Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell morphogenesis

TANC2 DIP2B DACT2 DOCK10 APC LAMA3 CDH23 NCAM1 CLASP2 ITGA4 MED1 ECT2 PREX2 FRY FAT1 EFNA2 SIPA1L1 MYPN PTPRQ CNTNAP2 AHR BAIAP2 MARK2 PALLD SOS1

2.40e-06119415325GO:0000902
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

TANC2 DIP2B DOCK10 APC LAMA3 CDH23 NCAM1 CLASP2 ITGA4 PREX2 EFNA2 SIPA1L1 MYPN PTPRQ CNTNAP2 BAIAP2 MARK2 PALLD SOS1

2.95e-0674815319GO:0048667
GeneOntologyBiologicalProcesspositive regulation of termination of DNA-templated transcription

SETX WNK1

5.47e-0521532GO:0060566
GeneOntologyBiologicalProcesspositive regulation of termination of RNA polymerase II transcription

SETX WNK1

5.47e-0521532GO:1904595
GeneOntologyBiologicalProcessneuron development

TANC2 DIP2B FAT4 SETX DOCK10 APC RAP1GAP2 LAMA3 CDH23 NCAM1 CLASP2 ITGA4 WNK1 PREX2 FARP2 FRY EFNA2 SIPA1L1 MYPN PTPRQ CNTNAP2 BAIAP2 MARK2 PALLD SOS1

7.48e-05146315325GO:0048666
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

FAT4 PCDHGB1 PCDHGA5 CDH23 FAT1 MYPN PKD1 PALLD

7.94e-051871538GO:0007156
GeneOntologyBiologicalProcessaxonogenesis

DIP2B APC LAMA3 NCAM1 CLASP2 ITGA4 EFNA2 SIPA1L1 MYPN CNTNAP2 BAIAP2 MARK2 PALLD SOS1

8.50e-0556615314GO:0007409
GeneOntologyBiologicalProcessneuron projection morphogenesis

TANC2 DIP2B DOCK10 APC LAMA3 NCAM1 CLASP2 ITGA4 PREX2 EFNA2 SIPA1L1 MYPN CNTNAP2 BAIAP2 MARK2 PALLD SOS1

9.83e-0580215317GO:0048812
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

FAT4 PCDHGB1 PCDHGA5 CDH23 ITGA4 WNK1 FAT1 MYPN PKD1 PALLD

1.19e-0431315310GO:0098742
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

TANC2 DIP2B DOCK10 APC LAMA3 NCAM1 CLASP2 ITGA4 PREX2 EFNA2 SIPA1L1 MYPN CNTNAP2 BAIAP2 MARK2 PALLD SOS1

1.26e-0481915317GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

TANC2 DIP2B DOCK10 APC LAMA3 NCAM1 CLASP2 ITGA4 PREX2 EFNA2 SIPA1L1 MYPN CNTNAP2 BAIAP2 MARK2 PALLD SOS1

1.40e-0482615317GO:0048858
GeneOntologyBiologicalProcesscell-cell adhesion

FAT4 ZNF609 PCDHGB1 NT5E PCDHGA5 LAMA3 CDH23 NCAM1 ITGA4 ITGA9 WNK1 TBX18 STK10 FAT1 ZNF608 MYPN PKD1 BAIAP2 PALLD MEGF11

1.42e-04107715320GO:0098609
GeneOntologyBiologicalProcessregulation of organelle organization

TBC1D19 SYNPO2 BCL7B APC CLASP2 ECT2 DCTN1 C2CD5 USP10 VPS13D TBC1D4 SIPA1L1 PRKAA1 BUB1 PKD1 ATF7IP2 FBXO43 SASS6 PLA2G4A MEIOSIN BAIAP2 MARK2 PAN3

1.44e-04134215323GO:0033043
GeneOntologyBiologicalProcessmaltose metabolic process

MGAM GAA

1.63e-0431532GO:0000023
GeneOntologyBiologicalProcessneuron projection development

TANC2 DIP2B FAT4 SETX DOCK10 APC RAP1GAP2 LAMA3 CDH23 NCAM1 CLASP2 ITGA4 PREX2 FRY EFNA2 SIPA1L1 MYPN CNTNAP2 BAIAP2 MARK2 PALLD SOS1

2.07e-04128515322GO:0031175
GeneOntologyCellularComponentaxon

TANC2 ATP5MC1 DIP2B SETX MYO1D PCDHGB1 APC NCAM1 CLASP2 ITGA4 OPN1SW DCTN1 PGR CACNG2 MYPN PRKAA1 CNTNAP2 TNK2 USH2A PALLD

1.01e-0589115520GO:0030424
GeneOntologyCellularComponentsomatodendritic compartment

TANC2 ATP5MC1 DIP2B MYO1D FXR2 DOCK10 APC NCAM1 ITGA4 DCTN1 PGR CACNG2 EFNA2 SIPA1L1 PRKAA1 CNTNAP2 SKOR1 TNK2 BAIAP2 MARK2 USH2A PALLD SOS1

3.78e-05122815523GO:0036477
GeneOntologyCellularComponentneuronal cell body

ATP5MC1 DIP2B MYO1D APC NCAM1 ITGA4 DCTN1 PGR EFNA2 SIPA1L1 PRKAA1 CNTNAP2 SKOR1 TNK2 BAIAP2 USH2A PALLD SOS1

4.89e-0583515518GO:0043025
GeneOntologyCellularComponentcell body

ATP5MC1 DIP2B MYO1D APC NCAM1 ITGA4 OPN1SW DCTN1 PGR EFNA2 SIPA1L1 PRKAA1 CNTNAP2 SKOR1 TNK2 BAIAP2 USH2A PALLD SOS1

6.03e-0592915519GO:0044297
GeneOntologyCellularComponentdistal axon

ATP5MC1 SETX PCDHGB1 APC NCAM1 CLASP2 ITGA4 OPN1SW PGR TNK2 USH2A PALLD

1.01e-0443515512GO:0150034
GeneOntologyCellularComponentsite of polarized growth

SETX PCDHGB1 APC NCAM1 CLASP2 ITGA4 FRY TNK2 PALLD

1.17e-042531559GO:0030427
GeneOntologyCellularComponentcation channel complex

ATP5MC1 CACHD1 CACNG2 PKD1 CNTNAP2 C2CD6 KCNMB3 ATP5F1B

3.78e-042351558GO:0034703
GeneOntologyCellularComponentgrowth cone

SETX PCDHGB1 APC NCAM1 CLASP2 ITGA4 TNK2 PALLD

4.98e-042451558GO:0030426
GeneOntologyCellularComponentbasal cortex

CLASP2 MARK2

1.12e-0371552GO:0045180
GeneOntologyCellularComponentactin-based cell projection

ATP6V1B2 MYO1D CDH23 FAT1 PTPRQ BAIAP2 USH2A PALLD

1.13e-032781558GO:0098858
DomainLAM_G_DOMAIN

FAT4 LAMA3 FAT1 CNTNAP2 USH2A

1.27e-05381505PS50025
DomainLaminin_G_2

FAT4 LAMA3 FAT1 CNTNAP2 USH2A

1.64e-05401505PF02210
DomainLamG

FAT4 LAMA3 FAT1 CNTNAP2 USH2A

2.64e-05441505SM00282
DomainLaminin_G

FAT4 LAMA3 FAT1 CNTNAP2 USH2A

1.02e-04581505IPR001791
DomainGDS_CDC24_CS

ECT2 PREX2 FARP2 SOS1

2.64e-04391504IPR001331
DomainC2_dom

PLCZ1 INPP4A C2CD5 PLA2G4A C2CD6 SEC63 TNS1

3.64e-041641507IPR000008
DomainGlyco_hydro_31_CS

MGAM GAA

3.80e-0441502IPR030459
DomainGal_mutarotase_N

MGAM GAA

3.80e-0441502IPR031727
DomainNtCtMGAM_N

MGAM GAA

3.80e-0441502PF16863
DomainATP_synth_asu_C

ATP6V1B2 ATP5F1B

6.31e-0451502IPR000793
DomainGLYCOSYL_HYDROL_F31_2

MGAM GAA

6.31e-0451502PS00707
DomainATP-synt_ab_N

ATP6V1B2 ATP5F1B

6.31e-0451502PF02874
DomainATPase_F1/V1/A1_a/bsu_N

ATP6V1B2 ATP5F1B

6.31e-0451502IPR004100
DomainATPase_a/bsu_AS

ATP6V1B2 ATP5F1B

6.31e-0451502IPR020003
DomainATP-synt_ab_C

ATP6V1B2 ATP5F1B

6.31e-0451502PF00306
DomainATP-synt_ab

ATP6V1B2 ATP5F1B

6.31e-0451502PF00006
DomainATPASE_ALPHA_BETA

ATP6V1B2 ATP5F1B

6.31e-0451502PS00152
DomainOSR1_C

WNK1 WNK3

9.41e-0461502PF12202
DomainGlyco_hydro_31_AS

MGAM GAA

9.41e-0461502IPR030458
DomainATPase_F1/V1/A1_a/bsu_nucl-bd

ATP6V1B2 ATP5F1B

9.41e-0461502IPR000194
DomainKinase_OSR1/WNK_CCT

WNK1 WNK3

9.41e-0461502IPR024678
Domain-

FAT4 LAMA3 FAT1 CNTNAP2 USH2A

1.01e-039515052.60.120.200
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

EPS15 SETX APC MED1 POLA2 WNK1 ECT2 TRIP12 SH3BP4 STK10 USP10 TBC1D4 MYPN NAV2 PLA2G4A RPRD2 MARK2 DDX24 PALLD

1.56e-125031561916964243
Pubmed

A human MAP kinase interactome.

SYNPO2 SETX CCDC186 APC RAP1GAP2 LAMA3 WNK1 DCTN1 GAB2 SH3BP4 NAV2 TNK2 BAIAP2 TNS1 SOS1

6.08e-094861561520936779
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ATP6V1B2 ZNF609 MYO1D FXR2 NT5E GART APC CLASP2 MED1 DCTN1 TRIP12 AHDC1 SH3BP4 USP10 TBC1D4 ZNF608 SIPA1L1 AHR DLAT MLLT6 MARK2 DDX24 ATP5F1B

9.55e-0912471562327684187
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

EPS15 SYNPO2 ZNF609 SCAMP3 KDM5D WNK1 TRIP12 SH3BP4 STK10 BUB1 ATF7IP2 TNK2 MLLT6 SOS1

1.02e-084301561435044719
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 DIP2B SETX APC CLASP2 WNK1 ECT2 TRIP12 GAB2 SH3BP4 VPS13D TBC1D4 SIPA1L1 NAV2 BAIAP2 MARK2 PAN3 PALLD WNK3

1.26e-088611561936931259
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

A2M DIP2B ZNF609 SETX DOCK10 APC PEX1 BTAF1 ECT2 SH3BP4 FARP2 PRKAA1 BUB1 DBR1 MARK2 PALLD

4.37e-086501561638777146
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TANC2 LCA5 ZNF609 PITRM1 CDH23 CLASP2 SCAMP3 MED1 WNK1 ECT2 DCTN1 GAB2 SH3BP4 TBC1D4 SIPA1L1 PTPRQ BUB1 TTI1 BAIAP2 MARK2 PAN3 DDX24

1.23e-0713211562227173435
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

COL17A1 CACHD1 TRIP12 VPS13D TBC1D4 SIPA1L1 CNTNAP2 PDZD2

1.40e-07130156812421765
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 ZNF609 SPAM1 ATXN7L2 FXR2 BCL7B PEX1 HIC2 C2CD5 SETD2 FAT1 ZFHX4 ZNF608 FAM120C SIPA1L1 AHR DLAT DDX24 SENP7 SOS1

1.53e-0711161562031753913
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TBC1D19 DIP2B EPS15 MBTPS1 ZNF609 PCDHGB1 INPP4A LAMA3 CLASP2 BTAF1 AHDC1 SH3BP4 FARP2 STK10 USP10 TBC1D4 ZNF608 FAM120C TNK2 RPRD2 BAIAP2 PAN3 PDZD2

2.34e-0714891562328611215
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 FAT4 SETX FXR2 DNAH2 HIC2 ZNF831 ECT2 TRIP12 FRY TBC1D4 FAM120C PKD1 FBXO43 AHR TMEM200C

2.34e-077361561629676528
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DIP2B BTAF1 MED1 POLA2 TRIP12 C2CD5 STK10 USP10 SETD2 TBC1D4 SIPA1L1 PLA2G4A MARK2 DDX24 SOS1

2.35e-067741561515302935
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

TANC2 ATP6V1B2 APC NCAM1 C2CD5 FAM163B SIPA1L1 BAIAP2 MARK2 SOS1

4.15e-063471561017114649
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TANC2 APC CLASP2 WNK1 C2CD5 USP10 VIPAS39 TBC1D4 SIPA1L1 BAIAP2 MARK2

6.00e-064461561124255178
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 DIP2B EPS15 FXR2 APC NCAM1 CLASP2 DCTN1 CACNG2 USP10 FRY FAM120C SIPA1L1 BAIAP2 TNS1 WNK3

7.53e-069631561628671696
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MBTPS1 ZNF609 PITRM1 INPP4A HIC2 CLASP2 MED1 HSD11B1L POLA2 WNK1 DCTN1 PREX2 C2CD5 USP10 SETD2 AHR DLAT SEC63 SOS1

8.51e-0613271561932694731
Pubmed

Genetic linkage analysis and homology relationships of genes located on human chromosome 11q.

NCAM1 PGR MS4A1

1.04e-051015631679745
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

A2M TANC2 DIP2B INPP4A APC CLASP2 PREX2 USP10 FRY FAM120C SIPA1L1

1.08e-054751561131040226
Pubmed

A mouse model for endometrioid ovarian cancer arising from the distal oviduct.

APC PGR

2.00e-052156224474556
Pubmed

Akkermansia muciniphila inhibits tryptophan metabolism via the AhR/β-catenin signaling pathway to counter the progression of colorectal cancer.

APC AHR

2.00e-052156237781044
Pubmed

Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.

APC SETD2

2.00e-052156228825595
Pubmed

Reciprocal regulation of Rag expression in thymocytes by the zinc-finger proteins, Zfp608 and Zfp609.

ZNF609 ZNF608

2.00e-052156223076336
Pubmed

Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease.

EFNA2 BAIAP2

2.00e-052156234523824
Pubmed

Suppression of intestinal polyposis in Apc(delta 716) knockout mice by an additional mutation in the cytosolic phospholipase A(2) gene.

APC PLA2G4A

2.00e-052156210969066
Pubmed

Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.

ERVV-2 ERVV-1

2.00e-052156218826608
Pubmed

Regulation of Na+-K+-Cl- cotransporter type 2 by the with no lysine kinase-dependent signaling pathway.

WNK1 WNK3

2.00e-052156230917032
Pubmed

MARK2 inhibits the growth of HeLa cells through AMPK and reverses epithelial-mesenchymal transition.

PRKAA1 MARK2

2.00e-052156228560405
Pubmed

Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.

ERVV-2 ERVV-1

2.00e-052156223555306
Pubmed

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells.

CDH23 USH2A

2.00e-052156217360538
Pubmed

Integrated Analysis of ECT2 and COL17A1 as Potential Biomarkers for Pancreatic Cancer.

COL17A1 ECT2

2.00e-052156235722628
Pubmed

Intestinal tumorigenesis is not affected by progesterone signaling in rodent models.

APC PGR

2.00e-052156221818351
Pubmed

Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner.

DCTN1 MREG

2.00e-052156223523350
Pubmed

CD56bright cells increase expression of {alpha}4 integrin at ovulation in fertile cycles.

NCAM1 ITGA4

2.00e-052156218628406
Pubmed

Induction of cardiac angiogenesis requires killer cell lectin-like receptor 1 and α4β7 integrin expression by NK cells.

ITGA4 KLRG1

2.00e-052156220971926
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

EPS15 ZNF609 INPP4A APC DCTN1 TBC1D4 ZFHX4 ZNF608 BUB1 ATF7IP2

2.08e-054181561034709266
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

TANC2 GAB2 TBC1D4 BAIAP2 MARK2 ATP5F1B

3.04e-05132156616944949
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SETX APC PEX1 CLASP2 ITGA9 WNK1 DCTN1 TRIP12 C2CD5 ESCO2 SIPA1L1 MYPN PRKAA1 PAN3 SEC63 TNS1

3.19e-0510841561611544199
Pubmed

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.

SLC9A9 ABCB5 RAP1GAP2 NCAM1 MYPN KCNMB3

3.31e-05134156624324551
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

FXR2 CDH23 CLASP2 ECT2 TRIP12 FAT1 ZFHX4 DBR1 PALLD

3.96e-05361156926167880
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

APC CLASP2 VPS13D TBC1D4 SIPA1L1 MYPN PALLD

4.68e-05209156736779422
Pubmed

Modifier genes in mice and humans.

APC MREG PLA2G4A

4.75e-0516156311256068
Pubmed

Modifier genes and protective alleles in humans and mice.

APC CDH23 PLA2G4A

4.75e-0516156312787792
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

CDH23 PTPRQ USH2A

4.75e-0516156317567809
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EPS15 FAT4 SETX CCDC186 APC NCAM1 CLASP2 TRIP12 GAB2 SH3BP4 FAT1 VIPAS39 BAIAP2

5.21e-057771561335844135
Pubmed

The Med1 subunit of the mediator complex induces liver cell proliferation and is phosphorylated by AMP kinase.

MED1 PRKAA1

5.98e-053156223943624
Pubmed

USP10 suppresses tumor progression by inhibiting mTOR activation in hepatocellular carcinoma.

USP10 PRKAA1

5.98e-053156230056112
Pubmed

The role of PGE2 in intestinal inflammation and tumorigenesis.

APC PLA2G4A

5.98e-053156225460828
Pubmed

AHR/TET2/NT5E axis downregulation is associated with the risk of systemic lupus erythematosus and its progression.

NT5E AHR

5.98e-053156236314527
Pubmed

AMPK is required for uterine receptivity and normal responses to steroid hormones.

PGR PRKAA1

5.98e-053156232191914
Pubmed

Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis.

APC BUB1

5.98e-053156217227893
Pubmed

SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways.

SETD2 PRKAA1

5.98e-053156232619406
Pubmed

Rho GTPase Cdc42 is a direct interacting partner of Adenomatous Polyposis Coli protein and can alter its cellular localization.

APC BAIAP2

5.98e-053156221311754
Pubmed

Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells.

CDH23 PKD1

5.98e-053156221865467
Pubmed

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis.

APC PLA2G4A

5.98e-053156211274413
Pubmed

SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization.

APC SH3BP4

5.98e-053156230811977
Pubmed

A calcium-dependent phospholipase A2 (cPLA2) expression is regulated by MIG-6 during endometrial tumorigenesis.

PGR PLA2G4A

5.98e-053156230773264
Pubmed

Osteopontin mediates macrophage chemotaxis via α4 and α9 integrins and survival via the α4 integrin.

ITGA4 ITGA9

5.98e-053156223192608
Pubmed

ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice.

APC AHR

5.98e-053156223455376
Pubmed

PAR-1 and the microtubule-associated proteins CLASP2 and dynactin-p50 have specific localisation on mouse meiotic and first mitotic spindles.

CLASP2 MARK2

5.98e-053156216123238
Pubmed

A functional role for AMPK in female fertility and endometrial regeneration.

PGR PRKAA1

5.98e-053156230328345
Pubmed

Deubiquitination and Activation of AMPK by USP10.

USP10 PRKAA1

5.98e-053156226876938
Pubmed

Regulation of cell migration by α4 and α9 integrins.

ITGA4 ITGA9

5.98e-053156230819933
Pubmed

Autism-associated familial microdeletion of Xp11.22.

FAM120C WNK3

5.98e-053156218498374
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TANC2 EPS15 RAP1GAP2 CLASP2 POLA2 WNK1 GAB2 FARP2 STK10 SETD2 MYPN AHR RPRD2 DBR1 PAN3

7.22e-0510381561526673895
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DOCK10 HIC2 WNK1 ZNF608 SIPA1L1 NAV2 RPRD2

7.44e-05225156712168954
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TANC2 ATP6V1B2 MYO1D INPP4A APC NCAM1 CLASP2 DCTN1 USP10 C12orf50 FAM120C SIPA1L1 PRKAA1 DLAT BAIAP2 MARK2 TNS1 ATP5F1B

8.02e-0514311561837142655
Pubmed

IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.

NCAM1 ITGA4 ITGA9

9.54e-0520156322687584
Pubmed

Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.

SLC9A9 ST8SIA1 PALLD

1.11e-0421156320708005
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ZNF609 MYO1D FXR2 APC MED1 TRIP12 USP10 FAM120C PRKAA1 BAIAP2 DDX24 PALLD

1.11e-047241561236232890
Pubmed

The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase.

APC BUB1

1.19e-04415629660858
Pubmed

Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex.

WNK1 TBC1D4

1.19e-044156220937822
Pubmed

A role for the Adenomatous Polyposis Coli protein in chromosome segregation.

APC BUB1

1.19e-044156211283619
Pubmed

WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.

WNK1 WNK3

1.19e-044156211571656
Pubmed

Human hypertension caused by mutations in WNK kinases.

WNK1 WNK3

1.19e-044156211498583
Pubmed

SLC26A9 is a Cl(-) channel regulated by the WNK kinases.

WNK1 WNK3

1.19e-044156217673510
Pubmed

Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.

WNK1 WNK3

1.19e-044156234384519
Pubmed

The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1.

ITGA4 ITGA9

1.19e-044156235802072
Pubmed

Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes.

BAIAP2 MARK2

1.19e-044156224165937
Pubmed

WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1.

WNK1 TBC1D4

1.19e-044156231816312
Pubmed

Interaction of nebulin SH3 domain with titin PEVK and myopalladin: implications for the signaling and assembly role of titin and nebulin.

MYPN SOS1

1.19e-044156212482578
Pubmed

Type XVII collagen (BP180) can function as a cell-matrix adhesion molecule via binding to laminin 332.

COL17A1 LAMA3

1.19e-044156221034821
Pubmed

A neurogenomics approach to gene expression analysis in the developing brain.

CCDC186 NCAM1 WNK1 TRIP12 PKD1 ATP5F1B

1.24e-04170156615582152
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

EPS15 ZNF609 FXR2 APC CLASP2 WNK1 FARP2 SETD2 VIPAS39 RPRD2 BAIAP2 SEC63

1.25e-047331561234672954
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EPS15 ATP6V1B2 SETX NT5E APC CLASP2 MED1 ECT2 AHDC1 FARP2 USP10 SETD2 FAM120C SIPA1L1 BAIAP2 MARK2 SEC63 ATP5F1B

1.41e-0414971561831527615
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 RAP1GAP2 CLASP2 BTAF1 WNK1 DCTN1 AHDC1 SH3BP4 STK10 FAT1 EFNA2 PKD1 NAV2 TNK2 MLLT6

1.43e-0411051561535748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF609 SETX PITRM1 HIC2 CACHD1 USP10 ZNF608 CNTNAP2 NAV2 RPRD2

1.47e-045291561014621295
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

EPS15 ATP6V1B2 FXR2 APC FAM120C SIPA1L1 TNK2 BAIAP2 MARK2

1.50e-04430156932581705
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

A2M SETX FXR2 BCL7B CLASP2 MED1 TRIP12 ESCO2 USP10 FAM120C AHR DLAT BAIAP2 DBR1 MARK2 SEC63 ATP5F1B

1.52e-0413711561736244648
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

BNC2 POLA2 AHDC1 SH3BP4 MREG VPS13D SIPA1L1 TTI1 MARK2 SOS1

1.64e-045361561015840001
Pubmed

Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.

FAT4 NCAM1 FAT1

1.67e-0424156326116661
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

BNC2 POLA2 AHDC1 SH3BP4 MREG VPS13D SIPA1L1 TTI1 MARK2 SOS1

1.69e-045381561010512203
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

CDH23 HIC2 POLA2 USP10 SETD2 NAV2 DCAF4

1.69e-04257156730945288
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

A2M COL17A1 MYO1D FXR2 GART LAMA3 ITGA4 ECT2 TRIP12 USP10 SIPA1L1 BAIAP2 MARK2 SEC63 DDX24 ATP5F1B

1.78e-0412571561636526897
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

ATXN7L2 FXR2 APC CLASP2 POLA2 TRIP12 USP10 SIPA1L1 SASS6 MARK2 PAN3 DDX24 TARBP1 DCAF4

1.85e-0410051561419615732
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

EPS15 SP2 ZNF609 SETX MED1 AHDC1 USP10 ZNF608 PALLD

1.90e-04444156934795231
Pubmed

Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.

APC DCTN1

1.98e-045156212388762
Pubmed

A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation.

PKD1 SEC63

1.98e-045156221685914
Pubmed

Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.

APC CLASP2

1.98e-045156217113391
Pubmed

Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III.

NCAM1 ST8SIA1

1.98e-045156210766765
Pubmed

Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.

WNK1 WNK3

1.98e-045156224641320
InteractionYWHAH interactions

TANC2 LCA5 DIP2B SETX FXR2 APC CLASP2 MED1 POLA2 WNK1 ECT2 DCTN1 TRIP12 GAB2 SH3BP4 VPS13D TBC1D4 MS4A1 SIPA1L1 PRKAA1 NAV2 BAIAP2 MARK2 PAN3 PALLD WNK3

2.06e-07110215226int:YWHAH
InteractionYWHAZ interactions

TANC2 LCA5 SYNPO2 APC RAP1GAP2 CLASP2 ITGA4 WNK1 ECT2 DCTN1 TRIP12 GAB2 SH3BP4 VPS13D TBC1D4 MS4A1 SIPA1L1 PRKAA1 NAV2 DLAT TNK2 BAIAP2 MARK2 DDX24 TNS1 SENP7 ATP5F1B

1.86e-06131915227int:YWHAZ
InteractionYWHAB interactions

TANC2 LCA5 APC NCAM1 CLASP2 ITGA4 WNK1 ECT2 DCTN1 TRIP12 GAB2 SH3BP4 VPS13D VIPAS39 TBC1D4 MS4A1 SIPA1L1 PRKAA1 NAV2 PRMT9 BAIAP2 MARK2 DDX24

2.22e-06101415223int:YWHAB
GeneFamilyCadherin related

FAT4 CDH23 FAT1

8.50e-051793324
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ECT2 PREX2 FARP2 SOS1

3.71e-0466934722
GeneFamilyZinc fingers C2H2-type|Sp transcription factors

SP2 SP9

9.20e-049932755
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

MYO1D APC WNK1 PREX2 TNS1

2.43e-03181935694
GeneFamilyF-type ATPases|Mitochondrial complex V: ATP synthase subunits

ATP5MC1 ATP5F1B

3.80e-0318932416
GeneFamilyCD molecules|Integrin alpha subunits

ITGA4 ITGA9

3.80e-03189321160
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCZ1 PLA2G4A

4.23e-0319932832
GeneFamilyF-type ATPases|Mitochondrial complex V: ATP synthase subunits

ATP5MC1 ATP5F1B

4.23e-0319932644
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_UP

RSPH4A PEX1 MMACHC NAV2 SASS6 TTI1 C2CD6 DBR1

1.96e-051971518M4257
CoexpressionGSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN

EVI2B NCAM1 ITGA9 C2CD5 EFNA2 DLAT PLA2G4A KLRG1

2.11e-051991518M8367
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

TANC2 DIP2B INPP4A CCDC186 APC RAP1GAP2 PEX1 LAMA3 NCAM1 AHDC1 C2CD5 CACNG2 FRY ZFHX4 CNTNAP2 TNK2 C2CD6 TARBP1 WNK3

2.11e-05110615119M39071
CoexpressionGSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN

LCA5 MBTPS1 NT5E CCDC186 BCL7B ST8SIA1 ZDHHC20 PKD1

2.18e-052001518M9765
CoexpressionLAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES

A2M SYNPO2 MYO1D FRY PAN3 TNS1 PALLD

3.34e-051551517M39246
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

EPS15 ZNF609 SETX INPP4A DOCK10 EVI2B BTAF1 ITGA4 MED1 ZNF831 WNK1 TRIP12 EPG5 STK10 SETD2 TBC1D4 AHR TNK2 MLLT6 DDX24 SENP7 SOS1

4.66e-05149215122M40023
CoexpressionFAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON

RAP1GAP2 HIC2 PKD1 FAM227A TNK2 TARBP1 PDZD2

5.17e-051661517M39026
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TANC2 MYO1D DACT2 LAMA3 ITGA9 NAV2 PLA2G4A BAIAP2

2.63e-071841548ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAT4 SYNPO2 NCAM1 ST8SIA1 NAV2 PLA2G4A PALLD

3.23e-071891548c734e5693808a0333139e87bd5be2597a9252afe
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO1D LAMA3 PTPRQ ATF7IP2 NAV2 TNS1 PALLD PDZD2

3.36e-07190154830b50d183d7649146eb1e79b47ba897355f1998a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAT4 SYNPO2 NCAM1 ST8SIA1 NAV2 PLA2G4A PALLD

3.50e-071911548c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAT4 SYNPO2 NCAM1 ST8SIA1 NAV2 PLA2G4A PALLD

3.50e-071911548cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 INPP4A DOCK10 RAP1GAP2 NCAM1 ZNF831 STK10 KLRG1

3.50e-0719115486345c1aa0fd2f9f2154a44f9393bf7c72bb1f44e
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 INPP4A DOCK10 RAP1GAP2 NCAM1 ITGA4 ZNF831 STK10

3.79e-0719315481cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 ZNF609 MYO1D SIPA1L1 NAV2 PAN3 PDZD2 SOS1

4.26e-071961548ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAT4 SYNPO2 NCAM1 ST8SIA1 PGR PLA2G4A PALLD

4.26e-071961548a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAT4 SYNPO2 NCAM1 ST8SIA1 PGR PLA2G4A PALLD

4.26e-0719615483e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M BNC2 SLC9A9 FAT4 SYNPO2 ITGA9 PREX2 NAV2

4.43e-0719715480dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 ZNF609 MYO1D GAB2 SIPA1L1 NAV2 PAN3 PDZD2

4.60e-0719815481996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M INPP4A DOCK10 RAP1GAP2 ITGA4 ZNF831 STK10 KLRG1

4.78e-071991548eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT4 DOCK10 PREX2 FAT1 ZFHX4 ZNF608 CNTNAP2 MEGF11

4.96e-072001548d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M BNC2 SLC9A9 FAT4 ST8SIA1 PREX2 PGR NAV2

4.96e-0720015483dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

A2M FAT4 SETX INPP4A NCAM1 MLLT6 KLRG1 PALLD

4.96e-0720015482281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellControl-NK|World / Disease group and Cell class

A2M TANC2 PCDHGA5 NCAM1 CACHD1 SH3BP4 NAV2

6.80e-071431547fe08adc9472dfd4242497d6c614d0490713261da
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

MYO1D LAMA3 MMACHC SETD2 MALRD1 C12orf50 KCNMB3

7.46e-07145154780684ec249fa445c1b35f94608a4a6824d53f2d9
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

MYO1D LAMA3 MMACHC SETD2 MALRD1 C12orf50 KCNMB3

7.46e-071451547cb534333fba44b241b14fb0d7b74e843f4e7f9f8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB5 DNAH2 DOCK10 CDH23 FAT1 SP9 TMEM200C

3.16e-061801547392bc71a69653ba12de31bed4e9357f181094641
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M BNC2 FAT4 SYNPO2 ITGA9 PGR PALLD

3.16e-06180154701f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

INPP4A DOCK10 RAP1GAP2 NCAM1 ITGA4 ZNF831 STK10

3.28e-0618115478906ee8a7a1616dfe8c3b5c73988416641213629
ToppCellSevere-Myeloid-mDC|Severe / Condition, Lineage, Cell class and cell subclass

A2M ITGA4 PREX2 PGR MREG TBC1D4 PALLD

3.28e-06181154700f2949b609ac21bd2da6fd8f685739eeb2f48ad
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB5 DNAH2 DOCK10 CDH23 FAT1 SP9 TMEM200C

3.28e-0618115478fd64404e57c22c204d835fc5626f73554257b19
ToppCellSevere-Myeloid-mDC-|Severe / Condition, Lineage, Cell class and cell subclass

A2M ITGA4 PREX2 PGR MREG TBC1D4 PALLD

3.28e-06181154751ded98c76ec35ab1d24ac3ab98280381daa9831
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAM1 FRY PKD1 AHR SASS6 PRMT9 DCAF4

3.52e-0618315473ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M MGAM FAT4 FAT1 ZFHX4 PTPRQ USH2A

3.65e-0618415472cbed6462fea2622871bb7e49b0df3d984239281
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1D LAMA3 PTPRQ ATF7IP2 NAV2 TNS1 PDZD2

3.65e-06184154757c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M MGAM FAT4 FAT1 ZFHX4 PTPRQ USH2A

3.65e-061841547ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M MGAM FAT4 FAT1 ZFHX4 PTPRQ USH2A

3.65e-0618415472b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

SYNPO2 NCAM1 FRY TBC1D4 MYPN PALLD PDZD2

3.65e-061841547ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1D LAMA3 PTPRQ ATF7IP2 NAV2 TNS1 PDZD2

3.65e-061841547d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

A2M DOCK10 ST8SIA1 ITGA4 ZNF831 STK10 KLRG1

3.78e-06185154702ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SLC9A9 SYNPO2 PGR STK10 ZFHX4 DCAF4

3.78e-061851547e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SLC9A9 SYNPO2 PGR STK10 ZFHX4 DCAF4

3.78e-0618515479d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

SYNPO2 NCAM1 FRY TBC1D4 MYPN PALLD PDZD2

3.78e-0618515476baccb26f999145e51b91d94315bf8d4655bef31
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

INPP4A DOCK10 RAP1GAP2 NCAM1 ITGA4 ZNF831 STK10

3.78e-061851547755c0998c729f462399f1d5e88adf4bfae31be30
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TANC2 DACT2 LAMA3 ITGA9 NAV2 PLA2G4A BAIAP2

3.92e-061861547e83718fabb057100835d3357df407f283d23fe16
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

ATP6V1B2 RAP1GAP2 PGR CACNG2 MREG CNTNAP2 DDX24

4.06e-06187154761b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

A2M SYNPO2 MYO1D DOCK10 LAMA3 CLASP2 FRY

4.21e-06188154734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 NCAM1 ITGA9 FRY MYPN PALLD PDZD2

4.51e-061901547918ad5037881212008f9f69d5df5da91fd01422c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAT4 SYNPO2 NCAM1 ST8SIA1 PLA2G4A PALLD

4.51e-0619015472e592323085ba9c019d678ac2a784462ab470ed9
ToppCellCOVID-19-kidney-NK|kidney / Disease (COVID-19 only), tissue and cell type

INPP4A DOCK10 EVI2B NCAM1 ITGA4 ZNF831 STK10

4.51e-061901547e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAT4 SYNPO2 NCAM1 ST8SIA1 PLA2G4A PALLD

4.51e-061901547445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SYNPO2 NCAM1 ST8SIA1 PGR PLA2G4A PALLD

4.67e-061911547a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

TANC2 BNC2 SLC9A9 DOCK10 ITGA4 GAB2 STK10

4.67e-0619115473b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SYNPO2 NCAM1 ST8SIA1 NAV2 PLA2G4A PALLD

4.67e-061911547806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SYNPO2 ITGA9 PGR NAV2 PLA2G4A PALLD

4.67e-06191154739092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA3 CACHD1 MREG ZNF608 PTPRQ NAV2 PDZD2

4.67e-061911547ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SYNPO2 ITGA9 PGR NAV2 PLA2G4A PALLD

4.67e-061911547ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 ABCB5 DOCK10 LAMA3 PREX2 ZNF608 TMEM200C

4.83e-0619215473abee376c37c3646da33ac381aa63d50a01607a6
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

MYO1D CACHD1 ITGA9 FAT1 ZNF608 AHR NAV2

4.83e-061921547d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

A2M BNC2 FAT4 SYNPO2 NCAM1 ITGA9 FAT1

4.83e-06192154772881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

ABCB5 MYRFL SH3BP4 FRY AHR NAV2 PDZD2

4.83e-061921547e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 MYRFL PREX2 FAT1 ZNF608 CNTNAP2 SP9

4.83e-06192154767d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNPO2 ST8SIA1 ITGA4 MREG TBC1D4 ZNF608 PALLD

5.00e-0619315477426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNPO2 ST8SIA1 ITGA4 MREG TBC1D4 ZNF608 PALLD

5.00e-061931547a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCellnucseq-Immune-Immune_Myeloid-pMON-pMON|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC9A9 INPP4A RAP1GAP2 CDH23 ITGA4 STK10 SIPA1L1

5.17e-061941547e237384b02be460d44eeada3026a5691c66f6fc1
ToppCellnucseq-Immune-Immune_Myeloid-pMON|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC9A9 INPP4A RAP1GAP2 CDH23 ITGA4 STK10 SIPA1L1

5.17e-0619415470bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

NCAM1 FRY TBC1D4 ZNF608 MYPN PALLD PDZD2

5.17e-061941547c3535f7cc0076653c72db582047cff053c322397
ToppCellCOVID-19-lung-NK/NKT|lung / Disease (COVID-19 only), tissue and cell type

BNC2 DOCK10 RAP1GAP2 NCAM1 ITGA4 ZNF831 STK10

5.35e-0619515473ab941a369e3815f338890b116dc77aefa054098
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SYNPO2 NCAM1 ST8SIA1 PGR PLA2G4A PALLD

5.53e-061961547ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SYNPO2 NCAM1 ST8SIA1 PGR PLA2G4A PALLD

5.53e-06196154730ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SYNPO2 COL17A1 LAMA3 FAT1 NAV2 TNS1

5.72e-061971547f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TANC2 DACT2 LAMA3 FAT1 NAV2 PLA2G4A BAIAP2

5.91e-061981547285f729140b1df029c24f6ca1d2438470ac51794
ToppCellCOVID-19-Myeloid-Migratory_DC|Myeloid / Condition, Lineage and Cell class

SYNPO2 ST8SIA1 ITGA4 MREG TBC1D4 ZNF608 PALLD

5.91e-06198154790f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 DOCK10 RAP1GAP2 ST8SIA1 ITGA9 PLA2G4A WNK3

6.31e-0620015479156f8fd61a833891d2f7b7fadd693b81b1e2d5a
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 DOCK10 RAP1GAP2 ST8SIA1 ITGA9 PLA2G4A WNK3

6.31e-062001547566fe2e78e6f35399ec6aad5964f6d4d8ade82c6
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

DOCK10 LAMA3 PREX2 FAT1 ZFHX4 ZNF608 MEGF11

6.31e-062001547862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

DOCK10 LAMA3 PREX2 FAT1 ZFHX4 ZNF608 MEGF11

6.31e-062001547a91345f268f13170c27309333603eb82400c9947
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

DOCK10 LAMA3 PREX2 FAT1 ZFHX4 ZNF608 MEGF11

6.31e-062001547d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

A2M INPP4A NCAM1 ZNF831 STK10 MLLT6 KLRG1

6.31e-062001547f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASIC5 MYPN PTPRQ BUB1 C2CD6 USH2A

1.15e-05145154696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 DOCK10 ECT2 GAB2 STK10 SIPA1L1

2.22e-0516315468dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 DOCK10 ECT2 GAB2 STK10 SIPA1L1

2.22e-051631546fd243ca223079033be480a24817a399f281fa4d4
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF9 DOCK10 ITGA4 MREG TBC1D4 MS4A1

2.38e-0516515468a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2B MYRFL ZNF831 ZNF608 MS4A1 PAN3

2.46e-0516615466a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2B MYRFL ZNF831 ZNF608 MS4A1 PAN3

2.46e-0516615468d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

DACT2 RAP1GAP2 ST8SIA1 PGR CACNG2 SKOR1

2.55e-0516715469efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

DACT2 RAP1GAP2 ST8SIA1 PGR CACNG2 SKOR1

2.55e-051671546904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TANC2 NCAM1 FARP2 FRY ZNF608 PLA2G4A

2.64e-0516815468072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ST8SIA1 ITGA4 FRY SIGLEC10 UGT2B11 C13orf42

3.01e-0517215463a76cfb2832790144a6da6406469ead0767916b5
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M BNC2 FAT4 SYNPO2 ITGA9 PGR

3.11e-0517315461f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPAM1 ITGA4 ESCO2 BUB1 SIGLEC10 FBXO43

3.21e-0517415467b318796728001c17b4043d2b033330c7be40c78
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

A2M FAT4 NCAM1 FAT1 NAV2 PALLD

3.21e-051741546430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

LAMA3 PTPRQ ATF7IP2 NAV2 TNS1 PDZD2

3.21e-051741546548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 SYNPO2 PGR NAV2 TNS1 PALLD

3.31e-0517515461799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ATXN7L2 CACHD1 MYRFL ITGA9 ESCO2 PTPRQ

3.53e-05177154675cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA3 ITGA9 PTPRQ NAV2 BAIAP2 WNK3

3.53e-0517715469af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB5 DOCK10 CDH23 OPN1SW SP9 TMEM200C

3.65e-05178154608b4a497aca0aeabf4f6a8a55c05b56417b69e78
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M SYNPO2 ZFHX4 NAV2 PLA2G4A PALLD

3.65e-051781546d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ZNF609 ITGA4 FRY SIGLEC10 UGT2B11 KLRG1

3.76e-051791546810972561d1ae5a68389b54ceeac7a49890513a4
ToppCellLV|World / Chamber and Cluster_Paper

SYNPO2 NCAM1 ITGA9 TBC1D4 C2CD6 PDZD2

3.88e-0518015465ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BNC2 SYNPO2 NCAM1 ITGA9 FAT1 TMEM200C

4.00e-05181154625915e2500430a902db37d79a749ce2990b69810
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SYNPO2 NCAM1 ITGA4 TBX18 ZFHX4 PLA2G4A

4.00e-0518115469b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1D LAMA3 ITGA9 PTPRQ NAV2 BAIAP2

4.00e-051811546b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 LAMA3 FRY FAT1 ZNF608 PALLD

4.00e-0518115465f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M BNC2 ST8SIA1 PREX2 C2CD6 PALLD

4.00e-0518115469ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 LAMA3 FRY FAT1 ZNF608 PALLD

4.00e-051811546c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH2 LAMA3 ZFHX4 PTPRQ BAIAP2

4.03e-051101545c80d1c3df75648e2c8f6832279c2acca63d76681
DrugAC1N5XY5

NT5E APC ECT2 FARP2 SETD2

4.61e-07241515CID004251231
Diseaseautism spectrum disorder (is_implicated_in)

ITGA4 CNTNAP2 BAIAP2

7.01e-05161513DOID:0060041 (is_implicated_in)
DiseaseAdenocarcinoma of lung (disorder)

GART APC WNK1 MS4A1 AHR TNK2 SOS1

9.64e-052061517C0152013
DiseaseAmyotrophic Lateral Sclerosis

SETX DCTN1 PLA2G4A DBR1

2.26e-04581514C0002736
DiseaseAdult junctional epidermolysis bullosa (disorder)

COL17A1 LAMA3

2.58e-0451512C0268374
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)

COL17A1 LAMA3

2.58e-0451512C2608084
DiseasePolycystic Kidney - body part

PKD1 SEC63

2.58e-0451512C1567435
Diseasejunctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)

COL17A1 LAMA3

2.58e-0451512DOID:0060738 (implicated_via_orthology)
Diseasepancreatic cancer (is_implicated_in)

APC NCAM1 ITGA4 ITGA9 PALLD

2.84e-041121515DOID:1793 (is_implicated_in)
Diseaseretinitis pigmentosa (implicated_via_orthology)

DACT2 EPG5 USH2A

3.51e-04271513DOID:10584 (implicated_via_orthology)
Diseasepseudohypoaldosteronism (implicated_via_orthology)

WNK1 WNK3

3.85e-0461512DOID:4479 (implicated_via_orthology)
DiseaseJunctional Epidermolysis Bullosa

COL17A1 LAMA3

3.85e-0461512C0079301
DiseasePolycystic Kidney Diseases

PKD1 SEC63

3.85e-0461512C0022680
DiseaseAutistic Disorder

SLC9A9 MYO1D APC ITGA4 FARP2 CNTNAP2 PLA2G4A

4.09e-042611517C0004352
Diseasejunctional epidermolysis bullosa (is_implicated_in)

COL17A1 LAMA3

5.37e-0471512DOID:3209 (is_implicated_in)
Diseasepolycystic liver disease (implicated_via_orthology)

PKD1 SEC63

5.37e-0471512DOID:0050770 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

SLC9A9 FXR2 SCAMP3 KDM5D CNTNAP2

1.14e-031521515DOID:0060041 (implicated_via_orthology)
Diseaseresponse to methotrexate, serum alanine aminotransferase measurement

RAP1GAP2 CACHD1 PDZD2

1.40e-03431513EFO_0004735, GO_0031427
DiseaseS-warfarin to R-warfarin ratio measurement

SLC9A9 DACT2 RAP1GAP2 STPG1

1.46e-03951514EFO_0803331
DiseaseAmelogenesis Imperfecta

COL17A1 PEX1

1.66e-03121512C0002452
Diseaseovarian serous carcinoma

BNC2 GALK2 LAMA3

1.70e-03461513EFO_1001516
DiseaseMalignant neoplasm of pancreas

APC BUB1 AHR PALLD

1.90e-031021514C0346647
DiseaseWeight Gain

VPS13D SIPA1L1 AHR PALLD

1.90e-031021514C0043094
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

CDH23 PTPRQ

1.96e-03131512C1846647
Diseaseattempted suicide

NCAM1 ESCO2 TBX18 ATF7IP2 KCNMB3

2.27e-031781515EFO_0004321
Diseasecaffeine measurement

AHR MEGF11

2.61e-03151512EFO_0021177
Diseasefactor VII activating protease measurement

ZNF609 USP10 MALRD1

2.84e-03551513EFO_0009368
DiseaseAmyotrophic lateral sclerosis

SETX DCTN1

3.36e-03171512cv:C0002736
Diseaserespiratory symptom change measurement, response to placebo

ATF7IP2 NAV2

3.36e-03171512EFO_0008344, EFO_0010068
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

DIP2B SETD2

3.36e-03171512DOID:0060307 (is_implicated_in)
Diseasecolorectal cancer (is_implicated_in)

APC SETD2 FAT1 BUB1

3.52e-031211514DOID:9256 (is_implicated_in)
Diseasedisease free survival

CCDC168 CNTNAP2

3.77e-03181512EFO_0000409
Diseasedisease progression measurement

CDH23 ATF7IP2 UGT2B11

3.81e-03611513EFO_0008336
DiseasePR interval

EPS15 ABCB5 RAP1GAP2 ITGA9 FAT1 SIPA1L1 NAV2 KCNMB3

4.09e-034951518EFO_0004462
Diseasecerebral infarction (is_marker_for)

A2M SOS1

4.20e-03191512DOID:3526 (is_marker_for)
DiseaseCardiomyopathies

EPG5 MYPN GAA SOS1

4.55e-031301514C0878544
Diseasealpha-tocopherol measurement

USH2A SOS1

4.65e-03201512EFO_0007898
Diseaseage at menopause

MGAM DOCK10 GAB2 PGR ZFHX4 DCAF4

4.73e-033021516EFO_0004704
Diseasebitter alcoholic beverage consumption measurement

MGAM DNAH2 CNTNAP2 SENP7

4.93e-031331514EFO_0010092

Protein segments in the cluster

PeptideGeneStartEntry
QDSLSKSPFIPSDYQ

AHR

586

P35869
NSSPEYPRKEFASSS

COL17A1

116

Q9UMD9
KFYHPQSSSANSPSE

FAM227A

341

F5H4B4
LSESAPQSNFSYTQP

EPG5

151

Q9HCE0
YPASKADIPSVAFSS

DCAF4

456

Q8WV16
VSSLQSSPDFSAFPK

MLLT6

346

P55198
TFPESANEKTYSESP

CCDC186

126

Q7Z3E2
TNVKFQSPAYSSVDT

PRMT9

331

Q6P2P2
LSGLSKPVSSYPNTF

BUB1

751

O43683
FKASEQIYGTPSSSP

DCTN1

871

Q14203
SSESEVSPTPYKNDQ

BNC2

366

Q6ZN30
FYSHSTPKEAASSSP

CASTOR1

206

Q8WTX7
VEFKNVSFNYPSRPS

ABCB5

386

Q2M3G0
HSPAPFSKSSTFYRN

FAT4

4701

Q6V0I7
SFSSPYEHLSQPETK

CACHD1

661

Q5VU97
SSPQRKTAAESPFYE

C13orf42

11

A0A1B0GVH6
LTPPFNQSSKTSFYF

ERVV-2

101

B6SEH9
SPQPSYAADANDSKA

AHDC1

596

Q5TGY3
PTSFSTPYSAAKFAL

HSD11B1L

171

Q7Z5J1
NPSEKNSPSTQYCYS

MS4A1

171

P11836
YQLKVDSSTNSSPSP

BCL7B

101

Q9BQE9
SIQPPNKFYSLNSTT

CDH23

816

Q9H251
RPQFSKPQFSTSVYE

CDH23

2506

Q9H251
SSKQPSYSNFPLQVA

ATP5MC1

36

P05496
APSSTFSVRAKQTYP

ATXN7L2

326

Q5T6C5
YAAQTSPSPKAGAAT

ATP5F1B

46

P06576
PTTQSFASDPKYATP

TNK2

816

Q07912
SFPLSSEPFQGSYKV

A2M

191

P01023
NTPESSINYGDTPKS

ECT2

421

Q9H8V3
NDNAPLFTPSEYSVS

PCDHGA5

236

Q9Y5G8
AARPDYIASKASPTS

INPP4A

476

Q96PE3
DPLKAATTPTATYNS

CACNG2

276

Q9Y698
ANSNPPEFTQTAYKA

FAT1

456

Q14517
SLNSSENPYATIKDP

MEGF11

936

A6BM72
FQLDSKPLYTPSSSF

LAMA3

3131

Q16787
NSYKPQASLSPSYID

MBTPS1

476

Q14703
SISSVLKDPDSNPYS

FXR2

506

P51116
VDPAISNNSSSSKPY

MGAM

451

O43451
SNNSSSSKPYGPYDR

MGAM

456

O43451
LKSSVYANAFPSTPV

MGAM

1021

O43451
NFDDAFLTYTTKPPS

KIAA1109

226

Q2LD37
PLRQSVQPSKFSSYS

KDM5D

196

Q9BY66
SEVAFSPKEYNSPSF

C2CD6

501

Q53TS8
LTPPFNQSSKTSFYF

ERVV-1

101

B6SEH8
FKNYTLDSSAAPTPQ

DLAT

176

P10515
PNQYFSLSTKESPDG

PCDHGB1

171

Q9Y5G3
AAAPPDYSKTRSASE

PDZD2

1296

O15018
TQPPKSFVYTFTQQS

EVI2B

136

P34910
AAYELKSYTESPTNP

FAM214A

1056

Q32MH5
KSYTESPTNPQFSPR

FAM214A

1061

Q32MH5
LANTNPLYPDFSTSA

GALK2

81

Q01415
TPAPSAAQTSAPSKY

DIP2B

71

Q9P265
YSASDSCSPPQVKGA

MYRFL

56

Q96LU7
YVPSFAKTSERSNPF

LCA5

556

Q86VQ0
FAVYLQPTSPSSSQK

OR1I1

256

O60431
ESSPSAYTQEAPQEK

MEIOSIN

401

C9JSJ3
SEEQKAYFSTPPAQR

MMACHC

216

Q9Y4U1
PDSAPENITYKNISS

PTPRQ

801

Q9UMZ3
SDPPKDVYYANLSSS

PTPRQ

991

Q9UMZ3
ESSSPDSGYLSPKNQ

PALLD

196

Q8WX93
ASQSPQYSFESLPQK

PGR

551

P06401
SSPSLLNDSAKPYSA

PAN3

191

Q58A45
ADSPPIVNSKYSTFR

FBXO43

51

Q4G163
DSKYSPSVKSPGAVF

ITGA9

71

Q13797
TYGSVPLSSNSPFKV

MALRD1

1851

Q5VYJ5
PEKTESSVYSFSNPL

MALRD1

2126

Q5VYJ5
DYGPQQKSSSSRPSC

KLRG1

21

Q96E93
SPSSKAQQTPSAQDY

DACT2

441

Q5SW24
TSLPPNYLSFQDSAS

DOCK10

811

Q96BY6
YTPTSASFVNKQPTL

BTAF1

176

O14981
ALYPTASTSFSQKSP

FAM163B

71

P0C2L3
SSASQFPNYLPSKAS

FAM120C

501

Q9NX05
EYPATISYSSFPSQK

ASIC5

381

Q9NY37
YCSSFKLFQASPSVP

BRF2

176

Q9HAW0
SSVNYEPSNPSEKGS

ATF7IP2

421

Q5U623
PSYPSYKLENLSSSE

GAA

131

P10253
PKSTVYPIFSASSVN

ESCO2

321

Q56NI9
QAAGPAIPTSNSYSK

MARK2

411

Q7KZI7
KAESPPRFYFSSNGT

ITGA4

526

P13612
YQLVSPAKNPSSLFS

DDX24

56

Q9GZR7
TLYEAPEPIFTSNNS

EFNA2

176

O43921
AISKVQPSSYAPQAT

IL22RA1

381

Q8N6P7
KNGTPFSCFYSPASQ

KCNMB3

181

Q9NPA1
FSVTAACYDPSKPQT

DBR1

341

Q9UK59
YHLPSSSDTLFNSPK

CNTNAP2

1136

Q9UHC6
EEPQIFYNASPSTLS

SPAM1

476

P38567
KEADPSNFANFSAYP

EPS15

836

P42566
CDNPPFYRFTASSKA

FRY

1511

Q5TBA9
KDLPATSPETFNYCT

CCDC168

1326

Q8NDH2
TPASPSSANAFYSLS

FARP2

396

O94887
TTKLSNPHYSPETSA

DNAH2

3486

Q9P225
IPKSFNYSPNSSTSE

RPRD2

586

Q5VT52
SSKPTALPSASSAYF

SASS6

636

Q6UVJ0
SPTEPKNYGSYSTQA

SCAMP3

76

O14828
FYSSTSPPQKFSRQN

CFAP47

1571

Q6ZTR5
KSQPPSIYNASATSV

PEX1

291

O43933
SGPSTPLKNQTYSFS

C2CD5

281

Q86YS7
SKSPAYTPQNLDSES

MED1

1451

Q15648
ASPYSPAKSFSASDE

PKD1

3456

P98161
SYPLSPLSDFATQDS

PLA2G4A

501

P47712
TIPSFFSKSACIYNP

OPN1SW

286

P03999
SVDYLALDFQPSSPS

GAB2

611

Q9UQC2
PAEPNFSTLLTAASY

HIC2

111

Q96JB3
GKTAASPQYSEPESS

RSPH4A

26

Q5TD94
SPNSKQELQPYSGSS

SKOR1

56

P84550
APKAHSYSPDSFNVS

USH2A

2246

O75445
PQSTLSEFYPRDSAK

ATP6V1B2

496

P21281
SQPSNTDAAKPTYTF

SENP7

701

Q9BQF6
KQEVFVYSPSPSSES

RAP1GAP2

671

Q684P5
TYSISIYSPKENPNA

SLC9A9

251

Q8IVB4
LSPFATTTKYPTFQD

SH3BP4

636

Q9P0V3
QSDDPSSSNKGYTPL

TMEM200C

526

A6NKL6
IYPKATRADSSNFNP

PLCZ1

406

Q86YW0
EKEPLVSDNNPYSSF

MREG

26

Q8N565
SFNNYDKSKPVTSPP

NAV2

311

Q8IVL1
SDYTLYPFSTQNPKD

PITRM1

141

Q5JRX3
NDVLFSSTYPSLPKS

SIPA1L1

1611

O43166
FGESKYFPSSSPVNI

SETX

1676

Q7Z333
TIDNSTYSLFPQATP

ST8SIA1

116

Q92185
FSPPSSISNIAFYNK

TANC2

1891

Q9HCD6
FSPSATPSQKYNSRS

POLA2

151

Q14181
QPTSKAYSPRYSISD

SOS1

1186

Q07889
KPVLPSYSDSSAAVA

SP9

261

P0CG40
YTSKETPFLSNPGTN

NT5E

176

P21589
NEAKDFYLATSPPDS

PRKAA1

346

Q13131
PPQSQSKLSDSYSNT

BAIAP2

326

Q9UQB8
VTPFNYNPSPRKSSA

APC

2781

P25054
YNPSPRKSSADSTSA

APC

2786

P25054
PNLSPDKYTSTSYND

C12orf50

371

Q8NA57
PYNYSDSISPFNKSA

CLASP2

1021

O75122
PSSNYSNIKIYNTPS

NCAM1

456

P13591
KSDQSASAPMSFYPQ

ZFHX4

176

Q86UP3
SPASPSKEFYLSNSE

ZDHHC20

76

Q5W0Z9
SPKQESASSSYFVAP

SYNPO2

1056

Q9UMS6
SASSSYFVAPRPKFS

SYNPO2

1061

Q9UMS6
PCSSEKNTDSQAPFY

SPEM3

546

A0A1B0GUW6
GYNFSTSPKLAASPE

TBX18

531

O95935
TAAYPTQSSIPFKSQ

STPG1

26

Q5TH74
TAAVSPSDYLQPAAS

SP2

11

Q02086
PSDYLQPAASTTQDS

SP2

16

Q02086
STPSKAAKFFPYSSA

STK10

951

O94804
DSEPKSFSAPATQAY

TNS1

1041

Q9HBL0
EADKIYSFTDNAPSP

ZNF609

791

O15014
FDPQYNKDATSRPTD

SEC63

256

Q9UGP8
FYLDKSNSPPNSTSK

PREX2

1451

Q70Z35
SNSPPNSTSKAAYVD

PREX2

1456

Q70Z35
RNSFSSYAQLPKPTS

VIPAS39

91

Q9H9C1
ADPNYASEKPSTAFC

SLAMF9

221

Q96A28
PNDASTLKFEVYPTS

UGT2B11

66

O75310
VAKSSLQYSSPAPDG

GART

631

P22102
PSFTAPSFLKSFYQN

TBC1D4

706

O60343
KPSTTYQQPDSSYGA

SETD2

1266

Q9BYW2
EPSTSVSAYDQLKAP

ZNF608

611

Q9ULD9
APSKSTVYVSNLPFS

ZCRB1

6

Q8TBF4
SYSISSTLNPQAPEF

USP10

76

Q14694
FHDSKPSSSSPVAYV

USP10

346

Q14694
VNESYFKPSPTCSSI

TARBP1

581

Q13395
KPSPSSDNLYSAFTS

WNK1

2186

Q9H4A3
SVSTDPKPYIFSDAQ

ZNF831

1456

Q5JPB2
PNTDPAKYSESTSAT

ZNF275

36

Q9NSD4
YQLPSFPEPKSSTQA

SIGLEC10

641

Q96LC7
ASPDYNRTNSPSSAK

TRIP12

76

Q14669
SHFAFNSASPPKSYI

TBC1D19

331

Q8N5T2
ASNLSPDTQLYPDFT

TPRX2

246

P0DV77
SACLYSPSSQKPAAV

TTI1

101

O43156
YPESQKDTQSIDSPF

WNK3

1131

Q9BYP7
TQFSDDEYKTPLATP

VPS13D

761

Q5THJ4
NYLASKPDTPQTSGT

MYO1D

826

O94832
ARPKYFFPSTNTTAA

MYPN

721

Q86TC9