Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF250 ZNF311 ZNF142 ZNF585A ZNF555 ZNF280D ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 SOX14 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF723 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF345 ZNF585B TBX5	8.91e-20	1459	92	38	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A ZNF555 ZNF280D ZNF569 ZNF846 ZFP1 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 SOX14 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF723 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZFY ZNF260 ZNF345 ZNF585B TBX5	2.41e-18	1412	92	36	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF250 ZNF311 ZNF585A ZNF280D ZNF569 ZNF366 ZFP1 ZNF667 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 SOX14 ZNF736 ZNF81 ZNF221 ZNF224 ZNF723 ZNF782 ZBTB11 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF345 ZNF585B TBX5	2.19e-15	1244	92	31	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF250 ZNF311 ZNF585A ZNF280D ZNF569 ZNF366 ZFP1 ZNF667 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 SOX14 ZNF736 ZNF81 ZNF221 ZNF224 ZNF723 ZNF782 ZBTB11 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF345 ZNF585B TBX5	3.95e-15	1271	92	31	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF585A ZNF624 ZSCAN2 SOX14 ZNF736 ZNF224 ZNF782 ZNF433 ZFY ZNF345 ZNF585B TBX5	9.91e-06	560	92	12	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF585A ZNF624 ZSCAN2 SOX14 ZNF736 ZNF224 ZNF782 ZNF433 ZFY ZNF345 ZNF585B TBX5	1.10e-05	566	92	12	GO:0001216
Domain	zf-C2H2	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF280D ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	6.82e-34	693	88	40	PF00096
Domain	-	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	7.01e-33	679	88	39	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	1.62e-32	694	88	39	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF280D ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	5.46e-32	775	88	40	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF280D ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	6.04e-32	777	88	40	PS00028
Domain	Znf_C2H2-like	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF280D ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	1.55e-31	796	88	40	IPR015880
Domain	Znf_C2H2	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF280D ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	2.40e-31	805	88	40	IPR007087
Domain	ZnF_C2H2	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF280D ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	2.77e-31	808	88	40	SM00355
Domain	zf-C2H2_6	ZNF250 ZNF311 HIC1 ZNF555 ZNF234 ZNF569 ZNF366 ZNF846 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF224 ZNF782 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF260 ZNF345	1.49e-25	314	88	26	PF13912
Domain	KRAB	ZNF250 ZNF311 ZNF585A ZNF555 ZNF234 ZNF569 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZNF420 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZNF25 ZNF568 ZNF426 ZNF433 ZNF222 ZNF585B	1.86e-25	358	88	27	PS50805
Domain	KRAB	ZNF250 ZNF311 ZNF585A ZNF555 ZNF234 ZNF569 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZNF420 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZNF25 ZNF568 ZNF426 ZNF433 ZNF222 ZNF585B	1.86e-25	358	88	27	PF01352
Domain	KRAB	ZNF250 ZNF311 ZNF585A ZNF555 ZNF234 ZNF569 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZNF420 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZNF25 ZNF568 ZNF426 ZNF433 ZNF222 ZNF585B	4.19e-25	369	88	27	SM00349
Domain	KRAB	ZNF250 ZNF311 ZNF585A ZNF555 ZNF234 ZNF569 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZNF420 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZNF25 ZNF568 ZNF426 ZNF433 ZNF222 ZNF585B	4.50e-25	370	88	27	IPR001909
Domain	zf-H2C2_2	ZNF846 ZFP1 ZNF345	3.54e-05	14	88	3	PF13465
Domain	ZnF_BED	ZNF846 ZNF426	1.17e-03	11	88	2	SM00614
Domain	Tyr_kinase_rcpt_2_CS	DDR2 INSR	1.17e-03	11	88	2	IPR002011
Domain	RECEPTOR_TYR_KIN_II	DDR2 INSR	1.40e-03	12	88	2	PS00239
Domain	Znf_BED	ZNF846 ZNF426	1.40e-03	12	88	2	IPR003656
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF250 KMT2C ZNF311 ZNF585A ZNF555 ZNF234 ZNF569 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZNF420 ZNF736 ZNF221 DGCR8 ZNF224 ZNF782 ZFP69 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZNF222 ZNF585B CDC7 TBX5	5.73e-13	1387	66	29	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF250 ZNF585A ZNF569 ZFP1 ZNF667 ZFP28 ZNF624 ZFP14 ZNF420 ZNF736 ZNF221 ZNF782 ZFP69 ZNF25 ZNF426 ZNF433 ZNF585B TBX5	8.48e-09	768	66	18	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZNF250 ZNF585A GTF3A ZNF569 ZFP1 ZNF667 ZFP28 ZNF624 ZFP14 ZNF420 ZNF736 ZNF221 ZNF782 ZFP69 ZNF25 ZNF426 ZNF433 ZNF585B TBX5	1.23e-07	1022	66	19	MM15436
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF250 ZNF311 ZNF555 ZNF569 ZFP1 ZNF620 ZNF624 ZNF736 ZNF57 ZBTB11 ZNF25	2.08e-12	181	92	11	37372979
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF585A ZNF569 ZNF624 ZNF420 ZNF736 ZNF25 ZNF585B	5.64e-11	49	92	7	9630514
Pubmed	Specific and ubiquitous expression of different Zn finger protein genes in the mouse.	ZNF585A ZFP28 ZNF624 ZNF585B	1.59e-09	7	92	4	3143103
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	ZNF585A ZNF280D ZNF569 ZFP1 ZNF620 ZNF568 ZNF585B	2.53e-09	83	92	7	20562864
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF234 ZNF221 ZNF224 ZNF222	2.15e-07	20	92	4	12743021
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF569 ZNF624 ZFP69 ZNF426	2.15e-07	20	92	4	7479878
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF569 ZNF624 ZFP69 ZNF426	2.15e-07	20	92	4	2542606
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	KMT2C HIC1 ZNF585A GTF3A ZMIZ2 ZFP28 ZFP14 ZSCAN2 ZNF25 ZNF426 ZFY ZNF585B	3.85e-07	709	92	12	22988430
Pubmed	Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.	ZNF585A ZNF585B	6.92e-06	2	92	2	37668106
Pubmed	Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase.	PTPN12 INSR	6.92e-06	2	92	2	8454633
Pubmed	TANK-binding kinase 1 mediates phosphorylation of insulin receptor at serine residue 994: a potential link between inflammation and insulin resistance.	TBK1 INSR	6.92e-06	2	92	2	19251743
Pubmed	Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway.	INSR LRP1	2.07e-05	3	92	2	19815552
Pubmed	Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.	ZNF569 ZNF624 ZFP69 ZNF426	2.13e-05	61	92	4	8662221
Pubmed	Tyrosine phosphatases in the HER2-directed motility of ovarian cancer cells: Involvement of PTPN12, ERK5 and FAK.	PTPN12 MAPK7	4.14e-05	4	92	2	21483099
Pubmed	A cohort of balanced reciprocal translocations associated with dyslexia: identification of two putative candidate genes at DYX1.	ZNF280D PDE7B	4.14e-05	4	92	2	20798984
Pubmed	Insulin stimulates movement of sorting nexin 9 between cellular compartments: a putative role mediating cell surface receptor expression and insulin action.	INSR SNX9	4.14e-05	4	92	2	12917015
Pubmed	Ganglioside GM3 depletion reverses impaired wound healing in diabetic mice by activating IGF-1 and insulin receptors.	ST3GAL5 INSR	4.14e-05	4	92	2	24326453
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	GTF3A ZNF280D ZNF569 ZMIZ2 ZFP28 ZBTB41 ZNF25 ZNF426 ZNF260 TBX5	5.62e-05	808	92	10	20412781
Pubmed	HIV-1 Env Glycoprotein Phenotype along with Immune Activation Determines CD4 T Cell Loss in HIV Patients.	CD38 CASP7	6.89e-05	5	92	2	26764036
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZFP1 ZNF224 ZNF25	7.63e-05	31	92	3	2288909
Pubmed	Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.	GTF3A NVL PHF5A OPA1 CDC7	1.05e-04	175	92	5	37866880
Pubmed	Quantitative trait loci for body size components in mice.	TBK1 ZSCAN2 SOX14 TBX5	1.37e-04	98	92	4	16783635
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	AURKC PTPN12 CDC42BPA TBK1 DDR2 INSR MAPK7 SNX9 PDE7B CDC7	1.49e-04	910	92	10	36736316
Pubmed	Characterization of a mouse multigene family that encodes zinc finger structures.	ZFP14 ZNF25	1.92e-04	8	92	2	2452975
Pubmed	Genetic and physical mapping of the dreher locus on mouse chromosome 1.	DDR2 ASTN1	2.46e-04	9	92	2	10444330
Pubmed	N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.	KMT2C KLHL28 ZNF846 ZFP69 ZNF260	2.86e-04	217	92	5	34048709
Pubmed	Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study.	PIWIL4 DGCR8	3.07e-04	10	92	2	20721975
Pubmed	Zinc finger protein genes in the mouse genome.	ZFP1 ZFY	4.49e-04	12	92	2	1797234
Pubmed	Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening.	ZNF827 PIWIL4 SMC5	5.77e-04	61	92	3	35205757
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	HIC1 ZBTB41 ZBTB11	6.34e-04	63	92	3	34351428
Pubmed	Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes.	LRP1 CASP7	7.11e-04	15	92	2	20468060
Pubmed	Protein phosphatase 1α interacting proteins in the human brain.	FRMPD4 ZNF827 ZBTB11	7.59e-04	67	92	3	22321011
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KIF15 ZNF280D ZMIZ2 TBK1 LRP1 ZBTB11	8.69e-04	418	92	6	34709266
Pubmed	Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.	ZNF234 ZNF345	1.41e-03	21	92	2	7865130
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZNF569 ZNF57	1.54e-03	22	92	2	1946370
Pubmed	Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.	ZNF569 ZNF57	1.54e-03	22	92	2	1505991
Pubmed	Chromosomal localization of the genes for five zinc finger proteins expressed in mouse lens.	ZFP1 ZNF260	1.54e-03	22	92	2	7590745
Pubmed	Dgcr8 deletion in the primitive heart uncovered novel microRNA regulating the balance of cardiac-vascular gene program.	DGCR8 TBX5	1.54e-03	22	92	2	30128894
Pubmed	An inter-species protein-protein interaction network across vast evolutionary distance.	ZNF250 ZMIZ2 GRAMD2B MAPK7 SNX9 ZNF426	1.81e-03	483	92	6	27107014
Pubmed	Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation.	MAPK7 TBX5	1.84e-03	24	92	2	26744331
Pubmed	T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number.	CNTFR TBX5	2.00e-03	25	92	2	27046536
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	KMT2C GTF3A ZFP1 GRAMD2B NVL ZNF221 NUDT4B ZNF25 ZNF426 ZNF345	2.22e-03	1293	92	10	15342556
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	ZNF366 LRP1 MAPK7	2.41e-03	100	92	3	25807483
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF280D ZFP14 EPG5	2.48e-03	101	92	3	10997877
Pubmed	The protein interaction landscape of the human CMGC kinase group.	AURKC INSR ZFP14 DGCR8 MAPK7 PDE7B PHF5A	2.50e-03	695	92	7	23602568
Pubmed	Rebalancing gene haploinsufficiency in vivo by targeting chromatin.	KMT2C TBX5	2.50e-03	28	92	2	27256596
Cytoband	19q13.12	ZNF585A ZNF569 ZFP14 ZNF420 ZNF568 ZNF260 ZNF345 ZNF585B	2.05e-12	72	92	8	19q13.12
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	AURKC NLRP9 ZNF585A ZNF234 ZNF569 ZNF667 ZFP28 ZFP14 ZNF420 ZNF221 ZNF224 ZNF568 ZNF260 ZNF222 ZNF345 ZNF585B	1.92e-09	1192	92	16	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF250 ZNF311 HIC1 ZNF142 ZNF585A GTF3A ZNF555 ZNF234 ZNF827 ZNF569 ZNF366 ZNF846 ZFP1 ZNF667 ZNF620 ZFP28 ZNF624 ZFP14 ZSCAN2 ZNF420 ZBTB41 ZNF736 ZNF81 ZNF57 ZNF221 ZNF224 ZNF782 ZFP69 ZBTB11 ZNF25 ZNF568 ZNF426 ZNF433 ZNF691 ZFY ZNF260 ZNF222 ZNF345 ZNF585B	3.52e-35	718	74	39	28
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	HIC1 KLHL28 ZBTB41 ZBTB11	2.22e-03	134	74	4	861
Coexpression	NIKOLSKY_BREAST_CANCER_19Q13.1_AMPLICON	ZNF585A ZNF569 ZNF420 ZNF568 ZNF260 ZNF345 ZNF585B	8.50e-13	22	92	7	M8692
ToppCell	ASK452-Epithelial-Secretory\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	GALNTL6 RGS22 GRAMD2B ZNF57 ZNF782 TBX5	1.78e-06	176	92	6	dd334c8a8a31dc26b2d558df0ef6bed6dc1a6610
ToppCell	COVID-19-APC-like-Monocytes\|COVID-19 / group, cell type (main and fine annotations)	ZNF555 ZNF366 ZNF620 PIWIL4 CDC7	1.93e-05	158	92	5	a0d94bd067424783863a48db20976d4c2043600c
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF846 DDR2 ZFP1 LRP1 MAPK7	2.24e-05	163	92	5	360cd65decda24853124f33a174f5224d7f3ce23
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF846 DDR2 ZFP1 LRP1 MAPK7	2.24e-05	163	92	5	b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIC1 GRAMD2B RASGEF1B ZFP69 ZNF691	2.66e-05	169	92	5	d18b823836ca6fba79a2d2f10cb9966fa2623af2
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIC1 GRAMD2B RASGEF1B ZFP69 ZNF691	2.66e-05	169	92	5	befb9b1618ea30fbf8983bcc493853da53b809c3
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA ST3GAL5 GRAMD2B LRP1 LARS2	2.98e-05	173	92	5	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA ST3GAL5 GRAMD2B LRP1 LARS2	2.98e-05	173	92	5	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZPBP ZFP1 GRAMD2B ZFP28 SMC5	2.98e-05	173	92	5	de124fb7ded04664d4184bf12f1f201c0784f07c
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	ZNF555 KLHL28 ERMARD ZNF691 ZNF222	3.60e-05	180	92	5	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DDR2 LRP1 PDE7B CNTFR TBX5	4.10e-05	185	92	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HIC1 ZNF569 MYO9A ZNF620 ZFP14	4.10e-05	185	92	5	7925519b855f76444a0b57382ce35d89457b0b14
ToppCell	facs-Spleen-nan-18m-Lymphocytic-CD79a_B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGMN CD38 RASGEF1B SNX9 ZNF691	4.54e-05	189	92	5	159769abb867595f0d20a1835b715b3a96d0a38d
ToppCell	facs-Spleen-nan-18m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGMN CD38 RASGEF1B SNX9 ZNF691	4.65e-05	190	92	5	19c645884950fd261218c42be60f00a2437164a3
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGMN CD38 RASGEF1B SNX9 FAM43A	4.65e-05	190	92	5	ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCell	NS-critical-d_0-4-Epithelial-Basal\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ZNF827 ZFP1 NVL ZNF426 ZNF585B	5.01e-05	193	92	5	1affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DDR2 ZNF81 ZFY ZNF222 ZNF585B	5.14e-05	194	92	5	6be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZNF569 ZFP1 ZNF420 ZNF222 CDC7	5.14e-05	194	92	5	8f4b63b0b9a40765205e4ca6bd94a675a83dbe3d
ToppCell	Bronchial-NucSeq-Stromal-Mesofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPSF4L NOX5 ZNF624 ZNF221 MAPK7	5.39e-05	196	92	5	96e5c6d155273e82ebafa180df8bb589c3e3e54e
ToppCell	Bronchial-NucSeq-Stromal-Mesofibroblastic-Mesothelia\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPSF4L NOX5 ZNF624 ZNF221 MAPK7	5.39e-05	196	92	5	ce13af36fc2932e8125013041742593ff3d07e86
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DDR2 LRP1 PDE7B CNTFR TBX5	5.79e-05	199	92	5	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	DDR2 LRP1 PDE7B CNTFR TBX5	5.93e-05	200	92	5	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DDR2 LRP1 PDE7B CNTFR TBX5	5.93e-05	200	92	5	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	DDR2 LRP1 PDE7B CNTFR TBX5	5.93e-05	200	92	5	a9ff3210127000b3dd9e97136163c98c2b0817d7
Disease	complement factor H-related protein 1 measurement	GALNTL6 FRMPD4 ZBTB41	6.13e-04	56	87	3	EFO_0600054
Disease	Intellectual Disability	KMT2C ZNF142 FRMPD4 ST3GAL5 ASTN1 ZBTB11	2.10e-03	447	87	6	C3714756
Disease	hypertrophic cardiomyopathy	KMT2C ZSCAN2 FADS2B	2.57e-03	92	87	3	EFO_0000538
Disease	diabetes mellitus (implicated_via_orthology)	INSR LRP1	2.67e-03	26	87	2	DOID:9351 (implicated_via_orthology)
Disease	migraine disorder, pulse pressure measurement	HIC1 LRP1	2.67e-03	26	87	2	EFO_0005763, MONDO_0005277

Protein segments in the cluster

Peptide	Gene	Start	Entry
FCLKVIKIATPYMHH	ZNF280D	451	Q6N043
LPKHYDIHRLAKVMQ	EPG5	1426	Q9HCE0
YCHDKKVIHRDIKPE	AURKC	156	Q9UQB9
HCKFLHQYDLTRMPE	CPSF4L	81	A6NMK7
VKRMPCFYLAHELHL	FBXO4	336	Q9UKT5
PCLHYKKMKDNEERE	DGCR8	351	Q8WYQ5
YMKDPVHKHLCIRNE	ASTN1	496	O14525
RCVKYTEIHPEMRHV	CD38	66	P28907
EVCKMLIHMRHPEVY	NVL	276	O15381
QSIMYRHQKRKHTCP	NOX5	601	Q96PH1
KYMHSAQVIHRDLKP	MAPK7	171	Q13164
GKCYHPELQKDMLHC	KMT2C	471	Q8NEZ4
REQIEHHPRVAKYAM	KIF15	501	Q9NS87
QCHKPVHAEYLEKLK	NUDT4B	131	A0A024RBG1
VPLHHRMASAIKCQY	DDR2	336	Q16832
YRNIFSCLPLKHHMV	EPHX4	281	Q8IUS5
HMRIHSGEKPYECQV	HIC1	581	Q14526
PHLMKLHKDNTTCYE	LRP1	1566	Q07954
VTQAMHCYLKEPKLA	PDE7B	181	Q9NP56
HYNPKLCLSEIHKME	INSR	456	P06213
PYELMAKVCHLCVEH	RASGEF1B	76	Q0VAM2
CAKHGLHYVNKPMLR	FADS2B	446	A8MWK0
EKMLKCNEEHPAYLA	OPA1	796	O60313
KHLLNEALKYHFMPE	KLHL28	251	Q9NXS3
KYSHTVNHKPMVCQR	C5orf24	41	Q7Z6I8
KYCFRKNDHVVIAMP	CDC7	121	O00311
TMCPKEHRHLYIDNA	FRMPD4	586	Q14CM0
KDPALKNRCHIRYMH	CNTFR	156	P26992
HFHEKKQIPCVVSML	CASP7	281	P55210
VYRHELKHKAVMLRC	FAM43A	156	Q8N2R8
QTYKKEVCLPRHSMH	C16orf95	56	Q9H693
LYHHMPENRCVLKDL	ERMARD	486	Q5T6L9
KSQKCPMLHHILIFY	GRAMD2B	336	Q96HH9
KLNRKYRSHHDQMIC	SLC13A4	251	Q9UKG4
SLPDIRHANCKHKMY	GALNTL6	121	Q49A17
RHANCKHKMYLERLP	GALNTL6	126	Q49A17
QPKKDLHFLMECNHE	SNX9	481	Q9Y5X1
HFCHDQKMVKHREPF	LARS2	576	Q15031
MHKYQPRLHIVKADE	TBX5	176	Q99593
PGRHQRHLEKMKKCY	RGS22	446	Q8NE09
MRKYQEHEDVPICIH	PTPN12	216	Q05209
PDHMQRLTFKLCHLY	PIWIL4	796	Q7Z3Z4
KMHYVDPDHVKRAQK	ST3GAL5	96	Q9UNP4
HYVHRDIKPDNILMD	CDC42BPA	196	Q5VT25
QKHPKCYRPAMHRLD	BTG4	206	Q9NY30
CLHVPEHFYKETMKN	NLRP9	116	Q7RTR0
MLHQRIHTSEKPYKC	ZNF667	346	Q5HYK9
IVHQRAHMEKKPYEC	ZFP1	256	Q6P2D0
HLRMHTGEKPYKCNE	ZNF624	826	Q9P2J8
HQRVHTGEKPYKCME	ZFP28	691	Q8NHY6
MHKLKHERARDYKCP	ZBTB11	586	O95625
KHMTKFHRDYVPCKI	ZBTB11	931	O95625
ILHMRIHTGEKPYEC	ZNF846	326	Q147U1
MNHERIHTEEKPYAC	ZNF250	411	P15622
VRMHPEDKSYECKLC	ZNF555	471	Q8NEP9
VMHQRAHLGDKPYRC	ZSCAN2	546	Q7Z7L9
HERIHLEEKHYKCPK	ZNF691	161	Q5VV52
ALHMRIHTGEKPYQC	ZNF260	376	Q3ZCT1
HMRNHTAEKPYECKE	ZNF568	436	Q3ZCX4
HKIIHAREKPYKCEE	ZNF723	471	P0DPD5
HMILHSQDKPFKCTY	ZBTB41	481	Q5SVQ8
HQRMHTGEKPYECKE	ZNF620	326	Q6ZNG0
HQKTHMREKPYKCNE	ZNF585B	176	Q52M93
HQKTHMREKPFKCNE	ZNF585A	176	Q6P3V2
MRPDLELQFKCYHHE	ZMIZ2	461	Q8NF64
LHIHQRVHMGEKCYK	ZNF234	191	Q14588
KAYVMLHQKSPHVLC	ZPBP	71	Q9BS86
VCHKFMKTPEQLLEH	ZNF827	1051	Q17R98
HQRMHTGEKPYKCKE	ZNF25	276	P17030
HSMVHIEEKPYKCEQ	ZNF221	356	Q9UK13
VKCLMRKEHCEYNEP	ZNF569	156	Q5MCW4
HMMKHKDIRPYICSE	ZNF366	411	Q8N895
HLRMHTGEKPYECKQ	ZNF57	466	Q68EA5
MQHQRIHTGEKPYKC	ZNF420	351	Q8TAQ5
YLKQHMKTHAPERDV	GTF3A	231	Q92664
HQRIHTREKPYECME	ZFP14	386	Q9HCL3
MAPHCQYSKEKAHER	ZNF782	151	Q6ZMW2
DPSRLKYHMRIHKEE	ZNF142	1491	P52746
QHQRMHTGEKPYECK	ZNF345	331	Q14585
LRIHQRVHMGEKCYK	ZNF224	191	Q9NZL3
PEMHKYHCELKNLRE	SMC5	206	Q8IY18
MAKHHPDLIFCRKQA	PHF5A	1	Q7RTV0
QIHERMHREEKPYEC	ZNF433	466	Q8N7K0
HMRIHTGEKPYECKQ	ZNF426	466	Q9BUY5
AKRLRAQHMKEHPDY	SOX14	61	O95416
HPDMYERAVLRKDHQ	TBK1	181	Q9UHD2
IMHEKTHTREKPYKC	ZNF81	346	P51508
QMHKRIHTGEKPYIC	ZNF81	486	P51508
LKVHCKLHMREKPYN	ZNF222	216	Q9UK12
LCMHQLIHTGEKPYK	ZNF311	346	Q5JNZ3
KHMRIHTGEKPYQCQ	ZFY	561	P08048
CEKIFKQPIHLTEHM	ZFP69	276	Q49AA0
LFNHKRIHMEERPYK	ZNF736	356	B4DX44
YPLHRIKLSMDHVCL	LGMN	416	Q99538
KMYDNHQLGKLEPHI	MYO9A	201	B2RTY4