Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A18 SLC37A1 SLC4A8 SLC7A11 SLC6A3 CLCN3 CLCN4 CLCN7 SLC16A3 SLC34A1 SLC10A5 SLC22A4 SLC4A10 SLC4A9	1.68e-08	296	137	14	GO:0015291
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A18 SLC37A1 ABCA1 SLC4A8 ATP13A2 SLC7A11 SLC6A3 CLCN3 CLCN4 CLCN7 SLC16A3 SLC34A1 SLC10A5 SLC22A4 SLC4A10 TAP2 SLC4A9	3.05e-08	477	137	17	GO:0022804
GeneOntologyMolecularFunction	transporter activity	SLC6A18 SLC37A1 CACNA1B ABCA1 SLC4A8 APOA1 SLC43A3 GRIN2D ATP13A2 SLC7A11 CHRNA7 SLC6A3 CLCN3 CLCN4 CLCN7 SLC16A3 SLC34A1 SLC10A5 SLC22A4 SLC4A10 MTTP SV2C ATP11A SLC51A CHRFAM7A TAP2 SLC4A9 VDAC3	4.35e-08	1289	137	28	GO:0005215
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC6A18 SLC37A1 SLC4A8 SLC6A3 CLCN3 CLCN4 CLCN7 SLC34A1 SLC4A10 SLC4A9	2.93e-07	171	137	10	GO:0015103
GeneOntologyMolecularFunction	sodium,bicarbonate:chloride antiporter activity	SLC4A8 SLC4A10 SLC4A9	3.16e-07	3	137	3	GO:0140892
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA1 NLRP1 MORC2 DDX55 ATP13A2 DDX10 DDX11 DDX18 RECQL4 KIF14 DDX23 DDX3Y ATP11A TAP2 DDX11L8	3.80e-07	441	137	15	GO:0016887
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A18 SLC37A1 CACNA1B ABCA1 SLC4A8 SLC43A3 GRIN2D ATP13A2 SLC7A11 CHRNA7 SLC6A3 CLCN3 CLCN4 CLCN7 SLC16A3 SLC34A1 SLC10A5 SLC22A4 SLC4A10 SV2C SLC51A CHRFAM7A TAP2 SLC4A9 VDAC3	4.17e-07	1180	137	25	GO:0022857
GeneOntologyMolecularFunction	symporter activity	SLC6A18 SLC4A8 SLC6A3 SLC16A3 SLC34A1 SLC10A5 SLC22A4 SLC4A10 SLC4A9	9.47e-07	150	137	9	GO:0015293
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC6A18 SLC4A8 SLC6A3 CLCN3 CLCN4 CLCN7 SLC4A10 SLC4A9 VDAC3	1.00e-06	151	137	9	GO:0008509
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA1 MYO9A NLRP1 MORC2 DDX55 ATP13A2 DDX10 DDX11 DDX18 RECQL4 HLTF KIF14 DDX23 DDX3Y ATP11A TAP2 DDX11L8	1.08e-06	614	137	17	GO:0140657
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DDX55 DDX10 DDX11 DDX18 DDX23 DDX3Y DDX11L8	1.28e-06	80	137	7	GO:0008186
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC6A18 SLC4A8 SLC6A3 SLC34A1 SLC10A5 SLC4A10 SLC4A9	1.40e-06	81	137	7	GO:0015370
GeneOntologyMolecularFunction	helicase activity	DDX55 DDX10 DDX11 DDX18 RECQL4 HLTF DDX23 DDX3Y DDX11L8	1.46e-06	158	137	9	GO:0004386
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A18 SLC4A8 SLC6A3 SLC16A3 SLC34A1 SLC10A5 SLC4A10 SLC4A9	1.65e-06	119	137	8	GO:0015294
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC6A18 SLC4A8 SLC6A3 CLCN3 CLCN4 CLCN7 SLC4A10 SLC4A9	2.40e-06	125	137	8	GO:0015108
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	CLCN3 CLCN4 CLCN7 VDAC3	4.71e-06	17	137	4	GO:0008308
GeneOntologyMolecularFunction	antiporter activity	SLC37A1 SLC4A8 SLC7A11 CLCN3 CLCN4 CLCN7 SLC4A10 SLC4A9	5.02e-06	138	137	8	GO:0015297
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A8 SLC4A10 SLC4A9	6.22e-06	6	137	3	GO:0008510
GeneOntologyMolecularFunction	RNA helicase activity	DDX55 DDX10 DDX18 DDX23 DDX3Y DDX11L8	1.60e-05	78	137	6	GO:0003724
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCA1 ENPP1 NLRP1 RHOT2 MORC2 DDX55 ATP13A2 DDX10 DDX11 DDX18 RECQL4 HLTF KIF14 DDX23 DDX3Y ATP11A TAP2 DDX11L8	1.80e-05	840	137	18	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCA1 ENPP1 NLRP1 RHOT2 MORC2 DDX55 ATP13A2 DDX10 DDX11 DDX18 RECQL4 HLTF KIF14 DDX23 DDX3Y ATP11A TAP2 DDX11L8	1.80e-05	840	137	18	GO:0016818
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC6A18 CACNA1B SLC4A8 GRIN2D ATP13A2 CHRNA7 SLC6A3 CLCN3 CLCN4 CLCN7 SLC16A3 SLC34A1 SLC10A5 SLC4A10 CHRFAM7A SLC4A9 VDAC3	3.12e-05	793	137	17	GO:0015075
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC37A1 SLC4A8 SLC43A3 GRIN2D SLC7A11 SLC16A3 SLC10A5 SLC4A10 SLC51A SLC4A9	3.53e-05	293	137	10	GO:0008514
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCN3 CLCN4 CLCN7	5.01e-05	11	137	3	GO:0005247
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCA1 ENPP1 NLRP1 RHOT2 MORC2 DDX55 ATP13A2 DDX10 DDX11 DDX18 RECQL4 KIF14 DDX23 DDX3Y ATP11A TAP2 DDX11L8	6.28e-05	839	137	17	GO:0016462
GeneOntologyMolecularFunction	solute:inorganic anion antiporter activity	SLC37A1 SLC4A8 SLC4A10 SLC4A9	6.57e-05	32	137	4	GO:0005452
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCA1 NLRP1 RHOT2 MORC2 DDX55 ATP13A2 DDX10 DDX11 DDX18 RECQL4 KIF14 DDX23 DDX3Y ATP11A TAP2 DDX11L8	8.43e-05	775	137	16	GO:0017111
GeneOntologyMolecularFunction	chloride:bicarbonate antiporter activity	SLC4A8 SLC4A10 SLC4A9	8.59e-05	13	137	3	GO:0140900
GeneOntologyMolecularFunction	bicarbonate:monoatomic anion antiporter activity	SLC4A8 SLC4A10 SLC4A9	8.59e-05	13	137	3	GO:0140829
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A8 SLC4A10 SLC4A9	8.59e-05	13	137	3	GO:0140410
GeneOntologyMolecularFunction	melanocyte-stimulating hormone receptor activity	MC1R MC3R	1.40e-04	3	137	2	GO:0004980
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC6A18 SLC4A8 SLC6A3 SLC34A1 SLC10A5 SLC4A10 SLC4A9	1.81e-04	171	137	7	GO:0015081
GeneOntologyMolecularFunction	aldehyde dehydrogenase [NAD(P)+] activity	ALDH1L1 ADH4 ALDH9A1	2.00e-04	17	137	3	GO:0004030
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC6A18 SLC37A1 CACNA1B SLC4A8 GRIN2D CHRNA7 SLC6A3 CLCN3 CLCN4 CLCN7 SLC16A3 SLC34A1 SLC10A5 SLC4A10 SLC4A9	2.25e-04	758	137	15	GO:0015318
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC6A18 SLC4A8 ATP13A2 SLC6A3 SLC16A3 SLC34A1 SLC10A5 SLC4A10 SLC4A9	2.37e-04	301	137	9	GO:0022853
GeneOntologyMolecularFunction	triplex DNA binding	DDX11 DDX11L8	2.78e-04	4	137	2	GO:0045142
GeneOntologyMolecularFunction	lipid transporter activity	ABCA1 APOA1 SLC43A3 SLC10A5 MTTP ATP11A SLC51A	4.14e-04	196	137	7	GO:0005319
GeneOntologyMolecularFunction	cholesterol transfer activity	ABCA1 APOA1 MTTP	5.75e-04	24	137	3	GO:0120020
GeneOntologyMolecularFunction	sterol transfer activity	ABCA1 APOA1 MTTP	6.51e-04	25	137	3	GO:0120015
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A18 CACNA1B SLC4A8 GRIN2D ATP13A2 CHRNA7 SLC6A3 SLC16A3 SLC34A1 SLC10A5 SLC4A10 CHRFAM7A SLC4A9	6.61e-04	664	137	13	GO:0008324
GeneOntologyMolecularFunction	melanocortin receptor activity	MC1R MC3R	6.88e-04	6	137	2	GO:0004977
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC4A8 SLC4A10 SLC4A9	1.35e-03	32	137	3	GO:0015106
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLC6A3 SLC16A3 SLC10A5 SLC51A	1.37e-03	70	137	4	GO:1901618
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A18 CACNA1B SLC4A8 GRIN2D CHRNA7 SLC6A3 SLC34A1 SLC10A5 SLC4A10 SLC4A9	1.40e-03	465	137	10	GO:0046873
GeneOntologyMolecularFunction	peptide binding	CACNA1B MC3R APOA1 NUP214 CHRNA7 PREP CHRFAM7A TAP2	1.60e-03	318	137	8	GO:0042277
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1B GRIN2D CLCN3 CLCN4 CLCN7 VDAC3	1.62e-03	182	137	6	GO:0005244
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ABCA1 ATP11A	1.63e-03	9	137	2	GO:0090556
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1B GRIN2D CLCN3 CLCN4 CLCN7 VDAC3	1.71e-03	184	137	6	GO:0022832
GeneOntologyMolecularFunction	gated channel activity	CACNA1B GRIN2D CHRNA7 CLCN3 CLCN4 CLCN7 CHRFAM7A VDAC3	2.18e-03	334	137	8	GO:0022836
GeneOntologyMolecularFunction	5'-3' DNA helicase activity	DDX11 DDX11L8	2.47e-03	11	137	2	GO:0043139
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC43A3 GRIN2D SLC7A11 SLC16A3 SLC10A5 SLC51A	3.08e-03	207	137	6	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC43A3 GRIN2D SLC7A11 SLC16A3 SLC10A5 SLC51A	3.16e-03	208	137	6	GO:0005342
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	SLC4A8 SLC4A10 SLC4A9	3.19e-03	43	137	3	GO:0140828
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	SLC43A3 SLC16A3 SLC10A5 SLC51A	3.44e-03	90	137	4	GO:0008028
GeneOntologyMolecularFunction	pseudouridine synthase activity	RPUSD3 PUS7L	3.47e-03	13	137	2	GO:0009982
GeneOntologyMolecularFunction	acetylcholine binding	CHRNA7 CHRFAM7A	3.47e-03	13	137	2	GO:0042166
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC6A18 CACNA1B SLC4A8 GRIN2D CHRNA7 SLC6A3 SLC16A3 SLC34A1 SLC10A5 SLC4A10 SLC4A9	4.00e-03	627	137	11	GO:0022890
GeneOntologyMolecularFunction	G-quadruplex DNA binding	DDX11 DDX11L8	4.03e-03	14	137	2	GO:0051880
GeneOntologyMolecularFunction	4 iron, 4 sulfur cluster binding	DDX11 CIAPIN1 DDX11L8	4.11e-03	47	137	3	GO:0051539
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	ALDH1L1 ADH4 ALDH9A1	4.36e-03	48	137	3	GO:0016620
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA1 ATP13A2 TAP2	4.62e-03	49	137	3	GO:0140359
GeneOntologyMolecularFunction	aldehyde dehydrogenase (NAD+) activity	ALDH1L1 ALDH9A1	4.63e-03	15	137	2	GO:0004029
GeneOntologyMolecularFunction	high-density lipoprotein particle binding	ABCA1 APOA1	4.63e-03	15	137	2	GO:0008035
GeneOntologyMolecularFunction	chloride channel regulator activity	CHRNA7 CHRFAM7A	4.63e-03	15	137	2	GO:0017081
GeneOntologyMolecularFunction	adenylate cyclase binding	CHRNA7 CHRFAM7A	5.27e-03	16	137	2	GO:0008179
GeneOntologyMolecularFunction	floppase activity	ABCA1 ATP11A	5.27e-03	16	137	2	GO:0140328
GeneOntologyMolecularFunction	amyloid-beta binding	CACNA1B APOA1 CHRNA7 CHRFAM7A	5.36e-03	102	137	4	GO:0001540
GeneOntologyMolecularFunction	monoatomic anion channel activity	CLCN3 CLCN4 CLCN7 VDAC3	5.55e-03	103	137	4	GO:0005253
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A18 GRIN2D SLC7A11 SLC22A4	5.94e-03	105	137	4	GO:0015171
GeneOntologyMolecularFunction	sodium:chloride symporter activity	SLC6A18 SLC6A3	5.94e-03	17	137	2	GO:0015378
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA7 CHRFAM7A	5.94e-03	17	137	2	GO:0022848
GeneOntologyMolecularFunction	ATPase binding	ABCA1 SRC CHRNA7 CHRFAM7A	6.56e-03	108	137	4	GO:0051117
GeneOntologyMolecularFunction	DNA replication origin binding	DDX11 DDX11L8	6.65e-03	18	137	2	GO:0003688
GeneOntologyMolecularFunction	toxic substance binding	CHRNA7 CHRFAM7A	6.65e-03	18	137	2	GO:0015643
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors	ALDH1L1 ADH4 ALDH9A1	6.72e-03	56	137	3	GO:0016903
GeneOntologyMolecularFunction	lipid transfer activity	ABCA1 APOA1 MTTP	7.06e-03	57	137	3	GO:0120013
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GRIN2D CHRNA7 CHRFAM7A	7.06e-03	57	137	3	GO:1904315
GeneOntologyMolecularFunction	secondary active monocarboxylate transmembrane transporter activity	SLC16A3 SLC10A5	7.40e-03	19	137	2	GO:0015355
GeneOntologyMolecularFunction	monoatomic anion:sodium symporter activity	SLC6A18 SLC6A3	7.40e-03	19	137	2	GO:0015373
GeneOntologyBiologicalProcess	inorganic anion transport	SLC37A1 SLC4A8 ENPP1 CLCN3 CLCN4 CLCN7 SLC34A1 SLC4A10 SLC4A9	2.58e-06	180	133	9	GO:0015698
GeneOntologyBiologicalProcess	positive regulation of CoA-transferase activity	APOA1 CHRNA7 CHRFAM7A	2.14e-05	9	133	3	GO:1905920
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	SLC37A1 SLC4A8 CLCN3 CLCN4 CLCN7 SLC34A1 SLC4A9	2.63e-05	134	133	7	GO:0098661
GeneOntologyBiologicalProcess	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	CHRNA7 CHRFAM7A	4.13e-05	2	133	2	GO:0001988
GeneOntologyBiologicalProcess	regulation of CoA-transferase activity	APOA1 CHRNA7 CHRFAM7A	4.16e-05	11	133	3	GO:1905918
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	SLC4A8 CLCN3 CLCN4 CLCN7 SLC4A10 SLC4A9 VDAC3	6.14e-05	153	133	7	GO:0098656
GeneOntologyBiologicalProcess	sodium ion transport	SLC6A18 SLC4A8 PON3 SLC6A3 SLC34A1 SLC10A5 SLC22A4 SLC4A10 SLC4A9	7.53e-05	275	133	9	GO:0006814
GeneOntologyBiologicalProcess	norepinephrine transport	P2RY12 CHRNA7 SLC6A3 CHRFAM7A	1.03e-04	38	133	4	GO:0015874
GeneOntologyBiologicalProcess	organic hydroxy compound transport	ABCA1 P2RY12 APOA1 CHRNA7 SLC6A3 SLC16A3 SLC10A5 MTTP SLC51A CHRFAM7A	1.12e-04	358	133	10	GO:0015850
GeneOntologyBiologicalProcess	baroreceptor response to decreased systemic arterial blood pressure	CHRNA7 CHRFAM7A	1.23e-04	3	133	2	GO:0001982
GeneOntologyBiologicalProcess	chloride transport	SLC4A8 CLCN3 CLCN4 CLCN7 SLC4A10 SLC4A9	1.83e-04	128	133	6	GO:0006821
GeneOntologyBiologicalProcess	monoatomic anion transport	SLC4A8 CLCN3 CLCN4 CLCN7 SLC4A10 SLC4A9 VDAC3	1.87e-04	183	133	7	GO:0006820
GeneOntologyCellularComponent	basal plasma membrane	EPS15 ABCA1 SLC4A8 P2RY12 ENPP1 SLC43A3 SLC16A3 SLC34A1 SLC22A4 SLC4A10 MTTP SLC51A SLC4A9	3.98e-07	354	132	13	GO:0009925
GeneOntologyCellularComponent	basal part of cell	EPS15 ABCA1 SLC4A8 P2RY12 ENPP1 SLC43A3 SLC16A3 SLC34A1 SLC22A4 SLC4A10 MTTP SLC51A SLC4A9	8.33e-07	378	132	13	GO:0045178
GeneOntologyCellularComponent	apical part of cell	SLC6A18 EPS15 SLC4A8 EPB41L4B DUOX2 SLC7A11 CHRNA7 CLCN3 SLC16A3 SLC34A1 SLC22A4 SLC4A10 CHRFAM7A SLC4A9	2.33e-05	592	132	14	GO:0045177
GeneOntologyCellularComponent	basolateral plasma membrane	ABCA1 SLC4A8 ENPP1 SLC43A3 SLC16A3 SLC34A1 SLC4A10 MTTP SLC51A SLC4A9	3.69e-05	320	132	10	GO:0016323
GeneOntologyCellularComponent	distal axon	CACNA1B SLC4A8 MYO9A PTBP2 ITSN1 SRC CHRNA7 SLC6A3 CLCN3 SLC4A10 CHRFAM7A	1.01e-04	435	132	11	GO:0150034
GeneOntologyCellularComponent	spine apparatus membrane	CHRNA7 CHRFAM7A	1.18e-04	3	132	2	GO:0098897
GeneOntologyCellularComponent	apical plasma membrane	SLC6A18 EPS15 SLC4A8 DUOX2 CHRNA7 CLCN3 SLC16A3 SLC34A1 SLC22A4 SLC4A10 CHRFAM7A	2.69e-04	487	132	11	GO:0016324
GeneOntologyCellularComponent	plasma membrane raft	P2RY12 SRC CHRNA7 SLC6A3 MYOF CHRFAM7A	3.45e-04	147	132	6	GO:0044853
GeneOntologyCellularComponent	cell projection membrane	SLC6A18 EPS15 P2RY12 SRC SLC7A11 CHRNA7 CLCN3 SLC34A1 MTTP CHRFAM7A	4.17e-04	431	132	10	GO:0031253
GeneOntologyCellularComponent	apical dendrite	ENPP1 ITSN1 SLC4A10	1.07e-03	32	132	3	GO:0097440
GeneOntologyCellularComponent	spine apparatus	CHRNA7 CHRFAM7A	1.38e-03	9	132	2	GO:0097444
GeneOntologyCellularComponent	axon	IGSF8 CACNA1B SLC4A8 MYO9A PTBP2 ITSN1 SERPINF1 SRC DSCAML1 CHRNA7 SLC6A3 CLCN3 SLC4A10 CHRFAM7A	1.52e-03	891	132	14	GO:0030424
GeneOntologyCellularComponent	Ctf18 RFC-like complex	DDX11 DDX11L8	1.72e-03	10	132	2	GO:0031390
GeneOntologyCellularComponent	basal dendrite	ENPP1 SLC4A10	1.72e-03	10	132	2	GO:0097441
GeneOntologyCellularComponent	brush border membrane	SLC6A18 SLC7A11 SLC34A1 MTTP	1.90e-03	83	132	4	GO:0031526
GeneOntologyCellularComponent	membrane raft	TRAF2 ABCA1 P2RY12 SRC CHRNA7 SLC6A3 MYOF CHRFAM7A	2.14e-03	362	132	8	GO:0045121
GeneOntologyCellularComponent	axon terminus	CACNA1B SLC4A8 ITSN1 SLC6A3 CLCN3 SLC4A10	2.20e-03	210	132	6	GO:0043679
GeneOntologyCellularComponent	membrane microdomain	TRAF2 ABCA1 P2RY12 SRC CHRNA7 SLC6A3 MYOF CHRFAM7A	2.22e-03	364	132	8	GO:0098857
MousePheno	abnormal cerebral cortex pyramidal cell morphology	CHRNA7 CLCN3 CLCN7 KIF14 CHRFAM7A	3.55e-06	32	104	5	MP:0009969
MousePheno	airway basal cell hyperplasia	CHRNA7 CHRFAM7A	5.48e-05	2	104	2	MP:0011115
MousePheno	abnormal airway basal cell differentiation	CHRNA7 CHRFAM7A	5.48e-05	2	104	2	MP:0011114
MousePheno	abnormal airway basal cell morphology	CHRNA7 CHRFAM7A	5.48e-05	2	104	2	MP:0011113
Domain	DUF4217	DDX55 DDX10 DDX18	1.40e-06	4	133	3	PF13959
Domain	DUF4217	DDX55 DDX10 DDX18	1.40e-06	4	133	3	SM01178
Domain	DUF4217	DDX55 DDX10 DDX18	1.40e-06	4	133	3	IPR025313
Domain	DEAD_ATP_HELICASE	DDX55 DDX10 DDX18 DDX23 DDX3Y	2.49e-06	31	133	5	PS00039
Domain	RNA-helicase_DEAD-box_CS	DDX55 DDX10 DDX18 DDX23 DDX3Y	3.43e-06	33	133	5	IPR000629
Domain	Na/HCO3_transpt	SLC4A8 SLC4A10 SLC4A9	3.49e-06	5	133	3	IPR003024
Domain	Q_MOTIF	DDX55 DDX10 DDX18 DDX23 DDX3Y	6.16e-06	37	133	5	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX55 DDX10 DDX18 DDX23 DDX3Y	6.16e-06	37	133	5	IPR014014
Domain	Helicase_C	DDX55 DDX10 DDX18 RECQL4 HLTF DDX23 DDX3Y	1.14e-05	107	133	7	PF00271
Domain	HELICc	DDX55 DDX10 DDX18 RECQL4 HLTF DDX23 DDX3Y	1.14e-05	107	133	7	SM00490
Domain	Helicase_C	DDX55 DDX10 DDX18 RECQL4 HLTF DDX23 DDX3Y	1.22e-05	108	133	7	IPR001650
Domain	HELICASE_CTER	DDX55 DDX10 DDX18 RECQL4 HLTF DDX23 DDX3Y	1.29e-05	109	133	7	PS51194
Domain	HELICASE_ATP_BIND_1	DDX55 DDX10 DDX18 RECQL4 HLTF DDX23 DDX3Y	1.29e-05	109	133	7	PS51192
Domain	DEXDc	DDX55 DDX10 DDX18 RECQL4 HLTF DDX23 DDX3Y	1.29e-05	109	133	7	SM00487
Domain	DEAD/DEAH_box_helicase_dom	DDX55 DDX10 DDX18 RECQL4 DDX23 DDX3Y	1.34e-05	73	133	6	IPR011545
Domain	DEAD	DDX55 DDX10 DDX18 RECQL4 DDX23 DDX3Y	1.34e-05	73	133	6	PF00270
Domain	Helicase_ATP-bd	DDX55 DDX10 DDX18 RECQL4 HLTF DDX23 DDX3Y	1.37e-05	110	133	7	IPR014001
Domain	Cl-channel_core	CLCN3 CLCN4 CLCN7	2.87e-05	9	133	3	IPR014743
Domain	-	SLC4A8 SLC4A10 SLC4A9	2.87e-05	9	133	3	3.40.1100.10
Domain	-	CLCN3 CLCN4 CLCN7	2.87e-05	9	133	3	1.10.3080.10
Domain	Voltage_CLC	CLCN3 CLCN4 CLCN7	2.87e-05	9	133	3	PF00654
Domain	Cl-channel_volt-gated	CLCN3 CLCN4 CLCN7	2.87e-05	9	133	3	IPR001807
Domain	Band3_cytoplasmic_dom	SLC4A8 SLC4A10 SLC4A9	2.87e-05	9	133	3	IPR013769
Domain	Band_3_cyto	SLC4A8 SLC4A10 SLC4A9	2.87e-05	9	133	3	PF07565
Domain	DUF4939	RTL8B RTL8A RTL8C	4.08e-05	10	133	3	IPR032549
Domain	PTrfase/Anion_transptr	SLC4A8 SLC4A10 SLC4A9	4.08e-05	10	133	3	IPR016152
Domain	HCO3_transpt_euk	SLC4A8 SLC4A10 SLC4A9	4.08e-05	10	133	3	IPR003020
Domain	DUF4939	RTL8B RTL8A RTL8C	4.08e-05	10	133	3	PF16297
Domain	HCO3_cotransp	SLC4A8 SLC4A10 SLC4A9	4.08e-05	10	133	3	PF00955
Domain	HCO3_transpt_C	SLC4A8 SLC4A10 SLC4A9	4.08e-05	10	133	3	IPR011531
Domain	LDOC1-rel	RTL8B RTL8A RTL8C	5.59e-05	11	133	3	IPR032567
Domain	CBS	CLCN3 CLCN4 CLCN7	1.85e-04	16	133	3	SM00116
Domain	MFS_1	SLC37A1 SLC43A3 SLC16A3 SLC22A4 SV2C	2.22e-04	77	133	5	PF07690
Domain	MFS	SLC37A1 SLC43A3 SLC16A3 SLC22A4 SV2C	2.22e-04	77	133	5	IPR011701
Domain	CBS_dom	CLCN3 CLCN4 CLCN7	3.68e-04	20	133	3	IPR000644
Domain	CBS	CLCN3 CLCN4 CLCN7	3.68e-04	20	133	3	PF00571
Domain	CBS	CLCN3 CLCN4 CLCN7	3.68e-04	20	133	3	PS51371
Domain	-	AASDH ALDH1L1	4.96e-04	5	133	2	1.10.1200.10
Domain	HnRNP-L/PTB	PTBP3 PTBP2	4.96e-04	5	133	2	IPR006536
Domain	PP-binding	AASDH ALDH1L1	4.96e-04	5	133	2	PF00550
Domain	ACP_DOMAIN	AASDH ALDH1L1	4.96e-04	5	133	2	PS50075
Domain	Melcrt_ACTH_rcpt	MC1R MC3R	7.41e-04	6	133	2	IPR001671
Domain	PP-bd_ACP	AASDH ALDH1L1	7.41e-04	6	133	2	IPR009081
Domain	ANION_EXCHANGER_2	SLC4A8 SLC4A10	1.03e-03	7	133	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A8 SLC4A10	1.03e-03	7	133	2	PS00219
Domain	P-loop_NTPase	ABCA1 MYO9A NLRP1 RHOT2 DDX55 DDX10 DDX11 DDX18 RECQL4 HLTF KIF14 DDX23 DDX3Y TAP2 HYDIN	1.05e-03	848	133	15	IPR027417
Domain	EF-hand_4	EPS15 ITSN1	2.18e-03	10	133	2	PF12763
Domain	-	ABCA1 NLRP1 RHOT2 DDX55 DDX10 DDX11 DDX18 RECQL4 HLTF DDX23 DDX3Y TAP2 HYDIN	2.59e-03	746	133	13	3.40.50.300
Domain	EH	EPS15 ITSN1	2.65e-03	11	133	2	PS50031
Domain	EH	EPS15 ITSN1	2.65e-03	11	133	2	SM00027
Domain	EH_dom	EPS15 ITSN1	2.65e-03	11	133	2	IPR000261
Domain	MFS_dom	SLC37A1 SLC43A3 SLC16A3 SLC22A4 SV2C	2.72e-03	134	133	5	IPR020846
Domain	PsdUridine_synth_cat_dom	RPUSD3 PUS7L	3.73e-03	13	133	2	IPR020103
Domain	Methyltransf_11	COQ3 CIAPIN1	5.66e-03	16	133	2	IPR013216
Domain	Methyltransf_11	COQ3 CIAPIN1	5.66e-03	16	133	2	PF08241
Domain	Ald_DH_CS_GLU	ALDH1L1 ALDH9A1	5.66e-03	16	133	2	IPR029510
Domain	Ald_DH_CS_CYS	ALDH1L1 ALDH9A1	6.38e-03	17	133	2	IPR016160
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A18 ABCA1 SLC4A8 APOA1 ATP13A2 SLC7A11 SLC6A3 CLCN3 CLCN4 CLCN7 SLC16A3 SLC34A1 SLC22A4 SLC4A10 MTTP ATP11A AKAP1 SLC4A9 VDAC3	9.83e-07	736	101	19	M27287
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A18 ABCA1 SLC4A8 APOA1 ATP13A2 SLC7A11 SLC6A3 CLCN4 CLCN7 SLC16A3 SLC34A1 SLC22A4 SLC4A10 MTTP ATP11A SLC4A9	2.54e-05	681	101	16	MM14985
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A8 SLC4A10 SLC4A9	4.13e-05	10	101	3	M27335
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A8 SLC4A10 SLC4A9	4.13e-05	10	101	3	MM15073
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A18 SLC4A8 SLC7A11 SLC6A3 SLC16A3 SLC34A1 SLC22A4 SLC4A10 SLC4A9	5.19e-05	238	101	9	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A18 SLC4A8 SLC7A11 SLC6A3 SLC16A3 SLC34A1 SLC22A4 SLC4A10 SLC4A9	7.36e-05	249	101	9	M5988
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC6A18 SLC4A8 SLC7A11 SLC34A1 SLC4A10 SLC4A9	1.24e-04	108	101	6	M823
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC6A18 SLC4A8 SLC7A11 SLC34A1 SLC4A10 SLC4A9	1.30e-04	109	101	6	MM15074
Pathway	WP_METABOLIC_PATHWAY_OF_LDL_HDL_AND_TG_INCLUDING_DISEASES	ABCA1 APOA1 MTTP	2.26e-04	17	101	3	M39747
Pathway	REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY	ABCA1 APOA1 MTTP	2.26e-04	17	101	3	MM15561
Pathway	REACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS	SLC6A18 ABCA1 APOA1 NUP214 NUP205 SLC6A3 SLC34A1	2.79e-04	177	101	7	M27476
Pathway	REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY	ABCA1 APOA1 MTTP	3.18e-04	19	101	3	M27841
Pathway	WP_STATIN_PATHWAY	ABCA1 APOA1 MTTP	3.18e-04	19	101	3	MM15868
Pubmed	Defining the membrane proteome of NK cells.	IGSF8 SLC37A1 EPS15 ICAM2 RHOT2 DDX55 NUP205 SCCPDH CLCN3 CLCN7 PREP DDX18 RECQL4 CEP41 HLTF KIF14 DDX3Y ATP11A AKAP1 TAP2	3.55e-08	1168	137	20	19946888
Pubmed	A low-copy repeat in Xq26 represents a novel putatively prenylated protein gene (CXX1) and its pseudogenes (DXS9914, DXS9915, and DXS9916).	RTL8B RTL8A RTL8C	5.98e-08	3	137	3	9403077
Pubmed	Sperm epidermal growth factor receptor (EGFR) mediates α7 acetylcholine receptor (AChR) activation to promote fertilization.	SRC CHRNA7 CHRFAM7A	2.38e-07	4	137	3	22577141
Pubmed	RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control.	RTL8B RTL8A RTL8C	1.19e-06	6	137	3	35247097
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	TRAF2 GPATCH1 VIRMA SLC16A3 ATP11A PRMT7	3.50e-06	103	137	6	29539633
Pubmed	Changing expression of chloride channels during preimplantation mouse development.	CLCN3 CLCN4 CLCN7	4.94e-06	9	137	3	23115349
Pubmed	A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes.	RTL8B RTL8A RTL8C	9.64e-06	11	137	3	16093683
Pubmed	Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals.	RTL8B RTL8A RTL8C	9.64e-06	11	137	3	15716091
Pubmed	Ion channel expression in the developing enteric nervous system.	CACNA1B CLCN3 CLCN4 CLCN7	1.38e-05	37	137	4	25798587
Pubmed	Formation of two intramolecular disulfide bonds is necessary for ApoA-I-dependent cholesterol efflux mediated by ABCA1.	ABCA1 APOA1	1.54e-05	2	137	2	19258317
Pubmed	Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	38070724
Pubmed	Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis.	MC1R MC3R	1.54e-05	2	137	2	32029712
Pubmed	Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	34453977
Pubmed	Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	26999808
Pubmed	Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	27129924
Pubmed	Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	23521765
Pubmed	Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	28258105
Pubmed	The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	19344760
Pubmed	First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation.	ABCA1 APOA1	1.54e-05	2	137	2	31945064
Pubmed	Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	29114104
Pubmed	Pigment epithelium-derived factor (PEDF) interacts with transportin SR2, and active nuclear import is facilitated by a novel nuclear localization motif.	SERPINF1 TNPO3	1.54e-05	2	137	2	22028839
Pubmed	Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	33995108
Pubmed	E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	32552811
Pubmed	Niacin increases HDL biogenesis by enhancing DR4-dependent transcription of ABCA1 and lipidation of apolipoprotein A-I in HepG2 cells.	ABCA1 APOA1	1.54e-05	2	137	2	22389325
Pubmed	Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	24836856
Pubmed	Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	15948184
Pubmed	Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	35678315
Pubmed	Intraperitoneal pyrophosphate treatment reduces renal calcifications in Npt2a null mice.	ENPP1 SLC34A1	1.54e-05	2	137	2	28704395
Pubmed	Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	12628457
Pubmed	Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	25157794
Pubmed	Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	31202708
Pubmed	Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	22246862
Pubmed	Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	27471776
Pubmed	Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	22688057
Pubmed	K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.	SLC4A8 SLC4A10	1.54e-05	2	137	2	38674160
Pubmed	Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	32028688
Pubmed	Myocardial infarction in a 36-year-old man with combined ABCA1 and APOA-1 deficiency.	ABCA1 APOA1	1.54e-05	2	137	2	26073400
Pubmed	Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	30429582
Pubmed	A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	21501254
Pubmed	Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	21368056
Pubmed	Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	1400473
Pubmed	Mutations in APOA-I and ABCA1 in Norwegians with low levels of HDL cholesterol.	ABCA1 APOA1	1.54e-05	2	137	2	20800056
Pubmed	Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I.	ABCA1 APOA1	1.54e-05	2	137	2	12869555
Pubmed	Effects of apolipoprotein A-I on ATP-binding cassette transporter A1-mediated efflux of macrophage phospholipid and cholesterol: formation of nascent high density lipoprotein particles.	ABCA1 APOA1	1.54e-05	2	137	2	12928428
Pubmed	KIAA1429 protects hepatocellular carcinoma cells from ferroptotic cell death with a m6 A-dependent posttranscriptional modification of SLC7A11.	SLC7A11 VIRMA	1.54e-05	2	137	2	37830241
Pubmed	Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	26937017
Pubmed	Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I.	ABCA1 APOA1	1.54e-05	2	137	2	16418537
Pubmed	Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux.	ABCA1 APOA1	1.54e-05	2	137	2	12050168
Pubmed	Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	36603528
Pubmed	Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	26650489
Pubmed	Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	22848433
Pubmed	Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	16650968
Pubmed	Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	35413868
Pubmed	Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	24462939
Pubmed	Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	29261717
Pubmed	Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	18199426
Pubmed	Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	22490926
Pubmed	Preferential association with ClC-3 permits sorting of ClC-4 into endosomal compartments.	CLCN3 CLCN4	1.54e-05	2	137	2	28972156
Pubmed	Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	23270857
Pubmed	Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	18077004
Pubmed	The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease.	ABCA1 APOA1	1.54e-05	2	137	2	14747463
Pubmed	Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	19462340
Pubmed	Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	16923147
Pubmed	NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	11790782
Pubmed	ABCA1 (ATP-Binding Cassette Transporter A1) Mediates ApoA-I (Apolipoprotein A-I) and ApoA-I Mimetic Peptide Mobilization of Extracellular Cholesterol Microdomains Deposited by Macrophages.	ABCA1 APOA1	1.54e-05	2	137	2	27758769
Pubmed	Novel Insights into Concepts and Directionality of Maternal⁻Fetal Cholesterol Transfer across the Human Placenta.	ABCA1 APOA1	1.54e-05	2	137	2	30096856
Pubmed	Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	37746145
Pubmed	A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	19631623
Pubmed	Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	15770102
Pubmed	Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	24326163
Pubmed	The lipidation by hepatocytes of human apolipoprotein A-I occurs by both ABCA1-dependent and -independent pathways.	ABCA1 APOA1	1.54e-05	2	137	2	12547832
Pubmed	Microexon-based regulation of ITSN1 and Src SH3 domains specificity relies on introduction of charged amino acids into the interaction interface.	ITSN1 SRC	1.54e-05	2	137	2	20659428
Pubmed	Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	23811428
Pubmed	Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	20720594
Pubmed	Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	17019565
Pubmed	Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	19100751
Pubmed	Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	35883638
Pubmed	Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	19368846
Pubmed	Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	15009674
Pubmed	Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter.	ABCA1 APOA1	1.54e-05	2	137	2	14701824
Pubmed	Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.	ABCA1 APOA1	1.54e-05	2	137	2	14967052
Pubmed	Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	38253622
Pubmed	ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-I.	ABCA1 APOA1	1.54e-05	2	137	2	14703508
Pubmed	The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	34514543
Pubmed	α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	22183893
Pubmed	Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	9364063
Pubmed	Evidence suggesting that the mouse sperm acrosome reaction initiated by the zona pellucida involves an alpha7 nicotinic acetylcholine receptor.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	12606407
Pubmed	ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes.	ABCA1 APOA1	1.54e-05	2	137	2	14993246
Pubmed	Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	22300029
Pubmed	GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	32018068
Pubmed	CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	26206074
Pubmed	Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	24349346
Pubmed	The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	21143250
Pubmed	Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	16319313
Pubmed	Impaired synaptic plasticity in the visual cortex of mice lacking α7-nicotinic receptor subunit.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	25797465
Pubmed	Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	29197398
Pubmed	Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	38178134
Pubmed	In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	23325242
Pubmed	Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors.	CHRNA7 CHRFAM7A	1.54e-05	2	137	2	22649244
Pubmed	Increased prevalence of clinical and subclinical atherosclerosis in patients with damaging mutations in ABCA1 or APOA1.	ABCA1 APOA1	1.54e-05	2	137	2	29150341
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	CACNA1B TRAF2 LCN8 NUP214 KYAT1 MIGA2 PNPLA7	5.85e-05	325	137	7	chr9q34
Cytoband	Ensembl 112 genes in cytogenetic band chr4q23	C4orf54 ADH4 MTTP	1.88e-04	37	137	3	chr4q23
Cytoband	9q34.11	OR1J4 KYAT1 MIGA2	5.46e-04	53	137	3	9q34.11
GeneFamily	Solute carriers	SLC6A18 SLC37A1 SLC4A8 SLC43A3 SLC7A11 SLC35F5 SLC6A3 SLC16A3 SLC34A1 SLC10A5 SLC22A4 SLC4A10 SLC51A SLC4A9	2.42e-08	395	97	14	752
GeneFamily	DEAD-box helicases	DDX55 DDX10 DDX11 DDX18 DDX23 DDX3Y	9.15e-08	42	97	6	499
GeneFamily	Chloride voltage-gated channels	CLCN3 CLCN4 CLCN7	1.75e-05	10	97	3	302
GeneFamily	Melanocortin receptors	MC1R MC3R	2.82e-04	5	97	2	236
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC37A1 MYO9A NBEAL1 HEATR5A DSCAML1 MYOF SYTL5 ATP11A IFT80	1.19e-08	199	137	9	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYO9A NBEAL1 HEATR5A DSCAML1 MYOF SYTL5 ATP11A IFT80	2.03e-07	200	137	8	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1B MS4A18 DUOX2 MDGA2 PKHD1L1 SLC6A3 HYDIN	7.16e-07	162	137	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A18 ABHD3 PTER KYAT1 SLC34A1 ATP11A SLC51A	1.03e-06	171	137	7	48fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCell	droplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A18 ABHD3 PTER KYAT1 SLC34A1 ATP11A SLC51A	1.03e-06	171	137	7	05fcc72df50a380a913821b5781d9621df37d328
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ENPP1 PTCHD4 DSCAML1 SLC35F5 SLC6A3 HYDIN	1.50e-06	181	137	7	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLC37A1 HEATR5A DSCAML1 MYOF SYTL5 ATP11A IFT80	2.82e-06	199	137	7	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-Like-AT1-AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC37A1 EPB41L4B ALDH1L1 GRIN2D F2RL1 SYTL5	2.86e-06	128	137	6	082b3dc312b033c9b21cf73499009a1dc049ee2b
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC37A1 MYO9A HEATR5A MYOF SYTL5 ATP11A IFT80	2.91e-06	200	137	7	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINF1 ALDH1L1 PTER KYAT1 MTTP PNPLA7	1.23e-05	165	137	6	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A18 ABHD3 PTER KYAT1 SLC34A1 ATP11A	1.27e-05	166	137	6	8ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1B ENPP1 SERPINF1 CLCN4 LACC1 CHRFAM7A	1.27e-05	166	137	6	b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1B ENPP1 SERPINF1 CLCN4 LACC1 CHRFAM7A	1.31e-05	167	137	6	e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC37A1 COQ3 NUP205 RPUSD3 CEP41 PUS7L	1.77e-05	176	137	6	91ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A DSCAML1 SLC35F5 SLC6A3 GADL1 HYDIN	2.07e-05	181	137	6	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	wk_08-11-Epithelial-PNS-PCP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CACNA1B SLC4A8 MC1R FRY SV2C CHRFAM7A	2.27e-05	184	137	6	eac2a9089913f33a961ba11519b53645790f2056
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A DSCAML1 SLC35F5 MYOF ATP11A HYDIN	3.06e-05	194	137	6	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLC37A1 HEATR5A MYOF LTA4H ATP11A IFT80	3.33e-05	197	137	6	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	NBEAL1 HEATR5A MYOF SYTL5 ATP11A IFT80	3.43e-05	198	137	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLC37A1 NBEAL1 HEATR5A DSCAML1 MYOF SYTL5	3.43e-05	198	137	6	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	TCGA-Stomach-Primary_Tumor\|TCGA-Stomach / Sample_Type by Project: Shred V9	TRAF2 ZNF267 DDX18 RECQL4 KIF14 ATP11A	3.53e-05	199	137	6	38f1f612b29feb868322999ceeda78e52447ec4f
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma\|TCGA-Stomach / Sample_Type by Project: Shred V9	TRAF2 ZNF267 DDX18 RECQL4 KIF14 ATP11A	3.53e-05	199	137	6	b10698aee2e6c17bc559eb4f723024141f914b90
ToppCell	LPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLC37A1 P2RY12 SRC PKHD1L1 KYAT1 SLC51A	3.63e-05	200	137	6	326cae37cacd94b423a6ac8873ea56c5abaf0a0b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_9\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1B VIRMA MYOF RTL8A RTL8C	3.79e-05	122	137	5	489a01c71882be5a6d71a19d06574698988c20f6
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_9\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1B VIRMA MYOF RTL8A RTL8C	3.79e-05	122	137	5	7dabf8b4c34a3714f45c3a99c1aa159e2d0b7e9c
Computational	Response to DNA damage.	DDX10 DDX11 RECQL4 HLTF KIF14 DDX23 DDX3Y TAP2	7.19e-05	187	80	8	MODULE_244
Drug	EPTC	AASDH KYAT1 CHRNA7 ALDH9A1 CHRFAM7A	1.78e-06	35	133	5	CID000012968
Drug	SB 202190; Down 200; 1uM; MCF7; HT_HG-U133A	ITSN1 SRC SLC7A11 BLVRA MYOF MAST4 CLCN3 ATP11A PUS7L	2.25e-06	195	133	9	6887_DN
Drug	11-keto-beta-boswellic acid	ENPP1 PREP LTA4H	1.07e-05	8	133	3	CID006918114
Drug	1,2-linoleoylphosphatidylcholine	ABCA1 APOA1 CHRNA7	1.07e-05	8	133	3	ctd:C002448
Drug	Erythromycin [114-07-8]; Up 200; 5.4uM; HL60; HG-U133A	UBL3 ITSN1 ICAM2 ABHD3 NUP214 MORC2 PUS7L CYB561	2.04e-05	196	133	8	2010_UP
Drug	Meticrane [1084-65-7]; Up 200; 14.6uM; HL60; HT_HG-U133A	ICAM2 SRC PTER ATP13A2 SCCPDH CEP41 PDCL CYB561	2.04e-05	196	133	8	1834_UP
Drug	(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; HL60; HT_HG-U133A	TRAF2 SLC4A8 SRC NLRP1 SLC35F5 CLCN4 SLC16A3 ATP11A	2.04e-05	196	133	8	2969_UP
Drug	vernolate	AASDH KYAT1 ALDH9A1	2.27e-05	10	133	3	CID000016003
Drug	Mefenamic acid [61-68-7]; Up 200; 16.6uM; HL60; HT_HG-U133A	ITSN1 MORC2 ATP13A2 CLCN3 CLCN4 CEP41 RTL8C CYB561	2.28e-05	199	133	8	1863_UP
Drug	4,4'-diisothiocyanostilbene-2,2'-disulfonic acid	SLC4A8 P2RY12 CLCN3 CLCN4 CLCN7 SLC34A1 SLC4A9 VDAC3	2.92e-05	206	133	8	CID000040600
Disease	osteopetrosis (implicated_via_orthology)	CLCN3 CLCN4 CLCN7	2.69e-06	7	127	3	DOID:13533 (implicated_via_orthology)
Disease	obesity (is_implicated_in)	ABCA1 ENPP1 SERPINF1 MC3R SLC6A3 MTTP	2.79e-06	91	127	6	DOID:9970 (is_implicated_in)
Disease	Apolipoprotein A-I deficiency	ABCA1 APOA1	1.84e-05	2	127	2	C0342898
Disease	hypolipoproteinemia (is_implicated_in)	ABCA1 APOA1	1.84e-05	2	127	2	DOID:1387 (is_implicated_in)
Disease	Familial hypoalphalipoproteinemia	ABCA1 APOA1	1.84e-05	2	127	2	cv:C1704429
Disease	Hypoalphalipoproteinemia, Familial	ABCA1 APOA1	1.84e-05	2	127	2	C1704429
Disease	anemia (implicated_via_orthology)	SLC4A8 SLC4A10 SLC4A9	3.41e-05	15	127	3	DOID:2355 (implicated_via_orthology)
Disease	Dent disease (implicated_via_orthology)	CLCN3 CLCN4	5.50e-05	3	127	2	DOID:0050699 (implicated_via_orthology)
Disease	Warsaw breakage syndrome (implicated_via_orthology)	DDX11 DDX11L8	5.50e-05	3	127	2	DOID:0060535 (implicated_via_orthology)
Disease	Crohn's disease (is_marker_for)	PON3 DUOX2 CHRNA7	2.62e-04	29	127	3	DOID:8778 (is_marker_for)
Disease	cognitive disorder (implicated_via_orthology)	CHRNA7 CHRFAM7A	2.73e-04	6	127	2	DOID:1561 (implicated_via_orthology)
Disease	rheumatoid arthritis (biomarker_via_orthology)	CHRNA7 CHRFAM7A	2.73e-04	6	127	2	DOID:7148 (biomarker_via_orthology)
Disease	non-alcoholic steatohepatitis (is_implicated_in)	SERPINF1 APOA1	2.73e-04	6	127	2	DOID:0080547 (is_implicated_in)
Disease	Developmental regression	CACNA1B NUP214	3.81e-04	7	127	2	C1836830
Disease	Nerve Degeneration	GRIN2D ATP13A2 CHRNA7 SLC6A3	4.62e-04	83	127	4	C0027746
Disease	Hypercholesterolemia	ABCA1 APOA1 MTTP	6.35e-04	39	127	3	C0020443
Disease	ulcerative colitis (is_marker_for)	PON3 DUOX2 CHRNA7	6.85e-04	40	127	3	DOID:8577 (is_marker_for)
Disease	familial hypercholesterolemia (is_implicated_in)	APOA1 MTTP	8.09e-04	10	127	2	DOID:13810 (is_implicated_in)
Disease	type 2 diabetes mellitus (is_implicated_in)	ABCA1 P2RY12 ENPP1 SERPINF1 SRC	8.87e-04	171	127	5	DOID:9352 (is_implicated_in)
Disease	nicotine dependence (implicated_via_orthology)	CHRNA7 CHRFAM7A	1.18e-03	12	127	2	DOID:0050742 (implicated_via_orthology)
Disease	peripheral arterial disease, traffic air pollution measurement	ABCA1 EPB41L4B GOLT1A SLC16A3 SLC34A1	1.55e-03	194	127	5	EFO_0004265, EFO_0007908
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	RPS6KA1 SLC43A3	1.62e-03	14	127	2	EFO_0006830, EFO_0006896
Disease	Hereditary Diffuse Gastric Cancer	ICAM2 APOA1 CLCN3 SLC16A3 PREP FKBP2	1.73e-03	293	127	6	C1708349
Disease	Stomach Neoplasms	ICAM2 APOA1 CLCN3 SLC16A3 PREP FKBP2	1.85e-03	297	127	6	C0038356
Disease	Malignant neoplasm of stomach	ICAM2 APOA1 CLCN3 SLC16A3 PREP FKBP2	1.94e-03	300	127	6	C0024623
Disease	rheumatoid arthritis (is_implicated_in)	BTNL2 SLC22A4 TAP2	2.02e-03	58	127	3	DOID:7148 (is_implicated_in)
Disease	coronary thrombosis, GM11992	EPB41L4B GPATCH1	2.12e-03	16	127	2	EFO_0001124, EFO_1000883
Disease	atherosclerosis (is_implicated_in)	PON3 APOA1	2.12e-03	16	127	2	DOID:1936 (is_implicated_in)
Disease	proprotein convertase subtilisin/kexin type 7 measurement	APOA1 DSCAML1	2.40e-03	17	127	2	EFO_0008270
Disease	Alzheimer's disease (is_implicated_in)	ABCA1 PON3 APOA1 TAP2	2.59e-03	132	127	4	DOID:10652 (is_implicated_in)
Disease	autoimmune thyroid disease, type 1 diabetes mellitus	BTNL2 TAP2	2.69e-03	18	127	2	EFO_0006812, MONDO_0005147
Disease	metabolite measurement	ALDH1L1 PTER KYAT1 MYOF SLC34A1 SLC22A4 GADL1 ALDH9A1	2.99e-03	560	127	8	EFO_0004725
Disease	familial hyperlipidemia (biomarker_via_orthology)	ABCA1 MTTP	3.00e-03	19	127	2	DOID:1168 (biomarker_via_orthology)
Disease	hippocampal tail volume	MAST4 SLC4A10	3.00e-03	19	127	2	EFO_0009398
Disease	squamous cell carcinoma	SRC MC1R ATP11A	3.05e-03	67	127	3	EFO_0000707
Disease	schizophrenia (implicated_via_orthology)	CHRNA7 SLC6A3 CHRFAM7A	3.18e-03	68	127	3	DOID:5419 (implicated_via_orthology)
Disease	Intellectual Disability	CACNA1B KDM3B GRIN2D SLC6A3 FRY ZDHHC9 SLC4A10	3.29e-03	447	127	7	C3714756
Disease	freckles	MC1R AKAP1	3.32e-03	20	127	2	EFO_0003963

Protein segments in the cluster

Peptide	Gene	Start	Entry
LAEGLKLTLDTIFVP	VDAC3	91	Q9Y277
LTGASIFLAPVLKFI	SLC4A9	821	Q96Q91
LELALTGGEAKSIPL	AKAP1	131	Q92667
VTLELGGKSPLIIFS	ALDH9A1	251	P49189
KIPIGFIPLGETSSL	AGK	146	Q53H12
SLLLKVAGLGSAPSI	BTNL2	136	Q9UIR0
AAGSKGLTIFPEELI	ADH4	301	P08319
LVKAGVLPLLTGAIT	ARMC6	216	Q6NXE6
VLKPGGSLFITTINK	COQ3	241	Q9NZJ6
VGFTLKIFASLLSPV	ABCA1	771	O95477
VLAQKFPEGLITGSL	CEP41	256	Q9BYV8
TLKFHDVVPGGIISL	ANKRD60	151	Q9BZ19
KESSFDIILSGLVPG	CIAPIN1	56	Q6FI81
TILLLPGLTGTSKES	ABHD3	141	Q8WU67
GDPLSLLFGDVTSLK	AMER1	306	Q5JTC6
KLVGTSVPGLLEIIL	AASDH	601	Q4L235
GLLPVLESFKVSFLS	APOA1	241	P02647
SGIPEIKTILSGFII	CLCN4	181	P51793
TIFLLSVGTALLGLK	CYB561	166	P49447
IKPGSSFGISVLRAL	CACNA1B	566	Q00975
VFLLPADSGEKISLG	CHRNA7	251	P36544
LKSFFIEGISDGIPL	NBEAL1	2311	Q6ZS30
GLKGAVTLTILLGIF	MC1R	236	Q01726
LTGIISKAALPGILS	NUP205	1676	Q92621
LTFVTPTLLAGDKSL	LTA4H	276	P09960
SFLPGICKELIGSSL	KIF14	1236	Q15058
FLGEKIASVLGISTP	FAM177A1	116	Q8N128
IPGGATLVFEVELLK	FKBP2	121	P26885
LGVPDTKAAFLLTIL	SLC16A3	256	O15427
SLGAVLFELLTGKTL	RPS6KC1	986	Q96S38
GSGKTLAFVIPILEI	DDX55	56	Q8NHQ9
GIGVTPFASILKDLV	DUOX2	1386	Q9NRD8
GLTVSAGVFIPSLLI	CLCN7	506	P51798
DLITPAKLSVGFELL	GPATCH1	146	Q9BRR8
APKRVEGLFLTLSGS	LCN8	51	Q6JVE9
SIISSKLGGFPISLA	MINDY4B	86	A8MYZ0
SGDPISVVKGLILLI	MTTP	721	P55157
GSLLGKTILPEASFL	NLRP1	441	Q9C000
TFTPLVDKLGLGSVV	KDM3B	121	Q7LBC6
GKLTIITSSLIPDIF	LACC1	176	Q8IV20
KLGELLFPSSLAGET	NUP214	1316	P35658
VAFSTLTGKIPTLLG	LRRC14B	286	A6NHZ5
TPGLRKVLFATALGT	MIGA2	41	Q7L4E1
VLTTILGCIFGLKPS	ENPP1	86	P22413
ILSDAKLGTGPLRTF	P2RY12	81	Q9H244
IFESPTGTGKSLSLI	DDX11	41	Q96FC9
GSGKTLAFLIPAVEL	DDX18	226	Q9NVP1
ETGSGKTAAFLIPLL	DDX23	436	Q9BUQ8
LFDGAIVSGKLLPSL	RALGAPA2	1796	Q2PPJ7
VFLLPADSGEKISLG	CHRFAM7A	161	Q494W8
KGTSFLLGGVVIVLL	GOLT1A	66	Q6ZVE7
LAVLTGEPLIFTVKA	PNPLA7	531	Q6ZV29
RLTPLTKFGEGDSTI	MDGA2	716	Q7Z553
IPGDSGTLVIIFNLK	MORC2	191	Q9Y6X9
IGVTILKAPSTKGIF	OR1J4	221	Q8NGS1
VLGLVEPSKLGRTLT	PTER	11	Q96BW5
GGKPEFTGSVSLLIL	PCDHA10	216	Q9Y5I2
VFTSAITPLIGLGVI	SLC34A1	421	Q06495
KITLTLVGLFLVPDG	SLC51A	191	Q86UW1
LTTGALLKTFPLDVG	PREP	366	P48147
ASVLTGKLTTVFLPI	F2RL1	66	P55085
TGALKIPGVIEFSLC	SLC37A1	321	P57057
GLLLVVDTTGKPNFI	FAXDC2	96	Q96IV6
ITDTGFKLLLLGLVT	ATP13A2	1111	Q9NQ11
LDGLPSTLAKSRGLV	HYDIN	3451	Q4G0P3
ALDTLFVPLLVGTGV	IGSF8	576	Q969P0
PIIFDLKEGTVSLIL	IFT80	366	Q9P2H3
GLVPGKSLVFATLEL	HEATR5A	1671	Q86XA9
KVSLLLGEPFFTTSL	PRMT7	471	Q9NVM4
KLFTIGCPVILATLG	DSCAML1	1591	Q8TD84
FLLLTQITKPLGSSG	ITSN1	1486	Q15811
IFESPTGTGKSLSLI	DDX11L8	41	A8MPP1
LKGSLLFTAGPLEEE	BLVRA	146	P53004
FLTGEPKVLGTVQIL	MS4A15	66	Q8N5U1
SKAVSGGLLPFALLE	MS4A18	251	Q3C1V0
KPEVFLSLGIVSLLE	MC3R	41	P41968
LSSGLLPKLAISTEG	MAST4	971	O15021
VSLGLAVSKPDLITF	KRBOX5	41	Q7Z2F6
LEVREIFLKTGLPST	EPS15	246	P42566
GSGKTLAFLVPVLEA	DDX10	116	Q13206
EKGLSGSPRLILFTS	GADL1	201	Q6ZQY3
ITIITTLFPKGSRGV	FRY	431	Q5TBA9
TTFLSLIEIPLKASG	HLTF	861	Q14527
SGKTAAFLLPILSQI	DDX3Y	226	O15523
LTIPLKGSSAAGELL	C4orf54	1471	D6RIA3
KVPLTTSLFFVGVLL	SLC22A4	141	Q9H015
LTPTGILIFEGANKI	EPB41L4B	291	Q9H329
FGLLPEKEVLVLTSV	PDCL	271	Q13371
VTGKPGELTLFSVLP	RPUSD3	101	Q6P087
DALKVTFLITRLTGP	RTL8A	61	Q9BWD3
DALKVTFLITRLTGP	RTL8B	61	Q17RB0
DALKVTFLITRLTGP	RTL8C	61	A6ZKI3
SPVISGGILEVFIKE	SYTL5	581	Q8TDW5
FGILLTELTTKGRVP	SRC	451	P12931
NLIFGSLVSITKSIP	SV2C	686	Q496J9
FTLSKLLAVILSIGG	SLC35F5	296	Q8WV83
TETEVIALGLPFGKV	PTBP2	71	Q9UKA9
LKLGRPTLSSEVGII	SCCPDH	61	Q8NBX0
GKTSLILSLVGEEFP	RHOT2	16	Q8IXI1
VGLGDPLSEISKLLE	PLEKHG4	151	Q58EX7
EAIGFLAIKLGVIPS	PUS7L	316	Q9H0K6
ISTLLVLPTGAGKSL	RECQL4	496	O94761
PLTKILASFFGELLG	KYAT1	71	Q16773
KPFLGLLGVLTVCIS	PTCHD4	261	Q6ZW05
LKGLTFTLRPGEVTA	TAP2	486	Q03519
VSLLQFPIFTLIKGS	SLC43A3	436	Q8NBI5
GSTGPVLVFEKILFK	SLC4A8	536	Q2Y0W8
ILTLQPTLVAVGKSF	ICAM2	116	P13598
LGLSGTFHIPVSKIV	SLC10A5	261	Q5PT55
TIFLIRGLTLPGATK	SLC6A18	221	Q96N87
SLELGGKSPLIIFAD	ALDH1L1	671	O75891
SGIVFVISGVLTLIP	CLDN6	121	P56747
IPEIKTILSGFIIRG	CLCN3	241	P51790
SGLPLFFVITVTAIK	ATP11A	96	P98196
SLELLQPGFSKTLLG	TRAF2	11	Q12933
TIIGAGIFISPKGVL	SLC7A11	56	Q9UPY5
KDILSPLFGTLVSSA	TDP1	186	Q9NUW8
LVFLGIDVSKPDLIT	ZNF738	71	Q8NE65
LKIGFLETLKETPGT	ZDHHC9	211	Q9Y397
TDTGALLFIGKILDP	SERPINF1	401	P36955
VTLGALKLPFGKTTV	UBL3	71	O95164
VSLGLVVSKPDLITF	ZNF267	41	Q14586
PILKGVGFTVILISL	SLC6A3	136	Q01959
LGSTGPVLVFEKILF	SLC4A10	566	Q6U841
RGPSLIKFKTGTAIL	ZHX1	771	Q9UKY1
PFVLIATGTVIILLG	TSPAN6	61	O43657
DILPSGLAFISSGLK	PON3	56	Q15166
KGLVLPFSEGLTVSS	PKHD1L1	2726	Q86WI1
ITVTSGSFLPALVLK	TTC21A	206	Q8NDW8
TEAEIISLGLPFGKV	PTBP3	71	O95758
FLLSPEAAVGLLKGT	TNPO3	551	Q9Y5L0
SILKVPEGFFSGLIL	VIRMA	1101	Q69YN4
LVAKLAITLFPFGSI	TMEM260	76	Q9NX78
TPEEILTRIGSGKFT	RPS6KA1	621	Q15418
SLELLKVRSLGGISP	MYO9A	1286	B2RTY4
GIPLDFSSSLGIIVK	MYOF	56	Q9NZM1
VLTPKEKGSTFLQLG	GRIN2D	151	O15399