Min)/+ mice.	APC ATM	2.07e-05	3	92	2	11181458
Pubmed	Pax6 is required at the telencephalic pallial-subpallial boundary for the generation of neuronal diversity in the postnatal limbic system.	APC TSHZ1 TBR1	2.66e-05	22	92	3	21471366
Pubmed	Molecular analysis of the human and mouse alpha 2M family.	A2ML1 LRP1	4.14e-05	4	92	2	7524394
Pubmed	Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle.	APC ATM	4.14e-05	4	92	2	11943150
Pubmed	FLT3-ITD and MLL-PTD influence the expression of MDR-1, MRP-1, and BCRP mRNA but not LRP mRNA assessed with RQ-PCR method in adult acute myeloid leukemia.	ABCC1 LRP1	4.14e-05	4	92	2	24030729
Pubmed	Association between single nucleotide polymorphisms of drug resistance-associated genes and response to chemotherapy in advanced ovarian cancer.	ABCC1 LRP1	4.14e-05	4	92	2	16821592
Pubmed	Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.	AUTS2 RORB TBR1	6.23e-05	29	92	3	20615956
Pubmed	Distribution of mRNA coding for alpha-2-macroglobulin, the murinoglobulins, the alpha-2-macroglobulin receptor and the alpha-2-macroglobulin receptor associated protein during mouse embryogenesis and in adult tissues.	A2ML1 LRP1	6.89e-05	5	92	2	7514554
Pubmed	Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development.	CELF1 CELF2	6.89e-05	5	92	2	15830352
Pubmed	Neuropilin-1 expression in cancer and development.	PLVAP APC	6.89e-05	5	92	2	22025255
Pubmed	MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM.	MCAM APC	6.89e-05	5	92	2	31690663
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	UACA AUTS2 LINGO2 CSMD1 IL7R TG	7.62e-05	265	92	6	19240061
Pubmed	ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.	GPS2 ANKRD26	1.03e-04	6	92	2	22666460
Pubmed	The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing.	CELF1 CELF2	1.03e-04	6	92	2	11158314
Pubmed	MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1.	CELF1 CELF2	1.03e-04	6	92	2	19720736
Pubmed	A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.	CELF1 CELF2	1.03e-04	6	92	2	10893231
Pubmed	A comparative transcript map and candidates for mutant phenotypes in the Tyrp1 (brown) deletion complex homologous to human 9p21-23.	LURAP1L RORB	1.03e-04	6	92	2	10602994
Pubmed	The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.	AUTS2 RORB TSHZ1 TBR1	1.17e-04	94	92	4	23431145
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	HAUS6 CELF1 CELF2 UACA APC ANKRD26 CCAR1 TMEM131 LSM14B	1.30e-04	724	92	9	36232890
Pubmed	Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala.	APC TSHZ1 TBR1	1.41e-04	38	92	3	38086370
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ABCC1 ZBTB33 CENPE LRCH4 APC TMEM131 LMNB2 TRIM13 IQCG	1.43e-04	733	92	9	34672954
Pubmed	Expression analysis of an evolutionarily conserved metallophosphodiesterase gene, Mpped1, in the normal and beta-catenin-deficient malformed dorsal telencephalon.	RORB TBR1	1.44e-04	7	92	2	20503375
Pubmed	Phospholipase Cϵ Activates Nuclear Factor-κB Signaling by Causing Cytoplasmic Localization of Ribosomal S6 Kinase and Facilitating Its Phosphorylation of Inhibitor κB in Colon Epithelial Cells.	APC PLCE1	1.44e-04	7	92	2	27053111
Pubmed	Expression of mouse alpha-macroglobulins, lipoprotein receptor-related protein, LDL receptor, apolipoprotein E, and lipoprotein lipase in pregnancy.	A2ML1 LRP1	1.44e-04	7	92	2	7595098
Pubmed	Glycine receptors support excitatory neurotransmitter release in developing mouse visual cortex.	GLRA3 GRIN3A	1.44e-04	7	92	2	22988142
Pubmed	miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification.	CELF1 CELF2	1.44e-04	7	92	2	27512039
Pubmed	Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons.	RORB TBR1	1.92e-04	8	92	2	34188164
Pubmed	Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System.	LRP1 APC	1.92e-04	8	92	2	27280679
Pubmed	Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.	ABI2 LRRC18	1.92e-04	8	92	2	17903303
Pubmed	Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators.	CELF1 CELF2	2.46e-04	9	92	2	28763438
Pubmed	A network of genetic repression and derepression specifies projection fates in the developing neocortex.	AUTS2 TBR1	2.46e-04	9	92	2	23144223
Pubmed	Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis.	APC ATM	2.46e-04	9	92	2	22555459
Pubmed	Targeted inactivation of the mouse alpha 2-macroglobulin gene.	A2ML1 LRP1	2.46e-04	9	92	2	7544347
Pubmed	Identification of DeltaNp63alpha protein interactions by mass spectrometry.	ZNF676 UACA CENPE	2.84e-04	48	92	3	20085233
Pubmed	Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.	PKD1L1 PKD1L2	3.07e-04	10	92	2	16805797
Pubmed	Early neocortical regionalization in the absence of thalamic innervation.	RORB TBR1	3.07e-04	10	92	2	10436162
Pubmed	Glycine receptors control the generation of projection neurons in the developing cerebral cortex.	RORB TBR1	3.07e-04	10	92	2	24926615
Pubmed	Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas.	RORB TBR1	3.07e-04	10	92	2	26705332
Pubmed	COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas.	RORB TBR1	3.75e-04	11	92	2	17828260
Pubmed	SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse.	APC TBR1	3.75e-04	11	92	2	24243579
Pubmed	Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner.	PLVAP IL7R	3.75e-04	11	92	2	18403646
Pubmed	The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex.	APC TBR1	3.75e-04	11	92	2	19146812
Pubmed	ApoER2 Controls Not Only Neuronal Migration in the Intermediate Zone But Also Termination of Migration in the Developing Cerebral Cortex.	RORB TBR1	3.75e-04	11	92	2	27909010
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CCDC88C HAUS6 CENPE ABI2 CEP250 PKD1L1 APC ANKRD26 TMEM131	4.35e-04	853	92	9	28718761
Pubmed	Ulk4 Regulates Neural Stem Cell Pool.	APC TBR1	4.49e-04	12	92	2	27300315
Pubmed	Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.	APC TBR1	4.49e-04	12	92	2	19150975
Pubmed	Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.	CSMD1 SEZ6L	4.49e-04	12	92	2	21901158
Pubmed	The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis.	RORB TBR1	4.49e-04	12	92	2	37139782
Pubmed	Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase.	PLVAP IL7R	4.49e-04	12	92	2	20208005
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	CNNM4 HAUS6 DENND4A NLRX1 LRP1 PRMT3 TBR1 POMK	4.78e-04	686	92	8	28380382
Pubmed	N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso.	ZBTB33 GPS2	5.30e-04	13	92	2	14527417
Pubmed	Dystroglycan on radial glia end feet is required for pial basement membrane integrity and columnar organization of the developing cerebral cortex.	RORB TBR1	5.30e-04	13	92	2	23147502
Pubmed	SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons.	RORB TBR1	5.30e-04	13	92	2	18840685
Pubmed	Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities.	RORB TBR1	5.30e-04	13	92	2	30705426
Pubmed	Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF.	RORB TBR1	5.30e-04	13	92	2	35289744
Pubmed	Emx1 and Emx2 cooperate to regulate cortical size, lamination, neuronal differentiation, development of cortical efferents, and thalamocortical pathfinding.	RORB TBR1	5.30e-04	13	92	2	12561075
Pubmed	STAT5 is required for thymopoiesis in a development stage-specific manner.	TRGC2 IL7R	5.30e-04	13	92	2	15294943
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RANBP17 CNNM4 ATP2C1 UACA ANKAR LRP1 AUTS2 CCAR1 CSMD1 PLEKHM1 ZNF461 NPAS2	5.55e-04	1489	92	12	28611215
Pubmed	Neurocalcin Delta Knockout Impairs Adult Neurogenesis Whereas Half Reduction Is Not Pathological.	APC TBR1	6.17e-04	14	92	2	30853885
Pubmed	LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.	PLVAP IL7R	6.17e-04	14	92	2	19380791
Pubmed	Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions.	CELF1 CELF2	6.17e-04	14	92	2	28826478
Pubmed	TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology.	AUTS2 TBR1	6.17e-04	14	92	2	27979975
Pubmed	Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells.	LMNB2 TBR1	6.17e-04	14	92	2	22116031
Pubmed	Differential regulation of telencephalic pallial-subpallial boundary patterning by Pax6 and Gsh2.	TSHZ1 TBR1	6.17e-04	14	92	2	18701439
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	HAUS6 CEP250 KIAA0586 ANKRD26	6.25e-04	146	92	4	21399614
Pubmed	The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals.	AUTS2 RORB TBR1	6.34e-04	63	92	3	22923088
Pubmed	Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.	ATM TBR1	7.11e-04	15	92	2	26290337
Pubmed	A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse.	RORB TBR1	7.11e-04	15	92	2	23727838
Pubmed	Retinoic acid controls early neurogenesis in the developing mouse cerebral cortex.	RORB TBR1	7.11e-04	15	92	2	28790015
Pubmed	SOX5 controls the sequential generation of distinct corticofugal neuron subtypes.	RORB TBR1	7.11e-04	15	92	2	18215621
Pubmed	Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation.	RORB TBR1	7.11e-04	15	92	2	22951639
Pubmed	Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.	ATM TBR1	7.11e-04	15	92	2	27073218
Pubmed	Role for Lhx2 in corticogenesis through regulation of progenitor differentiation.	RORB TBR1	7.11e-04	15	92	2	23454273
Pubmed	Tuba8 Drives Differentiation of Cortical Radial Glia into Apical Intermediate Progenitors by Tuning Modifications of Tubulin C Termini.	RORB TBR1	7.11e-04	15	92	2	32097653
Pubmed	Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex.	RORB TBR1	7.11e-04	15	92	2	18255031
Pubmed	Heterogeneous nuclear ribonucleoprotein A3 controls mitotic progression of neural progenitors via interaction with cohesin.	ATM TBR1	8.11e-04	16	92	2	32321712
Pubmed	Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology.	AUTS2 TBR1	8.11e-04	16	92	2	19948250
ToppCell	droplet-Marrow-BM-1m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP17 GVINP1 LRP1 AUTS2 PKD1L2 C6orf132	1.35e-06	168	92	6	2e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 PODNL1 ATM SEMA4A IL7R	1.11e-05	141	92	5	d3ce2218bfa9750795d920e1ef162ea44efb2e66
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CNNM4 PLBD1 LRGUK ZBTB33 LMNB2	1.65e-05	153	92	5	489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VSIG2 KRT20 RORB LINGO2 TBR1	1.99e-05	159	92	5	a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 PODNL1 ANKAR SEMA4A IL7R	1.99e-05	159	92	5	5c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK1 SLC17A3 ANKAR PKHD1 GBP1	2.17e-05	162	92	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	ICU-SEP-Lymphocyte-T_NK-MAIT\|ICU-SEP / Disease, Lineage and Cell Type	ZNF10 RANBP17 TRGC2 AUTS2 IL7R	2.30e-05	164	92	5	db863a44fc0dad5518c47fdbf64ea21d6f36f089
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 GRIN3A SEMA4A TBR1 IL7R	2.37e-05	165	92	5	eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 PODNL1 CENPE SEMA4A IL7R	2.74e-05	170	92	5	6b91d4cbe0697b65bfb2e099e7a9b39ea2fba3a9
ToppCell	facs-Lung-Endomucin-24m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAUS6 PRMT3 LMNB2 PKD1L2 TG	3.06e-05	174	92	5	7565f6d1c743809807d248ab0e098a2474d9c5b9
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PHEX PODNL1 CELF2 GLRA3 LRP1	3.06e-05	174	92	5	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CNNM4 CENPE LRP1 KLF18 SEMA4A	3.32e-05	177	92	5	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	UACA TRGC2 LMNB2 PLEKHM1 C6orf132	3.60e-05	180	92	5	12f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	UACA TRGC2 LMNB2 PLEKHM1 C6orf132	3.60e-05	180	92	5	1bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	UACA TRGC2 LMNB2 PLEKHM1 C6orf132	3.60e-05	180	92	5	2a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OR2W3 CENPE RORB LINGO2 LMNB2	4.10e-05	185	92	5	282b3de8850f3c21704339e8d8737b432a43441a
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PKHD1 LRP1 MUC16 RORB CSMD1	4.21e-05	186	92	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CELF2 GLRA3 RORB LINGO2 NPAS2	4.31e-05	187	92	5	f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ZNF10 DENND4A ATP2C1 CELF2 TMEM131	4.42e-05	188	92	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CCDC88C ABCC1 CELF2 IL7R TG	4.54e-05	189	92	5	df30478b288084a1bd48f660409dcc784040897c
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DENND4A CELF2 TRGC2 AUTS2 IL7R	4.54e-05	189	92	5	2c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ZNF10 DENND4A CELF2 ATM IL7R	4.89e-05	192	92	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	COVID-19-lung-NK/NKT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC88C CELF2 TRGC2 LINGO2 ATM	5.01e-05	193	92	5	c24b44fcc92fff42ebba6f1aff91c7aaea179e56
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LRGUK NLRX1 MUC16 ZNF461 PLCE1	5.39e-05	196	92	5	7e98380d815fbf6254289ace2af37aac6fef51e8
ToppCell	mLN-T_cell-Th1\|T_cell / Region, Cell class and subclass	TRGC2 GLRA3 MCAM AUTS2 IL7R	5.52e-05	197	92	5	5e39a49dddef04469ff2b615d755ddf6a926e58e
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Thalamus / BrainAtlas - Mouse McCarroll V32	CELF1 AUTS2 RORB NPAS2	5.52e-05	100	92	4	20675fc2ffc5ab63047d38da083b50d470f3db19
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Thalamus / BrainAtlas - Mouse McCarroll V32	CELF1 AUTS2 RORB NPAS2	5.52e-05	100	92	4	1de3895e16f14ff32b901b18ce14d965afaa7e76
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora\|Thalamus / BrainAtlas - Mouse McCarroll V32	CELF1 AUTS2 RORB NPAS2	5.52e-05	100	92	4	ff1bdb511700a041a90034d1d30dfc25f51d6c82
ToppCell	ASK452-Endothelial-Endothelium\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	PLVAP UACA MCAM APOL1 IL7R	5.66e-05	198	92	5	e282769f5fa1765bcce79a0ed9d761bf2e14b012
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNNM4 PLVAP SLC17A3 A2ML1 MCAM	5.66e-05	198	92	5	88b4662be9cc933a402c52673fa5e00fa979c0db
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_CTL\|Leuk-UTI / Disease, condition lineage and cell class	TRGC2 PKD1L1 GLRA3 AUTS2 POMK	5.79e-05	199	92	5	b2609f9d716fdd04f35f0da7f8995d28d7df431d
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-MAIT\|ICU-SEP / Disease, condition lineage and cell class	ZNF10 RANBP17 TRGC2 AUTS2 IL7R	5.79e-05	199	92	5	2f10622319c6146dfed8cfe3844180c1e1d56e94
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-MAIT\|ICU-NoSEP / Disease, condition lineage and cell class	ZNF10 CEP250 ANKAR KIAA0586 IL7R	5.93e-05	200	92	5	4f03b5f4110ed1637ffe17cb6ff309265a3af9a8
Disease	cannabis dependence measurement	PKHD1 CCAR1 LINGO2 PRMT3 CSMD1	4.07e-07	48	92	5	EFO_0008457
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	PCSK1 RANBP17 CELF1 PKHD1 LRP1 AUTS2 RORB LINGO2 PLCE1	2.12e-06	364	92	9	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	motion sickness	CELF2 AUTS2 TSHZ1 LINGO2	1.55e-05	48	92	4	EFO_0006928
Disease	body fat percentage	PCSK1 RANBP17 CELF1 PKHD1 LRP1 AUTS2 RORB LINGO2 PLCE1	2.22e-05	488	92	9	EFO_0007800
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	APC ATM SEMA4A	7.24e-05	26	92	3	C0009405
Disease	response to alcohol	PCSK1 OR2W3 PKHD1 PRMT3	9.08e-05	75	92	4	EFO_0005526
Disease	Hereditary Nonpolyposis Colorectal Cancer	APC ATM SEMA4A	1.01e-04	29	92	3	C1333990
Disease	response to lamotrigine	GRIN3A CSMD1	3.41e-04	9	92	2	EFO_0007661
Disease	uveal melanoma (is_marker_for)	MCAM PRAME	3.41e-04	9	92	2	DOID:6039 (is_marker_for)
Disease	glucagon-like peptide-1 measurement	LMNB2 CSMD1	4.26e-04	10	92	2	EFO_0008465
Disease	telomere length	PCSK1 ZNF676 VSIG2 ATM CSMD1 NPAS2	4.51e-04	313	92	6	EFO_0004505
Disease	Medulloblastoma	APC ATM PRAME	5.17e-04	50	92	3	C0025149
Disease	tea consumption measurement	OR2W3 PKHD1 CUL9 CSMD1	7.24e-04	129	92	4	EFO_0010091
Disease	serum metabolite measurement	ABCC1 CELF1 SLC17A3 PKD1L1 ABCB8 GLRA3 GBP1 LINGO2 PKD1L2 CSMD1	7.28e-04	945	92	10	EFO_0005653
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	PKHD1 CSMD1	7.33e-04	13	92	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	microglial activation measurement	CCDC88C VSIG2 AUTS2	8.40e-04	59	92	3	EFO_0010940
Disease	response to 5-fluorouracil, response to cyclophosphamide, chemotherapy-induced alopecia, response to doxorubicin	VSIG2 CSMD1	8.54e-04	14	92	2	EFO_0005400, GO_0036275, GO_1902518, GO_1902520
Disease	cognitive function measurement, self reported educational attainment	DENND4A PKHD1 AUTS2 FBXO33 PLEKHM1 NPAS2	8.69e-04	355	92	6	EFO_0004784, EFO_0008354
Disease	PROSTATE CANCER, HEREDITARY, 1	HAUS6 TSHZ1 ATM	8.83e-04	60	92	3	C4722327
Disease	reaction time measurement	PLVAP PKHD1 APC AUTS2 CCAR1 TSHZ1 GRIN3A CSMD1	1.05e-03	658	92	8	EFO_0008393
Disease	amygdala volume change measurement	PKD1L1 CSMD1	1.12e-03	16	92	2	EFO_0021490
Disease	Benign neoplasm of stomach	APC ATM	1.27e-03	17	92	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	APC ATM	1.27e-03	17	92	2	C0496905
Disease	Carcinoma in situ of stomach	APC ATM	1.27e-03	17	92	2	C0154060
Disease	cervical artery dissection	LRP1 PLCE1	1.27e-03	17	92	2	EFO_1000059
Disease	Prostate cancer, familial	HAUS6 TSHZ1 ATM	1.32e-03	69	92	3	C2931456
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	ATM SEMA4A	1.59e-03	19	92	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	ATM SEMA4A	1.59e-03	19	92	2	C2936783
Disease	alcohol consumption measurement	RANBP17 CELF1 ABI2 GLRA3 PKHD1 AUTS2 KLF18 LINGO2 FBXO33 CSMD1 NPAS2	1.67e-03	1242	92	11	EFO_0007878
Disease	neuroimaging measurement	CCDC88C ZNF474 CELF1 SLC17A3 ZDHHC5 LRCH4 PKHD1 APC PLCE1 TG	1.83e-03	1069	92	10	EFO_0004346
Disease	Stomach Carcinoma	APC ATM	1.94e-03	21	92	2	C0699791
Disease	neuroticism measurement, cognitive function measurement	CELF2 ZDHHC5 APC AUTS2 CSMD1 NPAS2 TG	1.98e-03	566	92	7	EFO_0007660, EFO_0008354
Disease	platelet reactivity measurement, response to clopidogrel	LINGO2 PLCE1	2.33e-03	23	92	2	EFO_0004985, GO_1903493
Disease	cortical thickness	ZNF474 PKHD1 LRP1 AUTS2 CCAR1 CUL9 TMEM131 PLEKHM1 PLCE1 TG	2.46e-03	1113	92	10	EFO_0004840
Disease	airway responsiveness measurement	LINGO2 CSMD1	2.54e-03	24	92	2	EFO_0006897
Disease	coffee consumption measurement	RANBP17 PKHD1 AUTS2 LINGO2	2.56e-03	182	92	4	EFO_0006781
Disease	brain volume measurement	ZNF474 CELF1 PKHD1 AUTS2 TSHZ1 CCDC144CP PLEKHM1	2.62e-03	595	92	7	EFO_0006930
Disease	physical activity	PKHD1 GRIN3A CSMD1	2.66e-03	88	92	3	EFO_0003940
Disease	Acute kidney injury	GBP1 LINGO2	2.75e-03	25	92	2	HP_0001919
Disease	triacylglycerol 48:0 measurement	RORB CSMD1	2.98e-03	26	92	2	EFO_0010403
Disease	psychosis predisposition measurement	ABCC1 CSMD1	2.98e-03	26	92	2	EFO_0008337
Disease	migraine disorder, pulse pressure measurement	LRP1 PLCE1	2.98e-03	26	92	2	EFO_0005763, MONDO_0005277
Disease	cortical surface area measurement	CCDC88C ZNF474 CELF2 PKHD1 APC AUTS2 CCAR1 CUL9 PLEKHM1 PLCE1 TG	3.09e-03	1345	92	11	EFO_0010736

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTPQYLALLQQATSS	CELF2	246	O95319
LYSQSLLQQQSAAGS	CELF2	401	O95319
TVPALLNSTSNQLYL	CSMD1	1876	Q96PZ7
IYTQQTALAAAGLTT	CCAR1	41	Q8IX12
YLQLLQQTASSGNLN	CELF1	231	Q92879
SYTALTSITAQIQNG	GVINP1	496	Q7Z2Y8
SDLTTLTSAAYQQSL	GPS2	106	Q13227
NSATSTTNLYTQALL	A2ML1	1126	A8K2U0
TLTETILQYSGQLNN	CCDC144CP	686	Q8IYA2
TLTQTISQYNGRLSV	ANKRD26	966	Q9UPS8
TTYQSKGQTLTLTQQ	ATP2C1	491	P98194
QSLASVAYLINTLAN	ABI2	56	Q9NYB9
LQDSATYNSLLQALS	IQCG	186	Q9H095
LSYQNSSSIVRLTGT	DENND4A	956	Q7Z401
LEQGTTSYAQLLAAT	RANBP17	51	Q9H2T7
NGNVLYSIRLTLTLS	GLRA3	156	O75311
VSINSNTGVLYALQS	PCDHGA11	506	Q9Y5H2
GNLTALTYLNLSRNQ	LRCH4	111	O75427
QDSLLLSTYSQQPGT	NPAS2	776	Q99743
SLYSVQTSTIVLTGN	ANKAR	1221	Q7Z5J8
TLTLNFTISNLQYSP	MUC16	14076	Q8WXI7
LNSGYITATALLTLS	SLC17A3	311	O00476
NTQATNLYGLALSLA	OR52W1	196	Q6IF63
LISATDIQYSGSLLN	ZBTB33	6	Q86T24
SLSYQLSGLQKQASA	LMNB2	316	Q03252
SQNILATYLSGAQVS	LRP1	206	Q07954
LAASSLLSQQYAASL	LSM14B	126	Q9BX40
SSQSAALTAQYTLLQ	CCDC88C	1126	Q9P219
ISVLQQQGSLSNTYL	FBXO33	211	Q7Z6M2
YSQLLGLTASQSNLT	PLVAP	71	Q9BX97
LSFTTSSIPQLLYNL	OR2W3	71	Q7Z3T1
LSAYNSSSLSLNSLS	AUTS2	391	Q8WXX7
TSLLYLNVSNNRLTS	LRRC18	96	Q8N456
LYGLNLTSLSVTNTN	LINGO2	246	Q7L985
LLSSTFVYNSIGTIN	GBP1	121	P32455
YQDLLLSLGTTNSTL	IL7R	401	P16871
KGSSNIASSYLLQQL	LRGUK	51	Q96M69
GQTLTSIYTSFLRLN	NLRX1	391	Q86UT6
YSSQLANLQSLLSSL	KRT20	321	P35900
YILSSGLILLQTTNS	PLBD1	291	Q6P4A8
LLQSNTSTLLLNSSF	PKD1L2	726	Q7Z442
NLTSGQYLSRFLANT	GRIN3A	426	Q8TCU5
AIATLSLSNNQLSYL	PODNL1	196	Q6PEZ8
TSSLVNGNLRLYSSV	C6orf132	111	Q5T0Z8
GLSEQLLNNYSSEIT	ATM	696	Q13315
TVTLTLNNSTQTYGL	PRMT3	516	O60678
QLASLYSALQQALGS	CEP250	1181	Q9BV73
NISNFLSLAGNTYQL	APOL1	261	O14791
SLLESQSTSLRGSYN	LURAP1L	151	Q8IV03
SSVLSLVNQYALDGT	HAUS6	256	Q7Z4H7
SQLLSSLNLLLSAYS	KANK4	601	Q5T7N3
ALYRGQITTSTSNQT	KLF18	806	A0A0U1RQI7
QLDSILSNYTRSGSL	BEND7	296	Q8N7W2
EGSTLNDLLNSQIYT	CUL9	556	Q8IWT3
TLLHYNLQSSVQSLG	PKD1L1	1471	Q8TDX9
YQTLKTSLASGAQVN	CENPE	2346	Q02224
SQNLSTHLLILYGVQ	ABCB8	191	Q9NUT2
QSSQTVESSGLYTLQ	MCAM	191	P43121
AGKQLQRQLSSSSSY	ABCC1	906	P33527
QASLSLHGLNTSTYL	PLEKHM1	336	Q9Y4G2
GQTNKSALLYDSLQT	SEZ6L	511	Q9BYH1
SSGQQNLNTITYETL	CRCP	36	O75575
VITNGAYNSLLSNSS	TBR1	151	Q16650
SQLTTLSFYGNSISI	PRAME	406	P78395
LSFYGNSISISALQS	PRAME	411	P78395
ANDTLLLQLTNTSAY	TRGC2	141	P03986
NISSIGLTYFQSSNL	LIPI	396	Q6XZB0
TLQRTSISQYITGSL	PLCE1	456	Q9P212
ASSTVYNGSLLLIVQ	SEMA4A	601	Q9H3S1
TFSSQLLNLGSYSSI	SHLD2	526	Q86V20
ALITILILYSSNSAN	ST6GALNAC6	51	Q969X2
QSASLLLNESIGANY	PKHD1	3521	P08F94
TLSQYLLTSNFSILA	POMK	211	Q9H5K3
YGANAAIVSSTLSLN	PIGC	166	Q92535
LVGTLTYRSQTNTLA	APC	616	P25054
YSLGNISSNLISFTE	CNNM4	81	Q6P4Q7
YLVNNTQLASSSAAI	ZPLD1	161	Q8TCW7
EGYNKLNQSLTTTQS	ZNF676	96	Q8N7Q3
TSATGINSLQVNYSL	TRIM13	61	O60858
LLQTETTLGLSSYQQ	TMEM131	81	Q92545
RVYSSSISNGLSNLN	RORB	131	Q92753
LLSVYQLSTNGTAQT	NUP188	1366	Q5SRE5
SLLQTLATFRGQYSN	PHEX	186	P78562
LKQALNGLSQLTYTS	UACA	1331	Q9BZF9
GTALVNTSNLIGYQT	ZNF10	551	P21506
NQTRNGSLSYDSLLT	ZDHHC5	461	Q9C0B5
LINQAGLLSSDSYSS	ZNF474	26	Q6S9Z5
QLILTNLSLTSSGTY	VSIG2	201	Q96IQ7
QQILLSGYINSTDTS	TG	101	P01266
TNLSLQNNTIGTYQL	SLC35E3	91	Q7Z769
QAALAKTLQQTSSYG	TSHZ1	201	Q6ZSZ6
GLYLTNLNDSLSSTL	KIAA0586	1251	Q9BVV6
LENYSNLVSLGLSVS	ZNF461	36	Q8TAF7
IYTISISSASQQGLS	PCSK1	326	P29120