Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlinoleic acid epoxygenase activity

CYP2C9 CYP2C18

7.44e-054712GO:0071614
GeneOntologyBiologicalProcesscell junction organization

SORT1 MAGI2 C1QL2 FLNA TENM4 EFNB2 FN1 NRXN2 ACTBL2 L1CAM FER PKHD1 ITGA6 SRCIN1 SLC7A11

7.32e-079747015GO:0034330
GeneOntologyBiologicalProcesscell-substrate adhesion

NDNF FLNA FN1 L1CAM FER PKHD1 ITGA6 SRCIN1 TNXB

9.89e-06410709GO:0031589
GeneOntologyBiologicalProcesssynapse organization

SORT1 MAGI2 C1QL2 FLNA TENM4 EFNB2 NRXN2 ACTBL2 L1CAM SRCIN1 SLC7A11

1.82e-056857011GO:0050808
GeneOntologyBiologicalProcesscell-cell adhesion

EPHB4 MAGI2 FLNA TENM4 EFNB2 NRXN2 L1CAM FER PKHD1 ITGA6 SLC7A11 PCDH1 TNXB

5.90e-0510777013GO:0098609
GeneOntologyBiologicalProcesspositive regulation of aorta morphogenesis

EPHB4 EFNB2

6.78e-054702GO:1903849
GeneOntologyBiologicalProcessneuroligin clustering involved in postsynaptic membrane assembly

MAGI2 NRXN2

6.78e-054702GO:0097118
GeneOntologyBiologicalProcesscell junction assembly

MAGI2 C1QL2 EFNB2 FN1 NRXN2 L1CAM FER ITGA6 SRCIN1

1.26e-04569709GO:0034329
GeneOntologyBiologicalProcesspositive regulation of cell-substrate adhesion

NDNF FLNA FN1 L1CAM ITGA6

1.53e-04149705GO:0010811
GeneOntologyBiologicalProcessregulation of aorta morphogenesis

EPHB4 EFNB2

1.69e-046702GO:1903847
GeneOntologyBiologicalProcessintracellular glutamate homeostasis

GLS SLC7A11

1.69e-046702GO:0090461
GeneOntologyBiologicalProcessreceptor clustering

MAGI2 FLNA NRXN2 SLC7A11

1.83e-0483704GO:0043113
GeneOntologyBiologicalProcessregulation of neuron projection development

MAGI2 NDNF FLNA EFNB2 FN1 L1CAM ITGA6 SRCIN1 NDRG4

2.18e-04612709GO:0010975
GeneOntologyBiologicalProcessregulation of cell-substrate adhesion

NDNF FLNA FN1 L1CAM PKHD1 ITGA6

2.23e-04254706GO:0010810
GeneOntologyBiologicalProcessregulation of cell adhesion

EPHB4 MAGI2 NDNF FLNA EFNB2 FN1 L1CAM PKHD1 ITGA6 SRCIN1 TNXB

2.71e-049277011GO:0030155
GeneOntologyBiologicalProcessneuron development

MAGI2 NDNF FLNA TENM4 EFNB2 FN1 KCNB1 ACTBL2 L1CAM ITGA6 KCNQ2 SRCIN1 TNXB NDRG4

3.44e-0414637014GO:0048666
GeneOntologyBiologicalProcesspositive regulation of artery morphogenesis

EPHB4 EFNB2

4.02e-049702GO:1905653
GeneOntologyCellularComponentextracellular matrix

TINAGL1 A2M NDNF FREM2 IL16 FN1 L1CAM ADAMTS20 ITGA6 TNXB

6.28e-056567010GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

TINAGL1 A2M NDNF FREM2 IL16 FN1 L1CAM ADAMTS20 ITGA6 TNXB

6.44e-056587010GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

TINAGL1 A2M FREM2 IL16 FN1 L1CAM ADAMTS20 ITGA6 TNXB

6.65e-05530709GO:0062023
GeneOntologyCellularComponentglutamatergic synapse

SORT1 MAGI2 C1QL2 FLNA TENM4 EFNB2 NRXN2 ACTBL2 L1CAM SRCIN1

3.73e-048177010GO:0098978
GeneOntologyCellularComponentfocal adhesion

FLNA FLNC IL16 EFNB2 L1CAM ITGA6 SRCIN1

5.91e-04431707GO:0005925
GeneOntologyCellularComponentcerebellar climbing fiber to Purkinje cell synapse

SORT1 C1QL2

5.96e-0411702GO:0150053
GeneOntologyCellularComponentactin cytoskeleton

ACTL7A FLNA FLNC ACTBL2 FER SRCIN1 TAF5 NEB

6.66e-04576708GO:0015629
GeneOntologyCellularComponentcell-substrate junction

FLNA FLNC IL16 EFNB2 L1CAM ITGA6 SRCIN1

6.95e-04443707GO:0030055
GeneOntologyCellularComponentiron-sulfur cluster assembly complex

GLRX3 NFS1

1.46e-0317702GO:1990229
GeneOntologyCellularComponentanchoring junction

MAGI2 FLNA FLNC IL16 EFNB2 L1CAM FER ITGA6 SRCIN1 PCDH1

1.46e-039767010GO:0070161
GeneOntologyCellularComponentZ disc

FLNA FLNC GLRX3 NEB

1.66e-03151704GO:0030018
GeneOntologyCellularComponentdendrite

SORT1 MAGI2 FLNA EFNB2 KCNB1 GLRX3 L1CAM SRCIN1 LSM1

2.19e-03858709GO:0030425
GeneOntologyCellularComponentdendritic tree

SORT1 MAGI2 FLNA EFNB2 KCNB1 GLRX3 L1CAM SRCIN1 LSM1

2.22e-03860709GO:0097447
GeneOntologyCellularComponentI band

FLNA FLNC GLRX3 NEB

2.34e-03166704GO:0031674
DomainCysteine_dSase

SCLY NFS1

1.38e-052702IPR016454
DomainGlc/Sorbosone_DH

HHIPL2 HHIPL1

4.14e-053702IPR012938
DomainGSDH

HHIPL2 HHIPL1

4.14e-053702PF07995
DomainIg_E-set

A2M FLNA FLNC PKHD1 ASCC3

4.41e-05104705IPR014756
DomainFN3

EPHB4 NDNF FLNC FN1 L1CAM TNXB

6.75e-05185706SM00060
DomainFN3_dom

EPHB4 NDNF FLNC FN1 L1CAM TNXB

1.32e-04209706IPR003961
DomainAA_TRANSFER_CLASS_5

SCLY NFS1

1.37e-045702PS00595
DomainPectin_lyas_fold

FBXO10 PKHD1

2.06e-046702IPR012334
DomainPbH1

FBXO10 PKHD1

2.06e-046702SM00710
Domain-

FBXO10 PKHD1

2.06e-0467022.160.20.10
DomainAminotran_5

SCLY NFS1

2.06e-046702PF00266
DomainPbH1

FBXO10 PKHD1

2.06e-046702IPR006626
DomainAminotrans_V_dom

SCLY NFS1

2.06e-046702IPR000192
DomainFolate_rcpt-like

HHIPL2 HHIPL1

3.82e-048702IPR018143
DomainPectin_lyase_fold/virulence

FBXO10 PKHD1

3.82e-048702IPR011050
DomainFolate_rec

HHIPL2 HHIPL1

3.82e-048702PF03024
Domain-

TENM4 HHIPL2 HHIPL1

4.18e-04397032.120.10.30
DomainIG_FLMN

FLNA FLNC

6.11e-0410702SM00557
Domain6-blade_b-propeller_TolB-like

TENM4 HHIPL2 HHIPL1

6.82e-0446703IPR011042
DomainFilamin

FLNA FLNC

7.45e-0411702PF00630
DomainFILAMIN_REPEAT

FLNA FLNC

7.45e-0411702PS50194
DomainFilamin/ABP280_rpt

FLNA FLNC

7.45e-0411702IPR001298
DomainFilamin/ABP280_repeat-like

FLNA FLNC

7.45e-0411702IPR017868
DomainQuinoprot_gluc/sorb_DH

HHIPL2 HHIPL1

8.92e-0412702IPR011041
DomainFN3

EPHB4 NDNF FN1 L1CAM TNXB

9.02e-04199705PS50853
DomainUDPGT

UGT2A3 UGT2A1

2.78e-0321702PF00201
DomainUDPGT

UGT2A3 UGT2A1

2.78e-0321702PS00375
DomainUDP_glucos_trans

UGT2A3 UGT2A1

2.78e-0321702IPR002213
DomainEGF-like_CS

EPHB4 TENM4 FN1 NRXN2 TNXB

2.96e-03261705IPR013032
Domainfn3

EPHB4 FN1 L1CAM TNXB

3.21e-03162704PF00041
Domain-

EPHB4 NDNF FLNA FLNC FN1 L1CAM PKHD1 TNXB

3.28e-036637082.60.40.10
DomainActinin_actin-bd_CS

FLNA FLNC

3.33e-0323702IPR001589
DomainACTININ_2

FLNA FLNC

3.33e-0323702PS00020
DomainACTININ_1

FLNA FLNC

3.33e-0323702PS00019
DomainIg-like_fold

EPHB4 NDNF FLNA FLNC FN1 L1CAM PKHD1 TNXB

4.79e-03706708IPR013783
DomainActin

ACTL7A ACTBL2

6.00e-0331702IPR004000
DomainActin

ACTL7A ACTBL2

6.00e-0331702PF00022
DomainACTIN

ACTL7A ACTBL2

6.00e-0331702SM00268
DomainVG_K_chnl

KCNB1 KCNQ2

6.78e-0333702IPR028325
PathwayKEGG_RETINOL_METABOLISM

CYP2C9 CYP2C18 UGT2A3 UGT2A1

8.88e-0564524M9488
PathwayREACTOME_BASIGIN_INTERACTIONS

L1CAM ITGA6 SLC7A11

1.03e-0425523M4974
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

CYP2C9 CYP2C18 UGT2A3 UGT2A1

1.26e-0470524M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

CYP2C9 CYP2C18 UGT2A3 UGT2A1

1.41e-0472524M9257
PathwayWP_AMINO_ACID_METABOLISM_IN_TRIPLENEGATIVE_BREAST_CANCER_CELLS

GLS SLC7A11

2.77e-047522M45522
Pubmed

Comparative mapping of the actin-binding protein 280 genes in human and mouse.

FLNA FLNC CLCN1

6.79e-0797138088838
Pubmed

Coexpression of EphB4 and ephrinB2 in tumor advancement of uterine cervical cancers.

EPHB4 EFNB2

4.11e-06271219356789
Pubmed

Titanium particle‑mediated osteoclastogenesis may be attenuated via bidirectional ephrin‑B2/eph‑B4 signaling in vitro.

EPHB4 EFNB2

4.11e-06271230015911
Pubmed

EphB4 promotes site-specific metastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinB2.

EPHB4 EFNB2

4.11e-06271221047731
Pubmed

Inhibition of EphB4-Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers.

EPHB4 EFNB2

4.11e-06271230894369
Pubmed

Ephrin‑B2 inhibits cell proliferation and motility in vitro and predicts longer metastasis‑free survival in breast cancer.

EPHB4 EFNB2

4.11e-06271231638179
Pubmed

EphrinB2-EphB4 signals regulate formation and maintenance of funnel-shaped valves in corneal lymphatic capillaries.

EPHB4 EFNB2

4.11e-06271223696610
Pubmed

Overexpression of EphB4, EphrinB2, and epidermal growth factor receptor in papillary thyroid carcinoma: A pilot study.

EPHB4 EFNB2

4.11e-06271224634162
Pubmed

Distribution of tubulointerstitial nephritis antigen-like 1 and structural matrix proteins in mouse embryos during preimplantation development in vivo and in vitro.

TINAGL1 FN1

4.11e-06271223021200
Pubmed

Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity.

EPHB4 EFNB2

4.11e-06271216867992
Pubmed

Ephrin B2 and EphB4 selectively mark arterial and venous vessels in cerebral arteriovenous malformation.

EPHB4 EFNB2

4.11e-06271224517927
Pubmed

Distinct roles of ephrin-B2 forward and EphB4 reverse signaling in endothelial cells.

EPHB4 EFNB2

4.11e-06271212588758
Pubmed

[Relationship between multi-slice spiral CT pulmonary perfusion imaging and the expression of EphB4 and ephrinB2 in non-small cell lung cancer].

EPHB4 EFNB2

4.11e-06271221575518
Pubmed

Differential expression of the receptor tyrosine kinase EphB4 and its ligand Ephrin-B2 during human placental development.

EPHB4 EFNB2

4.11e-06271216343615
Pubmed

Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines.

CYP2C9 CYP2C18

4.11e-06271222918969
Pubmed

EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.

EPHB4 EFNB2

4.11e-06271235725568
Pubmed

The differential expression of EPHB4 and ephrin B2 in cutaneous squamous cell carcinoma according to the grade of tumor differentiation: a clinicopathological study.

EPHB4 EFNB2

4.11e-06271233598934
Pubmed

Gene structure and upstream regulatory regions of human CYP2C9 and CYP2C18.

CYP2C9 CYP2C18

4.11e-0627128333835
Pubmed

Distribution of EphB4 and EphrinB2 in normal and malignant urogenital tissue.

EPHB4 EFNB2

4.11e-06271219272799
Pubmed

Expression of Eph B4 and Ephrin B2 in cervical cancer tissues and angiogenesis.

EPHB4 EFNB2

4.11e-06271217196593
Pubmed

A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesis.

EPHB4 EFNB2

4.11e-06271212051776
Pubmed

Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.

FLNA FLNC

4.11e-0627127689010
Pubmed

Cytochrome P450 2C9-induced angiogenesis is dependent on EphB4.

EPHB4 CYP2C9

4.11e-06271218340006
Pubmed

Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts.

EPHB4 EFNB2

4.11e-06271219035475
Pubmed

The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand.

EPHB4 EFNB2

4.11e-06271220649938
Pubmed

Vessel arterial-venous plasticity in adult neovascularization.

EPHB4 EFNB2

4.11e-06271222132096
Pubmed

Coexpression of EphB4 and ephrinB2 in tumour advancement of ovarian cancers.

EPHB4 EFNB2

4.11e-06271218231102
Pubmed

The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme.

EPHB4 EFNB2

4.11e-06271232567728
Pubmed

Substrate stiffness regulates arterial-venous differentiation of endothelial progenitor cells via the Ras/Mek pathway.

EPHB4 EFNB2

4.11e-06271228732675
Pubmed

Relationships among differentiation degree, contrast-enhanced ultrasound and the expression of Ephb4/Ephrinb2 in primary hepatocarcinoma.

EPHB4 EFNB2

4.11e-06271222024229
Pubmed

Treatment with ephrin B2 positively impacts the abnormal metabolism of human osteoarthritic chondrocytes.

EPHB4 EFNB2

4.11e-06271219664212
Pubmed

EphrinB2-EphB4 Signaling in Neurooncological Disease.

EPHB4 EFNB2

4.11e-06271235163601
Pubmed

Discovery and Characterization of Ephrin B2 and EphB4 Dysregulation and Novel Mutations in Cerebral Cavernous Malformations: In Vitro and Patient-Derived Evidence of Ephrin-Mediated Endothelial Cell Pathophysiology.

EPHB4 EFNB2

4.11e-06271238150042
Pubmed

Filamin isogene expression during mouse myogenesis.

FLNA FLNC

4.11e-06271210679933
Pubmed

Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells.

EPHB4 EFNB2

4.11e-06271212734395
Pubmed

Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma.

EPHB4 EFNB2

4.11e-06271217611172
Pubmed

EphB4 forward signalling regulates lymphatic valve development.

EPHB4 EFNB2

4.11e-06271225865237
Pubmed

EphrinB2/EphB4 Signaling Regulates DPSCs to Induce Sprouting Angiogenesis of Endothelial Cells.

EPHB4 EFNB2

4.11e-06271231017515
Pubmed

Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation.

EPHB4 EFNB2

4.11e-06271230075851
Pubmed

Inhibition of EphB4-Ephrin-B2 Signaling Enhances Response to Cetuximab-Radiation Therapy in Head and Neck Cancers.

EPHB4 EFNB2

4.11e-06271229848571
Pubmed

EphB4/EphrinB2 therapeutics in Rhabdomyosarcoma.

EPHB4 EFNB2

4.11e-06271228817624
Pubmed

Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrin-B2 during mammary gland morphogenesis.

EPHB4 EFNB2

4.11e-0627129718367
Pubmed

A novel structural unit in the N-terminal region of filamins.

FLNA FLNC

4.11e-06271224469451
Pubmed

The Effect of the NFκB-USP9X-Cx43 Axis on the Dynamic Balance of Bone Formation/Degradation during Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.

A2M FLNA FLNC AARS1

4.67e-065471435391932
Pubmed

Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos.

EPHB4 EFNB2 FN1

5.43e-061771318559979
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNA FLNC AARS1 NOP58 CLTCL1 GLRX3 PUF60 PSMA2 ACTBL2 MACROD1

5.51e-06807711030575818
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

TINAGL1 FLNA FREM2 NOP58 FN1 ACTBL2

5.93e-0621971631353912
Pubmed

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.

MAGI2 FLNA FLNC ATG4B GLRX3 L1CAM NDRG4

6.36e-0634171729791485
Pubmed

Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity.

EPHB4 EFNB2 FN1

6.51e-061871318651661
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

FLNA FLNC FN1

6.51e-061871312119179
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

TINAGL1 FN1 ADAMTS20 TNXB

9.23e-066471422261194
Pubmed

Isolation and characterization of fibronectin-alpha 1-microglobulin complex in rat plasma.

A2M FN1

1.23e-0537127519849
Pubmed

Expression of tenascin in developing and adult mouse lymphoid organs.

FN1 TNXB

1.23e-0537127687262
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNA FLNC

1.23e-05371211252955
Pubmed

The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.

FLNA FLNC

1.23e-05371212704190
Pubmed

The human CYP2C locus: a prototype for intergenic and exon repetition splicing events.

CYP2C9 CYP2C18

1.23e-05371210704292
Pubmed

Ephrin-B2-EphB4 communication mediates tumor-endothelial cell interactions during hematogenous spread to spinal bone in a melanoma metastasis model.

EPHB4 EFNB2

1.23e-05371232989254
Pubmed

Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities.

CYP2C9 CYP2C18

1.23e-05371215102943
Pubmed

Coexpression of ephrin-Bs and their receptors in colon carcinoma.

EPHB4 EFNB2

1.23e-05371211920461
Pubmed

Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.

FLNA FLNC

1.23e-05371211038172
Pubmed

Adhesive hierarchy involving the cell adhesion molecules L1, CD24, and alpha 6 integrin in murine neuroblastoma N2A cells.

L1CAM ITGA6

1.23e-0537127669058
Pubmed

Quantitative proteomics revealed novel proteins associated with molecular subtypes of breast cancer.

A2M FN1

1.23e-05371227498393
Pubmed

Endothelial EphB4 maintains vascular integrity and transport function in adult heart.

EPHB4 EFNB2

1.23e-05371231782728
Pubmed

Generation of transgenic mice overexpressing EfnB2 in endothelial cells.

EPHB4 EFNB2

1.23e-05371221735541
Pubmed

Whole-mount confocal microscopy for vascular branching morphogenesis.

EPHB4 EFNB2

1.23e-05371222222522
Pubmed

The clinical variability of the MECP2 duplication syndrome: description of two families with duplications excluding L1CAM and FLNA.

FLNA L1CAM

1.23e-05371219018795
Pubmed

Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.

FLNA FLNC

1.23e-05371211102480
Pubmed

Adaptive activation of EFNB2/EPHB4 axis promotes post-metastatic growth of colorectal cancer liver metastases by LDLR-mediated cholesterol uptake.

EPHB4 EFNB2

1.23e-05371236376513
Pubmed

Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.

FLNA FLNC

1.23e-05371217825253
Pubmed

EphrinB2/EphB4 inhibition in the osteoblast lineage modifies the anabolic response to parathyroid hormone.

EPHB4 EFNB2

1.23e-05371223165727
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNA FLNC

1.23e-05371212393796
Pubmed

Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.

UGT2A3 UGT2A1

1.23e-05371219858781
Pubmed

Cloning and expression of complementary DNAs for multiple members of the human cytochrome PH50IIC subfamily.

CYP2C9 CYP2C18

1.23e-0537128095407
Pubmed

Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.

FLNA FLNC

1.23e-0537129412467
Pubmed

Sinusoidal ephrin receptor EPHB4 controls hematopoietic progenitor cell mobilization from bone marrow.

EPHB4 EFNB2

1.23e-05371227820703
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNA FLNC

1.23e-05371211153914
Pubmed

Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis.

EPHB4 EFNB2 ITGA6

1.40e-052371319571816
Pubmed

Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily.

CYP2C9 CYP2C18

2.46e-0547122009263
Pubmed

Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes.

EPHB4 EFNB2

2.46e-05471218957513
Pubmed

Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development.

EPHB4 EFNB2

2.46e-05471210518221
Pubmed

The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.

FLNA FLNC

2.46e-05471220554076
Pubmed

Dynamic changes occur in patterns of endometrial EFNB2/EPHB4 expression during the period of spiral arterial modification in mice.

EPHB4 EFNB2

2.46e-05471218463357
Pubmed

Ephrin-B stimulation of calvarial bone formation.

EPHB4 EFNB2

2.46e-05471223129351
Pubmed

Genetic variation in the CYP2C monooxygenase enzyme subfamily shows no association with longevity in a German population.

CYP2C9 CYP2C18

2.46e-05471221798861
Pubmed

Erythropoietin Stimulates Tumor Growth via EphB4.

EPHB4 EFNB2

2.46e-05471226481148
Pubmed

CD9 of mouse brain is implicated in neurite outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1.

L1CAM ITGA6

2.46e-0547128838570
Pubmed

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.

FLNA FLNC

2.46e-05471211739414
Pubmed

Eph and ephrin expression in normal placental development and preeclampsia.

EPHB4 EFNB2

2.46e-05471215193868
Pubmed

Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis.

EPHB4 EFNB2

2.46e-05471216890539
Pubmed

Structural interaction and functional regulation of polycystin-2 by filamin.

FLNA FLNC

2.46e-05471222802962
Pubmed

Biochemistry and molecular biology of the human CYP2C subfamily.

CYP2C9 CYP2C18

2.46e-0547127704034
Pubmed

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.

CYP2C9 CYP2C18

2.46e-05471223755828
Pubmed

Immunocytochemical studies of adhesion molecules on mouse UNK cells and their extracellular matrix ligands during mouse pregnancy.

FN1 ITGA6

2.46e-05471220201059
Pubmed

Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development.

EFNB2 L1CAM

2.46e-05471215223333
Pubmed

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis.

EPHB4 EFNB2

2.46e-05471220445537
Pubmed

Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants.

EPHB4 EFNB2

2.46e-05471220101599
Pubmed

Syndecan-1 up-regulated by ephrinB2/EphB4 plays dual roles in inflammatory angiogenesis.

EPHB4 EFNB2

2.46e-05471215126321
Pubmed

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.

CYP2C9 CYP2C18

2.46e-05471219706858
Pubmed

EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity.

EPHB4 EFNB2

2.46e-05471232897857
Pubmed

Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo.

FLNA NEB

2.46e-05471216902413
InteractionKCND2 interactions

FLNA FLNC IL16 KCNB1

1.88e-0626704int:KCND2
Cytoband10q24

CYP2C9 CYP2C18

1.36e-033571210q24
Cytoband7q35

TCAF1 CLCN1

3.32e-03557127q35
GeneFamilyFibronectin type III domain containing

EPHB4 FN1 L1CAM TNXB

4.64e-04160414555
GeneFamilyUDP glucuronosyltransferases

UGT2A3 UGT2A1

2.38e-0332412363
GeneFamilyCytochrome P450 family 2

CYP2C9 CYP2C18

2.85e-03354121001
GeneFamilyPotassium voltage-gated channels

KCNB1 KCNQ2

3.71e-0340412274
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

SORT1 PLA2G7 NRM NDNF FREM2 OR10H5 TENM4 EFNB2 OR10H2 L1CAM PELI2 SLC7A11

8.66e-067837012gudmap_kidney_P4_CapMesRenVes_Crym_1000
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M FREM2 TENM4 PKHD1 ADAMTS20 KCNQ2 NEB

1.82e-081847172cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M FREM2 TENM4 PKHD1 ADAMTS20 KCNQ2 NEB

1.82e-08184717ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M FREM2 TENM4 PKHD1 ADAMTS20 KCNQ2 NEB

1.82e-081847172b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

TINAGL1 A2M EPHB4 EFNB2 KCNB1 ITGA6 PCDH1

2.53e-08193717e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 C1QL2 FLNA FREM2 FLNC KCNB1

5.44e-071877163912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 KCNB1 NRXN2 L1CAM KCNQ2 SRCIN1

6.55e-07193716be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 KCNB1 NRXN2 L1CAM KCNQ2 SRCIN1

6.55e-071937160c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 KCNB1 NRXN2 L1CAM KCNQ2 SRCIN1

6.55e-071937168689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

TINAGL1 A2M EPHB4 EFNB2 KCNB1 ITGA6

6.75e-071947167b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TINAGL1 FREM2 MACC1 KCNB1 UGT2A3 PKHD1

6.75e-071947168ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

TINAGL1 A2M EPHB4 EFNB2 ITGA6 PCDH1

6.95e-07195716fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

TINAGL1 A2M EPHB4 EFNB2 KCNB1 ITGA6

6.95e-0719571619e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

TINAGL1 A2M EPHB4 EFNB2 ITGA6 PCDH1

7.38e-07197716ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Capillary|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TINAGL1 A2M EFNB2 ITGA6 PCDH1 NDRG4

7.83e-071997163fea92affacd4c1f588fa81807df35d6c69b7241
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Capillary-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TINAGL1 A2M EFNB2 ITGA6 PCDH1 NDRG4

7.83e-07199716993999adf346b4fd557989bc53c17eb0ccb996c9
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 A2M EPHB4 EFNB2 FN1 ITGA6

7.83e-07199716a8f2eb00c3e4267a174bc9eff307dc2e5d18c76e
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TINAGL1 A2M FLNC EFNB2 FN1 PCDH1

7.83e-071997166a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Capillary|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TINAGL1 A2M EFNB2 ITGA6 PCDH1 NDRG4

7.83e-0719971689f4db619fbed90f7fdf6ece7a671e514b5c6d76
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TINAGL1 A2M EPHB4 EFNB2 PCDH1 NDRG4

8.06e-072007165ab588808c1fc384019413401ab4bf9bc06bf529
ToppCellParenchymal-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TINAGL1 A2M EPHB4 EFNB2 ITGA6 TNXB

8.06e-072007160e648e9eb96c83a94505d07323785a7a40997eb0
ToppCellLung_Parenchyma-Control-Endothelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TINAGL1 A2M EPHB4 EFNB2 ITGA6 NDRG4

8.06e-0720071641ac6adbf61763aa8a81a0ed586c4a5542a42cc5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FLNC EFNB2 FN1 TNXB NDRG4

8.06e-0720071693e13937ec74418a697c37d56f57509fb2154780
ToppCellBronchial-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TINAGL1 A2M EPHB4 EFNB2 PCDH1 NDRG4

8.06e-07200716ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TINAGL1 A2M EPHB4 EFNB2 ITGA6 NDRG4

8.06e-072007165109b417c066ecca0252008206b4f4b7a14c8702
ToppCellBiopsy_IPF-Endothelial|Biopsy_IPF / Sample group, Lineage and Cell type

TINAGL1 A2M EFNB2 ITGA6 TNXB NDRG4

8.06e-072007167ccd3b617838b39da814278dc0e12384013401ce
ToppCellParenchyma_Control_(B.)-Endothelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TINAGL1 A2M EPHB4 EFNB2 ITGA6 NDRG4

8.06e-072007169e5627e11288713aa9b622aae40e849dd6eacd29
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TINAGL1 A2M EPHB4 EFNB2 PCDH1 NDRG4

8.06e-072007166a3ccd0ea742fa76282c2b0fbc59942b4ef47bb8
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-3|TCGA-Endometrium / Sample_Type by Project: Shred V9

CYP2C9 CYP2C18 UGT2A3 L1CAM KCNQ2

5.25e-06157715ef70abc999be3a2c1eed7d21aef4b484f69d8567
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN1 HHIPL2 PKHD1 SLC7A11 PCDH1

6.68e-06165715936581de8fcd097401707438b9bbe89dd4e3e247
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M CYP2C18 FN1 HHIPL2 TNXB

8.41e-061737153877cead288ce9509e6cccf57e55ec5e1bd7ce18
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|367C / Donor, Lineage, Cell class and subclass (all cells)

TINAGL1 EFNB2 UGT2A1 KCNQ2 NDRG4

9.66e-06178715e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|367C / Donor, Lineage, Cell class and subclass (all cells)

TINAGL1 EFNB2 UGT2A1 KCNQ2 NDRG4

9.66e-06178715363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCellfacs-Heart-RA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 A2M EPHB4 PLA2G7 EFNB2

1.02e-05180715174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 MACC1 UGT2A3 PKHD1 DHRSX

1.05e-051817156956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

SORT1 A2M FLNA FN1 GLS

1.10e-05183715818fd886e0188091310825f9145fa53328f2c979
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SORT1 A2M FLNA FN1 GLS

1.10e-05183715cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellMesenchymal_cells-Smooth_muscle|Mesenchymal_cells / Lineage and Cell class

TINAGL1 FLNA KCNB1 ACSS1 PCDH1

1.13e-0518471583987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI2 TCAF1 TENM4 STOX1 TNXB

1.16e-051857156712512100ccef456d2e2bd201d0987986c92ac9
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

EFNB2 FN1 KCNQ2 SLC7A11 NDRG4

1.16e-05185715b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN2 ACSS1 L1CAM KCNQ2 PCDH1

1.16e-051857150149981d3818a6250f32c08456c28e7037c39d91
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

EFNB2 FN1 KCNQ2 SLC7A11 NDRG4

1.16e-05185715d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

A2M EFNB2 HHIPL2 ITGA6 NDRG4

1.19e-051867152e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

A2M EFNB2 HHIPL2 ITGA6 NDRG4

1.19e-05186715c3449e54454009973818fc1101933c6f0168258c
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.23e-0518771552ffd4be374e329ac8d321063f061b826d252956
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

A2M IL16 TENM4 FN1 TNXB

1.23e-05187715bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellEndothelial-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

TINAGL1 A2M PCDH1 TNXB NDRG4

1.23e-05187715febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

SORT1 A2M FLNA FN1 GLS

1.26e-0518871534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TINAGL1 A2M EFNB2 FN1 TNXB

1.26e-05188715a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCellEndothelial-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

TINAGL1 A2M PCDH1 TNXB NDRG4

1.26e-051887150824d567356d360fd8e78e840c30529c139f98a1
ToppCelldroplet-Lung-LUNG-30m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.29e-0518971525db316f66cee53774bb2b286cc457b37353356c
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SORT1 A2M FLNA FN1 GLS

1.29e-051897156b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellfacs-MAT-Fat-18m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.32e-0519071534e56c5e7ea6a8f227dbaefe73cbb8818d18b523
ToppCellfacs-MAT-Fat-18m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.32e-0519071514cdb660ad3aabcf49572173e7628d8b99dcbe6f
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.32e-05190715e64b191f928935484e2c993d7f8af0572a617a3a
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EFNB2 NRXN2 L1CAM KCNQ2 PCDH1

1.32e-051907154a777d8aa19cadd3b61b023772df142421a89113
ToppCellfacs-MAT-Fat-18m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.32e-051907159aaa48f3aad813c87a45efdbb67d255c94f6e6a4
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPHB4 FLNC EFNB2 ITGA6 TNXB

1.36e-05191715d25ac3206fe205a100cfee26431ff32c14c1938f
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.39e-05192715dfa6adc776621f4b51d731b796c0421855b2297c
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FLNA FREM2 FLNC FN1

1.39e-05192715d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.39e-051927156b69bb8fab9b470850eba1a070a500435ec233cd
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FLNA FREM2 FLNC KCNB1

1.43e-05193715173f1d83133f5ffa88e2a75d28835ad7acd2aa90
ToppCelldroplet-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.43e-051937157cff1e859b296b1032eebcfc0f99a504f3bda2c9
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TINAGL1 A2M EFNB2 PCDH1 NDRG4

1.43e-051937151e6e2d786511cc40241197368f5df20c20b882f3
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M MAGI2 IL16 FN1 TNXB

1.43e-0519371599525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCelldroplet-Lung-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.43e-0519371595c9c63bddfed1a84393ccd3578cfe65bc0c1c05
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 A2M EPHB4 FN1 ITGA6

1.43e-051937150f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FLNA FREM2 FLNC FN1

1.43e-051937150256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FLNA FREM2 FLNC KCNB1

1.46e-05194715bea369e9a7018d862e4d7f1c9ec2de50f3fd38ec
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FLNA FREM2 FLNC FN1

1.46e-05194715d2bafd31bb8333f66b6c714944bceb2f1aa11740
ToppCellCOPD-Endothelial-VE_Capillary_B|COPD / Disease state, Lineage and Cell class

TINAGL1 EFNB2 ITGA6 PCDH1 NDRG4

1.46e-0519471518b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.46e-05194715fc3f81b5bdc544a69c355e482f002643e029a7b0
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M NDNF TENM4 FN1 HHIPL2

1.50e-0519571530ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.50e-0519571552b2bbf12e5f86c493f6634697aeb23a68cc916d
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TINAGL1 A2M EFNB2 PCDH1 NDRG4

1.50e-0519571583da75d210ae9c2a94018d70cb9e833b37004c4e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 KCNB1 L1CAM KCNQ2 NDRG4

1.50e-05195715ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M EPHB4 EFNB2 FN1 ITGA6

1.50e-051957159ad4981c4d157edc752de206ab0d754aa14beab8
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.50e-05195715e5f14f6015ea5e6fa065f906ad22157e3de15c68
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN2 ACSS1 L1CAM KCNQ2 PCDH1

1.50e-051957159fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.50e-051957155b84fd5be31386eb1d6048bbf28626032361842e
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 A2M EPHB4 FN1 ITGA6

1.50e-05195715752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCellfacs-Heart-RA-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.50e-0519571530c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN2 ACSS1 L1CAM KCNQ2 PCDH1

1.54e-051967159afd0a7135028a446f06bb68f334e79b8f171b45
ToppCellfacs-Lung-ENDOMUCIN-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.54e-05196715f6df26ab9eebae893768a4f70a064ce9f60da93c
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN2 ACSS1 L1CAM KCNQ2 PCDH1

1.54e-05196715e874aa82a20bb59582c8cd7f8d30b2ed02903a85
ToppCellfacs-Lung-ENDOMUCIN|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.54e-0519671569f03546c42c942ab8ac8746167c8d44d574b4c6
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M MAGI2 IL16 FN1 TNXB

1.54e-05196715bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 A2M EFNB2 FN1 NDRG4

1.58e-0519771561b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell3'-Distal_airway-Endothelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TINAGL1 A2M EFNB2 PCDH1 NDRG4

1.58e-051977159ffb823c0f3f23cc85f9fd3ca24f77817e90bd86
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.58e-051977157caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.58e-05197715951f18f326967206adbbfc422cce9eea3d2e0854
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FLNA FREM2 FLNC FN1

1.58e-051977155a63c2b824c7d0dbbc706e408459c9b9fe65daaa
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TINAGL1 A2M EFNB2 PCDH1 NDRG4

1.61e-051987153aae7d146ebbb34da3239041a7c0334abff2597f
ToppCellnormal_Lung-Endothelial_cells-Stalk-like_ECs|normal_Lung / Location, Cell class and cell subclass

TINAGL1 A2M EPHB4 EFNB2 NDRG4

1.61e-051987152a251d13c2488d15ca9b11e643c1d17d428b6ef0
ToppCell(6)_Endothelial_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

TINAGL1 A2M EPHB4 EFNB2 ITGA6

1.61e-05198715f38f49d532fa6211f57e36ee494478bdd3f4f89c
ToppCell343B-Endothelial_cells|343B / Donor, Lineage, Cell class and subclass (all cells)

TINAGL1 A2M EFNB2 ITGA6 NDRG4

1.61e-05198715fab32347580c7a81ef1fe4fe7b325d9105a947d9
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 A2M EFNB2 FN1 NDRG4

1.61e-051987158a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCellILEUM-inflamed-(7)_CD36+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TINAGL1 A2M EFNB2 ITGA6 PCDH1

1.61e-0519871505d6558c7990ad2277db999025a073d29b273dfc
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 A2M EPHB4 EFNB2 ITGA6

1.61e-05198715e9e98c20ff7b3f3851db86381550ce7085e2db9e
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TINAGL1 A2M EFNB2 PCDH1 NDRG4

1.61e-05198715b11d21aa96a0c91e958ae7ed8fd56546aeaebb91
ToppCell368C-Endothelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

TINAGL1 EPHB4 EFNB2 ITGA6 PCDH1

1.61e-051987159a2c2201baee51581733e183065298a97eba4553
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

EPHB4 FN1 ITGA6 TNXB

5.36e-0550454GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_HEV_2
DiseaseX-21258 measurement

CYP2C9 CYP2C18

1.66e-053702EFO_0800802
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNC

1.66e-053702DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNC

1.66e-053702DOID:0111190 (implicated_via_orthology)
Diseaseglycine conjugate of C10H14O2 (1) measurement

CYP2C9 CYP2C18

1.16e-047702EFO_0800655
Diseasemyopathy (implicated_via_orthology)

FLNA FLNC CLCN1

2.05e-0448703DOID:423 (implicated_via_orthology)
Diseasepulse pressure measurement

EPHB4 CYP2C9 TENM4 FN1 UGT2A1 FER HHIPL1 PNKD NUP160 NDRG4 LSM1

4.13e-0413927011EFO_0005763
Diseasedepressive symptom measurement

KCNB1 PKHD1 ASCC3 SLC7A11 TNXB NUP160

5.26e-04426706EFO_0007006
DiseaseMAJOR AFFECTIVE DISORDER 2

MAGI2 KCNQ2

7.37e-0417702C1839839
Diseaseglomerulonephritis (is_marker_for)

PLA2G7 FN1

9.24e-0419702DOID:2921 (is_marker_for)
Diseasemetabolonic lactone sulfate measurement

CYP2C9 CYP2C18

9.24e-0419702EFO_0800659
Diseasecerebral infarction (is_marker_for)

A2M PLA2G7

9.24e-0419702DOID:3526 (is_marker_for)
Diseasecolorectal carcinoma (is_implicated_in)

EFNB2 MBD4

1.24e-0322702DOID:0080199 (is_implicated_in)
Diseasecomplement factor H-like 1 protein measurement

FREM2 KCNQ2

1.24e-0322702EFO_0600092
Diseasenephrotic syndrome (biomarker_via_orthology)

A2M PLA2G7

1.48e-0324702DOID:1184 (biomarker_via_orthology)
Diseaseglutamine measurement

TINAGL1 AARS1 GLS

1.61e-0397703EFO_0009768
DiseaseL lactate dehydrogenase measurement

TENM4 NUP160

1.74e-0326702EFO_0004808
DiseaseMental deterioration

TENM4 SLCO6A1

2.16e-0329702HP_0001268
DiseaseEarly Pregnancy Loss

IL16 FN1 GLS

2.24e-03109703C3830362
DiseaseMiscarriage

IL16 FN1 GLS

2.24e-03109703C4552766
DiseaseSpontaneous abortion

IL16 FN1 GLS

2.24e-03109703C0000786
DiseaseAbortion, Tubal

IL16 FN1 GLS

2.24e-03109703C0000822
DiseaseEpileptic encephalopathy

MAGI2 FLNA

2.31e-0330702C0543888

Protein segments in the cluster

PeptideGeneStartEntry
PYGVSYAHLKAEGKG

BAHCC1

436

Q9P281
PKGIVHTQAGYLLYA

ACSS1

301

Q9NUB1
SGDGVTHIVPIYEGY

ACTBL2

156

Q562R1
RGYVPAGKLQLYHVV

ARHGEF37

556

A1IGU5
AGIYILYHGNPVVSG

FBXO10

556

Q9UK96
IGGKPNSAHYFIGYV

ATG4B

256

Q9Y4P1
HYGYNVVVKIPAGAT

ADAMTS20

731

P59510
CGLYTYGKPVPGHVT

A2M

251

P01023
GTEYVHRYVGKEPSG

GLS

301

O94925
PKYGLIYHASLVGQT

NOP58

336

Q9Y2X3
VHYGFASVIYLKPKG

OR10H5

251

Q8NGA6
VHYGFASVIYLKPKG

OR10H2

251

O60403
VYVDGIPVAGKTHRY

MAGI2

826

Q86UL8
GHKIYGPKGVGAIYI

NFS1

256

Q9Y697
YLIGHGTKVYIDPFT

EPHB4

581

P54760
AYPHTVGKSVTGGYV

HHIPL1

466

Q96JK4
TYPQLYVKGELVGGL

GLRX3

301

O76003
DKSLVYIIRYGPGHG

FREM2

1336

Q5SZK8
HVGKKYGDIPRGIFV

LSM1

51

O15116
KVSGDYGHPVYIVQE

EFNB2

306

P52799
GLITLTTIGYGDKYP

KCNQ2

271

O43526
YGFPDVGHLYKLEVG

PCDH1

81

Q08174
PGTYTITIKYGGHPV

FLNC

1221

Q14315
PGKYVITIRFGGEHI

FLNC

1711

Q14315
YLIAIKYGGPQHIVG

FLNC

2571

Q14315
IVGGKDSIYGPIGIY

IL16

231

Q14005
VKGYIHYVFDLGNGP

NRXN2

971

Q9P2S2
QPGKSYLLDVYVIGH

NDNF

536

Q8TB73
YVLSYHPLDEGGKGQ

L1CAM

951

P32004
GLKQVYYHVLGLGEP

NRM

166

Q8IXM6
VGAPYDDLGKVFIYH

ITGA6

436

P23229
GSLPYEYKIVIAGNH

MPPED1

136

O15442
GEKYPLVVFSHGLGA

PLA2G7

141

Q13093
TTVGYGDIYPKTLLG

KCNB1

376

Q14721
FYVGLKSPHEGYEVL

C1QL2

161

Q7Z5L3
HGKPGEYVLSVYSDG

FER

486

P16591
LISIKYGGPYHIGGS

FLNA

2496

P21333
YTIKGLKPGVVYEGQ

FN1

666

P02751
AVTPELEGVGGHYLY

DHRSX

281

Q8N5I4
IHKTTSIGIYGPKYI

MACC1

366

Q6ZN28
KITGGYRLPAKYVIH

MACROD1

211

Q9BQ69
KYVIHTVGPIAYGEP

MACROD1

221

Q9BQ69
PIELHGIGKYGNDSY

MBD4

531

O95243
TVYFGLKPIVVLHGY

CYP2C18

66

P33260
TLYFGLKPIVVLHGY

CYP2C9

66

P11712
VLPIYAYGHAVGKSV

HHIPL2

486

Q6UWX4
LKILYGHSGPVYGAS

TAF5

536

Q15542
GPHYYTILDSGGIIV

SORT1

521

Q99523
YKGGIYSHTPVSLGR

TINAGL1

376

Q9GZM7
QGHLVYLLDGEPYKG

PNKD

231

Q8N490
PTTGKHKGYGFIEYE

PUF60

261

Q9UHX1
VKGAVHAPYYKLGET

TCAF1

631

Q9Y4C2
PVKYGELVVLGYNGA

PELI2

16

Q9HAT8
IGYALGYVLGAPLVK

SLCO6A1

276

Q86UG4
KYVIGIGVGAGAYVL

NDRG4

106

Q9ULP0
IDPGTIGVYGKVHLY

PKHD1

2846

P08F94
VLGKGHQYFGIEFPL

NUP160

1361

Q12769
VVEVGHGVSYVVPIY

ACTL7A

216

Q9Y615
PAHLVIIKGTEYYDG

ASCC3

1656

Q8N3C0
IGAKHGVIYLITKYG

CLTCL1

266

P53675
IYKILPGGYAVIGAA

CLCN1

516

P35523
KSGGHYTYILEVFGP

SLC7A11

106

Q9UPY5
VGHKFYGPRIGALYI

SCLY

256

Q96I15
GYVLHIGTIYGDLKV

AARS1

571

P49588
KGEGLYADPYGLLHE

SRCIN1

391

Q9C0H9
KIYHTGEGYFIVTPQ

STOX1

176

Q6ZVD7
LVTLYGFSDGKHVGP

TNXB

1946

P22105
HIGLVYSGMGPDYRV

PSMA2

71

P25787
FQIIIGYHGGLYDPL

TENM4

2396

Q6N022
GYHGGLYDPLTKLVH

TENM4

2401

Q6N022
NGIYEAIYHGVPMVG

UGT2A3

376

Q6UWM9
NGIYEAIYHGVPMVG

UGT2A1

376

P0DTE4
GSHDYPGEGIYLLKF

TMED8

291

Q6PL24
EGVTHYKAGDPVILY

TM9SF1

31

O15321
YLAGKVIGEFPGVVH

NEB

4506

P20929