Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	beta-catenin-TCF complex	TCF7L1 TLE4	1.86e-04	13	33	2	GO:1990907
Pathway	REACTOME_REPRESSION_OF_WNT_TARGET_GENES	TCF7L1 TLE4	1.14e-04	10	23	2	MM15156
Pathway	REACTOME_REPRESSION_OF_WNT_TARGET_GENES	TCF7L1 TLE4	2.29e-04	14	23	2	M27402
Pubmed	Gain of LINC00624 Enhances Liver Cancer Progression by Disrupting the Histone Deacetylase 6/Tripartite Motif Containing 28/Zinc Finger Protein 354C Corepressor Complex.	SRRT HDAC6	3.33e-05	9	34	2	32869873
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	MAST1 DAPK1 DLG5 DTNB CABLES1	4.20e-05	401	34	5	25852190
Pubmed	All Tcf HMG box transcription factors interact with Groucho-related co-repressors.	TCF7L1 TLE4	6.08e-05	12	34	2	11266540
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PIKFYVE MAST1 MAN2B2	1.37e-04	102	34	3	10231032
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	PIKFYVE AP4M1 FAM135B AP3B2	1.69e-04	285	34	4	34369648
Pubmed	Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response.	MAN2B2 MGAT4C	2.12e-04	22	34	2	8673525
Pubmed	Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation.	MAN2B2 MGAT4C	2.12e-04	22	34	2	9109416
Pubmed	Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum.	MAN2B2 MGAT4C	2.12e-04	22	34	2	11530211
Pubmed	Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function.	MAN2B2 MGAT4C	2.32e-04	23	34	2	1736542
Pubmed	Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.	MAN2B2 MGAT4C	2.32e-04	23	34	2	8093218
Pubmed	Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins.	MAN2B2 MGAT4C	2.32e-04	23	34	2	3099781
Pubmed	Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.	MAN2B2 MGAT4C	2.32e-04	23	34	2	3264072
Pubmed	The AP-3 complex: a coat of many colours.	AP4M1 AP3B2	3.45e-04	28	34	2	9714600
Pubmed	Many sequence variants affecting diversity of adult human height.	ZDHHC7 DTNB CABLES1	3.71e-04	143	34	3	18391951
Pubmed	Specification of dopaminergic subsets involves interplay of En1 and Pitx3.	SULF1 TLE4	4.24e-04	31	34	2	23863478
Pubmed	Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.	FLNC HDAC6 TCF7L1	4.43e-04	152	34	3	11044609
Pubmed	Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens.	MMP12 AP3B2	5.72e-04	36	34	2	9344654
Pubmed	Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport.	MAN2B2 MGAT4C	6.05e-04	37	34	2	2542563
Pubmed	Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.	MAN2B2 MGAT4C	6.05e-04	37	34	2	2541446
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PIKFYVE ZDHHC7 FLNC DNAJC14 TEP1 CABLES1	6.37e-04	1105	34	6	35748872
Pubmed	Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis.	MAN2B2 MGAT4C	6.38e-04	38	34	2	2829950
Pubmed	Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1.	MAN2B2 MGAT4C	6.38e-04	38	34	2	2187500
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MAST1 RERE TLE4 ZNF451	6.49e-04	407	34	4	12693553
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	HDAC6 TEP1 TCF7L1 TLE4	7.56e-04	424	34	4	21731673
Pubmed	A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.	IL17RA DTNB	8.17e-04	43	34	2	25130324
Pubmed	Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.	MAN2B2 MGAT4C	9.35e-04	46	34	2	2649653
Pubmed	Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.	CBLL1 SRRT	9.75e-04	47	34	2	15009096
Cytoband	7q21	SRRT PEG10	4.13e-05	13	34	2	7q21
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	CBLL1 SRRT AP4M1	5.74e-04	219	34	3	chr7q22
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	IL17RA MGAT4C SULF1 TLE4	5.23e-06	151	34	4	f50c5ae9dae507df750df25e151b58685fec70ce
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	DNAJC14 SULF1 TCF7L1 AP3B2	1.05e-05	180	34	4	886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
Drug	citronellyl alpha-D-mannopyranosyl phosphate	MAN2B2 MGAT4C	1.30e-05	4	34	2	CID000191367
Drug	Man)5(GlcNAc)2Asn	MAN2B2 MGAT4C	1.30e-05	4	34	2	CID003082495
Drug	(2S,3S,4R,5R,6S)-2,6-difluoro-2-(hydroxymethyl)oxane-3,4,5-triol	MAN2B2 MGAT4C	2.16e-05	5	34	2	CID010013013
Disease	cervical carcinoma	TEP1 SULF1 TCF7L1	9.14e-04	182	31	3	EFO_0001061
Disease	response to bronchodilator, FEV/FEC ratio	DAPK1 MMP12 MGAT4C TLE4 FAM135B	1.13e-03	766	31	5	EFO_0004713, GO_0097366
Disease	initial pursuit acceleration	FAM135B CABLES1	3.78e-03	87	31	2	EFO_0008434
Disease	lymphocyte percentage of leukocytes	IL17RA RERE TCF7L1 TLE4	4.96e-03	665	31	4	EFO_0007993
Disease	neurotic disorder	RERE FAM135B	5.06e-03	101	31	2	EFO_0004257
Disease	Bell's palsy	POU4F3 MGAT4C	5.15e-03	102	31	2	EFO_0007167
Disease	smoking behavior	RERE MGAT4C CABLES1	5.41e-03	341	31	3	EFO_0004318
Disease	neuritic plaque measurement	SULF1 TLE4 FAM135B	5.77e-03	349	31	3	EFO_0006798

Protein segments in the cluster

Peptide	Gene	Start	Entry
KGMLEVFVAPTHHPH	DAPK1	771	P53355
HIMIYNVHAPPHGDQ	DNM1P46	86	Q6ZS02
VHPSHHPEIMRLFPR	ABHD11	271	Q8NFV4
PFSGDPHMVSVHIHF	AP3B2	881	Q13367
PGDESPVVMHHHGRH	AP4M1	41	O00189
MMHAPRCGVPDVHHF	MMP12	86	P39900
AHHIIAGRLMVIHAP	MGAT4C	161	Q9UBM8
PFIPIHHMEAHALTI	OSGEPL1	141	Q9H4B0
LAVMVHPDKNHHPRA	DNAJC14	466	Q6Y2X3
FEHMHHIPAPRPEEF	IL17RA	246	Q96F46
HRYGHSAPPFVHIIM	OR51F2	276	Q8NH61
RPAMEGPHTVHVAFA	FLNC	441	Q14315
APHAIERLHHMHIYP	DLG5	1821	Q8TDM6
HVYPDHRLVDPHIEM	PEG10	521	Q86TG7
HRLVDPHIEMIPGAH	PEG10	526	Q86TG7
THVNGEPVHGMVHPE	MAST1	1021	Q9Y2H9
EYQGQPVVSHPHHIM	CBLL1	321	Q75N03
TPMVHHIRRFVHGQG	PIKFYVE	1276	Q9Y2I7
HLPEHEVMPHYRRLV	CABLES1	616	Q8TDN4
PLMHRLAHVENVFHP	DTNB	226	O60941
PIRAFVVPHSHMDVG	MAN2B2	26	Q9Y2E5
HFHPRNGLHHQVPVM	FAM135B	141	Q49AJ0
GMAIIRPPGHHAQHS	HDAC6	206	Q9UBN7
HRGHYPIGHEAPRML	KIF2B	551	Q8N4N8
GQPPHEHEMLRHPVF	RERE	1481	Q9P2R6
EHSVMPAQIHPHHLG	POU4F3	136	Q15319
GHPDVHIMQHHVLPI	SRRT	116	Q9BXP5
RPAHILNPHHLEGDM	ZNF451	996	Q9Y4E5
MEKPHGHVSAHPDIL	TEP1	91	Q99973
VVQHPHHMHPLTPLI	TCF7L1	181	Q9HCS4
VVGFDPHHHMRVPAI	TLE4	421	Q04727
MQPSGHRLRDVEHHP	ZDHHC7	1	Q9NXF8
FIGDHVHGAPHAVMP	ZNF529	6	Q6P280
PHRPVMMVISHAAPH	SULF1	211	Q8IWU6
MVHFLHPGHTPRNIV	ZYG11A	1	Q6WRX3