Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	telomerase holoenzyme complex	TERT NAT10 DKC1 SMG6	1.27e-05	25	122	4	GO:0005697
Domain	ARM-type_fold	PDS5B USP34 SMG1 HEATR5A FMNL2 FMNL3 ARMC5 LTN1 PDS5A PRKDC EIF4G3 ARMH3 TARBP1	1.89e-07	339	116	13	IPR016024
Domain	HEAT_REPEAT	PDS5B SMG1 HEATR5A PDS5A PRKDC EIF4G3	4.78e-06	70	116	6	PS50077
Domain	ARM-like	PDS5B SMG1 HEATR5A NALF1 ARMC5 LTN1 PDS5A PRKDC TARBP1	4.78e-05	270	116	9	IPR011989
Domain	EGF_CA	FAT3 THBD HEG1 JAG1 ADGRE1 VWA2	1.13e-04	122	116	6	SM00179
Domain	EGF-like_Ca-bd_dom	FAT3 THBD HEG1 JAG1 ADGRE1 VWA2	1.24e-04	124	116	6	IPR001881
Domain	EGF_CA	FAT3 THBD HEG1 JAG1 ADGRE1	1.98e-04	86	116	5	PF07645
Domain	Retinoic_acid_rcpt	RARA RARB	2.28e-04	4	116	2	IPR003078
Domain	EGF_Ca-bd_CS	FAT3 THBD HEG1 JAG1 ADGRE1	3.47e-04	97	116	5	IPR018097
Domain	FATC	SMG1 PRKDC	3.78e-04	5	116	2	PF02260
Domain	EGF_CA	FAT3 THBD HEG1 JAG1 ADGRE1	3.81e-04	99	116	5	PS01187
Domain	ASX_HYDROXYL	FAT3 THBD HEG1 JAG1 ADGRE1	3.99e-04	100	116	5	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT3 THBD HEG1 JAG1 ADGRE1	5.21e-04	106	116	5	IPR000152
Domain	FAT	SMG1 PRKDC	5.64e-04	6	116	2	PS51189
Domain	FATC	SMG1 PRKDC	5.64e-04	6	116	2	PS51190
Domain	FATC_dom	SMG1 PRKDC	5.64e-04	6	116	2	IPR003152
Domain	PIK_FAT	SMG1 PRKDC	5.64e-04	6	116	2	IPR014009
Domain	FATC	SMG1 PRKDC	5.64e-04	6	116	2	SM01343
Domain	EGF	FAT3 THBD HEG1 TIE1 JAG1 ADGRE1 VWA2	6.66e-04	235	116	7	SM00181
Domain	EGF_3	FAT3 THBD HEG1 TIE1 JAG1 ADGRE1 VWA2	6.66e-04	235	116	7	PS50026
Domain	EGF-like_dom	FAT3 THBD HEG1 TIE1 JAG1 ADGRE1 VWA2	9.35e-04	249	116	7	IPR000742
Domain	EGF_1	FAT3 THBD HEG1 TIE1 JAG1 ADGRE1 VWA2	1.07e-03	255	116	7	PS00022
Domain	EGF	THBD HEG1 TIE1 JAG1 VWA2	1.14e-03	126	116	5	PF00008
Domain	EGF-like_CS	FAT3 THBD HEG1 TIE1 JAG1 ADGRE1 VWA2	1.23e-03	261	116	7	IPR013032
Domain	Drf_GBD	FMNL2 FMNL3	1.34e-03	9	116	2	PF06371
Domain	Drf_FH3	FMNL2 FMNL3	1.34e-03	9	116	2	PF06367
Domain	FH3_dom	FMNL2 FMNL3	1.34e-03	9	116	2	IPR010472
Domain	GTPase-bd	FMNL2 FMNL3	1.34e-03	9	116	2	IPR010473
Domain	Drf_FH3	FMNL2 FMNL3	1.34e-03	9	116	2	SM01139
Domain	Drf_GBD	FMNL2 FMNL3	1.34e-03	9	116	2	SM01140
Domain	EGF_2	FAT3 THBD HEG1 TIE1 JAG1 ADGRE1 VWA2	1.34e-03	265	116	7	PS01186
Domain	MFS_1	SLC22A25 MFSD4A SLC22A24 SLC37A2	1.35e-03	77	116	4	PF07690
Domain	MFS	SLC22A25 MFSD4A SLC22A24 SLC37A2	1.35e-03	77	116	4	IPR011701
Domain	ANF_lig-bd_rcpt	CASR GPRC6A GRIK5	1.56e-03	37	116	3	IPR001828
Domain	ANF_receptor	CASR GPRC6A GRIK5	1.56e-03	37	116	3	PF01094
Domain	Peripla_BP_I	CASR GPRC6A GRIK5	1.81e-03	39	116	3	IPR028082
Domain	GBD/FH3_dom	FMNL2 FMNL3	2.03e-03	11	116	2	IPR014768
Domain	GBD_FH3	FMNL2 FMNL3	2.03e-03	11	116	2	PS51232
Domain	NCD3G	CASR GPRC6A	2.85e-03	13	116	2	PF07562
Domain	GPCR_3_9-Cys_dom	CASR GPRC6A	2.85e-03	13	116	2	IPR011500
Domain	Growth_fac_rcpt_	THBD TIE1 JAG1 ADGRE1 CCN3	2.91e-03	156	116	5	IPR009030
Domain	uDENN	DENND1A DENND2C	3.31e-03	14	116	2	SM00800
Domain	GPCR_3_CS	CASR GPRC6A	3.31e-03	14	116	2	IPR017979
Domain	RNaseA	EDDM3A EDDM3B	3.81e-03	15	116	2	IPR001427
Domain	RNaseA_domain	EDDM3A EDDM3B	3.81e-03	15	116	2	IPR023412
Domain	uDENN	DENND1A DENND2C	3.81e-03	15	116	2	PF03456
Domain	FH2	FMNL2 FMNL3	3.81e-03	15	116	2	PS51444
Domain	-	EDDM3A EDDM3B	3.81e-03	15	116	2	3.10.130.10
Domain	PI3/4_kinase_CS	SMG1 PRKDC	3.81e-03	15	116	2	IPR018936
Domain	FH2_Formin	FMNL2 FMNL3	3.81e-03	15	116	2	IPR015425
Domain	FH2	FMNL2 FMNL3	3.81e-03	15	116	2	PF02181
Domain	RnaseA	EDDM3A EDDM3B	3.81e-03	15	116	2	PF00074
Domain	FH2	FMNL2 FMNL3	3.81e-03	15	116	2	SM00498
Domain	DENN	DENND1A DENND2C	4.34e-03	16	116	2	SM00799
Domain	-	SMG1 PRKDC	4.34e-03	16	116	2	1.10.1070.11
Domain	DENN	DENND1A DENND2C	4.34e-03	16	116	2	PF02141
Domain	dDENN	DENND1A DENND2C	4.34e-03	16	116	2	PF03455
Domain	PI3Kc	SMG1 PRKDC	4.34e-03	16	116	2	SM00146
Domain	UDENN	DENND1A DENND2C	4.34e-03	16	116	2	PS50946
Domain	DDENN	DENND1A DENND2C	4.34e-03	16	116	2	PS50947
Domain	dDENN	DENND1A DENND2C	4.34e-03	16	116	2	SM00801
Domain	dDENN_dom	DENND1A DENND2C	4.34e-03	16	116	2	IPR005112
Domain	uDENN_dom	DENND1A DENND2C	4.34e-03	16	116	2	IPR005113
Domain	DENN	DENND1A DENND2C	4.34e-03	16	116	2	PS50211
Domain	DENN_dom	DENND1A DENND2C	4.34e-03	16	116	2	IPR001194
Domain	MFS	SLC22A25 MFSD4A SLC22A24 SLC37A2	4.61e-03	108	116	4	PS50850
Domain	PI3_PI4_kinase	SMG1 PRKDC	5.48e-03	18	116	2	PF00454
Domain	PI3_4_KINASE_1	SMG1 PRKDC	5.48e-03	18	116	2	PS00915
Domain	PI3_4_KINASE_2	SMG1 PRKDC	5.48e-03	18	116	2	PS00916
Domain	PI3/4_kinase_cat_dom	SMG1 PRKDC	5.48e-03	18	116	2	IPR000403
Domain	PI3_4_KINASE_3	SMG1 PRKDC	5.48e-03	18	116	2	PS50290
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PDS5B SMG1 MAP4K3 WDR81 ABCC5 EVA1C THBD IGF2R NOP14 UBR5 SLC7A5 TARBP1 NUP160 MCOLN3	2.78e-07	719	123	14	35337019
Pubmed	Mesenchymal/epithelial regulation of retinoic acid signaling in the olfactory placode.	RARA RARB SHH	8.57e-07	6	123	3	12941622
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PDS5B USP34 STRBP IGF2R NOP14 UBR5 SYNE2 NAT10 PDS5A PRKDC EIF4G3 NUP160	3.75e-06	653	123	12	22586326
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	USP34 ABCC5 SLC6A15 FMNL2 IGF2R FRMD6 UBR5 SLC7A5 PDS5A UBAC2 PRKDC EIF4G3 NUP160	4.02e-06	777	123	13	35844135
Pubmed	Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT.	RARA RARB SHH	6.98e-06	11	123	3	18233958
Pubmed	Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation.	RARA RARB SHH	9.28e-06	12	123	3	19325248
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	NEPRO TERT NOP14 UBR5 DKC1 PRKDC NUP160	1.04e-05	210	123	7	16565220
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	USP34 NMD3 LTN1 PDS5A UBAC2 UBE3C NUP160	1.11e-05	212	123	7	33853758
Pubmed	Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps.	RARA RARB SHH	1.20e-05	13	123	3	16916379
Pubmed	Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.	RARA RARB	1.24e-05	2	123	2	29921692
Pubmed	Sonic Hedgehog repression underlies gigaxonin mutation-induced motor deficits in giant axonal neuropathy.	SHH GAN	1.24e-05	2	123	2	31503551
Pubmed	Retinoic acid receptors in normal growth and development.	RARA RARB	1.24e-05	2	123	2	1330302
Pubmed	PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.	PDS5B PDS5A	1.24e-05	2	123	2	31757807
Pubmed	ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia.	FLT3 ULK1	1.24e-05	2	123	2	32393312
Pubmed	Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival.	UBA1 GAN	1.24e-05	2	123	2	16227972
Pubmed	Regulation of telomerase by telomeric proteins.	TERT DKC1	1.24e-05	2	123	2	15189140
Pubmed	BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice.	TNFSF13B PRKDC	1.24e-05	2	123	2	24435807
Pubmed	The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis.	TERT SMG6	1.24e-05	2	123	2	22011238
Pubmed	A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.	FMNL2 FMNL3	1.24e-05	2	123	2	31751425
Pubmed	Human epididymal proteins and sperm function during fertilization: un update.	EDDM3A EDDM3B	1.24e-05	2	123	2	11715855
Pubmed	Biological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding.	RARA RARB	1.24e-05	2	123	2	24833708
Pubmed	PDS5A and PDS5B in Cohesin Function and Human Disease.	PDS5B PDS5A	1.24e-05	2	123	2	34070827
Pubmed	A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase-deficient human cells.	TERT DKC1	1.24e-05	2	123	2	18057229
Pubmed	Reexpression of retinoic acid receptor (RAR) gamma or overexpression of RAR alpha or RAR beta in RAR gamma-null F9 cells reveals a partial functional redundancy between the three RAR types.	RARA RARB	1.24e-05	2	123	2	7644503
Pubmed	High resolution melting analysis for the identification of novel mutations in DKC1 and TERT genes in patients with dyskeratosis congenita.	TERT DKC1	1.24e-05	2	123	2	22664374
Pubmed	A family with Hoyeraal-Hreidarsson syndrome and four variants in two genes of the telomerase core complex.	TERT DKC1	1.24e-05	2	123	2	23335200
Pubmed	Defects in mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain.	TERT DKC1	1.24e-05	2	123	2	22855157
Pubmed	Interactions between retinoic acid, nerve growth factor and sonic hedgehog signalling pathways in neurite outgrowth.	RARB SHH	1.24e-05	2	123	2	16860305
Pubmed	GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells.	TERT DKC1	1.24e-05	2	123	2	26571381
Pubmed	PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome.	PDS5B PDS5A	1.24e-05	2	123	2	35986423
Pubmed	Increased myoendothelial feedback is associated with increased connexin37 and IK1 channel expression in mesenteric arteries of diet-induced hyperhomocysteinemic mice.	GJA4 KCNN4	1.24e-05	2	123	2	28857417
Pubmed	Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations.	RARA RARB	1.24e-05	2	123	2	9168777
Pubmed	The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita.	TERT DKC1	1.24e-05	2	123	2	22058290
Pubmed	Endothelium-dependent vasodilation in human mesenteric artery is primarily mediated by myoendothelial gap junctions intermediate conductance calcium-activated K+ channel and nitric oxide.	GJA4 KCNN4	1.24e-05	2	123	2	21172909
Pubmed	Retinoic acid regulates gene expression of retinoic acid receptors alpha, beta and gamma in F9 mouse teratocarcinoma cells.	RARA RARB	1.24e-05	2	123	2	1334013
Pubmed	FMNL formins boost lamellipodial force generation.	FMNL2 FMNL3	1.24e-05	2	123	2	28327544
Pubmed	Protein N-myristoylation is required for cellular morphological changes induced by two formin family proteins, FMNL2 and FMNL3.	FMNL2 FMNL3	1.24e-05	2	123	2	22790947
Pubmed	Purification and crystallization of the heterodimeric complex of RARbeta and RXRalpha ligand-binding domains in the active conformation.	RARA RARB	1.24e-05	2	123	2	15159591
Pubmed	[The significance of expression of isoforms RARa1 and RARa2 in response to medicinal therapy and in evaluation of total survival of patients with primarily detected multiple myeloma].	RARA RARB	1.24e-05	2	123	2	30601638
Pubmed	Calcium-sensing receptor bridges calcium and telomerase reverse transcriptase in gastric cancers via Akt.	CASR TERT	1.24e-05	2	123	2	31650467
Pubmed	Retinoic acid receptor beta and telomerase catalytic subunit expression in bronchial epithelium of heavy smokers.	RARB TERT	1.24e-05	2	123	2	12529350
Pubmed	Histone acetyltransferase hALP and nuclear membrane protein hsSUN1 function in de-condensation of mitotic chromosomes.	SUN1 NAT10	1.24e-05	2	123	2	17631499
Pubmed	Association between nuclear expression of retinoic acid receptor alpha and beta and clinicopathological features and prognosis of advanced non-small cell lung cancer.	RARA RARB	1.24e-05	2	123	2	27306217
Pubmed	Anticancer effect of retinoic acid via AP-1 activity repression is mediated by retinoic acid receptor alpha and beta in gastric cancer cells.	RARA RARB	1.24e-05	2	123	2	12009305
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDS5B SMG1 PCDHGA9 STRBP ABCC5 SCML4 OR13D1 NOP14 SYNE2 DKC1 SLC7A5 PRKDC ULK1 EIF4G3 DNAH6 MNDA ZNF292	1.34e-05	1442	123	17	35575683
Pubmed	Retinoic acid induces prostatic bud formation.	RARA RARB SHH	1.53e-05	14	123	3	18393306
Pubmed	LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.	ABCC5 SLC7A5 ABCC10	1.90e-05	15	123	3	28112518
Pubmed	External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium.	RARA RARB SHH	2.34e-05	16	123	3	11795391
Pubmed	Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation.	TERT NAT10 DKC1	2.83e-05	17	123	3	18082603
Pubmed	Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.	SMG1 F11R TIE1	2.83e-05	17	123	3	10428027
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	PDS5B ENDOD1 SUN1 WRNIP1 SLC6A15 NMD3 IGF2R UBR5 PDS5A UBAC2 PRKDC EIF4G3 TARBP1	3.07e-05	942	123	13	31073040
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP34 SUN1 LTN1 ULK1 SMG6	3.08e-05	101	123	5	9872452
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ENDOD1 SLC26A2 ABCC5 SLC6A15 FMNL2 THBD IGF2R F11R JAG1 SLC7A5	3.65e-05	569	123	10	30639242
Pubmed	Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita.	TERT DKC1	3.71e-05	3	123	2	33003434
Pubmed	Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants.	RARA RARB	3.71e-05	3	123	2	7607068
Pubmed	Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.	RARA RARB	3.71e-05	3	123	2	7607067
Pubmed	Impaired distribution of retinoic acid receptors in the hindgut-tailgut region of murine embryos with anorectal malformations.	RARA RARB	3.71e-05	3	123	2	11172439
Pubmed	Cloning of several genes coding for retinoic acid nuclear receptors in the mouse embryonal carcinoma cell line PCC7-MZ1.	RARA RARB	3.71e-05	3	123	2	8383767
Pubmed	Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors.	CASR GPRC6A	3.71e-05	3	123	2	23271661
Pubmed	Retinoic acid receptor gamma: specific immunodetection and phosphorylation.	RARA RARB	3.71e-05	3	123	2	1655807
Pubmed	Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart.	RARA RARB	3.71e-05	3	123	2	9659935
Pubmed	Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity.	RARA RARB	3.71e-05	3	123	2	11245412
Pubmed	mRNA expression pattern of retinoic acid and retinoid X nuclear receptor subtypes in human thyroid papillary carcinoma.	RARA RARB	3.71e-05	3	123	2	23969901
Pubmed	Protein composition of catalytically active human telomerase from immortal cells.	TERT DKC1	3.71e-05	3	123	2	17395830
Pubmed	Altered expression of retinoic acid (RA) receptor mRNAs in the fetal mouse secondary palate by all-trans and 13-cis RAs: implications for RA-induced teratogenesis.	RARA RARB	3.71e-05	3	123	2	10100049
Pubmed	Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation.	RARA SHH	3.71e-05	3	123	2	19029980
Pubmed	Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues.	RARA RARB	3.71e-05	3	123	2	1283441
Pubmed	Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs.	RARA RARB	3.71e-05	3	123	2	36446525
Pubmed	DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase.	TERT PRKDC	3.71e-05	3	123	2	15190070
Pubmed	Function of human epididymal proteins in sperm maturation.	EDDM3A EDDM3B	3.71e-05	3	123	2	9739419
Pubmed	Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.	RARA RARB	3.71e-05	3	123	2	15528208
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SUN1 SYNE2	3.71e-05	3	123	2	16079285
Pubmed	Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes.	RARA RARB	3.71e-05	3	123	2	1655630
Pubmed	B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF.	RTN4RL1 TNFSF13B	3.71e-05	3	123	2	33536561
Pubmed	Immunolocalization of retinoic acid receptors in rat, mouse and human ovary and uterus.	RARA RARB	3.71e-05	3	123	2	8136307
Pubmed	Pds5 Regulates Sister-Chromatid Cohesion and Chromosome Bi-orientation through a Conserved Protein Interaction Module.	PDS5B PDS5A	3.71e-05	3	123	2	28343969
Pubmed	Retinoic acid and mouse skin morphogenesis. I. Expression pattern of retinoic acid receptor genes during hair vibrissa follicle, plantar, and nasal gland development.	RARA RARB	3.71e-05	3	123	2	8027572
Pubmed	Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin.	RARA RARB	3.71e-05	3	123	2	2544807
Pubmed	[Genetic expression and morphogenesis of the skin in vertebrates].	RARA RARB	3.71e-05	3	123	2	8099268
Pubmed	Characterization of retinoic acid receptor-deficient keratinocytes.	RARA RARB	3.71e-05	3	123	2	10748128
Pubmed	Strain difference and mode of inheritance of the susceptibility to passive cutaneous anaphylaxis mediated by allogeneic IgE antibody in the mouse.	RARA RARB	3.71e-05	3	123	2	2737701
Pubmed	Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.	RARA RARB	3.71e-05	3	123	2	29848550
Pubmed	PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model.	FLT3 RARA	3.71e-05	3	123	2	12060771
Pubmed	The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme.	TERT DKC1	3.71e-05	3	123	2	21846770
Pubmed	Spermatid perinuclear RNA-binding protein promotes UBR5-mediated proteolysis of Dicer to accelerate triple-negative breast cancer progression.	STRBP UBR5	3.71e-05	3	123	2	38280476
Pubmed	Mutations of telomerase complex genes linked to bone marrow failures.	TERT DKC1	3.71e-05	3	123	2	17625368
Pubmed	Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins.	SUN1 SYNE2	3.71e-05	3	123	2	19843581
Pubmed	A redundant oncogenic potential of the retinoic receptor (RAR) alpha, beta and gamma isoforms in acute promyelocytic leukemia.	RARA RARB	3.71e-05	3	123	2	17252005
Pubmed	Retinoic acid down-regulation of fibronectin and retinoic acid receptor alpha proteins in NIH-3T3 cells. Blocks of this response by ras transformation.	RARA RARB	3.71e-05	3	123	2	8626453
Pubmed	Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.	FMNL2 FMNL3	3.71e-05	3	123	2	12684686
Pubmed	Function of retinoic acid receptor gamma in the mouse.	RARA RARB	3.71e-05	3	123	2	8388780
Pubmed	Retinoids and vertebrate development.	RARA RARB	3.71e-05	3	123	2	7910825
Pubmed	Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo.	RARA RARB	3.71e-05	3	123	2	10842077
Pubmed	Both retinoic acid receptors alpha (RARalpha) and gamma (RARgamma) are able to initiate mouse upper-lip skin glandular metaplasia.	RARA RARB	3.71e-05	3	123	2	9699718
Pubmed	Mammalian hexokinase 1: evolutionary conservation and structure to function analysis.	RARA RARB	3.71e-05	3	123	2	1783373
Pubmed	Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.	PDS5B PDS5A	3.71e-05	3	123	2	24141881
Pubmed	Association of retinoic acid receptor genes with meningomyelocele.	RARA RARB	3.71e-05	3	123	2	21254357
Pubmed	Arg278, but not Lys229 or Lys236, plays an important role in the binding of retinoic acid by retinoic acid receptor gamma.	RARA RARB	3.71e-05	3	123	2	9852056
Pubmed	A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice.	TERT DKC1	3.71e-05	3	123	2	18626023
Pubmed	Differential expression of retinoic acid receptors in normal and malignant esophageal tissues.	RARA RARB	3.71e-05	3	123	2	15255287
Interaction	C3orf18 interactions	PDS5B SMG1 LTN1 PDS5A PRKDC ARMH3 TARBP1	4.58e-06	115	116	7	int:C3orf18
Interaction	TNFSF13B interactions	USP34 GRAMD1B MALT1 TNFSF13B PDS5A PRKDC UBE3C	5.74e-06	119	116	7	int:TNFSF13B
Cytoband	1p34-p33	B4GALT2 TIE1	4.26e-05	4	123	2	1p34-p33
Cytoband	11q14.3	FAT3 TRIM49C TRIM49D1	8.79e-05	32	123	3	11q14.3
GeneFamily	Calcium sensing receptors	CASR GPRC6A	2.03e-05	2	82	2	279
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	SELPLG FLT3 THBD IGF2R F11R TNFSF13B JAG1 SLC7A5 IL5RA	7.28e-05	394	82	9	471
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	FLT3 LMTK2 TIE1	7.87e-04	40	82	3	321
GeneFamily	ATP binding cassette subfamily C	ABCC5 ABCC10	1.53e-03	13	82	2	807
GeneFamily	Immunoglobulin like domain containing	FLT3 MALT1 F11R TIE1 IGSF21	1.85e-03	193	82	5	594
GeneFamily	Solute carriers	SLC22A25 SLC26A2 SLC6A15 SLC34A3 SLC22A24 SLC7A5 SLC37A2	2.10e-03	395	82	7	752
GeneFamily	Beta 4-glycosyltransferases	B4GALT2 B4GALNT1	2.64e-03	17	82	2	425
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HENDO	MAP4K3 SLC26A2 TMC6 TTYH2 FMNL3 MALT1 GJA4 THBD HEG1 F11R TIE1 FRMD6 SH3TC1 SRGN JAG1 DENND2C SLC7A5 VWA2	1.23e-07	888	120	18	M39049
Coexpression	GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP	SUN1 UBA1 UBR5 NAT10 LTN1 TARBP1 MCOLN3	1.98e-05	180	120	7	M357
Coexpression	GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP	SELPLG ABCC5 IGF2R TNFSF13B UBE3C MNDA CCN3	3.32e-05	195	120	7	M5334
Coexpression	GSE3982_EOSINOPHIL_VS_BCELL_UP	GRIK5 DENND1A F11R JAG1 ULK1 MCOLN3 CCN3	3.77e-05	199	120	7	M5406
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PDS5B USP34 DNAJC2 MALT1 HEG1 IGF2R NALF1 UBR5 SYNE2 LTN1 PDS5A EIF4G3 NUP160 ZNF292	3.83e-05	856	120	14	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN	PDS5B DNAJC2 MALT1 HEG1 NALF1	4.28e-05	84	120	5	M13008
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMG1 SLC26A2 SUN1 ARHGEF38 LMTK2 MFSD4A DENND2C ULK1	3.51e-08	179	122	8	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EVA1C GJA4 HEG1 F11R TIE1 SRGN JAG1 KCNN4	5.13e-08	188	122	8	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	Bronchus_Control_(B.)-Immune-TX-DCs\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	FLT3 TTYH2 FMNL3 MALT1 SRGN TNFSF13B IGSF21 MNDA	8.27e-08	200	122	8	e0beacb88bbdc353a3e883171613027feafcf1ef
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EVA1C GJA4 THBD HEG1 TIE1 SRGN JAG1	6.16e-07	178	122	7	5f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVA1C GJA4 THBD HEG1 TIE1 SRGN JAG1	6.89e-07	181	122	7	0ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EVA1C GJA4 HEG1 TIE1 SRGN JAG1 KCNN4	8.57e-07	187	122	7	66ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RARB EVA1C THBD HEG1 NALF1 TIE1 SRGN	8.88e-07	188	122	7	5eb107122064f0a99dfd445cc87d3766f7257216
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVA1C GJA4 THBD HEG1 TIE1 JAG1 CCN3	9.53e-07	190	122	7	ec6b8e2852e1cce0217ff61243defe98b2351640
ToppCell	P03-Endothelial-large_vessel_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EVA1C GJA4 HEG1 TIE1 SRGN JAG1 KCNN4	9.88e-07	191	122	7	b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EVA1C GJA4 HEG1 TIE1 SRGN JAG1 KCNN4	9.88e-07	191	122	7	d162917816dd2e4767c97447c1cddae9397713ab
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 THBD HEG1 F11R TIE1 SRGN SLC7A5	1.06e-06	193	122	7	e4b440d50ae7391b26924778be6d9d53e0692449
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 THBD HEG1 F11R TIE1 SRGN SLC7A5	1.06e-06	193	122	7	e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EVA1C GJA4 HEG1 NALF1 TIE1 SRGN JAG1	1.06e-06	193	122	7	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 THBD HEG1 F11R TIE1 SRGN SLC7A5	1.06e-06	193	122	7	1772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EVA1C GJA4 THBD HEG1 TIE1 SRGN JAG1	1.10e-06	194	122	7	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GJA4 THBD HEG1 TIE1 SRGN JAG1 CCN3	1.13e-06	195	122	7	75db19c0371320ea5fce1d6de8c1b40b1e6a2e58
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVA1C GJA4 THBD HEG1 TIE1 JAG1 CCN3	1.13e-06	195	122	7	b0979c1b5e4576468b8fe4e9027650859e598b34
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	STRBP GJA4 HEG1 TIE1 JAG1 SYNE2 CCN3	1.34e-06	200	122	7	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TTYH2 DENND1A SH3TC1 SRGN SLC37A2 IGSF21 MNDA	1.34e-06	200	122	7	46f9c28b24e39acdf0481a02b6eb86ecdd83c504
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MFSD4A GJA4 HEG1 TIE1 JAG1 SYNE2 CCN3	1.34e-06	200	122	7	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLT3 DENND1A GRAMD1B SH3TC1 SRGN SLC37A2 MNDA	1.34e-06	200	122	7	b4277b6faa69f20974696c7c422311f5c89e3663
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLT3 RARB GRAMD1B THBD NALF1 IL5RA	2.77e-06	143	122	6	d0ed8c25da1327085e042c2e03cb7503e2c52ce0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLT3 RARB GRAMD1B THBD NALF1 IL5RA	2.77e-06	143	122	6	8900b92a24289204b9ec7baccc11594fec7694f1
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH2 WDR81 SCML4 SH3TC1 NAT10 MCOLN3	5.29e-06	160	122	6	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG TERT DENND2C KCNN4 MNDA IL5RA	5.29e-06	160	122	6	94e4f5fc2156dd8163811c3b8b0781ea9b3f2e06
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GJA4 ARHGDIG HEG1 TIE1 SRGN JAG1	5.69e-06	162	122	6	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	wk_15-18-Hematologic-Myeloid-Promyelocyte-like\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SELPLG RNF222 SRGN AP5B1 TNFSF13B MNDA	8.56e-06	174	122	6	1c0c04c37bfdbdb47bda57784734e0c5f1e8ed87
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-5\|TCGA-Breast / Sample_Type by Project: Shred V9	SLC22A25 DSC1 PPY2P SLC22A24 EDDM3A	8.68e-06	101	122	5	f4db710b2510cdbee26dd5c3b581c85fe6f0be00
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 FAT3 TTYH2 ABCC5 PPY SLC7A5	8.84e-06	175	122	6	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GJA4 THBD HEG1 TIE1 SRGN JAG1	9.43e-06	177	122	6	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EVA1C GJA4 HEG1 NALF1 TIE1 JAG1	1.11e-05	182	122	6	345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 THBD HEG1 TIE1 SRGN JAG1	1.14e-05	183	122	6	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1\|GI_small-bowel / Manually curated celltypes from each tissue	FLT3 TTYH2 FMNL2 THBD PPY MNDA	1.18e-05	184	122	6	8e393eea7240584a3cef718bee094e2705ec1891
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVA1C GJA4 HEG1 TIE1 JAG1 CCN3	1.18e-05	184	122	6	842473fa415575441b595073a994b6d621169776
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 GJA4 THBD TIE1 SRGN AP5B1	1.21e-05	185	122	6	512a195ebbae445afe3722a3943020080daf2f3c
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MFSD4A GJA4 F11R TIE1 SH3TC1 SRGN	1.29e-05	187	122	6	29b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	EVA1C NALF1 TIE1 SRGN JAG1 SYNE2	1.29e-05	187	122	6	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SLC22A25 SLC22A24 GJA4 THBD TIE1 SH3TC1	1.33e-05	188	122	6	b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL3 EVA1C GJA4 HEG1 TIE1 SRGN	1.33e-05	188	122	6	c2c51c6526defe2600302901159b8abbb58d7595
ToppCell	facs-Kidney-nan-24m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 THBD HEG1 F11R TIE1 SRGN	1.37e-05	189	122	6	9d02a824bba59ea0660439f0510d843568e9d8c3
ToppCell	facs-Kidney-nan-24m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 THBD HEG1 F11R TIE1 SRGN	1.37e-05	189	122	6	5f8d4b61296c71b32362432a9ce4c1c3aaeb278d
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 HEG1 TIE1 SRGN JAG1 KCNN4	1.37e-05	189	122	6	d17e8467699c7ca7694a313c26111f085df5204e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EVA1C GJA4 THBD HEG1 TIE1 JAG1	1.37e-05	189	122	6	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	facs-Kidney-nan-24m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 THBD HEG1 F11R TIE1 SRGN	1.37e-05	189	122	6	18f82764b32496e54d1a604a531b261651c5e110
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 THBD HEG1 TIE1 SRGN JAG1	1.37e-05	189	122	6	1e1afa66b32ae752c0a42b02b80f10205464569c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 THBD HEG1 TIE1 SRGN JAG1	1.41e-05	190	122	6	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EVA1C THBD HEG1 TIE1 SRGN KCNN4	1.41e-05	190	122	6	e1b721bb74561fe51c53328a0394c9954e489049
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRAMD1B EVA1C GJA4 HEG1 TIE1 JAG1	1.41e-05	190	122	6	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	normal_Lymph_Node-Myeloid_cells-Activated_DCs\|normal_Lymph_Node / Location, Cell class and cell subclass	FLT3 B4GALNT1 TTYH2 FMNL2 TNFSF13B JAG1	1.41e-05	190	122	6	15978ddd37b521343f88b62dad1643077fc22b2b
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RARB RNF222 THBD HEG1 TIE1 SRGN	1.45e-05	191	122	6	fcdf3a747038e346a467eae8b7c293592658b53f
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVA1C GJA4 THBD HEG1 TIE1 SYNE2	1.45e-05	191	122	6	adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GJA4 THBD F11R TIE1 SH3TC1 SRGN	1.45e-05	191	122	6	e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	EVA1C GJA4 HEG1 TIE1 JAG1 KCNN4	1.45e-05	191	122	6	0b022d8b39eac36115b269aac11a5eaa492754cc
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 HEG1 F11R TIE1 SRGN JAG1	1.45e-05	191	122	6	27f23c2254b610abac1a88d0fecff305addde9da
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EVA1C GJA4 HEG1 TIE1 SRGN JAG1	1.50e-05	192	122	6	bacbaef1f230051335f4433e55db07a161b96b4c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HEG1 F11R TIE1 SRGN SLC7A5	1.50e-05	192	122	6	9d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HEG1 F11R TIE1 SRGN SLC7A5	1.50e-05	192	122	6	042391162df2e3d0027688dd14163c4c6821afe0
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 THBD HEG1 TIE1 SRGN SLC7A5	1.50e-05	192	122	6	9ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HEG1 F11R TIE1 SRGN SLC7A5	1.50e-05	192	122	6	71b0bfee0461ff64cef35881db3959c517e9731b
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 THBD HEG1 TIE1 SRGN SLC7A5	1.50e-05	192	122	6	a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 THBD HEG1 TIE1 SRGN SLC7A5	1.50e-05	192	122	6	66defad13bd8e79319741e43ddb056841710b1d7
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL2 GJA4 THBD HEG1 PPY TIE1	1.54e-05	193	122	6	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EVA1C GJA4 THBD HEG1 TIE1 JAG1	1.54e-05	193	122	6	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	PND14-Endothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 THBD HEG1 F11R TIE1 SRGN	1.59e-05	194	122	6	cee89d4340738f09d07a159cd6aeee4300776988
ToppCell	15-Airway-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	GJA4 THBD F11R TIE1 SRGN KCNN4	1.59e-05	194	122	6	ac0e48b0c09a7f57d30dff321b0c30a4c5e16ad9
ToppCell	PND14-Endothelial-Endothelial_blood-vessel\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 THBD HEG1 F11R TIE1 SRGN	1.59e-05	194	122	6	32962060d80f3edffbe9f0ecad3000c3a9817865
ToppCell	15-Airway-Endothelial-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	GJA4 THBD F11R TIE1 SRGN KCNN4	1.59e-05	194	122	6	f3851337a2d17f4acef2cd812a766eb0b503748b
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 THBD HEG1 F11R TIE1 SRGN	1.59e-05	194	122	6	2c78e754cac848fd47172f94e392749eb0ab50d4
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 THBD HEG1 F11R TIE1 SRGN	1.59e-05	194	122	6	92a8e6e3e3f6fd9dacb723b58e7a8b63473e403e
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	FLT3 TTYH2 THBD PPY TNFSF13B MNDA	1.59e-05	194	122	6	e2d9186a7e8d1a4a71d7bd6dba7fc955d55479e6
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GJA4 THBD NALF1 TIE1 SRGN JAG1	1.63e-05	195	122	6	517af3e6784f02c382df6f5691945eefaa9ec4ae
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EVA1C GJA4 HEG1 TIE1 SRGN JAG1	1.63e-05	195	122	6	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	RARB FAT3 F11R SRGN TNFSF13B MCOLN3	1.68e-05	196	122	6	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVA1C THBD HEG1 NALF1 TIE1 CCN3	1.68e-05	196	122	6	a0ba408b802fa6d6e42e6d234b6879fdb1583f81
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	RARB FAT3 F11R SRGN TNFSF13B MCOLN3	1.68e-05	196	122	6	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	Skin-Leukocytes\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	SELPLG B4GALNT1 PPY SH3TC1 SRGN MNDA	1.68e-05	196	122	6	e327a377c70d17912f5fd2a3529f4e88b147c6c7
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVA1C GJA4 THBD HEG1 TIE1 JAG1	1.73e-05	197	122	6	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FMNL2 THBD HEG1 SRGN SYNE2 CCN3	1.73e-05	197	122	6	66339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	FLT3 FMNL2 DENND1A GRAMD1B SRGN MNDA	1.73e-05	197	122	6	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	proximal-3-Hematologic-Myeloid_Dendritic_Type_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT3 MALT1 TNFSF13B SLC7A5 IGSF21 MNDA	1.78e-05	198	122	6	2e07e62ed230763a6859a8ce19429b5ca8b365a6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 THBD HEG1 TIE1 SRGN JAG1	1.78e-05	198	122	6	5e781583908c4ee107d986904a646a7c6b8e3591
ToppCell	proximal-Hematologic-Myeloid_Dendritic_Type_2\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT3 MALT1 TNFSF13B SLC7A5 IGSF21 MNDA	1.78e-05	198	122	6	3b0143efc33486c1e340ca57981c83cf7e2cad29
ToppCell	proximal-Hematologic-Myeloid_Dendritic_Type_2-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT3 MALT1 TNFSF13B SLC7A5 IGSF21 MNDA	1.78e-05	198	122	6	f254287e13328a8f3b14bf4e44736041ad35593e
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DSC1 DENND1A SRGN KCNN4 IGSF21 MNDA	1.78e-05	198	122	6	732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SMG1 SCML4 SYNE2 ZNF292 SMG6	1.83e-05	199	122	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 THBD HEG1 TIE1 SRGN JAG1	1.83e-05	199	122	6	a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 THBD HEG1 TIE1 SRGN JAG1	1.83e-05	199	122	6	9b02acae6325b0ac9642438a4431285ff396e5fe
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	SELPLG THBD IGF2R SRGN TNFSF13B SLC7A5	1.83e-05	199	122	6	2f6074a2fd3323f258be03042f77929640ad0a75
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	USP34 MAP4K3 FMNL2 DENND1A UBR5 EIF4G3	1.83e-05	199	122	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 MFSD4A HEG1 TIE1 UBR5 SYNE2	1.89e-05	200	122	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SUN1 MFSD4A F11R SYNE2 DENND2C GAN	1.89e-05	200	122	6	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GJA4 THBD HEG1 TIE1 SRGN JAG1	1.89e-05	200	122	6	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TTYH2 DENND1A SH3TC1 SRGN IGSF21 MNDA	1.89e-05	200	122	6	ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 THBD HEG1 TIE1 SRGN JAG1	1.89e-05	200	122	6	93e13937ec74418a697c37d56f57509fb2154780
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GJA4 HEG1 TIE1 JAG1 SYNE2 KCNN4	1.89e-05	200	122	6	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELPLG GPR152 WDR81 FMNL3 SH3TC1 SLC37A2	1.89e-05	200	122	6	80e0483d5ab0c6213aae0ec62619f57e6ec0e4c2
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCC5 DENND1A GRAMD1B SLC37A2 IGSF21 MNDA	1.89e-05	200	122	6	78d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	RARB SLC26A2 STRBP SYNE2 ZNF292	3.92e-05	138	122	5	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG FLT3 TCP11 MALT1 PPY	5.65e-05	149	122	5	48fca6ae33d7722c024b43ce04f4dbce7b6b424b
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG FLT3 TCP11 MALT1 PPY	6.21e-05	152	122	5	7e686721b95c837f2b0d5116927c8ecacef055ee
Disease	conotruncal heart malformations, parental genotype effect measurement	SLC22A25 SLC22A24	4.74e-05	3	118	2	EFO_0005939, MONDO_0016581
Disease	17alpha-hydroxypregnanolone glucuronide measurement	SLC22A25 SLC22A24	4.74e-05	3	118	2	EFO_0800363
Disease	Neuralgia-Neuritis, Sciatic Nerve	RARA RARB	9.46e-05	4	118	2	C0751924
Disease	Sciatic Nerve Palsy	RARA RARB	9.46e-05	4	118	2	C0751925
Disease	Sciatic Neuropathy	RARA RARB	9.46e-05	4	118	2	C0149940
Disease	Lesion of Sciatic Nerve	RARA RARB	9.46e-05	4	118	2	C0154748
Disease	Sciatic Neuritis	RARA RARB	9.46e-05	4	118	2	C0242013
Disease	granulocyte percentage of myeloid white cells	FLT3 TCP11 TNFSF13B KCNN4 PRKDC NUP160 ZNF292	1.05e-04	268	118	7	EFO_0007997
Disease	gallbladder carcinoma (is_implicated_in)	TERT UBR5	1.57e-04	5	118	2	DOID:4948 (is_implicated_in)
Disease	hormone measurement, progesterone measurement	SLC22A25 SLC22A24	1.57e-04	5	118	2	EFO_0004730, EFO_0007004
Disease	fas apoptotic inhibitory molecule 3 measurement	GRAMD1B TNFSF13B	1.57e-04	5	118	2	EFO_0802540
Disease	stomach cancer (is_marker_for)	SHH TERT UBR5 SLC7A5 CCN3	2.72e-04	142	118	5	DOID:10534 (is_marker_for)
Disease	X-Linked Dyskeratosis Congenita	TERT DKC1	3.29e-04	7	118	2	C1148551
Disease	pregnanediol-3-glucuronide measurement	SLC22A25 SLC22A24	4.37e-04	8	118	2	EFO_0800341
Disease	platelet crit	FLT3 TMC6 WRNIP1 ABCC5 TERT CNPPD1 TNFSF13B KCNN4 SLC7A5 NUP160 ABCC10 SMG6	4.41e-04	952	118	12	EFO_0007985
Disease	age of onset of childhood onset asthma	TCP11 FMNL2 AP5B1 UBAC2	5.18e-04	92	118	4	OBA_2001015
Disease	cortical thickness	PDS5B B4GALNT1 STRBP FAT3 SHH SLC6A15 FMNL2 DENND1A NALF1 JAG1 EIF4G3 ABCC10 SMG6	5.21e-04	1113	118	13	EFO_0004840
Disease	Dyskeratosis congenita	TERT DKC1	5.60e-04	9	118	2	cv:C0265965
Disease	X-12844 measurement	SLC22A25 SLC22A24	5.60e-04	9	118	2	EFO_0021339
Disease	HOYERAAL-HREIDARSSON SYNDROME	TERT DKC1	6.99e-04	10	118	2	C1846142
Disease	estrogen measurement	SLC22A25 SLC22A24	6.99e-04	10	118	2	EFO_0011007
Disease	basophil count	FLT3 TRIM49C TRIM49D1 SLC7A5 PRKDC EIF4G3 NUP160 IL5RA	7.40e-04	483	118	8	EFO_0005090
Disease	lymphocyte count	FLT3 PCDHGA9 STRBP ABCC5 GRIK5 FMNL2 SCML4 GRAMD1B TNFSF13B JAG1 KCNN4 ADGRE1 VWA2 NUP160 SMG6	7.50e-04	1464	118	15	EFO_0004587
Disease	uric acid measurement	USP34 FAT3 TMC6 LMTK2 RTN4RL1 SLC22A24 KIAA0319 JAG1 SIMC1	7.89e-04	610	118	9	EFO_0004761
Disease	Acute Promyelocytic Leukemia	FLT3 RARA THBD	8.35e-04	46	118	3	C0023487
Disease	eosinophil percentage of leukocytes	RARB CASR TERT SUPT4H1 SRGN UBAC2 PRKDC EIF4G3 IL5RA ZNF292	8.43e-04	746	118	10	EFO_0007991
Disease	atopic eczema, childhood onset asthma, atopic march	SLC6A15 AP5B1	8.52e-04	11	118	2	EFO_0000274, EFO_0007755, MONDO_0005405
Disease	eosinophil count	RARB ABCC5 CASR GRIK5 TERT MALT1 SRGN JAG1 SLC7A5 UBAC2 OR4C13 PRKDC EIF4G3 IL5RA ZNF292	8.85e-04	1488	118	15	EFO_0004842
Disease	lung adenocarcinoma (is_implicated_in)	RARB TERT UBR5	1.00e-03	49	118	3	DOID:3910 (is_implicated_in)
Disease	11beta-hydroxyandrosterone glucuronide measurement	SLC22A25 SLC22A24	1.02e-03	12	118	2	EFO_0800573
Disease	amyotrophic lateral sclerosis (biomarker_via_orthology)	RARA IGF2R	1.20e-03	13	118	2	DOID:332 (biomarker_via_orthology)
Disease	aseptic loosening	EDDM3A EDDM3B	1.20e-03	13	118	2	EFO_0010725
Disease	mean corpuscular hemoglobin concentration	PDS5B TMC6 GPR152 ABCC5 TERT UBR5 KCNN4 SLC7A5 PRKDC UBE3C EIF4G3 ABCC10	1.60e-03	1105	118	12	EFO_0004528
Disease	Proteinuria	RARB SMG6	1.61e-03	15	118	2	HP_0000093
Disease	nervousness	DENND1A NUP160	1.83e-03	16	118	2	NCIT_C74532
Disease	Dyskeratosis Congenita	TERT DKC1	1.83e-03	16	118	2	C0265965
Disease	Eye Abnormalities	SHH JAG1	2.07e-03	17	118	2	C0015393
Disease	Acute myeloid leukemia	FLT3 TERT	2.07e-03	17	118	2	cv:C0023467
Disease	LEUKEMIA, ACUTE MYELOID	FLT3 TERT	2.07e-03	17	118	2	601626
Disease	non-lobar intracerebral hemorrhage	RARB SLC6A15 NUP160	2.08e-03	63	118	3	EFO_0010178
Disease	venous thromboembolism	SLC6A15 THBD NALF1 TNFSF13B IGSF21 NUP160 SMG6	2.56e-03	460	118	7	EFO_0004286
Disease	mean platelet volume	PDS5B ENDOD1 PCDHGA9 ABCC5 CASR TERT GRAMD1B NALF1 SYNE2 DENND2C KCNN4	2.64e-03	1020	118	11	EFO_0004584
Disease	temporal lobe epilepsy (is_marker_for)	SHH GRIK5	2.87e-03	20	118	2	DOID:3328 (is_marker_for)
Disease	androsterone glucuronide measurement	SLC22A25 SLC22A24	2.87e-03	20	118	2	EFO_0800317
Disease	basophil percentage of leukocytes	TRIM49D1 ABCC5 PRKDC EIF4G3 IL5RA	2.99e-03	243	118	5	EFO_0007992
Disease	activities of daily living score measurement	RTN4RL1 GRIK5	3.17e-03	21	118	2	EFO_0008451
Disease	neutrophil percentage of leukocytes	FLT3 TERT SCML4 KCNN4 SLC7A5 PRKDC NUP160 ZNF292	3.19e-03	610	118	8	EFO_0007990
Disease	sex interaction measurement, bilirubin measurement	FRMD6 IGSF21	3.48e-03	22	118	2	EFO_0004570, EFO_0008343
Disease	Paroxysmal atrial fibrillation	USP34 SUN1 SYNE2 ARMH3	3.62e-03	156	118	4	C0235480
Disease	familial atrial fibrillation	USP34 SUN1 SYNE2 ARMH3	3.62e-03	156	118	4	C3468561
Disease	Persistent atrial fibrillation	USP34 SUN1 SYNE2 ARMH3	3.62e-03	156	118	4	C2585653
Disease	Headache, type 2 diabetes mellitus	SLC6A15 DENND1A	3.80e-03	23	118	2	HP_0002315, MONDO_0005148
Disease	cortical thickness change measurement, age at assessment	SLC6A15 GRIK5	3.80e-03	23	118	2	EFO_0008007, EFO_0021501
Disease	Lung diseases	TERT IGF2R PRKDC	3.81e-03	78	118	3	C0024115
Disease	Atrial Fibrillation	USP34 SUN1 SYNE2 ARMH3	3.96e-03	160	118	4	C0004238

Protein segments in the cluster

Peptide	Gene	Start	Entry
TLKDCRIFLRKLNCL	nan	421	A8MVM7
LLVRRCTCLLKESAK	SMG6	981	Q86US8
KIWGILLALLCILCR	EDDM3A	6	Q14507
LLALLCILCTLLVQS	EDDM3B	11	P56851
RVCKAVLLLCLLHFL	B4GALT2	11	O60909
ILIVVCLFCLLLVCR	ERVK-18	531	O42043
LCHLCLKTFRTVTLL	CTCFL	286	Q8NI51
RALCALVLLLACASL	B4GALNT1	6	Q00973
CISCILVKTNRVLLV	CASR	691	P41180
KILLNCLCSFITLLR	ARHGEF38	486	Q9NXL2
RKTLDLALSILADCC	ARMC5	126	Q96C12
LKSLCLKLLLCLVTV	ARMH3	156	Q5T2E6
EKLCDRLELASLQCL	DNAJC2	381	Q99543
SKLLLVISCVICFSL	GRAMD1B	621	Q3KR37
RKLLSLQLLLCACTS	NFE4	51	Q86UQ8
MLRKGCCVELLLLLV	RTN4RL1	1	Q86UN2
VRLLVACCLADIFRI	PDS5B	76	Q9NTI5
VRLLVACCLADIFRI	PDS5A	86	Q29RF7
LKAACLDILILRICT	RARA	261	P10276
LKAACLDILILRICT	RARB	261	P10826
SLLVLCGCLVLIVKL	SLC34A3	331	Q8N130
CGCLVLIVKLLNSVL	SLC34A3	336	Q8N130
TLLCHLLILVLICSS	PABIR3	176	Q6P4D5
TCSLLALKRLLCLLP	LTN1	226	O94822
CLARALLTDAKILCI	ABCC10	1391	Q5T3U5
TILVCLDCCIKIVNL	MAP4K3	786	Q8IVH8
CLVELSLALDLCLKV	KIAA0100	196	Q14667
CCTALLVAVVARKLE	KCNN4	276	O15554
RLRLSCLDLEQCSLK	MALT1	66	Q9UDY8
FVILTCLVSLILCIR	MCOLN3	291	Q8TDD5
AVLMLLSKERLLTCC	MFSD4A	236	Q8N468
IVILLCFCKAAELRK	LRRC17	6	Q8N6Y2
VCEKLIRILLEECTS	FSIP2	3756	Q5CZC0
AKVIRALLRILCCLL	ENDOD1	406	O94919
ALLRILCCLLKAICR	ENDOD1	411	O94919
KCQLRGRLVLLCSLL	PCDHGA9	6	Q9Y5G4
TLLKCERCSVLLLED	PDE11A	416	Q9HCR9
ILLCRNKLSCCISII	DEFB125	46	Q8N687
AKLVACLCVLLLTAV	SLC7A5	171	Q01650
LLAALSLDRCLLALC	GPR152	121	Q8TDT2
IILIVLIANCVSCCK	LMTK2	56	Q8IWU2
ALLARLHLLCLLCAE	AP5B1	411	Q2VPB7
LLILGIALIVTCCRK	HEG1	1261	Q9ULI3
LLNCLLLLVSCVVIL	OR4C13	206	Q8NGP0
SCLAVGLALLKRCVL	NOP14	686	P78316
RFILSLASCKKCLVI	NAT10	186	Q9H0A0
LCLSLLLLSTCVALL	PPY	6	P01298
TLCISCILTKSLKIL	GPRC6A	671	Q5T6X5
RCLSLLLLSTCVALL	PPY2P	6	Q9NRI7
QLLCIARALLRHCKI	ABCC5	1336	O15440
CLLFIVVLTLLICHK	FLT3	551	P36888
LISADVLACLLLCRL	SLC37A2	466	Q8TED4
LLVQVCDLLRLKDCH	FRMD6	41	Q96NE9
CIGLALTLCALVIRE	EVA1C	331	P58658
LGSLCQRLVKLSCLL	CNPPD1	221	Q9BV87
ISKVTTLCCLLESLI	DNAH6	1956	Q9C0G6
SLRRCVCLLLAAILD	IGSF21	6	Q96ID5
ICFILLILSLICKIC	IL5RA	351	Q01344
KSLVFATLELCVCIL	HEATR5A	1676	Q86XA9
LRKQCLCLTFLLLHL	CCN3	11	P48745
LLRLALCARVLLADK	ARHGDIG	16	Q99819
KALVLELLAAVCLVR	FMNL3	266	Q8IVF7
LLLLTDLKTLCCEFL	GAN	111	Q9H2C0
CCLILLLFKLLATVS	FAT3	16	Q8TDW7
LSVCHLIRVCASLLL	DENND2C	676	Q68D51
RTKALVLELLAAVCL	FMNL2	261	Q96PY5
RILIICSKLSTLTAC	DENND1A	196	Q8TEH3
LLFSLLVLTLLCDAC	DSC1	16	Q08554
LVLNLLELVHLLCRC	GJA4	221	P35212
ILMLQELLCCRKDVL	HELQ	371	Q8TDG4
ASLICAKAECLLRLE	GRIK5	161	Q16478
CLIVCIERATRLVKS	DKC1	131	O60832
SLCELLRIPNICKRI	SLC22A25	336	Q6T423
LECLCRLLTTIGKDL	EIF4G3	926	O43432
LLLALLCALRAKVCG	JAG1	16	P78504
LLCLFILAILLCSLA	F11R	11	Q9Y624
CEILALLKLVCSDIT	OR13D1	211	Q8NGV5
CLQLRTVDRKLKLVC	MNDA	371	P41218
SLLLVALTCCLLALL	IGF2R	2311	P11717
CHRAIITICRLIGIK	MRPS5	316	P82675
SVKQCLLAILILALV	SELPLG	316	Q14242
KVRKEILTVICCLLA	SLC6A15	491	Q9H2J7
KIFCEVDRSLLCLLC	TRIM49	101	P0CI25
LCLVVALLALLCHLR	THBD	526	P07204
RCLLLVLVSSLLVCS	SHH	6	Q15465
DRLTAIKCCILQVLK	SYNE2	2986	Q8WXH0
GRKIICKLCFLQLAI	SLC22A24	171	Q8N4F4
LLRLLDCCCKTFLLT	NEPRO	146	Q6NW34
ELLCKCVKCILLVAR	SMG1	291	Q96Q15
LLRCKVLEIIFLHSC	SIMC1	716	Q8NDZ2
ELRLCNKLVALLATL	SH3TC1	1151	Q8TE82
KSCVIVLRILRDLCN	STRBP	216	Q96SI9
DVDIARDVICLIKCL	NUP160	596	Q12769
RDVICLIKCLRLIEE	NUP160	601	Q12769
RHLRACLLCSLVKTI	SUPT4H1	11	P63272
CLVLAIATFLLCRSI	ADGRE1	616	Q14246
LRCRRKTVLVLMCIL	PROKR1	276	Q8TCW9
LILTSLAISRICLLC	TAS2R7	46	Q9NYW3
LAISRICLLCVILLD	TAS2R7	51	Q9NYW3
IDQRIHLFLKCCLVL	TCP11	426	Q8WWU5
NLCDLITSLLCLLVL	SLC26A2	301	P50443
IILISLAISRICLLC	TAS2R9	46	Q9NYW1
LAISRICLLCVISLD	TAS2R9	51	Q9NYW1
ILAALLTLVCIRRSC	TIE1	776	P35590
ILDLVICLIACLGLA	TTYH2	221	Q9BSA4
AFCCRSRALLLITLI	RNF222	186	A6NCQ9
LKCSRLVLALALILV	SRGN	6	P10124
KIFCEVDRSLLCLLC	TRIM49C	101	P0CI26
LVLERLALSCVELLL	ZNF292	101	O60281
LATCIELCVKALRLE	ZNF292	346	O60281
NCALKLSLECRVDLL	VWA2	331	Q5GFL6
KLGRHVRALVLELCC	UBA1	1026	P22314
GVLKTLCLEVVLCRV	PRKDC	2391	P78527
AALLSRCRVIVLEKL	WRNIP1	366	Q96S55
KIFCEVDRSLLCLLC	TRIM49D1	101	C9J1S8
CRNLILKLAILGTLC	TMC6	511	Q7Z403
LLTRCLRNICKFLVL	SUN1	281	O94901
CLQLLLKLLNTCRLK	TARBP1	691	Q13395
RLICGRIICLDLKDT	UBAC2	56	Q8NBM4
LRNACIDVLKELVLL	USP34	3046	Q70CQ2
KLLAATLLLALLSCC	TNFSF13B	46	Q9Y275
LRFLAKLCRSLLCDD	SCML4	186	Q8N228
CLKELVARVLQRLCE	TERT	76	O14746
TKCKLCIERRLSALL	ULK1	1031	O75385
ILCVKTISLIALICL	WDR81	1396	Q562E7
CLIVKCTADILLLDT	UBR5	1386	O95071
LFQIKRLMSLCCRLL	UBE3C	141	Q15386
KILLLCLCLILLRVR	SIGLEC16	446	A6NMB1
LLLLVTIAGCARKQC	KIAA0319	11	Q5VV43
RLCNSRLKLCVLVLI	NALF1	411	B1AL88
CALESRELLALCLKK	NMD3	71	Q96D46