Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionCCR4-NOT complex binding

MARF1 GARRE1

6.28e-053922GO:1905762
GeneOntologyMolecularFunctionmicrotubule binding

NUSAP1 KIF21B ALMS1 NUMA1 CCSER2 TOGARAM1 KIF4B FHDC1

8.86e-05308928GO:0008017
GeneOntologyMolecularFunctiontubulin binding

NUSAP1 KIF21B ALMS1 NUMA1 CCSER2 RAB11FIP5 TOGARAM1 KIF4B FHDC1

1.59e-04428929GO:0015631
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF21B MYH8 MYH11 MYO10 KIF4B

2.16e-04118925GO:0003774
GeneOntologyMolecularFunctionATP-dependent activity

DDX47 KIF21B MYH8 MYH11 ATP7A MYO10 ABCB5 KIF4B RUVBL2 ABCA10

5.26e-046149210GO:0140657
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

PLEKHG1 RCBTB2 RABGEF1 HERC2 TIAM2 RGL4

6.99e-04231926GO:0005085
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH8 MYH11 MYO10

7.10e-0438923GO:0000146
GeneOntologyMolecularFunctionretromer complex binding

WASHC2C WASHC2A

9.22e-0410922GO:1905394
GeneOntologyCellularComponentearly endosome membrane

ATP7A WASHC2C RAB11FIP5 RABGEF1 WASHC2A SNX19 VAMP3

4.22e-05212927GO:0031901
GeneOntologyCellularComponenteuchromatin

H1-2 H1-3 H1-4 RUVBL2

2.88e-0472924GO:0000791
DomainHistone_H5

H1-2 H1-3 H1-4

6.57e-068933IPR005819
DomainFAM21

WASHC2C WASHC2A

2.45e-052932IPR027308
DomainH15

H1-2 H1-3 H1-4

3.30e-0513933SM00526
DomainLinker_histone

H1-2 H1-3 H1-4

3.30e-0513933PF00538
DomainH15

H1-2 H1-3 H1-4

3.30e-0513933PS51504
DomainHistone_H1/H5_H15

H1-2 H1-3 H1-4

4.18e-0514933IPR005818
DomainFAM21/CAPZIP

WASHC2C WASHC2A

7.33e-053932IPR029341
DomainCAP-ZIP_m

WASHC2C WASHC2A

7.33e-053932PF15255
DomainRCC1

NEK8 RCBTB2 HERC2

1.28e-0420933PF00415
DomainRCC1_1

NEK8 RCBTB2 HERC2

1.49e-0421933PS00625
DomainRCC1_2

NEK8 RCBTB2 HERC2

1.49e-0421933PS00626
DomainRCC1_3

NEK8 RCBTB2 HERC2

1.49e-0421933PS50012
DomainReg_chr_condens

NEK8 RCBTB2 HERC2

1.72e-0422933IPR000408
Domain-

NEK8 RCBTB2 HERC2

1.72e-04229332.130.10.30
DomainRCC1/BLIP-II

NEK8 RCBTB2 HERC2

1.97e-0423933IPR009091
DomainMyosin_head_motor_dom

MYH8 MYH11 MYO10

8.89e-0438933IPR001609
DomainMYOSIN_MOTOR

MYH8 MYH11 MYO10

8.89e-0438933PS51456
DomainMyosin_head

MYH8 MYH11 MYO10

8.89e-0438933PF00063
DomainMYSc

MYH8 MYH11 MYO10

8.89e-0438933SM00242
DomainP-loop_NTPase

DDX47 KIF21B MYH8 MYH11 MYO10 ABCB5 GNL2 KIF4B RASL12 PFKFB3 RUVBL2 ABCA10

1.01e-038489312IPR027417
DomainMyosin_N

MYH8 MYH11

2.47e-0315932PF02736
DomainMyosin_N

MYH8 MYH11

2.47e-0315932IPR004009
DomainMyosin_tail_1

MYH8 MYH11

3.56e-0318932PF01576
DomainMyosin_tail

MYH8 MYH11

3.56e-0318932IPR002928
DomainMyosin-like_IQ_dom

MYH8 MYH11

3.97e-0319932IPR027401
Domain-

MYH8 MYH11

3.97e-03199324.10.270.10
DomainFA58C

CNTNAP3B CNTNAP3

4.84e-0321932SM00231
DomainFA58C_3

CNTNAP3B CNTNAP3

4.84e-0321932PS50022
DomainFA58C_1

CNTNAP3B CNTNAP3

4.84e-0321932PS01285
DomainFA58C_2

CNTNAP3B CNTNAP3

4.84e-0321932PS01286
DomainIQ

MYH8 MYH11 MYO10

5.35e-0371933PF00612
DomainF5_F8_type_C

CNTNAP3B CNTNAP3

6.30e-0324932PF00754
DomainFA58C

CNTNAP3B CNTNAP3

6.30e-0324932IPR000421
PathwayREACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF

UBN1 H1-2 H1-3 H1-4

9.36e-0717654M27189
PathwayREACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION

H1-2 H1-3 H1-4

2.59e-0513653M1018
PathwayREACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF

UBN1 H1-2 H1-4

4.09e-0515653MM14902
Pubmed

Quantitative Mass Spectrometry Reveals that Intact Histone H1 Phosphorylations are Variant Specific and Exhibit Single Molecule Hierarchical Dependence.

H1-2 H1-3 H1-4

1.85e-08393326209608
Pubmed

High-resolution mapping of h1 linker histone variants in embryonic stem cells.

H1-2 H1-3 H1-4

1.85e-08393323633960
Pubmed

The rhox homeobox gene cluster is imprinted and selectively targeted for regulation by histone h1 and DNA methylation.

H1-2 H1-3 H1-4

1.85e-08393321245380
Pubmed

H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo.

H1-2 H1-3 H1-4

7.39e-08493312808097
Pubmed

Distribution of somatic H1 subtypes is non-random on active vs. inactive chromatin II: distribution in human adult fibroblasts.

H1-2 H1-3 H1-4

7.39e-08493311746507
Pubmed

The distribution of somatic H1 subtypes is non-random on active vs. inactive chromatin: distribution in human fetal fibroblasts.

H1-2 H1-3 H1-4

7.39e-08493310997781
Pubmed

Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype.

H1-2 H1-3 H1-4

7.39e-08493311689686
Pubmed

The mouse histone H1 genes: gene organization and differential regulation.

H1-2 H1-3 H1-4

1.84e-0759339300059
Pubmed

A compendium of the histone H1 family of somatic subtypes: an elusive cast of characters and their characteristics.

H1-2 H1-3 H1-4

1.84e-07593311467742
Pubmed

A proposal for a coherent mammalian histone H1 nomenclature correlated with amino acid sequences.

H1-2 H1-3 H1-4

1.84e-0759338003976
Pubmed

Characterization of the histone H1-binding protein, NASP, as a cell cycle-regulated somatic protein.

H1-2 H1-3 H1-4

1.84e-07593310893414
Pubmed

Expression of murine H1 histone genes during postnatal development.

H1-2 H1-3 H1-4

1.84e-0759339655912
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

GARIN5B C9orf43 MYH8 MYH11 TBC1D31 ABCB5 NUMA1 H1-2 H1-3 H1-4 MARF1 ERC2 RPS19 PRX FER1L6 RYR2 VAMP3

2.51e-071442931735575683
Pubmed

Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry.

H1-2 H1-3 H1-4

3.68e-07693315595731
Pubmed

The preferential binding of histone H1 to DNA scaffold-associated regions is determined by its C-terminal domain.

H1-2 H1-3 H1-4

3.68e-07693315562002
Pubmed

The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone.

H1-2 H1-3 H1-4

3.68e-07693321425800
Pubmed

Hormone-mediated dephosphorylation of specific histone H1 isoforms.

H1-2 H1-3 H1-4

3.68e-07693311479299
Pubmed

Linker histone transitions during mammalian oogenesis and embryogenesis.

H1-2 H1-3 H1-4

3.68e-0769339499577
Pubmed

Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway.

H1-2 H1-3 H1-4

3.68e-07693322083958
Pubmed

H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain.

H1-2 H1-3 H1-4

3.68e-07693315911621
Pubmed

Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.

H1-2 H1-3 H1-4

6.43e-07793324435047
Pubmed

All known human H1 histone genes except the H1(0) gene are clustered on chromosome 6.

H1-2 H1-3 H1-4

6.43e-0779338325638
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

DDX47 MED24 H1-2 STON2 H1-3 H1-4 GNL2 PFKFB3 GARRE1 VASP

1.01e-06503931036217030
Pubmed

Histone h1 depletion impairs embryonic stem cell differentiation.

H1-2 H1-3 H1-4

1.03e-06893322589736
Pubmed

The periphilin 1-like BFAR isoform 3 is highly expressed in transcriptionally silent oocytes and involved in RNA metabolism.

MYO10 H1-2 H1-4 RPS19

1.08e-062993434175335
Pubmed

Human transcription factor protein interaction networks.

NUSAP1 PHF2 MED24 PBRM1 UBN1 ALMS1 INO80C NUMA1 MARF1 GNL2 RPS19 HERC2 WASHC2A RUVBL2 GARRE1 RAI2

1.17e-061429931635140242
Pubmed

Dynamic changes in H1 subtype composition during epigenetic reprogramming.

H1-2 H1-3 H1-4

2.19e-061093328794128
Pubmed

High-throughput kinase assays with protein substrates using fluorescent polymer superquenching.

H1-2 H1-3 H1-4

2.19e-061093315927069
Pubmed

Role of H1 linker histones in mammalian development and stem cell differentiation.

H1-2 H1-3 H1-4

3.01e-061193326689747
Pubmed

A unified phylogeny-based nomenclature for histone variants.

H1-2 H1-3 H1-4

4.00e-061293322650316
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

WASHC2C UBN1 ALMS1 RAB11FIP5 ERC2 RPS19 WASHC2A RUVBL2 GARRE1 FAM83B

4.06e-06588931038580884
Pubmed

Characterization of the mouse histone gene cluster on chromosome 13: 45 histone genes in three patches spread over 1Mb.

H1-2 H1-3 H1-4

5.19e-06139338858344
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NUSAP1 MED24 DPAGT1 TBC1D31 WASHC2C ARHGAP26 CCSER2 PHTF2 GEMIN5 WASHC2A NFAT5 TUB TIAM2

6.30e-061084931311544199
Pubmed

Dynamics and dispensability of variant-specific histone H1 Lys-26/Ser-27 and Thr-165 post-translational modifications.

H1-2 H1-4

7.07e-06293224873882
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3B CNTNAP3

7.07e-06293231150793
Pubmed

Nuclear factor of activated T cells 5 deficiency increases the severity of neuronal cell death in ischemic injury.

NFAT5 SLC5A3

7.07e-06293223172129
Pubmed

Identification of a novel Rev-interacting cellular protein.

WASHC2C WASHC2A

7.07e-06293215847701
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3B CNTNAP3

7.07e-06293226807827
Pubmed

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

WASHC2C WASHC2A

7.07e-06293220827171
Pubmed

FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.

WASHC2C WASHC2A

7.07e-06293236717248
Pubmed

Myosin X transports Mena/VASP to the tip of filopodia.

MYO10 VASP

7.07e-06293215158464
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

DDX47 PHF2 PBRM1 ARHGAP26 MARF1 PFKFB3 RUVBL2

8.85e-0627293731010829
Pubmed

CRL4DCAF8 dependent opposing stability control over the chromatin remodeler LSH orchestrates epigenetic dynamics in ferroptosis.

H1-2 H1-3 H1-4

1.01e-051693333288900
Pubmed

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.

ATP7A WASHC2C WASHC2A

1.74e-051993325355947
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PLEKHG1 TBC1D31 WASHC2C ALMS1 CARMIL1 H1-2 HERC2 WASHC2A RUVBL2 GARRE1 FAM83B

1.77e-05853931128718761
Pubmed

Human spleen histone H1. Isolation and amino acid sequences of three minor variants, H1a, H1c, and H1d.

H1-2 H1-3

2.12e-0539322613692
Pubmed

The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion.

H1-2 H1-3

2.12e-05393224525734
Pubmed

Nepsilon-formylation of lysine is a widespread post-translational modification of nuclear proteins occurring at residues involved in regulation of chromatin function.

H1-2 H1-3

2.12e-05393218056081
Pubmed

NFAT5 promotes oral squamous cell carcinoma progression in a hyperosmotic environment.

DPAGT1 NFAT5

2.12e-05393232901097
Pubmed

Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.

CFAP20DC WASHC2C WASHC2A

3.15e-052393331748650
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

DDX47 NUSAP1 PBRM1 NUMA1 H1-4 GNL2 ERC2 RPS19 HERC2 RUVBL2

3.66e-05759931035915203
Pubmed

Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis.

MYO10 VASP

4.23e-05493229993000
Pubmed

Chromatin condensing functions of the linker histone C-terminal domain are mediated by specific amino acid composition and intrinsic protein disorder.

H1-2 H1-3

4.23e-05493219072710
Pubmed

LINC01194 recruits NUMA1 to promote ubiquitination of RYR2 to enhance malignant progression in triple-negative breast cancer.

NUMA1 RYR2

4.23e-05493235750275
Pubmed

Isolation of two murine H1 histone genes and chromosomal mapping of the H1 gene complement.

H1-2 H1-3

4.23e-0549328589518
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DDX47 PHF2 SOWAHA PBRM1 ALMS1 INO80C H1-2 H1-4 GNL2 RAB11FIP5 RUVBL2 GARRE1

4.28e-051116931231753913
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

PHF2 KIF21B MYH11 SETBP1 H1-2 H1-3 H1-4 RAB11FIP5 ERC2

4.42e-0562193922794259
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

DDX47 NUSAP1 MYH11 MYO10 NUMA1 H1-2 H1-3 H1-4 GNL2 RAB11FIP5 RPS19

4.68e-05949931136574265
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

DDX47 NUMA1 H1-2 H1-4 KIF4B RPS19 HERC2 NFAT5 RUVBL2

4.70e-0562693933644029
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

PBRM1 NUMA1 H1-2 GEMIN5 KYAT3 RUVBL2

5.13e-0524493629884807
Pubmed

ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase.

H1-2 RPS19 RUVBL2

5.78e-052893326381412
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

FANCE NUSAP1 PBRM1 WASHC2C CARMIL1 NUMA1 CCSER2 KIF4B HERC2 WASHC2A RUVBL2 FAM83B

5.95e-051155931220360068
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

DDX47 KIF21B NUMA1 H1-2 H1-3 H1-4 PFKFB3 RUVBL2 VASP

7.05e-0566093932780723
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

DDX47 NUSAP1 PHF2 MYH11 PBRM1 INO80C NUMA1 STON2 MARF1 GNL2 HERC2 TRUB1 RUVBL2

7.26e-051371931336244648
Pubmed

14-3-3sigma controls mitotic translation to facilitate cytokinesis.

MYH11 H1-2 H1-3 RPS19

8.60e-058693417361185
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF21B ARHGAP26 SETBP1 CCSER2 RAB11FIP5 GARRE1 KIAA1614 TIAM2

8.92e-0552993814621295
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

KIF21B MYH11 PBRM1 NUMA1 H1-2 H1-3 H1-4 GEMIN5 RPS19 RUVBL2

9.09e-05847931035235311
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

PHF2 MED24 PBRM1 INO80C NUMA1 H1-3 HERC2 RUVBL2

9.40e-0553393830554943
Pubmed

Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis.

MYH11 H1-2 H1-3 VASP

9.41e-058893420618440
Pubmed

Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer.

MED24 H1-2 H1-3 H1-4

9.41e-058893426318153
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

WASHC2C MYO10 CARMIL1 NUMA1 KIF4B RPS19 FRMPD3 TRUB1

1.00e-0453893828524877
Pubmed

In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.

CNTNAP3B CNTNAP3

1.05e-04693234143959
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PLEKHG1 WASHC2C MYO10 ERC2 WASHC2A NFAT5 SNX19

1.14e-0440793712693553
Pubmed

Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling.

NUMA1 H1-2 H1-4

1.35e-043793336835656
Pubmed

Nucleolar proteome dynamics.

DDX47 H1-2 H1-3 H1-4 GNL2 RPS19 RUVBL2

1.36e-0441993715635413
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

WASHC2C SQLE PRMT7 WASHC2A

1.73e-0410393429539633
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ALMS1 ERC2 HERC2 GARRE1

1.80e-041049349205841
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

DDX47 PBRM1 NUMA1 CCSER2 GNL2 GEMIN5 HERC2

1.84e-0444093734244565
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

DDX47 NUMA1 H1-2 H1-3 H1-4 GNL2 RPS19

1.86e-0444193731239290
Pubmed

A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling.

MYH11 MARF1

1.96e-04893227378146
Pubmed

A FAM21-containing WASH complex regulates retromer-dependent sorting.

WASHC2C WASHC2A

1.96e-04893219922874
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

PLEKHG1 ALMS1 CCSER2 RABGEF1 RUVBL2 GARRE1 FAM83B

2.00e-0444693724255178
Pubmed

Reduction of Hox gene expression by histone H1 depletion.

H1-2 H1-3 H1-4

2.11e-044393322701719
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

DDX47 PBRM1 NUMA1 H1-2 KIF4B

2.21e-0420393522083510
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

NUSAP1 PHF2 PBRM1 UBN1 NUMA1 GNL2 HERC2 TRUB1

2.31e-0460893836089195
Pubmed

Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1.

H1-2 H1-3 H1-4

2.42e-044593333596420
Pubmed

Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.

H1-2 H1-3

2.52e-04993224412544
Pubmed

Developmentally regulated linker histone H1c promotes heterochromatin condensation and mediates structural integrity of rod photoreceptors in mouse retina.

H1-2 H1-4

2.52e-04993223645681
Pubmed

CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.

KIF21B H1-2 STON2 H1-3 H1-4 RPS19 RUVBL2

2.67e-0446893736042349
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

PBRM1 WASHC2C A2ML1 HERC2 WASHC2A NFAT5 TUB

2.92e-0447593731040226
Pubmed

A functional reference map of the RNF8 interactome in cancer.

DDX47 PBRM1 A2ML1 H1-2 RUVBL2

3.07e-0421893535831895
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

PBRM1 H1-2 RAB11FIP5 RPS19 HERC2 RUVBL2 ADGRG4 VASP

3.22e-0463993823443559
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

DDX47 NUSAP1 PBRM1 H1-2 H1-4 GNL2 RPS19

3.23e-0448393736912080
Pubmed

Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL.

H1-2 H1-3 H1-4 RUVBL2

3.41e-0412393435583604
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PHF2 ALMS1 SETBP1 ERC2 TOGARAM1

3.55e-0422593512168954
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

DDX47 UBN1 NUMA1 H1-2 H1-4 GNL2

3.58e-0434993625665578
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PHF2 MYH11 ALMS1 TOGARAM1 FHDC1 PRMT7 PRX

3.66e-0449393715368895
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PBRM1 NUMA1 H1-3 H1-4 GNL2 GEMIN5 RPS19 HERC2

3.71e-0465393822586326
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

SETBP1 MARF1 TOGARAM1

3.72e-04529339455477
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

H1-2 H1-3 H1-4 GNL2 GEMIN5 RPS19 RUVBL2 FAM83B

3.79e-0465593835819319
InteractionBSN interactions

H1-2 H1-4 ERC2 RPS19

1.83e-0535914int:BSN
InteractionCEP135 interactions

PLEKHG1 TBC1D31 WASHC2C ALMS1 CCSER2 TOGARAM1 HERC2 FAM83B

3.21e-05272918int:CEP135
InteractionH2AC18 interactions

NUMA1 H1-2 H1-3 H1-4 GEMIN5 RUVBL2

5.65e-05148916int:H2AC18
InteractionTBX1 interactions

H1-2 H1-3 H1-4

5.79e-0517913int:TBX1
InteractionCEP128 interactions

DDX47 PLEKHG1 TBC1D31 WASHC2C ALMS1 CCSER2 WASHC2A FAM83B

5.97e-05297918int:CEP128
InteractionSFN interactions

MYH11 ALMS1 NEK8 CARMIL1 H1-2 CCSER2 H1-3 RABGEF1 RPS19 RUVBL2 GARRE1 FAM83B

6.44e-056929112int:SFN
InteractionBFAR interactions

MYO10 H1-2 H1-4 RPS19

6.50e-0548914int:BFAR
Cytoband8q24.1

SQLE FER1L6

8.47e-0579328q24.1
Cytoband2p13

ALMS1 RAB11FIP5

9.99e-04239322p13
Cytoband16p13.11

MYH11 MARF1

9.99e-042393216p13.11
GeneFamilyWASH complex

WASHC2C WASHC2A

1.45e-0465721331
GeneFamilyMyosin heavy chains

MYH8 MYH11

9.99e-04155721098
GeneFamilyINO80 complex |SRCAP complex

INO80C RUVBL2

9.99e-0415572595
CoexpressionGHANDHI_BYSTANDER_IRRADIATION_DN

MYH11 CNTNAP3 SLC5A3

9.00e-0612923M2599
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

PLEKHG1 CNTNAP3B ANO2 ARHGAP26 SETBP1 PCDH15 GARRE1

1.66e-0719393701c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

PLEKHG1 CNTNAP3B ANO2 ARHGAP26 SETBP1 PCDH15 GARRE1

1.66e-071939372531266bc57339d4e2b22a88817008e32b8c1598
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

ATP7A H1-3 H1-4 PHTF2 TOGARAM1 RGL4

9.03e-07155936a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CNTNAP3B MYH11 MYO10 CARMIL1 CNTNAP3 RYR2

2.09e-0617993614fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CNTNAP3B MYH11 MYO10 CARMIL1 SETBP1 CNTNAP3

2.30e-061829367b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ATP7A H1-3 H1-4 PHTF2 TOGARAM1 GARRE1

2.60e-0618693676cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

PBRM1 ALMS1 CCSER2 MARF1 NFAT5 FAM83B

2.60e-0618693603db813598b67b1e08f759758a1c2023396921fa
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

ADRA1A MYO10 SETBP1 PCDH15 RASL12 RYR2

2.69e-06187936e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP3B ANO2 ARHGAP26 SETBP1 CNTNAP3 PCDH15

2.86e-061899367346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

PLEKHG1 ANO2 ARHGAP26 SETBP1 PCDH15 GARRE1

2.86e-0618993675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

PLEKHG1 ANO2 ARHGAP26 SETBP1 PCDH15 GARRE1

2.86e-06189936c81787a8c662db5d7814c583dd64562857629e81
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADRA1A MYO10 SETBP1 PCDH15 RASL12 RYR2

3.22e-0619393699525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADRA1A MYO10 SETBP1 PCDH15 RASL12 RYR2

3.32e-06194936e93de9428c986b8943fc169258847c650cfab0e5
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

ADRA1A MYO10 SETBP1 PCDH15 ABCA10 RYR2

3.42e-06195936603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADRA1A MYO10 SETBP1 PCDH15 ABCA10 RYR2

3.96e-06200936e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCDH15 GNL2 GEMIN5 RASL12 RYR2

2.03e-051589357f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NUSAP1 H1-3 CNTNAP3 H1-4 RGL4

2.88e-05170935cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A MYH11 SETBP1 RASL12 RYR2

3.31e-05175935316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A MYH11 SETBP1 RASL12 RYR2

3.31e-05175935a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B ZC2HC1B STON2 CNTNAP3 PCDH15

3.40e-05176935682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 SETBP1 PCDH15 ABCA10 RYR2

3.89e-051819359ede19228ba5c0668a9c06c915510b95585216ef
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

NUSAP1 RPS19 PRMT7 PTGR3 SLC5A3

4.54e-05187935714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

PLEKHG1 ANO2 PCDH15 KIF4B PRX

4.54e-05187935f3548817f2fded5978137bb252cb628ac199e4f6
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

CNTNAP3B ANO2 ARHGAP26 SETBP1 GARRE1

4.54e-0518793581affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYH11 MYO10 RASL12 RYR2 DYRK2

4.54e-05187935a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

PLEKHG1 CNTNAP3B ANO2 SETBP1 GARRE1

4.66e-05188935eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellFibroblast-E_(Early_Fibroblastic_progenitor)|World / shred on cell class and cell subclass (v4)

NUSAP1 ANO2 H1-2 H1-3 H1-4

4.66e-05188935be3db9768364568f44e32ae6b3bf99e49b0978bb
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO10 SETBP1 PCDH15 RASL12 RYR2

4.78e-051899352a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLEKHG1 CNTNAP3B STON2 CNTNAP3 RAB11FIP5

4.90e-051909356e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ADRA1A SETBP1 PCDH15 ABCA10 RYR2

4.90e-051909353a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADRA1A SETBP1 PCDH15 RASL12 RYR2

5.02e-05191935b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

PLEKHG1 CNTNAP3B ANO2 MYO10 GARRE1

5.02e-05191935c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADRA1A SETBP1 PCDH15 ABCA10 RYR2

5.02e-051919356688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

CNTNAP3B ANO2 SETBP1 CNTNAP3 PCDH15

5.15e-05192935c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A MYH11 CARMIL1 RASL12 RYR2

5.15e-05192935bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADRA1A SETBP1 PCDH15 ABCA10 RYR2

5.15e-0519293599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A MYH11 CARMIL1 RASL12 RYR2

5.15e-05192935b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 CNTNAP3B ANO2 ARHGAP26 PRX

5.15e-05192935c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLEKHG1 CNTNAP3B ANO2 SLC22A8 ARHGAP26

5.28e-05193935ad2df9b77999780860141be6ec366afc0172a331
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 SETBP1 PCDH15 RASL12 RYR2

5.28e-05193935b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

PPP1R3C MYO10 SETBP1 PCDH15 RYR2

5.28e-05193935acad568621ed677031797b8c2e34dafea798d681
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 CNTNAP3B ANO2 ARHGAP26 PRX

5.28e-0519393552e918884877b6659cdca0496390e440f73694a9
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

PLEKHG1 ANO2 SETBP1 PCDH15 GARRE1

5.41e-05194935b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA1A PCDH15 RASL12 ABCA10 RYR2

5.54e-05195935df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHF2 H1-2 H1-3 H1-4 RCBTB2

5.54e-0519593579114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA1A PCDH15 RASL12 ABCA10 RYR2

5.54e-051959354243190ad291d56694e2155954dbaa879c9d3844
ToppCellCOVID-19_Mild-Non-classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

SETBP1 PHTF2 RPS19 TIAM2 RGL4

5.54e-05195935dd00facd20a661ef23fa7fd9a02ee377b8f2d1b9
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

ADRA1A SETBP1 PCDH15 ABCA10 RYR2

5.54e-05195935aa0add081881d349099d12efca5cdee098038d4e
ToppCellCOVID-19_Mild-Non-classical_Monocyte-|COVID-19_Mild / Disease condition and Cell class

SETBP1 PHTF2 RPS19 TIAM2 RGL4

5.54e-051959350295d9897830987eec74f51178e14fb0a83723dc
ToppCellControl-Non-classical_Monocyte-|Control / Disease condition and Cell class

SETBP1 PHTF2 RPS19 VASP RGL4

5.68e-05196935b17ab094cdc7050c2997e24ed474779b5d6f6146
ToppCellControl-Non-classical_Monocyte|Control / Disease condition and Cell class

SETBP1 PHTF2 RPS19 VASP RGL4

5.68e-05196935404064ccfe2cb73df7a7f88aa65d86b97dcef9d4
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADRA1A SETBP1 PCDH15 ABCA10 RYR2

5.68e-051969357d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

ANO2 WASHC2C PCDH15 WASHC2A PRX

5.82e-0519793530dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCellsevere-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NUSAP1 H1-2 H1-3 H1-4 RGL4

5.82e-0519793570704b149b2820b8601d2495b7cd9cbe91eda262
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CNTNAP3B ANO2 SLC22A8 PRX

5.82e-0519793581718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCelldistal-Hematologic-Proliferating_NK/T-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NUSAP1 H1-2 H1-3 H1-4 KIF4B

5.82e-0519793504b10879e48c101d1de449db0bc6b6484090b965
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TBC1D31 H1-2 CCSER2 H1-3 H1-4

5.96e-0519893558d805e827299292750b09c6283fdbe406b75f79
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CNTNAP3B ANO2 PCDH15 PRX

5.96e-051989351d30a1f73b6d6d838f49751402a29c5ef54aa81f
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PPP1R3C MYH11 SETBP1 RABGEF1 RYR2

5.96e-05198935d1827e3707b929e3a3562989a0c11537d344e164
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADRA1A SETBP1 PCDH15 ABCA10 RYR2

5.96e-051989358f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PPP1R3C ADRA1A SETBP1 PCDH15 RYR2

6.25e-05200935aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PPP1R3C ADRA1A SETBP1 PCDH15 RYR2

6.25e-05200935a510deaada669e690329183e18df02870bd204b3
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

NUSAP1 MYO10 H1-2 H1-3 H1-4

6.25e-052009354923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PPP1R3C MYH11 RASL12 RYR2 DYRK2

6.25e-05200935786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

NUSAP1 MYO10 H1-2 H1-3 H1-4

6.25e-05200935dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADRA1A SETBP1 PCDH15 ABCA10 RYR2

6.25e-05200935311fab076f2ceb258e3970eb21e39344b894042a
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

PPP1R3C MYH11 RASL12 RYR2 DYRK2

6.25e-05200935bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PPP1R3C ADRA1A SETBP1 PCDH15 RYR2

6.25e-05200935dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FANCE MYH11 TUB TIAM2

2.17e-041419347ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYH11 H1-3 RASL12 DYRK2

2.17e-04141934a32947b13e888850c979a54c137512e4b96d2f36
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYH11 H1-3 RASL12 DYRK2

2.17e-041419342cb651d63466fdcce011d1dd8de409ef439d03e7
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP20DC PCDH15 ERC2 PTGR3

2.23e-04142934c3a5a80f78704d34db5df85d6e3e8fc84ff24268
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PPP1R3C GARIN5B ANO2 PCDH15

2.68e-04149934c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PPP1R3C GARIN5B ANO2 PCDH15

2.68e-04149934a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

NUSAP1 SOWAHA TBC1D31 FHDC1

2.97e-04153934654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

NUSAP1 SOWAHA TBC1D31 FHDC1

2.97e-04153934105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B ERC2 PFKFB3 RAI2

3.27e-0415793410989c7046fc859f137c7cef3296508d4476f11f
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21B PFKFB3 OSGIN2 TIAM2

3.35e-041589341d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

MYH11 A2ML1 RASL12 RYR2

3.60e-0416193464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP7A CCSER2 HERC2 DYRK2

3.60e-041619345fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellfacs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21B ZC2HC1B OSGIN2 TIAM2

3.69e-04162934484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21B ZC2HC1B OSGIN2 TIAM2

3.69e-04162934bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINE3 C9orf43 GEMIN5 FHDC1

3.77e-04163934953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCelldroplet-Spleen-nan-24m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 SOWAHA H1-2 FHDC1

3.86e-041649344d8233f69ea89d4104caa56bdd0c23c27cabe9b3
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

RPS19 FHDC1 ADTRP TUB

3.95e-04165934ecaeb90a6bc27524ef6f2eefa72aec7315dbde3b
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

PLEKHG1 CNTNAP3B ANO2 SLC22A8

3.95e-0416593484e553d699ac56df89a77248f7308b9133e1b683
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R3C MYH11 TIAM2 DYRK2

4.04e-0416693494a00edf66d54bc5f7343daea700ca26cf38fd90
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 SOWAHA H1-3 H1-4

4.13e-041679341bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21B ALMS1 PRX DYRK2

4.13e-04167934f5bffa77061baec0ba87bd688a047595f32534db
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

C9orf43 CARMIL1 PFKFB3 PRX

4.23e-041689348459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 SOWAHA H1-3 H1-4

4.23e-04168934faaba5ac01c2ebe380f56559374a121979a85a13
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INO80C STON2 GARRE1 PRX

4.32e-041699348a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

MYH11 SETBP1 RASL12 RYR2

4.62e-04172934c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FANCE NUSAP1 CFAP20DC FHDC1

4.62e-04172934e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

MYH11 SETBP1 RASL12 RYR2

4.72e-04173934fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PPP1R3C MYH11 RASL12 RYR2

4.72e-04173934cb6389536195443633adb06e5f1b7483530773d1
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5|TCGA-Lung / Sample_Type by Project: Shred V9

FANCE A2ML1 STON2 FAM83B

5.15e-04177934a0c7d08469c513cecf87777c19876884f1511570
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 CNTNAP3B STON2 CNTNAP3

5.15e-04177934326fde0734ef0d7272693966d346ca479b9d8147
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

NUMA1 CCSER2 MARF1 TUB

5.15e-04177934e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYH11 MYO10 RASL12 RYR2

5.26e-04178934185b44700f06ec58b3c09c80520502166c965fd6
DrugBenfotiamine [22457-89-2]; Down 200; 8.6uM; PC3; HT_HG-U133A

NUSAP1 UBN1 ALMS1 MYO10 ARHGAP26 NUMA1 H1-3 H1-4 NFAT5

1.02e-071949394312_DN
Diseasecreatinine measurement

KIF21B DPAGT1 ALMS1 SETBP1 PHTF2 KYAT3 RASL12 PRMT7 NFAT5 TUB KIAA1614 FAM83B

4.94e-059959012EFO_0004518
DiseaseMyelomonocytic leukemia

ARHGAP26 SETBP1

9.15e-055902C0027019
DiseaseN-acetyltyrosine measurement

ALMS1 RAB11FIP5

1.37e-046902EFO_0020021
DiseaseLeukemia, Myelocytic, Acute

FANCE MYH11 ARHGAP26 SETBP1 H1-2

1.92e-04173905C0023467
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3

2.55e-048902DOID:0060308 (implicated_via_orthology)
DiseaseN-acetylkynurenine (2) measurement

ALMS1 RAB11FIP5

3.27e-049902EFO_0800083
DiseaseN-acetylleucine measurement

ALMS1 RAB11FIP5

3.27e-049902EFO_0800116
DiseaseN-delta-acetylornithine measurement

ALMS1 RAB11FIP5

5.95e-0412902EFO_0800067
Diseaseresponse to calcium channel blocker

MYH11 H1-4 PCDH15

6.77e-0456903EFO_0007767
DiseaseN-acetylglutamine measurement

ALMS1 RAB11FIP5

7.02e-0413902EFO_0800017
Diseaseinositol measurement

MYO10 SETBP1

8.17e-0414902EFO_0010504
Diseaseurinary metabolite measurement

ALMS1 SLC22A8 STON2 RAB11FIP5 KYAT3

9.38e-04245905EFO_0005116
DiseaseN-acetylarginine measurement

ALMS1 RAB11FIP5

1.07e-0316902EFO_0021429
DiseaseMYELODYSPLASTIC SYNDROME

FANCE ARHGAP26 SETBP1

1.14e-0367903C3463824
DiseaseRS-6-hydroxywarfarin measurement

KIF21B INO80C ARHGAP26 RYR2

1.32e-03155904EFO_0803328
DiseaseJuvenile Myelomonocytic Leukemia

ARHGAP26 SETBP1

1.52e-0319902C0349639
Diseasediaphragmatic hernia

PHF2 ERC2

1.86e-0321902EFO_0008561
Diseaseblood urea nitrogen measurement

SETBP1 PHTF2 KYAT3 NFAT5 KIAA1614 FAM83B

2.63e-03452906EFO_0004741
Diseasealcohol use disorder (implicated_via_orthology)

PPP1R3C ADRA1A PBRM1 RYR2

3.04e-03195904DOID:1574 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GASQFETSAAKLKRK

VAMP3

56

Q15836
KRLGSLNKFKAKARS

DDX47

301

Q9H0S4
SGSFVLFLKDGKLKL

CNTNAP3

416

Q9BZ76
NGKLKCAGSSLFLKR

ABCA10

601

Q8WWZ4
FLSDTLSLKGKKLDF

ADGRG4

21

Q8IZF6
AKDFGIKRTIASKVS

ABCB5

276

Q2M3G0
LLKFSREKKAAKTLG

ADRA1A

261

P35348
SKERSGVSLAALKKA

H1-2

51

P16403
KKGLKASFSLSLTFT

A2ML1

511

A8K2U0
KLRKAPVKFASSSSV

ALMS1

3236

Q8TCU4
GLIKLAFLSSKTRCK

CASTOR2

26

A6NHX0
SKKTGLTLLAAASIA

ADTRP

151

Q96IZ2
IKAGGSIAKKFSAAL

ANO2

216

Q9NQ90
KKHSRAATGFLKLLA

DIS3L2

241

Q8IYB7
AKGKTSEALAKLISL

ATP7A

801

Q04656
LKNFISKASRVGAFK

RCBTB2

536

O95199
AGKSALTVKFLTKRF

RASL12

31

Q9NYN1
KGLSGVSTKNFSFKR

RAI2

456

Q9Y5P3
VKKFFSASSRVGSKK

RABGEF1

101

Q9UJ41
AKGFFLRNKLRKSSL

RAB11FIP5

231

Q9BXF6
GFKLSSLLKLADTKA

FHDC1

316

Q9C0D6
ILKLSSARGKAKAFS

OR10AG1

216

Q8NH19
FKGLKRFSLSAKVVD

PBRM1

1271

Q86U86
AKKFSAVRISKGLSE

GNL2

616

Q13823
KKAAGLESAATIRTK

HERC2

2946

O95714
RSSSIASTLGLKKLF

KIAA1614

996

Q5VZ46
SFLKKGSQKLRSLLS

FAM83B

766

Q5T0W9
FKTKSLSFLGTFILK

DPAGT1

321

Q9H3H5
KKKGSSFQTVSALFR

MYH8

641

P13535
LSSRGKKFASALSKF

PFKFB3

271

Q16875
KKGASQSFSKAARLK

KIF21B

901

O75037
AGKTESTKLILKFLS

MYO10

161

Q9HD67
GDFGISKILSSKSKA

NEK8

146

Q86SG6
SSLASAGLKRDSKLK

ERC2

651

O15083
LKGSLKRSAISAAKT

NUSAP1

266

Q9BXS6
IAGSKKKSTRARLVF

NFAT5

401

O94916
KKKKASASSFAQGIS

INO80C

41

Q6PI98
SLKSNKLKSARKFTF

PCDH15

1501

Q96QU1
SVSGLKKIFKLSAAV

OSGIN2

396

Q9Y236
LKIKTASGRKKAFST

OR6N2

226

Q8NGY6
KRDLLIKAGSFKVAT

RGL4

356

Q8IZJ4
KGGLKSVSLFTSKLA

CCSER2

111

Q9H7U1
SSAASHKLLRKIFKA

PRMT7

431

Q9NVM4
SAFISAAKKAKLRSN

FRMPD3

136

Q5JV73
RKNSAVKSKSFLGLS

C9orf43

156

Q8TAL5
GLQKTFSKLTSRFTK

GARRE1

531

O15063
GLFSKFRKSLVSNKV

SQLE

286

Q14534
STRIKKSKALSGFSL

F11

266

P03951
TLLLATSLGKAASKF

MARF1

321

Q9Y4F3
KKKRALASNTSFFSG

KIF4B

1211

Q2VIQ3
SKERSGVSLAALKKA

H1-4

51

P10412
KRDSRKSSGFLNLIK

CARMIL1

1061

Q5VZK9
SKLKRKLSCSFLVGA

CST8

111

O60676
TFLRKSLKAALKHLG

FANCE

521

Q9HB96
ASKERSGVSLAALKK

H1-3

51

P16402
SGKSSKALKILRRVA

SLC22A8

266

Q8TCC7
RGLDALSKKAKASTV

RYR2

431

Q92736
LDASKRAKNFVSSKG

DYRK2

446

Q92630
LSGRAKFLKTISSSK

KYAT3

11

Q6YP21
KFLKTISSSKILGFS

KYAT3

16

Q6YP21
SGSFVLFLKDGKLKL

CNTNAP3B

416

Q96NU0
NSLLRRGASKKALSK

NUMA1

2061

Q14980
FKASGTIKKFRAGLS

PARP6

161

Q2NL67
LSGRAQESKFSKALK

FER1L6

406

Q2WGJ9
DKATGKISKLGRSFT

RUVBL2

196

Q9Y230
FLSGSKKAKNSIDKS

PHTF2

256

Q8N3S3
RALAAFLKKSGKLKV

RPS19

16

P39019
GKEFRLRSAKKASAL

TBC1D31

951

Q96DN5
SFSFSNKKLLGSKAL

PHF2

636

O75151
AKKRVVFADSKGLSL

PPP1R3C

81

Q9UQK1
AATGKLKSFARKFIN

MED24

456

O75448
LISALKNLSSAKRKF

ARHGAP26

46

Q9UNA1
FCGFKSKSLSKRSLR

SLC5A3

661

P53794
KSLKAKVNRGASFGS

STON2

751

Q8WXE9
SLLGKAAKRTSKEYL

CFAP20DC

431

Q6ZVT6
GKAIKLAKDVASLSS

MYH11

1301

P35749
KKGIFSSLKGLDTLA

TIAM2

761

Q8IVF5
DLARGLKKSSSFSKF

SOWAHA

491

Q2M3V2
AGRATKLKVSKFAIS

PRX

951

Q9BXM0
AKVLAKKGDAASLRT

GEMIN5

1056

Q8TEQ6
TKASGATALLLLKRS

SERPINE3

356

A8MV23
SELSKKKASALLFSS

WASHC2C

606

Q9Y4E1
EGKKASKSRLRFSSS

SNX19

716

Q92543
AKLLKKSASVQGFFL

PTGR3

291

Q8N4Q0
ASGAKLRQGFSKSSK

ZC2HC1B

206

Q5TFG8
SELSKKKASALLFSS

WASHC2A

606

Q641Q2
KKSKFSKAGFTALNA

UBN1

216

Q9NPG3
VSKAALATKLLSLSG

TRUB1

56

Q8WWH5
KCSSLKRAKRSTFLG

PLEKHG1

756

Q9ULL1
LRNSAAKKRAKLSGS

TOGARAM1

976

Q9Y4F4
ATSDAVGSSLKKRFK

SETBP1

1386

Q9Y6X0
VFLLAGRKRKKSKTS

TUB

296

P50607
LAAAIAGAKLRKVSK

VASP

226

P50552
KAKALKRSFKSQAVG

GARIN5B

216

Q8N5Q1