Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II complex binding	LEO1 ESRRB PAF1	3.08e-06	39	15	3	GO:0000993
GeneOntologyMolecularFunction	RNA polymerase core enzyme binding	LEO1 ESRRB PAF1	4.78e-06	45	15	3	GO:0043175
GeneOntologyMolecularFunction	RNA polymerase binding	LEO1 ESRRB PAF1	1.46e-05	65	15	3	GO:0070063
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	LEO1 ESRRB PAF1	1.53e-05	66	15	3	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	LEO1 ESRRB PAF1	1.53e-05	66	15	3	GO:0001098
GeneOntologyMolecularFunction	estrogen response element binding	ESRRB ESRRG	2.89e-05	11	15	2	GO:0034056
GeneOntologyMolecularFunction	nuclear steroid receptor activity	ESRRB ESRRG	1.56e-04	25	15	2	GO:0003707
GeneOntologyMolecularFunction	nuclear receptor activity	ESRRB ESRRG	9.09e-04	60	15	2	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	ESRRB ESRRG	9.40e-04	61	15	2	GO:0098531
GeneOntologyMolecularFunction	steroid binding	ESRRB ESRRG	4.37e-03	133	15	2	GO:0005496
GeneOntologyMolecularFunction	protein kinase activator activity	WNK1 ERBB3	5.45e-03	149	15	2	GO:0030295
GeneOntologyMolecularFunction	kinase activator activity	WNK1 ERBB3	6.18e-03	159	15	2	GO:0019209
GeneOntologyMolecularFunction	methyltransferase activity	MTR METTL14	1.09e-02	213	15	2	GO:0008168
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	MTR METTL14	1.19e-02	224	15	2	GO:0016741
GeneOntologyMolecularFunction	carboxylic acid binding	MTR L1CAM	1.35e-02	239	15	2	GO:0031406
GeneOntologyBiologicalProcess	stem cell population maintenance	LEO1 ESRRB METTL14 PAF1	1.55e-05	237	14	4	GO:0019827
GeneOntologyBiologicalProcess	maintenance of cell number	LEO1 ESRRB METTL14 PAF1	1.69e-05	242	14	4	GO:0098727
GeneOntologyBiologicalProcess	endodermal cell fate commitment	LEO1 PAF1	6.51e-05	18	14	2	GO:0001711
GeneOntologyBiologicalProcess	cell-cell adhesion mediated by integrin	WNK1 L1CAM	7.27e-05	19	14	2	GO:0033631
GeneOntologyBiologicalProcess	DNA-templated transcription elongation	LEO1 ZC3H4 PAF1	1.15e-04	144	14	3	GO:0006354
GeneOntologyBiologicalProcess	DNA-templated transcription termination	WNK1 ZC3H4	2.37e-04	34	14	2	GO:0006353
GeneOntologyBiologicalProcess	cell fate commitment involved in formation of primary germ layer	LEO1 PAF1	2.81e-04	37	14	2	GO:0060795
GeneOntologyBiologicalProcess	positive regulation of microtubule polymerization	MAP1B OCLN	2.81e-04	37	14	2	GO:0031116
GeneOntologyBiologicalProcess	endodermal cell differentiation	LEO1 PAF1	2.97e-04	38	14	2	GO:0035987
GeneOntologyBiologicalProcess	gastrulation	LEO1 WNK1 PAF1	3.58e-04	212	14	3	GO:0007369
GeneOntologyBiologicalProcess	positive regulation of microtubule polymerization or depolymerization	MAP1B OCLN	3.63e-04	42	14	2	GO:0031112
GeneOntologyBiologicalProcess	regulation of cell size	MAP1B WNK1 L1CAM	4.27e-04	225	14	3	GO:0008361
GeneOntologyBiologicalProcess	mRNA 3'-end processing	LEO1 PAF1	4.35e-04	46	14	2	GO:0031124
GeneOntologyBiologicalProcess	endoderm formation	LEO1 PAF1	4.94e-04	49	14	2	GO:0001706
GeneOntologyBiologicalProcess	positive regulation of D-glucose import	ERBB3 OCLN	5.14e-04	50	14	2	GO:0046326
GeneOntologyBiologicalProcess	positive regulation of axon extension	MAP1B L1CAM	6.22e-04	55	14	2	GO:0045773
GeneOntologyBiologicalProcess	positive regulation of transmembrane transport	WNK1 ERBB3 OCLN	7.49e-04	273	14	3	GO:0034764
GeneOntologyBiologicalProcess	response to wounding	MAP1B MTR ERBB3 OCLN	8.00e-04	659	14	4	GO:0009611
GeneOntologyBiologicalProcess	positive regulation of D-glucose transmembrane transport	ERBB3 OCLN	8.16e-04	63	14	2	GO:0010828
GeneOntologyBiologicalProcess	axon regeneration	MAP1B MTR	9.78e-04	69	14	2	GO:0031103
GeneOntologyBiologicalProcess	regulation of microtubule polymerization	MAP1B OCLN	9.78e-04	69	14	2	GO:0031113
GeneOntologyBiologicalProcess	positive regulation of calcium-mediated signaling	ERBB3 L1CAM	1.01e-03	70	14	2	GO:0050850
GeneOntologyBiologicalProcess	embryonic morphogenesis	LEO1 WNK1 ESRRB PAF1	1.07e-03	713	14	4	GO:0048598
GeneOntologyBiologicalProcess	neuron projection regeneration	MAP1B MTR	1.34e-03	81	14	2	GO:0031102
GeneOntologyBiologicalProcess	regulation of D-glucose import	ERBB3 OCLN	1.34e-03	81	14	2	GO:0046324
GeneOntologyBiologicalProcess	endoderm development	LEO1 PAF1	1.58e-03	88	14	2	GO:0007492
GeneOntologyBiologicalProcess	cell adhesion mediated by integrin	WNK1 L1CAM	1.69e-03	91	14	2	GO:0033627
GeneOntologyBiologicalProcess	RNA 3'-end processing	LEO1 PAF1	1.96e-03	98	14	2	GO:0031123
GeneOntologyBiologicalProcess	positive regulation of protein polymerization	MAP1B OCLN	2.12e-03	102	14	2	GO:0032273
GeneOntologyBiologicalProcess	D-glucose import	ERBB3 OCLN	2.12e-03	102	14	2	GO:0046323
GeneOntologyBiologicalProcess	regulation of axon extension	MAP1B L1CAM	2.20e-03	104	14	2	GO:0030516
GeneOntologyBiologicalProcess	response to axon injury	MAP1B MTR	2.24e-03	105	14	2	GO:0048678
GeneOntologyBiologicalProcess	regulation of D-glucose transmembrane transport	ERBB3 OCLN	2.24e-03	105	14	2	GO:0010827
GeneOntologyBiologicalProcess	regulation of DNA-templated transcription elongation	LEO1 ZC3H4	2.24e-03	105	14	2	GO:0032784
GeneOntologyBiologicalProcess	negative regulation of cell differentiation	LEO1 ESRRB METTL14 PAF1	2.29e-03	875	14	4	GO:0045596
GeneOntologyBiologicalProcess	regulation of microtubule polymerization or depolymerization	MAP1B OCLN	2.37e-03	108	14	2	GO:0031110
GeneOntologyBiologicalProcess	positive regulation of axonogenesis	MAP1B L1CAM	2.64e-03	114	14	2	GO:0050772
GeneOntologyBiologicalProcess	regulation of cellular component size	MAP1B WNK1 L1CAM	2.69e-03	426	14	3	GO:0032535
GeneOntologyBiologicalProcess	microtubule polymerization	MAP1B OCLN	2.78e-03	117	14	2	GO:0046785
GeneOntologyBiologicalProcess	regulation of calcium-mediated signaling	ERBB3 L1CAM	2.97e-03	121	14	2	GO:0050848
GeneOntologyBiologicalProcess	regulation of extent of cell growth	MAP1B L1CAM	3.01e-03	122	14	2	GO:0061387
GeneOntologyBiologicalProcess	formation of primary germ layer	LEO1 PAF1	3.11e-03	124	14	2	GO:0001704
GeneOntologyBiologicalProcess	transcription elongation by RNA polymerase II	LEO1 PAF1	3.26e-03	127	14	2	GO:0006368
GeneOntologyBiologicalProcess	negative regulation of myeloid cell differentiation	LEO1 PAF1	3.62e-03	134	14	2	GO:0045638
GeneOntologyBiologicalProcess	axon extension	MAP1B L1CAM	3.68e-03	135	14	2	GO:0048675
GeneOntologyBiologicalProcess	nuclear receptor-mediated steroid hormone signaling pathway	ESRRB ESRRG	3.73e-03	136	14	2	GO:0030518
GeneOntologyCellularComponent	Cdc73/Paf1 complex	LEO1 PAF1	1.01e-05	7	15	2	GO:0016593
GeneOntologyCellularComponent	transcription elongation factor complex	LEO1 PAF1	7.24e-04	56	15	2	GO:0008023
GeneOntologyCellularComponent	RNA polymerase II, holoenzyme	LEO1 PAF1	1.82e-03	89	15	2	GO:0016591
GeneOntologyCellularComponent	lateral plasma membrane	ERBB3 OCLN	1.86e-03	90	15	2	GO:0016328
GeneOntologyCellularComponent	nuclear DNA-directed RNA polymerase complex	LEO1 PAF1	2.90e-03	113	15	2	GO:0055029
GeneOntologyCellularComponent	DNA-directed RNA polymerase complex	LEO1 PAF1	3.06e-03	116	15	2	GO:0000428
GeneOntologyCellularComponent	RNA polymerase complex	LEO1 PAF1	3.21e-03	119	15	2	GO:0030880
MousePheno	abnormal neuron differentiation	MAP1B ERBB3 METTL14 L1CAM	9.11e-05	275	13	4	MP:0009937
MousePheno	abnormal cerebral aqueduct morphology	ERBB3 L1CAM	2.77e-04	27	13	2	MP:0005537
MousePheno	abnormal spinal reflex	MAP1B ERBB3 L1CAM	3.08e-04	148	13	3	MP:0012079
MousePheno	abnormal response to tactile stimuli	MAP1B ERBB3 L1CAM	3.08e-04	148	13	3	MP:0005316
MousePheno	abnormal cerebellum morphology	MAP1B ERBB3 L1CAM OCLN	3.46e-04	389	13	4	MP:0000849
MousePheno	abnormal metencephalon morphology	MAP1B ERBB3 L1CAM OCLN	4.63e-04	420	13	4	MP:0000847
MousePheno	abnormal stomach epithelium morphology	ERBB3 OCLN	4.94e-04	36	13	2	MP:0000471
MousePheno	abnormal cerebellum vermis morphology	ERBB3 L1CAM	5.22e-04	37	13	2	MP:0000864
MousePheno	abnormal Schwann cell morphology	ERBB3 L1CAM	5.22e-04	37	13	2	MP:0001106
MousePheno	abnormal PNS glial cell morphology	ERBB3 L1CAM	5.22e-04	37	13	2	MP:0001105
MousePheno	abnormal hindbrain morphology	MAP1B ERBB3 L1CAM OCLN	7.97e-04	485	13	4	MP:0000841
Domain	Oest-rel_rcp	ESRRB ESRRG	1.34e-06	3	13	2	IPR027289
Domain	Oest_rcpt/oest-rel_rcp	ESRRB ESRRG	4.47e-06	5	13	2	IPR024178
Domain	Retinoid-X_rcpt/HNF4	ESRRB ESRRG	2.01e-05	10	13	2	IPR000003
Domain	zf-C4	ESRRB ESRRG	4.55e-04	46	13	2	PF00105
Domain	NUCLEAR_REC_DBD_1	ESRRB ESRRG	4.55e-04	46	13	2	PS00031
Domain	Znf_hrmn_rcpt	ESRRB ESRRG	4.55e-04	46	13	2	IPR001628
Domain	Nuclear_hrmn_rcpt	ESRRB ESRRG	4.55e-04	46	13	2	IPR001723
Domain	ZnF_C4	ESRRB ESRRG	4.55e-04	46	13	2	SM00399
Domain	NUCLEAR_REC_DBD_2	ESRRB ESRRG	4.55e-04	46	13	2	PS51030
Domain	-	ESRRB ESRRG	4.75e-04	47	13	2	1.10.565.10
Domain	Nucl_hrmn_rcpt_lig-bd	ESRRB ESRRG	4.95e-04	48	13	2	IPR000536
Domain	Hormone_recep	ESRRB ESRRG	4.95e-04	48	13	2	PF00104
Domain	HOLI	ESRRB ESRRG	4.95e-04	48	13	2	SM00430
Domain	-	ESRRB ESRRG	6.99e-04	57	13	2	3.30.50.10
Domain	Znf_NHR/GATA	ESRRB ESRRG	7.23e-04	58	13	2	IPR013088
Pathway	WP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	LEO1 ESRRB OCLN PAF1	5.97e-05	301	11	4	MM15983
Pathway	REACTOME_E3_UBIQUITIN_LIGASES_UBIQUITINATE_TARGET_PROTEINS	LEO1 PAF1	5.38e-04	45	11	2	MM15508
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	ESRRB ESRRG	6.12e-04	48	11	2	MM14987
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	ESRRB ESRRG	7.46e-04	53	11	2	M8276
Pathway	REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX	LEO1 PAF1	8.93e-04	58	11	2	M805
Pathway	REACTOME_E3_UBIQUITIN_LIGASES_UBIQUITINATE_TARGET_PROTEINS	LEO1 PAF1	9.24e-04	59	11	2	M27763
Pathway	REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX	LEO1 PAF1	9.24e-04	59	11	2	MM14504
Pathway	REACTOME_PROTEIN_UBIQUITINATION	LEO1 PAF1	1.12e-03	65	11	2	MM15490
Pathway	REACTOME_PROTEIN_UBIQUITINATION	LEO1 PAF1	1.65e-03	79	11	2	M27742
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	LEO1 PAF1	1.73e-03	81	11	2	M865
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	LEO1 PAF1	1.82e-03	83	11	2	MM15314
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	LEO1 ESRRB ESRRG OCLN PAF1	2.55e-03	1387	11	5	M734
Pathway	KEGG_CELL_ADHESION_MOLECULES_CAMS	L1CAM OCLN	4.60e-03	133	11	2	M16476
Pathway	WP_ENDODERM_DIFFERENTIATION	LEO1 PAF1	5.29e-03	143	11	2	M39591
Pubmed	Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR.	ESRRB ESRRG	1.74e-07	2	15	2	10072763
Pubmed	Expression of estrogen-related receptors in ovarian cancer and impact on survival.	ESRRB ESRRG	1.74e-07	2	15	2	34089362
Pubmed	An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells.	ESRRB ESRRG	1.74e-07	2	15	2	19631715
Pubmed	Structural insights into Paf1 complex assembly and histone binding.	LEO1 PAF1	1.74e-07	2	15	2	24038468
Pubmed	Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues.	ESRRB ESRRG	5.21e-07	3	15	2	15598686
Pubmed	Transcriptional activators enhance polyadenylation of mRNA precursors.	LEO1 PAF1	5.21e-07	3	15	2	21329879
Pubmed	Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation.	ESRRB ESRRG	5.21e-07	3	15	2	29888756
Pubmed	Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome.	LEO1 PAF1	1.04e-06	4	15	2	25933433
Pubmed	L1CAM binds ErbB receptors through Ig-like domains coupling cell adhesion and neuregulin signalling.	ERBB3 L1CAM	1.04e-06	4	15	2	22815787
Pubmed	Target specificities of estrogen receptor-related receptors: analysis of binding sequences and identification of Rb1-inducible coiled-coil 1 (Rb1cc1) as a target gene.	ESRRB ESRRG	1.04e-06	4	15	2	18039682
Pubmed	MAP1B is required for Netrin 1 signaling in neuronal migration and axonal guidance.	MAP1B L1CAM	1.04e-06	4	15	2	15186740
Pubmed	Estrogen-related receptors alpha, beta and gamma expression and function is associated with transcriptional repressor EZH2 in breast carcinoma.	ESRRB ESRRG	1.04e-06	4	15	2	29940916
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	LEO1 ESRRB ESRRG PAF1	1.46e-06	203	15	4	22083510
Pubmed	Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.	LEO1 PAF1	1.73e-06	5	15	2	37696373
Pubmed	Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors.	ESRRB ESRRG	1.73e-06	5	15	2	18509053
Pubmed	Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism.	ESRRB ESRRG	1.73e-06	5	15	2	23676496
Pubmed	Parkin degrades estrogen-related receptors to limit the expression of monoamine oxidases.	ESRRB ESRRG	2.60e-06	6	15	2	21177257
Pubmed	Receptor-interacting protein 140 differentially regulates estrogen receptor-related receptor transactivation depending on target genes.	ESRRB ESRRG	2.60e-06	6	15	2	16439465
Pubmed	The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.	LEO1 PAF1	2.60e-06	6	15	2	20541477
Pubmed	Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells.	ESRRB ESRRG	2.60e-06	6	15	2	23836911
Pubmed	Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.	LEO1 PAF1	2.60e-06	6	15	2	18469135
Pubmed	The parafibromin tumor suppressor protein is part of a human Paf1 complex.	LEO1 PAF1	3.64e-06	7	15	2	15632063
Pubmed	PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia.	LEO1 PAF1	3.64e-06	7	15	2	29774127
Pubmed	Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.	LEO1 PAF1	3.64e-06	7	15	2	27749823
Pubmed	Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation.	LEO1 PAF1	3.64e-06	7	15	2	22252316
Pubmed	Histone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription.	LEO1 PAF1	4.85e-06	8	15	2	22451921
Pubmed	The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain.	LEO1 PAF1	4.85e-06	8	15	2	23791194
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	LEO1 MAP1B MTR ZC3H4 ERBB3	5.77e-06	650	15	5	38777146
Pubmed	The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.	LEO1 PAF1	6.24e-06	9	15	2	20178742
Pubmed	Perm1 promotes cardiomyocyte mitochondrial biogenesis and protects against hypoxia/reoxygenation-induced damage in mice.	ESRRB ESRRG	6.24e-06	9	15	2	34029594
Pubmed	The human PAF complex coordinates transcription with events downstream of RNA synthesis.	LEO1 PAF1	6.24e-06	9	15	2	16024656
Pubmed	The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.	LEO1 PAF1	6.24e-06	9	15	2	15923622
Pubmed	Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.	LEO1 WNK1 PAF1	7.21e-06	89	15	3	23891004
Pubmed	Evolutionary divergence of the mouse and human Lgn1/SMA repeat structures.	MAP1B OCLN	7.80e-06	10	15	2	10708519
Pubmed	SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver.	LEO1 PAF1	7.80e-06	10	15	2	21726809
Pubmed	Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.	ERBB3 L1CAM	9.53e-06	11	15	2	25315821
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MAP1B ZC3H4 ESRRB ESRRG PAF1	9.74e-06	724	15	5	36232890
Pubmed	ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control.	ESRRB ESRRG	1.14e-05	12	15	2	36542664
Pubmed	COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth.	MAP1B L1CAM	1.14e-05	12	15	2	17021036
Pubmed	The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.	LEO1 PAF1	1.58e-05	14	15	2	19136632
Pubmed	System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.	LEO1 PAF1	1.82e-05	15	15	2	21406692
Pubmed	Linker Histone H1.2 cooperates with Cul4A and PAF1 to drive H4K31 ubiquitylation-mediated transactivation.	LEO1 PAF1	2.08e-05	16	15	2	24360965
Pubmed	SHP-1 dephosphorylates histone H2B to facilitate its ubiquitination during transcription.	LEO1 PAF1	2.08e-05	16	15	2	35938192
Pubmed	Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.	ESRRB METTL14	2.65e-05	18	15	2	25569111
Pubmed	RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.	LEO1 PAF1	2.65e-05	18	15	2	19410543
Pubmed	Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.	MAP1B L1CAM	2.65e-05	18	15	2	22090513
Pubmed	A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.	LEO1 PAF1	3.63e-05	21	15	2	19345177
Pubmed	Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.	LEO1 PAF1	4.37e-05	23	15	2	16307923
Pubmed	Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation.	ESRRB ESRRG	4.37e-05	23	15	2	24349082
Pubmed	Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity.	LEO1 PAF1	5.61e-05	26	15	2	33298525
Pubmed	Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death.	MAP1B L1CAM	5.61e-05	26	15	2	17875933
Pubmed	Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo.	ESRRB OCLN	6.52e-05	28	15	2	25588837
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	LEO1 MTR WNK1 PAF1	9.52e-05	588	15	4	38580884
Pubmed	Transcriptional analysis of cleft palate in TGFβ3 mutant mice.	L1CAM OCLN	1.02e-04	35	15	2	32913205
Pubmed	Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.	ESRRB ESRRG	1.21e-04	38	15	2	27820600
Pubmed	Proteomic identification of brain proteins that interact with dynein light chain LC8.	MAP1B MTR	1.48e-04	42	15	2	14760703
Pubmed	Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population.	MTR ESRRG	1.55e-04	43	15	2	18510611
Pubmed	Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.	MAP1B ERBB3	1.63e-04	44	15	2	38351062
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	LEO1 PAF1	3.13e-04	61	15	2	20305087
Pubmed	A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.	ESRRB ESRRG	3.67e-04	66	15	2	32212902
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	LEO1 MAP1B	3.78e-04	67	15	2	29254152
Interaction	BMX interactions	LEO1 ERBB3 PAF1	3.77e-05	90	15	3	int:BMX
Interaction	CSNK2A1 interactions	LEO1 ZC3H4 METTL14 L1CAM OCLN PAF1	3.88e-05	956	15	6	int:CSNK2A1
Interaction	POU5F1 interactions	LEO1 ERBB3 ESRRB ESRRG PAF1	4.74e-05	584	15	5	int:POU5F1
Interaction	ERBB2 interactions	CCDC180 ERBB3 ESRRB L1CAM OCLN	4.94e-05	589	15	5	int:ERBB2
Interaction	EEF1A2 interactions	MAP1B FAM177A1 ESRRB METTL14	7.06e-05	316	15	4	int:EEF1A2
Interaction	CDKN2A interactions	MTR CCDC180 ERBB3 METTL14	8.86e-05	335	15	4	int:CDKN2A
Interaction	RPS27 interactions	MAP1B ERBB3 ESRRB METTL14	1.00e-04	346	15	4	int:RPS27
Interaction	TULP3 interactions	WNK1 ESRRG OCLN PAF1	1.00e-04	346	15	4	int:TULP3
Interaction	TUFM interactions	MAP1B ZC3H4 ERBB3 ESRRB METTL14	1.02e-04	686	15	5	int:TUFM
Interaction	PTPN11 interactions	LEO1 ERBB3 METTL14 PAF1	1.27e-04	368	15	4	int:PTPN11
Interaction	SLC3A2 interactions	MAP1B ESRRB METTL14 OCLN	1.33e-04	372	15	4	int:SLC3A2
Interaction	PDHA2 interactions	MAP1B METTL14	1.41e-04	24	15	2	int:PDHA2
Interaction	SYT2 interactions	LEO1 WNK1 PAF1	1.72e-04	150	15	3	int:SYT2
Interaction	SLC25A6 interactions	MAP1B ERBB3 ESRRB METTL14	1.95e-04	411	15	4	int:SLC25A6
Interaction	RPN1 interactions	LEO1 MAP1B ERBB3 METTL14 OCLN	2.27e-04	814	15	5	int:RPN1
Interaction	SLC25A5 interactions	MAP1B ERBB3 ESRRB METTL14	2.34e-04	431	15	4	int:SLC25A5
Interaction	GLUD2 interactions	MAP1B METTL14	2.86e-04	34	15	2	int:GLUD2
Interaction	POLR2G interactions	LEO1 ESRRB PAF1	2.90e-04	179	15	3	int:POLR2G
Interaction	MSL3 interactions	METTL14 PAF1	3.03e-04	35	15	2	int:MSL3
Interaction	SNRPA interactions	LEO1 MAP1B ZC3H4 PAF1	3.58e-04	482	15	4	int:SNRPA
Interaction	TULP2 interactions	LEO1 PAF1	3.77e-04	39	15	2	int:TULP2
Interaction	NR0B1 interactions	ESRRB ESRRG	3.97e-04	40	15	2	int:NR0B1
Interaction	PXK interactions	LEO1 PAF1	4.17e-04	41	15	2	int:PXK
Interaction	SNRPB interactions	LEO1 ZC3H4 METTL14 PAF1	4.67e-04	517	15	4	int:SNRPB
Interaction	PAF1 interactions	LEO1 ZC3H4 PAF1	4.89e-04	214	15	3	int:PAF1
Interaction	CPSF6 interactions	LEO1 ZC3H4 METTL14 PAF1	4.98e-04	526	15	4	int:CPSF6
Interaction	DNAJA1 interactions	MAP1B ERBB3 ESRRB METTL14	5.24e-04	533	15	4	int:DNAJA1
Interaction	POLR2A interactions	LEO1 ZC3H4 ESRRB PAF1	5.35e-04	536	15	4	int:POLR2A
Interaction	RPL23 interactions	MAP1B ERBB3 ESRRB METTL14	5.50e-04	540	15	4	int:RPL23
Cytoband	Ensembl 112 genes in cytogenetic band chr5q13	MAP1B OCLN	1.11e-03	152	15	2	chr5q13
GeneFamily	Tetratricopeptide repeat domain containing\|Paf1/RNA polymerase II complex	LEO1 PAF1	6.05e-06	6	12	2	1029
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MAP1B WNK1 OCLN	2.03e-04	181	12	3	694
GeneFamily	Nuclear hormone receptors	ESRRB ESRRG	4.67e-04	49	12	2	71
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HOMTN	MAP1B ESRRB ESRRG L1CAM	5.73e-05	389	15	4	M39073
Coexpression	RODWELL_AGING_KIDNEY_NO_BLOOD_DN	MTR WNK1 ESRRG	7.64e-05	148	15	3	M11837
Coexpression	RODWELL_AGING_KIDNEY_DN	MTR WNK1 ESRRG	7.64e-05	148	15	3	M5408
Coexpression	GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_UP	ERBB3 ESRRG PAF1	1.86e-04	200	15	3	M5168
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	MTR WNK1 ESRRG	2.09e-04	208	15	3	M39233
Coexpression	GENTILE_UV_RESPONSE_CLUSTER_D2	MAP1B ZC3H4	2.12e-04	38	15	2	M12861
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	ERBB3 ESRRB OCLN	2.15e-04	210	15	3	M2010
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	ERBB3 ESRRB OCLN	2.37e-04	217	15	3	MM861
Coexpression	MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_DN	MTR PAF1	2.60e-04	42	15	2	M1552
CoexpressionAtlas	DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#5_top-relative-expression-ranked_200	ERBB3 L1CAM OCLN	1.27e-06	31	15	3	gudmap_developingKidney_e11.5_ureteric bud_200_k5
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#2_top-relative-expression-ranked_500	ERBB3 L1CAM OCLN	2.18e-05	79	15	3	gudmap_developingKidney_e15.5_cortic collect duct_500_k2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	MAP1B WNK1 ZC3H4 METTL14 PAF1	4.04e-05	595	15	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#1_top-relative-expression-ranked_1000	ERBB3 ESRRG OCLN	4.43e-05	100	15	3	gudmap_developingKidney_e15.5_Proximal Tubules_1000_k1
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_1000	ERBB3 L1CAM OCLN	8.40e-05	124	15	3	gudmap_developingKidney_e15.5_cortic collect duct_1000_k3
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#2_top-relative-expression-ranked_200	L1CAM OCLN	1.27e-04	24	15	2	gudmap_developingKidney_e15.5_cortic collect duct_200_k2
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500	ERBB3 ESRRG L1CAM OCLN	1.30e-04	390	15	4	gudmap_developingKidney_e15.5_cortic collect duct_500
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_1000	ESRRG L1CAM OCLN	1.42e-04	148	15	3	gudmap_kidney_P4_CapMesRenVes_Crym_k3_1000
CoexpressionAtlas	DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_200	ERBB3 L1CAM OCLN	1.85e-04	162	15	3	gudmap_developingKidney_e11.5_ureteric bud_200
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#3_top-relative-expression-ranked_1000	ERBB3 L1CAM OCLN	2.17e-04	171	15	3	gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k3
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_1000	ERBB3 L1CAM OCLN	2.74e-04	185	15	3	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k4
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200	MAP1B L1CAM	6.53e-04	54	15	2	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_200
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG OCLN	4.50e-07	195	15	4	3123e02d2894c83962ba402085b5e6422ebf8c73
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG PAF1	1.17e-05	135	15	3	52b5c664c0b7a303c6084d508748dcb6c38a0c23
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso\|E18.5-samps / Age Group, Lineage, Cell class and subclass	WNK1 ERBB3 OCLN	1.36e-05	142	15	3	77fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCell	RV-16._Neuronal\|RV / Chamber and Cluster_Paper	MAP1B ERBB3 L1CAM	1.70e-05	153	15	3	bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	1.87e-05	158	15	3	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	1.95e-05	160	15	3	03b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERBB3 ESRRG L1CAM	2.10e-05	164	15	3	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	2.25e-05	168	15	3	95dc690c1987b05685d36e6bb20eb79308696e30
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	2.46e-05	173	15	3	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	2.46e-05	173	15	3	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	2.54e-05	175	15	3	787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	2.63e-05	177	15	3	dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	2.72e-05	179	15	3	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	2.81e-05	181	15	3	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	NS-critical-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP1B ESRRG PAF1	2.81e-05	181	15	3	cfc3ed541d93158ce26641ea30b7573d93600a11
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	2.86e-05	182	15	3	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	2.91e-05	183	15	3	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRB L1CAM OCLN	3.05e-05	186	15	3	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MAP1B ESRRG L1CAM	3.05e-05	186	15	3	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.10e-05	187	15	3	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAP1B ESRRG L1CAM	3.10e-05	187	15	3	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.10e-05	187	15	3	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.15e-05	188	15	3	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.15e-05	188	15	3	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	3.15e-05	188	15	3	ccd2541892112a7a303f766adf9a7afeb754498c
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	WNK1 ESRRB ESRRG	3.15e-05	188	15	3	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.20e-05	189	15	3	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.20e-05	189	15	3	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.20e-05	189	15	3	55420853f730b433ef58ac9337ac84ac78a247a0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.20e-05	189	15	3	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.20e-05	189	15	3	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.20e-05	189	15	3	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.25e-05	190	15	3	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.25e-05	190	15	3	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.25e-05	190	15	3	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRB L1CAM OCLN	3.25e-05	190	15	3	68ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRB L1CAM OCLN	3.25e-05	190	15	3	010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.25e-05	190	15	3	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRB L1CAM OCLN	3.30e-05	191	15	3	5a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.30e-05	191	15	3	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRB L1CAM OCLN	3.30e-05	191	15	3	78bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.35e-05	192	15	3	32e4a180037e516c5cc798cd9dada9385e0f43ae
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.35e-05	192	15	3	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	MTR WNK1 ERBB3	3.35e-05	192	15	3	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MTR ESRRB ESRRG	3.51e-05	195	15	3	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MTR ESRRB ESRRG	3.56e-05	196	15	3	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.56e-05	196	15	3	e02301642243df483fd066d978317c113c04692b
ToppCell	ILEUM-non-inflamed-(9)_Enteric_neurons\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAP1B ERBB3 L1CAM	3.56e-05	196	15	3	998aa523555ed6bc9c1b5cacbf7ba77c7b218e6b
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	3.56e-05	196	15	3	e874aa82a20bb59582c8cd7f8d30b2ed02903a85
ToppCell	ILEUM-non-inflamed-(9)_Neuro_cell\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAP1B ERBB3 L1CAM	3.56e-05	196	15	3	2b08cd6730119d5dea0152709ab8de580b66cd3c
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	3.56e-05	196	15	3	eea354bdaf4c558df6a94ec4f2f817f7073821d9
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG OCLN	3.56e-05	196	15	3	1bfc3c85ce9501f52a912e53cbded7de74572b9d
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MAP1B ERBB3 L1CAM	3.62e-05	197	15	3	7870c0651caefb0ed13d9f9dab43b5f24d6a9efc
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MAP1B ERBB3 L1CAM	3.62e-05	197	15	3	b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB ESRRG	3.67e-05	198	15	3	688b0eb5534dde40b8630ab8a3252c816711e02e
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	3.67e-05	198	15	3	52ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCell	Epithelial_cells\|World / lung cells shred on cell class, cell subclass, sample id	ERBB3 FAM177A1 OCLN	3.73e-05	199	15	3	bbe69e44b7970f57628365ae771790f2b13d0cae
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	3.73e-05	199	15	3	47466253069d4b1b8f13ce3210f434e60753b38a
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	3.73e-05	199	15	3	f2410509007d35e948a88f127f613d0119e6a4c4
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	3.79e-05	200	15	3	553e9612874480f4d2a45671462e266cd0a09321
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B ERBB3 L1CAM	3.79e-05	200	15	3	51d20543a9c9330c34c085d9290a1fc8b5bff0d4
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	MAP1B L1CAM	3.39e-04	82	15	2	dadc97c81e44858f60687145316102fc10ecc13e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	MAP1B L1CAM	4.65e-04	96	15	2	56e993d37b7958abe56682422536045550e29b41
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	MAP1B L1CAM	6.31e-04	112	15	2	9c3fb470708e76a8f8a3cb9aa17ab130c60fee11
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P1-P1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	ERBB3 FAM177A1	6.31e-04	112	15	2	67b4d2ecc437398c985e6543b82bb593cb164f7f
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Malignant_Peripheral_Nerve_Sheath_Tumors-6\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ERBB3 L1CAM	7.00e-04	118	15	2	ac4b90010d37f72c393fe29e6b9f16e1c7a338ff
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue-Esophagus_normal_tissue\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	ESRRB ESRRG	7.48e-04	122	15	2	4f091144530ac1e85f7a8296847ec08753156d71
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	ESRRB ESRRG	7.48e-04	122	15	2	9f48ba786d913182021b3e42349fb84934b855b8
ToppCell	Control-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MTR OCLN	8.10e-04	127	15	2	556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue-Esophagus_normal_tissue-2\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	ESRRB ESRRG	8.49e-04	130	15	2	3450b9edc7360f8494b5e2ded3132c508bbc971b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	9.15e-04	135	15	2	88f86bab637f1ca1439c7de2d12be4329cf662b8
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ESRRB ESRRG	9.15e-04	135	15	2	54b2aaf8d322e01a3ff6099c2422d68ecccf96b4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	9.42e-04	137	15	2	85b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	9.83e-04	140	15	2	5e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	1.01e-03	142	15	2	5b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB3 OCLN	1.10e-03	148	15	2	9fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	MAP1B L1CAM	1.10e-03	148	15	2	a1269312903fc27830c1835dabf660c659a711be
ToppCell	368C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ESRRG OCLN	1.11e-03	149	15	2	9286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell	368C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ESRRG OCLN	1.11e-03	149	15	2	f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell	RV-16._Neuronal\|World / Chamber and Cluster_Paper	ERBB3 L1CAM	1.11e-03	149	15	2	3a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCell	Pericytes-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B MTR	1.13e-03	150	15	2	dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 ESRRG	1.16e-03	152	15	2	c21e2152b0130485659051d8fb7fb4589d1ec997
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	1.17e-03	153	15	2	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRB	1.17e-03	153	15	2	98670bbce4a770af244f033cdd2d54db57200ca8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG	1.17e-03	153	15	2	0307f10e772021ae68a42690634df458672a6df9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	1.17e-03	153	15	2	79c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCell	Severe-B_naive-5\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MAP1B OCLN	1.17e-03	153	15	2	44572f87d403e314050ab935d2cd676c33d9c287
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 L1CAM	1.17e-03	153	15	2	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NBPF10 ERBB3	1.20e-03	155	15	2	5fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCell	PCW_13-14-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB3 L1CAM	1.22e-03	156	15	2	8353f98e7d393d4299ed1da8f66cfbc7176df1b5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	1.22e-03	156	15	2	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC180 ESRRB	1.22e-03	156	15	2	d34f386985dd17293b1e320d732ab11b46be76ce
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	1.23e-03	157	15	2	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	Severe-B_naive-5\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MAP1B OCLN	1.23e-03	157	15	2	a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MTR L1CAM	1.23e-03	157	15	2	10989c7046fc859f137c7cef3296508d4476f11f
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LEO1 ESRRG	1.25e-03	158	15	2	7f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG	1.26e-03	159	15	2	c186bf05c61fac348cf41973827cced83fafd58a
ToppCell	Ciliated_cells-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B ESRRG	1.26e-03	159	15	2	0c65ae6140abd48c79b04758a6217709ddd15385
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 ESRRG	1.26e-03	159	15	2	50d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell	Club_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ERBB3 ESRRG	1.26e-03	159	15	2	a7bcff268b1962a561fd2848e01ae16565bce895
Drug	N'-((1E)-(4-(diethylamino)phenyl)methylene)-4-hydroxybenzohydrazide	ESRRB ESRRG	4.05e-07	2	15	2	ctd:C501618
Drug	Id-5	ERBB3 ESRRB ESRRG	1.63e-06	36	15	3	CID000448658
Drug	anastrozole	ERBB3 ESRRB ESRRG	1.77e-06	37	15	3	CID000002187
Drug	Lt 2	MTR WNK1 PAF1	5.31e-06	53	15	3	CID003042936
Drug	propyl	ESRRB ESRRG PAF1	1.29e-05	71	15	3	CID000123145
Drug	hydroxyethylretinamide	ERBB3 ESRRB ESRRG	1.40e-05	73	15	3	CID006437840
Drug	U23,469	ESRRB ESRRG	1.45e-05	9	15	2	CID000161922
Drug	endosulfan	LEO1 ESRRB ESRRG	2.45e-05	88	15	3	CID000003224
Drug	ketononestrol aziridine	ESRRB ESRRG	3.15e-05	13	15	2	CID000130642
Drug	2-phenylindole	ESRRB ESRRG	3.15e-05	13	15	2	CID000013698
Drug	4-HT	ERBB3 ESRRB ESRRG	4.17e-05	105	15	3	CID005284643
Drug	benzophenone-2	ESRRB ESRRG	4.23e-05	15	15	2	CID000008571
Drug	AC1Q7B2S	ESRRB ESRRG	4.23e-05	15	15	2	CID000015019
Drug	TAT-59	ESRRB ESRRG	4.84e-05	16	15	2	CID003034829
Drug	OH-PCB 30	ESRRB ESRRG	4.84e-05	16	15	2	CID000105036
Drug	AC1L2JTN	ESRRB ESRRG	8.45e-05	21	15	2	CID000022150
Drug	indenestrol A	ESRRB ESRRG	8.45e-05	21	15	2	CID000107664
Drug	tamoxifen aziridine	ESRRB ESRRG	9.29e-05	22	15	2	CID003033894
Drug	indenestrol B	ESRRB ESRRG	9.29e-05	22	15	2	CID000114716
Drug	clenbuterol	ESRRB ESRRG PAF1	1.02e-04	142	15	3	CID000002783
Drug	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	MTR ERBB3 ESRRG OCLN	1.10e-04	400	15	4	ctd:C085911
Drug	indole-3-carbinol	ERBB3 ESRRB ESRRG	1.30e-04	154	15	3	CID000003712
Drug	idoxifene	ESRRB ESRRG	1.41e-04	27	15	2	CID003034011
Drug	nafoxidine	ESRRB ESRRG	1.41e-04	27	15	2	CID000004416
Drug	RU 16117	ESRRB ESRRG	1.52e-04	28	15	2	CID000066408
Drug	6 Pl	MTR L1CAM	1.52e-04	28	15	2	CID000449006
Drug	dihydroequilenin	ESRRB ESRRG	1.52e-04	28	15	2	CID000003247
Drug	MCDF	ESRRB ESRRG	1.52e-04	28	15	2	CID000114900
Drug	CDRI-85/287	ESRRB ESRRG	1.63e-04	29	15	2	CID000159508
Drug	hexestrol	ESRRB ESRRG	1.63e-04	29	15	2	CID000003606
Drug	Iodine	MAP1B OCLN	1.63e-04	29	15	2	ctd:D007455
Drug	Tl-I	ESRRB ESRRG	1.63e-04	29	15	2	CID006432721
Drug	LY117018	ESRRB ESRRG	1.63e-04	29	15	2	CID000104946
Drug	alpha-zearalanol	ESRRB ESRRG	1.63e-04	29	15	2	CID000022283
Drug	butyl benzyl phthalate	ESRRB ESRRG	1.99e-04	32	15	2	CID000002347
Drug	schizandrin	ESRRB ESRRG	1.99e-04	32	15	2	CID000023915
Drug	o,p'-DDE	ESRRB ESRRG	1.99e-04	32	15	2	CID000246598
Drug	RU 58668	ESRRB ESRRG	2.11e-04	33	15	2	CID000119604
Drug	AC1L1K7W	ESRRB ESRRG	2.25e-04	34	15	2	CID000005377
Drug	formononetin	ESRRB ESRRG	2.25e-04	34	15	2	CID005280378
Drug	centchroman	ESRRB ESRRG	2.25e-04	34	15	2	CID000035805
Drug	CGS 12066B	MTR PAF1	2.25e-04	34	15	2	CID000002689
Drug	AC1L32HG	ESRRB ESRRG	2.25e-04	34	15	2	CID000107645
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A	MAP1B WNK1 ESRRG	2.53e-04	193	15	3	4321_DN
Drug	A 5791	ESRRB ESRRG	2.66e-04	37	15	2	CID000003408
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A	MAP1B WNK1 ZC3H4	2.73e-04	198	15	3	4282_DN
Drug	FIGLU	MAP1B MTR	2.96e-04	39	15	2	CID000000909
Drug	fadrozole	ESRRB ESRRG	3.11e-04	40	15	2	CID000059693
Drug	arzoxifene	ESRRB ESRRG	3.11e-04	40	15	2	CID000179337
Drug	d-equilenin	ESRRB ESRRG	3.27e-04	41	15	2	CID000010597
Drug	Goserelin	ESRRB ESRRG	3.27e-04	41	15	2	CID000047725
Drug	AC1NDP1R	ESRRB ESRRG	3.44e-04	42	15	2	CID004629338
Drug	exemestane	ESRRB ESRRG	3.60e-04	43	15	2	CID000060198
Drug	n-octylphenol	ESRRB ESRRG	3.60e-04	43	15	2	CID000013700
Drug	lasofoxifene	ESRRB ESRRG	3.77e-04	44	15	2	CID000216416
Drug	ospemifene	ESRRB ESRRG	3.77e-04	44	15	2	CID003036505
Drug	bisphenol A	ERBB3 ESRRB ESRRG	3.87e-04	223	15	3	CID000006623
Drug	triphenylethylene	ESRRB ESRRG	4.12e-04	46	15	2	CID000006025
Drug	K-Cl	MTR ESRRB ESRRG PAF1	4.17e-04	567	15	4	CID000004873
Drug	4-octylphenol	ESRRB ESRRG	4.31e-04	47	15	2	CID000015730
Drug	AC1L2JRI	ERBB3 PAF1	4.31e-04	47	15	2	CID000048279
Drug	Implanon	ESRRB ESRRG	4.31e-04	47	15	2	CID000040976
Drug	NSC9700	ERBB3 ESRRB ESRRG PAF1	4.49e-04	578	15	4	CID000005408
Drug	o,p'-DDT	ESRRB ESRRG	4.68e-04	49	15	2	CID000013089
Drug	EM-652	ESRRB ESRRG	4.68e-04	49	15	2	CID000155435
Drug	p,p'-hydroxy-DDT	ESRRB ESRRG	4.87e-04	50	15	2	CID000076302
Drug	ORG 2058	ESRRB ESRRG	5.07e-04	51	15	2	CID000119086
Drug	N-desmethyl-tamoxifen-hydrochloride	ESRRB ESRRG	5.27e-04	52	15	2	CID000035887
Drug	8-prenylnaringenin	ESRRB ESRRG	5.27e-04	52	15	2	CID000480764
Drug	4-tert-octylphenol	ESRRB ESRRG	5.68e-04	54	15	2	CID000008814
Drug	AC1Q6OQF	ESRRB ESRRG	5.90e-04	55	15	2	CID000009685
Drug	AC1L4WZL	ESRRB ESRRG	5.90e-04	55	15	2	CID000165628
Drug	sodium molybdate	ESRRB ESRRG	6.33e-04	57	15	2	CID000061424
Disease	azoospermia (implicated_via_orthology)	ESRRB ESRRG	7.29e-05	27	14	2	DOID:14227 (implicated_via_orthology)
Disease	interleukin 18 measurement	MAP1B OCLN	5.84e-04	76	14	2	EFO_0004581
Disease	hypothyroidism (biomarker_via_orthology)	MAP1B L1CAM	6.47e-04	80	14	2	DOID:1459 (biomarker_via_orthology)
Disease	pancreatic cancer (is_implicated_in)	MTR L1CAM	1.26e-03	112	14	2	DOID:1793 (is_implicated_in)
Disease	Malignant neoplasm of breast	MTR WNK1 ERBB3 OCLN	1.30e-03	1074	14	4	C0006142
Disease	hypertension (is_implicated_in)	MTR WNK1	1.47e-03	121	14	2	DOID:10763 (is_implicated_in)
Disease	Malignant Neoplasms	ERBB3 OCLN	1.64e-03	128	14	2	C0006826
Disease	Mammary Neoplasms, Human	MTR ERBB3 OCLN	1.76e-03	525	14	3	C1257931
Disease	Mammary Carcinoma, Human	MTR ERBB3 OCLN	1.76e-03	525	14	3	C4704874
Disease	Mammary Neoplasms	MTR ERBB3 OCLN	1.78e-03	527	14	3	C1458155
Disease	Breast Carcinoma	MTR ERBB3 OCLN	1.89e-03	538	14	3	C0678222

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGTEEEDEDEEYEYM	ERBB3	1186	P21860
KEEGLEEIYYEDMES	CCDC180	806	Q9P1Z9
DKELDDYREESEEYM	OCLN	461	Q16625
PQYYEDEFEDEEMLD	LEO1	391	Q8WVC0
AEDAREEEYEPEKME	MAP1B	1026	P46821
EEEYEPEKMEAEDYV	MAP1B	1031	P46821
IDEYYRMKKEEEEEE	FAM177A1	136	Q8N128
YLDEGETDEDKMEEY	METTL14	66	Q9HCE5
EKYDIEFEDKEMAPE	L1CAM	646	P32004
EEEMDYAPDDVYDYK	PAF1	276	Q8N7H5
EDELVYADDYIMDED	ESRRG	321	P62508
DDKLVYAEDYIMDEE	ESRRB	296	O95718
FDMDEIEKYQEVEED	NBPF10	916	Q6P3W6
LKDEYFEEIMEEYED	MTR	901	Q99707
EEDFYEEEMDYGESE	ZC3H4	281	Q9UPT8
EPMGDDDYDEYSKEL	ZC3H4	296	Q9UPT8
APEMYEEKYDESVDV	WNK1	391	Q9H4A3