Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH12 DNAH17 DNAH7	2.48e-05	18	64	3	GO:0008569
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH12 DNAH17 DNAH7	9.72e-05	28	64	3	GO:0051959
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH12 DNAH17 DNAH7	2.26e-04	37	64	3	GO:0045505
GeneOntologyCellularComponent	axonemal dynein complex	DNAH12 DNAH17 DNAH7	5.72e-05	25	63	3	GO:0005858
Domain	C_TYPE_LECTIN_1	MRC2 CLEC5A VCAN PKD1L2	1.53e-04	80	63	4	PS00615
Domain	Lectin_C	MRC2 CLEC5A VCAN PKD1L2	1.85e-04	84	63	4	PF00059
Domain	CLECT	MRC2 CLEC5A VCAN PKD1L2	1.85e-04	84	63	4	SM00034
Domain	C_TYPE_LECTIN_2	MRC2 CLEC5A VCAN PKD1L2	1.94e-04	85	63	4	PS50041
Domain	C-type_lectin-like	MRC2 CLEC5A VCAN PKD1L2	2.03e-04	86	63	4	IPR001304
Domain	-	MRC2 CLEC5A VCAN PKD1L2	3.22e-04	97	63	4	3.10.100.10
Domain	C-type_lectin-like/link	MRC2 CLEC5A VCAN PKD1L2	3.48e-04	99	63	4	IPR016186
Domain	CTDL_fold	MRC2 CLEC5A VCAN PKD1L2	4.68e-04	107	63	4	IPR016187
Domain	Ephrin_rec_like	SVEP1 EPHA7	6.04e-04	11	63	2	PF07699
Domain	MRGPCRFAMILY	MRGPRX1 MRGPRX3	6.04e-04	11	63	2	IPR026234
Domain	Sushi	VCAN C4BPA SVEP1	7.18e-04	52	63	3	PF00084
Domain	CCP	VCAN C4BPA SVEP1	8.03e-04	54	63	3	SM00032
Domain	SUSHI	VCAN C4BPA SVEP1	8.93e-04	56	63	3	PS50923
Domain	Sushi_SCR_CCP_dom	VCAN C4BPA SVEP1	9.40e-04	57	63	3	IPR000436
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH7	9.93e-04	14	63	2	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH7	9.93e-04	14	63	2	IPR013602
Domain	DHC_N2	DNAH12 DNAH7	9.93e-04	14	63	2	PF08393
Domain	AAA_8	DNAH12 DNAH7	9.93e-04	14	63	2	PF12780
Domain	DHC_fam	DNAH12 DNAH7	1.14e-03	15	63	2	IPR026983
Domain	Dynein_heavy_dom	DNAH12 DNAH7	1.14e-03	15	63	2	IPR004273
Domain	Dynein_heavy	DNAH12 DNAH7	1.14e-03	15	63	2	PF03028
Domain	JmjC	JMJD4 KDM7A	2.95e-03	24	63	2	PF02373
Domain	Ephrin_rec_like	SVEP1 EPHA7	3.20e-03	25	63	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	SVEP1 EPHA7	3.20e-03	25	63	2	IPR011641
Domain	JMJC	JMJD4 KDM7A	5.20e-03	32	63	2	PS51184
Domain	JmjC_dom	JMJD4 KDM7A	5.20e-03	32	63	2	IPR003347
Domain	JmjC	JMJD4 KDM7A	5.53e-03	33	63	2	SM00558
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	ERCC3 KLHDC2 ATG7 KDM7A HEATR1 AGBL5 PKD1L2	7.03e-07	272	64	7	18187620
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH12 DNAH17 DNAH7	2.13e-06	14	64	3	9373155
Pubmed	DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon.	PIEZO2 MRGPRX1 MRGPRX3	2.66e-06	15	64	3	37541195
Pubmed	Overexpression of protease-activated receptor-1 contributes to melanoma metastasis via regulation of connexin 43.	GJA1 F2R	3.33e-06	2	64	2	19679555
Pubmed	C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway.	PIEZO2 MRGPRX1 MRGPRX3	5.64e-06	19	64	3	38915692
Pubmed	Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation.	MRGPRX1 MRGPRX3	9.99e-06	3	64	2	28768771
Pubmed	The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms.	MRGPRX1 MRGPRX3	9.99e-06	3	64	2	26022362
Pubmed	Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways.	MRGPRX1 MRGPRX3	9.99e-06	3	64	2	27215903
Pubmed	Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs.	MRGPRX1 MRGPRX3	9.99e-06	3	64	2	11850634
Pubmed	A role for thrombin receptor signaling in endothelial cells during embryonic development.	F2R F5	9.99e-06	3	64	2	11533492
Pubmed	bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells.	MRGPRX1 MRGPRX3	9.99e-06	3	64	2	10662793
Pubmed	Agonists of the MAS-related gene (Mrgs) orphan receptors as novel mediators of mast cell-sensory nerve interactions.	MRGPRX1 MRGPRX3	9.99e-06	3	64	2	18250432
Pubmed	Mas-related G protein-coupled receptor C11 (Mrgprc11) induces visceral hypersensitivity in the mouse colon: A novel target in gut nociception?	MRGPRX1 MRGPRX3	9.99e-06	3	64	2	31119828
Pubmed	MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	29064954
Pubmed	Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	33727332
Pubmed	A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	10504302
Pubmed	A mechanically activated ion channel is functionally expressed in the MrgprB4 positive sensory neurons, which detect stroking of hairy skin in mice.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	28545921
Pubmed	Substance P activates Mas-related G protein-coupled receptors to induce itch.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	28219706
Pubmed	Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	35882236
Pubmed	Molecular Signature of Pruriceptive MrgprA3+ Neurons.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	32234460
Pubmed	Overlap of direct and indirect alloreactive T-cell repertoires when MHC polymorphism is limited to the peptide binding groove.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	11821156
Pubmed	Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	17975009
Pubmed	Human sensory neuron-specific Mas-related G protein-coupled receptors-X1 sensitize and directly activate transient receptor potential cation channel V1 via distinct signaling pathways.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	23074220
Pubmed	Characterization of new G protein-coupled adenine receptors in mouse and hamster.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	23608776
Pubmed	The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	21775281
Pubmed	Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	26874069
Pubmed	Tick peptides evoke itch by activating MrgprC11/MRGPRX1 to sensitize TRPV1 in pruriceptors.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	33358893
Pubmed	USP48 alleviates bone cancer pain and regulates MrgC stabilization in spinal cord neurons of male mice.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	36864656
Pubmed	Low maternal care enhances the skin barrier resistance of offspring in mice.	MRGPRX1 MRGPRX3	2.00e-05	4	64	2	31295326
Pubmed	Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.	GJA1 FZD5 VCAN	2.57e-05	31	64	3	30254141
Pubmed	Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability.	F2R F5	3.32e-05	5	64	2	19687358
Pubmed	Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.	MRGPRX1 MRGPRX3	3.32e-05	5	64	2	20004959
Pubmed	Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch.	MRGPRX1 MRGPRX3	3.32e-05	5	64	2	17618277
Pubmed	Microphthalmia resulting from MSX2-induced apoptosis in the optic vesicle.	GJA1 DCT	3.32e-05	5	64	2	12766037
Pubmed	Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling.	MRGPRX1 MRGPRX3	3.32e-05	5	64	2	20203048
Pubmed	Linkage map of nine loci defined by polymorphic DNA markers assigned to rat chromosome 13.	C4BPA F5	3.32e-05	5	64	2	8288230
Pubmed	COL3A1, CXCL8, VCAN, THBS2, and COL1A2 are correlated with the onset of biliary atresia.	THBS2 VCAN	3.32e-05	5	64	2	36930067
Pubmed	Regional Differences in Itch Transmission.	MRGPRX1 MRGPRX3	3.32e-05	5	64	2	38735364
Pubmed	MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations.	MRGPRX1 MRGPRX3	3.32e-05	5	64	2	34116733
Pubmed	Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+.	MRGPRX1 MRGPRX3	3.32e-05	5	64	2	22472648
Pubmed	Cross-sensitization of histamine-independent itch in mouse primary sensory neurons.	MRGPRX1 MRGPRX3	3.32e-05	5	64	2	23000623
Pubmed	A subpopulation of nociceptors specifically linked to itch.	MRGPRX1 MRGPRX3	4.98e-05	6	64	2	23263443
Pubmed	Visualizing the Itch-Sensing Skin Arbors.	MRGPRX1 MRGPRX3	4.98e-05	6	64	2	33091423
Pubmed	Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo.	MRGPRX1 MRGPRX3	4.98e-05	6	64	2	23364746
Pubmed	Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner.	GJA1 ATG7	4.98e-05	6	64	2	22496425
Pubmed	Identification of a bilirubin receptor that may mediate a component of cholestatic itch.	MRGPRX1 MRGPRX3	4.98e-05	6	64	2	30657454
Pubmed	Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain.	MRGPRX1 MRGPRX3	4.98e-05	6	64	2	24549959
Pubmed	Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.	MRGPRX1 MRGPRX3	4.98e-05	6	64	2	26216096
Pubmed	MrgprC11+ sensory neurons mediate glabrous skin itch.	MRGPRX1 MRGPRX3	4.98e-05	6	64	2	33876765
Pubmed	Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity.	MRGPRX1 MRGPRX3	6.96e-05	7	64	2	36693373
Pubmed	An airway-to-brain sensory pathway mediates influenza-induced sickness.	PIEZO2 PDYN	9.27e-05	8	64	2	36890237
Pubmed	Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes.	MRGPRX1 MRGPRX3	9.27e-05	8	64	2	24583173
Pubmed	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.	MRGPRX1 MRGPRX3	9.27e-05	8	64	2	12909716
Pubmed	Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population.	VCAN EPHA7	1.19e-04	9	64	2	25194280
Pubmed	Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway.	MRGPRX1 MRGPRX3	1.19e-04	9	64	2	12397184
Pubmed	Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types.	MRGPRX1 MRGPRX3	1.19e-04	9	64	2	30886406
Pubmed	Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens.	MRGPRX1 MRGPRX3	1.49e-04	10	64	2	33098765
Pubmed	Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches.	VCAN DCT	1.81e-04	11	64	2	22510689
Pubmed	A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.	MRGPRX1 MRGPRX3	1.81e-04	11	64	2	11551509
Pubmed	An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates.	MRGPRX1 MRGPRX3	1.81e-04	11	64	2	21151121
Pubmed	The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.	GJA1 DNAH12 MTMR3 C4BPA MAP3K4 SEC13	1.87e-04	453	64	6	27113764
Pubmed	The human plasma proteome: a nonredundant list developed by combination of four separate sources.	HPX C4BPA F5 EPHA7	2.49e-04	165	64	4	14718574
Pubmed	The gene map of the Norway rat (Rattus norvegicus) and comparative mapping with mouse and man.	APEH C4BPA F5	2.50e-04	66	64	3	1889815
Pubmed	Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth.	VCAN TCTN2	2.57e-04	13	64	2	32909945
Pubmed	PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.	GJA1 DCT	2.99e-04	14	64	2	24875170
Pubmed	Parallel ascending spinal pathways for affective touch and pain.	MRGPRX1 MRGPRX3	2.99e-04	14	64	2	33116307
Pubmed	A brain-to-spinal sensorimotor loop for repetitive self-grooming.	MRGPRX1 MRGPRX3	3.45e-04	15	64	2	34932943
Pubmed	Muscleblind-like 1 is required for normal heart valve development in vivo.	VCAN DCT	3.45e-04	15	64	2	26472242
Pubmed	Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies.	KLHDC2 TGS1	3.93e-04	16	64	2	12097419
Pubmed	High-resolution comparative mapping of mouse chromosome 17.	THBS2 MAP3K4	3.93e-04	16	64	2	8406442
Pubmed	Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors.	MRGPRX1 MRGPRX3	4.45e-04	17	64	2	25834056
Pubmed	p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling.	MRGPRX1 MRGPRX3	5.00e-04	18	64	2	29045838
Pubmed	An integrated genetic map of the pearl locus of mouse chromosome 13.	VCAN F2R	5.59e-04	19	64	2	8828042
Pubmed	Tlx3 and Runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors.	MRGPRX1 MRGPRX3	5.59e-04	19	64	2	22787056
Pubmed	Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor.	MRGPRX1 MRGPRX3	5.59e-04	19	64	2	24516396
Pubmed	Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli.	MRGPRX1 MRGPRX3	6.20e-04	20	64	2	35875660
Pubmed	ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.	MRGPRX1 MRGPRX3	6.84e-04	21	64	2	25369838
Pubmed	Report of the sixth international workshop on human chromosome 3 mapping 1995.	APEH SEC13	6.84e-04	21	64	2	8641130
Pubmed	Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1.	MRGPRX1 MRGPRX3	6.84e-04	21	64	2	28476948
Pubmed	Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation.	MRGPRX1 MRGPRX3	8.23e-04	23	64	2	20096094
Pubmed	Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.	MRGPRX1 MRGPRX3	8.23e-04	23	64	2	16446141
Pubmed	A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.	MRGPRX1 MRGPRX3	8.96e-04	24	64	2	17553423
Pubmed	Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease.	GJA1 VCAN	9.73e-04	25	64	2	26100917
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	THBS2 VCAN CAPG SVEP1	1.15e-03	248	64	4	24006456
Pubmed	Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling.	MRGPRX1 MRGPRX3	1.50e-03	31	64	2	21300867
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	ERCC3 ATG7 HEATR1 RMC1 PPAT	1.50e-03	454	64	5	33226137
Pubmed	Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.	GJA1 VCAN	1.60e-03	32	64	2	31434798
Pubmed	Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex.	ERCC3 SEC13	1.60e-03	32	64	2	19338310
Pubmed	KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.	ALDH18A1 EPHA7	1.70e-03	33	64	2	25582440
Pubmed	Early embryonic expression of murine coagulation system components.	F2R F5	1.80e-03	34	64	2	11154109
GeneFamily	Dyneins, axonemal	DNAH12 DNAH17 DNAH7	8.33e-06	17	43	3	536
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	VCAN C4BPA SVEP1	3.35e-04	57	43	3	1179
Coexpression	GAO_LARGE_INTESTINE_24W_C1_DCLK1POS_PROGENITOR	THBS2 PIEZO2 PDGFRL MRC2 VCAN SVEP1	1.56e-07	99	64	6	M39152
Coexpression	KANNAN_BLOOD_2012_2013_TIV_AGE_65PLS_REVACCINATED_IN_6_9_MO_VS_REVACCINATED_IN_12_13_MOS_DN	DCAF6 CAPG PHRF1 MTMR3 MCMDC2 RMC1 SEC13	1.99e-05	342	64	7	M41062
Coexpression	MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_INDEPENDENT	PDGFRL MRC2 VCAN	2.71e-05	24	64	3	M38986
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	THBS2 PIEZO2 PDGFRL MRC2 VCAN F2R SVEP1	1.25e-08	194	64	7	2260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CORO1A CSF2RB CLEC5A VCAN TMC8 F5	1.50e-07	167	64	6	1cd9e2af85c6c5b9e1d88991c87ac6980b387243
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 PDGFRL MRC2 VCAN F2R SVEP1	3.73e-07	195	64	6	18b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THBS2 PIEZO2 PDGFRL MRC2 VCAN SVEP1	3.73e-07	195	64	6	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THBS2 PIEZO2 PDGFRL MRC2 F2R SVEP1	3.85e-07	196	64	6	525d6c8a277364e624e7cc586275f8a891436b57
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 THBS2 PDGFRL NFIX F2R SVEP1	3.85e-07	196	64	6	61bee32ca299219f31a30b57124e44e85b798e9f
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 PIEZO2 PDGFRL MRC2 VCAN SVEP1	3.96e-07	197	64	6	2744cc94883c5d0424677cf5093bbab622933e9b
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	GJA1 THBS2 PIEZO2 PDGFRL MRC2 NFIX	4.08e-07	198	64	6	4f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 PIEZO2 PDGFRL NFIX VCAN SVEP1	4.20e-07	199	64	6	103f657132e830a0e5efeb745afb4b77c208a1fa
ToppCell	Fibroblasts-CD34+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	THBS2 PDGFRL MRC2 NFIX VCAN SVEP1	4.20e-07	199	64	6	13ff7409e200a0b46cdb7924d15ef33639693622
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS2 PDGFRL MRC2 NFIX VCAN SVEP1	4.33e-07	200	64	6	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	THBS2 PDGFRL MRC2 NFIX VCAN SVEP1	4.33e-07	200	64	6	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	THBS2 PDGFRL MRC2 NFIX VCAN SVEP1	4.33e-07	200	64	6	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	BLOOD--(3)_MNP-(3)_Classical_Mono-1\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CLEC5A VCAN CAPG MTMR3 F5	1.92e-06	142	64	5	395f80e99be4a0ef07fb9d65c74399e7e67c9a8d
ToppCell	facs-Lung-Endomucin-24m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO1A CSF2RB CLEC5A VCAN CAPG	2.76e-06	153	64	5	9c3220604b7fa4d91577b6c46960960f49644ca1
ToppCell	facs-Lung-Endomucin-24m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO1A CSF2RB CLEC5A VCAN CAPG	2.76e-06	153	64	5	ba624782693b0daa642e50881dbf5f0663fea82d
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RB CLEC5A VCAN CAPG F5	3.23e-06	158	64	5	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RB CLEC5A VCAN CAPG F5	3.23e-06	158	64	5	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CORO1A CSF2RB CLEC5A VCAN CAPG	4.36e-06	168	64	5	0ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CORO1A CSF2RB CLEC5A VCAN CAPG	4.36e-06	168	64	5	ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CSF2RB NFIX CLEC5A VCAN F5	4.49e-06	169	64	5	813472d429c0b12580b17b440e00a6d8beb7947f
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO2 PDGFRL MRC2 VCAN DNAH17	5.63e-06	177	64	5	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 MRC2 VCAN F2R SVEP1	6.11e-06	180	64	5	ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 INSYN1 MRC2 VCAN SVEP1	6.27e-06	181	64	5	269b39ac65790061d54eab47a8eeb024403f0348
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 INSYN1 MRC2 VCAN SVEP1	6.27e-06	181	64	5	cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 INSYN1 MRC2 VCAN SVEP1	6.27e-06	181	64	5	c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO2 PDGFRL MRC2 VCAN SVEP1	6.44e-06	182	64	5	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 THBS2 PIEZO2 INSYN1 MRC2	6.97e-06	185	64	5	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THBS2 MRC2 VCAN F2R SVEP1	6.97e-06	185	64	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 THBS2 PIEZO2 INSYN1 MRC2	6.97e-06	185	64	5	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 THBS2 PIEZO2 INSYN1 MRC2	6.97e-06	185	64	5	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THBS2 PDGFRL MRC2 F2R SVEP1	7.54e-06	188	64	5	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THBS2 PIEZO2 MRC2 VCAN SVEP1	7.94e-06	190	64	5	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PIEZO2 MRC2 VCAN SVEP1	7.94e-06	190	64	5	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THBS2 PIEZO2 MRC2 VCAN SVEP1	8.14e-06	191	64	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PIEZO2 MRC2 VCAN SVEP1	8.14e-06	191	64	5	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PIEZO2 MRC2 VCAN SVEP1	8.14e-06	191	64	5	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THBS2 PIEZO2 PDGFRL MRC2 SVEP1	8.35e-06	192	64	5	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PIEZO2 MRC2 VCAN SVEP1	8.35e-06	192	64	5	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDGFRL MRC2 VCAN SVEP1	8.35e-06	192	64	5	f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 MRC2 NFIX VCAN SVEP1	8.35e-06	192	64	5	f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDGFRL MRC2 VCAN SVEP1	8.35e-06	192	64	5	41a8326cd5bc19ad5041068501bab4c72399222e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THBS2 PIEZO2 PDGFRL MRC2 SVEP1	8.35e-06	192	64	5	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	THBS2 PIEZO2 PDGFRL MRC2 SVEP1	8.35e-06	192	64	5	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 MRC2 NFIX VCAN SVEP1	8.35e-06	192	64	5	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP47 GJA1 TMEM132D VCAN DNAH7	8.56e-06	193	64	5	ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSYN1 MRC2 NFIX VCAN SVEP1	8.56e-06	193	64	5	0a665531d581d4e3941e29d3f95569da8f166447
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 MRC2 VCAN F2R SVEP1	8.56e-06	193	64	5	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	PCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CORO1A CSF2RB CLEC5A PRSS21 TMC8	8.56e-06	193	64	5	888b11d7d66970931d1c33bea714659ca3cfe149
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH12 C4BPA PLA2G4F DNAH7	8.56e-06	193	64	5	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSYN1 MRC2 NFIX VCAN SVEP1	8.56e-06	193	64	5	24ce1f37cca655415410d2403a52d1ebb3332280
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 MRC2 VCAN F2R SVEP1	8.56e-06	193	64	5	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	PCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CORO1A CSF2RB CLEC5A PRSS21 TMC8	8.78e-06	194	64	5	6b48383151b678489bcd6133d389a5d8b3a50186
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THBS2 PIEZO2 PDGFRL MRC2 SVEP1	8.78e-06	194	64	5	439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDGFRL MRC2 VCAN SVEP1	8.78e-06	194	64	5	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDGFRL MRC2 VCAN SVEP1	8.78e-06	194	64	5	29f83cdd63314fff41258937d70b881a5503bfcc
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDGFRL MRC2 VCAN SVEP1	8.78e-06	194	64	5	d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA1 THBS2 PDGFRL NFIX SVEP1	8.78e-06	194	64	5	889c6e231bdd5b59902c7d2afdc077360b1d3256
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 THBS2 VCAN F2R SVEP1	9.00e-06	195	64	5	841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	THBS2 MRC2 VCAN F2R SVEP1	9.00e-06	195	64	5	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PDGFRL MRC2 VCAN SVEP1	9.00e-06	195	64	5	47762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 PDGFRL VCAN F2R SVEP1	9.00e-06	195	64	5	095b8e0be385b6390420589124a95fa4ba3682ab
ToppCell	-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CORO1A THBS2 PIEZO2 TMC8 SVEP1	9.00e-06	195	64	5	e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	THBS2 PDGFRL MRC2 VCAN SVEP1	9.23e-06	196	64	5	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 PDGFRL MRC2 NFIX VCAN	9.23e-06	196	64	5	59b5b5a0c123d0423abd19c312514849004b903b
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 MRC2 NFIX VCAN SVEP1	9.23e-06	196	64	5	cbfe01ba8071864e19b37028236ae35789f630fe
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 PDGFRL MRC2 F2R SVEP1	9.23e-06	196	64	5	fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCell	facs-Trachea\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA1 THBS2 NFIX VCAN CAPG	9.23e-06	196	64	5	8209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCell	facs-Trachea\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 THBS2 NFIX VCAN CAPG	9.23e-06	196	64	5	34020d6553309daa269dff05de0a8567211ea4d2
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 PDGFRL MRC2 NFIX VCAN	9.46e-06	197	64	5	b16add329bb35a558287ede51353010dde5bc029
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	THBS2 PIEZO2 MRC2 VCAN SVEP1	9.46e-06	197	64	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 PIEZO2 MRC2 VCAN SVEP1	9.46e-06	197	64	5	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	(2)_Fibroblasts-(23)_Fibro-4\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	THBS2 PDGFRL NFIX VCAN CAPG	9.46e-06	197	64	5	a183919023a4aca90a06be0e5e89c817b38c5574
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 MRC2 VCAN F2R SVEP1	9.46e-06	197	64	5	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	THBS2 PIEZO2 MRC2 VCAN SVEP1	9.46e-06	197	64	5	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	Mesenchymal_cells-Arteriolar_fibro.\|Mesenchymal_cells / Lineage and Cell class	THBS2 PIEZO2 PDGFRL NFIX CAPG	9.46e-06	197	64	5	cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCell	10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CORO1A CLEC5A VCAN CAPG KDM7A	9.69e-06	198	64	5	c7c5865395992131d0766a03c9c63bad9196b02f
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THBS2 PIEZO2 MRC2 VCAN SVEP1	9.69e-06	198	64	5	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	15-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	THBS2 PIEZO2 PDGFRL MRC2 VCAN	9.69e-06	198	64	5	3d76393e72eed59b4dd16130ef5dd1d331ba5711
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	THBS2 PIEZO2 MRC2 VCAN SVEP1	9.69e-06	198	64	5	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THBS2 PIEZO2 MRC2 VCAN SVEP1	9.69e-06	198	64	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	THBS2 PDGFRL MRC2 NFIX VCAN	9.93e-06	199	64	5	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 MRC2 NFIX VCAN SVEP1	9.93e-06	199	64	5	8d71e1fc92ee24deedf23fbb1a85a7fba0d8d436
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 PIEZO2 PDGFRL MRC2 SVEP1	9.93e-06	199	64	5	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	THBS2 PIEZO2 PDGFRL MRC2 VCAN	1.02e-05	200	64	5	e663995fc44c340d878d66b278b7b5c2ff784301
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THBS2 PIEZO2 PDGFRL MRC2 SVEP1	1.02e-05	200	64	5	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	THBS2 PIEZO2 PDGFRL MRC2 NFIX	1.02e-05	200	64	5	c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS2 PIEZO2 PDGFRL MRC2 VCAN	1.02e-05	200	64	5	4dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS2 PIEZO2 PDGFRL MRC2 NFIX	1.02e-05	200	64	5	137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-4\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	THBS2 PIEZO2 PDGFRL MRC2 VCAN	1.02e-05	200	64	5	bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCell	LPS_only-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|LPS_only / Treatment groups by lineage, cell group, cell type	CORO1A CSF2RB CLEC5A VCAN CAPG	1.02e-05	200	64	5	3504aeba7b30cac9c428ba3871c072e2202752b4
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THBS2 PIEZO2 PDGFRL MRC2 SVEP1	1.02e-05	200	64	5	2e4ab7fbd94d3d865ef6188d3b4916d2bf1b8d89
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 PIEZO2 PDGFRL MRC2 SVEP1	1.02e-05	200	64	5	6e3d1ae0ef84d3075afa40129a41169996462672
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THBS2 PDGFRL MRC2 VCAN SVEP1	1.02e-05	200	64	5	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	THBS2 PIEZO2 PDGFRL MRC2 VCAN	1.02e-05	200	64	5	8256511b099c3eab8e33194f90c9ff354e7cfe8e
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS2 PIEZO2 PDGFRL MRC2 VCAN	1.02e-05	200	64	5	2cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCell	LPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CORO1A CSF2RB CLEC5A VCAN CAPG	1.02e-05	200	64	5	fd1b6db3c62f5a205b769ba0e61433dae6285b67
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 PIEZO2 MRC2 VCAN SVEP1	1.02e-05	200	64	5	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	THBS2 PIEZO2 PDGFRL MRC2 VCAN	1.02e-05	200	64	5	8cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 PDGFRL MRC2 VCAN SVEP1	1.02e-05	200	64	5	74ad0ae592252060ee294d7483327d765a6ba1dd
Computational	ECM and collagens.	GJA1 THBS2 PDGFRL MRC2 VCAN F2R	1.44e-04	225	39	6	MODULE_47
Disease	anemia (phenotype), response to ribavirin	DNAH17 PHRF1	1.50e-04	9	61	2	EFO_0004272, GO_1901559
Disease	pulmonary embolism	TMEM132D DNAH17	1.22e-03	25	61	2	EFO_0003827
Disease	brain ischemia (biomarker_via_orthology)	GJA1 CSF2RB F2R	1.25e-03	102	61	3	DOID:2316 (biomarker_via_orthology)
Disease	inflammatory biomarker measurement	PIEZO2 F5	1.32e-03	26	61	2	EFO_0004872
Disease	factor XI measurement, venous thromboembolism	C4BPA F5	1.76e-03	30	61	2	EFO_0004286, EFO_0004694

Protein segments in the cluster

Peptide	Gene	Start	Entry
DCAETEFENGNRSWF	AGBL5	61	Q8NDL9
ETSRFSAICQGDGTW	C4BPA	401	P04003
DSFFSAGEDCVVIIW	VCAN	3256	P13611
EDVRVSQTTWDSGFC	CORO1A	26	P31146
TFLSCGEDGTVRWFD	DCAF6	156	Q58WW2
ELWDTSGQGRFCTIF	RAB40C	66	Q96S21
LSDSWEFCSFLDVST	INSYN1	106	Q2T9L4
SFQELSACVFSWIEE	MLX	261	Q9UH92
FCRWTQGFVFSESEG	MINDY3	26	Q9H8M7
WVAFQSDGTVTSCDS	PASK	241	Q96RG2
SWSSSVTQSEVFFGD	KDM7A	316	Q6ZMT4
SFQDCFVTSGVWNVT	NFIX	211	Q14938
CSFWSFVDVDSSSRR	MCMDC2	456	Q4G0Z9
ESSCQGFAWATDLST	EDRF1	786	Q3B7T1
SCFIRTDQLDGETDW	ATP9B	261	O43861
SEEWERCQSFLSFFT	PDYN	56	P01213
EDFTSETCNSSFRLW	DNAH12	2571	Q6ZR08
WDEEDGASCSTFFGS	PHRF1	941	Q9P1Y6
TYVDVDGAWRTTSCD	MRC2	1221	Q9UBG0
SGANSVWCETSDFIT	MRGPRX3	166	Q96LB0
VRTNLSGEDFAEWCE	PLA2G4F	501	Q68DD2
DFTTFCSVGEWLQAI	EPHA7	921	Q15375
SACVFWNASTRFSDG	ALDH18A1	716	P54886
SSEWVTSDCAQTFAF	PKD1L2	136	Q7Z442
GEFTVFAECTTSEWH	PKD1L2	316	Q7Z442
SDWQFGSELCRFVTA	F2R	166	P25116
DIWGEIDTRFSFCAV	RABGGTB	136	P53611
GSFSEEQFWEACAEL	PCTP	6	Q9UKL6
SFSADERTFATFWIG	FZD5	226	Q13467
FFDGAAVLSCSWEVR	CSF2RB	251	P32927
WSSSFQSVEVVCFRD	ATG7	256	O95352
QTGAWGCFDEFNRIS	DNAH17	1891	Q9UFH2
ADIFRSFSWSVNVCG	JMJD4	236	Q9H9V9
VESAWGDEQSAFRCN	GJA1	41	P17302
FSLIWSVGASCTDDD	DNAH7	1851	Q8WXX0
VLGTFEFDETSFWNS	KLHDC2	171	Q9Y2U9
VSVDVGEDASFSCAW	KIRREL2	321	Q6UWL6
TERALNWDSFNTGDC	CAPG	151	P40121
EADTEFWFSVCCEFS	HEATR1	1441	Q9H583
WSTIDDSQICRFTSD	ERCC3	381	P19447
SSLECEVTWQQGFSS	CFAP47	911	Q6ZTR5
SRCSTEIFSEASWEQ	MTMR3	1091	Q13615
LEFGLQESCAEFWTS	MAP3K4	766	Q9Y6R4
VTERCSDGWSFDATT	HPX	46	P02790
QDGRVFIWTCDDASS	SEC13	236	P55735
STIRSVESCWFFGDF	TAAR5	91	O14804
EAAISCWVQFSDGSV	TMEM132D	706	Q14C87
SITTLGFCFDDTVQW	F5	596	P12259
AERWESSFCDTVRLF	PTCHD1	226	Q96NR3
DEGFWDCSVCTFRNS	RYBP	21	Q8N488
SGADSAWCQTSDFIT	MRGPRX1	166	Q96LB2
VNSTSADTGEFSCWV	PDGFRL	131	Q15198
TDTDTFTCQKDGRWF	SVEP1	3156	Q4LDE5
LGCWSADSQRVVFDS	APEH	366	P13798
RCFFLSTSESSWNES	CLEC5A	81	Q9NY25
STSESSWNESRDFCK	CLEC5A	86	Q9NY25
VFSSWDFCIRVQEAA	TMC8	246	Q8IU68
FCWTSSTEIVFITDQ	RMC1	116	Q96DM3
NFDSEICGVVSDAVW	RMND5B	96	Q96G75
ETEGWVVSSESCSFL	PPAT	226	Q06203
CSTWEKTFRQIGFES	PIEZO2	96	Q9H5I5
NSRFSSWETVCDSLD	DCT	276	P40126
STFEFENRTDCWVTG	PRSS21	161	Q9Y6M0
FFAENETWVVDSCTT	THBS2	326	P35442
EAQGWTFDASQSCDT	TGS1	256	Q96RS0
GLDWCSSNETDSFSE	TCTN2	101	Q96GX1