Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	proteoglycan biosynthetic process	HS6ST2 HS3ST6 B3GAT1 CHPF2 CHST13	4.57e-06	70	72	5	GO:0030166
GeneOntologyBiologicalProcess	proteoglycan metabolic process	HS6ST2 HS3ST6 B3GAT1 CHPF2 CHST13	2.26e-05	97	72	5	GO:0006029
GeneOntologyBiologicalProcess	aminoglycan metabolic process	B3GNT9 STAB2 B3GAT1 CHPF2 CHST13	9.87e-05	132	72	5	GO:0006022
GeneOntologyBiologicalProcess	chondroitin sulfate proteoglycan biosynthetic process	B3GAT1 CHPF2 CHST13	1.00e-04	26	72	3	GO:0050650
GeneOntologyBiologicalProcess	negative regulation of myeloid cell differentiation	PTPN2 TOB2 LILRB2 TWIST2 CDC73	1.06e-04	134	72	5	GO:0045638
GeneOntologyBiologicalProcess	aminoglycan biosynthetic process	B3GNT9 B3GAT1 CHPF2 CHST13	1.77e-04	80	72	4	GO:0006023
GeneOntologyCellularComponent	Sec61 translocon complex	SEC61A2 SEC61A1	1.16e-04	5	72	2	GO:0005784
GeneOntologyCellularComponent	translocon complex	SEC61A2 SEC61A1	1.74e-04	6	72	2	GO:0071256
Domain	Plug_translocon	SEC61A2 SEC61A1	1.42e-05	2	71	2	PF10559
Domain	SecY_su_dom	SEC61A2 SEC61A1	1.42e-05	2	71	2	IPR023201
Domain	SecY	SEC61A2 SEC61A1	1.42e-05	2	71	2	PF00344
Domain	SECY_1	SEC61A2 SEC61A1	1.42e-05	2	71	2	PS00755
Domain	SECY_2	SEC61A2 SEC61A1	1.42e-05	2	71	2	PS00756
Domain	-	SEC61A2 SEC61A1	1.42e-05	2	71	2	1.10.3370.10
Domain	Translocon_Sec61/SecY_plug_dom	SEC61A2 SEC61A1	1.42e-05	2	71	2	IPR019561
Domain	SecY_CS	SEC61A2 SEC61A1	1.42e-05	2	71	2	IPR030659
Domain	Tob1/2	TOB2 TOB1	1.42e-05	2	71	2	IPR015676
Domain	SecY/SEC61-alpha	SEC61A2 SEC61A1	1.42e-05	2	71	2	IPR002208
Domain	BTG_2	TOB2 TOB1	2.12e-04	6	71	2	PS01203
Domain	BTG_1	TOB2 TOB1	2.12e-04	6	71	2	PS00960
Domain	Anti_prolifrtn	TOB2 TOB1	2.12e-04	6	71	2	IPR002087
Domain	btg1	TOB2 TOB1	2.12e-04	6	71	2	SM00099
Domain	BTG	TOB2 TOB1	2.12e-04	6	71	2	PF07742
Domain	Sulfotransfer_2	HS6ST2 CHST13	9.18e-04	12	71	2	PF03567
Domain	Sulfotransferase	HS6ST2 CHST13	9.18e-04	12	71	2	IPR005331
Domain	START	STARD9 ACOT12	1.45e-03	15	71	2	PF01852
Domain	START_lipid-bd_dom	STARD9 ACOT12	1.45e-03	15	71	2	IPR002913
Domain	START	STARD9 ACOT12	1.45e-03	15	71	2	PS50848
Domain	K_chnl_inward-rec_Kir_cyto	KCNJ9 KCNJ11	1.65e-03	16	71	2	IPR013518
Domain	IRK	KCNJ9 KCNJ11	1.65e-03	16	71	2	PF01007
Domain	-	KCNJ9 KCNJ11	1.65e-03	16	71	2	2.60.40.1400
Domain	K_chnl_inward-rec_Kir	KCNJ9 KCNJ11	1.65e-03	16	71	2	IPR016449
Domain	-	STARD9 ACOT12	3.42e-03	23	71	2	3.30.530.20
Domain	START-like_dom	STARD9 ACOT12	3.42e-03	23	71	2	IPR023393
Domain	PID	RABGAP1L ANKS1B	5.05e-03	28	71	2	PF00640
Domain	PID	RABGAP1L ANKS1B	6.57e-03	32	71	2	PS01179
Pathway	REACTOME_GLYCOSAMINOGLYCAN_METABOLISM	STAB2 HS6ST2 HS3ST6 B3GAT1 CHPF2 CHST13	1.33e-05	123	60	6	MM14623
Pathway	REACTOME_GLYCOSAMINOGLYCAN_METABOLISM	STAB2 HS6ST2 HS3ST6 B3GAT1 CHPF2 CHST13	1.53e-05	126	60	6	M695
Pathway	WP_GLYCOSAMINOGLYCAN_SYNTHESIS_IN_FIBROBLASTS	HS6ST2 B3GAT1 CHPF2 CHST13	2.67e-05	41	60	4	M48095
Pathway	KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE	B3GAT1 CHPF2 CHST13	1.07e-04	22	60	3	M19166
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	STAB2 HS6ST2 HS3ST6 B3GAT1 CHPF2 NUP93 CHST13	1.45e-04	271	60	7	MM15406
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	STAB2 HS6ST2 HS3ST6 B3GAT1 CHPF2 NUP93 CHST13	2.11e-04	288	60	7	M16864
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DENND4A TSR1 ABCE1 STARD9 AHCY MCM5 CDC73 NUP93 BSN TIMM44 SEC61A1 NDUFS1 TOP2A SLC5A2 CHST13	1.84e-07	1425	72	15	30948266
Pubmed	Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.	SEC61A2 SEC61A1	4.23e-06	2	72	2	18480044
Pubmed	BTG/Tob family members Tob1 and Tob2 inhibit proliferation of mouse embryonic stem cells via Id3 mRNA degradation.	TOB2 TOB1	1.27e-05	3	72	2	25951976
Pubmed	Evidence providing new insights into TOB-promoted deadenylation and supporting a link between TOB's deadenylation-enhancing and antiproliferative activities.	TOB2 TOB1	1.27e-05	3	72	2	22252318
Pubmed	Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover.	TWIST2 CDC73	1.27e-05	3	72	2	28384511
Pubmed	A serine/threonine kinase p90rsk1 phosphorylates the anti-proliferative protein Tob.	TOB2 TOB1	1.27e-05	3	72	2	11260258
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	POLR1F ABCE1 CWC27 CDK12 AHCY MCM5 NUP93 TOP2A PRRC2B	1.43e-05	701	72	9	30196744
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PTPN2 ABCE1 CDK12 AHCY MCM5 CDC73 TIMM44 SEC61A1 TOP2A	1.48e-05	704	72	9	29955894
Pubmed	KAP1 promotes proliferation and metastatic progression of breast cancer cells.	ZNF274 ZKSCAN8	2.53e-05	4	72	2	25421577
Pubmed	Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system.	TOB2 TOB1	2.53e-05	4	72	2	12135500
Pubmed	The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment.	SEC61A2 SEC61A1	2.53e-05	4	72	2	10212142
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SEC61A2 DENND4A CWC27 STARD9 ANKS1B MCM5 BSN POLQ SEC61A1 NDUFS1 TOP2A PRRC2B	3.78e-05	1442	72	12	35575683
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	POLR1F SEC61A2 PTPN2 ABCE1 SHPRH MCM5 NUP93 SEC61A1 NDUFS1 PRRC2B	4.11e-05	1005	72	10	19615732
Pubmed	Calnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complex.	SEC61A2 SEC61A1	4.21e-05	5	72	2	9565615
Pubmed	Apoptosis during embryonic tissue remodeling is accompanied by cell senescence.	TOB2 TOB1	4.21e-05	5	72	2	26568417
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	POLR1F PTPN2 TSR1 ABCE1 CDK12 KLF5 MCM5 CDC73 NUP93 TOP2A	4.43e-05	1014	72	10	32416067
Pubmed	TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells.	TOB2 TOB1	6.31e-05	6	72	2	38165569
Pubmed	Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.	SEC61A2 SEC61A1	6.31e-05	6	72	2	16705175
Pubmed	In search of a function for the TIS21/PC3/BTG1/TOB family.	TOB2 TOB1	6.31e-05	6	72	2	11377414
Pubmed	Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases.	TOB2 TOB1	8.82e-05	7	72	2	10602502
Pubmed	Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complex.	TOB2 TOB1	8.82e-05	7	72	2	11429045
Pubmed	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	PTPN2 BSN	8.82e-05	7	72	2	17554261
Pubmed	Identification of SCAN dimerization domains in four gene families.	ZNF274 ZKSCAN8	8.82e-05	7	72	2	11342224
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CDC42BPA SEMA7A KCNG1 CDK12 KCNJ11 USP40 NFX1 MCM5 PLEKHM1 PRRC2B	9.04e-05	1105	72	10	35748872
Pubmed	Aire's partners in the molecular control of immunological tolerance.	MCM5 NUP93 TOP2A	1.13e-04	45	72	3	20085707
Pubmed	Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes.	PTPN2 KCNJ11	1.17e-04	8	72	2	19264985
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	KPNA5 TSR1 CWC27 CDK12 RABGAP1L AHCY MCM5 CDC73 EFHB POLQ	1.28e-04	1153	72	10	29845934
Pubmed	Mammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencing.	TOB2 TOB1	1.51e-04	9	72	2	21726813
Pubmed	Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.	TOB2 TOB1	1.51e-04	9	72	2	17785442
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	KPNA5 PTPN2 LSR ABCE1 MCM5 CDC73 NUP93 SEC61A1 PRRC2B	1.79e-04	974	72	9	28675297
Pubmed	Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity.	TOB2 TOB1	1.88e-04	10	72	2	16890162
Pubmed	Differential gene expression of the intermediate and outer interzone layers of developing articular cartilage in murine embryos.	GDF5 LILRB2	2.30e-04	11	72	2	24738827
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	SEC61A2 CDC42BPA TSR1 ABCE1 AHCY MCM5 NUP93 SEC61A1 NDUFS1 TOP2A	2.41e-04	1247	72	10	27684187
Pubmed	The role of assembly in insulin's biosynthesis.	SEC61A2 SEC61A1	2.75e-04	12	72	2	9631292
Pubmed	Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.	TOB2 AHCY MCM5 SLC30A9 BEX2 TOP2A	2.78e-04	432	72	6	7671812
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	TSR1 ABCE1 AHCY MCM5 CHPF2 NUP93 NDUFS1	2.79e-04	613	72	7	22268729
Pubmed	Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.	GABRB2 BSN GRM2	2.95e-04	62	72	3	19367581
Pubmed	Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.	SEMA7A BSN	3.25e-04	13	72	2	20624980
Pubmed	A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.	CDK12 CDC73 TOP2A	3.39e-04	65	72	3	27453043
Pubmed	Transcription profile during maternal to zygotic transition in the mouse embryo.	LSR ABCE1	3.78e-04	14	72	2	16930510
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	CWC27 HS6ST2 CHPF2 SLC30A9 PRRC2B	3.91e-04	298	72	5	32353859
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DENND4A TSR1 ABCE1 CDK12 CHPF2 SEC61A1 PRRC2B	3.97e-04	650	72	7	38777146
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	TSR1 ABCE1 CDK12 MCM5 CDC73 BSN TIMM44	4.08e-04	653	72	7	33742100
Pubmed	The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans.	POLR1F TOP2A	4.36e-04	15	72	2	36271492
Pubmed	International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels.	KCNJ9 KCNJ11	4.36e-04	15	72	2	16382105
Pubmed	LINKIN, a new transmembrane protein necessary for cell adhesion.	LSR TSR1 ABCE1 AHCY SEC61A1 NDUFS1	4.85e-04	480	72	6	25437307
Pubmed	A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.	STARD9 SCG5	4.98e-04	16	72	2	7633422
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GABRB2 PTPN2 CDC42BPA ABCE1 RABGAP1L ANKS1B BSN TIMM44 NDUFS1	5.61e-04	1139	72	9	36417873
Pubmed	Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation.	GDF5 TWIST2	5.63e-04	17	72	2	15371327
Pubmed	On the integration of alcohol-related quantitative trait loci and gene expression analyses.	SCG5 KCNJ9	6.33e-04	18	72	2	15597075
Pubmed	Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.	TSR1 MCM5 GRM2 SEC61A1 TOP2A	6.46e-04	333	72	5	36779763
Pubmed	Tagging genes with cassette-exchange sites.	LSR TSR1 CDK12 RABGAP1L CDC73	6.64e-04	335	72	5	15741177
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	LSR ZNF274 KLF5 NFX1 ZKSCAN8 TWIST2 NR1I3	6.64e-04	709	72	7	22988430
Pubmed	A single cell transcriptional atlas of early synovial joint development.	GDF5 TWIST2	7.84e-04	20	72	2	32580935
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	ABCE1 AHCY MCM5 CDC73 NUP93 NDUFS1	8.45e-04	534	72	6	35032548
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	MCM5 CDC73 NUP93 PRRC2B	8.50e-04	203	72	4	22083510
Pubmed	Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.	SCG5 AHCY	8.65e-04	21	72	2	9616220
Pubmed	Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development.	HS6ST2 HS3ST6 B3GAT1	8.78e-04	90	72	3	30228991
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	ZKSCAN8 CDC73 NUP93 TIMM44 NDUFS1	9.16e-04	360	72	5	33111431
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	DENND4A CWC27 CDK12 TOGARAM1 PRRC2B	9.28e-04	361	72	5	26167880
Pubmed	Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.	TSR1 ABCE1	9.50e-04	22	72	2	32680882
Pubmed	Rare independent mutations in renal salt handling genes contribute to blood pressure variation.	KCNJ9 KCNJ11	9.50e-04	22	72	2	18391953
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SEC61A2 PTPN2 ABCE1 NFX1 SLC30A9 TIMM44 SEC61A1 NDUFS1 TOP2A PRRC2B	9.95e-04	1496	72	10	32877691
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	SHPRH CDC73 SEC61A1 TOP2A	9.98e-04	212	72	4	33853758
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	POLR1F LSR CDC42BPA TSR1 CWC27 CDK12 NFX1 MCM5 NDUFS1 NR1I3	1.00e-03	1497	72	10	31527615
Pubmed	Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells.	MCM5 CDC73 TOP2A	1.03e-03	95	72	3	29490077
Pubmed	Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum.	SEMA7A MCM5	1.04e-03	23	72	2	22817342
Pubmed	Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.	HEPACAM SLC30A9 GRM2 NDUFS1	1.05e-03	215	72	4	36808153
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	KPNA5 SEC61A2 ABCE1 AHCY MCM5 NUP93 TIMM44 SEC61A1 NDUFS1	1.13e-03	1257	72	9	37317656
Pubmed	Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function.	HS6ST2 HS3ST6	1.13e-03	24	72	2	34653670
Pubmed	Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.	HS6ST2 KLF5	1.43e-03	27	72	2	24496616
Pubmed	Genetic risk profiling and prediction of disease course in Crohn's disease patients.	PTPN2 BSN	1.54e-03	28	72	2	19422935
Pubmed	Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.	GABRB2 BEX2	1.54e-03	28	72	2	24427155
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	POLR1F TSR1 ABCE1 MCM5 NUP93 TIMM44 SEC61A1 NDUFS1 TOP2A	1.56e-03	1318	72	9	30463901
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TOB2 STARD9 RABGAP1L CHPF2 PRRC2B	1.58e-03	407	72	5	12693553
Pubmed	Phospho-tyrosine dependent protein-protein interaction network.	RABGAP1L ANKS1B TWIST2 NT5C PRRC2B	1.63e-03	410	72	5	25814554
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	NOL4 TSR1 CWC27 SHPRH ZKSCAN8 TOP2A	1.64e-03	608	72	6	36089195
Pubmed	Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation.	KLF5 SI	1.65e-03	29	72	2	16230531
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	MCM5 NUP93 POLQ TOP2A	1.83e-03	250	72	4	33536335
Pubmed	Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity.	HS6ST2 KLF5	1.89e-03	31	72	2	28942923
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TSR1 NFX1 MCM5 NUP93 TIMM44 TOP2A PRRC2B	1.93e-03	853	72	7	28718761
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	LSR DENND4A SHPRH MCM5	1.96e-03	255	72	4	15324660
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ABCE1 KLF5 AHCY MCM5 CDC73 NUP93 TOP2A PRRC2B	1.98e-03	1103	72	8	34189442
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	POLR1F LSR DENND4A CDC42BPA STARD9 RABGAP1L NUP93	2.03e-03	861	72	7	36931259
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CDC42BPA TSR1 CDK12 STARD9 AHCY NFX1 NUP93 TIMM44 PRRC2B	2.04e-03	1371	72	9	36244648
GeneFamily	BTG/Tob family	TOB2 TOB1	1.40e-04	6	56	2	1309
GeneFamily	Sulfotransferases, membrane bound	HS6ST2 HS3ST6 CHST13	2.03e-04	37	56	3	763
GeneFamily	StAR related lipid transfer domain containing	STARD9 ACOT12	9.64e-04	15	56	2	759
GeneFamily	Potassium voltage-gated channel subfamily J	KCNJ9 KCNJ11	1.10e-03	16	56	2	276
GeneFamily	Beta 3-glycosyltransferases	B3GNT9 CHPF2	2.49e-03	24	56	2	426
GeneFamily	Immunoglobulin like domain containing	HEPACAM LSR SEMA7A SIGIRR	3.00e-03	193	56	4	594
ToppCell	droplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A HS6ST2 KLF5 HS3ST6 KIAA1755 PLEKHM1	4.51e-07	176	73	6	533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM5 POLQ TOP2A NR1I3 SLC5A2	1.14e-05	179	73	5	804aa3899585fc7e662eff9f6d41f48655f16dd6
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NOL4 SCG5 KLF5 HS3ST6 BEX2	1.30e-05	184	73	5	e0e5a553fb8c0947679634396d20c2ca8455b932
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NOL4 SCG5 KLF5 HS3ST6 BEX2	1.30e-05	184	73	5	c3b848e1438a84b3fac8a4e40f3db478cc84d970
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-lung_neuroendocrine_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOL4 SCG5 KLF5 HS3ST6 BEX2	1.33e-05	185	73	5	30263c558ee331e0879abcf8b4c2427ff05f9fe7
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-Neuroendocrine\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOL4 SCG5 KLF5 HS3ST6 BEX2	1.33e-05	185	73	5	1b000ca11970db8f347eb97ff44605d562aea70a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 COL19A1 ANKS1B KIAA1755 NR1I3	1.37e-05	186	73	5	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	Neuronal_cells-Schwann_cells\|World / Lineage and Cell class	HEPACAM TMEM229A SCG5 ANKS1B B3GAT1	1.48e-05	189	73	5	371cdc92549269e45c23c5a5b3cae9c5d35ee217
ToppCell	Neuronal_cells\|World / Lineage and Cell class	HEPACAM TMEM229A SCG5 ANKS1B B3GAT1	1.48e-05	189	73	5	3948775a0ebd4b32c1623d5487f5581e6e2934d7
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Late_airway_progenitor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	LSR TOB1 KLF5 DLX3 BEX2	1.89e-05	199	73	5	494461665f945ce6c97299c58f7785e90dec5812
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI TOP2A CHST13	1.89e-05	199	73	5	06cf08b4a60670f583895a79488524b7b386b2f0
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-C_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	AHCY TWIST2 FAM174C SEC61A1 NT5C	1.94e-05	200	73	5	b6b59f56497b5a58e2d4eb6a97ada75c93729716
ToppCell	droplet-Fat-Scat-21m-Hematologic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 COL19A1 DLX3 CHST13	1.97e-05	97	73	4	440d45ecfc9b66cb61d734118601e745892d51e3
ToppCell	droplet-Fat-Scat-21m-Hematologic-erythroblast\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 COL19A1 DLX3 CHST13	1.97e-05	97	73	4	6fff45d4c4bbd81a67e1ad12b131cfe6a5ab37e6
ToppCell	severe-unassigned\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TWIST2 GRM2 POLQ TOP2A	5.84e-05	128	73	4	bef9cf0078fa8498d63f0723f1fa4a3c92405e10
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	B3GNT9 COL19A1 KLF5 TWIST2	1.20e-04	154	73	4	a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	DENND4A COL19A1 SEMA7A KCNG1	1.20e-04	154	73	4	e16f200391537aa1002b0079481b94e1fb86b9ad
ToppCell	Influenza_Severe-CD4+_Tcm\|World / Disease group and Cell class	LSR B3GNT9 TOB1 BEX2	1.29e-04	157	73	4	842ac087d3d51dba3a6b6937733b73a81aa15e1b
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM229A KCNG1 HS6ST2 ACOT12	1.45e-04	162	73	4	6972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NOL4 KCNG1 KIAA1755 SLC5A2	1.63e-04	167	73	4	55c3c68af269fcf40f2b080ae4489523609ad388
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NOL4 SCG5 KCNJ11 BEX2	1.75e-04	170	73	4	941d637cf76918ee4b0a1833abd1a42593cb8b1a
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 MCM5 TOP2A NR1I3	1.75e-04	170	73	4	6b91d4cbe0697b65bfb2e099e7a9b39ea2fba3a9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 KCNJ11 BSN BEX2	1.79e-04	171	73	4	99176a932569fa1c7e1c01009684f5a65244b96e
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACER2 LSR ANKS1B TOP2A	1.79e-04	171	73	4	621f9da0bfa09c86fc89fd26919403e94cd56d2b
ToppCell	Influenza_Severe-CD4+_Tcm\|Influenza_Severe / Disease group and Cell class	LSR B3GNT9 TOB1 BEX2	1.83e-04	172	73	4	47865a04968ca28c6ff125159d9a23e37c8b8af1
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCG5 KCNJ11 BSN BEX2	1.95e-04	175	73	4	c031da47ca63d1133e13530cbf779df9435e22cb
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LILRB2 EFHB POLQ TOP2A	1.95e-04	175	73	4	0b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 ABCE1 MCM5 TOP2A	2.00e-04	176	73	4	a9e77681bcd36c382d53eb6f771349d55f98d744
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCG5 ANKS1B B3GAT1 BSN	2.04e-04	177	73	4	0417460bdb012bc43d7254377fa53d79cdab3f34
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 ANKS1B KIAA1755 NR1I3	2.04e-04	177	73	4	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	SEMA7A MCM5 POLQ TOP2A	2.04e-04	177	73	4	ba701d3c90722d8bff70d0fa651899305cdad257
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF274 KLF5 USP40 NT5C	2.08e-04	178	73	4	89f0537459a321ded956bf70ad56fefc0854f8b0
ToppCell	COPD-Epithelial-PNEC\|Epithelial / Disease state, Lineage and Cell class	NOL4 SCG5 B3GAT1 BEX2	2.13e-04	179	73	4	988d0853c391da1e5004f73f3678047418d3f6d3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL19A1 ANKS1B KIAA1755 NR1I3	2.13e-04	179	73	4	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	Control-Developping_Plasmablast\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SCG5 POLQ SEC61A1 TOP2A	2.13e-04	179	73	4	9383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCell	wk_15-18-Epithelial-PNS-Early_Schwann\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SCG5 HS6ST2 KIAA1755 BSN	2.32e-04	183	73	4	7e8366ec8117d36cec67f77dcb0e9a6032d87fcb
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 COL19A1 ANKS1B KIAA1755	2.32e-04	183	73	4	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 ANKS1B KIAA1755 NR1I3	2.32e-04	183	73	4	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 NOL4 STAB2 COL19A1	2.36e-04	184	73	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 NOL4 STAB2 COL19A1	2.36e-04	184	73	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 NOL4 STAB2 COL19A1	2.36e-04	184	73	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 GDF5 NOL4 SCG5	2.36e-04	184	73	4	92314fcdb74c0a1262c9334c774819a2a49ba454
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 ANKS1B KIAA1755 NR1I3	2.36e-04	184	73	4	9434731f651820b05335085582960f08fbf895de
ToppCell	P28-Epithelial-alveolar_epithelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HEPACAM LSR KLF5 RABGAP1L	2.41e-04	185	73	4	5bb513e569f3a197d55ae2ca683e202daebabeac
ToppCell	facs-Skin-Anagen-3m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF5 MCM5 NUP93 NR1I3	2.46e-04	186	73	4	9a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	SEMA7A NFX1 SHPRH POLQ	2.46e-04	186	73	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 COL19A1 ANKS1B KIAA1755	2.46e-04	186	73	4	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	10x5'-Lung-Lymphocytic_Invariant-Inducer-like-ILC3\|Lung / Manually curated celltypes from each tissue	LSR STARD9 KLF5 BEX2	2.51e-04	187	73	4	0e7aa481effdd8c2fbdf8b65852821dec2d92cde
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 KCNJ11 BSN BEX2	2.51e-04	187	73	4	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LSR HS6ST2 KLF5 HS3ST6	2.62e-04	189	73	4	783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCell	facs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LSR HS6ST2 KLF5 HS3ST6	2.62e-04	189	73	4	88b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LSR HS6ST2 KLF5 HS3ST6	2.67e-04	190	73	4	47e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LSR HS6ST2 KLF5 HS3ST6	2.67e-04	190	73	4	261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD9 SCG5 POLQ TOP2A	2.67e-04	190	73	4	31de1727822e9818652946dfb962daee77ffad68
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LSR HS6ST2 KLF5 KIAA1755	2.67e-04	190	73	4	050d6e0546954675b6adbfecb67854b1e09739d1
ToppCell	facs-Pancreas\|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOL4 SCG5 KCNJ11 BEX2	2.72e-04	191	73	4	d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell	15-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	NOL4 SCG5 KCNJ11 BEX2	2.72e-04	191	73	4	76311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCell	droplet-Fat-Scat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF5 KCNJ11 HS3ST6 TTC22	2.78e-04	192	73	4	4098b5170c9995718758a082d1b8bcb86d5a289e
ToppCell	droplet-Fat-Scat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF5 KCNJ11 HS3ST6 TTC22	2.78e-04	192	73	4	936028fe851e8dd2b906df0210acc574c017b499
ToppCell	droplet-Fat-Scat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF5 KCNJ11 HS3ST6 TTC22	2.78e-04	192	73	4	62e55ed0d46b2e7b07dc42399972a099576cbc5f
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACER2 LSR KLF5 BEX2	2.83e-04	193	73	4	33c495a2a7252b48ce10321642fd675d03cc80fc
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOL4 TMEM229A COL19A1 HS6ST2	2.83e-04	193	73	4	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NOL4 SCG5 HS3ST6 BEX2	2.89e-04	194	73	4	ccff0b5814f5de2d42720018e7f5dc5dcdafb568
ToppCell	E16.5-Epithelial\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACER2 LSR KLF5 BEX2	2.95e-04	195	73	4	e2d9856e4bd6259f0988cfefd7ce364f15681bf8
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACER2 LSR MCM5 BEX2	2.95e-04	195	73	4	5276e874615823bb00e20ff160692e0946d7d400
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	B3GNT9 SEMA7A SIGIRR SCG5	2.95e-04	195	73	4	a045fb8a377e54fb57fef1181d4c3fc15d627ef6
ToppCell	11.5-Airway-Epithelial-Secretory_progenitor\|Airway / Age, Tissue, Lineage and Cell class	LSR TOB1 KLF5 BEX2	2.95e-04	195	73	4	8cbc78a6cb812f907c69b00f85263976216840ac
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NOL4 KCNJ11 BEX2 CHST13	2.95e-04	195	73	4	5f33ece997f074598b4201ff74f592ee07c86a06
ToppCell	E16.5-Epithelial-Epithelial_Alveolar\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACER2 LSR KLF5 BEX2	3.01e-04	196	73	4	1756254a61ea92601ed5e223ef4471f010c12216
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACER2 LSR KLF5 BEX2	3.01e-04	196	73	4	b236be2fc0144c77a8840081bbb6ac6913e996f8
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal-Subcortical\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	NOL4 SCG5 ANKS1B BEX2	3.01e-04	196	73	4	bf8fe28193348342987d361c8e8b9e1d6d542678
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACER2 LSR KLF5 BEX2	3.01e-04	196	73	4	caa3c9555e1c656e88246ed31388a818f77610a1
ToppCell	facs-Brain_Non-Myeloid\|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEPACAM TOB1 CDC42BPA ANKS1B	3.06e-04	197	73	4	a1f7eec1aca03432caa8fe817ff6d24b29d4062d
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area\|World / Primary Cells by Cluster	GABRB2 SCG5 B3GAT1 BEX2	3.06e-04	197	73	4	79b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI CHST13	3.06e-04	197	73	4	a6a27e5809ee2c9b56c7e06c35e4f140f9fa13ad
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TWIST2 GRM2 POLQ TOP2A	3.06e-04	197	73	4	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33\|World / Primary Cells by Cluster	GABRB2 SCG5 B3GAT1 BEX2	3.06e-04	197	73	4	d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDF5 B3GNT9 TOB1 CDC42BPA	3.06e-04	197	73	4	3fe665c0277d091290b63f0dd24c0c6536a45309
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB2 LSR KLF5 AHCY	3.12e-04	198	73	4	8e640e7b464c72ee41402f31dcc3b0032bdab277
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI CHST13	3.12e-04	198	73	4	8fbc461315986e357a0961a261ed10880637d6ad
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NOL4 KCNG1 B3GAT1 BEX2	3.12e-04	198	73	4	d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCell	Influenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_Tcm\|Influenza_Severe / Disease, condition lineage and cell class	LSR B3GNT9 TOB1 BEX2	3.12e-04	198	73	4	fc99f2e300d76126d05c0c43e11cdbbeb74f6f0d
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI CHST13	3.18e-04	199	73	4	722b9ebf7e47c361a7f192689a8d46947ec62b45
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI CHST13	3.18e-04	199	73	4	5f77d3892db7b0d657870ccd596e08a411928bfc
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI CHST13	3.18e-04	199	73	4	c9bd712cf401aec256a2cfaec5b580209e52c265
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB2 LSR KLF5 AHCY	3.18e-04	199	73	4	2f6cb5c9f08fc1b6b7771a0360c93a69a7319f13
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI CHST13	3.18e-04	199	73	4	9d24223b571fba202455c5bd49bd79530abf09c0
ToppCell	TCGA-Cervix-Primary_Tumor\|TCGA-Cervix / Sample_Type by Project: Shred V9	LSR KLF5 MCM5 TOP2A	3.18e-04	199	73	4	ef6fde26af2ca9e6cde198ac0e14e03d9ab398f8
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts\|lymph-node_spleen / Manually curated celltypes from each tissue	MCM5 POLQ SEC61A1 TOP2A	3.24e-04	200	73	4	b0d708715f09ec1f67fdef3b100a91c8ff2747a7
ToppCell	MS-IIF-Lymphocyte-T/NK-CD8+_Tcm\|IIF / Disease, condition lineage and cell class	LSR TOB1 KCNJ9 BEX2	3.24e-04	200	73	4	01554c0b7b8d7a12d99853fe057a20ed775ee5b2
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI CHST13	3.24e-04	200	73	4	eef5f6bd9ff5d985def8befcf45786234317f144
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LSR KLF5 SI CHST13	3.24e-04	200	73	4	4b1ae9f71f0fe998b06fa580885572d1fc1544e2
ToppCell	Influenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_T_naive\|Influenza_Severe / Disease, condition lineage and cell class	LSR B3GNT9 TOB1 BEX2	3.24e-04	200	73	4	0382f8fc27d18003761725e714beb6b3f3150057
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEPACAM TMEM229A CDC42BPA SEC61A1	3.24e-04	200	73	4	f0c338877e39226a90c4effe12f6501d33542a73
ToppCell	severe-immature_Neutrophil\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KLF5 TWIST2 POLQ TOP2A	3.24e-04	200	73	4	5ee43386da8261d2e7602a152e6ba4338d844e08
ToppCell	Calu_3\|World / Cell line, Condition and Strain	LSR SEMA7A KLF5 RABGAP1L	3.24e-04	200	73	4	a549aa08aeefe905653266dae3936094ff55f8e4
ToppCell	severe-immature_Neutrophil\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KLF5 TWIST2 POLQ TOP2A	3.24e-04	200	73	4	a9b87accdaa6956116ab82427e1330e8f007ef94
Disease	Back pain	POLR1F GDF5 KCNG1 BSN	6.22e-05	87	72	4	HP_0003418
Disease	pallidum volume change measurement	CWC27 EFHB	4.50e-04	13	72	2	EFO_0021494
Disease	susceptibility to vaginal yeast infection measurement	SCG5 ANKS1B CDC73	5.46e-04	65	72	3	EFO_0008412
Disease	hip circumference	GABRB2 GDF5 ANKS1B TOP2A PLEKHM1	1.43e-03	338	72	5	EFO_0005093
Disease	Hepatic Form of Wilson Disease	AHCY ANKS1B	1.57e-03	24	72	2	C1527352
Disease	Hepatolenticular Degeneration	AHCY ANKS1B	1.57e-03	24	72	2	C0019202
Disease	maximal oxygen uptake measurement	KIAA1755 NUP93	1.84e-03	26	72	2	EFO_0004887

Protein segments in the cluster

Peptide	Gene	Start	Entry
NYKLRGDARDPRIPR	B3GAT1	151	Q9P2W7
KQYRRRLREEFSFIP	CDK12	976	Q9NYV4
IYDPRNPVNKRRREE	CWC27	446	Q6UX04
VRRPDRKDLLGYLNG	CDC73	86	Q6P1J9
RRYLPKIFRNDRGRF	ACER2	111	Q5QJU3
RPVNGRRLYKDFVLN	GRM2	411	Q14416
PRIQPISKDDFRRYR	ACOT12	301	Q8WYK0
ERRKRRSVNPYLQGQ	SCG5	176	P05408
RRFQKAQYLALPERA	DLX3	146	O60479
QLFKRRNVYLPRNDE	KPNA5	46	O15131
RRALRNNTDPYKRAV	NUP93	376	Q8N1F7
LNIEIRDLRRPGRYF	DENND4A	1491	Q7Z401
RRGFLAREQYRALRP	NT5C	41	Q8TCD5
VAKFPENRNRNRYRD	PTPN2	36	P17706
PRRRGRQRYVEKDGR	KCNJ9	16	Q92806
RRRNENYFDDIPRSK	ANKS1B	1001	Q7Z6G8
LQSYIKGQQRRPRDR	NR1I3	296	Q14994
KGQQRRPRDRFLYAK	NR1I3	301	Q14994
EYLFSQRRKRRAPLA	GDF5	371	P43026
LQRRFKEFLRQYRVG	MCM5	31	P33992
RAFRLKKPQRRRYGL	FAM174C	91	Q9BVV8
RPYNLGFRRKVNLKA	KIAA1755	346	Q5JYT7
RGRPREAKFARYNLP	BSN	1791	Q9UPA5
RLAEDPAKPRYRARQ	KCNJ11	16	Q14654
YGARRNEQRRYPQKR	NFX1	231	Q12986
LYKEGERDLRQLPGR	LILRB2	256	Q8N423
DRLLKGYDIRLRPDF	GABRB2	41	P47870
KGAFYRRAQRLRPQD	KCNG1	36	Q9UIX4
LDGQPFLRYDRQKRR	MICB	51	Q29980
FLRYDRQKRRAKPQG	MICB	56	Q29980
RVQLPKRYRAEENAR	RABGAP1L	756	Q5R372
FRRDPNNYRPRINKL	ABCE1	566	P61221
YIFRNRELRPLFDRQ	COL19A1	156	Q14993
DRPIRGKEYVLNRNR	C19orf71	141	A6NCJ1
GNRRRFRVRQPILQY	BEX2	51	Q9BXY8
RRRYLPGIKDNNPYR	POLQ	2446	O75417
NRLPDEYLRGKDRQR	EFHB	531	Q8N7U6
PRYNFTRGDLLRKVD	HS6ST2	206	Q96MM7
LRPDYRDRIRLFENG	HEPACAM	91	Q14CZ8
IKPQVDRYRLKNGRR	AHCY	321	P23526
LVRRLQEFYRPFNRR	HS3ST6	316	Q96QI5
PLRYFGRDARARRAQ	LSR	31	Q86X29
LLDLFENGNYRRRRR	FOXL3	116	A0A1W2PRP0
PRCARRRKYQEQNIF	PLEKHM1	1041	Q9Y4G2
KVRALREAFYRQNLP	SEC61A2	226	Q9H9S3
QVFLKRFLRLRYGRQ	TMEM229A	171	B2RXF0
RFAYDGLKRQRLTEP	NDUFS1	291	P28331
RQGYLDALRFLERRG	PNPLA5	241	Q7Z6Z6
KPQLERRRGYKLFLD	SIGIRR	186	Q6IA17
DGRRLRNQKRYMAIP	SHPRH	791	Q149N8
NRFRFKITDPNNRRY	SI	156	P14410
LPSRRREYLQQLRKD	STARD9	4301	Q9P2P6
RNINNKRRYSFRVPE	CDC42BPA	1536	Q5VT25
RQFPEYQERARKRIR	NOL4	446	O94818
PFDFARYLRAKDQRR	B3GNT9	81	Q6UX72
FQRRYGARIVQRLRP	CHST13	196	Q8NET6
KQRLLNGYRRFDPAR	CHPF2	426	Q9P2E5
PRDVAARIRFQKYRG	TSR1	491	Q2NL82
PQYLRKRFGGRRIRL	SLC5A2	126	P31639
KVRALREAFYRQNLP	SEC61A1	226	P61619
DPEAARQRFRQFRYK	ZNF274	156	Q96GC6
YEELPKRRRQRGSEN	PRRC2B	1141	Q5JSZ5
IRKQEYNGKIPRFRR	SEMA7A	191	O75326
YNLPFKRNLEGCRER	STAB2	1926	Q8WWQ8
PRYLNRKRTGIREQL	POLR1F	61	Q3B726
LYNKLPRRRVNIFGE	TOB1	16	P50616
DRRQRKLLGLPEDYL	TOP2A	671	P11388
YRRPQRLRKRTEFAG	TIMM44	201	O43615
ILREYRDFLGNTKPR	SLC30A9	211	Q6PML9
RLGFPRRKEALYRAL	TOGARAM1	126	Q9Y4F4
RTDRQPLREYKLGRR	USP40	1036	Q9NVE5
LRRAQDKYPAARLRQ	TTC22	501	Q5TAA0
LYNKLPRRRADLFGE	TOB2	16	Q14106
RLRFRQLRYQETLGP	ZKSCAN8	51	Q15776
ELERQPKRFGRKRRY	TWIST2	21	Q8WVJ9
PVRYNRRSNPDLEKR	KLF5	356	Q13887