Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FBN1 FBN2 EDIL3 MUC2 MUC5AC TNXB

4.75e-07188326GO:0005201
GeneOntologyMolecularFunctionNotch binding

SNED1 MEGF10 NOTCH1

1.07e-0527323GO:0005112
GeneOntologyMolecularFunctioncalcium ion binding

SNED1 THBD FBN1 FBN2 EGF EDIL3 NOTCH1

1.51e-04749327GO:0005509
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN1 FBN2

1.63e-0412322GO:0030023
GeneOntologyMolecularFunctionintegrin binding

ESM1 FBN1 EDIL3 TNXB

1.69e-04175324GO:0005178
GeneOntologyMolecularFunctionreceptor ligand activity

FBN1 FBN2 EGF WNT2 WNT11 SEMA3E

2.03e-04547326GO:0048018
GeneOntologyMolecularFunctionsignaling receptor activator activity

FBN1 FBN2 EGF WNT2 WNT11 SEMA3E

2.18e-04554326GO:0030546
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN1 FBN2

2.24e-0414322GO:0097493
GeneOntologyMolecularFunctionsignaling receptor regulator activity

FBN1 FBN2 EGF WNT2 WNT11 SEMA3E

3.84e-04616326GO:0030545
GeneOntologyMolecularFunctionhistone modifying activity

EHMT1 SETD2 NAA40 PHF10

4.71e-04229324GO:0140993
GeneOntologyMolecularFunctionfrizzled binding

WNT2 WNT11

2.06e-0342322GO:0005109
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

EHMT1 SETD2

2.26e-0344322GO:0140938
GeneOntologyMolecularFunctionstructural molecule activity

FBN1 FBN2 EDIL3 MUC2 MUC5AC TNXB

2.60e-03891326GO:0005198
GeneOntologyMolecularFunctionmolecular function activator activity

FBN1 FBN2 EGF WNT2 NOTCH1 WNT11 SEMA3E

2.90e-031233327GO:0140677
GeneOntologyMolecularFunctionhistone acetyltransferase activity

NAA40 PHF10

3.02e-0351322GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

NAA40 PHF10

3.50e-0355322GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

NAA40 PHF10

4.16e-0360322GO:0034212
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

EHMT1 SETD2

5.31e-0368322GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

EHMT1 SETD2

5.46e-0369322GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

EHMT1 SETD2

5.77e-0371322GO:0042054
GeneOntologyMolecularFunctionextracellular matrix binding

ZAN TNXB

6.09e-0373322GO:0050840
GeneOntologyMolecularFunctionN-acetyltransferase activity

NAA40 PHF10

6.93e-0378322GO:0008080
GeneOntologyMolecularFunctionN-acyltransferase activity

NAA40 PHF10

1.16e-02102322GO:0016410
GeneOntologyMolecularFunctionprotein methyltransferase activity

EHMT1 SETD2

1.18e-02103322GO:0008276
GeneOntologyMolecularFunctionacetyltransferase activity

NAA40 PHF10

1.20e-02104322GO:0016407
GeneOntologyMolecularFunctionN-methyltransferase activity

EHMT1 SETD2

1.23e-02105322GO:0008170
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

1.40e-054322GO:0035583
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

SETD2 ASB2 EGF WNT2 NOTCH1 WNT11 SEMA3E

3.71e-05619327GO:0002009
GeneOntologyBiologicalProcesscardiac atrium development

WNT2 NOTCH1 WNT11

3.74e-0542323GO:0003230
GeneOntologyBiologicalProcessepithelial tube morphogenesis

SETD2 ASB2 EGF WNT2 NOTCH1 SEMA3E

4.03e-05421326GO:0060562
GeneOntologyBiologicalProcessembryo development

EHMT1 PRSS29P THBD SETD2 FBN2 ACVR2A ASB2 WNT2 NOTCH1 WNT11

4.08e-0514373210GO:0009790
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

SETD2 EGF WNT2 NOTCH1 SEMA3E

4.50e-05258325GO:0001763
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2

6.49e-058322GO:0071694
GeneOntologyBiologicalProcessregulation of ossification

SETD2 FBN2 ACVR2A NOTCH1

7.62e-05147324GO:0030278
GeneOntologyBiologicalProcessmesenchymal cell differentiation

TNXB WNT2 NOTCH1 WNT11 SEMA3E

8.62e-05296325GO:0048762
GeneOntologyBiologicalProcessembryonic morphogenesis

SETD2 FBN2 ACVR2A ASB2 WNT2 NOTCH1 WNT11

9.06e-05713327GO:0048598
GeneOntologyBiologicalProcesstissue morphogenesis

SETD2 ASB2 EGF WNT2 NOTCH1 WNT11 SEMA3E

1.24e-04750327GO:0048729
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

FBN1 FBN2

1.27e-0411322GO:0035581
GeneOntologyBiologicalProcesspositive regulation of ossification

SETD2 FBN2 ACVR2A

1.45e-0466323GO:0045778
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

FBN1 FBN2

1.80e-0413322GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

FBN1 FBN2

1.80e-0413322GO:1900116
GeneOntologyBiologicalProcesstube development

ESM1 SETD2 FBN1 ASB2 EGF WNT2 NOTCH1 WNT11 SEMA3E

2.03e-041402329GO:0035295
GeneOntologyBiologicalProcessanimal organ formation

WNT2 NOTCH1 WNT11

2.38e-0478323GO:0048645
GeneOntologyBiologicalProcessbranching morphogenesis of an epithelial tube

EGF WNT2 NOTCH1 SEMA3E

2.40e-04198324GO:0048754
GeneOntologyBiologicalProcesstube morphogenesis

ESM1 SETD2 ASB2 EGF WNT2 NOTCH1 WNT11 SEMA3E

2.48e-041125328GO:0035239
GeneOntologyBiologicalProcesscirculatory system development

ESM1 SETD2 FBN1 ASB2 EGF WNT2 NOTCH1 WNT11 SEMA3E

2.50e-041442329GO:0072359
GeneOntologyBiologicalProcessmesenchyme development

TNXB WNT2 NOTCH1 WNT11 SEMA3E

2.51e-04372325GO:0060485
GeneOntologyBiologicalProcessepithelial to mesenchymal transition

TNXB WNT2 NOTCH1 WNT11

2.64e-04203324GO:0001837
GeneOntologyBiologicalProcessbiomineral tissue development

FBN2 ACVR2A NOTCH1 WNT11

2.64e-04203324GO:0031214
GeneOntologyBiologicalProcessneuroendocrine cell differentiation

NOTCH1 WNT11

2.76e-0416322GO:0061101
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

ESM1 TMPRSS12 SETD2 FBN2 EGF WNT2 NOTCH1 WNT11 SEMA3E

3.09e-041483329GO:0048646
GeneOntologyBiologicalProcesscell-substrate adhesion

SNED1 EDIL3 TNXB NOTCH1 SEMA3E

3.92e-04410325GO:0031589
GeneOntologyBiologicalProcessskeletal muscle cell differentiation

ASB2 MEGF10 NOTCH1

4.39e-0496323GO:0035914
GeneOntologyBiologicalProcessblood vessel development

ESM1 SETD2 EGF WNT2 NOTCH1 WNT11 SEMA3E

4.60e-04929327GO:0001568
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

EGF WNT2 NOTCH1 SEMA3E

4.67e-04236324GO:0061138
GeneOntologyBiologicalProcessregulation of embryonic development

EHMT1 WNT2 NOTCH1

4.81e-0499323GO:0045995
GeneOntologyBiologicalProcessvasculature development

ESM1 SETD2 EGF WNT2 NOTCH1 WNT11 SEMA3E

5.92e-04969327GO:0001944
GeneOntologyBiologicalProcessstriated muscle cell proliferation

WNT2 MEGF10 NOTCH1

6.54e-04110323GO:0014855
GeneOntologyBiologicalProcessregulation of biomineral tissue development

FBN2 ACVR2A NOTCH1

7.26e-04114323GO:0070167
GeneOntologyBiologicalProcessregionalization

ACVR2A ASB2 WNT2 NOTCH1 WNT11

7.86e-04478325GO:0003002
GeneOntologyBiologicalProcesspericardium development

SETD2 NOTCH1

8.60e-0428322GO:0060039
GeneOntologyBiologicalProcessheart development

SETD2 FBN1 ASB2 WNT2 NOTCH1 WNT11

9.59e-04757326GO:0007507
GeneOntologyBiologicalProcesspeptidyl-lysine methylation

EHMT1 SETD2

9.87e-0430322GO:0018022
GeneOntologyBiologicalProcessmulti-organism reproductive process

PRSS29P THBD FBN2 ACVR2A

1.01e-03290324GO:0044703
GeneOntologyBiologicalProcessmulti-multicellular organism process

PRSS29P THBD FBN2 ACVR2A

1.06e-03294324GO:0044706
GeneOntologyBiologicalProcessosteoblast differentiation

FBN2 ACVR2A NOTCH1 WNT11

1.17e-03302324GO:0001649
GeneOntologyBiologicalProcesspattern specification process

ACVR2A ASB2 WNT2 NOTCH1 WNT11

1.21e-03526325GO:0007389
GeneOntologyBiologicalProcessmyoblast differentiation

PHF10 MEGF10 NOTCH1

1.21e-03136323GO:0045445
GeneOntologyBiologicalProcesscoronary vasculature morphogenesis

SETD2 NOTCH1

1.27e-0334322GO:0060977
GeneOntologyBiologicalProcesscardiac atrium morphogenesis

WNT2 NOTCH1

1.34e-0335322GO:0003209
GeneOntologyBiologicalProcessblood vessel morphogenesis

ESM1 SETD2 EGF NOTCH1 WNT11 SEMA3E

1.42e-03817326GO:0048514
GeneOntologyBiologicalProcessheart formation

NOTCH1 WNT11

1.42e-0336322GO:0060914
GeneOntologyBiologicalProcessepithelium development

SETD2 ASB2 EGF MUC2 WNT2 NOTCH1 WNT11 SEMA3E

1.46e-031469328GO:0060429
GeneOntologyBiologicalProcessheart morphogenesis

ASB2 WNT2 NOTCH1 WNT11

1.47e-03321324GO:0003007
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

TMPRSS12 FBN2 ACVR2A PHF10 TNXB WNT2 NOTCH1

1.55e-031141327GO:0045597
GeneOntologyBiologicalProcessbone mineralization

FBN2 ACVR2A WNT11

1.57e-03149323GO:0030282
GeneOntologyBiologicalProcesspositive regulation of cardiac muscle cell proliferation

WNT2 NOTCH1

1.58e-0338322GO:0060045
GeneOntologyBiologicalProcessembryonic organ development

SETD2 ASB2 WNT2 NOTCH1 WNT11

1.60e-03561325GO:0048568
GeneOntologyBiologicalProcessossification

SETD2 FBN2 ACVR2A NOTCH1 WNT11

1.62e-03562325GO:0001503
GeneOntologyBiologicalProcessdetermination of left/right symmetry

ACVR2A ASB2 NOTCH1

1.73e-03154323GO:0007368
GeneOntologyBiologicalProcesscardiac epithelial to mesenchymal transition

WNT2 NOTCH1

1.75e-0340322GO:0060317
GeneOntologyBiologicalProcesscell fate commitment

TNXB WNT2 NOTCH1 WNT11

1.77e-03338324GO:0045165
GeneOntologyBiologicalProcessameboidal-type cell migration

FBN2 EGF NOTCH1 WNT11 SEMA3E

1.81e-03577325GO:0001667
GeneOntologyBiologicalProcessmesoderm development

SETD2 ACVR2A WNT11

1.82e-03157323GO:0007498
GeneOntologyBiologicalProcessspecification of animal organ identity

WNT2 WNT11

1.84e-0341322GO:0010092
GeneOntologyBiologicalProcesscanonical Wnt signaling pathway

EGF WNT2 NOTCH1 WNT11

1.89e-03344324GO:0060070
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

ESM1 FBN1 FBN2 ACVR2A EGF TNXB NOTCH1

1.93e-031186327GO:0007167
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

FBN1 FBN2 ACVR2A NOTCH1

1.95e-03347324GO:0090092
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

WNT2 NOTCH1 WNT11

1.96e-03161323GO:0003206
GeneOntologyBiologicalProcessleft/right pattern formation

ACVR2A ASB2 NOTCH1

2.00e-03162323GO:0060972
GeneOntologyBiologicalProcessembryonic organ morphogenesis

SETD2 ASB2 NOTCH1 WNT11

2.03e-03351324GO:0048562
GeneOntologyBiologicalProcesscolumnar/cuboidal epithelial cell differentiation

MUC2 NOTCH1 WNT11

2.07e-03164323GO:0002065
GeneOntologyBiologicalProcessdetermination of bilateral symmetry

ACVR2A ASB2 NOTCH1

2.10e-03165323GO:0009855
GeneOntologyBiologicalProcessspecification of symmetry

ACVR2A ASB2 NOTCH1

2.10e-03165323GO:0009799
GeneOntologyBiologicalProcessregulation of cell migration

FBN2 EGF MUC2 TNXB NOTCH1 WNT11 SEMA3E

2.18e-031211327GO:0030334
GeneOntologyBiologicalProcessregulation of mesenchymal cell proliferation

WNT2 WNT11

2.21e-0345322GO:0010464
GeneOntologyBiologicalProcessskeletal system development

SETD2 FBN1 FBN2 ACVR2A WNT11

2.40e-03615325GO:0001501
GeneOntologyBiologicalProcessapoptotic process involved in development

MEGF10 NOTCH1

2.41e-0347322GO:1902742
GeneOntologyCellularComponentextracellular matrix

SNED1 FBN1 SERPINB9 FBN2 ZAN EDIL3 MUC2 MUC5AC TNXB WNT2 WNT11

1.89e-096563211GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

SNED1 FBN1 SERPINB9 FBN2 ZAN EDIL3 MUC2 MUC5AC TNXB WNT2 WNT11

1.95e-096583211GO:0030312
GeneOntologyCellularComponentmucus layer

MUC2 MUC5AC

6.80e-063322GO:0070701
GeneOntologyCellularComponentcollagen-containing extracellular matrix

FBN1 SERPINB9 FBN2 EDIL3 MUC2 TNXB WNT2

1.26e-05530327GO:0062023
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2

1.75e-0413322GO:0001527
HumanPhenoAbnormal aortic valve morphology

EHMT1 FBN1 FBN2 TNXB NOTCH1 SEMA3E

5.48e-06289106HP:0001646
HumanPhenoAbnormal upper to lower segment ratio

FBN1 FBN2

1.04e-053102HP:0012772
HumanPhenoCrumpled ear

FBN1 FBN2

5.18e-056102HP:0009901
HumanPhenoAbnormal aortic valve cusp morphology

FBN1 FBN2 TNXB NOTCH1

5.70e-05121104HP:0031567
HumanPhenoThoracic aortic aneurysm

FBN1 FBN2 NOTCH1 SEMA3E

5.70e-05121104HP:0012727
HumanPhenoAbdominal aortic aneurysm

FBN1 FBN2 NOTCH1 SEMA3E

6.47e-05125104HP:0005112
HumanPhenoAbnormal mitral valve morphology

FBN1 FBN2 TNXB NOTCH1

1.19e-04146104HP:0031477
HumanPhenoAortic dilatation

FBN1 FBN2 NOTCH1 SEMA3E

2.05e-04168104HP:0001724
HumanPhenoAortic aneurysm

FBN1 FBN2 NOTCH1 SEMA3E

2.05e-04168104HP:0004942
HumanPhenoAbnormal tracheal morphology

EHMT1 SETD2 FBN2 SEMA3E

2.15e-04170104HP:0002778
HumanPhenoCardiac valve calcification

FBN1 NOTCH1

2.67e-0413102HP:0005146
HumanPhenoAbnormal atrioventricular valve morphology

EHMT1 FBN1 FBN2 TNXB NOTCH1

2.81e-04350105HP:0006705
HumanPhenoTalipes

EHMT1 FBN1 FBN2 MEGF10 NOTCH1 SEMA3E

3.07e-04583106HP:0001883
HumanPhenoPositional foot deformity

EHMT1 FBN1 FBN2 MEGF10 NOTCH1 SEMA3E

3.19e-04587106HP:0005656
HumanPhenoAbnormal heart valve morphology

EHMT1 FBN1 FBN2 TNXB NOTCH1 SEMA3E

3.22e-04588106HP:0001654
HumanPhenoAbnormal aortic morphology

EHMT1 FBN1 FBN2 NOTCH1 SEMA3E

3.34e-04363105HP:0030963
HumanPhenoVascular dilatation

FBN1 FBN2 NOTCH1 SEMA3E

5.30e-04215104HP:0002617
HumanPhenoAbnormal aortic morphology

EHMT1 FBN1 FBN2 NOTCH1 SEMA3E

5.33e-04401105HP:0001679
HumanPhenoTall stature

EHMT1 SETD2 FBN1 FBN2

6.31e-04225104HP:0000098
DomainEGF_3

SNED1 THBD FBN1 FBN2 EGF ZAN EDIL3 TNXB MEGF10 NOTCH1

2.89e-122353110PS50026
DomainEGF

SNED1 THBD FBN1 FBN2 EGF ZAN EDIL3 TNXB MEGF10 NOTCH1

2.89e-122353110SM00181
DomainEGF-like_dom

SNED1 THBD FBN1 FBN2 EGF ZAN EDIL3 TNXB MEGF10 NOTCH1

5.14e-122493110IPR000742
DomainEGF_1

SNED1 THBD FBN1 FBN2 EGF ZAN EDIL3 TNXB MEGF10 NOTCH1

6.51e-122553110PS00022
DomainEGF-like_CS

SNED1 THBD FBN1 FBN2 EGF ZAN EDIL3 TNXB MEGF10 NOTCH1

8.19e-122613110IPR013032
DomainEGF_2

SNED1 THBD FBN1 FBN2 EGF ZAN EDIL3 TNXB MEGF10 NOTCH1

9.52e-122653110PS01186
DomainEGF_Ca-bd_CS

SNED1 THBD FBN1 FBN2 EGF EDIL3 NOTCH1

1.94e-1097317IPR018097
DomainEGF_CA

SNED1 THBD FBN1 FBN2 EGF EDIL3 NOTCH1

2.25e-1099317PS01187
DomainASX_HYDROXYL

SNED1 THBD FBN1 FBN2 EGF EDIL3 NOTCH1

2.41e-10100317PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SNED1 THBD FBN1 FBN2 EGF EDIL3 NOTCH1

3.65e-10106317IPR000152
DomainhEGF

SNED1 FBN2 EDIL3 MEGF10 NOTCH1

8.59e-1028315PF12661
DomainEGF_CA

SNED1 THBD FBN1 FBN2 EGF EDIL3 NOTCH1

9.85e-10122317SM00179
DomainEGF-like_Ca-bd_dom

SNED1 THBD FBN1 FBN2 EGF EDIL3 NOTCH1

1.10e-09124317IPR001881
DomainEGF

SNED1 THBD EGF ZAN EDIL3 TNXB NOTCH1

1.24e-09126317PF00008
DomainGrowth_fac_rcpt_

ESM1 THBD FBN1 FBN2 EGF TNXB NOTCH1

5.51e-09156317IPR009030
DomainEGF_CA

THBD FBN1 FBN2 EGF NOTCH1

2.85e-0786315PF07645
DomainTIL

ZAN MUC2 MUC5AC

9.02e-0712313PF01826
DomainC8

ZAN MUC2 MUC5AC

9.02e-0712313PF08742
DomainUnchr_dom_Cys-rich

ZAN MUC2 MUC5AC

1.17e-0613313IPR014853
DomainC8

ZAN MUC2 MUC5AC

1.17e-0613313SM00832
DomainTIL_dom

ZAN MUC2 MUC5AC

1.49e-0614313IPR002919
DomainVWFD

ZAN MUC2 MUC5AC

2.28e-0616313PS51233
DomainVWD

ZAN MUC2 MUC5AC

2.28e-0616313SM00216
DomainVWF_type-D

ZAN MUC2 MUC5AC

2.28e-0616313IPR001846
DomainVWD

ZAN MUC2 MUC5AC

2.28e-0616313PF00094
DomainEGF_extracell

EDIL3 TNXB MEGF10 NOTCH1

2.84e-0660314IPR013111
DomainEGF_2

EDIL3 TNXB MEGF10 NOTCH1

2.84e-0660314PF07974
DomainVWC_out

ZAN MUC2 MUC5AC

3.94e-0619313SM00215
DomainFBN

FBN1 FBN2

7.99e-063312IPR011398
DomaincEGF

THBD FBN1 FBN2

1.05e-0526313IPR026823
DomaincEGF

THBD FBN1 FBN2

1.05e-0526313PF12662
DomainVWFC_1

ZAN MUC2 MUC5AC

2.85e-0536313PS01208
DomainVWC

ZAN MUC2 MUC5AC

3.36e-0538313SM00214
DomainVWFC_2

ZAN MUC2 MUC5AC

3.36e-0538313PS50184
DomainWxxW_domain

MUC2 MUC5AC

3.98e-056312IPR025155
DomainMucin2_WxxW

MUC2 MUC5AC

3.98e-056312PF13330
DomainVWF_dom

ZAN MUC2 MUC5AC

4.55e-0542313IPR001007
DomainTB

FBN1 FBN2

5.57e-057312PF00683
Domain-

FBN1 FBN2

7.42e-0583123.90.290.10
DomainTB

FBN1 FBN2

9.53e-059312PS51364
DomainTB_dom

FBN1 FBN2

9.53e-059312IPR017878
DomainCTCK_1

MUC2 MUC5AC

4.01e-0418312PS01185
DomainWnt

WNT2 WNT11

4.48e-0419312IPR005817
DomainWNT1

WNT2 WNT11

4.48e-0419312SM00097
DomainWnt_CS

WNT2 WNT11

4.48e-0419312IPR018161
Domainwnt

WNT2 WNT11

4.48e-0419312PF00110
DomainWNT1

WNT2 WNT11

4.48e-0419312PS00246
DomainCT

MUC2 MUC5AC

6.03e-0422312SM00041
DomainCys_knot_C

MUC2 MUC5AC

7.81e-0425312IPR006207
DomainCTCK_2

MUC2 MUC5AC

7.81e-0425312PS01225
DomainSET

EHMT1 SETD2

2.10e-0341312PF00856
DomainSET

EHMT1 SETD2

2.64e-0346312SM00317
DomainSET_dom

EHMT1 SETD2

3.11e-0350312IPR001214
DomainSET

EHMT1 SETD2

3.11e-0350312PS50280
DomainAnk_2

EHMT1 ASB2 NOTCH1

5.33e-03215313PF12796
DomainAnk

EHMT1 ASB2 NOTCH1

6.27e-03228313PF00023
DomainPHD

PHF10 PHRF1

6.86e-0375312PF00628
DomainZnf_PHD-finger

PHF10 PHRF1

7.59e-0379312IPR019787
Domain-

EHMT1 ASB2 NOTCH1

7.90e-032483131.25.40.20
DomainANK

EHMT1 ASB2 NOTCH1

8.17e-03251313SM00248
DomainANK_REPEAT

EHMT1 ASB2 NOTCH1

8.35e-03253313PS50088
PathwayWP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY

EGF WNT2 NOTCH1

5.45e-0548223M39427
PathwayWP_BREAST_CANCER_PATHWAY

EGF WNT2 NOTCH1 WNT11

8.60e-05154224M39739
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

EGF NOTCH1

1.27e-0411222M48021
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

EGF WNT2 WNT11

3.00e-0485223M48315
PathwayPID_INTEGRIN5_PATHWAY

FBN1 EDIL3

3.12e-0417222M212
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

WNT2 NOTCH1

3.12e-0417222M39443
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY

EGF ARPC1A

4.80e-0421222M47722
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC2 MUC5AC

4.80e-0421222MM15706
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT2 WNT11

6.82e-0425222MM14940
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 FBN2

6.82e-0425222M39713
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT2 WNT11

7.39e-0426222M27239
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

EGF WNT2 WNT11

7.46e-04116223MM15863
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

EGF WNT2 WNT11

7.65e-04117223M39530
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

WNT2 NOTCH1 WNT11

7.84e-04118223M39852
PathwayWP_GASTRIC_CANCER_NETWORK_1

ESM1 NOTCH1

8.57e-0428222M39347
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2

1.12e-0332222MM14854
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

WNT2 WNT11

1.42e-0336222M39699
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2

1.50e-0337222M27134
PathwayREACTOME_SIGNALING_BY_NOTCH

EGF NOTCH1

1.66e-0339222MM14604
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2

1.66e-0339222MM14601
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

WNT2 NOTCH1 WNT11

1.92e-03161223M39770
PathwayPID_INTEGRIN3_PATHWAY

FBN1 EDIL3

2.02e-0343222M53
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

WNT2 WNT11

2.11e-0344222MM15878
PathwayKEGG_LYSINE_DEGRADATION

EHMT1 SETD2

2.11e-0344222M13720
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2

2.11e-0344222M26969
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

EHMT1 SETD2

2.31e-0346222MM14933
PathwayREACTOME_SIGNALING_BY_NOTCH3

EGF NOTCH1

2.62e-0349222M618
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

8.73e-07233212399449
Pubmed

Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.

MUC2 MUC5AC

8.73e-07233217203232
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

8.73e-07233221851253
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

8.73e-07233212429739
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

8.73e-07233230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

8.73e-07233221440062
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

8.73e-07233215131124
Pubmed

Thyroid hormone regulates protease expression and activation of Notch signaling in implantation and embryo development.

PRSS29P NOTCH1

8.73e-07233228993437
Pubmed

Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.

MUC2 MUC5AC

8.73e-07233212527922
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

8.73e-07233212524050
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

8.73e-07233220404337
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

8.73e-0723328791520
Pubmed

Epidermal Growth Factor Removal or Tyrphostin AG1478 Treatment Reduces Goblet Cells & Mucus Secretion of Epithelial Cells from Asthmatic Children Using the Air-Liquid Interface Model.

EGF MUC5AC

8.73e-07233226057128
Pubmed

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

FBN1 FBN2

8.73e-0723328120105
Pubmed

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.

FBN1 FBN2

8.73e-07233235419902
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

8.73e-0723328307578
Pubmed

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

FBN1 FBN2

8.73e-07233210504303
Pubmed

Severe neonatal presentation of Kleefstra syndrome in a patient with hypoplastic left heart syndrome and 9q34.3 microdeletion.

EHMT1 NOTCH1

8.73e-07233225380126
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

8.73e-0723327744963
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

8.73e-07233226408953
Pubmed

The landscape of genetic mutations in patients with chronic lymphocytic leukaemia and complex karyotype.

SETD2 NOTCH1

8.73e-07233231344256
Pubmed

Mucolytic activity of bacterial and human chitinases.

MUC2 MUC5AC

8.73e-07233217321686
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

8.73e-07233218006876
Pubmed

Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.

MUC2 MUC5AC

8.73e-07233220731025
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

8.73e-07233224833718
Pubmed

In vivo glycosylation of mucin tandem repeats.

MUC2 MUC5AC

8.73e-07233211445551
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

8.73e-07233224265020
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

8.73e-07233220529844
Pubmed

Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.

FBN1 FBN2

8.73e-07233225524144
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.

MUC2 MUC5AC

8.73e-07233223832517
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.

MUC2 MUC5AC

8.73e-07233223832516
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

8.73e-07233223133647
Pubmed

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

FBN1 FBN2

8.73e-07233216407178
Pubmed

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

FBN1 FBN2

8.73e-0723321852206
Pubmed

Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.

MUC2 MUC5AC

8.73e-07233214594655
Pubmed

N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.

FBN1 FBN2

8.73e-07233210359653
Pubmed

Epidermal growth factor regulates NIKS keratinocyte proliferation through Notch signaling.

EGF NOTCH1

8.73e-07233223899513
Pubmed

Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.

MUC2 MUC5AC

8.73e-07233212820724
Pubmed

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.

FBN1 WNT2 WNT11

1.02e-062133317943183
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

FBN1 FBN2 EDIL3 TNXB

1.35e-068633428327460
Pubmed

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.

EDIL3 WNT2 WNT11

2.51e-062833320940229
Pubmed

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.

EDIL3 WNT2 WNT11

2.51e-062833318367557
Pubmed

Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.

FBN1 FBN2

2.62e-06333210825173
Pubmed

Inhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1.

NOTCH1 WNT11

2.62e-06333222715413
Pubmed

MUC5AC expression through bidirectional communication of Notch and epidermal growth factor receptor pathways.

MUC5AC NOTCH1

2.62e-06333221622856
Pubmed

Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.

MEGF10 NOTCH1

2.62e-06333228498977
Pubmed

Differences in the expression of mucins in various forms of cystitis glandularis.

MUC2 MUC5AC

2.62e-06333217659847
Pubmed

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

FBN1 FBN2

2.62e-06333230201140
Pubmed

Notch signaling contributes to the expression of cardiac markers in human circulating progenitor cells.

NOTCH1 WNT11

2.62e-06333217967789
Pubmed

Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.

MUC2 MUC5AC

2.62e-06333218825309
Pubmed

Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.

MUC2 MUC5AC

2.62e-06333218300795
Pubmed

Gene expression profiling of colorectal mucinous adenocarcinomas.

MUC2 MUC5AC

2.62e-06333220485009
Pubmed

Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.

MUC2 MUC5AC

2.62e-06333217333267
Pubmed

Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.

MUC2 MUC5AC

2.62e-06333223464473
Pubmed

Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.

MUC2 MUC5AC

2.62e-06333224920497
Pubmed

Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.

FBN1 FBN2

2.62e-06333220855508
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC2 MUC5AC

2.62e-06333219718741
Pubmed

Heritable Thoracic Aortic Disease Overview

FBN1 FBN2 NOTCH1

3.10e-063033320301299
Pubmed

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.

EDIL3 WNT2 WNT11

3.10e-063033336305473
Pubmed

NOTCH maintains developmental cardiac gene network through WNT5A.

WNT2 NOTCH1 WNT11

3.79e-063233330347193
Pubmed

The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways.

MUC5AC WNT2 NOTCH1

4.16e-063333323213461
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 FBN2

5.23e-06433212429738
Pubmed

Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.

MUC2 MUC5AC

5.23e-06433233154304
Pubmed

Immunohistochemical profiling of Wnt, NF-kappaB, Stat3 and Notch signaling in human epidermal tumors.

WNT2 NOTCH1

5.23e-06433218703315
Pubmed

Human eye development is characterized by coordinated expression of fibrillin isoforms.

FBN1 FBN2

5.23e-06433225406291
Pubmed

Gastric mucin expression in first-degree relatives of gastric cancer patients.

MUC2 MUC5AC

5.23e-06433224901817
Pubmed

Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.

FBN1 FBN2

5.23e-06433220729550
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2

5.23e-06433225034023
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC2 MUC5AC

5.23e-06433225638393
Pubmed

Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).

MUC2 MUC5AC

5.23e-06433236367122
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC2 MUC5AC

5.23e-06433217471237
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC2 MUC5AC

5.23e-06433222269464
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC2 MUC5AC

5.23e-06433214984930
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

MUC2 MUC5AC

5.23e-06433222691042
Pubmed

Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.

FBN1 FBN2

5.23e-06433216835936
Pubmed

Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis.

ESM1 NOTCH1

5.23e-06433220616313
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC2 MUC5AC

5.23e-06433229869461
Pubmed

[Expression and clinical significance of Mucin and E-cadherin in colorectal tumors].

MUC2 MUC5AC

5.23e-06433217991319
Pubmed

Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?

MUC2 MUC5AC

5.23e-06433220929551
Pubmed

Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells.

MUC2 MUC5AC

5.23e-06433212391274
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC2 MUC5AC

5.23e-06433223807779
Pubmed

Secretoneurin induces airway mucus hypersecretion by enhancing the binding of EGF to NRP1.

EGF MUC5AC

5.23e-06433224556756
Pubmed

MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.

MUC2 MUC5AC

5.23e-06433227298226
Pubmed

PGE(2) induces MUC2 and MUC5AC expression in human intrahepatic biliary epithelial cells via EP4/p38MAPK activation.

MUC2 MUC5AC

5.23e-06433223619266
Pubmed

Mucin expression profile in Barrett's, dysplasia, adenocarcinoma sequence in the esophagus.

MUC2 MUC5AC

5.23e-06433217401217
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC2 MUC5AC

5.23e-06433212676567
Pubmed

Expression profile of mucins (MUC1, MUC2, MUC5AC, and MUC6) in ovarian mucinous tumours: changes in expression from benign to malignant tumours.

MUC2 MUC5AC

5.23e-06433225298197
Pubmed

Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.

FBN1 FBN2 WNT2

5.92e-063733334323105
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC2 MUC5AC NOTCH1

8.09e-064133322675208
Pubmed

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.

FBN1 FBN2

8.72e-06533226601954
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC2 MUC5AC

8.72e-06533211062147
Pubmed

Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14.

MUC2 MUC5AC

8.72e-06533212507512
Pubmed

Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin.

FBN1 FBN2

8.72e-06533212590922
Pubmed

Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12.

MUC2 MUC5AC

8.72e-06533212135769
Pubmed

pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins.

MUC2 MUC5AC

8.72e-06533210611155
Pubmed

Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?

MUC2 MUC5AC

8.72e-06533222261707
Pubmed

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

FBN1 FBN2

8.72e-06533217255108
Pubmed

POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.

FBN1 FBN2

8.72e-06533234411563
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC2 MUC5AC

8.72e-06533216188033
Pubmed

Nrf2 Transcriptional Activity Governs Intestine Development.

MUC2 NOTCH1

8.72e-06533235682851
InteractionNTN5 interactions

FBN1 FBN2 NOTCH1

7.20e-0624323int:NTN5
Cytoband11p15.5

MUC2 MUC5AC PHRF1

8.54e-0511833311p15.5
Cytoband9q34.3

EHMT1 NOTCH1

2.66e-031063329q34.3
CytobandEnsembl 112 genes in cytogenetic band chr5q23

FBN2 MEGF10

3.23e-03117332chr5q23
CytobandEnsembl 112 genes in cytogenetic band chr11p15

MUC2 MUC5AC PHRF1

7.65e-03564333chr11p15
CytobandEnsembl 112 genes in cytogenetic band chr7q22

ZAN ARPC1A

1.09e-02219332chr7q22
CytobandEnsembl 112 genes in cytogenetic band chr2q37

SNED1 LINC00471

1.15e-02226332chr2q37
GeneFamilyWnt family|Endogenous ligands

WNT2 WNT11

2.85e-0419242360
GeneFamilyCD molecules|Mucins

MUC2 MUC5AC

3.49e-0421242648
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

EHMT1 SETD2

9.23e-0434242487
GeneFamilyProteases, serine

PRSS29P TMPRSS12

3.14e-0363242738
GeneFamilyAnkyrin repeat domain containing

EHMT1 ASB2 NOTCH1

3.89e-03242243403
GeneFamilyPHD finger proteins

PHF10 PHRF1

6.30e-039024288
GeneFamilyFibronectin type III domain containing

SNED1 TNXB

1.89e-02160242555
CoexpressionNABA_MATRISOME

SNED1 ESM1 FBN1 SERPINB9 FBN2 EGF EDIL3 MUC2 MUC5AC TNXB WNT2 MEGF10 WNT11 SEMA3E

5.86e-1210083314MM17056
CoexpressionNABA_MATRISOME

SNED1 ESM1 FBN1 SERPINB9 FBN2 EGF EDIL3 MUC2 MUC5AC TNXB WNT2 MEGF10 WNT11 SEMA3E

7.42e-1210263314M5889
CoexpressionNABA_CORE_MATRISOME

SNED1 ESM1 FBN1 FBN2 EDIL3 TNXB

9.91e-07270336MM17057
CoexpressionNABA_CORE_MATRISOME

SNED1 ESM1 FBN1 FBN2 EDIL3 TNXB

1.10e-06275336M5884
CoexpressionNABA_MATRISOME_ASSOCIATED

SERPINB9 EGF MUC2 MUC5AC WNT2 MEGF10 WNT11 SEMA3E

2.83e-06738338MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

SERPINB9 EGF MUC2 MUC5AC WNT2 MEGF10 WNT11 SEMA3E

3.22e-06751338M5885
CoexpressionNABA_ECM_GLYCOPROTEINS

SNED1 FBN1 FBN2 EDIL3 TNXB

3.92e-06191335MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

SNED1 FBN1 FBN2 EDIL3 TNXB

4.45e-06196335M3008
CoexpressionGSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN

ESM1 ACVR2A ZAN NOTCH1

3.25e-05145334M359
CoexpressionGSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_UP

FBN1 TNXB WNT2 PEG3

1.05e-04196334M4972
CoexpressionYAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP

THBD TNXB PEG3

1.56e-0483333M10660
CoexpressionYAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP

THBD TNXB PEG3

2.05e-0491333MM622
CoexpressionWATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP

FBN1 EDIL3

2.59e-0419332M12084
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

SNED1 FBN1 FBN2 EDIL3 PEG3

4.78e-05288305gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000

SERPINB9 FBN2 ASB2 PHF10 MEGF10 ZNF551 SEMA3E

8.00e-05772307gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlasplacenta

FBN1 SERPINB9 FBN2 WNT2 PEG3

1.18e-04349305placenta
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500

SNED1 FBN2 EDIL3 PEG3

1.36e-04188304gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000

SERPINB9 FBN2 PHF10 MEGF10

1.57e-04195304gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBD FBN1 TNXB WNT2 SEMA3E

2.41e-07185335d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBD FBN1 TNXB WNT2 SEMA3E

2.89e-0719233530cefa0990ba1f379f350bfbf994a78db145075e
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBD FBN1 TNXB WNT2 SEMA3E

3.05e-071943357b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SNED1 FBN1 TNXB WNT2 SEMA3E

3.20e-07196335ee45e4de9d706ec87094e87f47d3e514539b8092
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SNED1 FBN1 TNXB WNT2 SEMA3E

3.20e-07196335fa4a85a3cd52df0da5dfedc0e584e9df8c61ce89
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TNXB WNT2 MEGF10 PEG3

3.37e-071983355e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SNED1 FBN2 ASB2 SEMA3E

6.57e-061653343d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

7.22e-061693348bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

7.22e-06169334bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

7.22e-061693345f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SNED1 FBN1 TNXB WNT11

7.74e-06172334e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBD FBN1 EDIL3 TNXB

9.26e-06180334f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

ESM1 FBN1 FBN2 WNT2

9.46e-06181334bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SNED1 TNXB WNT11 PEG3

9.88e-061833347eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBD SERPINB9 TNXB NOTCH1

9.88e-06183334bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.03e-051853343cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.03e-0518533400258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.03e-05185334a94694e226856bc5b168464f52d76004145717a5
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FBN1 FBN2 MEGF10 WNT11

1.03e-05185334427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 TNXB WNT2

1.03e-0518533401bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 TNXB MEGF10

1.03e-05185334785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 TNXB MEGF10

1.03e-0518533497a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 FBN2 TNXB PEG3

1.05e-05186334c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 TNXB WNT11 SEMA3E

1.08e-05187334fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.08e-051873347beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBD FBN1 TNXB WNT2

1.08e-051873340d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.08e-051873342c145e9d11424939dd99012a8cedf5d998b966e9
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 TNXB WNT2 WNT11

1.10e-05188334c32d023a69b6da79687ff8fa7485e7499db57046
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 TNXB WNT2

1.10e-05188334e54e09d34e263d5709c337914809e61e74e20591
ToppCelldroplet-Fat-Scat-21m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 TNXB WNT2

1.10e-051883347fc9810ab14354cb512e2b1285562009c10203f5
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 TNXB WNT2 WNT11

1.10e-051883341cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SNED1 FBN1 TNXB WNT2

1.10e-05188334409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SNED1 FBN1 TNXB SEMA3E

1.10e-051883340e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 TNXB WNT2

1.12e-051893341821ae4a6e37ee4c6308071883f3f447a7c53c53
ToppCellFibroblast-C|World / shred on cell class and cell subclass (v4)

FBN1 FBN2 TNXB PEG3

1.12e-0518933458e0400fbab5a0755504275aef5cf7986149abab
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 TNXB WNT2

1.12e-051893341e4d7e8dc98b3d70351e6a6c2aaf9ca01f141b8f
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 TNXB WNT2

1.12e-051893341dc415ed41815f4296dafd8cf7f3e014c44db1db
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SNED1 FBN1 ACVR2A WNT2

1.12e-051893342a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FBN1 TNXB WNT2 SEMA3E

1.12e-05189334473b01c9162b12b90a617c600238436177a0d18d
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.12e-05189334bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.15e-05190334f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 FBN2 TNXB PEG3

1.15e-05190334947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.15e-05190334c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 FBN2 TNXB PEG3

1.17e-05191334db4943dd19207663fb9e27f8940fa4b06a933625
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SNED1 TNXB WNT2 PEG3

1.17e-0519133414057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.19e-05192334de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.19e-0519233425492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 TNXB PEG3

1.19e-05192334cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 TNXB PEG3

1.19e-0519233429bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCellPND28-Mesenchymal-Mesenchymal_structural|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 TNXB WNT2

1.22e-05193334ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBD EDIL3 TNXB NOTCH1

1.22e-05193334daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 TNXB WNT2

1.22e-0519333430481fb01c7acf85beae10213f038da86bed6777
ToppCellMesenchymal_cells-Endosteal_fibro.|Mesenchymal_cells / Lineage and Cell class

THBD FBN1 TNXB WNT2

1.24e-051943349a4b5de4d1d8a0aa76fed7b36548ea628f3009cc
ToppCellMesenchymal_cells-Endosteal_fibro.|World / Lineage and Cell class

THBD FBN1 TNXB WNT2

1.27e-05195334d53974d1866e23c894ffd492ea11d20422919b11
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.27e-05195334b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.27e-051953341c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.27e-051953343a0cad69cfc150a27a0666f612f5294c817197d7
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.27e-051953341f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.27e-0519533410f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCellPND10-Mesenchymal-Mesenchymal_structural|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.27e-0519533411d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCellPND07-Mesenchymal-Mesenchymal_structural|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.27e-051953342f9a274b26fc528a85f50933ec2f4db1dc9da0ca
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 FBN1 WNT2 PEG3

1.27e-051953342b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCelldistal-Epithelial-Proximal_Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SNED1 ASB2 MEGF10 ZNF551

1.29e-05196334c102b28d5d1d90b9f7024cb51114276354be26a5
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBD FBN1 TNXB SEMA3E

1.29e-05196334ed6047b48b6a96baa6a90c7af784e7c34b32824d
ToppCelldistal-Epithelial-Proximal_Basal-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SNED1 ASB2 MEGF10 ZNF551

1.29e-05196334a543d4623096cb3f9170dbf7af52381e77aa435e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN1 ACVR2A TNXB PEG3

1.32e-051973346b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCelldroplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD FBN1 TNXB WNT2

1.35e-05198334d4f74320ea6c1a7e568ee5bc48bb66cb45e1004d
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN1 TNXB WNT2 PEG3

1.37e-05199334bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBD FBN1 EDIL3 TNXB

1.37e-05199334a272c54baf8de59c0f259e6498d144a0de8d8924
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FBN1 EDIL3 TNXB MEGF10

1.37e-0519933407b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

THBD FBN1 EDIL3 TNXB

1.37e-0519933456d72da6a5fab9cbb2975fe6f87a631debaba6a8
ToppCellBiopsy_Other_PF-Mesenchymal-Myofibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

FBN1 EDIL3 TNXB WNT2

1.40e-05200334e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SNED1 FBN1 TNXB SEMA3E

1.40e-05200334747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 FBN1 EDIL3 TNXB

1.40e-05200334c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell5'-Adult-SmallIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN1 EDIL3 TNXB SEMA3E

1.40e-05200334a637281d91e95734ee4f8510b3780e0272b16fda
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 ESM1 THBD TNXB

1.40e-05200334b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCellBiopsy_IPF-Mesenchymal-HAS1_High_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

FBN1 EDIL3 TNXB WNT2

1.40e-05200334d02e256b5d65a5c982ba5696bc7e077281ca3e24
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SNED1 FBN1 TNXB SEMA3E

1.40e-05200334de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGF TNXB WNT2

1.07e-04125333b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBD MUC5AC PEG3

2.11e-041573332c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SNED1 THBD WNT11

2.11e-04157333b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBD SERPINB9 NOTCH1

2.11e-04157333c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 WNT2 MEGF10

2.19e-04159333d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 TNXB PEG3

2.19e-041593337ed659163f45e0c4df4782997c0786900c8186c8
ToppCelldroplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB2 EGF MEGF10

2.27e-04161333f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCelldroplet-Lung-nan-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB2 EGF MEGF10

2.27e-04161333110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 ESM1 NOTCH1

2.35e-0416333373c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 MUC5AC TNXB

2.44e-04165333f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 TNXB PEG3

2.44e-041653334e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

FBN1 ASB2 TNXB

2.52e-04167333d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

FBN1 TNXB WNT2

2.61e-041693338ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN1 FBN2 EDIL3

2.61e-04169333c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBD FBN1 TNXB

2.66e-04170333dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBD FBN1 TNXB

2.66e-041703336035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBD FBN1 TNXB

2.66e-04170333c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASB2 MEGF10 ZNF551

2.66e-04170333fed8e982d2ce234c59d4016432ed8941df36df27
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC LINC00471 PEG3

2.71e-04171333eddc5e05003382603ee49f74b9e2242a43021096
ToppCellBac-SEP-Myeloid-cDC1|Bac-SEP / Disease, Lineage and Cell Type

THBD NAA40 FBN1

2.80e-04173333f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN1 TNXB SEMA3E

2.80e-0417333311e95a60b5f6f07f27154a23203bac431e7528c6
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-4|TCGA-Adrenal / Sample_Type by Project: Shred V9

EHMT1 FBN2 TNXB

2.85e-0417433315e2b9f46404ff9575e149024b24cb17b50b02b5
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

THBD FBN1 TNXB

1.21e-0448223GAVISH_3CA_METAPROGRAM_FIBROBLASTS_PI16_POS
ComputationalAdhesion molecules.

FBN1 FBN2 TNXB WNT2

1.73e-04141224MODULE_122
DrugRgd Peptide

THBD FBN1 FBN2 EGF EDIL3 TNXB

9.06e-07239326CID000104802
DrugTAAD

FBN1 FBN2 ACVR2A

3.30e-0621323CID000133445
DrugUNC0642

EHMT1 EGF

1.15e-054322ctd:C000621860
Drugrosavin

FBN1 FBN2 EGF

1.22e-0532323ctd:C529148
Drugquinocetone

THBD FBN1 FBN2 MEGF10 PEG3

2.33e-05248325ctd:C502851
DrugYM 155

EHMT1 EGF

2.86e-056322ctd:C523798
DrugTAPI-2

EGF MUC5AC

4.00e-057322ctd:C099410
Drug4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid

MUC2 MUC5AC

5.33e-058322ctd:C064545
Diseasecystitis (is_marker_for)

MUC2 MUC5AC

1.21e-062332DOID:1679 (is_marker_for)
Diseasesputum mucin-5B amount

MUC2 MUC5AC

3.64e-063332OBA_2050332
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2

3.64e-063332DOID:65 (implicated_via_orthology)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

7.27e-064332DOID:0060249 (is_implicated_in)
Diseasemucinous adenocarcinoma (is_marker_for)

MUC2 MUC5AC

1.21e-055332DOID:3030 (is_marker_for)
Diseasepneumonia

ACVR2A MUC2 MUC5AC

2.00e-0547333EFO_0003106
Diseaseeosinophil count

SETD2 ACVR2A ASB2 MUC2 MUC5AC TNXB ZNF177 NOTCH1 WNT11

2.64e-051488339EFO_0004842
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2 NOTCH1

2.87e-0553333C4707243
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

MUC2 MUC5AC

4.35e-059332EFO_0009824
Diseasecholangiocarcinoma (is_marker_for)

MUC2 MUC5AC NOTCH1

5.07e-0564333DOID:4947 (is_marker_for)
DiseaseMarfan syndrome (implicated_via_orthology)

FBN1 ACVR2A

5.43e-0510332DOID:14323 (implicated_via_orthology)
DiseaseReplication Error Phenotype

SETD2 ACVR2A

1.26e-0415332C1721098
DiseaseMicrosatellite Instability

SETD2 ACVR2A

1.26e-0415332C0920269
Diseaseischemia (biomarker_via_orthology)

THBD MUC2

1.84e-0418332DOID:326 (biomarker_via_orthology)
Diseaseneurotic disorder

ACVR2A TNXB SEMA3E

1.97e-04101333EFO_0004257
Diseasepancreatic cancer (is_marker_for)

ACVR2A EGF MUC5AC

1.97e-04101333DOID:1793 (is_marker_for)
Diseaseascending aortic diameter

FBN1 FBN2 ACVR2A

5.14e-04140333EFO_0021787
Diseaserespiratory system disease

MUC2 MUC5AC WNT11

5.69e-04145333EFO_0000684
Diseaseliver cirrhosis (biomarker_via_orthology)

FBN1 MUC2

6.65e-0434332DOID:5082 (biomarker_via_orthology)
Diseasecervical cancer

WNT2 NOTCH1

6.65e-0434332C4048328
DiseaseUterine Cervical Neoplasm

WNT2 NOTCH1

7.05e-0435332C0007873
Diseaseschizophrenia (is_marker_for)

EGF ARPC1A

1.11e-0344332DOID:5419 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
MDLGCDGEPCFSCLY

ASB2

496

Q96Q27
DSPEVYFCCCEGNMC

ACVR2A

96

P27037
CRGFPMSGCELETSC

LINC00471

81

Q8N535
DCCPMLFNYDDRGCL

ARPC1A

266

Q92747
KSQCCPGFYESGEMC

MEGF10

91

Q96KG7
GYECACEPGYTGSMC

NOTCH1

661

P46531
MDGCFCPEGTVYDDI

MUC2

326

Q02817
CDGCDAGYHMECLDP

PHRF1

201

Q9P1Y6
YTEVEECGCMGRRCP

MUC5AC

5606

P98088
MSGCCGEDCSYEILS

NAA40

201

Q86UY6
DFGAMPYVCDECGRS

PEG3

446

Q9GZU2
PALQCCEGYRMCASF

FAM24B

66

Q8N5W8
CDMCDRGYHTFCVGL

PHF10

451

Q8WUB8
YSCECPGEFMGRNCQ

EDIL3

141

O43854
DQDDCAPVGCSMYAR

EGF

831

P01133
EGSYECSCQPGFALM

FBN1

1216

P35555
GYRCECDMGFVPSAD

FBN1

1426

P35555
DCPYGTFGMDCRETC

ESM1

101

Q9NQ30
GGECLYSMECYDPRT

KLHDC7B

411

Q96G42
DGSFRCECPMGYNLD

FBN2

2191

P35556
FRCMNTFGSYECTCP

FBN2

2266

P35556
CGYFCTAGNFMECQP

EHMT1

591

Q9H9B1
DQPGSYSCMCETGYR

THBD

301

P07204
DMLCAGSEGRDSCYG

PRSS29P

246

A6NIE9
DADQGYVCECPEGFM

SNED1

446

Q8TER0
YVCECPEGFMGLDCR

SNED1

451

Q8TER0
MDSCEVMCCGRGYDT

WNT2

301

P09544
RTHSGEMPYECSDCG

ZNF177

276

Q13360
FVVAECCMESGPRFC

SERPINB9

336

P50453
CDPGYTGDDCGMRSC

TNXB

266

P22105
EMPYQCSDCGKSFSC

ZNF551

416

Q7Z340
FDTCRGDSGGPLMCY

TMPRSS12

261

Q86WS5
MIECSSRCPNGDYCS

SETD2

1526

Q9BYW2
SDSCDLMCCGRGYNP

WNT11

306

O96014
MYGSACADCCLARDP

SEMA3E

521

O15041
GFSGMFCSDRCVEAC

ZAN

1446

Q9Y493