Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 TERT ERVK-8 ERVK-11	1.20e-10	14	120	6	GO:0003964
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 CSDE1 ERVK-8 ERVK-11	2.09e-09	21	120	6	GO:0035613
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 POLD1 ERVK-7 ERVK-10 TERT ERVK-8 ERVK-11	2.57e-09	38	120	7	GO:0034061
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	3.24e-09	11	120	5	GO:0004523
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 ENDOD1 POLD1 POLRMT ERVK-7 ERVK-10 PXDNL ERVK-8 MARF1 ERVK-11	1.35e-06	231	120	10	GO:0004518
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	2.69e-06	37	120	5	GO:0016891
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 POLD1 POLRMT ERVK-7 ERVK-10 TERT ERVK-8 ERVK-11	3.83e-06	152	120	8	GO:0016779
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	8.11e-06	46	120	5	GO:0016893
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 POLRMT ERVK-7 ERVK-10 ERVK-8 MARF1 ERVK-11	1.83e-05	136	120	7	GO:0004540
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ENDOD1 ERVK-7 ERVK-10 PXDNL ERVK-8 ERVK-11	1.83e-05	136	120	7	GO:0004519
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	7.03e-05	37	120	4	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	7.82e-05	38	120	4	GO:0070001
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.14e-04	79	120	5	GO:0004521
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERVK-6 RIPK1 POLD1 ROR2 POLRMT BAZ1B SOSTDC1 ERVK-7 ERVK-10 TERT TYK2 MST1R FCSK ERVK-8 PAK3 ERVK-11	1.57e-04	938	120	16	GO:0016772
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	ERVK-6 ENDOD1 POLD1 POLRMT ERVK-7 ERVK-10 MINPP1 ACOT4 ARSA PPP3CC PXDNL ERVK-8 MARF1 ERVK-11	3.50e-04	807	120	14	GO:0016788
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ERVK-6 POLD1 ERVK-7 ERVK-10 TERT ERVK-8 ERVK-11	1.04e-03	262	120	7	GO:0140097
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-6 ADAM19 PRSS12 ERVK-7 ADAMTS13 ERVK-10 PROZ ERVK-8 CAPN15	1.17e-03	430	120	9	GO:0004175
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	7.92e-09	13	121	5	GO:0015074
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 POLD1 ERVK-7 ERVK-10 ERVK-8 ERVK-11	3.61e-07	48	121	6	GO:0000731
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-6 ERVK-7 ERVK-10 TERT ERVK-8 ERVK-11 PML	5.76e-07	83	121	7	GO:0006278
GeneOntologyBiologicalProcess	DNA biosynthetic process	ERVK-6 POLD1 ERVK-7 ERVK-10 TERT ERVK-8 PAK3 TNF ERVK-11 PML	6.45e-07	218	121	10	GO:0071897
GeneOntologyBiologicalProcess	DNA-templated DNA replication	ERVK-6 POLD1 POLRMT ERVK-7 ERVK-10 ERVK-8 ERVK-11	8.75e-05	178	121	7	GO:0006261
Domain	CCP	CD55 APOH CSMD2 SNED1 SEZ6	1.85e-05	54	113	5	SM00032
Domain	SUSHI	CD55 APOH CSMD2 SNED1 SEZ6	2.22e-05	56	113	5	PS50923
Domain	Sushi_SCR_CCP_dom	CD55 APOH CSMD2 SNED1 SEZ6	2.42e-05	57	113	5	IPR000436
Domain	ARHGEF5_35	ARHGEF5 ARHGEF35	3.63e-05	2	113	2	PF15441
Domain	ARHGEF5/35_N	ARHGEF5 ARHGEF35	3.63e-05	2	113	2	IPR029212
Domain	RT_dom	ERVK-6 TERT	3.63e-05	2	113	2	IPR000477
Domain	RVT_1	ERVK-6 TERT	3.63e-05	2	113	2	PF00078
Domain	RT_POL	ERVK-6 TERT	3.63e-05	2	113	2	PS50878
Domain	WW_DOMAIN_1	SMURF1 ARHGAP9 CEP164 SMURF2	2.55e-04	51	113	4	PS01159
Domain	WW_DOMAIN_2	SMURF1 ARHGAP9 CEP164 SMURF2	2.55e-04	51	113	4	PS50020
Domain	WW_dom	SMURF1 ARHGAP9 CEP164 SMURF2	2.75e-04	52	113	4	IPR001202
Domain	Sushi	CD55 APOH CSMD2 SEZ6	2.75e-04	52	113	4	PF00084
Domain	CUB	ADAMTS13 CSMD2 SCUBE3 SEZ6	2.96e-04	53	113	4	PS01180
Domain	CUB_dom	ADAMTS13 CSMD2 SCUBE3 SEZ6	3.92e-04	57	113	4	IPR000859
Domain	Semap_dom	SEMA3G PLXND1 MST1R	8.57e-04	31	113	3	IPR001627
Domain	SEMA	SEMA3G PLXND1 MST1R	8.57e-04	31	113	3	PS51004
Domain	Sema	SEMA3G PLXND1 MST1R	8.57e-04	31	113	3	SM00630
Domain	Sema	SEMA3G PLXND1 MST1R	8.57e-04	31	113	3	PF01403
Domain	Plexin_repeat	SEMA3G PLXND1 MST1R	9.41e-04	32	113	3	IPR002165
Domain	PSI	SEMA3G PLXND1 MST1R	9.41e-04	32	113	3	PF01437
Domain	Ig_I-set	MAG LRFN3 ROR2 LINGO1 PXDNL MYPN	1.05e-03	190	113	6	IPR013098
Domain	I-set	MAG LRFN3 ROR2 LINGO1 PXDNL MYPN	1.05e-03	190	113	6	PF07679
Domain	VWFC_1	SSPOP NELL2 PXDNL	1.33e-03	36	113	3	PS01208
Domain	VWFC_2	SSPOP NELL2 PXDNL	1.56e-03	38	113	3	PS50184
Domain	VWC	SSPOP NELL2 PXDNL	1.56e-03	38	113	3	SM00214
Domain	VWF_dom	SSPOP NELL2 PXDNL	2.08e-03	42	113	3	IPR001007
Domain	-	MAG IL12RB2 LRFN3 ROR2 SEMA3G PLXND1 MST1R SNED1 LINGO1 PXDNL MYPN	2.27e-03	663	113	11	2.60.40.10
Domain	PSI	SEMA3G PLXND1 MST1R	2.38e-03	44	113	3	IPR016201
Domain	PSI	SEMA3G PLXND1 MST1R	2.71e-03	46	113	3	SM00423
Domain	WW	SMURF1 CEP164 SMURF2	3.06e-03	48	113	3	SM00456
Domain	IGc2	MAG LRFN3 ROR2 LINGO1 PXDNL MYPN	3.07e-03	235	113	6	SM00408
Domain	EGF_3	ADAM19 SSPOP SNED1 NELL2 PROZ SCUBE3	3.07e-03	235	113	6	PS50026
Domain	Ig_sub2	MAG LRFN3 ROR2 LINGO1 PXDNL MYPN	3.07e-03	235	113	6	IPR003598
Domain	ASX_HYDROXYL	SNED1 NELL2 PROZ SCUBE3	3.19e-03	100	113	4	PS00010
Domain	CUB	CSMD2 SCUBE3 SEZ6	3.24e-03	49	113	3	PF00431
Domain	CUB	CSMD2 SCUBE3 SEZ6	3.44e-03	50	113	3	SM00042
Domain	Ig-like_fold	MAG IL12RB2 LRFN3 ROR2 SEMA3G PLXND1 MST1R SNED1 LINGO1 PXDNL MYPN	3.67e-03	706	113	11	IPR013783
Domain	-	CSMD2 SCUBE3 SEZ6	3.84e-03	52	113	3	2.60.120.290
Domain	EGF-type_Asp/Asn_hydroxyl_site	SNED1 NELL2 PROZ SCUBE3	3.93e-03	106	113	4	IPR000152
Domain	-	NOL10 SEMA3G PLXND1 DDB2 WDR93 MST1R LLGL1	4.14e-03	333	113	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	NOL10 SEMA3G PLXND1 DDB2 WDR93 MST1R LLGL1	4.28e-03	335	113	7	IPR015943
Domain	EGF_1	ADAM19 SSPOP SNED1 NELL2 PROZ SCUBE3	4.58e-03	255	113	6	PS00022
Domain	Kringle_CS	PRSS12 ROR2	4.65e-03	17	113	2	IPR018056
Domain	KRINGLE_1	PRSS12 ROR2	4.65e-03	17	113	2	PS00021
Domain	KR	PRSS12 ROR2	4.65e-03	17	113	2	SM00130
Domain	Kringle	PRSS12 ROR2	4.65e-03	17	113	2	IPR000001
Domain	KRINGLE_2	PRSS12 ROR2	4.65e-03	17	113	2	PS50070
Domain	Kringle	PRSS12 ROR2	4.65e-03	17	113	2	PF00051
Domain	CTCK_1	SOSTDC1 SSPOP	5.21e-03	18	113	2	PS01185
Domain	EGF_2	ADAM19 SSPOP SNED1 NELL2 PROZ SCUBE3	5.50e-03	265	113	6	PS01186
Domain	VWC_out	SSPOP NELL2	5.80e-03	19	113	2	SM00215
Pubmed	The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	8.13e-17	8	133	7	17588759
Pubmed	DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.21e-15	10	133	7	17984056
Pubmed	Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	7.95e-15	12	133	7	10433963
Pubmed	Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.72e-14	13	133	7	17668377
Pubmed	Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.72e-14	13	133	7	7739628
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.92e-13	17	133	7	11245978
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	2.18e-07	4	133	3	10469592
Pubmed	Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.	SMURF1 TNF SMURF2	2.18e-07	4	133	3	16373342
Pubmed	The functions and regulation of Smurfs in cancers.	SMURF1 SMURF2	1.45e-05	2	133	2	31899247
Pubmed	Positive feedback-loop of telomerase reverse transcriptase and 15-lipoxygenase-2 promotes pulmonary hypertension.	TERT ALOX15B	1.45e-05	2	133	2	24376652
Pubmed	The P2X7-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATP.	MYH9 P2RX7	1.45e-05	2	133	2	20007545
Pubmed	SMURF1 and SMURF2 in Progenitor Cells from Articular Cartilage and Meniscus during Late-Stage Osteoarthritis.	SMURF1 SMURF2	1.45e-05	2	133	2	33090007
Pubmed	Synthetic prostacyclin analogs differentially regulate macrophage function via distinct analog-receptor binding specificities.	PTGER2 TNF	1.45e-05	2	133	2	17237412
Pubmed	RIPK1 protects hepatocytes from Kupffer cells-mediated TNF-induced apoptosis in mouse models of PAMP-induced hepatitis.	RIPK1 TNF	1.45e-05	2	133	2	28088582
Pubmed	Microarray analysis revealing common and distinct functions of promyelocytic leukemia protein (PML) and tumor necrosis factor alpha (TNFα) signaling in endothelial cells.	TNF PML	1.45e-05	2	133	2	22947142
Pubmed	Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons.	GPR179 TRPM1	1.45e-05	2	133	2	24114537
Pubmed	PML-IV functions as a negative regulator of telomerase by interacting with TERT.	TERT PML	1.45e-05	2	133	2	19567472
Pubmed	Ca(2+) spiking activity caused by the activation of store-operated Ca(2+) channels mediates TNF-α release from microglial cells under chronic purinergic stimulation.	P2RX7 TNF	1.45e-05	2	133	2	23830920
Pubmed	Mechanism of microglia neuroprotection: Involvement of P2X7, TNFα, and valproic acid.	P2RX7 TNF	1.45e-05	2	133	2	26295445
Pubmed	A mental retardation gene, motopsin/prss12, modulates cell morphology by interaction with seizure-related gene 6.	PRSS12 SEZ6	1.45e-05	2	133	2	23770366
Pubmed	Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis.	MYH9 RIPK1	1.45e-05	2	133	2	30420430
Pubmed	Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.	SMURF1 SMURF2	1.45e-05	2	133	2	18927080
Pubmed	Anti-beta2 glycoprotein I antibodies cause inflammation and recruit dendritic cells in platelet clearance.	APOH TNF	1.45e-05	2	133	2	11816715
Pubmed	Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer.	SMURF1 FAF2 SMURF2	1.93e-05	14	133	3	29263404
Pubmed	Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.	DUX4L2 TNF DUX4L4	2.41e-05	15	133	3	35727972
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	3.17e-05	94	133	5	21542922
Pubmed	MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL.	RIPK1 NEURL3 TNF	3.57e-05	17	133	3	33469115
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DIP2B ARHGEF5 POLRMT FANCA TYK2 CSDE1 LLGL1 GTF3C1 AP5B1 ARMC5 MARF1	4.30e-05	650	133	11	38777146
Pubmed	The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.	RIPK1 TNF	4.34e-05	3	133	2	22016814
Pubmed	The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1.	SMURF1 SMURF2	4.34e-05	3	133	2	23475958
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-11	4.34e-05	3	133	2	9971820
Pubmed	Telomerase suppression initiates PML-dependent p53 activation to inhibit bladder cancer cell growth.	TERT PML	4.34e-05	3	133	2	21042751
Pubmed	Inhibition of caspases primes colon cancer cells for 5-fluorouracil-induced TNF-α-dependent necroptosis driven by RIP1 kinase and NF-κB.	RIPK1 TNF	4.34e-05	3	133	2	26522725
Pubmed	Ubiquitin-specific protease 4 promotes TNF-α-induced apoptosis by deubiquitination of RIP1 in head and neck squamous cell carcinoma.	RIPK1 TNF	4.34e-05	3	133	2	23313255
Pubmed	[TLR2 blockade reduces TNF-α expression induced by β2GP1/anti-β2GP1 complex in mouse peritoneal macrophages].	APOH TNF	4.34e-05	3	133	2	27053607
Pubmed	RIPK1 suppresses apoptosis mediated by TNF and caspase-3 in intervertebral discs.	RIPK1 TNF	4.34e-05	3	133	2	31029152
Pubmed	Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis.	RIPK1 TNF	4.34e-05	3	133	2	17996648
Pubmed	Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma.	SMURF1 SMURF2	4.34e-05	3	133	2	37537194
Pubmed	Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2.	SMURF1 SMURF2	4.34e-05	3	133	2	25051198
Pubmed	Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.	IL12RB2 P2RX7	4.34e-05	3	133	2	19767732
Pubmed	Ubiquitin-specific peptidase 21 inhibits tumor necrosis factor alpha-induced nuclear factor kappaB activation via binding to and deubiquitinating receptor-interacting protein 1.	RIPK1 TNF	4.34e-05	3	133	2	19910467
Pubmed	Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.	SMURF1 SMURF2	4.34e-05	3	133	2	24925320
Pubmed	TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production.	RIPK1 TNF	4.34e-05	3	133	2	26381601
Pubmed	MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.	RIPK1 TNF	4.34e-05	3	133	2	28506461
Pubmed	USF2 inhibits the transcriptional activity of Smurf1 and Smurf2 to promote breast cancer tumorigenesis.	SMURF1 SMURF2	4.34e-05	3	133	2	30244169
Pubmed	Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.	SMURF1 SMURF2	4.34e-05	3	133	2	15173588
Pubmed	The prostaglandin EP4 receptor is a master regulator of the expression of PGE2 receptors following inflammatory activation in human monocytic cells.	PTGER2 TNF	4.34e-05	3	133	2	30053598
Pubmed	RIPK1 and TRADD Regulate TNF-Induced Signaling and Ripoptosome Formation.	RIPK1 TNF	4.34e-05	3	133	2	34830347
Pubmed	RIP1 protein-dependent assembly of a cytosolic cell death complex is required for inhibitor of apoptosis (IAP) inhibitor-mediated sensitization to lexatumumab-induced apoptosis.	RIPK1 TNF	4.34e-05	3	133	2	22927431
Pubmed	PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment.	P2RX7 PML	4.34e-05	3	133	2	36450825
Pubmed	Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production.	RIPK1 TNF	4.34e-05	3	133	2	25575821
Pubmed	The role of the kinases RIP1 and RIP3 in TNF-induced necrosis.	RIPK1 TNF	4.34e-05	3	133	2	20354226
Pubmed	The combination of TPL2 knockdown and TNFα causes synthetic lethality via caspase-8 activation in human carcinoma cell lines.	RIPK1 TNF	4.34e-05	3	133	2	31239343
Pubmed	Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5.	SMURF1 TNF	4.34e-05	3	133	2	27133717
Pubmed	ALPK1 phosphorylates myosin IIA modulating TNF-α trafficking in gout flares.	MYH9 TNF	4.34e-05	3	133	2	27169898
Pubmed	Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis.	RIPK1 TNF	8.67e-05	4	133	2	22028622
Pubmed	RIP3 induces apoptosis independent of pronecrotic kinase activity.	RIPK1 TNF	8.67e-05	4	133	2	25459880
Pubmed	Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.	RIPK1 TNF	8.67e-05	4	133	2	22265413
Pubmed	Long non-coding RNA ARHGAP5-AS1 inhibits migration of breast cancer cell via stabilizing SMAD7 protein.	SMURF1 SMURF2	8.67e-05	4	133	2	34370213
Pubmed	Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis.	RIPK1 TNF	8.67e-05	4	133	2	24434512
Pubmed	RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition.	RIPK1 TNF	8.67e-05	4	133	2	24821786
Pubmed	The death domain kinase RIP protects thymocytes from tumor necrosis factor receptor type 2-induced cell death.	RIPK1 TNF	8.67e-05	4	133	2	12093867
Pubmed	E3-14.7K is recruited to TNF-receptor 1 and blocks TNF cytolysis independent from interaction with optineurin.	RIPK1 TNF	8.67e-05	4	133	2	22675546
Pubmed	Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis.	RIPK1 TNF	8.67e-05	4	133	2	10521396
Pubmed	Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.	DUX4L2 DUX4L4	8.67e-05	4	133	2	17911620
Pubmed	The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis.	RIPK1 TNF	8.67e-05	4	133	2	22817896
Pubmed	Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria.	MYH9 ITGA2B	8.67e-05	4	133	2	29195076
Pubmed	Prostaglandin E2 differentially modulates proinflammatory/prodestructive effects of TNF-alpha on synovial fibroblasts via specific E prostanoid receptors/cAMP.	PTGER2 TNF	8.67e-05	4	133	2	19542367
Pubmed	Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1.	RIPK1 TNF	8.67e-05	4	133	2	35842423
Pubmed	Nedd8 targets ubiquitin ligase Smurf2 for neddylation and promote its degradation.	SMURF1 SMURF2	8.67e-05	4	133	2	27086113
Pubmed	The homeobox transcription factor DUXBL controls exit from totipotency.	DUX4L2 DUX4L4	8.67e-05	4	133	2	38509386
Pubmed	TNFα induced noncanonical NF-κB activation is attenuated by RIP1 through stabilization of TRAF2.	RIPK1 TNF	8.67e-05	4	133	2	21266470
Pubmed	The tumor suppressor Lgl1 forms discrete complexes with NMII-A and Par6α-aPKCζ that are affected by Lgl1 phosphorylation.	MYH9 LLGL1	8.67e-05	4	133	2	24213535
Pubmed	TNF-alpha induces two distinct caspase-8 activation pathways.	RIPK1 TNF	8.67e-05	4	133	2	18485876
Pubmed	IKK1/2 protect human cells from TNF-mediated RIPK1-dependent apoptosis in an NF-κB-independent manner.	RIPK1 TNF	8.67e-05	4	133	2	29630899
Pubmed	Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis.	SMURF1 SMURF2	8.67e-05	4	133	2	30566427
Pubmed	Tumor necrosis factor-α enhances the transcription of Smad ubiquitination regulatory factor 1 in an activating protein-1- and Runx2-dependent manner.	SMURF1 TNF	8.67e-05	4	133	2	23042144
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10	8.67e-05	4	133	2	7983737
Pubmed	Up-regulated renal expression of TNF-alpha signalling adapter proteins in lupus glomerulonephritis.	RIPK1 TNF	8.67e-05	4	133	2	19151112
Pubmed	Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.	GPR179 TRPM1	8.67e-05	4	133	2	22896717
Pubmed	The WW1 Domain Enhances Autoinhibition in Smurf Ubiquitin Ligases.	SMURF1 SMURF2	8.67e-05	4	133	2	31628949
Pubmed	LRIT3 is Required for Nyctalopin Expression and Normal ON and OFF Pathway Signaling in the Retina.	GPR179 TRPM1	1.44e-04	5	133	2	31959619
Pubmed	Differential associations between the cytoplasmic regions of the interleukin-12 receptor subunits beta1 and beta2 and JAK kinases.	IL12RB2 TYK2	1.44e-04	5	133	2	9038232
Pubmed	Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists.	PTGER2 TNF	1.44e-04	5	133	2	11301049
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7	1.44e-04	5	133	2	12629516
Pubmed	RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis.	RIPK1 TNF	1.44e-04	5	133	2	22173242
Pubmed	Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.	SMURF1 SMURF2	1.44e-04	5	133	2	20937913
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	1.44e-04	5	133	2	11401426
Pubmed	ABIN3 Negatively Regulates Necroptosis-induced Intestinal Inflammation Through Recruiting A20 and Restricting the Ubiquitination of RIPK3 in Inflammatory Bowel Disease.	RIPK1 TNF	1.44e-04	5	133	2	32599618
Pubmed	The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62.	RIPK1 TNF	1.44e-04	5	133	2	32354117
Pubmed	NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.	SMURF1 SMURF2	1.44e-04	5	133	2	28798345
Pubmed	MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation.	RIPK1 TNF	1.44e-04	5	133	2	28666573
Pubmed	Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation.	RIPK1 TNF	1.44e-04	5	133	2	23459942
Pubmed	Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α.	RIPK1 TNF	1.44e-04	5	133	2	24113711
Pubmed	The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.	RIPK1 TNF	1.44e-04	5	133	2	15175328
Pubmed	The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation.	RIPK1 TNF	1.44e-04	5	133	2	7758105
Pubmed	Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.	DUX4L2 DUX4L4	1.44e-04	5	133	2	20063414
Pubmed	NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling.	RIPK1 TNF	1.44e-04	5	133	2	21458669
Pubmed	RNA transcripts, miRNA-sized fragments and proteins produced from D4Z4 units: new candidates for the pathophysiology of facioscapulohumeral dystrophy.	DUX4L2 DUX4	1.44e-04	5	133	2	19359275
Pubmed	Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins.	SMURF1 TNF	1.44e-04	5	133	2	18567580
Cytoband	4q35.2	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.55e-10	27	134	6	4q35.2
Cytoband	Ensembl 112 genes in cytogenetic band chr4q35	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	5.85e-08	117	134	7	chr4q35
GeneFamily	PRD class homeoboxes and pseudogenes	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	3.52e-06	92	81	6	521
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CD55 APOH CSMD2 SNED1 SEZ6	5.56e-06	57	81	5	1179
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	MAG LRFN3 ROR2 LINGO1 PXDNL MYPN	8.49e-05	161	81	6	593
Coexpression	HARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_UP	IL12RB2 ENDOD1 ADAM19 KLF6 NR4A3 PTGER2 FANCA MST1R CSRNP1 NEURL3 P2RX7 AP5B1 NCOA7 TNF CCL19 VWA5B1 PML	4.84e-06	973	127	17	M41080
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS12 NR4A3 ADAMTS13 GFRA2 CSRNP1 NELL2 LINGO1	6.03e-07	176	123	7	a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRSS12 ROR2 SOSTDC1 PTGER2 SNED1 PXDNL PAK3	1.04e-06	191	123	7	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYH9 KLF6 SYNM CD55 ARHGAP9 PTGER2 CSRNP1	1.37e-06	199	123	7	c3c73c9404a73133bfad1f9ced292f5e508ef767
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	POLD1 ROR2 NR4A3 NELL2 SCUBE3 CCL19	7.85e-06	170	123	6	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS12 NR4A3 ADAMTS13 GFRA2 NELL2 LINGO1	9.27e-06	175	123	6	c227fc5d1ccb69b82a96a6354913cafaf27d0eec
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAM19 PRSS12 LINC00299 COMTD1 SSPOP PAK3	1.16e-05	182	123	6	dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAM19 PRSS12 LINC00299 COMTD1 SSPOP PAK3	1.16e-05	182	123	6	52274af3136d4fd4a495f5882618444661421f0f
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAM19 NRAP SYNM NR4A3 PXDNL MYPN	1.19e-05	183	123	6	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPTLC3 PRSS12 ROR2 SOSTDC1 SNED1 PAK3	1.19e-05	183	123	6	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC3 KLF6 CD55 NR4A3 CSRNP1 NCOA7	1.62e-05	193	123	6	ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCell	distal-Hematologic-Myeloid_Dendritic_Type_1-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAM19 NPIPB11 NR4A3 NEURL3 LINGO1 CCL19	1.66e-05	194	123	6	f0467d81063a9b19783906c456935ef8318b9b98
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	MYH9 ADAM19 NRAP ROR2 PXDNL MYPN	1.66e-05	194	123	6	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	(2)_NK/T-(220)_CD8+_Cytotoxic_T_cell\|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)	ROR2 PLXND1 ATG2A PTGER2 GTF3C1 TNF	1.76e-05	196	123	6	d123361c32bcd2329200f0316bc5b54bb494e92d
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-SEP / Disease, condition lineage and cell class	IL12RB2 KATNAL1 ITGA2B SCUBE3 PAK3 ZNF74	1.81e-05	197	123	6	c187e3fc2160b0165eb039cf09a6e621016068b7
ToppCell	LAM-Endothelial-LymEndo\|Endothelial / Condition, Lineage and Cell class	ENDOD1 ADAM19 KLF6 SYNM CD55 IPO11	1.87e-05	198	123	6	ba64b1c95dfaa995045239d412e725596f6c482e
ToppCell	Parenchymal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DIP2B LRFN3 ROR2 SKIDA1 CSMD2 KIAA1755	1.87e-05	198	123	6	0cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCell	Parenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DIP2B LRFN3 ROR2 SKIDA1 CSMD2 KIAA1755	1.87e-05	198	123	6	e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYH9 KLF6 SYNM CD55 PTGER2 CSRNP1	1.92e-05	199	123	6	f3cc3cda38f78d1d12d865df339d93c5fecf19f2
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-mDC\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NR4A3 ADAMTS13 CSRNP1 PAK3 TNF CCL19	1.97e-05	200	123	6	f78968d4b4d907094b2c44dcf5ac557ae94e4484
ToppCell	LA-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MYH9 ADAM19 NRAP MYPN TEDC1	4.22e-05	139	123	5	9e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
Disease	protein fam107a measurement	NLRP12 APOH	1.65e-04	5	121	2	EFO_0020673
Disease	neuroblastoma (implicated_via_orthology)	CD55 LLGL1	1.65e-04	5	121	2	DOID:769 (implicated_via_orthology)
Disease	Plasmodium falciparum malaria (is_marker_for)	ADAMTS13 TNF	1.65e-04	5	121	2	DOID:14067 (is_marker_for)
Disease	thrombocytopenia (is_implicated_in)	MYH9 ITGA2B TNF	1.83e-04	27	121	3	DOID:1588 (is_implicated_in)
Disease	plastin-2 measurement	NLRP12 APOH	2.47e-04	6	121	2	EFO_0801885
Disease	arachidonate 15-lipoxygenase B measurement	NLRP12 ALOX15B	3.46e-04	7	121	2	EFO_0801391
Disease	osteocalcin measurement	SPTLC3 NLRP12	3.46e-04	7	121	2	EFO_0010232
Disease	Adenocarcinoma of large intestine	RIPK1 ROR2 TYK2 PAK3	6.68e-04	96	121	4	C1319315
Disease	disseminated intravascular coagulation (is_marker_for)	ADAMTS13 TNF	7.35e-04	10	121	2	DOID:11247 (is_marker_for)
Disease	monocyte percentage of leukocytes	NLRP12 KLF6 LINC00299 ARHGAP9 TERT DDB2 GFRA2 FANCA SCUBE3 KIAA1755	8.78e-04	731	121	10	EFO_0007989
Disease	psoriasis	IL12RB2 ADAM19 TYK2 GMNC AP5B1 MYPN	9.39e-04	273	121	6	EFO_0000676
Disease	Schizophrenia	MAG APOH CSMD2 KCNH6 PPP3CC ERVK-8 SLC6A5 ZNF74 TNF TRPM1 PML	1.04e-03	883	121	11	C0036341
Disease	Night blindness, congenital stationary, type 1	GPR179 TRPM1	1.07e-03	12	121	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	GPR179 TRPM1	1.07e-03	12	121	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	GPR179 TRPM1	1.07e-03	12	121	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	GPR179 TRPM1	1.07e-03	12	121	2	C1850362
Disease	X-Linked Csnb	GPR179 TRPM1	1.07e-03	12	121	2	C3711543
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	GPR179 TRPM1	1.07e-03	12	121	2	C1848172
Disease	cognitive inhibition measurement	GFRA2 MICALL2 PXDNL	1.15e-03	50	121	3	EFO_0007969
Disease	Cone-rod synaptic disorder, congenital nonprogressive	GPR179 TRPM1	1.26e-03	13	121	2	C4041558
Disease	silicosis (biomarker_via_orthology)	TERT TNF	1.47e-03	14	121	2	DOID:10325 (biomarker_via_orthology)
Disease	systemic lupus erythematosus, COVID-19	IL12RB2 ARHGAP9 TYK2	1.76e-03	58	121	3	MONDO_0007915, MONDO_0100096
Disease	HbA1c measurement	DIP2B MYH9 CD55 BAZ1B LINC00299 ADAMTS13 LINGO1 MYPN SEZ6	1.90e-03	675	121	9	EFO_0004541
Disease	Night blindness, congenital stationary	GPR179 TRPM1	2.18e-03	17	121	2	C0339535
Disease	transient cerebral ischemia (implicated_via_orthology)	PLXND1 TERT TNF	2.34e-03	64	121	3	DOID:224 (implicated_via_orthology)
Disease	rheumatoid arthritis, COVID-19	TYK2 TNF CCL19	2.34e-03	64	121	3	EFO_0000685, MONDO_0100096
Disease	Bladder Neoplasm	TERT FANCA PPP3CC TNF	2.69e-03	140	121	4	C0005695
Disease	skin sensitivity to sun	KATNAL1 FANCA	2.72e-03	19	121	2	EFO_0004795
Disease	Malignant neoplasm of urinary bladder	TERT FANCA PPP3CC TNF	2.76e-03	141	121	4	C0005684
Disease	myelodysplastic syndrome (is_marker_for)	TERT TNF	3.02e-03	20	121	2	DOID:0050908 (is_marker_for)
Disease	Adenocarcinoma of prostate	KLF6 FANCA	3.02e-03	20	121	2	C0007112
Disease	freckles	LINC00299 FANCA	3.02e-03	20	121	2	EFO_0003963
Disease	interleukin-2 receptor subunit alpha measurement	KLF6 SLC6A5	3.33e-03	21	121	2	EFO_0010587
Disease	Headache, HbA1c measurement	PLXND1 PML	3.33e-03	21	121	2	EFO_0004541, HP_0002315
Disease	ectonucleoside triphosphate diphosphohydrolase 5 measurement	APOH LIN52	3.33e-03	21	121	2	EFO_0008115

Protein segments in the cluster

Peptide	Gene	Start	Entry
GSPRDWKCFLAVPDP	LINC00299	21	Q6ZSB3
ALDDVAVRPGPCWAP	MAMDC4	796	Q6UXC1
DDVAALRWPGPSQQP	CCDC187	56	A0A096LP49
EEGKWSPELPVCAPI	APOH	126	P02749
PEIECLPVPGALAQW	CSMD2	1771	Q7Z408
QQLWGPGARPAPDLC	ADAM19	526	Q9H013
QVCIPWLEGRGLPPL	ALG1L2	126	C9J202
ALQEPAPWSALPCGL	DUX4L4	356	P0CJ87
PALYEVPDGEWQCPA	BAZ1B	1216	Q9UIG0
ARTLAPPELWACPIQ	ARHGEF5	116	Q12774
CEALGPGPEFWLLPR	AJAP1	41	Q9UKB5
ARTLAPPELWACPIQ	ARHGEF35	116	A5YM69
LVLGVAPDDWPAPRA	ARMC5	596	Q96C12
WRVCEGPKAVAAPRP	CSDE1	736	O75534
GKGEPPWLCRLQLEP	LINC00469	26	Q8N7U9
ACAADPWEAPTPRIE	LINC00313	46	P59037
EPAPWSALPCGLLLD	DUX4L6	361	P0CJ89
AALRRACEDPPAPWE	CENPP	16	Q6IPU0
DLRPEPDPWAGQAVR	ATG2A	651	Q2TAZ0
GSQQPPAWPEACVLE	ADAMTS13	726	Q76LX8
LAAIDLAGPRPVPWA	C17orf113	341	A0A1B0GUU1
ELLEVAAAPAPEWCP	RASSF7	351	Q02833
LPWPAGFQPRVLVQC	LLGL1	581	Q15334
ARVLPERPGQWACPA	CAPN15	406	O75808
CPGKLPEGIPEQWAR	PAK3	101	O75914
GAPCLRWAEVPPFLE	PRSS12	106	P56730
RASPDLWPEQLPGVA	LIN52	26	Q52LA3
VPDNCPELRPELSWL	MAG	161	P20916
EPAPWSALPCGLLLD	DUX4	361	Q9UBX2
QGEVDCWPLPCPDVE	NELL2	726	Q99435
NAWCPGALPDPEIVR	NRAP	131	Q86VF7
PPFLECQEGRLRPGW	GPR179	231	Q6PRD1
WDQMPLPDRDFCGPR	CSRNP1	51	Q96S65
PCLPSPDIWNVDGAN	GTSF1L	96	Q9H1H1
PQVVNALCQAWGPLP	KIAA1755	191	Q5JYT7
RVEEPLEGVGPWQCP	FLYWCH1	211	Q4VC44
RGRQLCAPPDQPWVE	CCL19	66	Q99731
CAPPDQPWVERIIQR	CCL19	71	Q99731
VARLDCPRQWPELIP	IPO11	116	Q9UI26
ALRPQWCSREIPDPA	IL12RB2	656	Q99665
PQEDPDCWPLKLGSR	KCNH6	811	Q9H252
AVWGDCGLPPDVPNA	CD55	31	P08174
EPAPWSALPCGLLLD	DUX4L3	361	P0CJ86
PAPGGAEQRWLVEPQ	ENDOD1	86	O94919
ASLDVCDNWLRPEPP	MICALL2	671	Q8IY33
CDNWLRPEPPGQEAR	MICALL2	676	Q8IY33
PLLGEWKIPESCRPN	PLXND1	1391	Q9Y4D7
EDCETRQWLPPGESP	PTGER2	11	P43116
GEPLGVICNWPPALE	DIP2B	326	Q9P265
EAGVNPRGLCPNALW	HERVK_113	636	P63132
CRADGDPPPAILWLS	LINGO1	446	Q96FE5
AEQTGICKVRPPPDW	KDM5B	56	Q9UGL1
PPGILALLDEECWFP	MYH9	521	P35579
VVQLDCEPWGPGHEP	LRFN3	611	Q9BTN0
DVRSALLDPDWVCPP	CDCA7L	391	Q96GN5
CVLSFPENWPLGPEG	AP5B1	371	Q2VPB7
PEGAESRVWCPLGPQ	AP5B1	791	Q2VPB7
SVEAQPPWLPGLEAR	ARSA	186	P15289
EPRAPQPDPCAAWLD	NKX2-8	31	O15522
IPVLGPAPRWCSFLD	NOL10	341	Q9BSC4
DCLWVGLAGPQILPP	DDB2	51	Q92466
FPPCEDPARGWLSAN	MDS2	101	Q8NDY4
EAGVNPRGLCPNALW	ERVK-7	636	P63135
EAGVNPRGLCPNALW	ERVK-6	636	Q9BXR3
PCPLRDPEGLQQWLE	MAB21L3	101	Q8N8X9
CGERLWVPLPPSADD	NPIPB11	881	E5RHQ5
AWCPIEAVEEAPRPA	P2RX7	166	Q99572
VEWLCEADGNPPPVI	PXDNL	436	A1KZ92
RPLIWAAVREGCPGP	FCSK	571	Q8N0W3
PGPGQWVVAECPARV	FCSK	701	Q8N0W3
LQGPELHGWRPPVDC	GFRA2	26	O00451
VAPPERQGPWAALFV	FANCA	736	O15360
DAQPPELGRPLWRQA	COMTD1	136	Q86VU5
QPAPRCGEWTYNPLE	IGFL4	31	Q6B9Z1
AACNDVDRWPAPVPG	DENND6A	206	Q8IWF6
EPAPWSALPCGLLLD	DUX4L7	361	P0CJ90
PPIGVFWDIENCSVP	MARF1	351	Q9Y4F3
PWDELLGVLPPSLCA	LSMEM2	71	Q8N112
EPAPWSALPCGLLLD	DUX4L5	361	P0CJ88
AGVECIWNINPPPKR	SCUBE3	826	Q8IX30
PCLPRQYWEELGAPE	POLRMT	546	O00411
ADGQVPPSAIDPRWL	POLD1	66	P28340
LPLLGPLAPDAWFCR	ALOX15B	76	O15296
WDEALPSAPGCIAPG	NR4A3	156	Q92570
VSCQDEPFRDPAVWP	KATNAL1	86	Q9BW62
GLLWDPEGQCVPPSL	SSPOP	866	A2VEC9
ALRPPDGPGWDCALL	TMEM200B	156	Q69YZ2
VGCAEPEIWDPSPRR	TMEM200B	181	Q69YZ2
EVIFLGPAPACPEAW	SYNM	1186	O15061
ERLKLVCSPQPDWGP	SLC6A5	746	Q9Y345
NCEEQAGPPVDPWVL	GMNC	176	A6NCL1
DLPQDLCPLYRPGEW	NCOA7	296	Q8NI08
CQAPWPLGADTPALD	PML	91	P29590
NFPRRVLPCIPSEEW	FAF2	406	Q96CS3
PCPPSLIIGRDGDLW	SKIDA1	851	Q1XH10
ELEWPIQCPGAGLPV	PROZ	266	P22891
WNRPICSAPGPLFDL	SPTLC3	126	Q9NUV7
RNRQVLPCPDDCPAW	ROR2	706	Q01974
LGPCAAPPAWALNLD	ITGA2B	21	P08514
LCWEANPEARPTFPG	RIPK1	266	Q13546
IECDVLLEPNTPWGP	SANBR	516	Q6NSI8
NCDELGPLPPGWEVR	SMURF1	301	Q9HCE7
PHGVWSEPPQCLEID	SNED1	741	Q8TER0
ILEPPGRCCWNEPVR	ACOT4	6	Q8N9L9
REGIVAPLPGEWKPC	CEP164	51	Q9UPV0
FCWIARAPPLGNPLR	LINC01559	81	Q495D7
INCEELGPLPPGWEI	SMURF2	291	Q9HAU4
EPPAFGPVCDLLWSD	PPP3CC	216	P48454
RPGEQSEAWLAPQAP	ZSCAN32	171	Q9NX65
VNPVLLSGPEAPWRD	MINPP1	56	Q9UNW1
APWRDPELLEGTCTP	MINPP1	66	Q9UNW1
SCEPIRREGPKWDPA	DNTTIP1	191	Q9H147
VCEQPGLLPGDWAAP	TEDC1	266	Q86SX3
EAGVNPRGLCPNALW	ERVK-10	636	P10266
EAGVNPRGLCPNALW	ERVK-8	636	P63133
EVWLAELQGPCPQAP	ZNF395	121	Q9H8N7
EAGVNPRGLCPNALW	ERVK-11	636	Q9UQG0
RNDTCPELPEIPNGW	SEZ6	706	Q53EL9
ELRVWPPGAQEPCTV	NAPRT	451	Q6XQN6
PGPACPLLQRLDAWE	ARHGAP9	206	Q9BRR9
AGECLPLPVLPNWIG	SOSTDC1	101	Q6X4U4
RWQIEAVAPAQGPPA	NEURL3	241	Q96EH8
EDRPALQEPPWSLGC	ZNF333	126	Q96JL9
DEEGKRLPPCIPGAW	TRPM1	1036	Q7Z4N2
WEPGAAPAQQPRCLI	ZXDA	191	P98168
DKADPEGVWPCAAPI	WDR93	401	Q6P2C0
REVPRGPCPEWELKA	ZNF74	106	Q16587
LVGLPLLSPDAPCWE	TMEM204	121	Q9BSN7
REVLWPPQPGQREEC	SEMA3G	91	Q9NS98
PKSRPEPQWCEVQGL	ULBP1	41	Q9BZM6
PLPLEPCTQEFLWRA	GTF3C1	36	Q12789
LLPAKPAAGEDWQCP	MST1R	16	Q04912
VAQCLVCVPWDARPP	TERT	51	O14746
PCQRETPEGAEAKPW	TNF	176	P01375
PWCSVPRGALDGEAP	ZNF662	31	Q6ZS27
AVGQPADRPREPLWA	TYK2	361	P29597
LLPQGCQPFLPWGQE	VWA5B1	736	Q5TIE3
EPAPWSALPCGLLLD	DUX4L2	361	P0CJ85
REPSQLWGCVPGELP	KLF6	156	Q99612
CWPEPSAPLQELIRV	NLRP12	271	P59046
PPPQVRWYCEGKELE	MYPN	296	Q86TC9