Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of neurotransmitter secretion

CACNA1A MYOF DVL1 PNKD DYSF BGLAP

4.87e-06118766GO:0046928
GeneOntologyBiologicalProcessregulation of neurotransmitter transport

CACNA1A MYOF DVL1 PNKD DYSF BGLAP

1.35e-05141766GO:0051588
GeneOntologyBiologicalProcesssignal release from synapse

CACNA1A MYOF DVL1 PNKD DYSF BGLAP

8.34e-05195766GO:0099643
GeneOntologyBiologicalProcessneurotransmitter secretion

CACNA1A MYOF DVL1 PNKD DYSF BGLAP

8.34e-05195766GO:0007269
GeneOntologyCellularComponentGATOR1 complex

NPRL2 NPRL3

1.30e-045762GO:1990130
DomainFerA

MYOF DYSF

4.89e-053762SM01200
DomainFerlin_A-domain

MYOF DYSF

4.89e-053762IPR012560
DomainFerA

MYOF DYSF

4.89e-053762PF08165
DomainDysFC

MYOF DYSF

9.75e-054762SM00694
DomainDysFN

MYOF DYSF

9.75e-054762SM00693
DomainPeroxin/Ferlin

MYOF DYSF

9.75e-054762IPR006614
DomainUbiquitin-rel_dom

FRMD4A SF3A1 FRMD7 FRMPD1 DVL1 HERPUD1

1.04e-04184766IPR029071
DomainFerI

MYOF DYSF

1.62e-045762SM01202
DomainFerB

MYOF DYSF

1.62e-045762SM01201
DomainFerlin_B-domain

MYOF DYSF

1.62e-045762IPR012561
DomainFerlin_C

MYOF DYSF

1.62e-045762PF16165
DomainFerlin_C

MYOF DYSF

1.62e-045762IPR032362
DomainFerIin_dom

MYOF DYSF

1.62e-045762IPR012968
DomainFerI

MYOF DYSF

1.62e-045762PF08151
DomainFerB

MYOF DYSF

1.62e-045762PF08150
DomainFERM_N

FRMD4A FRMD7 FRMPD1

3.24e-0433763PF09379
DomainFERM_N

FRMD4A FRMD7 FRMPD1

3.24e-0433763IPR018979
DomainPH_dom-like

MAPK8IP1 FRMD4A FRMD7 FRMPD1 TRIOBP EPS8L1 PLEKHA6 ARHGAP27

3.33e-04426768IPR011993
DomainFERM_M

FRMD4A FRMD7 FRMPD1

8.67e-0446763PF00373
Domain-

FRMD4A FRMD7 FRMPD1

1.04e-03497631.20.80.10
DomainFERM_central

FRMD4A FRMD7 FRMPD1

1.04e-0349763IPR019748
DomainFERM_domain

FRMD4A FRMD7 FRMPD1

1.04e-0349763IPR000299
DomainFERM_1

FRMD4A FRMD7 FRMPD1

1.11e-0350763PS00660
DomainFERM_2

FRMD4A FRMD7 FRMPD1

1.11e-0350763PS00661
DomainFERM_3

FRMD4A FRMD7 FRMPD1

1.11e-0350763PS50057
DomainBand_41_domain

FRMD4A FRMD7 FRMPD1

1.11e-0350763IPR019749
DomainB41

FRMD4A FRMD7 FRMPD1

1.11e-0350763SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

FRMD4A FRMD7 FRMPD1

1.11e-0350763IPR014352
DomainRRM_1

RBM15 RBM12B RBM5 SNRNP70 RBM17

1.59e-03208765PF00076
DomainRRM_dom

RBM15 RBM12B RBM5 SNRNP70 RBM17

2.33e-03227765IPR000504
DomainRRM

RBM15 RBM12B RBM5 SNRNP70 RBM17

2.46e-03230765PS50102
Domain-

MAP1A PNKD

2.96e-03207623.60.15.10
DomainMetallo-B-lactamas

MAP1A PNKD

2.96e-0320762IPR001279
Domain-

RBM15 RBM12B RBM5 SNRNP70 RBM17

3.18e-032447653.30.70.330
DomainEz/rad/moesin-like

FRMD4A FRMD7

3.26e-0321762IPR000798
DomainEPHD

KMT2C BRPF1

3.58e-0322762PS51805
DomainG_patch

RBM5 RBM17

3.91e-0323762SM00443
DomainG_patch_dom

RBM5 RBM17

3.91e-0323762IPR000467
DomainG_PATCH

RBM5 RBM17

3.91e-0323762PS50174
DomainG-patch

RBM5 RBM17

3.91e-0323762PF01585
DomainNucleotide-bd_a/b_plait

RBM15 RBM12B RBM5 SNRNP70 RBM17

4.03e-03258765IPR012677
DomainFERM_CS

FRMD4A FRMD7

4.26e-0324762IPR019747
DomainDHHC

KMT2C ZDHHC8

4.61e-0325762PS50216
DomainZnf_DHHC_palmitoyltrfase

KMT2C ZDHHC8

4.61e-0325762IPR001594
DomainFERM_C

FRMD4A FRMD7

4.99e-0326762PF09380
Domain-

MAPK8IP1 FRMD4A FRMD7 TRIOBP PLEKHA6 ARHGAP27

5.17e-033917662.30.29.30
DomainFERM_C

FRMD4A FRMD7

5.37e-0327762SM01196
DomainFERM_PH-like_C

FRMD4A FRMD7

5.37e-0327762IPR018980
DomainPHD

KMT2C BRPF1 UBR7

5.72e-0389763SM00249
DomainZnf_PHD

KMT2C BRPF1 UBR7

6.09e-0391763IPR001965
DomainZF_PHD_2

KMT2C BRPF1 UBR7

6.85e-0395763PS50016
DomainZF_PHD_1

KMT2C BRPF1 UBR7

7.06e-0396763PS01359
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

ARHGAP32 RBM15 MAT2B SF3A1 NISCH BRPF1 RBM5 ZMYM2 MAGI3 ROBO1 SNRNP70 PNKD CCDC86

1.22e-07916781332203420
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MYOF ARHGAP32 BRSK2 MAGI3 IRF2BPL MINAR1 PLEKHA6 PNKD UBN2 HERPUD1

1.59e-07493781015368895
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

RBM15 LLGL1 MAP1A RBM12B SF3A1 PCDH15 RBM5 TRIOBP ZMYM2 ZC3H18 SNRNP70 CCDC86 RBM17

8.07e-071082781338697112
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CACNA1A MAPK8IP1 FRMD4A ARHGAP32 C1orf198 ACACB MAP1A DVL1 BRSK2 TRIOBP SNRNP70 CEP170B RBM17

1.43e-061139781336417873
Pubmed

The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.

SF3A1 ZC3H18 SNRNP70

2.35e-061278323793891
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ARHGAP32 LLGL1 ACACB NISCH TRIOBP ITGA6 ROBO1 PLEKHA6

4.83e-0642178836976175
Pubmed

Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.

MYOF DYSF

4.97e-06278211959863
Pubmed

Loss of dysferlin or myoferlin results in differential defects in excitation-contraction coupling in mouse skeletal muscle.

MYOF DYSF

4.97e-06278234354129
Pubmed

Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin.

MYOF DYSF

4.97e-06278231004665
Pubmed

Mutations in the mammalian target of rapamycin pathway regulators NPRL2 and NPRL3 cause focal epilepsy.

NPRL2 NPRL3

4.97e-06278226505888
Pubmed

While dysferlin and myoferlin are coexpressed in the human placenta, only dysferlin expression is responsive to trophoblast fusion in model systems.

MYOF DYSF

4.97e-06278219228595
Pubmed

Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b.

MYOF DYSF

4.97e-06278218495154
Pubmed

A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex.

NPRL2 NPRL3

4.97e-06278219521502
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ARHGAP32 C1orf198 LLGL1 SCYL1 ITGA6 MAGI3 EPS8L1 PLEKHA6 C6orf132

4.99e-0656578925468996
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MYOF MAP1A BRPF1 DVL1 TRIOBP PATL1 LSM14B DYSF UBN2 RBM17

5.05e-06724781036232890
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

KMT2C RBM15 SF3A1 RBM5 ZMYM2 BEND3 ZC3H18 SLFN5 SNRNP70 UBN2 CCDC86 NDUFB10 RBM17

5.74e-061294781330804502
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

KMT2C RBM15 MAT2B SF3A1 RBM5 ZMYM2 BEND3 MED13L LSM14B SNRNP70 UBN2 RBM17

6.16e-061103781234189442
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 KMT2C MYOF NISCH DVL1 NPRL3 MED13L ARRDC2 DYSF ZDHHC8 CEP170B C6orf132

6.28e-061105781235748872
Pubmed

Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.

SF3A1 RBM5 ZC3H18 SNRNP70 RBM17

6.31e-0611578517332742
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

KMT2C MYOF OBSL1 TRIOBP MINAR1 MED13L

1.19e-0522578612168954
Pubmed

FerA is a Membrane-Associating Four-Helix Bundle Domain in the Ferlin Family of Membrane-Fusion Proteins.

MYOF DYSF

1.49e-05378230026467
Pubmed

Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.

NPRL2 NPRL3

1.49e-05378235338845
Pubmed

Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle Cells and Binds to Dysferlin and Myoferlin.

MYOF DYSF

1.49e-05378237434585
Pubmed

The C2 domains of otoferlin, dysferlin, and myoferlin alter the packing of lipid bilayers.

MYOF DYSF

1.49e-05378223859474
Pubmed

Seizure features and outcomes in 50 children with GATOR1 variants: A retrospective study, more favorable for epilepsy surgery.

NPRL2 NPRL3

1.49e-05378237259768
Pubmed

The landscape of epilepsy-related GATOR1 variants.

NPRL2 NPRL3

1.49e-05378230093711
Pubmed

Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia.

NPRL2 NPRL3

1.49e-05378227173016
Pubmed

Dysferlin and myoferlin regulate transverse tubule formation and glycerol sensitivity.

MYOF DYSF

1.49e-05378224177035
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MYOF RBM15 NPRL2 SF3A1 TAX1BP1 DVL1 NPRL3 PATL1 PLEKHA6 MED13L SNRNP70 RBM17

2.09e-051247781227684187
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ARHGAP32 C1orf198 COMMD1 TRIOBP BEND3 CEP170B

2.21e-0525178629778605
Pubmed

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

SF3A1 SNRNP70 RBM17

2.41e-05257839731529
Pubmed

Derlin-3 Is Required for Changes in ERAD Complex Formation under ER Stress.

DERL2 HERPUD1

2.97e-05478232858914
Pubmed

Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.

NPRL2 NPRL3

2.97e-05478229590090
Pubmed

AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.

MYOF DYSF

2.97e-05478217185750
Pubmed

Dorsal telencephalon-specific Nprl2- and Nprl3-knockout mice: novel mouse models for GATORopathy.

NPRL2 NPRL3

2.97e-05478234965576
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

MYOF RBM15 IGHG1 RBM5 MED13L RBM17

3.47e-0527278631010829
Pubmed

Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.

MYOF DYSF

4.94e-05578224687993
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RBM15 SF3A1 ZMYM2 BEND3 ZC3H18 SNRNP70 UBN2 CCDC86 NDUFB10 RBM17

5.36e-05954781036373674
Pubmed

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.

SF3A1 SNRNP70 CCDC86 UBR7 RBM17

5.76e-0518278526527279
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYOF RBM15 SF3A1 BRPF1 ZMYM2 IRF2BPL ZC3H18 PATL1 CCDC86

5.92e-0577478915302935
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

RBM15 LLGL1 ZMYM2 ZC3H18 ARRDC2 RBM17

7.55e-0531378638270169
Pubmed

Human transcription factor protein interaction networks.

KMT2C ARHGAP32 ACACB ZMYM2 BEND3 IRF2BPL ZC3H18 PATL1 LSM14B SNRNP70 UBN2 CCDC86

7.81e-051429781235140242
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

RBM15 RBM12B SF3A1 RBM5 ZC3H18 PATL1 LSM14B SNRNP70 CCDC86

8.14e-0580778922681889
Pubmed

Rare De Novo Missense Variants in RNA Helicase DDX6 Cause Intellectual Disability and Dysmorphic Features and Lead to P-Body Defects and RNA Dysregulation.

PATL1 LSM14B

1.04e-04778231422817
Pubmed

A human MAP kinase interactome.

KMT2C ARHGAP32 MAP1A ZMYM2 ROBO1 PLEKHA6 HERPUD1

1.12e-0448678720936779
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RBM15 SF3A1 BRPF1 RBM5 IRF2BPL ZC3H18 SNRNP70 CCDC86 RBM17

1.17e-0484778935850772
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

KMT2C MYOF UTP25 RBM5 TRIOBP ZMYM2 LSM14B PNKD UBN2 CCDC86 CEP170B C6orf132

1.21e-041497781231527615
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A C1orf198 MAP1A BRSK2 PLEKHA6 CEP170B

1.33e-0434778617114649
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

RBM15 RBM12B SF3A1 RBM5 SNRNP70 RBM17

1.33e-0434778616033648
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MAPK8IP1 NPRL2 COMMD1 NISCH OBSL1 TRIOBP ZMYM2 MAGI3 ROBO1 MED13L SNRNP70

1.35e-041285781135914814
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

RBM12B ZMYM2 BEND3 SNRNP70 UBN2 CCDC86

1.37e-0434978625665578
Pubmed

Death by splicing: tumor suppressor RBM5 freezes splice-site pairing.

RBM5 SNRNP70

1.38e-04878218951082
Pubmed

Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.

NPRL2 NPRL3

1.38e-04878226582740
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

ACACB MAT2B TAX1BP1 ITGA6 ZC3H18 PMEPA1 CEP170B

1.38e-0450378736217030
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

RBM15 ZC3H18 EPS8L1 SLFN5 SNRNP70 CCDC86

1.64e-0436178626167880
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

MAP1A SEPTIN4 PLEKHA6 ZDHHC8 CEP170B

1.76e-0423178516452087
Pubmed

Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.

PCDH15 ROBO1

1.77e-04978223144817
Pubmed

The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.

NPRL2 NPRL3

1.77e-04978225936802
Pubmed

A Cellular Mechanism to Detect and Alleviate Reductive Stress.

NPRL2 NPRL3

1.77e-04978232941802
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

RBM15 ACACB IGHG1 BRPF1 SNRNP70

1.87e-0423478536243803
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RBM15 ACACB RBM5 IRF2BPL MCM10 SNRNP70

1.88e-0437078622922362
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

MYOF ARHGAP32 C1orf198 LLGL1 ROBO1 ZDHHC8

2.08e-0437778638117590
Pubmed

Autosomal Dominant Sleep-Related Hypermotor (Hyperkinetic) Epilepsy

NPRL2 NPRL3

2.21e-041078220301348
Pubmed

A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.

SF3A1 SNRNP70

2.21e-041078211500380
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

KMT2C RBM15 RBM5 ZC3H18 RBM17

2.59e-0425178531076518
Pubmed

Strain background effects and genetic modifiers of hearing in mice.

MAP1A PCDH15

2.70e-041178216579977
Pubmed

Identification of neuroglobin-interacting proteins using yeast two-hybrid screening.

MAP1A DVL1

2.70e-041178222079573
Pubmed

gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.

DERL2 HERPUD1

2.70e-041178226424800
Pubmed

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.

NPRL2 NPRL3

2.70e-041178223723238
Pubmed

A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.

RBM12B SF3A1 RBM5 PATL1 RBM17

2.73e-0425478528431233
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

FRMD4A ARHGAP32 LLGL1 FRMD7 ITGA6 PLEKHA6 ZDHHC8

2.93e-0456978730639242
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A MAPK8IP1 ARHGAP32 NISCH TAX1BP1 TRIOBP ZMYM2 UBN2 CEP170B

3.04e-0496378928671696
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NISCH FRMPD1 OBSL1 BEND3 MED13L CEP170B

3.13e-0440778612693553
Pubmed

Derlin2 protein facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum.

DERL2 HERPUD1

3.23e-041278223867461
Pubmed

p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling.

MAP1A NDUFB10

3.23e-041278216537434
Pubmed

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.

NPRL2 NPRL3

3.23e-041278225263562
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

FRMD4A MYOF PCDH15 MCM10 GDF10 RBM17

3.47e-0441578616385451
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RBM15 MAP1A OBSL1 ZMYM2 ZC3H18 UBN2 CEP170B

3.57e-0458878738580884
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RBM15 UTP25 RBM12B SF3A1 RBM5 ZMYM2 MCM10 SNRNP70 CCDC86

3.69e-0498978936424410
Pubmed

Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.

NPRL2 NPRL3

3.81e-041378226051179
Pubmed

Structure of the nutrient-sensing hub GATOR2.

NPRL2 NPRL3

3.81e-041378235831510
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

EPHB4 MAPK8IP1 NPRL2 NPRL3 ITGA6

3.99e-0427678528319085
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ARHGAP32 ACACB MAP1A SCYL1 IRF2BPL C6orf132

4.18e-0443078635044719
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

RBM15 SF3A1 RBM5 BEND3 ZC3H18 SNRNP70 RBM17

4.23e-0460578728977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

BRPF1 ZMYM2 ZC3H18 MCM10 UBN2 CCDC86 UBR7

4.36e-0460878736089195
Pubmed

Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.

PCDH15 TRIOBP

4.44e-041478226754646
Pubmed

Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization.

ROBO1 CEP170B

4.44e-041478234674267
Pubmed

Network organization of the human autophagy system.

LLGL1 MAP1A SF3A1 BRSK2 OBSL1 CEP170B

4.55e-0443778620562859
Pubmed

The functional interactome landscape of the human histone deacetylase family.

RBM12B SF3A1 ZMYM2 BEND3 SNRNP70

4.92e-0428978523752268
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

C1orf198 MAP1A ZMYM2 MCM10 LSM14B UBN2

4.95e-0444478634795231
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

RBM15 ACACB SF3A1 TAX1BP1 SNRNP70 PNKD NDUFB10

5.08e-0462478733729478
Pubmed

Ring domains are essential for GATOR2-dependent mTORC1 activation.

NPRL2 NPRL3

5.12e-041578236528027
Pubmed

Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease.

MAPK8IP1 SNRNP70

5.12e-041578220205790
Pubmed

The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.

NPRL2 RBM5

5.12e-041578211085536
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

KMT2C ZMYM2 BEND3 MED13L

5.55e-0416778420362541
Pubmed

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.

DERL2 NPRL3 RBM5

5.56e-047178336305789
Pubmed

SZT2 dictates GATOR control of mTORC1 signalling.

NPRL2 NPRL3

5.84e-041678228199315
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

RBM15 TAX1BP1 MCM10 MED13L UBN2 CCDC86 UBR7

6.18e-0464578725281560
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RBM15 UTP25 SF3A1 BEND3 ZC3H18 SNRNP70 CCDC86

6.65e-0465378722586326
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

C1orf198 LLGL1 MAP1A IRF2BPL LSM14B SNRNP70

6.82e-0447278638943005
InteractionRBM17 interactions

COMMD1 SF3A1 OBSL1 RBM5 ZC3H18 SNRNP70 C6orf47 RBM17

2.02e-06218788int:RBM17
InteractionSNRNP40 interactions

RBM15 ACACB RBM12B SF3A1 DVL1 OBSL1 RBM5 BEND3 ZC3H18 SNRNP70 UBN2 RBM17

5.79e-066377812int:SNRNP40
GeneFamilyFerlin family

MYOF DYSF

1.07e-046492828
GeneFamilyRNA binding motif containing

RBM15 RBM12B RBM5 SNRNP70 RBM17

2.71e-04213495725
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMD4A FRMD7 FRMPD1

3.35e-04504931293
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

RBM5 RBM17

1.61e-0322492579
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRMD7 OBSL1 ROBO1 PLEKHA6 GDF10 PMEPA1

8.95e-071857861b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCelldroplet-Fat-Gat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 ACACB SEPTIN4 SLFN5 DYSF

1.11e-06192786c312e39003c51503c9f648332fb5c6218f33f99b
ToppCelldroplet-Fat-Gat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 ACACB SEPTIN4 SLFN5 DYSF

1.11e-06192786df09056f0e562f53b6fb30b674d2d83e9eb857d0
ToppCelldroplet-Fat-Gat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 ACACB SEPTIN4 SLFN5 DYSF

1.11e-06192786133b3ad251d72ff31e45e1dc6217945516ac63de
ToppCelldroplet-Fat-Scat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 SLFN5 DYSF

1.18e-061947860f81df418166589ea327d6dfe06674bcf2fe8f72
ToppCelldroplet-Fat-Scat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 SLFN5 DYSF

1.18e-0619478684bfe5e68069824370dc2a3f2c5958c552eaaa03
ToppCellSepsis-ICU-SEP-Myeloid-pDC|ICU-SEP / Disease, condition lineage and cell class

MAP1A ACY3 MINAR1 PMEPA1 HERPUD1 CEP170B

1.33e-06198786fe8a68bff8c1b9566eee4bfcab564f206a20ae7b
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1orf115 SEPTIN4 ITGA6 SLFN5 DYSF

1.37e-05174785b1bcd5f4505d2ccef4183fcfbf1de81964b3f9e0
ToppCellsevere-B_memory|World / disease stage, cell group and cell class

C1orf115 IGHG1 ACY3 MINAR1 HERPUD1

1.45e-051767854e5c6b1aa5ffd13593a6bcd1e1253c1737c5c2b4
ToppCellPBMC-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

C1orf115 OBSL1 PLEKHA6 DYSF BGLAP

1.53e-051787850667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 DYSF C6orf47

1.57e-0517978508cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellThalamus-Endothelial|Thalamus / BrainAtlas - Mouse McCarroll V32

EPHB4 MYOF C1orf115 SLFN5 DYSF

1.89e-05186785dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 C1orf115 ITGA6 SLFN5 DYSF

2.04e-05189785ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 C1orf115 ITGA6 SLFN5 DYSF

2.04e-05189785e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCellfacs-Trachea-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 C1orf115 ITGA6 SLFN5 DYSF

2.04e-05189785f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.10e-05190785d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCellfacs-SCAT-Fat-18m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.10e-05190785b0c9dae8189d407c94964c6bfe3ef92035245357
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.10e-05190785dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCellfacs-SCAT-Fat-18m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.10e-05190785ee63dc04e91ad49aa7820c98e97261176ecebaa6
ToppCellfacs-SCAT-Fat-18m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.10e-051907850e50808bfc3d0820524c8470ae3e8250819d65b2
ToppCellfacs-SCAT-Fat-3m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.15e-05191785a0018f88f7132477cc467ee15db029a585290595
ToppCellfacs-SCAT-Fat-3m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.15e-051917856b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCellfacs-SCAT-Fat-3m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.15e-0519178590f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCelldroplet-Fat-Scat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SEPTIN4 ITGA6 DYSF

2.32e-05194785009b005a94a5c80f6e1fdda2a0c7881a9a0ce75b
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAPK8IP1 C1orf198 MAP1A SEPTIN4 ROBO1

2.61e-051997855d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAPK8IP1 C1orf198 MAP1A SEPTIN4 ROBO1

2.61e-051997859dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAPK8IP1 C1orf198 MAP1A SEPTIN4 ROBO1

2.61e-051997856fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAPK8IP1 C1orf198 MAP1A SEPTIN4 ROBO1

2.61e-051997851bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCellControl-Lymphoid_T/NK-dn_T|Control / Disease group, lineage and cell class

FRMD7 SLFN5 GDF10 GPA33

7.35e-0512778458f47cb079c596a9119d8bf158c1681b28360ac3
ToppCellCOVID-19_Severe-NK_CD56bright|World / disease group, cell group and cell class

CKMT2 FRMPD1 SLFN5 CEP170B

1.67e-041577849dcbabb377da7e93ec9f9abf09576a92877a7e02
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A SEPTIN4 ROBO1 SLFN5

1.75e-041597845ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

MAPK8IP1 MAGI3 GDF10 C6orf132

2.01e-041657843d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1A FRMD4A ACY3 ARHGAP27

2.11e-04167784942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(peripeduncular_nucleus_&_posterior_intralaminar_thalamic_nucleus_(PP_&_PIL))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CKMT2 PSORS1C2 KCNK9

2.12e-046678385e0027bf0d4ebdcb6cac358aedd1d74aa83c612
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(peripeduncular_nucleus_&_posterior_intralaminar_thalamic_nucleus_(PP_&_PIL))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CKMT2 PSORS1C2 KCNK9

2.12e-04667836cf03dd1db7607684cdcca7df08933f8cdc3adef
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

MAP1A ACY3 PLEKHA6 PMEPA1

2.16e-0416878490f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACB BEND3 ROBO1 IRF2BPL

2.31e-041717846f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACB BEND3 ROBO1 IRF2BPL

2.31e-04171784ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

MAP1A ACY3 MINAR1 CEP170B

2.31e-0417178472c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP1A IRF2BPL C6orf47 PMEPA1

2.31e-041717847b0783d25055e5ea5b2fc44ebcb16bfd0adbcf81
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1orf115 LLGL1 BEND3 C6orf47

2.41e-041737844968712af1cca8c932abd3323631d7dcaffd4a66
ToppCellsevere-B_memory|severe / disease stage, cell group and cell class

C1orf115 ACY3 MINAR1 HERPUD1

2.41e-041737843a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCelldroplet-Fat-SCAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 RBM12B ITGA6 SLFN5

2.41e-04173784eb58b0189e71e38d4f4f1cf544a82cde8d1c86bc
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SEPTIN4 IRF2BPL EPS8L1 BGLAP

2.47e-04174784e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAPK8IP1 MYOF NISCH TRIOBP

2.47e-041747841d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF ACY3 PSORS1C2 EPS8L1

2.52e-04175784c1a8a55af825d5913095f919fa860828df9c273e
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF ACY3 PSORS1C2 EPS8L1

2.52e-0417578478b453e220218c84557f244ef7a760e4a1952761
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1orf115 ACACB SEPTIN4 SLFN5

2.52e-041757847be76d39e1a4f4ac709672cd2d409a2523a083ce
ToppCellwk_20-22-Epithelial-PNS-Late_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

C1orf198 BRSK2 ITGA6 PMEPA1

2.58e-0417678481924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 ITGA6 SLFN5 BGLAP

2.58e-04176784a3f27b5d7edf2d396c085efbe35305cfa0afa565
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SLFN5 DYSF GDF10

2.58e-041767840b3491451be02c18a16cdb875645be47eb867a7f
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SLFN5 DYSF

2.58e-04176784eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAP1A ACY3 PMEPA1 HERPUD1

2.63e-04177784e36c2005be74ee8ff03c2052504cb496faf86009
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 MAP1A RBM12B DYSF

2.69e-041787846bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CKMT2 SEPTIN4 SLFN5 DYSF

2.69e-04178784a3f95f0002f408b5b6c57e28b297b5b2737e919c
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ITGA6 ARHGAP27 ARRDC2 DYSF

2.75e-04179784ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ITGA6 ARHGAP27 ARRDC2 DYSF

2.75e-0417978435fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCellnormal_Lung-B_lymphocytes|normal_Lung / Location, Cell class and cell subclass

MAP1A IGHG1 PMEPA1 HERPUD1

2.75e-041797845b89193486100b6754c1c5eca3105ea955805eae
ToppCellCOPD-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

FRMD4A ABHD5 ACACB GPA33

3.05e-041847847fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 ITGA6 SLFN5 DYSF

3.11e-04185784dec60254204014083ff3b4aec0cc75410950a486
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 ITGA6 SLFN5 DYSF

3.11e-04185784201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 ITGA6 SLFN5 DYSF

3.11e-04185784334f006c3ef33338ff8d649309d3f448733a3a99
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB4 PCDH15 ITGA6 DYSF

3.18e-04186784055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCellE12.5-Endothelial|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C1orf115 ITGA6 ARHGAP27 DYSF

3.24e-04187784b8ed57b3c39ffbf750cd08a3e03ec11dae43d00e
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|368C / Donor, Lineage, Cell class and subclass (all cells)

C1orf115 MAGI3 CEP170B C6orf132

3.24e-04187784b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-pDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAP1A ACY3 PMEPA1 HERPUD1

3.24e-04187784bf64a6ef5062ec9a0f7095e8c97ce66bfc3bf179
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|368C / Donor, Lineage, Cell class and subclass (all cells)

C1orf115 MAGI3 CEP170B C6orf132

3.24e-0418778461c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCellwk_20-22-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EPHB4 ITGA6 EPS8L1 DYSF

3.24e-0418778455aad84b992412e487a32f4970620189a7380ba6
ToppCellcontrol-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MAP1A OBSL1 PMEPA1 HERPUD1

3.24e-04187784c78aee98b32719aa45811b620fc97be1ecf5fd53
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 ITGA6 SLFN5 DYSF

3.31e-04188784ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1orf115 ITGA6 SLFN5 DYSF

3.31e-0418878420072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCelldroplet-Fat-Scat-21m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 ITGA6 DYSF

3.31e-041887848671fdbc4138e6f9559920779c98628ed80f0da3
ToppCellfacs-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1orf115 ITGA6 SLFN5 DYSF

3.31e-04188784dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 SLFN5 DYSF

3.31e-0418878405de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 ITGA6 SLFN5 DYSF

3.31e-04188784e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCelldroplet-Fat-SCAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 ITGA6 DYSF

3.31e-041887845cf060bb8adaefa9964187195d67993c1248ef47
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1orf115 ITGA6 SLFN5 DYSF

3.31e-041887846ab5ce8569f896a0fe7a76b8b4a83661e5499b8c
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 ITGA6 SLFN5 DYSF

3.31e-041887840fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRMD4A ABHD5 ACACB GPA33

3.31e-04188784d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCelldroplet-Fat-SCAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 ITGA6 DYSF

3.31e-04188784449f9602df3c83b2110eb479a00d428d1b55b423
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 ITGA6 SLFN5 DYSF

3.38e-04189784f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD1 PCDH15 ROBO1 PMEPA1

3.38e-04189784f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 SLFN5 DYSF

3.38e-041897848ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 ITGA6 SLFN5 DYSF

3.38e-04189784e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 SLFN5 DYSF

3.38e-04189784403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 ITGA6 SLFN5 DYSF

3.38e-041897845559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellfacs-GAT-Fat-24m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 ITGA6 DYSF

3.44e-04190784da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SLFN5 DYSF

3.44e-041907849d5242759546be0089981ef1877e4ed5f81face5
ToppCellfacs-GAT-Fat-24m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 ITGA6 DYSF

3.44e-041907843395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SLFN5 DYSF

3.44e-04190784b7fc451e160e31dc898b122de844b501f587db67
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1orf115 ITGA6 SLFN5 DYSF

3.44e-04190784632d5dc11765053366d61f0a0c7916111cea4f50
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMD4A MYOF PCDH15 ROBO1

3.44e-0419078445df8fee00f8949937863159d7aa042e72748d9b
ToppCellIPF-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

FRMD4A ABHD5 ACACB GPA33

3.44e-041907842592765016f291565697265800a232b2edef3792
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 ITGA6 DYSF

3.44e-04190784c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCellfacs-GAT-Fat-24m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 ITGA6 DYSF

3.44e-04190784e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf115 SEPTIN4 ITGA6 DYSF

3.44e-041907845174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCellhematopoetic_progenitors-CD34+_CLP|hematopoetic_progenitors / Lineage and Cell class

ARHGAP27 MED13L ARRDC2 HERPUD1

3.44e-04190784117abdafd294c85ccb5d8ea907e3c0491b7200b2
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SLFN5 DYSF

3.44e-0419078483cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACACB ITGA6 ARHGAP27 DYSF

3.44e-04190784106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 C1orf115 SLFN5 DYSF

3.44e-041907845f440d4b334d66d419c03bd828f7d93f16c1ce67
DiseaseFamilial focal epilepsy with variable foci

NPRL2 NPRL3

1.91e-053752cv:C1858477
DiseaseEpilepsy, Partial, with Variable Foci

NPRL2 NPRL3

1.91e-053752C1858477
Diseasefocal epilepsy (is_implicated_in)

NPRL2 NPRL3

3.81e-054752DOID:2234 (is_implicated_in)
DiseaseSpinocerebellar Ataxia Type 2

CACNA1A SCYL1 RBM17

8.92e-0534753C0752121
DiseaseSpinocerebellar Ataxia Type 1

CACNA1A SCYL1 RBM17

8.92e-0534753C0752120
DiseaseSpinocerebellar Ataxia Type 5

CACNA1A SCYL1 RBM17

8.92e-0534753C0752123
DiseaseSpinocerebellar Ataxia Type 7

CACNA1A SCYL1 RBM17

8.92e-0534753C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

CACNA1A SCYL1 RBM17

8.92e-0534753C0752124
DiseaseAtaxia, Spinocerebellar

CACNA1A SCYL1 RBM17

8.92e-0534753C0087012
DiseaseSpinocerebellar Ataxia Type 4

CACNA1A SCYL1 RBM17

9.74e-0535753C0752122
DiseaseChildhood Absence Epilepsy

CACNA1A KCNK9

1.33e-047752C4281785
DiseaseEpilepsy, Minor

CACNA1A KCNK9

1.33e-047752C4552765
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

MYOF DYSF

1.33e-047752DOID:11724 (implicated_via_orthology)
DiseaseAbsence Epilepsy

CACNA1A KCNK9

1.33e-047752C0014553
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A SCYL1

1.33e-047752DOID:0050951 (implicated_via_orthology)
DiseaseAkinetic Petit Mal

CACNA1A KCNK9

1.33e-047752C0001890
DiseaseEpilepsy, Absence, Atypical

CACNA1A KCNK9

1.33e-047752C0751124
DiseaseAbsence Seizure Disorder

CACNA1A KCNK9

1.33e-047752C4553705
DiseaseJuvenile Absence Epilepsy

CACNA1A KCNK9

1.33e-047752C4317339
Diseasecortical surface area measurement

CACNA1A NPRL2 BRSK2 TRIOBP BEND3 ROBO1 ARHGAP27 MED13L DYSF C6orf47 GDF10 PMEPA1

1.40e-0413457512EFO_0010736
Diseaseresponse to high fat food intake, triglyceride change measurement

BEND3 GDF10

2.27e-049752EFO_0007681, EFO_0007684
Diseasecystic kidney disease (implicated_via_orthology)

EPHB4 ROBO1

2.83e-0410752DOID:2975 (implicated_via_orthology)
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

OBSL1 HERPUD1

1.06e-0319752EFO_0004612, EFO_0008589
Diseaseapolipoprotein B measurement

MYOF LLGL1 ACACB NISCH PSORS1C2 PMEPA1 HERPUD1

1.48e-03663757EFO_0004615
Diseasemean arterial pressure

UTP25 NPRL3 ROBO1 SNRNP70 GDF10 RBM17

1.71e-03499756EFO_0006340
DiseaseNeurodevelopmental Disorders

KMT2C BRSK2 MED13L

1.74e-0393753C1535926
Diseasehearing impairment

ABHD5 PCDH15 TRIOBP

2.02e-0398753C1384666
Diseasecholesterol to total lipids in small LDL percentage

IGHG1 HERPUD1

2.15e-0327752EFO_0022241

Protein segments in the cluster

PeptideGeneStartEntry
PPPDKDRYAQERPDH

CACNA1A

2221

O00555
RPTPDDPYEVTRARE

ACY3

81

Q96HD9
ESPQRQPEYSPESPR

CCDC86

101

Q9H6F5
LPDAQRQGEPYPERP

CEP170B

181

Q9Y4F5
ERYEPLEEPAPSEQP

C1orf115

76

Q9H7X2
ALPERPEAPPEYSEV

ARRDC2

331

Q8TBH0
EEDPRLPDNFRPPGE

RBM12B

856

Q8IXT5
PPLPRDLERERDYPF

RBM15

321

Q96T37
PERPRPEDQRLIYSG

HERPUD1

46

Q15011
PEEPRPSRPRYKADV

KCNK9

276

Q9NPC2
RPLPEPYEASRDLAQ

LLGL1

801

Q15334
NPERFREEFEGPPLP

BEND3

676

Q5T5X7
DREIEFLPSRAPYDP

ACACB

2031

O00763
PEPAPETPFIYRLER

OBSL1

541

O75147
EYALPQRPPQGPEDD

PATL1

151

Q86TB9
PYERPALTPRPIDNF

KMT2C

2071

Q8NEZ4
PEQREPTPYPDERSF

MAP1A

1951

P78559
YRLPPSDDAEFRPPE

MED13L

636

Q71F56
DGTNPPYREEDIPAP

MAT2B

141

Q9NZL9
NRAEVPARPAPQEPY

MAGI3

836

Q5TCQ9
NAIEQDYRLPPPPDC

EPHB4

831

P54760
KEDARPNREAYEEPP

GPA33

271

Q99795
PNREAYEEPPEQLRE

GPA33

276

Q99795
AIGEEYEEAPRPQPP

MAPK8IP1

426

Q9UQF2
YEEAPRPQPPACLSE

MAPK8IP1

431

Q9UQF2
RPTDRPAPPREEIYE

LSM14B

51

Q9BX40
EPNPNPDPRDIFSER

FRMD7

426

Q6ZUT3
KERYPSQEDEDLPPR

BRSK2

341

Q8IWQ3
DSEERDPGVPRPSPY

GDF10

226

P55107
PPCYRQEPAPKDREA

C1orf198

226

Q9H425
EQRSRFEYPPPPVSL

IRF2BPL

166

Q9H1B7
DKDVYPEPPRRTPVQ

NDUFB10

6

O96000
PSEEEPRPREDDVPF

NPRL3

416

Q12980
DDVLFYDESPPPRPK

MCM10

636

Q7L590
YKTRPPREQPDTFPD

ITGA6

276

P23229
RTEVPPDDEPAYCPR

ARHGAP32

1601

A7KAX9
AERREKYGIPEPPEP

RBM5

706

P52756
LYEEPAPDRPPGENE

IL20RA

521

Q9UHF4
EPQVYAPPRPTDRLA

PMEPA1

106

Q969W9
VPYPDPLEPRREVCE

BGLAP

61

P02818
EIPRFTQEEYRPPPV

PCDH15

1031

Q96QU1
IRPASQVYPDRAPEP

C6orf132

346

Q5T0Z8
EYPLDPGEEPPIVRR

FRMD4A

426

Q9P2Q2
LYIPREPSSVPPREE

C5orf60

56

A6NFR6
RPDPPYPEPRRVDSS

C6orf47

21

O95873
YTEPLLSPRDEPRSD

FRMPD1

1071

Q5SYB0
RSQLYPEVPPEEFRP

COMMD1

36

Q8N668
YFTVPRADPVRPIDP

DVL1

346

O14640
PREPQVYTLPPSRDE

IGHG1

226

P01857
TPDEDPNYNPLPEER

DERL2

211

Q9GZP9
LELSPEEGPPYRPEF

EPS8L1

406

Q8TE68
ESEDTDLPYPPPQRE

DYSF

1301

O75923
DEYPPPARRQQETLD

FAM166A

181

Q6J272
VREQPRLFPPSADYP

CKMT2

41

P17540
PAPERRPTYLVPKDQ

MINAR1

406

Q9UPX6
REFEDPRDAPPPTRA

SNRNP70

46

P08621
YGSDPEERPPNLKRP

UTP25

396

Q68CQ4
EERPPNLKRPEDYEA

UTP25

401

Q68CQ4
AFYPDEIQRPPVRVP

TAX1BP1

651

Q86VP1
EEPEPLSPELEYIPR

PNKD

51

Q8N490
VPEPRPQAPDLYDDD

SEPTIN4

61

O43236
RDPVRDFPFELIPEP

SCYL1

6

Q96KG9
DDPPEPVYANIERQP

ARHGAP27

221

Q6ZUM4
EQRPDPPVAQEYDVP

NPRL2

161

Q8WTW4
PPTPDQVIVRKDYDP

SF3A1

381

Q15459
EREEYTVLADLPPPR

TRIOBP

1266

Q9H2D6
FPERPDLADQDRPIP

ABHD5

181

Q8WTS1
YRELEQDTPDAPPRP

BRPF1

181

P55201
RPLASSPPRLYEDDE

AKAP3

631

O75969
FERLPPRSEDIYADP

PLEKHA6

481

Q9Y2H5
EREPEYPREPPRLEP

UBN2

26

Q6ZU65
PRLEPQPYREPARAE

UBN2

36

Q6ZU65
KAAIPPPVYEEQDRP

RBM17

206

Q96I25
PPVYEEQDRPRSPTG

RBM17

211

Q96I25
PLPEFAKEPPQRDRY

NISCH

1391

Q9Y2I1
LRRETYTDDLPPPPV

ROBO1

1471

Q9Y6N7
PPVFGEEYEEQPRPR

ZMYM2

1026

Q9UBW7
ICKRPYPDPEDEIPD

UBR7

136

Q8N806
PRPREPSPVRYDNLS

ZDHHC8

531

Q9ULC8
RLEDRFNSIPAEPPP

TCFL5

186

Q9UL49
LPPPSDQYPREEINR

SLFN5

696

Q08AF3
PRDVRDTVLEPYADP

ZC3H18

356

Q86VM9
RPQEEPDLDPPREEY

PSORS1C2

121

Q9UIG4
ISVEPRPEQPEPDFR

MYO1G

991

B0I1T2
DDPSVPAPPRQFREL

MYOF

1531

Q9NZM1