Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 NFATC4 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	6.93e-09	1412	36	15	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 NFATC4 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	1.08e-08	1459	36	15	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF202 ZNF444 ZNF536 ZNF227 ZNF160 NFATC4 ZNF665 GLI4 ZNF546 ZNF316 ZNF646	7.42e-06	1244	36	11	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF202 ZNF444 ZNF536 ZNF227 ZNF160 NFATC4 ZNF665 GLI4 ZNF546 ZNF316 ZNF646	9.10e-06	1271	36	11	GO:0000987
GeneOntologyMolecularFunction	MHC class I receptor activity	KIR3DL1 KIR3DS1	4.75e-04	18	36	2	GO:0032393
GeneOntologyMolecularFunction	mitogen-activated protein kinase kinase binding	MAPK8IP1 ACE	5.30e-04	19	36	2	GO:0031434
Domain	-	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	1.12e-11	679	36	14	3.30.160.60
Domain	zf-C2H2	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	1.47e-11	693	36	14	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	1.50e-11	694	36	14	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	6.49e-11	775	36	14	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	6.71e-11	777	36	14	PS00028
Domain	Znf_C2H2-like	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	9.23e-11	796	36	14	IPR015880
Domain	Znf_C2H2	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	1.07e-10	805	36	14	IPR007087
Domain	ZnF_C2H2	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	1.13e-10	808	36	14	SM00355
Domain	KRAB	ZNF202 ZNF227 ZNF160 ZNF875 ZNF169 ZNF546 ZFP57 ZNF316	3.19e-07	358	36	8	PS50805
Domain	KRAB	ZNF202 ZNF227 ZNF160 ZNF875 ZNF169 ZNF546 ZFP57 ZNF316	3.19e-07	358	36	8	PF01352
Domain	KRAB	ZNF202 ZNF227 ZNF160 ZNF875 ZNF169 ZNF546 ZFP57 ZNF316	4.02e-07	369	36	8	SM00349
Domain	KRAB	ZNF202 ZNF227 ZNF160 ZNF875 ZNF169 ZNF546 ZFP57 ZNF316	4.10e-07	370	36	8	IPR001909
Domain	zf-C2H2_6	ZNF672 ZNF227 ZNF160 ZNF169 ZNF546 ZNF316 ZNF646	1.95e-06	314	36	7	PF13912
Domain	C2H2_Znf_fam	ZNF202 ZNF444	9.71e-04	24	36	2	IPR027775
Domain	SCAN	ZNF202 ZNF444	5.21e-03	56	36	2	SM00431
Domain	SCAN_BOX	ZNF202 ZNF444	5.58e-03	58	36	2	PS50804
Domain	SCAN	ZNF202 ZNF444	5.58e-03	58	36	2	PF02023
Domain	SCAN_dom	ZNF202 ZNF444	5.58e-03	58	36	2	IPR003309
Domain	Retrov_capsid_C	ZNF202 ZNF444	5.77e-03	59	36	2	IPR008916
Pubmed	A method for killer-cell immunoglobulin-like receptor (KIR) 3DL1/3DS1 genotyping using DNA recovered from frozen plasma.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	23524032
Pubmed	Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	35192601
Pubmed	Development of a PCR-SSOP approach capable of defining the natural killer cell inhibitory receptor (KIR) gene sequence repertoires.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	11098931
Pubmed	Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	37647275
Pubmed	Allele diversity of the killer cell immunoglobulin-like receptors KIR3DL1/S1 and the combination with their HLA ligands in Mexican Mestizos from Mexico City.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	30365992
Pubmed	Association of the KIR3DS1013 and KIR3DL1004 alleles with susceptibility to ankylosing spondylitis.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	20131260
Pubmed	No association of KIR3DL1 or KIR3DS1 or their alleles with ankylosing spondylitis.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	19874556
Pubmed	Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	25112829
Pubmed	Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	17182560
Pubmed	Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	17694054
Pubmed	Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	27708262
Pubmed	Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	19008943
Pubmed	Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	19411600
Pubmed	Investigation of killer cell immunoglobulin-like receptor gene diversity in KIR3DL1 and KIR3DS1 in a transplant population.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	18331531
Pubmed	Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	16805919
Pubmed	Contribution of functional KIR3DL1 to ankylosing spondylitis.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	20818412
Pubmed	HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	19386717
Pubmed	Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	19211742
Pubmed	Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	28942035
Pubmed	The profile of KIR3DL1 and KIR3DS1 alleles in an African American population resembles that found in African populations.	KIR3DL1 KIR3DS1	1.04e-06	2	36	2	20230527
Pubmed	Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individuals.	KIR3DL1 KIR3DS1	3.12e-06	3	36	2	12826375
Pubmed	KIR3DL1/S1 genotypes and KIR2DS4 allelic variants in the AB KIR genotypes are associated with Plasmodium-positive individuals in malaria infection.	KIR3DL1 KIR3DS1	3.12e-06	3	36	2	19859704
Pubmed	KIR3DS1/L1 and HLA-Bw4-80I are associated with HIV disease progression among HIV typical progressors and long-term nonprogressors.	KIR3DL1 KIR3DS1	3.12e-06	3	36	2	24059286
Pubmed	Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies.	KIR3DL1 KIR3DS1	3.12e-06	3	36	2	17301953
Pubmed	Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis.	KIR3DL1 KIR3DS1	3.12e-06	3	36	2	19019897
Pubmed	Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype.	KIR3DL1 KIR3DS1	3.12e-06	3	36	2	11859120
Pubmed	High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.	KIR3DL1 KIR3DS1	6.24e-06	4	36	2	19522772
Pubmed	The silent KIR3DP1 gene (CD158c) is transcribed and might encode a secreted receptor in a minority of humans, in whom the KIR3DP1, KIR2DL4 and KIR3DL1/KIR3DS1 genes are duplicated.	KIR3DL1 KIR3DS1	6.24e-06	4	36	2	15580659
Pubmed	Expression profile of KIR3DS1/KIR3DL1 receptors in association with immunological responses in TB, HIV and HIV/TB infected patients.	KIR3DL1 KIR3DS1	6.24e-06	4	36	2	37169313
Pubmed	Activating KIR genes are associated with ankylosing spondylitis in Asian populations.	KIR3DL1 KIR3DS1	6.24e-06	4	36	2	18638658
Pubmed	Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.	KIR3DL1 KIR3DS1	6.24e-06	4	36	2	27455421
Pubmed	Polymorphism and domain variability of human killer cell inhibitory receptors.	KIR3DL1 KIR3DS1	6.24e-06	4	36	2	9059894
Pubmed	Association of killer cell immunoglobulin-like receptor genotypes with microscopic polyangiitis.	KIR3DL1 KIR3DS1	1.04e-05	5	36	2	16508981
Pubmed	Killer cell immunoglobulin-like receptor genotypes in Japanese patients with type 1 diabetes.	KIR3DL1 KIR3DS1	1.04e-05	5	36	2	17990989
Pubmed	Killer cell immunoglobulin-like receptor gene polymorphism in lymphoproliferative diseases of granular lymphocytes in a Japanese population.	KIR3DL1 KIR3DS1	1.56e-05	6	36	2	20528243
Pubmed	The GLI-Kruppel family of human genes.	ZNF875 GLI4	2.18e-05	7	36	2	2850480
Pubmed	Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.	KIR3DL1 KIR3DS1	2.18e-05	7	36	2	9430220
Pubmed	Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.	ZNF444 ZFP57	2.18e-05	7	36	2	26025256
Pubmed	HLA-F and MHC-I Open Conformers Bind Natural Killer Cell Ig-Like Receptor KIR3DS1.	KIR3DL1 KIR3DS1	2.91e-05	8	36	2	27649529
Pubmed	KIR haplotype content at the allele level in 77 Northern Irish families.	KIR3DL1 KIR3DS1	2.91e-05	8	36	2	17200871
Pubmed	Human diversity in killer cell inhibitory receptor genes.	KIR3DL1 KIR3DS1	2.91e-05	8	36	2	9430221
Pubmed	Alternatively spliced forms of human killer inhibitory receptors.	KIR3DL1 KIR3DS1	3.73e-05	9	36	2	8662091
Pubmed	Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.	KIR3DL1 KIR3DS1	3.73e-05	9	36	2	18340360
Pubmed	Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.	KIR3DL1 KIR3DS1	4.66e-05	10	36	2	21206914
Pubmed	Natural killer cells and immune surveillance.	KIR3DL1 KIR3DS1	5.70e-05	11	36	2	18830515
Pubmed	[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].	KIR3DL1 KIR3DS1	5.70e-05	11	36	2	19664392
Pubmed	Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.	KIR3DL1 KIR3DS1	6.83e-05	12	36	2	20371502
Pubmed	[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].	KIR3DL1 KIR3DS1	6.83e-05	12	36	2	20137308
Pubmed	Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.	KIR3DL1 KIR3DS1	6.83e-05	12	36	2	19936734
Pubmed	Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.	KIR3DL1 KIR3DS1	6.83e-05	12	36	2	19181658
Pubmed	[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].	KIR3DL1 KIR3DS1	6.83e-05	12	36	2	17490516
Pubmed	[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].	KIR3DL1 KIR3DS1	8.07e-05	13	36	2	18687225
Pubmed	KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.	KIR3DL1 KIR3DS1	8.07e-05	13	36	2	19934297
Pubmed	Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.	KIR3DL1 KIR3DS1	8.07e-05	13	36	2	19120281
Pubmed	Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.	KIR3DL1 KIR3DS1	9.41e-05	14	36	2	19875891
Pubmed	Multiple sclerosis associates with LILRA3 deletion in Spanish patients.	KIR3DL1 KIR3DS1	9.41e-05	14	36	2	19421224
Pubmed	Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.	KIR3DL1 KIR3DS1	9.41e-05	14	36	2	15896204
Pubmed	[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].	KIR3DL1 KIR3DS1	9.41e-05	14	36	2	19489269
Pubmed	Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.	KIR3DL1 KIR3DS1	9.41e-05	14	36	2	18945962
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.	KIR3DL1 KIR3DS1	1.08e-04	15	36	2	20082646
Pubmed	Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.	KIR3DL1 KIR3DS1	1.08e-04	15	36	2	20643584
Pubmed	Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.	KIR3DL1 KIR3DS1	1.08e-04	15	36	2	19326408
Pubmed	Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.	KIR3DL1 KIR3DS1	1.08e-04	15	36	2	19926642
Pubmed	Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.	KIR3DL1 KIR3DS1	1.08e-04	15	36	2	19850842
Pubmed	Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.	KIR3DL1 KIR3DS1	1.08e-04	15	36	2	20207982
Pubmed	Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.	KIR3DL1 KIR3DS1	1.08e-04	15	36	2	19493232
Pubmed	[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].	KIR3DL1 KIR3DS1	1.08e-04	15	36	2	20356536
Pubmed	Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	19897003
Pubmed	Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	19279038
Pubmed	No association of KIR genes with Behcet's disease.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	17868255
Pubmed	A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	18643961
Pubmed	Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	19309280
Pubmed	Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	19000141
Pubmed	Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	20670355
Pubmed	Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	19527230
Pubmed	Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	20331834
Pubmed	Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	20652381
Pubmed	Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	18668235
Pubmed	HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.	KIR3DL1 KIR3DS1	1.24e-04	16	36	2	20210919
Pubmed	Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	19032228
Pubmed	The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	20173792
Pubmed	[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	19218127
Pubmed	Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	20483367
Pubmed	[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	19968064
Pubmed	KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	19169284
Pubmed	Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	20878400
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	20650299
Pubmed	Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	19450876
Pubmed	Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.	KIR3DL1 KIR3DS1	1.40e-04	17	36	2	19761533
Pubmed	Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.	KIR3DL1 KIR3DS1	1.58e-04	18	36	2	19046302
Pubmed	Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.	KIR3DL1 KIR3DS1	1.58e-04	18	36	2	19846535
Pubmed	Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.	KIR3DL1 KIR3DS1	1.58e-04	18	36	2	19630074
Pubmed	Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.	KIR3DL1 KIR3DS1	1.58e-04	18	36	2	20519398
Pubmed	Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.	KIR3DL1 KIR3DS1	1.58e-04	18	36	2	20580654
Pubmed	Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.	KIR3DL1 KIR3DS1	1.58e-04	18	36	2	20210918
Pubmed	Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.	KIR3DL1 KIR3DS1	1.76e-04	19	36	2	18778326
Pubmed	HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine.	ACE ALPP	1.76e-04	19	36	2	31345929
Pubmed	KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.	KIR3DL1 KIR3DS1	1.76e-04	19	36	2	18571006
Pubmed	Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.	KIR3DL1 KIR3DS1	1.76e-04	19	36	2	20600442
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of Paraná.	KIR3DL1 KIR3DS1	1.76e-04	19	36	2	18848853
Interaction	LTBP2 interactions	ZNF444 GLI4 ZNF316 ZNF646	1.57e-05	85	36	4	int:LTBP2
Interaction	EFEMP1 interactions	ZNF444 GLI4 ZNF316 ZNF646	6.69e-05	123	36	4	int:EFEMP1
Interaction	CENPB interactions	TSPYL6 GLI4 DKK2 ZNF169	6.91e-05	124	36	4	int:CENPB
Interaction	ZNF316 interactions	GLI4 ZNF169 ZNF316	7.54e-05	46	36	3	int:ZNF316
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF444 ZNF227 ZNF160 KIR3DL1 ZNF665 ZNF875 ZNF546	3.38e-05	1192	36	7	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF202 ZNF444 ZNF536 ZNF672 ZNF227 ZNF160 ZNF665 ZNF875 GLI4 ZNF169 ZNF546 ZFP57 ZNF316 ZNF646	2.66e-13	718	27	14	28
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR3DL1 KIR3DS1	3.24e-04	18	27	2	620
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ART1 KIR3DL1 ACE	2.04e-02	394	27	3	471
Disease	hepatitis C (is_implicated_in)	KIR3DL1 KIR3DS1 GRAP2	4.10e-06	28	33	3	DOID:1883 (is_implicated_in)
Disease	COVID-19 (is_implicated_in)	ACE KIR3DS1	2.51e-04	21	33	2	DOID:0080600 (is_implicated_in)
Disease	malaria (is_implicated_in)	KIR3DL1 KIR3DS1	3.30e-04	24	33	2	DOID:12365 (is_implicated_in)
Disease	tuberculosis (is_implicated_in)	KIR3DL1 KIR3DS1	4.50e-04	28	33	2	DOID:399 (is_implicated_in)
Disease	human immunodeficiency virus infectious disease (is_implicated_in)	KIR3DL1 KIR3DS1	8.76e-04	39	33	2	DOID:526 (is_implicated_in)
Disease	liver cirrhosis (is_implicated_in)	ACE KIR3DS1	1.06e-03	43	33	2	DOID:5082 (is_implicated_in)
Disease	metachronous colorectal adenoma	ZNF536 ART1	1.17e-03	45	33	2	EFO_0803377
Disease	p-tau measurement	ZNF536 LRRFIP2	2.95e-03	72	33	2	EFO_0004763
Disease	Autistic Disorder	CHD8 CACNA1H ACE	3.07e-03	261	33	3	C0004352
Disease	electroencephalogram measurement	NELL2 DKK2	3.12e-03	74	33	2	EFO_0004357
Disease	telomere length	CACNA1H TSPYL6 DKK2	5.10e-03	313	33	3	EFO_0004505

Protein segments in the cluster

Peptide	Gene	Start	Entry
RSRRHDRHHAYGRTD	CHD8	1431	Q9HCK8
NLHAYVRRALHRHYG	ACE	851	P12821
VRRALHRHYGAQHIN	ACE	856	P12821
ALDGTRHRDRNHGHY	DKK2	141	Q9UBU2
NRRRSRAVLYHLSGH	KCNH3	166	Q9ULD8
HRNEVRLHYRSGSHR	NELL2	121	Q99435
YLHHRGVAHGRLKSR	GUCY2D	656	Q02846
PGGRGHSHRDRIHYQ	MAPK8IP1	256	Q9UQF2
RGGHVTLRCHYRHRF	KIR3DL1	41	P43629
HLVQRHLADGRLYHR	MICALL2	196	Q8IY33
RARYSHRSSHHRPYL	LRRFIP2	81	Q9Y608
GNRVSRLSHLRHHYS	PPM1E	661	Q8WY54
RIDHGHHESRAYRAL	ALPP	336	P05187
AFRGRSHFFRHLRTH	GLI4	331	P10075
RYLQHHHFHQERRGG	GRAP2	221	O75791
GHRQRRAGRHTASVH	CACNA1H	501	O95180
YHSHAGAREHRRGDQ	RGMB	141	Q6NW40
RAHHRAHYETEGSRG	NFATC4	426	Q14934
RGGHVTLRCHYRHRF	KIR3DS1	41	Q14943
RHNVRLHSHDVRYGS	SDF2	36	Q99470
RHNSYLAKHRRIHTG	ZNF665	356	Q9H7R5
RTHGQSHYRRRHCSR	PRM2	46	P04554
GFGRREHVLRHQRIH	ZNF444	286	Q8N0Y2
RHNSYLATHRRIHTG	ZNF160	631	Q9HCG1
GLSRHRRVHLGYRPH	ZFP57	161	Q9NU63
HSGRLDLHLGAHRQR	ZNF672	81	Q499Z4
SRRYHLTQHFRLHTG	ZNF546	731	Q86UE3
GYRHPGSLVNHRRTH	ZNF646	56	O15015
GRAYRHRGSLVNHRH	ZNF646	471	O15015
PGRAGYRLHRRQAHS	ZNF646	891	O15015
YHLERHHRERQNGAG	ZNF536	796	O15090
GRRAALAKHQRYHAG	ZNF316	701	A6NFI3
GFGRSLNLRHHQRVH	ZNF227	696	Q86WZ6
RRGHGPQSFIHRNRH	TSPYL6	331	Q8N831
GRGFRQHSHLVRHKR	ZNF875	391	P10072
RAHSHGTRARGRQGY	TREX2	156	Q9BQ50
SRGYHLIRHQRTHSE	ZNF202	631	O95125
GRGFSQKSHLHRHRR	ZNF169	576	Q14929
REAGRSRAHYLHHFS	ART1	136	P52961