Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

1.57e-0651093GO:0030156
GeneOntologyMolecularFunctionRNA helicase activity

DDX1 SUPV3L1 DDX24 SNRNP200 AQR TDRD12

4.30e-06781096GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DDX1 SUPV3L1 DDX24 SNRNP200 AQR TDRD12

4.99e-06801096GO:0008186
GeneOntologyMolecularFunctionATP hydrolysis activity

CCT3 DNAH10 ABCA12 HSP90AA5P DDX1 IQCA1 SUPV3L1 MORC3 DDX24 SNRNP200 AQR TDRD12

5.25e-0644110912GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

CCT3 DNAH10 ABCA12 MSH4 HSP90AA5P DDX1 IQCA1 SUPV3L1 MORC3 DDX24 SNRNP200 AQR TDRD12

3.03e-0561410913GO:0140657
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

NUGGC CCT3 DNAH10 ABCA12 HSP90AA5P DDX1 IQCA1 SUPV3L1 EIF5B MORC3 DDX24 SNRNP200 AQR TDRD12

8.24e-0577510914GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

NUGGC CCT3 DNAH10 ABCA12 HSP90AA5P DDX1 IQCA1 SUPV3L1 EIF5B MORC3 DDX24 SNRNP200 AQR TDRD12

1.89e-0483910914GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

NUGGC CCT3 DNAH10 ABCA12 HSP90AA5P DDX1 IQCA1 SUPV3L1 EIF5B MORC3 DDX24 SNRNP200 AQR TDRD12

1.91e-0484010914GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

NUGGC CCT3 DNAH10 ABCA12 HSP90AA5P DDX1 IQCA1 SUPV3L1 EIF5B MORC3 DDX24 SNRNP200 AQR TDRD12

1.91e-0484010914GO:0016818
GeneOntologyMolecularFunctionhelicase activity

DDX1 SUPV3L1 DDX24 SNRNP200 AQR TDRD12

2.31e-041581096GO:0004386
GeneOntologyMolecularFunctiontransmembrane transporter binding

AKAP6 ANK2 SH3GL1 SH3GL2 KCNQ1 KCNQ3

3.64e-041721096GO:0044325
GeneOntologyMolecularFunction3'-5' RNA helicase activity

SUPV3L1 AQR

4.37e-0461092GO:0034458
GeneOntologyBiologicalProcessfertilization

CCT3 TEX11 RIMBP3 KMT2C RIMBP3C CFAP57 RIMBP3B CFAP69 TDRD12

1.09e-052631099GO:0009566
GeneOntologyBiologicalProcessDNA metabolic process

NUGGC REXO4 PDGFA CCT3 RBBP8 NOP53 MSH4 TEX11 DDX1 HNRNPU FANCA BAZ1A DBF4 SUPT6H SUPV3L1 EPC1 PHF10 MNAT1

1.39e-05108110918GO:0006259
GeneOntologyBiologicalProcessregulation of chromatin organization

HNRNPU BAZ1A EPC1 MLLT3

5.82e-05401094GO:1902275
GeneOntologyCellularComponenttranscription elongation factor complex

ICE2 CDK13 SUPT6H CCNL1 MLLT3

1.14e-05561105GO:0008023
GeneOntologyCellularComponentlamellar body membrane

ABCA12 TMEM63B

1.64e-0441102GO:0097232
MousePhenoectopic manchette

RIMBP3 RIMBP3C RIMBP3B CFAP69

6.88e-0619944MP:0009377
MousePhenodecreased papilloma incidence

NOP53 PAK1

4.47e-052942MP:0020438
DomainK_chnl_volt-dep_KCNQ_C

KCNQ4 KCNQ1 KCNQ3

1.86e-0651083IPR013821
DomainK_chnl_volt-dep_KCNQ

KCNQ4 KCNQ1 KCNQ3

1.86e-0651083IPR003937
DomainKCNQ_channel

KCNQ4 KCNQ1 KCNQ3

1.86e-0651083PF03520
Domain-

NUGGC DNAH10 ABCA12 MSH4 PAPSS1 DDX1 HNRNPU TRANK1 IQCA1 SBNO1 SUPV3L1 EIF5B DDX24 SNRNP200 AQR TDRD12

5.89e-06746108163.40.50.300
DomainP-loop_NTPase

NUGGC DNAH10 ABCA12 MSH4 PAPSS1 DDX1 HNRNPU TRANK1 IQCA1 SBNO1 SUPV3L1 EIF5B DDX24 SNRNP200 AQR TDRD12

2.87e-0584810816IPR027417
DomainDUF3398

DOCK9 DOCK10

4.89e-0461082PF11878
DomainDOCK_C/D_N

DOCK9 DOCK10

4.89e-0461082IPR021816
DomainDEAD/DEAH_box_helicase_dom

DDX1 DDX24 SNRNP200 TDRD12

8.47e-04731084IPR011545
DomainDEAD

DDX1 DDX24 SNRNP200 TDRD12

8.47e-04731084PF00270
DomainVG_K_chnl

KCNQ4 KCNQ1 KCNQ3

9.04e-04331083IPR028325
DomainSH3_9

NEB RIMBP3 RIMBP3C RIMBP3B

1.09e-03781084PF14604
DomainSH3_2

SH3GL2 RIMBP3 RIMBP3C RIMBP3B

1.56e-03861084PF07653
DomainSH3_2

SH3GL2 RIMBP3 RIMBP3C RIMBP3B

1.56e-03861084IPR011511
DomainSH3

SH3GL1 SH3GL2 NEB RIMBP3 RIMBP3C RIMBP3B

1.60e-032161086SM00326
DomainSH3

SH3GL1 SH3GL2 NEB RIMBP3 RIMBP3C RIMBP3B

1.60e-032161086PS50002
DomainSH3_domain

SH3GL1 SH3GL2 NEB RIMBP3 RIMBP3C RIMBP3B

1.76e-032201086IPR001452
DomainDHR-1_domain

DOCK9 DOCK10

1.76e-03111082IPR027007
DomainDHR_2

DOCK9 DOCK10

1.76e-03111082PS51651
DomainDHR_1

DOCK9 DOCK10

1.76e-03111082PS51650
DomainDHR-2

DOCK9 DOCK10

1.76e-03111082PF06920
DomainDOCK

DOCK9 DOCK10

1.76e-03111082IPR026791
DomainDOCK_C

DOCK9 DOCK10

1.76e-03111082IPR010703
DomainDOCK-C2

DOCK9 DOCK10

1.76e-03111082PF14429
DomainDHR-2

DOCK9 DOCK10

1.76e-03111082IPR027357
DomainBAR

SH3GL1 SH3GL2

3.31e-03151082SM00721
DomainSpectrin_alpha_SH3

SH3GL1 SH3GL2

3.31e-03151082IPR013315
DomainBAR

SH3GL1 SH3GL2

3.31e-03151082PF03114
DomainHelicase_C

DDX1 SUPV3L1 DDX24 SNRNP200

3.46e-031071084PF00271
DomainHELICc

DDX1 SUPV3L1 DDX24 SNRNP200

3.46e-031071084SM00490
DomainHelicase_C

DDX1 SUPV3L1 DDX24 SNRNP200

3.57e-031081084IPR001650
DomainHELICASE_CTER

DDX1 SUPV3L1 DDX24 SNRNP200

3.69e-031091084PS51194
DomainHELICASE_ATP_BIND_1

DDX1 SUPV3L1 DDX24 SNRNP200

3.69e-031091084PS51192
DomainBAR_dom

SH3GL1 SH3GL2

3.77e-03161082IPR004148
DomainPTPc_motif

PTPN12 PTPRB MTM1

4.83e-03591083SM00404
DomainTyr_Pase_cat

PTPN12 PTPRB MTM1

4.83e-03591083IPR003595
DomainBAR

SH3GL1 SH3GL2

5.31e-03191082PS51021
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

TPP2 CCT3 RPS4X PSME1 HSP90AA5P IKBIP DDX1 HNRNPU PPM1G EEF1D UBXN4 SUPT6H TLN1 AP3B2 SNRNP200 ATP5PD RPL7A HDGF

2.53e-108471121835235311
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

CCT3 SH3GL1 MACROD1 NDUFA2 PSME1 IKBIP HNRNPU PPM1G EEF1D PTPN12 UBXN4 SUPV3L1 TLN1 PAK1 EIF5B EXOC1 DDX24 ATP5PD RPL7A HDGF

1.40e-0813671122032687490
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

CCT3 LEMD3 RPS4X SH3GL1 PSME1 HSP90AA5P DDX1 HNRNPU PPM1G EEF1D TLN1 SNRNP200 RPL7A

2.12e-085381121328524877
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

TPP2 CCT3 RPS4X SH3GL1 PSME1 DDX1 HNRNPU PPM1G EEF1D SBNO1 CDK13 SUPT6H TLN1 EIF5B DDX24 SNRNP200 ATP5PD RPL7A AQR HDGF

2.48e-0814151122028515276
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

REXO4 CCT3 DNAH10 NOP53 RPS4X DDX1 HNRNPU EEF1D SBNO1 BAZ1A SUPT6H SUPV3L1 CDC16 TLN1 EIF5B DDX24 SNRNP200 RPL7A AQR HDGF

2.79e-0814251122030948266
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

REXO4 CCT3 NOP53 RPS4X DDX1 HNRNPU RBM27 CDK13 SUPT6H SUPV3L1 EIF5B DDX24 SNRNP200 RPL7A AQR

5.21e-088071121522681889
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

TPP2 CCT3 RBBP8 RPS4X HNRNPU EEF1D VPS13D USP4 SNRNP200

7.57e-08235112930258100
Pubmed

Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors.

KCNQ4 KCNQ1 KCNQ3

1.30e-074112310713961
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

1.30e-074112319091768
Pubmed

A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly.

KCNQ4 KCNQ1 KCNQ3

1.30e-074112312524525
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CCT3 PSME1 PAPSS1 DDX1 PPM1G EEF1D SBNO1 RBM27 BAZ1A CDK13 SUPT6H CDC16 EIF5B MNAT1 AQR HDGF

1.68e-0710141121632416067
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ANK2 PDGFA CCT3 RBBP8 RPS4X NEB DDX1 FER1L6 HNRNPU EEF1D UBXN4 SBNO1 BAZ1A CDK13 FAM161A EIF5B CFAP69 ATP5PD RPL7A

1.73e-0714421121935575683
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

REXO4 HLF HNRNPU CDK13 DDX24 MNAT1 SNRNP200 RPL7A AQR

1.73e-07259112930404004
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

TPP2 CCT3 RPS4X SH3GL1 PSME1 ZZEF1 PAPSS1 DDX1 HNRNPU PPM1G EEF1D PTPN12 SBNO1 MYCBP TLN1 EIF5B SNRNP200 RPL7A HDGF

1.98e-0714551121922863883
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TPP2 REXO4 CCT3 NOP53 RPS4X PPM1G SUPT6H TLN1 EIF5B DDX24 SNRNP200 RPL7A AQR

1.99e-076531121322586326
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

TPP2 REXO4 CCT3 RPS4X DDX1 HNRNPU RBM27 CDK13 MYCBP EIF5B DDX24 SNRNP200 RPL7A

3.04e-076781121330209976
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

3.24e-075112317855024
Pubmed

The contribution of Kv7 channels to pregnant mouse and human myometrial contractility.

KCNQ4 KCNQ1 KCNQ3

3.24e-075112320132415
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

REXO4 CCT3 NOP53 RPS4X CD109 IKBIP DDX1 HNRNPU PPM1G EEF1D RBM27 CDC16 EIF5B DDX24 SNRNP200 RPL7A AQR

5.80e-0712571121736526897
Pubmed

Novel expression and regulation of voltage-dependent potassium channels in placentas from women with preeclampsia.

KCNQ4 KCNQ1 KCNQ3

6.46e-076112321730298
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

REXO4 CCT3 NOP53 RPS4X SH3GL1 DDX1 HNRNPU PPM1G EEF1D RBM27 SUPT6H DDX24 SNRNP200 RPL7A HDGF

6.96e-079891121536424410
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

TPP2 DYM CCT3 NOP53 SH3GL1 CD109 PSME1 DDX1 HNRNPU PPM1G NBAS EEF1D TLN1 EIF5B EXOC1 DDX24 SNRNP200 ATP5PD

8.11e-0714401121830833792
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

RPS4X FAT3 NEB FER1L6 EEF1D DDX24 SNRNP200 RPL7A

9.71e-07234112836243803
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

TPP2 C10orf90 NEB PPM1G KMT2C BAZ1A CDC16 TLN1 EXOC1

1.07e-06322112926514267
Pubmed

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.

TPP2 CCT3 RPS4X SH3GL1 DDX1 HNRNPU TLN1 SNRNP200 ATP5PD RPL7A

1.07e-064181121032552912
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

LEMD3 PPM1G CCDC66 RBM27 TLN1 EPC1 EXOC1 MPHOSPH9 MORC3 MNAT1 ATP5PD HDGF

1.22e-066451121225281560
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

CCT3 RBBP8 RPS4X ICE2 SH3GL1 PSME1 HSP90AA5P DDX1 HNRNPU PPM1G EEF1D CDC16 EIF5B DDX24 PHF10 SNRNP200 RPL7A

1.32e-0613351121729229926
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

REXO4 CCT3 RPS4X DOCK10 DDX1 HNRNPU EEF1D PTPN12 BAZ1A SUPV3L1 TLN1 EIF5B EXOC1 DDX24 SNRNP200 RPL7A AQR

1.58e-0613531121729467282
Pubmed

Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.

RPS4X DDX1 HNRNPU RPL7A

1.97e-0628112438492217
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

CCT3 RPS4X MACROD1 PSME1 ZZEF1 DDX1 HNRNPU NBAS EEF1D TLN1 EIF5B SNRNP200 RPL7A

2.11e-068071121330575818
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

CCT3 NOP53 IKBIP KMT2C PTPN12 BAZ1A CDK13 SUPT6H MORC3 AQR

3.00e-064691121027634302
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ANK2 CCT3 RPS4X ICE2 HNRNPU PPM1G TLN1 EIF5B MPHOSPH9 SNRNP200 RPL7A HDGF

3.19e-067081121239231216
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TPP2 ANK2 CCT3 RPS4X SH3GL1 NDUFA2 DDX1 HNRNPU EEF1D TLN1 AP3B2 KCNQ3 USP4 EXOC1 SNRNP200 ATP5PD RPL7A

3.36e-0614311121737142655
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ANK2 RPS4X DOCK9 SH3GL1 SH3GL2 NDUFA2 HNRNPU PPM1G EEF1D UBXN4 CDC16 KCNQ3 EXOC1 ATP5PD RPL7A

3.94e-0611391121536417873
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

LEMD3 RPS4X IKBIP HNRNPU FANCA KMT2C RBM27 BAZ1A CDK13 SUPT6H CDC16 EPC1 DDX24 SNRNP200 ATP5PD RPL7A

4.07e-0612941121630804502
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

CCT3 RPS4X SH3GL1 PSME1 DDX1 HNRNPU PPM1G EEF1D RBM27 MYCBP TLN1 EIF5B SNRNP200 RPL7A HDGF

4.38e-0611491121535446349
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

CCT3 LEMD3 TMEM63B PAPSS1 IKBIP HNRNPU NBAS TTBK2 CDC16 MYCBP TLN1 MORC3 PHF10 SNRNP200 AQR

4.66e-0611551121520360068
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ERO1B ANK2 LEMD3 NDUFA2 IKBIP PPM1G NBAS UBXN4 SUPT6H TLN1 EIF5B TMEM131L DDX24 SNRNP200 ATP5PD RPL7A AQR

5.59e-0614871121733957083
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

REXO4 LEMD3 NOP53 KMT2C UBXN4 GZF1 RBM27 BAZ1A CDK13 SUPT6H CDC16 TLN1 CCNL1 EIF5B MNAT1 ATP5PD AQR

6.10e-0614971121731527615
Pubmed

The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.

RPS4X DDX1 HNRNPU SUPT6H CDC16 SNRNP200 RPL7A

7.60e-06220112734091597
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

REXO4 RPS4X HNRNPU GZF1 MYCBP AP3B2 MNAT1 SNRNP200 RPL7A

8.69e-06417112936537216
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

AKAP6 DOCK9 GNPTAB DOCK10 KMT2C TLN1 SNRNP200

8.80e-06225112712168954
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

NOP53 DDX1 HNRNPU PPM1G EEF1D SBNO1 RBM27 SUPT6H CDC16 TLN1 HDGF

8.88e-066531121133742100
Pubmed

KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness.

KCNQ4 KCNQ3

1.03e-052112210025409
Pubmed

Heterogeneity in Kv7 channel function in the cerebral and coronary circulation.

KCNQ4 KCNQ1

1.03e-052112225476662
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

1.15e-0514112317662146
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

CCT3 RPS4X SH3GL1 PAPSS1 DDX1 HNRNPU EEF1D TLN1 PAK1 EIF5B MLLT3 DDX24 RPL7A AQR HDGF

1.16e-0512471121527684187
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

CCT3 RPS4X DDX1 HNRNPU BAZ1A TLN1 MORC3 SNRNP200

1.27e-05332112832786267
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

REXO4 LEMD3 NOP53 RPS4X DDX1 HNRNPU EEF1D RBM27 BAZ1A EIF5B DDX24 SNRNP200 ATP5PD

1.28e-059541121336373674
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TPP2 CCT3 PSME1 DDX1 HNRNPU PPM1G KMT2C EEF1D RBM27 CDK13 TLN1 EIF5B SNRNP200 HDGF

1.28e-0511031121434189442
Pubmed

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

CCT3 RPS4X DDX1 HNRNPU KMT2C EEF1D BAZ1A DDX24

1.30e-05333112836779763
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

CCT3 NOP53 RPS4X DDX1 HNRNPU RBM27 RPL7A

1.53e-05245112735652658
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

ANK2 CCT3 RPS4X HNRNPU PPM1G FAM228B CDC16 MYCBP EIF5B DDX24 SNRNP200 RPL7A AQR

1.54e-059711121333306668
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

LEMD3 SH3GL1 IKBIP NBAS EEF1D VPS13D UBXN4 RBM27 TLN1 TMEM131L

1.59e-055681121037774976
Pubmed

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

NOP53 SH3GL1 ZZEF1 PPM1G RBM27 CDC16 MYCBP

1.61e-05247112732989298
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TPP2 CCT3 NOP53 CD109 PSME1 PAPSS1 IKBIP HNRNPU EEF1D PTPN12 BAZ1A EIF5B ATP5PD RPL7A AQR

1.83e-0512971121533545068
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

REXO4 NOP53 RPS4X DDX1 HNRNPU EEF1D RBM27 BAZ1A DDX24 SNRNP200 RPL7A AQR

1.92e-058471121235850772
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

CCT3 DDX1 HNRNPU SUPV3L1 CDC16 TLN1 PAK1 EXOC1 SNRNP200 AQR

1.96e-055821121020467437
Pubmed

CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1.

RPS4X DDX1 HNRNPU PPM1G RPL7A

1.96e-05101112534462429
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

CCT3 RPS4X DOCK9 HSP90AA5P DDX1 HNRNPU PPM1G EEF1D RBM27 CDK13 PHF10 SNRNP200 ATP5PD RPL7A

2.10e-0511531121429845934
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ICE2 GNPTAB MACROD1 C10orf90 PAPSS1 NBAS KMT2C SBNO1 CDK13 DBF4 CDC16 EPC1 TMEM131L CYB5R4 PHF10

2.39e-0513271121532694731
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CCT3 RPS4X DDX1 HNRNPU EEF1D BAZ1A SUPT6H TLN1 EIF5B SNRNP200 ATP5PD RPL7A AQR

2.67e-0510241121324711643
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

REXO4 CCT3 LCA5L ZZEF1 HNRNPU FANCA KMT2C TLN1 ISCU CFAP57 SNRNP200

2.68e-057361121129676528
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

REXO4 CCT3 NOP53 RPS4X RBM27 CDK13 EIF5B DDX24 RPL7A

2.77e-05483112936912080
Pubmed

Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.

RPS4X DDX1 HNRNPU SNRNP200 RPL7A

2.83e-05109112529511296
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

RPS4X IKBIP DDX1 HNRNPU EIF5B DDX24 PHF10 SNRNP200 RPL7A

2.91e-05486112930940648
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

LEMD3 RPS4X NBAS UBXN4 TLN1 TMEM131L SNRNP200 RPL7A

3.04e-05375112832788342
Pubmed

Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits.

KCNQ4 KCNQ1

3.08e-053112219687231
Pubmed

Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes.

ANK2 KCNQ1

3.08e-053112217161064
Pubmed

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.

DOCK9 DOCK10

3.08e-053112232241915
Pubmed

The contribution of genes involved in potassium-recycling in the inner ear to noise-induced hearing loss.

KCNQ4 KCNQ1

3.08e-053112216823764
Pubmed

Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis.

KCNQ4 KCNQ3

3.08e-053112218786918
Pubmed

Single point mutation in Bin/Amphiphysin/Rvs (BAR) sequence of endophilin impairs dimerization, membrane shaping, and Src homology 3 domain-mediated partnership.

SH3GL1 SH3GL2

3.08e-053112222167186
Pubmed

Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity.

KCNQ4 KCNQ1

3.08e-053112217519950
Pubmed

Tannic acid activates the Kv7.4 and Kv7.3/7.5 K(+) channels expressed in HEK293 cells and reduces tension in the rat mesenteric arteries.

KCNQ4 KCNQ3

3.08e-053112226969140
Pubmed

CDK13/CDC2L5 interacts with L-type cyclins and regulates alternative splicing.

CDK13 CCNL1

3.08e-053112217261272
Pubmed

Relationship of DDX1 and NAG gene amplification/overexpression to the prognosis of patients with MYCN-amplified neuroblastoma.

DDX1 NBAS

3.08e-053112217028906
Pubmed

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.

CCT3 RPS4X NDUFA2 DDX1 HNRNPU EEF1D TLN1 SNRNP200 RPL7A

3.15e-05491112922623428
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

TPP2 CCT3 DDX1 HNRNPU EEF1D TLN1 EIF5B SNRNP200 RPL7A

3.30e-05494112926831064
Pubmed

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.

RPS4X HNRNPU SUPT6H CCNL1 SNRNP200 RPL7A

3.43e-05188112629721183
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

TPP2 RPS4X HNRNPU EEF1D CDK13 AP3B2 PAK1 EIF5B AQR

3.51e-05498112936634849
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

REXO4 NOP53 DDX1 HNRNPU RBM27 BAZ1A CDK13 DDX24 SNRNP200 RPL7A AQR

3.54e-057591121135915203
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PTPN12 RBM27 CDK13 CDC16 MTM1 EPC1 PAK1 EIF5B DDX24

3.79e-05503112916964243
Pubmed

Mass spectrometry-based proteomics revealed Glypican-1 as a novel ADAM17 substrate.

PDGFA CCT3 HNRNPU EEF1D RPL7A

3.82e-05116112527576135
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

CCT3 RBBP8 KMT2C DBF4 CDC16

4.32e-05119112523508102
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

RPS4X HNRNPU PPM1G EEF1D GZF1 CDK13 EIF5B DDX24 SNRNP200 RPL7A

5.30e-056551121035819319
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 ZZEF1 KMT2C UBXN4 TRANK1 MAST4 RBM27 SUPT6H TMEM131L

5.59e-05529112914621295
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

CCT3 NOP53 RPS4X CD109 HSP90AA5P DDX1 HNRNPU EEF1D CDK13 EIF5B SNRNP200 RPL7A

5.76e-059491121236574265
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CCT3 DOCK10 KMT2C TLN1 AP3B2 TDRD12

6.01e-05208112633230847
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

C11orf54 MACROD1 PSME1 DDX1 EEF1D USP4 SNRNP200

6.02e-05304112732235678
Pubmed

EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia.

SH3GL1 SH3GL2

6.14e-05411229122235
Pubmed

Synaptojanin and Endophilin Mediate Neck Formation during Ultrafast Endocytosis.

SH3GL1 SH3GL2

6.14e-054112229953872
Pubmed

The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells.

RBBP8 CCDC66

6.14e-054112229855336
Pubmed

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex.

AKAP6 KCNQ1

6.14e-054112211299204
Pubmed

Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin.

SH3GL1 SH3GL2

6.14e-054112232152276
Pubmed

Expression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins.

SH3GL1 SH3GL2

6.14e-054112210816441
Pubmed

LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis.

SH3GL1 SH3GL2

6.14e-054112222998870
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

ERO1B PPM1G CDK13 DBF4 SUPT6H CDC16 EIF5B CYB5R4 DDX24 SNRNP200

6.39e-056701121022990118
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

LCA5L DOCK10 PTPN12 PTPRB CDK13 EIF5B KCNQ1 HDGF

6.74e-05420112828065597
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 ANK2 GNPTAB PSME1 SBNO1 NETO1 SUPV3L1 MTM1 PAK1 MLLT3 EXOC1 MORC3 MNAT1 SNRNP200

6.77e-0512851121435914814
InteractionH3C1 interactions

REXO4 ANK2 LEMD3 NEB ZZEF1 HNRNPU PPM1G KMT2C BAZ1A CDK13 CDC16 PAK1 MLLT3 MORC3 DDX24 RPL7A AQR HDGF

1.77e-0690111018int:H3C1
InteractionH2AB3 interactions

REXO4 PPM1G GZF1 RBM27 CDK13 DDX24 PHF10

9.74e-061361107int:H2AB3
InteractionKCNA3 interactions

ANK2 CCT3 RPS4X ICE2 DOCK10 HNRNPU PPM1G KMT2C TLN1 AP3B2 EIF5B MPHOSPH9 SNRNP200 RPL7A HDGF TDRD12

2.00e-0587111016int:KCNA3
GeneFamilyPotassium voltage-gated channels

KCNQ4 KCNQ1 KCNQ3

3.98e-0440653274
GeneFamilyX-linked mental retardation|RNA helicases

SUPV3L1 SNRNP200

6.85e-04116521168
GeneFamilyN-BAR domain containing

SH3GL1 SH3GL2

8.21e-04126521289
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

NOP53 RPS4X DOCK9 GNPTAB DOCK10 PSME1 HNRNPU KMT2C EEF1D UBXN4 TRANK1 SBNO1 RBM27 BAZ1A CDK13 CDC16 TLN1 ISCU CCNL1 EPC1 TMEM131L DDX24 SNRNP200 RPL7A

1.25e-08149211124M40023
CoexpressionGSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP

REXO4 GNPTAB HNRNPU PTPN12 GZF1 BAZ1A CDC16 MPHOSPH9 SEMA4A

7.70e-081801119M8127
CoexpressionLAKE_ADULT_KIDNEY_C9_THIN_ASCENDING_LIMB

ANK2 RBBP8 RPS4X PSME1 HNRNPU EEF1D UBXN4 RPL7A

1.92e-052681118M39228
CoexpressionGSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN

PPM1G VPS13D RBM27 DBF4 MYCBP MLLT3 MPHOSPH9

2.36e-052001117M294
CoexpressionGSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN

REXO4 IKBIP VPS13D PTPN12 UBXN4 SBNO1 CDK13

2.36e-052001117M4876
CoexpressionGSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP

LIMS2 MAST4 TMEM131L MLLT3 EXOC1 PHF10 ATP5PD

2.36e-052001117M9883
CoexpressionMURARO_PANCREAS_BETA_CELL

ERO1B RBBP8 RPS4X SH3GL2 HLF DOCK10 FAM200B KMT2C UBXN4 MAST4 SBNO1 ISCU DDX24 RPL7A

4.71e-0594611114M39169
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_B_CELL_AGEING

HNRNPU EEF1D UBXN4 BAZ1A CCNL1 EIF5B DDX24

5.89e-052311117MM3741
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_HSC_ELP_CELL

C11orf54 HLF CD109 FAM228B TRANK1 MAST4 SUPV3L1 MLLT3 MPHOSPH9

6.61e-054121119M45729
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK9 ZZEF1 NBAS PTPN12 BAZ1A CDK13 DBF4 CDC16 TMEM131L MPHOSPH9 MNAT1 AQR PLCE1

6.90e-0585611113M4500
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TEX11 HNRNPU KMT2C CDK13 CCNL1 MLLT3 DDX24 SNRNP200

3.77e-08197112857ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 ABCA12 FAT3 TEX11 NEB TRANK1 PLCE1

4.30e-0718411272cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 ABCA12 FAT3 TEX11 NEB TRANK1 PLCE1

4.30e-071841127ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 ABCA12 FAT3 TEX11 NEB TRANK1 PLCE1

4.30e-0718411272b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19|World / Disease, condition lineage and cell class

HNRNPU KMT2C CDK13 TLN1 CCNL1 EPC1 DDX24

7.54e-0720011277dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NOP53 ICE2 DOCK9 TRANK1 MAST4 TMEM131L

6.77e-0618211261aea96ee211f7b9caef7fd385233f51be6021a73
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NOP53 ICE2 DOCK9 TRANK1 MAST4 TMEM131L

6.77e-061821126b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NOP53 ICE2 DOCK9 TRANK1 MAST4 TMEM131L

6.77e-061821126c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NOP53 ICE2 DOCK9 TRANK1 MAST4 TMEM131L

6.77e-0618211264cb182ef39be2044a6ad7266f332d4177591e550
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Mild / Disease group, lineage and cell class

NOP53 ICE2 DOCK9 TRANK1 MAST4 TMEM131L

6.98e-0618311267717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

DNAH10 NOP53 ICE2 FAM228B TMEM131L AQR

7.20e-061841126ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBXN4 SBNO1 RBM27 BAZ1A CCNL1 EIF5B

8.14e-061881126d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ERO1B DOCK9 DOCK10 KMT2C CCNL1 TMEM131L

9.18e-06192112647646d7e4990be85072987f92bf18d52f8da752e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AKAP6 DNAH10 IQCA1 FAM161A CFAP57 CFAP69

9.46e-061931126ea345d34440b25f65358a53dc72831998d1c3620
ToppCellBL-critical-LOC-Epithelial-unknown_epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 FAM13C ICE2 LCA5L FAM161A CFAP69

9.74e-0619411266140ff8e776429c9593607da418b2d9c4f399d41
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

GNPTAB DOCK10 KMT2C BAZ1A TLN1 EIF5B

1.03e-0519611267bced0cc2112697593c478fa291b8ed3941fb811
ToppCell10x_3'_v3|World / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NOP53 RPS4X HNRNPU EEF1D DDX24 RPL7A

1.09e-051981126aabb8e9b162ae4cb26ea860c99decdbb51e379e1
ToppCellPBMC_fresh-frozen|World / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOP53 RPS4X HNRNPU EEF1D DDX24 RPL7A

1.09e-051981126dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GNPTAB HNRNPU CDK13 CCNL1 DDX24 SNRNP200

1.13e-051991126f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

LCA5L VPS13D UBXN4 SBNO1 BAZ1A EIF5B

1.13e-05199112661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related|6m / Sample Type, Dataset, Time_group, and Cell type.

NOP53 RPS4X NEB EEF1D BAZ1A RPL7A

1.16e-052001126ea1e3eeddbc398ac97863120f7aa3f17569ca12a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related-Oligodendrocyte/OPC|6m / Sample Type, Dataset, Time_group, and Cell type.

NOP53 RPS4X NEB EEF1D BAZ1A RPL7A

1.16e-0520011264a57f2f2dc6e2402ac4772b5cd38e033a6f1adee
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Artery|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOCK9 CD109 LIMS2 PTPRB MAST4 MLLT3

1.16e-05200112677ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte|Megakaryo-cells / Lineage, cell class and subclass

CCT3 NOP53 RPS4X PSME1 EEF1D RPL7A

1.16e-052001126f36023bb369d17b8ec8724616737738e3df01987
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DOCK9 CD109 LIMS2 PTPRB MAST4 MLLT3

1.16e-052001126b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellSevere-B_intermediate-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FAM13C NOP53 TRANK1 TMEM131L CFAP69

1.68e-05126112542a0bdbe18ef85146cac4e86b2b27d0b3b20d8a2
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 TRANK1 IQCA1 AP3B2 TDRD12

2.89e-0514111254aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 TRANK1 IQCA1 AP3B2 TDRD12

2.89e-051411125e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 TRANK1 IQCA1 AP3B2 TDRD12

2.98e-051421125759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellControl-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK2 NEB PTPN12 NETO1 TLN1

5.59e-051621125aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCellILEUM-non-inflamed-(2)_B_cell-(2)_Naive_B_cells|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NOP53 RPS4X LIMS2 EEF1D RPL7A

5.76e-0516311259add806d706f7170a49b2c2dcc14343e9befd26c
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NUGGC ABCA12 MSH4 TDRD12

7.22e-05881124fcc15c5c30517c63a835b28627c5f779d9bcd17e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NUGGC ABCA12 MSH4 TDRD12

7.22e-058811247838c65160cf81c02b923fc34f566c0610c8d81b
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC ERO1B NEB IKBIP NETO1

7.43e-05172112565b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 WDR93 IQCA1 CFAP57 CFAP69

8.28e-051761125ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 WDR93 IQCA1 FAM161A CFAP69

8.96e-051791125d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 WDR93 IQCA1 FAM161A CFAP69

8.96e-0517911258a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 ANK2 SH3GL2 RIMBP3C LIX1

8.96e-051791125b8ca29aebd25ebac441bebd769bbf98c536d3166
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

PDGFA DNAH10 LCA5L DBF4 CFAP69

9.20e-05180112585fc9b164147b28545e2397d32302eea03ef6346
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

NOP53 RPS4X WDR93 PAK1 RPL7A

9.20e-0518011256c0115d03ec58bc7ae5317bf8906617489975351
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

NOP53 ICE2 MAST4 TMEM131L ATP5PD

9.69e-051821125877b6e611626628e709568747512f2827ebb2795
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-Treg|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DOCK9 LIMS2 PTPRB MLLT3 TDRD12

9.94e-0518311255fb933acfe6bc555c90dba71e75d4be658763945
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK2 NEB PTPN12 NETO1 TLN1

9.94e-051831125278064c9f0582463b83bf156d34e77f60187613b
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytotoxic_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RPS4X NBAS EEF1D SUPV3L1 RPL7A

1.05e-041851125eeef122d64b48b950a4cf3948b64f4ffd9f3ebe0
ToppCelldroplet|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4X NDUFA2 EEF1D ATP5PD RPL7A

1.05e-0418511254c8a25f36cbf43fc78d38dfeb3f1cab160bb029d
ToppCellControl|World / Disease group, lineage and cell class

NOP53 RPS4X EEF1D ATP5PD RPL7A

1.05e-0418511257e8add6ca19067cf451a603a3506b83e7dc3b615
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

GNPTAB DOCK10 NBAS MTM1 TMEM131L

1.05e-041851125a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AKAP6 DNAH10 WDR93 CFAP57 CFAP69

1.05e-0418511255e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell(5)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

AKAP6 PDGFA DOCK10 KCNQ4 PLCE1

1.07e-041861125acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell(5)_Pericytes-(50)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

AKAP6 PDGFA DOCK10 KCNQ4 PLCE1

1.07e-04186112567b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

GNPTAB DOCK10 NBAS MTM1 TMEM131L

1.07e-0418611258571956890fc9894d766ba294a28e376b4aba428
ToppCellPBMC-Control|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NOP53 RPS4X EEF1D ATP5PD RPL7A

1.10e-04187112591464e5b7fa5cca7810b45f41b933d3a5a6e3c95
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBXN4 BAZ1A CCNL1 EIF5B DDX24

1.10e-041871125663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 IQCA1 FAM161A CFAP57 CFAP69

1.10e-04187112504dba2ed09ee4180830bdf0191921696697ea234
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LEMD3 NBAS AGFG2 KCNQ1 PHF10

1.10e-041871125c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK9 CD109 PTPRB KCNQ1 MPHOSPH9

1.10e-0418711253699d5e71d779da922920aa3160895db187bf81b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK9 CD109 PTPRB KCNQ1 MPHOSPH9

1.10e-041871125033ba52c0c2f9978784947098fa697368ae44834
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 IQCA1 FAM161A CFAP57 CFAP69

1.10e-041871125805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellPBMC-Control|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NOP53 RPS4X EEF1D ATP5PD RPL7A

1.10e-041871125b38017ffc87fb04d4e4d3755f729f9c1470bb001
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_memory_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RPS4X NBAS EEF1D SUPV3L1 RPL7A

1.13e-04188112576f9b4276455026537a62b0e6d4883ddb68f38ba
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

DNAH10 VPS13D FAM161A CFAP57 CFAP69

1.13e-041881125f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ERO1B DOCK10 KMT2C CCNL1 TMEM131L

1.13e-041881125ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAM13C DOCK9 CD109 LIMS2 PTPRB

1.13e-041881125117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

DNAH10 IQCA1 FAM161A MYCBP CFAP69

1.13e-0418811258f30535a32968a81a304315a49c0d90a77d36948
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NOP53 RPS4X DOCK9 EEF1D MLLT3

1.13e-041881125f7dd01084ad14d2a2d8adf552e811b84eebf5514
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH10 IQCA1 FAM161A CFAP57 CFAP69

1.16e-041891125057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

AKAP6 RPS4X SH3GL2 MAST4 RPL7A

1.16e-041891125b46adb47768a7b6d801c457d7ba65508edfc36a5
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH10 IQCA1 FAM161A CFAP57 CFAP69

1.16e-0418911259f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH10 IQCA1 FAM161A CFAP57 CFAP69

1.16e-041891125e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellhuman_hepatoblastoma-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DOCK9 CD109 PTPRB MAST4 KCNQ3

1.19e-0419011258d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

DOCK9 CD109 LIMS2 PTPRB MLLT3

1.19e-04190112578e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellControl|World / Disease condition and Cell class

NOP53 RPS4X EEF1D ATP5PD RPL7A

1.22e-04191112517bc87bc638fd98defdaec908300728dd76b0e8c
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH10 IQCA1 FAM161A CFAP57 CFAP69

1.22e-04191112596483adb97c81208aa513782550acd8a08b63866
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

NOP53 RPS4X DOCK9 MAST4 RPL7A

1.22e-04191112525dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCelldroplet-Tongue-Unstain-18m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 RPS4X EEF1D ATP5PD RPL7A

1.25e-04192112545ff9555f9a9fccc650885956005b2e5b4820a56
ToppCelldroplet-Tongue-Unstain|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 RPS4X EEF1D ATP5PD RPL7A

1.25e-0419211250f0fae7e1177609eff82fa4452042306297a7103
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

FANCA EEF1D CCNL1 EIF5B HDGF

1.25e-0419211259cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-suprabasal_differentiating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 RPS4X EEF1D ATP5PD RPL7A

1.25e-04192112542b821381fb995fc04589356fd81e8eeeb675757
ToppCellControl-B_intermediate-10|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK2 NEB PTPN12 NETO1 TLN1

1.25e-041921125224bd958369ba8fa0d7be2126f7dc61c9f6ac19d
ToppCelldroplet-Tongue-Unstain-18m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 RPS4X EEF1D ATP5PD RPL7A

1.25e-041921125b198e42a962c4e24ea9faad867ca1255316a5d99
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOP53 EEF1D CCDC66 DDX24 RPL7A

1.28e-0419311254e78ddc96d8e403a21c4a303b1f26512d2ac91e8
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

RPS4X EEF1D BAZ1A KCNQ3 MLLT3

1.28e-0419311252088f1d210c73f74685492c63065c62ac3f553e9
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

RPS4X EEF1D BAZ1A KCNQ3 MLLT3

1.28e-041931125f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-basal_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 NOP53 RPS4X EEF1D RPL7A

1.28e-04193112513282e849b11f48085f0840d112a06e896b32cd7
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK9 CD109 LIMS2 PTPRB AGFG2

1.28e-04193112501c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-22|World / Primary Cells by Cluster

ANK2 DNAH10 RPS4X MLLT3 RPL7A

1.28e-0419311253b927d4b8ecb21a408424ef91a23746c21741f49
ToppCellCOVID-19_Severe-B_intermediate|COVID-19_Severe / disease group, cell group and cell class

ANK2 NOP53 LIMS2 NETO1 DDX24

1.31e-0419411253418308da7f1278ae2bf3fb61fc361b222e30043
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 LCA5L WDR93 CFAP57 CFAP69

1.31e-0419411251ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-IPC_like-IPCs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

FAM13C RPS4X EEF1D MLLT3 RPL7A

1.31e-0419411252378a98452f6ec33870eeb994b8b812e9b507f4c
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-IPC_like|6_mon / Sample Type, Dataset, Time_group, and Cell type.

FAM13C RPS4X EEF1D MLLT3 RPL7A

1.31e-0419411257ba0445a486feac18b3a4fd6f2855c102e374e2d
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TPP2 FAM161A DBF4 PHF10 PLCE1

1.31e-041941125dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellCV-Moderate-0|CV / Virus stimulation, Condition and Cluster

NOP53 RPS4X EEF1D ISCU RPL7A

1.31e-0419411259ff69139dae007fcc349daefcb5021defb0e0d2a
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 LCA5L IQCA1 CFAP57 CFAP69

1.34e-041951125e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 LCA5L IQCA1 CFAP57 CFAP69

1.34e-04195112507a6bcef6af93ed87df455dee624037cb75e011a
ToppCellnormal_Pleural_Fluid|World / Location, Cell class and cell subclass

NOP53 RPS4X PSME1 EEF1D RPL7A

1.37e-0419611257029c9f4a826f6cfdcb5f7a472fba94e8945a771
ToppCellHealthy-CD4+_T_naive|Healthy / disease group, cell group and cell class

NOP53 RPS4X EEF1D MLLT3 RPL7A

1.37e-041961125dd77ce987dfcff196e489f8007ffefe5405afffb
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_Naive_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CCT3 NOP53 RPS4X EEF1D RPL7A

1.37e-041961125eda187f50e1bcf8f9bc9af3ea05c63748d66570a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 RBBP8 FAT3 MAST4 KCNQ1

1.37e-041961125c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 LCA5L IQCA1 CFAP57 CFAP69

1.37e-04196112527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellMegakaryocytic-erythropoietic-MEP-MEP|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

NOP53 RPS4X PSME1 MLLT3 RPL7A

1.37e-0419611254e97010185fa9392da8f69e7b2a7395bf063f8ff
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

NEB HNRNPU KMT2C UBXN4 EIF5B DDX24

5.29e-0749676GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
ComputationalNeighborhood of RAP1A

TPP2 RBBP8 CDK13 MYCBP EIF5B PHF10

2.28e-04140676MORF_RAP1A
DrugN-(1-(3-morpholin-4-ylphenyl)ethyl)-3-phenylacrylamide

KCNQ4 KCNQ1 KCNQ3

2.17e-0661103ctd:C476437
Drugisovaleramide

KCNQ4 KCNQ1 KCNQ3

6.04e-0681103CID000010930
Drugvalrocemide

KCNQ4 KCNQ1 KCNQ3

6.04e-0681103CID006918293
Drugeslicarbazepine acetate

KCNQ4 KCNQ1 KCNQ3

6.04e-0681103CID000179344
Drugvalnoctamide

KCNQ4 CCNL1 KCNQ1 KCNQ3

1.47e-05311104CID000020140
Diseaselong QT syndrome (implicated_via_orthology)

KCNQ4 KCNQ1 KCNQ3

5.31e-06101063DOID:2843 (implicated_via_orthology)
Diseaselong QT syndrome (is_implicated_in)

ANK2 KCNQ1

2.65e-0471062DOID:2843 (is_implicated_in)
Diseaselysosomal protective protein measurement

GNPTAB TMEM131L

2.65e-0471062EFO_0008215
Diseaseprimary ovarian insufficiency (is_implicated_in)

MSH4 FANCA

3.53e-0481062DOID:5426 (is_implicated_in)
DiseaseNeurodevelopmental Disorders

ANK2 HNRNPU KMT2C PAK1

3.59e-04931064C1535926
DiseaseSquamous cell carcinoma of esophagus

FAT3 PSME1 KMT2C PLCE1

3.90e-04951064C0279626
Diseaseplatelet component distribution width

DOCK9 HLF DOCK10 TEX11 ZZEF1 TRANK1 TLN1 EPC1 TMEM131L MLLT3

3.97e-0475510610EFO_0007984
DiseaseNephroblastoma

DDX1 NBAS

5.65e-04101062Orphanet_654
Diseaselymphocyte count

DNAH10 RBBP8 MACROD1 DOCK10 LIMS2 PTPN12 CCDC66 SBNO1 CDK13 SUPV3L1 TLN1 USP4 MORC3 PLCE1

7.58e-04146410614EFO_0004587
Diseasecreatinine measurement

ICE2 TEX11 NEB DDX1 PPM1G PTPN12 AP3B2 KCNQ1 TMEM131L CFAP57 TDRD12

9.12e-0499510611EFO_0004518
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

KCNQ4 KCNQ3

9.72e-04131062DOID:0112202 (implicated_via_orthology)
Diseaseatrial fibrillation (is_implicated_in)

ANK2 KCNQ1

1.13e-03141062DOID:0060224 (is_implicated_in)
DiseaseRomano-Ward Syndrome

ANK2 KCNQ1

1.48e-03161062C0035828
Diseasebody mass index, high density lipoprotein cholesterol measurement

DNAH10 MACROD1

2.10e-03191062EFO_0004340, EFO_0004612
Diseasetriglyceride measurement, body mass index

DNAH10 MACROD1

2.10e-03191062EFO_0004340, EFO_0004530
Diseaseplatelet crit

DOCK10 MAST4 SBNO1 RBM27 CDK13 TLN1 KCNQ1 TMEM131L MPHOSPH9 PLCE1

2.28e-0395210610EFO_0007985
DiseaseRetinitis pigmentosa

FAM161A SEMA4A SNRNP200

2.43e-03741063cv:C0035334
DiseaseNoise-induced hearing loss

KCNQ4 KCNQ1

2.82e-03221062C0018781
DiseaseS-7-hydroxywarfarin to S-warfarin ratio measurement

LEMD3 IQCA1 AQR

3.14e-03811063EFO_0803334

Protein segments in the cluster

PeptideGeneStartEntry
DKPLEYFQRKKKDIK

FAM200B

116

P0CF97
PLKKAQYDKDNEKRT

FAM228B

156

P0C875
QDKADLIRPKRKYEK

EPC1

326

Q9H2F5
DKQDKVKQKAFVEPY

RBBP8

766

Q99708
YKVFFPRKDQKPVEK

ABCA12

651

Q86UK0
EVYFKNKEEPRKVRF

MLLT3

86

P42568
KIFPKIKKLQERDYF

ERO1B

56

Q86YB8
LAGRKVFVEIPKKKY

GZF1

226

Q9H116
LNEAFPETKLDKKKY

ATP5PD

136

O75947
KKKSPFDIKVIEDIY

AQR

36

O60306
RKKPNYELLEKEVEK

CCNL1

291

Q9UK58
FDFVEYEKDTPKKKR

DBF4

336

Q9UBU7
KPKKQYRRKLREEFV

CDK13

951

Q14004
KYFLKEKLEVIKGRE

IQCA1

121

Q86XH1
EERLRQYAEKKAKKP

EEF1D

176

P29692
VLKYLPKKDRENVKE

ASTE1

276

Q2TB18
KKDAIDPLLFKYKVQ

BAZ1A

181

Q9NRL2
NREKRKEKEKPFYSD

AP3B2

666

Q13367
YVVALVKKDKPEKEL

RBM27

31

Q9P2N5
KQPRKKYVQRKSDFD

NETO1

366

Q8TDF5
CPYQADEKVKRLKVK

RIMBP3B

406

A6NNM3
CPYQADEKVKRLKVK

RIMBP3C

406

A6NJZ7
IKAALADYKLKQEPK

ISCU

146

Q9H1K1
RPVYLKKLKKLREEE

LEMD3

36

Q9Y2U8
LEQEAKQKRDYKKEP

ANK2

2601

Q01484
KFEDLTPGKKYKIQI

PTPRB

1051

P23467
KKKFQQARKPYDVRD

KCNQ1

526

P51787
DVKDLFKENYKPLLK

nan

776

O00370
FKENYKPLLKEIKED

nan

781

O00370
KGLQEFPKDILKIKY

LRRD1

151

A4D1F6
IEPRERAKFKRKYKV

NOP53

451

Q9NZM5
KRYRKRKNKLEETFP

KMT2C

1346

Q8NEZ4
KRCYEKFPLELKKRL

LIMS2

306

Q7Z4I7
KKVLKIYNKREEDFP

MNAT1

76

P51948
FEDIPKEKRFPKFKR

GNPTAB

666

Q3T906
LDYKIKELKKQIEPR

CFAP57

976

Q96MR6
KKKFKETLRPYDVKD

KCNQ3

531

O43525
KRKFKETLRPYDVKD

KCNQ4

546

P56696
IKQFKKYIDNPKLRE

DDX1

306

Q92499
KEKYIDQELNKTKPI

HSP90AA5P

106

Q58FG0
YKKTNKEKFRIRQPE

MORC3

466

Q14149
VCPKDEDYKQRTQKK

HNRNPU

606

Q00839
YEESKEKFGKPNKRK

HDGF

66

P51858
PSLKDIYYKKQRENK

MPHOSPH9

256

Q99550
EENKKLKAKLAQYEP

MYCBP

81

Q99417
NRNYLKQPVVKEKEK

LCA5L

81

O95447
IKKARKVFIPDDLKD

HLF

211

Q16534
EKRKKIKDKESFYPL

NBAS

376

A2RRP1
KPKVYNLKKDFSRLE

IKBIP

281

Q70UQ0
RKAGQELRFYKEKKE

LIX1

236

Q8N485
EEKKKKDRFYRSILP

PAK1

46

Q13153
VPEYIKKAAKKAAEF

PHF10

196

Q8WUB8
EIVPFRVAAYNKKKK

PAPSS1

556

O43252
EEPINKRLFEKYLKD

CDC16

96

Q13042
DKALYKPKQEVKFRI

CD109

136

Q6YHK3
KRVYKKFDPVGEILK

ICE2

636

Q659A1
AKKYPDNQVKLLKEI

DOCK10

2086

Q96BY6
KRYPDNKVKLLKEVF

DOCK9

2006

Q9BZ29
KDRLKKFPELKFKYV

DYM

616

Q7RTS9
KREKYNPERAQKLKE

FANCA

31

O15360
DYKREKEKVNEKPLG

TMEM63B

346

Q5T3F8
EKVYQIKLPERDRKK

FAT3

1256

Q8TDW7
SEKYPKQLQKQREEK

CCDC66

716

A2RUB6
APRKGDKIYQEFKKL

CNPY1

21

Q3B7I2
AVKVEEPRYKKDKQL

MACROD1

136

Q9BQ69
EPRYKKDKQLNEKIS

MACROD1

141

Q9BQ69
LFKLEEREKKVYPKA

MAST4

1566

O15021
KIYKTLKKDEDIPLF

DDX24

701

Q9GZR7
KQELRKVIKEYPGKE

EXOC1

806

Q9NV70
KQEEDPEYKKKFRAN

FAM161A

271

Q3B820
LFTYVKKPEKQKIID

CFAP69

396

A5D8W1
PEEAKKFDNIDKVFK

DNAH10

1501

Q8IVF4
NKPTDKKERKYILFD

DNAH10

2176

Q8IVF4
VKEVNPKKKLFLVYR

SBNO1

1221

A3KN83
LYDIILKNFEKLKKP

PSME1

226

Q06323
FIEKRYVELKKANPD

NDUFA2

36

O43678
GKTEIKDRDKYIPKQ

FER1L6

1386

Q2WGJ9
FLDHPKKKIRDTQKY

REXO4

336

Q9GZR2
KNYEELLRAKPKRKI

NUGGC

211

Q68CJ6
FVEQEDPYRKKKLQE

TMEM131L

1186

A2VDJ0
DPYRKKKLQEKREGN

TMEM131L

1191

A2VDJ0
QFEYNEEIPKRIKKA

PLCE1

1616

Q9P212
KYRPETKQEKKQRLL

RPL7A

101

P62424
CPYQADEKVKRLKVK

RIMBP3

406

Q9UFD9
KPLRLTEKKEYDEKN

TDRD12

356

Q587J7
YEDKKRKKIPQQLES

EIF5B

446

O60841
PDIIKDQKAYKEGKL

PPM1G

76

O15355
EENVKKNRYKDILPF

PTPN12

56

Q05209
IERVFKGKYKELNKE

SEMA4A

346

Q9H3S1
KEIDIKKYARVEKIP

CCT3

191

P49368
LKKKYKEDFPRTEQV

MSH4

916

O15457
PEEAKYKLCKVRKIF

RPS4X

116

P62701
RPLDKNEVKKVLDKF

SUPV3L1

86

Q8IYB8
RKFEEKFEQEKKYRP

FAM13C

301

Q8NE31
IKPAVLKDYREEEKK

CYB5R4

131

Q7L1T6
RENKKTIFKVNKDPY

AKAP6

1876

Q13023
RDPQKVKEFLQEKYE

AGFG2

126

O95081
YDNLPEVKKKKEEQR

C10orf90

656

Q96M02
KVYDLNKIAKEIKLP

C11orf54

76

Q9H0W9
SFKYLKNKPVKELRD

SUPT6H

636

Q7KZ85
LDFDYKKKRQGKIPD

SH3GL1

166

Q99961
RVKKKPYLELKDANG

USP4

411

Q13107
KEKFKNPFYTKEINR

MTM1

506

Q13496
EYVRKKPKLKEVQVR

PDGFA

156

P04085
LDFDYKKKRQGKIPD

SH3GL2

166

Q99962
LPKEYVKQKGERKIF

TLN1

266

Q9Y490
EKLLQKKAYQPDLVK

TTBK2

966

Q6IQ55
KKAYQPDLVKLLVEK

TTBK2

971

Q6IQ55
YPKALKERIQKERKE

TPP2

121

P29144
LKKALLLYKKEEPID

TEX11

796

Q8IYF3
KKIEKKNFPFERLYD

SNRNP200

1141

O75643
KIIDRKKAPADFLEK

TSSK1B

41

Q9BXA7
LQKSYRKLEKNPEKE

WDR93

651

Q6P2C0
KEKYPVLKDVMDFIK

ZZEF1

1551

O43149
KKVSPKEKQLEYLEL

TRANK1

1746

O15050
FPRREFTKEDYKKKL

UBXN4

366

Q92575
SRKKQKEVQDKDYPL

VPS13D

1746

Q5THJ4
LSEKKYRQHPEKLKF

NEB

1711

P20929