Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-actinin binding

ITGB1 NRAP

5.78e-0431232GO:0051393
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

EP400 CHD7

8.25e-0437232GO:0140658
GeneOntologyMolecularFunctionactinin binding

ITGB1 NRAP

1.11e-0343232GO:0042805
GeneOntologyBiologicalProcessphotoreceptor cell morphogenesis

RABL2B RABL2A

3.89e-059222GO:0008594
GeneOntologyCellularComponentSwr1 complex

EP400 BRD8

8.97e-0513232GO:0000812
GeneOntologyCellularComponentintraciliary transport particle B

RABL2B RABL2A

2.40e-0421232GO:0030992
GeneOntologyCellularComponentintraciliary transport particle

RABL2B RABL2A

4.30e-0428232GO:0030990
GeneOntologyCellularComponentINO80-type complex

EP400 BRD8

4.30e-0428232GO:0097346
GeneOntologyCellularComponentpericentriolar material

RABL2B RABL2A

4.30e-0428232GO:0000242
GeneOntologyCellularComponentH4/H2A histone acetyltransferase complex

EP400 BRD8

5.63e-0432232GO:0043189
GeneOntologyCellularComponentNuA4 histone acetyltransferase complex

EP400 BRD8

5.63e-0432232GO:0035267
GeneOntologyCellularComponentH4 histone acetyltransferase complex

EP400 BRD8

1.11e-0345232GO:1902562
GeneOntologyCellularComponentglial cell projection

ADCY10 ITGB1

1.21e-0347232GO:0097386
GeneOntologyCellularComponentsperm midpiece

RABL2B RABL2A

2.24e-0364232GO:0097225
GeneOntologyCellularComponentintercalated disc

ITGB1 NRAP

2.52e-0368232GO:0014704
GeneOntologyCellularComponenthistone deacetylase complex

EP400 BRD8

3.91e-0385232GO:0000118
GeneOntologyCellularComponentcell-cell contact zone

ITGB1 NRAP

4.76e-0394232GO:0044291
GeneOntologyCellularComponenthistone acetyltransferase complex

EP400 BRD8

4.76e-0394232GO:0000123
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

EP400 BRD8

4.96e-0396232GO:0070603
GeneOntologyCellularComponentprotein acetyltransferase complex

EP400 BRD8

5.79e-03104232GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

EP400 BRD8

6.35e-03109232GO:1902493
GeneOntologyCellularComponentmotile cilium

ADCY10 RABL2B RABL2A

6.68e-03355233GO:0031514
GeneOntologyCellularComponentATPase complex

EP400 BRD8

8.78e-03129232GO:1904949
GeneOntologyCellularComponentnucleosome

EP400 BRD8

1.00e-02138232GO:0000786
DomainSNF2_N

EP400 CHD7

5.85e-0432212PF00176
DomainSNF2_N

EP400 CHD7

5.85e-0432212IPR000330
DomainDNA/RNA_helicase_DEAH_CS

EP400 CHD7

7.01e-0435212IPR002464
DomainDEAH_ATP_HELICASE

EP400 CHD7

8.26e-0438212PS00690
Domain-

EP400 ADCY10 CHD7 RABL2B RABL2A

1.20e-037462153.40.50.300
DomainSANT

EP400 CHD7

1.43e-0350212SM00717
DomainSANT/Myb

EP400 CHD7

1.54e-0352212IPR001005
DomainP-loop_NTPase

EP400 ADCY10 CHD7 RABL2B RABL2A

2.11e-03848215IPR027417
DomainRAB

RABL2B RABL2A

3.02e-0373212PS51419
DomainHelicase_C

EP400 CHD7

6.36e-03107212PF00271
DomainHELICc

EP400 CHD7

6.36e-03107212SM00490
DomainHelicase_C

EP400 CHD7

6.48e-03108212IPR001650
DomainHELICASE_CTER

EP400 CHD7

6.59e-03109212PS51194
DomainHELICASE_ATP_BIND_1

EP400 CHD7

6.59e-03109212PS51192
DomainDEXDc

EP400 CHD7

6.59e-03109212SM00487
DomainHelicase_ATP-bd

EP400 CHD7

6.71e-03110212IPR014001
DomainRas

RABL2B RABL2A

1.01e-02136212PF00071
DomainSmall_GTPase

RABL2B RABL2A

1.38e-02160212IPR001806
DomainSmall_GTP-bd_dom

RABL2B RABL2A

1.49e-02167212IPR005225
Pubmed

Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.

RABL2B RABL2A

4.18e-07223210444334
Pubmed

Variants in RABL2A causing male infertility and ciliopathy.

RABL2B RABL2A

4.18e-07223233075816
Pubmed

RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.

RABL2B RABL2A

4.18e-07223227732084
Pubmed

RABL2 positively controls localization of GPCRs in mammalian primary cilia.

RABL2B RABL2A

4.18e-07223230578315
Pubmed

Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing.

RABL2B RABL2A

4.18e-07223220138207
Pubmed

The p400/Brd8 chromatin remodeling complex promotes adipogenesis by incorporating histone variant H2A.Z at PPARγ target genes.

EP400 BRD8

2.51e-06423223064015
Pubmed

Genome-wide ENU mutagenesis to reveal immune regulators.

RABL2B RABL2A

2.51e-06423211567631
Pubmed

Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.

RABL2B RABL2A

4.18e-06523233241915
Pubmed

Ultrastructural and biochemical localization of N-RAP at the interface between myofibrils and intercalated disks in the mouse heart.

ITGB1 NRAP

1.50e-05923211732910
Pubmed

The highly conserved and multifunctional NuA4 HAT complex.

EP400 BRD8

2.29e-051123215196461
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

EP400 CHD7 BRD8 KNL1

2.72e-0526823433640491
Pubmed

The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.

RABL2B RABL2A

2.75e-051223228625565
Pubmed

ANP32E is a histone chaperone that removes H2A.Z from chromatin.

EP400 BRD8

2.75e-051223224463511
Pubmed

MRG15 is a novel PALB2-interacting factor involved in homologous recombination.

EP400 BRD8

2.75e-051223219553677
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

EP400 CHD7 BRD8 KNL1

3.32e-0528223423667531
Pubmed

Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy.

ITGB1 NRAP

4.99e-051623216717059
Pubmed

Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors.

RABL2B RABL2A

5.66e-051723230838872
Pubmed

Loss of Rab6a in the small intestine causes lipid accumulation and epithelial cell death from lactation.

DENND5B ITGB1

6.36e-051823232496646
Pubmed

Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.

EP400 BRD8

9.59e-052223212963728
Pubmed

MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.

EP400 BRD8

1.05e-042323220332121
Pubmed

Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

EP400 BRD8

1.05e-042323214966270
Pubmed

CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.

EP400 BRD8

1.05e-042323231281901
Pubmed

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.

EP400 BRD8

1.05e-042323222038470
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

EP400 CHD7 BRD8

1.21e-0414623323892456
Pubmed

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.

EP400 BRD8

2.46e-043523220946988
Pubmed

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.

EP400 BRD8

2.90e-043823227153538
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

EP400 BRD8

3.54e-044223235705031
Pubmed

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.

EP400 BRD8

3.54e-044223229028833
Pubmed

Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.

RABL2B RABL2A

4.44e-044723215172686
Pubmed

Hdac6 regulates Tip60-p400 function in stem cells.

EP400 BRD8

4.63e-044823224302573
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

EP400 PPIL2 CHD7 KNL1

5.55e-0458823438580884
GeneFamilyRAB like GTPases

RABL2B RABL2A

7.33e-065162394
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

EP400 CHD7

9.85e-0453162532
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_1000

DENND5B ZNF658 CHD7 BRD8 OSGIN2

1.40e-05311225gudmap_developingKidney_e13.5_podocyte cells_1000_k4
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500_k-means-cluster#4

DENND5B CHD7 RABL2A

4.43e-0567223Facebase_RNAseq_e9.5_Facial Mesenchyne_500_K4
CoexpressionAtlasdev gonad_e12.5_M_DevVasTestis_Flk_top-relative-expression-ranked_100

ENPP3 CHD7 PIEZO2

1.07e-0490223gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_100
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_top-relative-expression-ranked_100

ENPP3 CHD7 PIEZO2

1.14e-0492223gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_100
CoexpressionAtlasdev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_100

ENPP3 CHD7 PIEZO2

1.14e-0492223gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_100
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_500

ZNF658 CHD7 BRD8

1.38e-0498223gudmap_developingKidney_e13.5_podocyte cells_500_k3
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_1000

DENND5B ZNF658 CHD7 BRD8 PIEZO2 OSGIN2

1.79e-04855226gudmap_developingKidney_e13.5_podocyte cells_1000
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

ENPP3 PIEZO2 NRAP

1.62e-05962330fc179af7370a29b7bd5d81e1302a479ae72f196
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf|Cerebellum / BrainAtlas - Mouse McCarroll V32

ENPP3 PIEZO2 NRAP

1.62e-0596233c301ecfd67ece8bb12be1b94b614957a58046457
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2|Cerebellum / BrainAtlas - Mouse McCarroll V32

ENPP3 PIEZO2 NRAP

1.62e-05962337d402d543ff159c9bb84c00b083e6e18fc0ff786
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)|Cerebellum / BrainAtlas - Mouse McCarroll V32

ENPP3 PIEZO2 NRAP

1.62e-0596233a48235df1f5526ce3ffc4c0c2ba038eb20229c55
ToppCellLPS-antiTNF-Endothelial-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND5B ZNF658 LPAR3

5.43e-0514423375b16adfbe84f69376e6566d531ba7919d5c5192
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MIPOL1 ITGB1 ENPP3

6.50e-05153233764fb5e5fa028c137b8ea65dcd5e4ec9b22191e9
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MIPOL1 ITGB1 ENPP3

6.50e-05153233433b971c98da321204e065019db4e7825c7587cd
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

ADCY10 ITGB1 NPDC1

7.01e-05157233c44bd530e396b08f16f284e185dcb830843959ea
ToppCellLPS-antiTNF-Endothelial-Epi-like-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND5B ZNF658 LPAR3

7.01e-05157233abfd05ed993b80822739f47a735f154092a23632
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPDC1 PIEZO2 KNL1

8.42e-05167233b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPDC1 PIEZO2 KNL1

8.42e-0516723394fc7df7ca55cd722a8dbd153201a29891217473
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPDC1 PIEZO2 KNL1

8.42e-05167233eff3723fe60755272eca237459165e436e919ece
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

MOK ST3GAL5 MAP3K4

8.72e-0516923384b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ITGB1 LPAR3 CHD7

8.88e-05170233d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell(7)_MNP-(7)_DC_activated|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ADCY10 ST3GAL5 PIEZO2

8.88e-051702334ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ITGB1 NPDC1 MAP3K4

1.05e-04180233d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MOK RABL2B RABL2A

1.07e-04181233dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOK ST3GAL5 KNL1

1.09e-04182233bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ITGB1 NPDC1 MAP3K4

1.18e-04187233e1d6c1194476cf26969e405b0951796fed519f44
ToppCell5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPDC1 BRD8 PIEZO2

1.20e-04188233524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPDC1 BRD8 PIEZO2

1.20e-04188233f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPDC1 BRD8 PIEZO2

1.20e-041882331b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell5'-Airway_Nasal-Endothelial-Blood_vessel_EC|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPDC1 BRD8 PIEZO2

1.20e-04188233cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell5'-Airway_Nasal-Endothelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPDC1 BRD8 PIEZO2

1.20e-041882336c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

MOK RABL2B RABL2A

1.21e-041892333e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

NPDC1 CHD7 MAP3K4

1.25e-0419123325dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 NRAP PTPRU

1.27e-041922334fc98f30f8e738816cd93101fbe8ac40889e302a
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL5 PIEZO2 PTPRU

1.27e-041922331ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 NRAP PTPRU

1.27e-04192233be75783d9578974b662e1cb13bd3442a921fd50a
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

MOK RABL2B RABL2A

1.29e-04193233c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

MOK RABL2B RABL2A

1.29e-04193233ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

MOK RABL2B RABL2A

1.31e-04194233c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ITGB1 NPDC1 CHD7

1.33e-04195233e06ff785c5542c86c335d956799e03f7ae8345a4
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK RABL2B RABL2A

1.33e-041952333486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK RABL2B RABL2A

1.33e-04195233e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK RABL2B RABL2A

1.35e-0419623327b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MOK RABL2B RABL2A

1.35e-04196233d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MOK RABL2B RABL2A

1.37e-0419723371fea4aa6ce96c7693fa94792d08770622873850
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK RABL2B RABL2A

1.37e-04197233d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK RABL2B RABL2A

1.37e-04197233e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK RABL2B RABL2A

1.39e-04198233ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

ST3GAL5 CHD7 PTPRU

1.44e-042002332dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ENPP3 NRAP

6.60e-0474232a53f2e1f1044f3745a1eff5ba6275c8f1fbf3ae0
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ENPP3 NRAP

6.60e-0474232ae547cb8bbd780b19d9c6b555c27dad932dcc753
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ENPP3 NRAP

6.78e-0475232574ed1836f6bf5fa38a53af0a05fa4437f68f36b
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ENPP3 NRAP

6.78e-047523245f7861bfeb1c6371b73cf2ea527801342e534bc
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))|Striatum / BrainAtlas - Mouse McCarroll V32

ENPP3 KNL1

1.22e-031012320b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Cldn11_(Cldn11)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PIEZO2 NRAP

1.35e-031062325e01b9dd76a2f5904100de603310e6c0a553fbda
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Cldn11_(Cldn11)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PIEZO2 NRAP

1.35e-03106232be9de0f664395079fef9f3bbdffa651ea6f58be2
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LPAR3 ENPP3

1.50e-03112232ba0bd3a77c4865a71fb92d195cd7459c562b63db
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LPAR3 ENPP3

1.50e-03112232f9a796b4b5e227096ab360ca9ec08b1c564ac1eb
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LPAR3 ENPP3

1.50e-03112232153614f307525af56501ac8f9c357c5f7de7882c
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

ENPP3 NRAP

1.58e-0311523215b2c11225802cc15c01165d84a755432f02d82f
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ENPP3 KNL1

1.98e-03129232ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NPDC1 BRD8

2.01e-03130232c63f402d6ab71c2fcef12174b3139e55a727266c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ENPP3 PIEZO2

2.04e-031312329ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LPAR3 ENPP3

2.08e-03132232560e836764ed7806fb18282dfebe434d30112a9a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocye.Tnr.Ctps_(Ctps)|Striatum / BrainAtlas - Mouse McCarroll V32

LPAR3 PIEZO2

2.14e-03134232bc550d3b44f1e1e1c18971c110e816bcffd79d14
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr|Striatum / BrainAtlas - Mouse McCarroll V32

LPAR3 PIEZO2

2.14e-0313423290a34ae53a602a92f6f998e7cf061d8f4f0da527
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7|TCGA-Brain / Sample_Type by Project: Shred V9

MAP3K4 KNL1

2.20e-03136232d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_-_proliferative|E16.5-samps / Age Group, Lineage, Cell class and subclass

ADCY10 KNL1

2.20e-0313623296370f0e3abf1c9ec7a91595b5d0f97ac2ab4b78
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MOK ENPP3

2.30e-03139232f1d1a51a79afdddc82e73cd29b3240e3e973db28
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPDC1 PIEZO2

2.53e-03146232281144e293e8c93a425c2606d2188cb2838e667f
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B CHD7

2.63e-031492322cd860b96ed4be4d26844085d464961c1418054a
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

RABL2B RABL2A

2.63e-0314923241f28138bde45d0b814e116837e5a32b5e80d54a
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIPOL1 KNL1

2.67e-03150232973252f4de9a1194aea9f3cb0e1f113643f16c91
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LPAR3 PIEZO2

2.67e-031502328645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

RABL2B KNL1

2.67e-0315023298fdc6bdfde84d680e11d8727502b79afbf64303
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EP400 PPIL2

2.70e-031512327270b8bbfae659e110bd9d513b602120b25de3dd
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MOK BRD8

2.88e-031562320b3630fd4479291599e1674e87eba6f93877ac3a
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND5B RABL2B

2.92e-03157232bd45590da540a557dc8096980a45220fccb99505
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND5B RABL2B

2.92e-0315723200c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPDC1 PIEZO2

2.99e-03159232d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITGB1 NPDC1

2.99e-031592326599707107083af6da092fe8984afc8fd89d2bb8
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ITGB1 NPDC1

2.99e-03159232916d070d099726f22deb71966efccff00f8ea071
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B CHD7

3.03e-031602327ad065337ac802de52c15ee715f6b78a3eed0cef
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-LMPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EP400 MOK

3.03e-0316023260fa1c717410aad7e8647703cb416cd7617cac29
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tregs|Liver / Manually curated celltypes from each tissue

ITGB1 NPDC1

3.06e-03161232e0fd0c5f72d6a2900827e7bc2608ce3b8df5686b
ToppCell367C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ADCY10 KNL1

3.06e-03161232c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell367C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ADCY10 KNL1

3.06e-031612329864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB1 OSGIN2

3.06e-031612323f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ITGB1 NPDC1

3.06e-03161232580153e131247e6ec12a1a920f050a0a763e7e87
ToppCellInfluenza_Severe-B_memory|World / Disease group and Cell class

DENND5B CHD7

3.10e-0316223221eb96cd4fecd85dd6acbbc3760944fa1a7cff42
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|metastatic_Brain / Location, Cell class and cell subclass

RABL2A KNL1

3.18e-0316423206db4cc064f0765c481ce880207823872c27bfa9
ToppCelldroplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL5 LPAR3

3.18e-03164232a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LPAR3 ENPP3

3.22e-03165232570483b43ccb5831feec9337b4664814431d40b1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LPAR3 ENPP3

3.22e-031652322026a9a07f4d314cc05c167e491312b373468e46
ToppCellInfluenza_Severe-B_memory|Influenza_Severe / Disease group and Cell class

DENND5B CHD7

3.22e-0316523251172acaeb667b34b8b8c7878d67cfa0c4a2dffc
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ENPP3 PIEZO2

3.25e-03166232c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCellMild/Remission-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ST3GAL5 ITGB1

3.25e-0316623203e1a369d8a83b814def07e29cabb023226b4828
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

DENND5B KNL1

3.25e-031662328de8f388f24436b84e19ef460476fdbda4d16abf
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL5 KNL1

3.29e-031672321bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF658 NPDC1

3.33e-031682329e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell368C-Lymphocytic-NK_cells-NK_cell_C|368C / Donor, Lineage, Cell class and subclass (all cells)

MIPOL1 RABL2B

3.33e-031682320372c06b70f0ba95bf8cd1363ca7c5f31207f094
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ST3GAL5 OSGIN2

3.33e-031682324b5be7c6662eceddf90a65015f12908278d1664e
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B PTPRU

3.33e-031682323bddf411a60137a8883fc9e77586e4719b0d6067
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B PTPRU

3.33e-0316823206dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B PTPRU

3.33e-03168232b6d948857ee652351ddbe383b75fdd1721cd8721
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

MIPOL1 ENPP3

3.33e-0316823245ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

RABL2A KNL1

3.33e-031682324bf3f85aac4b335efa93d22c9ce7b153cb5ce152
DiseaseHypermetropia

CHD7 PTPRU

2.20e-03103202HP_0000540
Diseasetreatment-resistant hypertension

ST3GAL5 ENPP3

2.46e-03109202EFO_1002006
DiseaseEndometriosis

ITGB1 BRD8

5.27e-03161202C0014175
DiseaseEndometrioma

ITGB1 BRD8

5.27e-03161202C0269102
Diseaseblood phosphate measurement

ENPP3 KNL1

6.13e-03174202EFO_0010972
Diseaseurinary albumin to creatinine ratio

LPAR3 CHD7

6.47e-03179202EFO_0007778
Diseasedental caries

LPAR3 PIEZO2

7.04e-03187202EFO_0003819
Diseaseobsolete_red blood cell distribution width

EP400 MOK ST3GAL5 KNL1

1.17e-021347204EFO_0005192
Diseasemonocyte percentage of leukocytes

ST3GAL5 NPDC1 CHD7

1.26e-02731203EFO_0007989
Diseaselymphocyte count

ST3GAL5 NPDC1 CHD7 KNL1

1.55e-021464204EFO_0004587

Protein segments in the cluster

PeptideGeneStartEntry
MAQMRKQCLDYHYQE

EP400

361

Q96L91
MYNDSDHHVYHMAVE

BRD8

1181

Q9H0E9
HCKYYAHLAVMMQMN

ADCY10

1226

Q96PN6
HYNQYEQQKMHLMDQ

CHD7

71

Q9P2D1
HQKDKMYITCAEYTH

PPIL2

6

Q13356
CHLENNMYTMSHYYD

ITGB1

301

P05556
MHASYYHKAHACIMV

RABL2A

86

Q9UBK7
MHASYYHKAHACIMV

RABL2B

86

Q9UNT1
VHAKNSYMHCNERMY

NRAP

1466

Q86VF7
EKYNVMEHRHNDMHY

MIPOL1

81

Q8TD10
MNECHYDKHMDFFYN

LPAR3

1

Q9UBY5
HDSNYAKMYCNPDAM

KNL1

481

Q8NG31
MHYMYQLCKSLDHIH

MOK

106

Q9UQ07
NMVETMDQYHFCYDV

PTPRU

1421

Q92729
AEMYHYQHQRQQMLC

NPDC1

246

Q9NQX5
PEYHKVYHMMCTQSY

OSGIN2

351

Q9Y236
ADHGMDQTYCNKMEY

ENPP3

371

O14638
AMQTLYQMHNAEHYS

DENND5B

131

Q6ZUT9
HEYEHNFQIMYKVGM

MAP3K4

1546

Q9Y6R4
NYTTEECDMKKMHYV

ST3GAL5

86

Q9UNP4
ESIHMYYQNHIMNLS

PIEZO2

1701

Q9H5I5
EYNKVHMAMTHYECN

ZNF658

286

Q5TYW1
VEYNKVHMAMTHYEC

ZNF658B

41

Q4V348