Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium channel activity

TRPM7 TRPC4 GRIN2A

2.77e-04129203GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM7 TRPC4 GRIN2A

4.40e-04151203GO:0015085
DomainAAA+_ATPase

FIGN SNRNP200 DYNC1H1

3.97e-04144193IPR003593
DomainAAA

FIGN SNRNP200 DYNC1H1

3.97e-04144193SM00382
DomainIon_trans_dom

TRPM7 TRPC4

5.90e-03114192IPR005821
DomainIon_trans

TRPM7 TRPC4

5.90e-03114192PF00520
PathwayWP_RETT_SYNDROME

NCOR1 TCF4 GRIN2A

1.64e-0548153M39759
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM

PRNP GRIN2A

1.60e-0418152M47761
PathwayREACTOME_TRP_CHANNELS

TRPM7 TRPC4

3.93e-0428152MM14943
PathwayREACTOME_TRP_CHANNELS

TRPM7 TRPC4

3.93e-0428152M27241
Pubmed

Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex.

NCOR1 TCF4

1.88e-06420218632669
Pubmed

Prion protein is essential for the RE1 silencing transcription factor (REST)-dependent developmental switch in synaptic NMDA receptors.

PRNP GRIN2A

1.88e-06420229748616
Pubmed

Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles.

DYNC1H1 PRNP

6.59e-06720221335237
Pubmed

Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression.

TCF4 GRIN2A

1.13e-05920235535852
Pubmed

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.

TRPM7 TRPC4

1.41e-051020227177420
Pubmed

E protein silencing by the leukemogenic AML1-ETO fusion protein.

NCOR1 TCF4

2.85e-051420215333839
Pubmed

Mapping the expression of transient receptor potential channels across murine placental development.

TRPM7 TRPC4

8.61e-052420233884443
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

SNRNP200 DYNC1H1

8.61e-052420233705438
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPM7 TRPC4

9.35e-052520216382100
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

NCOR1 SNRNP200 TCF4 DYNC1H1 PARP2

1.02e-0485720525609649
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SNRNP200 DYNC1H1 PRNP PKP4 GRIN2A MGAT3

1.13e-04143120637142655
Pubmed

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.

TCF4 GRIN2A

1.35e-043020227568567
Pubmed

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

NCOR1 TCF4

1.35e-043020226593974
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPM7 TRPC4

1.64e-043320219834762
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOR1 DYNC1H1 PKP4 TRPC4 GRIN2A

1.77e-0496320528671696
Pubmed

Huntingtin interacting proteins are genetic modifiers of neurodegeneration.

NCOR1 DYNC1H1 PRNP

1.90e-0419720317500595
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPM7 TRPC4

2.18e-043820230786075
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

DNAJB12 NCOR1 SNRNP200 DYNC1H1

2.62e-0456020435241646
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

TRPM7 TRPC4

2.93e-044420219322198
Pubmed

Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes.

SNRNP200 DYNC1H1

3.64e-044920217567985
Pubmed

Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).

SNRNP200 DYNC1H1 PRNP

3.69e-0424720339238192
Pubmed

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.

TCF4 DYNC1H1

3.94e-045120216919471
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

NCOR1 SNRNP200 DYNC1H1

4.48e-0426420332814769
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

DYNC1H1 PKP4 GRIN2A

5.37e-0428120328706196
Pubmed

A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.

SNRNP200 DYNC1H1

5.63e-046120219875381
CytobandEnsembl 112 genes in cytogenetic band chr2q24

FIGN PKP4

1.40e-03127202chr2q24
GeneFamilyTransient receptor potential cation channels

TRPM7 TRPC4

2.74e-0428162249
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 TRPC4 GRIN2A

4.38e-0515520372a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TCF4 TRPC4

4.90e-051612031b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF4 PRNP GALNT9

4.99e-0516220375df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

5.56e-05168203d19a115365c5415e51c039718d7669de788fcf33
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TCF4 TRPC4

5.97e-0517220308a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TCF4 TRPC4

5.97e-05172203553701349444eb366df3c11f54bb093434f153c6
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

SNRNP200 TCF4 CSAD

6.17e-051742032274648b80dd74f3c948a779bba3391095964c34
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPT1C MGAT3 MAN2B2

6.50e-0517720330f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

TCF4 TRPC4 MGAT3

6.72e-05179203342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

7.06e-05182203d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

7.06e-0518220344764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

7.29e-05184203c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

7.29e-05184203e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 TRPC4 GRIN2A

7.65e-05187203e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 TRPC4 GRIN2A

7.65e-0518720324cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 TRPC4 GRIN2A

7.65e-051872032f153b203fe79f206319603cf94d3a03ab49a05d
ToppCelldroplet-Heart-HEART-1m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FIGN PRNP MGAT3

7.77e-05188203921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCelldroplet-Heart-HEART-1m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FIGN PRNP MGAT3

7.89e-051892034e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

7.89e-0518920371397e993a77d70b2eeede240bdfc7660b558987
ToppCelldroplet-Heart-HEART-1m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FIGN PRNP MGAT3

7.89e-05189203a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

7.89e-051892034eea4759520c312bd17a681034d8074e47093d2b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.14e-0519120339092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPQ NCOR1 PRNP

8.14e-05191203fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.14e-05191203ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.27e-05192203bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

NCOR1 TCF4 CSAD

8.27e-051922039cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.27e-051922035105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.27e-05192203d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.27e-051922030ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.40e-05193203c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.40e-05193203f1199518c3626fd29bfce65070dd21a660671213
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.40e-051932035b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.53e-05194203ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.53e-05194203cf0244a29934e515446ac917d3c30672b460fb04
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.53e-0519420381713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2|World / Primary Cells by Cluster

TCF4 PRNP GRIN2A

8.53e-05194203b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2-10|World / Primary Cells by Cluster

TCF4 PRNP GRIN2A

8.53e-0519420381e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.53e-05194203e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.53e-05194203627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FIGN TRPC4 GRIN2A

8.66e-051952033d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.66e-05195203edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.92e-05197203ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.92e-0519720337f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.92e-0519720309946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4 GRIN2A

8.92e-0519720380e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TCF4 DYNC1H1 PKP4

9.33e-052002035c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TCF4 DYNC1H1 PKP4

9.33e-0520020372ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FIGN TCF4 TRPC4

9.33e-052002030c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FIGN TCF4 TRPC4

9.33e-0520020394f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FIGN TCF4 TRPC4

9.33e-05200203522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

FIGN TCF4

1.32e-03121202b2d571f571133c281d72584fe925cebbd2317829
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

CPQ PRNP

1.50e-0312920213cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAM216B TCF4

1.64e-031352027743a01dc9c4542e910e7c0fe046004692a680bf
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FIGN CPQ

1.74e-03139202a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 GALNT9

1.79e-03141202cabb5b8c0874813c713508af2ac620ab0d61ab6f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 GALNT9

1.79e-031412023fa3d2a8ebd9c285168ecea6db9cad74d3a3e85a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CPT1C GALNT9

1.84e-0314320257ee1830d96d73d92b5f83b028592a5d952c6013
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PARP2 GALNT9

1.86e-03144202bdd6d00b2d1c9dad989df82367a60e8be79de816
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GALNT9 TRPC4

1.86e-0314420208005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

FAM216B GRIN2A

1.91e-03146202c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF4 MGAT3

1.99e-031492022cd860b96ed4be4d26844085d464961c1418054a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPT1C GRIN2A

2.02e-031502021270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPT1C GRIN2A

2.02e-03150202156118ce1d69522624196410cba18b8354cd0bb4
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FIGN PRNP

2.07e-0315220200d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 CSAD

2.18e-031562024d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM216B GALNT9

2.21e-03157202bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3|TCGA-Adrenal / Sample_Type by Project: Shred V9

FIGN TRPC4

2.32e-0316120252239a887799362256ecd7e740b716b88ed59a62
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4

2.35e-0316220282e782096f89cd03d1fdf599ba727d6f23e35e2d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4

2.35e-031622026bed33b17b59812646dc6a29c1d87413bad86c11
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN TRPC4

2.35e-03162202502ed67f6a572f10ac6e22948a1747d8214eb974
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 MGAT3

2.35e-031622028278dccdb139396ede34b83b02ebce837f2489d6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN GRIN2A

2.37e-031632028e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN GRIN2A

2.37e-03163202bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 CPT1C

2.40e-031642021592a5becad7e0f3f990f0d7581d75fcfc7da023
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 TRPC4

2.40e-03164202f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

TCF4 PKP4

2.43e-0316520284e553d699ac56df89a77248f7308b9133e1b683
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM216B TCF4

2.43e-03165202a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CPT1C GALNT9

2.43e-0316520215fd9d21dccfa80656a6fa3b72286a6a9252d403
ToppCellControl-Epithelial-Mesothelial|Control / Disease state, Lineage and Cell class

FIGN GALNT9

2.46e-031662021ed3788257e14f097862b999f020bfe2a57de52b
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

TCF4 MGAT3

2.46e-031662028de8f388f24436b84e19ef460476fdbda4d16abf
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

FAM216B TCF4

2.49e-03167202d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 GRIN2A

2.49e-031672023dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 GRIN2A

2.49e-031672029480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 GRIN2A

2.49e-0316720295b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

TCF4 CPT1C

2.49e-031672025af9127bae05768a5164d5708a4ad37edca99324
ToppCellIIH-naiveBc|IIH / Condition, Cell_class and T cell subcluster

TCF4 MGAT3

2.52e-031682028450ed6720d308c711dfbc76652e5821be7b8e93
ToppCellIIH-naiveBc-|IIH / Condition, Cell_class and T cell subcluster

TCF4 MGAT3

2.52e-0316820227b500f79aedc4669988670c92ff1a47dcbdf2a0
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TCF4 PARP2

2.55e-031692026614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TCF4 PARP2

2.55e-03169202665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 GRIN2A

2.55e-03169202a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCF4 PKP4

2.58e-031702021a568efcff9c39b3f709b55a05d24710450a2657
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN GRIN2A

2.58e-03170202fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FIGN GRIN2A

2.58e-0317020203044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TCF4 GRIN2A

2.58e-031702027fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCF4 PKP4

2.58e-0317020266d41d794790e621d72ac37af995510537103c9c
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FIGN GALNT9

2.58e-031702025570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCelldroplet-Kidney-nan-21m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSAD PRNP

2.61e-03171202007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCellcontrol-Myeloid-Eosinophils|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PRNP MGAT3

2.61e-0317120282f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKP4 MGAT3

2.61e-03171202b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 GRIN2A

2.64e-031722021ef243bce63d841c25e4b74d029d1377f84bcc3d
Drugflurbiprofen

TRPM7 NCOR1 TCF4 PRNP

1.35e-05171204CID000003394
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

DNAJB12 NCOR1 PRNP PARP2

1.77e-051832044770_DN
DrugFinasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A

DNAJB12 TCF4 PKP4 TRPC4

2.27e-051952044300_UP
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

NCOR1 TCF4 GRIN2A

4.81e-0649203DOID:0060037 (implicated_via_orthology)
DiseaseSevere Congenital Microcephaly

TCF4 DYNC1H1

2.01e-0431202C3853041
DiseaseMicrolissencephaly

TCF4 DYNC1H1

2.28e-0433202C1956147
Diseaseserine measurement

DYNC1H1 GRIN2A

2.56e-0435202EFO_0009774
Diseasebiological sex

FIGN TCF4 PKP4

4.83e-04230203PATO_0000047
DiseasePeripheral Nervous System Diseases

TCF4 CPT1C

6.12e-0454202C4721453
DiseaseAntihypertensive use measurement

FIGN TCF4 PKP4

7.29e-04265203EFO_0009927
DiseaseMicrocephaly

TCF4 DYNC1H1

9.40e-0467202C0025958
Diseasewellbeing measurement

FIGN TCF4 TRPC4 GRIN2A

1.08e-03692204EFO_0007869
Diseaseirritability measurement

TCF4 PRNP

1.40e-0382202EFO_0009594
DiseaseLiver Cirrhosis, Experimental

CPQ TCF4 CSAD PRNP

1.63e-03774204C0023893
Diseasesleep duration

CPQ TCF4 MGAT3

1.79e-03362203EFO_0005271
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

FIGN TCF4 TRPC4 GRIN2A

1.85e-03801204EFO_0003888, EFO_0007052, MONDO_0002491

Protein segments in the cluster

PeptideGeneStartEntry
EYDRTQPPMQYYNSQ

PKP4

1061

Q99569
VVYNQPYINYSRTVQ

CPQ

171

Q9Y646
NQGQQRYFYSIMRIY

FAM216B

36

Q8N7L0
YNEYIVYNPNQVRMR

PARP2

556

Q9UGN5
YSYGQQRSTQSPMYR

FIGN

336

Q5HY92
LRRRQYYTMPNFRQY

MGAT3

381

Q09327
YYTMPNFRQYENRTG

MGAT3

386

Q09327
NVYPEMRVYNNTLTY

GALNT9

451

Q9HCQ5
SQYYQYSSNNPRRRP

TCF4

146

P15884
YLRSRNPLMVNSNYY

CPT1C

241

Q8TCG5
NVHVYSNGRMRYTYQ

DNAJB12

216

Q9NXW2
NMYAVNLARYQRYPD

CSAD

156

Q9Y600
YQMQRRPYVSYVNNS

MAN2B2

736

Q9Y2E5
YVNNSIARNYYPMVQ

MAN2B2

746

Q9Y2E5
YMSNPSYNYEIVNRA

DYNC1H1

3371

Q14204
GYPSQYQLYAMENTR

NCOR1

1596

O75376
RSRTYNMIQYYQNDI

PI4KAP2

576

A4QPH2
RENMHRYPNQVYYRP

PRNP

151

P04156
YRRMTQNPNYYNLQG

SNRNP200

1761

O75643
TNYYYSAVERNNLMR

TRPM7

1551

Q96QT4
MAQFYYKRNVNAPYR

TRPC4

1

Q9UBN4
ERNIRNNYPYMHQYM

GRIN2A

691

Q12879