Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone phosphatase activity

EYA1 EYA2 EYA3

9.16e-083913GO:0140789
GeneOntologyMolecularFunctionhistone H2AXY142 phosphatase activity

EYA1 EYA2 EYA3

9.16e-083913GO:0140793
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

1.02e-0640915GO:0140662
GeneOntologyMolecularFunctionATP-dependent protein disaggregase activity

HSPA1A HSPA1B HSPA8

1.81e-066913GO:0140545
GeneOntologyMolecularFunctionC3HC4-type RING finger domain binding

HSPA1A HSPA1B HSPA8

1.81e-066913GO:0055131
GeneOntologyMolecularFunctionprotein folding chaperone

HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

2.07e-0573915GO:0044183
GeneOntologyMolecularFunctionunfolded protein binding

SRSF10 HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

2.41e-05126916GO:0051082
GeneOntologyMolecularFunctiondisordered domain specific binding

HSPA1A HSPA1B HSP90AB1 HSP90AB3P

2.94e-0539914GO:0097718
GeneOntologyMolecularFunctionprotein-containing complex destabilizing activity

HSPA1A HSPA1B HSPA8

4.00e-0515913GO:0140776
GeneOntologyMolecularFunctiondenatured protein binding

HSPA1A HSPA1B

6.14e-053912GO:0031249
GeneOntologyMolecularFunctiondeath receptor agonist activity

HSPA1A HSPA1B

2.04e-045912GO:0038177
GeneOntologyMolecularFunctionATP-dependent activity

PMS2 MYH11 UBA7 CHTF18 RNF213 HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

4.82e-046149110GO:0140657
GeneOntologyMolecularFunctiontranscription regulator inhibitor activity

HSPA1A HSPA1B TFDP1

5.86e-0436913GO:0140416
GeneOntologyMolecularFunctionheat shock protein binding

SACS HSPA1A HSPA1B HSPA8 HSP90AB1

9.01e-04163915GO:0031072
GeneOntologyMolecularFunctionATP hydrolysis activity

PMS2 CHTF18 RNF213 HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

9.11e-04441918GO:0016887
GeneOntologyMolecularFunctionpyrophosphatase activity

PRUNE2 PMS2 RHOD CHTF18 RNF213 HSPA1A HSPA1B ENTPD4 HSPA8 HSP90AB1 HSP90AB3P

1.49e-038399111GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

PRUNE2 PMS2 RHOD CHTF18 RNF213 HSPA1A HSPA1B ENTPD4 HSPA8 HSP90AB1 HSP90AB3P

1.50e-038409111GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

PRUNE2 PMS2 RHOD CHTF18 RNF213 HSPA1A HSPA1B ENTPD4 HSPA8 HSP90AB1 HSP90AB3P

1.50e-038409111GO:0016818
GeneOntologyMolecularFunctionprotein domain specific binding

SRSF10 CAPN7 SH3KBP1 PRKDC HSPA1A HSPA1B HSPA8 TFDP1 TFDP2 HSP90AB1 HSP90AB3P

2.07e-038759111GO:0019904
GeneOntologyMolecularFunctiondiacylglycerol-dependent serine/threonine kinase activity

SMG1 PRKCH

2.36e-0316912GO:0004697
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

PMS2 RHOD CHTF18 RNF213 HSPA1A HSPA1B ENTPD4 HSPA8 HSP90AB1 HSP90AB3P

2.76e-037759110GO:0017111
GeneOntologyMolecularFunctionmisfolded protein binding

HSPA1A HSPA1B

3.00e-0318912GO:0051787
GeneOntologyMolecularFunctionhistone modifying activity

SETDB1 PRKDC EYA1 EYA2 EYA3

3.97e-03229915GO:0140993
GeneOntologyMolecularFunctiondeath receptor activity

HSPA1A HSPA1B

4.08e-0321912GO:0005035
GeneOntologyMolecularFunctionubiquitin protein ligase binding

CKB SH3KBP1 HSPA1A HSPA1B HSPA8 HSP90AB1

4.43e-03337916GO:0031625
GeneOntologyMolecularFunctioncadherin binding

FLNB DIAPH3 HSPA1A CDH8 HSPA8 HSP90AB1

4.56e-03339916GO:0045296
GeneOntologyBiologicalProcessresponse to temperature stimulus

HSBP1L1 ALDH18A1 HSPA1A HSPA1B CHRFAM7A CDH8 HSPA8 HSP90AB1 HSP90AB3P

3.48e-07208919GO:0009266
GeneOntologyBiologicalProcessnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

EYA1 EYA2 EYA3 HSPA1A HSPA1B

8.71e-0740915GO:2001240
GeneOntologyBiologicalProcessnegative regulation of signal transduction in absence of ligand

EYA1 EYA2 EYA3 HSPA1A HSPA1B

8.71e-0740915GO:1901099
GeneOntologyBiologicalProcesscellular response to heat

HSBP1L1 HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

1.55e-0681916GO:0034605
GeneOntologyBiologicalProcesscellular heat acclimation

HSBP1L1 HSPA1A HSPA1B

1.65e-066913GO:0070370
GeneOntologyBiologicalProcessheat acclimation

HSBP1L1 HSPA1A HSPA1B

2.87e-067913GO:0010286
GeneOntologyBiologicalProcessregulation of extrinsic apoptotic signaling pathway in absence of ligand

EYA1 EYA2 EYA3 HSPA1A HSPA1B

3.99e-0654915GO:2001239
GeneOntologyBiologicalProcesstelomere maintenance

SMG1 NFRKB NBN PRKDC HSPA1A HSPA1B HSP90AB1

9.56e-06168917GO:0000723
GeneOntologyBiologicalProcessresponse to heat

HSBP1L1 HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

1.60e-05121916GO:0009408
GeneOntologyBiologicalProcesspositive regulation of DNA metabolic process

PMS2 NFATC1 CHTF18 NFRKB NBN PRKDC EYA1 EYA2 EYA3

1.64e-05333919GO:0051054
GeneOntologyBiologicalProcessnegative regulation of inclusion body assembly

SACS HSPA1A HSPA1B

1.78e-0512913GO:0090084
GeneOntologyBiologicalProcesstelomere organization

SMG1 NFRKB NBN PRKDC HSPA1A HSPA1B HSP90AB1

2.86e-05199917GO:0032200
GeneOntologyBiologicalProcessextrinsic apoptotic signaling pathway in absence of ligand

EYA1 EYA2 EYA3 HSPA1A HSPA1B

3.12e-0582915GO:0097192
GeneOntologyBiologicalProcesssignal transduction in absence of ligand

EYA1 EYA2 EYA3 HSPA1A HSPA1B

3.51e-0584915GO:0038034
GeneOntologyBiologicalProcessregulation of DNA metabolic process

SMG1 PMS2 NFATC1 CHTF18 NFRKB NBN PRKDC EYA1 EYA2 EYA3 TFDP1

3.80e-055649111GO:0051052
GeneOntologyBiologicalProcesspositive regulation of DNA repair

NFRKB NBN PRKDC EYA1 EYA2 EYA3

4.11e-05143916GO:0045739
GeneOntologyBiologicalProcesssupramolecular fiber organization

KRT7 MYH11 RHOD VPS33B SH3KBP1 AKAP13 RP1 DIAPH3 PLEK HSPA1A HSPA1B CHRFAM7A HSPA8 HSP90AB1

7.43e-059579114GO:0097435
GeneOntologyBiologicalProcessnegative regulation of protein modification process

IVNS1ABP IBTK SLC8A1 COPS9 PRKCH PRKDC SMCR8 HSPA1A HSPA1B CHRFAM7A

8.65e-055129110GO:0031400
GeneOntologyBiologicalProcessregulation of inclusion body assembly

SACS HSPA1A HSPA1B

1.04e-0421913GO:0090083
GeneOntologyBiologicalProcessviral life cycle

SETDB1 LAMP3 HS3ST5 NBN HSPA1A HSPA1B HSPA8 HSP90AB1

1.30e-04340918GO:0019058
GeneOntologyBiologicalProcessnegative regulation of extrinsic apoptotic signaling pathway

EYA1 EYA2 EYA3 HSPA1A HSPA1B

1.44e-04113915GO:2001237
GeneOntologyBiologicalProcesschromosome organization

SMG1 SETDB1 HECW2 CHTF18 NFRKB NBN PRKDC HSPA1A HSPA1B STAG2 HSP90AB1

2.15e-046869111GO:0051276
GeneOntologyBiologicalProcessregulation of protein stability

NAA15 PRKDC HSPA1A HSPA1B HSPA8 NAA16 HSP90AB1 HSP90AB3P

2.23e-04368918GO:0031647
GeneOntologyBiologicalProcessDNA metabolic process

SMG1 PMS2 NFATC1 CHTF18 NFRKB NBN PRKDC EYA1 EYA2 EYA3 HSPA1A HSPA1B TFDP1 HSP90AB1

2.65e-0410819114GO:0006259
GeneOntologyBiologicalProcessresponse to abiotic stimulus

SLC8A1 COPS9 CACNA2D4 HSBP1L1 ALDH18A1 RP1 PRKDC EYA1 EYA3 HSPA1A HSPA1B CHRFAM7A CDH8 HSPA8 HSP90AB1 HSP90AB3P

2.78e-0413619116GO:0009628
GeneOntologyBiologicalProcessprotein-containing complex disassembly

VPS33B APEH RP1 DIAPH3 PLEK SMCR8 HSPA8

3.05e-04291917GO:0032984
GeneOntologyBiologicalProcessprotein refolding

HSPA1A HSPA1B HSPA8

3.09e-0430913GO:0042026
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

3.99e-047912GO:0070434
GeneOntologyBiologicalProcessN-terminal peptidyl-methionine acetylation

NAA15 NAA16

3.99e-047912GO:0017196
GeneOntologyBiologicalProcessinclusion body assembly

SACS HSPA1A HSPA1B

4.12e-0433913GO:0070841
GeneOntologyBiologicalProcesspeptidyl-serine phosphorylation

STK32A SMG1 STK32B PRKCH PRKDC STK32C CHRFAM7A

4.21e-04307917GO:0018105
GeneOntologyBiologicalProcessnegative regulation of apoptotic process

IVNS1ABP CACNA1A NAA15 LAMP3 PRKCH PRKDC EYA1 EYA2 EYA3 HSPA1A HSPA1B HSPA8 NAA16 HSP90AB1

4.27e-0411339114GO:0043066
GeneOntologyBiologicalProcesschaperone-mediated protein folding

HSPA1A HSPA1B HSPA8 HSP90AB1

4.34e-0480914GO:0061077
GeneOntologyBiologicalProcessorganelle assembly

MYH11 VPS33B SPEF2 RNF213 AKAP13 RP1 PRKDC DIAPH3 CSMD2 SMCR8 HSPA1A HSPA1B STAG2 NME8

4.46e-0411389114GO:0070925
GeneOntologyBiologicalProcesschaperone cofactor-dependent protein refolding

HSPA1A HSPA1B HSPA8

4.91e-0435913GO:0051085
GeneOntologyBiologicalProcessbiological process involved in interaction with host

LAMP3 HS3ST5 NBN HSPA1A HSPA1B HSP90AB1

5.21e-04228916GO:0051701
GeneOntologyBiologicalProcesspeptidyl-serine modification

STK32A SMG1 STK32B PRKCH PRKDC STK32C CHRFAM7A

5.28e-04319917GO:0018209
GeneOntologyBiologicalProcesspositive regulation of microtubule nucleation

HSPA1A HSPA1B

5.30e-048912GO:0090063
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

HSPA1A HSPA1B

5.30e-048912GO:0070426
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

IVNS1ABP KLHL2 RNF220 COPS9 UBA7 HECW2 RNF213 NBN EYA1 HSPA1A HSPA1B HSP90AB1

5.46e-048939112GO:0032446
GeneOntologyBiologicalProcessDNA repair

SMG1 PMS2 NFRKB NBN PRKDC EYA1 EYA2 EYA3 HSPA1A HSPA1B

5.70e-046489110GO:0006281
GeneOntologyBiologicalProcesspositive regulation of erythrocyte differentiation

PRKDC HSPA1A HSPA1B

5.79e-0437913GO:0045648
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

IVNS1ABP CACNA1A NAA15 LAMP3 PRKCH PRKDC EYA1 EYA2 EYA3 HSPA1A HSPA1B HSPA8 NAA16 HSP90AB1

5.92e-0411719114GO:0043069
GeneOntologyBiologicalProcessregulation of DNA repair

NFRKB NBN PRKDC EYA1 EYA2 EYA3

5.97e-04234916GO:0006282
GeneOntologyBiologicalProcessdouble-strand break repair via alternative nonhomologous end joining

NBN PRKDC

6.79e-049912GO:0097681
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

AKAP13 RP1 DIAPH3 PLEK HSPA1A HSPA1B CHRFAM7A HSPA8

7.08e-04438918GO:1902903
GeneOntologyBiologicalProcessprotein stabilization

NAA15 HSPA1A HSPA1B NAA16 HSP90AB1 HSP90AB3P

7.27e-04243916GO:0050821
GeneOntologyBiologicalProcessprotein folding

SACS HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

7.75e-04246916GO:0006457
GeneOntologyBiologicalProcess'de novo' post-translational protein folding

HSPA1A HSPA1B HSPA8

7.84e-0441913GO:0051084
GeneOntologyBiologicalProcessmuscle tissue development

FLNB SEMA3C SLC8A1 MYH11 ALDH1A2 AKAP13 EYA1 EYA2 HSPA8

7.96e-04558919GO:0060537
GeneOntologyBiologicalProcessstriated muscle tissue development

SEMA3C SLC8A1 MYH11 ALDH1A2 AKAP13 EYA1 EYA2

8.96e-04349917GO:0014706
GeneOntologyBiologicalProcesssymbiont entry into host cell

LAMP3 HS3ST5 NBN HSPA1A HSPA1B

9.17e-04169915GO:0046718
GeneOntologyBiologicalProcessbiological process involved in symbiotic interaction

LAMP3 HS3ST5 NBN HSPA1A HSPA1B HSPA8 HSP90AB1

9.27e-04351917GO:0044403
GeneOntologyBiologicalProcessnegative regulation of protein metabolic process

IVNS1ABP IBTK SLC8A1 COPS9 CST9L LAMP3 PRKCH PRKDC SMCR8 HSPA1A HSPA1B CHRFAM7A HSP90AB1

9.50e-0410889113GO:0051248
GeneOntologyBiologicalProcessnegative regulation of protein modification by small protein conjugation or removal

IVNS1ABP COPS9 HSPA1A HSPA1B

1.01e-03100914GO:1903321
GeneOntologyBiologicalProcessDNA damage response

SMG1 PLA2R1 PMS2 UBA7 NFRKB NBN PRKDC EYA1 EYA2 EYA3 HSPA1A HSPA1B

1.02e-039599112GO:0006974
GeneOntologyBiologicalProcessviral process

SETDB1 LAMP3 HS3ST5 NBN HSPA1A HSPA1B HSPA8 HSP90AB1

1.03e-03464918GO:0016032
GeneOntologyBiologicalProcessregulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

1.03e-0311912GO:0070432
GeneOntologyBiologicalProcess'de novo' protein folding

HSPA1A HSPA1B HSPA8

1.10e-0346913GO:0006458
GeneOntologyBiologicalProcesssymbiont entry into host

LAMP3 HS3ST5 NBN HSPA1A HSPA1B

1.10e-03176915GO:0044409
GeneOntologyBiologicalProcessnegative regulation of post-translational protein modification

IVNS1ABP COPS9 HSPA1A HSPA1B

1.16e-03104914GO:1901874
GeneOntologyBiologicalProcessmembraneless organelle assembly

MYH11 RNF213 AKAP13 PRKDC DIAPH3 HSPA1A HSPA1B STAG2

1.19e-03475918GO:0140694
GeneOntologyBiologicalProcessregulation of extrinsic apoptotic signaling pathway

EYA1 EYA2 EYA3 HSPA1A HSPA1B

1.25e-03181915GO:2001236
GeneOntologyCellularComponentCOP9 signalosome

COPS9 HSPA1A HSPA1B HSP90AB1

2.03e-0538894GO:0008180
GeneOntologyCellularComponentnuclear protein-containing complex

IVNS1ABP PMS2 COPS9 CPSF6 CHTF18 NFRKB U2AF1L4 NBN ICE1 PRKDC SNRPB2 HSPA1A HSPA1B HSPA8 TFDP1 TFDP2 HSP90AB1

6.12e-0513778917GO:0140513
GeneOntologyCellularComponentNatA complex

NAA15 NAA16

1.78e-045892GO:0031415
GeneOntologyCellularComponentficolin-1-rich granule lumen

APEH HSPA1A HSPA1B HSPA8 HSP90AB1

1.89e-04124895GO:1904813
GeneOntologyCellularComponentpostsynaptic membrane

CACNA1A SLC8A1 PCDHB13 PCDHB8 CSMD2 CHRFAM7A UTRN HSPA8

3.33e-04405898GO:0045211
GeneOntologyCellularComponentnuclear body

SRSF10 NAA15 NFATC1 CPSF6 U2AF1L4 NBN ICE1 EYA1 SNRPB2 HSPA1A HSPA1B NME8

4.36e-049038912GO:0016604
GeneOntologyCellularComponentinclusion body

NBN HSPA1A HSPA1B HSP90AB1

5.93e-0490894GO:0016234
GeneOntologyCellularComponentN-terminal protein acetyltransferase complex

NAA15 NAA16

7.89e-0410892GO:0031414
GeneOntologyCellularComponentsynaptic membrane

CACNA1A SLC8A1 PCDHB13 PCDHB8 CSMD2 CHRFAM7A UTRN CDH8 HSPA8

8.41e-04583899GO:0097060
GeneOntologyCellularComponentphotoreceptor connecting cilium

PCDHB13 PCDHB8 RP1

1.12e-0348893GO:0032391
GeneOntologyCellularComponentficolin-1-rich granule

APEH HSPA1A HSPA1B HSPA8 HSP90AB1

1.17e-03185895GO:0101002
GeneOntologyCellularComponentmelanosome

MYH11 GANAB HSPA8 HSP90AB1

1.39e-03113894GO:0042470
GeneOntologyCellularComponentpigment granule

MYH11 GANAB HSPA8 HSP90AB1

1.39e-03113894GO:0048770
GeneOntologyCellularComponentactin filament bundle

KLHL2 FLNB MYH11 DIAPH3

1.63e-03118894GO:0032432
GeneOntologyCellularComponentperinuclear region of cytoplasm

ALDH1A2 NFATC1 VPS33B LAMP3 FSD2 AKAP13 HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

2.02e-039348911GO:0048471
DomainEYA_fam

EYA1 EYA2 EYA3

4.31e-074903IPR028472
DomainEYA_dom

EYA1 EYA2 EYA3

4.31e-074903IPR006545
DomainNatA_aux_su

NAA15 NAA16

2.30e-052902IPR021183
DomainNARP1

NAA15 NAA16

2.30e-052902PF12569
DomainBTB-kelch_protein

IVNS1ABP KLHL2 KLHL33 KLHL26

5.39e-0543904IPR017096
DomainHSP70

HSPA1A HSPA1B HSPA8

5.79e-0516903PF00012
DomainTransc_factor_DP_C

TFDP1 TFDP2

6.87e-053902IPR014889
DomainDP

TFDP1 TFDP2

6.87e-053902PF08781
DomainDP

TFDP1 TFDP2

6.87e-053902SM01138
DomainTranscrpt_fac_DP

TFDP1 TFDP2

6.87e-053902IPR015648
DomainHSP70_2

HSPA1A HSPA1B HSPA8

7.01e-0517903PS00329
DomainHSP70_3

HSPA1A HSPA1B HSPA8

7.01e-0517903PS01036
DomainHSP70_1

HSPA1A HSPA1B HSPA8

7.01e-0517903PS00297
DomainHsp_70_fam

HSPA1A HSPA1B HSPA8

8.38e-0518903IPR013126
DomainHATPase_C

PMS2 SACS HSP90AB1

1.35e-0421903IPR003594
DomainKelch

IVNS1ABP KLHL2 KLHL33 KLHL26

1.75e-0458904SM00612
DomainBACK

IVNS1ABP KLHL2 KLHL33 KLHL26

2.00e-0460904SM00875
DomainBACK

IVNS1ABP KLHL2 KLHL33 KLHL26

2.13e-0461904PF07707
DomainBACK

IVNS1ABP KLHL2 KLHL33 KLHL26

2.13e-0461904IPR011705
DomainFATC

SMG1 PRKDC

2.27e-045902PF02260
Domain-

IVNS1ABP KLHL2 KLHL26

2.91e-04279032.130.10.80
DomainFAT

SMG1 PRKDC

3.40e-046902PS51189
DomainFATC

SMG1 PRKDC

3.40e-046902PS51190
DomainFATC_dom

SMG1 PRKDC

3.40e-046902IPR003152
DomainPIK_FAT

SMG1 PRKDC

3.40e-046902IPR014009
DomainFATC

SMG1 PRKDC

3.40e-046902SM01343
DomainKelch_1

IVNS1ABP KLHL2 KLHL33 KLHL26

3.63e-0470904PF01344
DomainKelch_1

IVNS1ABP KLHL2 KLHL33 KLHL26

3.63e-0470904IPR006652
DomainGal_Oxidase_b-propeller

IVNS1ABP KLHL2 KLHL26

5.81e-0434903IPR015916
DomainBTB

IVNS1ABP KLHL2 IBTK KLHL33 KLHL26

1.06e-03160905PS50097
DomainE2F_TDP

TFDP1 TFDP2

1.23e-0311902PF02319
DomainE2F_TDP

TFDP1 TFDP2

1.23e-0311902SM01372
DomainE2F_WHTH_DNA-bd_dom

TFDP1 TFDP2

1.23e-0311902IPR003316
Domain-

HSPA1A HSPA8

1.47e-03129022.60.34.10
DomainHSP70_peptide-bd

HSPA1A HSPA8

1.47e-0312902IPR029047
Domain-

HSPA1A HSPA8

1.73e-03139021.20.1270.10
DomainHeat_shock_70_CS

HSPA1A HSPA8

1.73e-0313902IPR018181
DomainHSP70_C

HSPA1A HSPA8

1.73e-0313902IPR029048
DomainSEA

TMPRSS15 IMPG2

2.01e-0314902SM00200
DomainSKP1/BTB/POZ

IVNS1ABP KLHL2 IBTK KLHL33 KLHL26

2.21e-03189905IPR011333
Domain-

TMPRSS15 IMPG2

2.31e-03159023.30.70.960
DomainPI3/4_kinase_CS

SMG1 PRKDC

2.31e-0315902IPR018936
Domain-

SMG1 PRKDC

2.64e-03169021.10.1070.11
DomainPI3Kc

SMG1 PRKDC

2.64e-0316902SM00146
DomainPI3/4_kinase_cat_dom

SMG1 PRKDC

3.34e-0318902IPR000403
DomainPI3_PI4_kinase

SMG1 PRKDC

3.34e-0318902PF00454
DomainPI3_4_KINASE_3

SMG1 PRKDC

3.34e-0318902PS50290
DomainPI3_4_KINASE_1

SMG1 PRKDC

3.34e-0318902PS00915
DomainPI3_4_KINASE_2

SMG1 PRKDC

3.34e-0318902PS00916
DomainHATPase_c

PMS2 HSP90AB1

3.34e-0318902SM00387
DomainBTB

IVNS1ABP KLHL2 IBTK KLHL26

3.71e-03131904PF00651
DomainHATPase_c

PMS2 HSP90AB1

3.72e-0319902PF02518
DomainAld_DH_C

ALDH1A2 ALDH18A1

3.72e-0319902IPR016163
DomainAld_DH_N

ALDH1A2 ALDH18A1

3.72e-0319902IPR016162
DomainAld_DH/histidinol_DH

ALDH1A2 ALDH18A1

3.72e-0319902IPR016161
Domain-

ALDH1A2 ALDH18A1

3.72e-03199023.40.605.10
DomainAldedh

ALDH1A2 ALDH18A1

3.72e-0319902PF00171
DomainAldehyde_DH_dom

ALDH1A2 ALDH18A1

3.72e-0319902IPR015590
Domain-

ALDH1A2 ALDH18A1

3.72e-03199023.40.309.10
DomainSemaphorin

SEMA6C SEMA3C

4.12e-0320902IPR027231
Domain-

SACS HSP90AB1

4.12e-03209023.30.565.10
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA8 HSP90AB1

4.83e-0713744MM14952
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA8 HSP90AB1

5.74e-0623744MM14953
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA8 HSP90AB1

1.30e-0528744M27254
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA8 HSP90AB1

4.51e-0538744M27255
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

FLNB UBA7 HSPA1A HSPA1B HSPA8

1.33e-0494745MM14515
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

HSPA1A HSPA1B HSPA8 HSP90AB1

1.57e-0452744MM14949
PathwayREACTOME_DNA_REPAIR

PMS2 UBA7 NFRKB NBN PRKDC EYA1 EYA2 EYA3

1.75e-04301748MM15433
PathwayREACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE

NBN EYA1 EYA2 EYA3

2.24e-0457744MM15298
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

HSPA1A HSPA1B HSPA8 HSP90AB1

2.24e-0457744M27251
PathwayREACTOME_ACTIVATION_OF_NOXA_AND_TRANSLOCATION_TO_MITOCHONDRIA

TFDP1 TFDP2

2.69e-045742M26903
PathwayWP_MAPK_SIGNALING

CACNA1A FLNB CACNA2D4 NFATC1 HSPA1A HSPA1B HSPA8

3.01e-04246747M39597
PathwayREACTOME_DNA_REPAIR

PMS2 UBA7 NFRKB NBN PRKDC EYA1 EYA2 EYA3

3.39e-04332748M15434
PathwayREACTOME_BACTERIAL_INFECTION_PATHWAYS

VPS33B SH3KBP1 RNF213 HSP90AB1

5.21e-0471744M48033
PathwayKEGG_SPLICEOSOME

SRSF10 SNRPB2 HSPA1A HSPA1B HSPA8

5.37e-04127745M2044
PathwayREACTOME_HSF1_ACTIVATION

HSPA1A HSPA1B HSP90AB1

5.62e-0431743M27252
PathwayREACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE

NBN EYA1 EYA2 EYA3

7.44e-0478744M27589
PathwayREACTOME_INTERFERON_SIGNALING

FLNB UBA7 HSPA1A HSPA1B HSPA8

7.84e-04138745MM15635
PathwayREACTOME_ACTIVATION_OF_PUMA_AND_TRANSLOCATION_TO_MITOCHONDRIA

TFDP1 TFDP2

9.56e-049742M26946
PathwayREACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR

NBN PRKDC EYA1 EYA2 EYA3

1.01e-03146745MM15292
Pubmed

Function and regulation of heat shock factor 2 during mouse embryogenesis.

HSPA1A HSPA1B HSPA8 HSP90AB1

3.18e-0989249122205
Pubmed

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.

SETDB1 HSPA1A HSPA1B UTRN

3.18e-09892422495301
Pubmed

Electrophoretic and immunocytochemical analysis of Hsp72 and Hsp73 expression in heat-stressed mouse testis and epididymis.

HSPA1A HSPA1B HSPA8

1.79e-08392323352621
Pubmed

A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.

EYA1 EYA2 EYA3

1.79e-0839239020840
Pubmed

Stored of Hsp72/Hsp73 in germinal vesicle-stage mouse oocytes.

HSPA1A HSPA1B HSPA8

1.79e-08392315129916
Pubmed

Eyes absent represents a class of protein tyrosine phosphatases.

EYA1 EYA2 EYA3

1.79e-08392314628052
Pubmed

Functional analysis of HSPA1A and HSPA8 in parturition.

HSPA1A HSPA1B HSPA8

1.79e-08392328025138
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

CKB FLNB SRSF10 NAA15 CPSF6 CHTF18 SNRPB2 HSPA1A UTRN HSPA8 HSP90AB1 HSP90AB3P

1.96e-08538921228524877
Pubmed

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.

CKB SETDB1 APEH PRKDC HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

2.81e-0825692935777956
Pubmed

BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites.

CKB GANAB ALDH18A1 PRKDC HSPA8 HSP90AB1

4.29e-087392632347575
Pubmed

Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.

HSPA1A HSPA1B HSPA8

7.15e-08492318299791
Pubmed

Misexpression of the eyes absent family triggers the apoptotic program.

EYA1 EYA2 EYA3

7.15e-08492311700312
Pubmed

Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.

HSPA1A HSPA1B HSPA8

7.15e-08492322956628
Pubmed

Upregulation of the constitutively expressed HSC70 by KLF4.

HSPA1A HSPA1B HSPA8

7.15e-08492318379898
Pubmed

Clathrin facilitates the morphogenesis of retrovirus particles.

HSPA1A HSPA1B HSPA8 HSP90AB1

8.14e-081692421738476
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

CKB FLNB KRT7 GANAB NAA15 CPSF6 CHTF18 U2AF1L4 ALDH18A1 AKAP13 PRKDC DIAPH3 SNRPB2 HSPA1A STAG2 HSPA8 HSP90AB1

1.63e-071415921728515276
Pubmed

Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya.

EYA1 EYA2 EYA3

1.78e-07592310490620
Pubmed

A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing.

HSPA1A HSPA1B HSPA8

1.78e-07592311584023
Pubmed

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

HSPA1A HSPA1B HSPA8

1.78e-07592316906134
Pubmed

Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode.

EYA1 EYA2 EYA3

1.78e-0759239006082
Pubmed

HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain.

HSPA1A HSPA1B HSPA8

1.78e-07592317182002
Pubmed

A screen for deubiquitinating enzymes involved in the Gâ‚‚/M checkpoint identifies USP50 as a regulator of HSP90-dependent Wee1 stability.

HSPA1A HSPA8 HSP90AB1

1.78e-07592320930503
Pubmed

Eyes absent: a gene family found in several metazoan phyla.

EYA1 EYA2 EYA3

1.78e-0759239195991
Pubmed

A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.

HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

2.48e-075192536896912
Pubmed

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.

CKB COPS9 SRSF10 GANAB PRKDC HSPA1A HSPA8 HSP90AB1

2.93e-0724492830349055
Pubmed

Metallothionein-3 is a component of a multiprotein complex in the mouse brain.

CKB HSPA1B HSP90AB1

3.56e-07692317018872
Pubmed

Genetic aspects of the hsp70 multigene family in vertebrates.

HSPA1A HSPA1B HSPA8

3.56e-0769237988674
Pubmed

Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.

HSPA1A HSPA1B HSPA8

3.56e-07692315963462
Pubmed

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

HSPA1A HSPA1B HSPA8

3.56e-0769239305631
Pubmed

Identification of mouse brain proteins associated with isoform 3 of metallothionein.

CKB HSPA1B HSP90AB1

3.56e-07692315802640
Pubmed

RING finger protein RNF207, a novel regulator of cardiac excitation.

HSPA1A HSPA1B HSPA8

3.56e-07692325281747
Pubmed

Interaction of a Novel Chaperone PhLP2A With the Heat Shock Protein Hsp90.

HSPA1A HSPA1B HSP90AB1

3.56e-07692327496612
Pubmed

Heat shock factor 2 is activated during mouse heart development.

HSPA1A HSPA1B HSPA8

3.56e-07692311032181
Pubmed

EYA4, a novel vertebrate gene related to Drosophila eyes absent.

EYA1 EYA2 EYA3

3.56e-0769239887327
Pubmed

KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.

CKB FLNB PRKDC HSPA1B HSPA8 HSP90AB1

3.58e-0710492636055981
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

SETDB1 NBN PRKDC HSPA1A HSPA8 HSP90AB1

4.01e-0710692619394292
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

IVNS1ABP KRT7 SRSF10 CPSF6 CAPN7 HSPA1A HSPA1B HSPA8 HSP90AB1

4.28e-0735392927545878
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

IVNS1ABP FLNB HECW2 ALDH18A1 RNF213 AKAP13 ICE1 PRKDC CSMD2 UTRN HSPA8 HSP90AB1

5.71e-07736921229676528
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

FLNB IBTK RNF213 PRKDC HSPA1B UTRN HSPA8 HSP90AB1

5.96e-0726892833024031
Pubmed

Fibroblast growth factor receptor 3 (FGFR3) is a strong heat shock protein 90 (Hsp90) client: implications for therapeutic manipulation.

HSPA1B HSPA8 HSP90AB1

6.22e-07792321487019
Pubmed

Nik-related kinase is targeted for proteasomal degradation by the chaperone-dependent ubiquitin ligase CHIP.

HSPA1A HSPA8 HSP90AB1

6.22e-07792332162334
Pubmed

Control of mRNA decay by heat shock-ubiquitin-proteasome pathway.

HSPA1A HSPA1B HSPA8

6.22e-07792310205060
Pubmed

Messenger RNA expression of heat shock proteins (HSPs) during ocular development.

HSPA1B HSPA8 HSP90AB1

6.22e-0779238974842
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

FLNB KRT7 MYH11 HSPA1A UTRN HSPA8 HSP90AB1

7.97e-0719192733762435
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

CKB GANAB ALDH18A1 PRKDC HSPA1A HSPA8 HSP90AB1

9.81e-0719792731620119
Pubmed

A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter.

HSPA1A HSPA8 HSP90AB1

9.94e-07892325202009
Pubmed

CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.

CKB FLNB MYH11 PRKDC HSPA1A HSPA8 HSP90AB1 HSP90AB3P

1.02e-0628892831501420
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

CKB IBTK ALDH1A2 NAA15 CPSF6 NBN ICE1 PRKDC SMCR8 HSPA1A UTRN HSPA8 HSP90AB1

1.10e-06934921333916271
Pubmed

HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells.

CPSF6 HSPA1A HSPA1B UTRN HSPA8

1.23e-067092517342744
Pubmed

The ubiquitin ligase TRIM21 regulates mutant p53 accumulation and gain of function in cancer.

HSPA1A HSPA8 HSP90AB1

1.49e-06992336749630
Pubmed

Reciprocal regulation of human immunodeficiency virus-1 gene expression and replication by heat shock proteins 40 and 70.

HSPA1A HSPA1B HSPA8

1.49e-06992321763498
Pubmed

Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

HSPA1A HSPA1B HSPA8 HSP90AB1

1.56e-063292427437069
Pubmed

Proteomic analysis reveals novel binding partners of MIP-T3 in human cells.

CKB HSPA1A HSPA8 HSP90AB1

2.00e-063492420391533
Pubmed

Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.

HSPA1A HSPA1B HSPA8

2.12e-061092311932435
Pubmed

gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.

HSPA1A HSPA1B HSPA8

2.12e-061092312832005
Pubmed

Identification and characterization of SSTK, a serine/threonine protein kinase essential for male fertility.

HSPA1A HSPA8 HSP90AB1

2.12e-061092315870294
Pubmed

Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.

HSPA1A HSPA1B HSPA8

2.12e-06109237906708
Pubmed

Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation.

HSPA1A HSPA1B HSP90AB1

2.12e-061092316809764
Pubmed

Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.

HSPA1A HSPA1B HSPA8

2.12e-061092323921388
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

CKB FLNB MYH11 NAA15 PRKDC SNRPB2 HSPA1A HSPA1B UTRN HSPA8 HSP90AB1 HSP90AB3P

2.46e-06847921235235311
Pubmed

HSP90 Shapes the Consequences of Human Genetic Variation.

CHTF18 SMCR8 HSPA8 HSP90AB1

2.53e-063692428215707
Pubmed

ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.

HSPA1A HSPA1B HSPA8

2.91e-061192327708256
Pubmed

Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.

HSPA1A HSPA1B HSPA8

2.91e-061192324318877
Pubmed

Hsp and chaperone distribution during endochondral bone development in mouse embryo.

HSPA1B HSPA8 HSP90AB1

2.91e-06119239880236
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

FLNB SETDB1 SRSF10 NAA15 CPSF6 CHTF18 APEH ALDH18A1 RNF213 PRKDC SNRPB2 HSPA1A UTRN HSPA8 HSP90AB1

2.92e-061367921532687490
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

FLNB SETDB1 RNF213 PRKDC HSPA1A STAG2 HSPA8 HSP90AB1

2.94e-0633292832786267
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

CKB SRSF10 MYH11 CPSF6 ALDH18A1 PRKDC SNRPB2 HSPA1A HSPA1B HSPA8 HSP90AB1

3.01e-06714921128302793
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

FLNB MYH11 PRKDC HSPA1A STAG2 HSPA8 HSP90AB1

3.16e-0623592730258100
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

CKB GANAB NAA15 CPSF6 ALDH18A1 HSPA1A HSPA1B HSPA8 HSP90AB1

3.21e-0645192936168627
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

FLNB UBA7 GANAB HSPA1A HSPA8 HSP90AB1

3.30e-0615292616009940
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

CKB FLNB GANAB NAA15 ALDH18A1 PRKDC EYA3 SNRPB2 HSPA1A HSPA1B HSPA8 HSP90AB1

3.55e-06878921237223481
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

MYH11 GANAB CPSF6 HSPA1B HSPA8 HSP90AB1

3.84e-0615692630409884
Pubmed

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.

HSPA1A HSPA1B HSPA8

3.87e-061292312150907
Pubmed

HIV-1 viral protein R (Vpr) and its interactions with host cell.

HSPA1A HSPA1B HSPA8

3.87e-061292319275587
Pubmed

Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.

FLNB SRSF10 GANAB ALDH18A1 HSPA1A HSPA8

4.28e-0615992634537242
Pubmed

CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.

IVNS1ABP FLNB GANAB ALDH18A1 PRKDC SNRPB2 HSPA1B HSPA8 HSP90AB1

4.34e-0646892936042349
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

CKB FLNB KRT7 SEMA3C MYH11 GANAB CAPN7 APEH HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

4.85e-061070921323533145
Pubmed

A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.

HSPA1A HSPA1B HSPA8

5.03e-061392330792309
Pubmed

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

HSPA1A HSPA1B HSPA8

5.03e-061392327477512
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

FLNB KRT7 GANAB ALDH18A1 PRKDC HSPA1B UTRN HSPA8

5.33e-0636092833111431
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

SRSF10 AKAP13 PRKDC HSPA1A HSPA1B HSPA8 HSP90AB1

5.41e-0625592715324660
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

FLNB KRT7 CPSF6 PRKDC DIAPH3 HSPA1A HSPA8

5.55e-0625692733397691
Pubmed

SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.

MYH11 ALDH1A2 EYA1

6.38e-061492320110314
Pubmed

Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.

HSPA1A HSPA1B

6.92e-06292212411538
Pubmed

Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.

HSPA1A HSPA1B

6.92e-0629222868009
Pubmed

Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.

HSPA1A HSPA1B

6.92e-06292224328534
Pubmed

In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.

HSPA1A HSPA1B

6.92e-0629223786141
Pubmed

Processing of U14 small nucleolar RNA from three different introns of the mouse 70-kDa-cognate-heat-shock-protein pre-messenger RNA.

HSPA1B HSPA8

6.92e-0629227813466
Pubmed

Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.

HSPA1A HSPA1B

6.92e-06292226923070
Pubmed

Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.

HSPA1A HSPA1B

6.92e-06292216482515
Pubmed

Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.

HSPA1A HSPA1B

6.92e-06292211864979
Pubmed

Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.

HSPA1A HSPA1B

6.92e-06292215719414
Pubmed

Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.

HSPA1A HSPA1B

6.92e-06292226976620
Pubmed

Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.

HSPA1A HSPA1B

6.92e-06292221187371
Pubmed

Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.

HSPA1A HSPA1B

6.92e-06292220430459
Pubmed

Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.

HSPA1A HSPA1B

6.92e-06292220235222
Pubmed

Genetic determinants of HSP70 gene expression following heat shock.

HSPA1A HSPA1B

6.92e-06292220876613
Pubmed

The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.

HSPA1A HSPA1B

6.92e-06292220223214
Pubmed

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.

HSPA1A HSPA1B

6.92e-06292220093776
Pubmed

Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.

HSPA1A HSPA1B

6.92e-06292223704948
InteractionCCDC117 interactions

HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

1.03e-0726915int:CCDC117
InteractionBGLT3 interactions

CKB GANAB ALDH18A1 PRKDC HSPA8 HSP90AB1

1.12e-0675916int:BGLT3
InteractionISG15 interactions

FLNB IBTK UBA7 GANAB CAPN7 RNF213 PRKDC HSPA1A HSPA1B HSPA8 HSP90AB1 KLHL26

2.24e-064949112int:ISG15
InteractionFYN interactions

IVNS1ABP PRUNE2 PMS2 SRSF10 CAPN7 SH3KBP1 PRKCH HSPA1A HSPA8 HSP90AB1 HSP90AB3P

3.84e-064319111int:FYN
InteractionRAD21 interactions

FLNB NAA15 HECW2 CHTF18 CST9L PRKDC HSPA1A STAG2 HSPA8 HSP90AB1

9.15e-063849110int:RAD21
InteractionPRKCE interactions

STK32A IBTK PRKCH HSPA1A HSPA8 HSP90AB1 HSP90AB3P

1.34e-05173917int:PRKCE
InteractionHYPK interactions

MYH11 NAA15 HSPA1A HSPA8 NAA16 HSP90AB1

2.19e-05125916int:HYPK
InteractionLRRC28 interactions

NFATC1 HSPA1B HSPA8

2.47e-0513913int:LRRC28
InteractionPIAS1 interactions

FLNB SETDB1 SRSF10 STAB2 GANAB NFATC1 ALDH18A1 HSPA1A HSPA8

3.11e-05353919int:PIAS1
InteractionRBX1 interactions

CKB FLNB IBTK COPS9 SRSF10 MYH11 GANAB PRKDC HSPA1A HSPA8 HSP90AB1

4.24e-055589111int:RBX1
InteractionFGD5 interactions

FLNB KRT7 MYH11 HSPA1A UTRN HSPA8 HSP90AB1

4.25e-05207917int:FGD5
InteractionTCERG1 interactions

SETDB1 SRSF10 CPSF6 ICE1 HSPA1A HSPA1B HSPA8

4.25e-05207917int:TCERG1
InteractionHSP90AA1 interactions

STK32A SMG1 SETDB1 SRSF10 CHTF18 STK32B NFRKB NBN PRKCH PRKDC STK32C HSPA1A HSPA1B HSPA8 HSP90AB1 KLHL26 HSP90AB3P

4.41e-0512639117int:HSP90AA1
InteractionPTPN12 interactions

FLNB GANAB PRKDC HSPA1A UTRN HSPA8

5.04e-05145916int:PTPN12
InteractionMYLK4 interactions

GANAB CPSF6 ALDH18A1 HSP90AB1 HSP90AB3P

5.46e-0590915int:MYLK4
InteractionTSSK6 interactions

HSPA1A HSPA8 HSP90AB1 HSP90AB3P

5.98e-0547914int:TSSK6
InteractionCHMP4C interactions

FLNB SRSF10 MYH11 GANAB CPSF6 SH3KBP1 ALDH18A1 HS3ST5 RNF213 PRKDC HSP90AB1 HSP90AB3P

6.01e-056879112int:CHMP4C
InteractionACIN1 interactions

KLHL2 CPSF6 PRKDC SNRPB2 HSPA1A HSPA8 HSP90AB1 KLHL26

6.55e-05301918int:ACIN1
InteractionSPEF2 interactions

CKB SPEF2 HSP90AB1

6.92e-0518913int:SPEF2
InteractionSIX1 interactions

EYA1 EYA2 EYA3 HSP90AB1

7.06e-0549914int:SIX1
InteractionKCTD9 interactions

CKB FLNB PRKDC HSPA1B HSPA8 HSP90AB1 KLHL26

7.20e-05225917int:KCTD9
InteractionTRAF3IP1 interactions

CKB HSPA1A HSPA8 NME8 HSP90AB1

7.43e-0596915int:TRAF3IP1
InteractionANKRD55 interactions

CKB GANAB ALDH18A1 PRKDC HSPA1A HSPA8 HSP90AB1

7.82e-05228917int:ANKRD55
InteractionRPS6KA4 interactions

HECW2 SH3KBP1 LAMP3 HSP90AB1 HSP90AB3P

9.02e-05100915int:RPS6KA4
InteractionMYLK2 interactions

FLNB HSPA1A HSPA8 HSP90AB1 HSP90AB3P

9.46e-05101915int:MYLK2
InteractionFBXL4 interactions

HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

1.19e-04106915int:FBXL4
InteractionPHLPP1 interactions

FLNB KRT7 CPSF6 U2AF1L4 PRKDC DIAPH3 HSPA1A HSPA8

1.32e-04333918int:PHLPP1
InteractionKCNA3 interactions

CKB FLNB GANAB SPEF2 ALDH18A1 RNF213 RP1 PRKDC DIAPH3 SMCR8 HSPA1B HSPA8 HSP90AB1

1.42e-048719113int:KCNA3
InteractionTUBGCP2 interactions

SRSF10 HECW2 SH3KBP1 HSPA1A HSPA8 HSP90AB1

1.47e-04176916int:TUBGCP2
InteractionMAP1B interactions

CKB CACNA1A SETDB1 APEH PRKDC HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

1.59e-045399110int:MAP1B
InteractionUBE3A interactions

CKB KRT7 ALDH1A2 SACS HSPA1A UTRN HSPA8 TAT HSP90AB1

1.70e-04441919int:UBE3A
InteractionC3orf18 interactions

SMG1 SACS PRKDC DIAPH3 STAG2

1.74e-04115915int:C3orf18
InteractionSRRM1 interactions

CPSF6 SH3KBP1 AKAP13 PRKDC SNRPB2 HSPA1A STAG2 HSPA8

1.78e-04348918int:SRRM1
InteractionHSPH1 interactions

FLNB GANAB HECW2 SH3KBP1 HSPA1A HSPA1B UTRN HSPA8 HSP90AB1

1.91e-04448919int:HSPH1
InteractionOBSL1 interactions

CKB PRUNE2 KLHL2 FLNB SRSF10 GANAB NFATC1 CPSF6 PRKDC SNRPB2 UTRN STAG2 HSP90AB1

2.00e-049029113int:OBSL1
InteractionCDK2 interactions

CKB FLNB GANAB ALDH18A1 NBN PRKCH PRKDC HSPA1A HSPA8 TFDP1 TFDP2 HSP90AB1

2.05e-047839112int:CDK2
InteractionAGRN interactions

CKB CACNA1A FLNB MYH11 NAA15 HSPA8 HSP90AB1

2.08e-04267917int:AGRN
InteractionMETTL14 interactions

CKB KRT7 SRSF10 GANAB CPSF6 PRKDC SNRPB2 HSPA1A HSPA8 HSP90AB1

2.10e-045589110int:METTL14
InteractionTOLLIP interactions

IVNS1ABP SETDB1 CPSF6 APEH PRKDC DIAPH3 HSPA1B HSPA8

2.16e-04358918int:TOLLIP
InteractionPRKCG interactions

IVNS1ABP IBTK HSPA1A HSPA8 HSP90AB1

2.21e-04121915int:PRKCG
InteractionMSH6 interactions

IVNS1ABP PMS2 GANAB NBN PRKDC HSPA1A HSPA8

2.28e-04271917int:MSH6
InteractionSRSF10 interactions

SRSF10 CPSF6 HECW2 SH3KBP1 PRKDC HSPA1A HSP90AB1

2.28e-04271917int:SRSF10
InteractionROCK1 interactions

NAA15 RHOD LAMP3 PRKDC HSPA1A HSPA8

2.36e-04192916int:ROCK1
InteractionHCK interactions

IVNS1ABP SH3KBP1 HSPA1A HSPA8 HSP90AB1 HSP90AB3P

2.42e-04193916int:HCK
InteractionNME1 interactions

EYA2 EYA3 HSPA1A HSPA8 HSP90AB1 HSP90AB3P

2.42e-04193916int:NME1
InteractionGPRC5A interactions

RHOD LAMP3 HSPA1A HSPA8

2.54e-0468914int:GPRC5A
InteractionST13 interactions

CPSF6 HSPA1A HSPA1B UTRN HSPA8 HSP90AB1

2.56e-04195916int:ST13
InteractionAXL interactions

GANAB PRKDC HSPA1A HSPA1B UTRN HSPA8 HSP90AB1 HSP90AB3P

2.65e-04369918int:AXL
InteractionMAP2K2 interactions

CKB RHOD HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

2.66e-04278917int:MAP2K2
InteractionATP1A1 interactions

FLNB SLC8A1 NAA15 RHOD LAMP3 RNF213 PRKDC STK32C HSPA1A HSPA8

2.67e-045759110int:ATP1A1
InteractionCRK interactions

IVNS1ABP CHTF18 SH3KBP1 EYA3 HSPA1A HSPA1B HSPA8 HSP90AB1

2.70e-04370918int:CRK
InteractionPCDH7 interactions

CKB GANAB RHOD LAMP3 HSPA1A HSPA8 HSP90AB1

2.72e-04279917int:PCDH7
InteractionYES1 interactions

PRUNE2 RHOD CPSF6 LAMP3 HSPA1A HSPA8 HSP90AB1 HSP90AB3P

2.96e-04375918int:YES1
InteractionSIX2 interactions

EYA1 EYA2 EYA3

2.99e-0429913int:SIX2
InteractionSIX5 interactions

DIAPH3 EYA1 EYA3

2.99e-0429913int:SIX5
InteractionFBXL15 interactions

HECW2 HSPA1B HSPA8

2.99e-0429913int:FBXL15
InteractionRUFY1 interactions

RHOD ALDH18A1 RNF213 PRKDC HSPA1A HSPA1B HSPA8 HSP90AB1 HSP90AB3P

2.99e-04476919int:RUFY1
InteractionANK3 interactions

IVNS1ABP FLNB RHOD VPS33B UTRN HSP90AB1

3.01e-04201916int:ANK3
InteractionPOU5F1 interactions

FLNB SETDB1 IBTK GANAB CPSF6 NFRKB NBN PRKDC SNRPB2 HSPA8

3.02e-045849110int:POU5F1
InteractionRNF123 interactions

IVNS1ABP FLNB HECW2 ALDH18A1 RNF213 AKAP13 ICE1 PRKDC CSMD2 UTRN HSPA8 HSP90AB1

3.27e-048249112int:RNF123
InteractionHLA-DRB5 interactions

STAG2 HSPA8 HSP90AB1

3.31e-0430913int:HLA-DRB5
InteractionSTK35 interactions

HSPA8 HSP90AB1 HSP90AB3P

3.31e-0430913int:STK35
InteractionSUMO2 interactions

CKB FLNB SETDB1 RNF213 NBN PRKDC HSPA1A STAG2 HSPA8 HSP90AB1

3.32e-045919110int:SUMO2
InteractionLRRC31 interactions

FLNB KRT7 MYH11 AKAP13 ICE1 PRKDC

3.35e-04205916int:LRRC31
InteractionARHGAP24 interactions

CKB GANAB NAA15 CPSF6 ALDH18A1 HSPA1A HSPA1B HSPA8 HSP90AB1

3.49e-04486919int:ARHGAP24
InteractionCWC15 interactions

CPSF6 PRKDC SNRPB2 HSPA1A HSPA8

3.55e-04134915int:CWC15
InteractionARFIP1 interactions

FLNB LAMP3 HSPA1A HSPA8 TFDP2

3.55e-04134915int:ARFIP1
InteractionANKK1 interactions

HSPA1A STAG2 HSP90AB1

3.65e-0431913int:ANKK1
InteractionMAU2 interactions

NFATC1 PRKDC STAG2 HSPA8 HSP90AB1

3.80e-04136915int:MAU2
InteractionGRPEL1 interactions

SH3KBP1 ALDH18A1 EYA1 EYA3 HSPA1A HSPA8

3.81e-04210916int:GRPEL1
InteractionUBE2L3 interactions

CACNA1A RNF220 UBA7 HECW2 RNF213 HSPA8

3.90e-04211916int:UBE2L3
InteractionCCDC28A interactions

RHOD EYA2 EYA3

4.02e-0432913int:CCDC28A
InteractionMCIDAS interactions

TFDP1 TFDP2

4.17e-047912int:MCIDAS
InteractionRP1L1 interactions

RP1 HSPA1A

4.17e-047912int:RP1L1
InteractionRNF207 interactions

HSPA1A HSPA8

4.17e-047912int:RNF207
InteractionCHMP4B interactions

FLNB SRSF10 MYH11 CAPN7 SH3KBP1 ALDH18A1 PRKDC HSPA1A HSPA8 HSP90AB1 HSP90AB3P

4.28e-047279111int:CHMP4B
InteractionSWAP70 interactions

GANAB HSPA1A HSPA8 HSP90AB1

4.30e-0478914int:SWAP70
InteractionCDCA5 interactions

PRKDC HSPA1A STAG2 HSPA8 NAA16

4.34e-04140915int:CDCA5
InteractionNAA40 interactions

CKB IBTK ALDH1A2 NAA15 CPSF6 NBN ICE1 PRKDC SMCR8 HSPA1A UTRN HSPA8 HSP90AB1

4.36e-049789113int:NAA40
InteractionZRANB3 interactions

COPS9 HECW2 LAMP3

4.41e-0433913int:ZRANB3
InteractionPNPLA5 interactions

HSPA1B HSPA8 HSP90AB1

4.41e-0433913int:PNPLA5
InteractionGNB2 interactions

CACNA1A CHTF18 ALDH18A1 RNF213 EYA2 HSPA1A HSPA1B HSPA8 HSP90AB1

4.41e-04502919int:GNB2
InteractionWDFY4 interactions

MYH11 GANAB CPSF6 HSPA8 HSP90AB1

4.48e-04141915int:WDFY4
InteractionATOH1 interactions

SACS RNF213 PRKDC UTRN

4.73e-0480914int:ATOH1
InteractionSYNE2 interactions

IVNS1ABP RHOD VPS33B LAMP3 PRKDC HSPA8

4.75e-04219916int:SYNE2
InteractionRNF31 interactions

IVNS1ABP SRSF10 CPSF6 CAPN7 HSPA1A HSPA1B HSPA8 HSP90AB1

4.77e-04403918int:RNF31
InteractionMAPK7 interactions

IVNS1ABP GANAB HSPA1A HSPA8 HSP90AB1

4.78e-04143915int:MAPK7
InteractionCSK interactions

IVNS1ABP AFMID IBTK SLC8A1 VPS33B HECW2 FSD2 XYLB HSPA1A HSPA8 NME8 HSP90AB1

4.85e-048619112int:CSK
InteractionPFN1 interactions

CKB CPSF6 U2AF1L4 NBN AKAP13 DIAPH3 EYA1 HSPA8 HSP90AB1

4.87e-04509919int:PFN1
InteractionSMC3 interactions

IVNS1ABP MYH11 NFATC1 CST9L PRKDC HSPA1A STAG2 HSPA8

5.18e-04408918int:SMC3
InteractionPRKCA interactions

IVNS1ABP IBTK NFATC1 AKAP13 PRKCH HSPA1A HSPA8 TFDP2

5.18e-04408918int:PRKCA
InteractionGSK3B interactions

IBTK RNF220 GANAB NFATC1 HECW2 APEH PRKDC EYA1 HSPA1A UTRN HSPA8 HSP90AB1

5.21e-048689112int:GSK3B
InteractionUSP50 interactions

HSPA1A HSPA8 HSP90AB1

5.25e-0435913int:USP50
InteractionTRIM37 interactions

AFMID FLNB KRT7 CPSF6 NFRKB PRKDC DIAPH3 HSPA1B HSPA8 HSP90AB1

5.48e-046309110int:TRIM37
InteractionSPDL1 interactions

FLNB MYH11 PRKDC HSPA1A STAG2 HSPA8 HSP90AB1

5.62e-04315917int:SPDL1
InteractionSTIP1 interactions

FLNB SRSF10 NAA15 PRKDC STK32C EYA3 HSPA1A HSPA1B STAG2 HSPA8 TFDP2 HSP90AB1 HSP90AB3P

5.69e-0410069113int:STIP1
InteractionFAM83F interactions

HSPA1A HSPA1B HSPA8

5.71e-0436913int:FAM83F
InteractionMETTL21A interactions

HSPA1A HSPA1B HSPA8

5.71e-0436913int:METTL21A
InteractionKBTBD4 interactions

SMG1 NAA15 NFRKB PRKDC HSPA1A HSPA1B HSPA8

5.73e-04316917int:KBTBD4
InteractionPPP6C interactions

GANAB PRKDC HSPA1A UTRN HSPA8 HSP90AB1

5.88e-04228916int:PPP6C
GeneFamilyEYA transcriptional coactivator and phosphatases

EYA1 EYA2 EYA3

2.03e-0746831044
GeneFamilyKelch like|BTB domain containing

IVNS1ABP KLHL2 KLHL33 KLHL26

1.84e-0542684617
GeneFamilyHeat shock 70kDa proteins

HSPA1A HSPA1B HSPA8

3.33e-0517683583
GeneFamilyTranscription factor Dp family

TFDP1 TFDP2

4.17e-053682987
GeneFamilyN(alpha)-acetyltransferase subunits|GCN5 related N-acetyltransferases

NAA15 NAA16

8.98e-0412682660
GeneFamilyBasic leucine zipper proteins|BTB domain containing

IVNS1ABP KLHL2 IBTK KLHL26

1.63e-03134684861
GeneFamilyAldehyde dehydrogenases

ALDH1A2 ALDH18A1

2.29e-0319682398
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA6C SEMA3C

2.53e-0320682736
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA2D4

4.27e-0326682253
CoexpressionNAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_DN

FLNB TMPRSS15 NFATC1 STK32B NBN AKAP13 PLEK KLHL26

3.82e-06260928M41075
CoexpressionKRISHNAN_FURIN_TARGETS_UP

HSPA1A HSPA1B HSPA8

4.93e-0610923MM1243
CoexpressionLAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES

SLC8A1 MYH11 AKAP13 HSPA1A HSPA1B UTRN

1.82e-05155926M39246
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

KRT7 SH3KBP1 RNF213 HSPA1A HSPA1B UTRN HSP90AB1

1.90e-07199927155b03b859157013e9142e9248551369127d9204
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

LAMP3 RNF213 HSPA1A HSPA1B HSPA8 HSP90AB1

1.83e-06177926a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

LAMP3 RNF213 HSPA1A HSPA1B HSPA8 HSP90AB1

1.90e-06178926ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

CACNA1A PRUNE2 FLNB SLC8A1 MYH11 HMCN2

2.23e-06183926818fd886e0188091310825f9145fa53328f2c979
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IVNS1ABP RNF213 PRKCH PLEK UTRN TFDP2

2.52e-061879260bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 ALDH1A2 STK32B DIAPH3 EYA1 UTRN

2.60e-0618892663a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CKB PRUNE2 SEMA3C SLC8A1 MYH11 EYA2

2.76e-06190926938d1f66094b1c94606e0d40213a39e5112f3322
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKB IVNS1ABP KRT7 ALDH1A2 HSP90AB1 ZNF44

2.76e-06190926498bbe063bc75d323cb186a82cce122b511d2cff
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 SPEF2 RNF213 PRKCH UTRN IMPG2

3.40e-06197926e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CKB PRUNE2 SEMA3C MYH11 APOBEC2 HSPA1A

3.40e-061979264797f414330316e2ac2cf7cd2570d991877d7a38
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CKB PRUNE2 SEMA3C SLC8A1 MYH11 HSP90AB1

3.71e-06200926dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

CACNA1A PRUNE2 MYH11 HMCN2 UTRN

2.11e-0516192547b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HMCN2 APEH HSPA1A HSPA1B HSPA8

2.37e-051659253c8baed838eccb6e720bacb7458f087647dc1222
ToppCell15-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

CKB PRUNE2 SEMA3C SLC8A1 MYH11

2.37e-05165925531804467601e1ee1f771cffa21501f6d464ae10
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

B3GALT1 STK32A KLHL2 PLA2R1 HECW2

2.51e-05167925e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCellControl-CD4+_T_activated|World / Disease group and Cell class

ALDH1A2 NFATC1 HECW2 HSPA1A HSPA1B

2.98e-0517392512f8e4276b290bb388a56de4c8d8dd60415b2f63
ToppCellControl-CD4+_T_activated|Control / Disease group and Cell class

ALDH1A2 NFATC1 HECW2 HSPA1A HSPA1B

3.06e-051749252b683e81b315ad22555314433aed5681feb48da8
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKB B3GALT1 MYH11 CHTF18 DIAPH3

3.06e-051749257b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 ALDH1A2 DIAPH3 EYA1 UTRN

3.23e-05176925327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IVNS1ABP STK32A SLC8A1 PCDHB13 CHRFAM7A

3.32e-05177925c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA6C FLNB SEMA3C SACS STK32B

3.60e-05180925c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32A MYH11 SACS HECW2 IMPG2

3.60e-0518092579c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB2 HECW2 STK32B HSPA1A UTRN

3.69e-05181925e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLNB KRT7 RP1 EYA1 EYA2

3.79e-05182925215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STK32A PRUNE2 FLNB HSPA1A UTRN

3.79e-05182925c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STK32A PRUNE2 FLNB HSPA1A UTRN

3.79e-05182925d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB KRT7 SLC8A1 HSBP1L1 STK32B

3.89e-05183925f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNA1A PRUNE2 FLNB MYH11 HMCN2

3.89e-05183925cae2ee08f985a6f005b4b8e959e465350315156a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STK32A PRUNE2 FLNB HSPA1A UTRN

3.99e-05184925087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CKB PRUNE2 FLNB SLC8A1 MYH11

3.99e-0518492539168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB KRT7 SLC8A1 HSBP1L1 STK32B

3.99e-051849258939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCellnormal-na-Lymphocytic_NK-NK_dim-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 PRKCH PLEK UTRN TFDP2

4.10e-05185925b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SLC8A1 AKAP13 HSPA1A HSPA1B UTRN

4.31e-051879250099def970fbc828756fbf853eca2ce77b8cd342
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

PRUNE2 FLNB SLC8A1 MYH11 HMCN2

4.42e-0518892534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

CKB KRT7 HSBP1L1 NFRKB KLHL26

4.42e-05188925c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

CKB KRT7 HSBP1L1 NFRKB KLHL26

4.42e-051889259155b9a92496e75646778c025b02947e9e9ec73a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CKB PRUNE2 SEMA3C MYH11 EYA2

4.42e-05188925f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellControl-B_intermediate-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IVNS1ABP FLNB SACS RNF213 PLEK

4.54e-0518992511cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

STK32A PLA2R1 KRT7 HS3ST5 DIAPH3

4.54e-051899255a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CKB KRT7 SEMA3C SLC8A1 HSPA1A

4.65e-05190925223587b5df037794a2cee234babf87d12bf48ac8
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CKB STK32B EYA1 HSPA1A HSPA8

4.65e-051909254a777d8aa19cadd3b61b023772df142421a89113
ToppCellCOVID-19-kidney-Stressed_EC|kidney / Disease (COVID-19 only), tissue and cell type

HECW2 PRKCH HSPA1A HSPA1B HSP90AB1

4.77e-05191925d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CKB PRUNE2 SEMA3C SLC8A1 MYH11

4.89e-05192925992d08092edbc68c47b945deb8708379738c239a
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

GANAB PRKDC SMCR8 UTRN STAG2

5.01e-05193925abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IVNS1ABP KRT7 ALDH1A2 RP1 DIAPH3

5.01e-05193925263d185af6ed80e639f864e4966268e0862c61dc
ToppCellILEUM-inflamed-(2)_B_cell-(2)_Memory_B_cells|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PLEK HSPA1A HSPA1B HSPA8 HSP90AB1

5.01e-05193925a2ca508b1a6184579083f59419f4701c28d379ab
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IVNS1ABP KRT7 ALDH1A2 RP1 DIAPH3

5.01e-0519392580e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IVNS1ABP KRT7 ALDH1A2 RP1 DIAPH3

5.01e-05193925b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellT_cells-CD56_dim_CD16+_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

IVNS1ABP PRKCH PLEK NME8 TFDP2

5.14e-05194925335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 PRKCH PLEK UTRN TFDP2

5.26e-05195925609732e83ab7fc3ba7dace66f5a17e46557fd6d1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHTF18 XYLB PRKDC DIAPH3 TFDP1

5.26e-05195925cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CHTF18 XYLB PRKDC DIAPH3 TFDP1

5.39e-05196925df366d76ea55f49e349d622effa57c1535df8400
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 SEMA3C SLC8A1 MYH11 SACS

5.39e-051969259830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 NFATC1 HECW2 PRKCH UTRN

5.39e-05196925629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 SLC8A1 MYH11 HMCN2 SACS

5.52e-05197925bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellmyeloid-Monocyte-CD16+_Monocyte|myeloid / Lineage, cell class and subclass

CKB AFMID UTRN HSPA8 HSP90AB1

5.52e-051979257ed5dc82ead20406586252ef07164afad8a49994
ToppCell5'-GW_trimst-1.5-LargeIntestine|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB MYH11 HSPA1A HSPA8 HSP90AB1

5.52e-051979250b2ad6a933ff1a325649cc8f139380fd158a1d42
ToppCellCOVID-19_Severe-NK_activated|World / disease group, cell group and cell class

RNF213 PRKCH PLEK UTRN TFDP2

5.52e-05197925a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

RNF213 PRKCH PLEK UTRN TFDP2

5.66e-05198925d7053a898e04478c577381085f615edaad3cdc5b
ToppCellmyeloid-Monocyte-CD16+_Monocyte|Monocyte / Lineage, cell class and subclass

CKB AFMID UTRN HSPA8 HSP90AB1

5.66e-05198925a41fa60098e59add84a1687a303c710ab1baa137
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB HS3ST5 RP1 EYA1 EYA2

5.66e-05198925af399569c718f5fd971d73a7926768c9311002a3
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 PRKCH PLEK UTRN TFDP2

5.66e-051989250e918e9db9b884f5328d438e90efe065e27266ee
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

SMG1 RNF213 AKAP13 PLEK UTRN

5.66e-0519892561ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRKCH PLEK HSPA1A HSPA1B HSPA8

5.66e-05198925294a48ef6c0b89c7be948452cea79d23d3901e75
ToppCellmLN-B_cell-B_cell_memory|B_cell / Region, Cell class and subclass

SH3KBP1 HSPA1A HSPA1B HSPA8 HSP90AB1

5.66e-05198925e2c63ca9f82f8524447e398b11a676b22d2f58ce
ToppCellremission-NK|World / disease stage, cell group and cell class

RNF213 AKAP13 PRKCH PLEK TFDP2

5.66e-05198925383ed78164ad37826100d3de6c3cc14f62e01813
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PRKCH HSPA1A HSPA1B HSPA8 HSP90AB1

5.66e-05198925ec115c4a5dbc54206c72140aa0c8d6a7c29c5563
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 PRKCH PLEK UTRN TFDP2

5.66e-05198925ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB HS3ST5 RP1 EYA1 EYA2

5.66e-051989251408e02e053ad3406229bfe8189da03be6366e81
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNF213 PRKCH PLEK UTRN TFDP2

5.66e-05198925fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

RNF213 PRKCH PLEK UTRN TFDP2

5.66e-05198925aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF213 PRKCH PLEK UTRN TFDP2

5.66e-051989251ef3a6bd681c223eed58300348adfef89df5563c
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

IVNS1ABP HSPA1A HSPA1B HSPA8 HSP90AB1

5.66e-05198925a1c8e5c332336823c47c04e56b6d7bc8f057c9da
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 SRSF10 RNF213 PRKCH UTRN

5.79e-05199925f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK_activated|COVID-19_Severe / Disease group, lineage and cell class

RNF213 PRKCH PLEK UTRN TFDP2

5.79e-05199925edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IVNS1ABP RNF213 PRKCH UTRN TFDP2

5.79e-05199925df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

RNF213 PRKCH PLEK UTRN TFDP2

5.79e-05199925e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CKB PRUNE2 SEMA3C MYH11 HSP90AB1

5.79e-05199925e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellremission-NK|remission / disease stage, cell group and cell class

RNF213 AKAP13 PRKCH PLEK TFDP2

5.79e-0519992531ed2a314e8f70980ea0686242446d66929288e9
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IVNS1ABP RNF213 PRKCH UTRN TFDP2

5.79e-05199925ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 PRKCH PLEK UTRN TFDP2

5.79e-051999254820f5bcd7bc34c2ebf6a3422cc8eb383a3b5a4e
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 PRKCH PLEK UTRN TFDP2

5.79e-05199925eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNF213 PRKCH PLEK UTRN TFDP2

5.79e-0519992510c8729b779073c3bf808e85958d59147f0be5c5
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRKCH PLEK HSPA1A HSPA1B HSPA8

5.79e-0519992554b64f01e7a73a88bd92b6d4e73cccde60396b2d
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 PRKCH PLEK UTRN TFDP2

5.79e-05199925867fd292f3879982422e840e087bfdb3b21a8715
ToppCellControl-Lymphoid_T/NK-NK|Control / Disease group, lineage and cell class

RNF213 PRKCH PLEK UTRN TFDP2

5.79e-0519992594b2693a8378b9b2c58c6aebb2c6658d75b2e3de
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

RNF213 PRKCH PLEK UTRN TFDP2

5.79e-051999255f914962e2572b0c6372465b81b7496fa663d93c
ToppCellH1299-uninfected|H1299 / Cell line, Condition and Strain

CKB HSPA1A HSPA1B HSPA8 HSP90AB1

5.79e-051999254594eb3e6d29285155df8dfd322ccf532d7e94b8
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB SPEF2 RNF213 PRKCH UTRN

5.93e-05200925dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellremission-CD8+_Tem|World / disease stage, cell group and cell class

RNF213 AKAP13 PRKCH PLEK HSPA8

5.93e-052009250ebf0dda91fc7adb9ea69734ad9dcc65d0082c6d
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

STK32A CACNA1A SLC8A1 STK32B CSMD2

5.93e-05200925f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

STK32A CACNA1A SLC8A1 STK32B CSMD2

5.93e-05200925cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellproximal-mesenchymal-Fibromyocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CKB PRUNE2 SEMA3C MYH11 HMCN2

5.93e-0520092537d9f46f727a31e8e94e348e4ddd71a2125ba01a
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLA2R1 ALDH1A2 ALDH18A1 EYA1 EYA2

5.93e-05200925030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 SLC8A1 MYH11 HMCN2 SACS

5.93e-05200925a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellproximal-3-mesenchymal-Fibromyocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CKB PRUNE2 SEMA3C MYH11 HMCN2

5.93e-05200925ed6fbe61a04d29b105054f7058abe7469314b304
ToppCellControl-Control-Lymphocyte-T/NK-NK|Control / Disease, condition lineage and cell class

RNF213 PRKCH PLEK UTRN TFDP2

5.93e-05200925c64c27dbf4df42ca2ad2bd94b50fab87b4050ef3
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

STK32A CACNA1A SLC8A1 STK32B CSMD2

5.93e-05200925c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 SRSF10 RNF213 AKAP13 UTRN

5.93e-0520092512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CKB PRUNE2 SEMA3C MYH11 HSP90AB1

5.93e-05200925c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HSPA1A HSPA1B HSPA8 HSP90AB1

1.27e-0450564GAVISH_3CA_METAPROGRAM_B_CELLS_HSP_STRESS
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HSPA1A HSPA1B HSPA8 HSP90AB1

1.27e-0450564GAVISH_3CA_METAPROGRAM_MACROPHAGES_STRESS_HSP
Diseasegraft-versus-host disease (biomarker_via_orthology)

HSPA1A HSPA1B HSPA8

2.64e-075893DOID:0081267 (biomarker_via_orthology)
Diseaseeye disease (implicated_via_orthology)

EYA1 EYA2 EYA3

5.27e-076893DOID:5614 (implicated_via_orthology)
Diseasebranchiootorenal syndrome (implicated_via_orthology)

EYA1 EYA2 EYA3

9.20e-077893DOID:14702 (implicated_via_orthology)
DiseaseProstatic Neoplasms

IVNS1ABP SETDB1 ALDH1A2 STAB2 NBN AKAP13 PRKDC HSPA1A HSP90AB1

1.02e-04616899C0033578
DiseaseMalignant neoplasm of prostate

IVNS1ABP SETDB1 ALDH1A2 STAB2 NBN AKAP13 PRKDC HSPA1A HSP90AB1

1.02e-04616899C0376358
Diseaseposterior thigh muscle fat infiltration measurement

HMCN2 EYA1 EYA2

1.62e-0435893EFO_0020934
DiseaseMajor depression, single episode

HSPA1A HSPA1B

3.19e-049892C0024517
Diseaseaspartate aminotransferase measurement

CKB FLNB SETDB1 ALDH1A2 HMCN2 HSBP1L1 RNF213 AKAP13 EYA1 EYA2

3.96e-049048910EFO_0004736
Diseaseresponse to carboplatin, response to antineoplastic agent

FLNB SPEF2

3.98e-0410892GO_0097327, GO_0097328
Diseasemismatch repair cancer syndrome (is_implicated_in)

PMS2 TFDP1

5.82e-0412892DOID:0112182 (is_implicated_in)
DiseaseMetastatic melanoma

STK32A STK32B PRKDC

5.89e-0454893C0278883
Diseasesalicylurate measurement

B3GALT1 CHTF18

6.87e-0413892EFO_0010532
Diseaseobsolete_red blood cell distribution width

SEMA3C SRSF10 VPS33B HECW2 NFRKB APEH AKAP13 RP1 PLEK SMCR8 HSPA8 HSP90AB1

7.18e-0413478912EFO_0005192
DiseaseRhabdomyosarcoma

PMS2 NBN

9.21e-0415892C0035412
Diseasemelanoma

SETDB1 PCDHB8 HS3ST5 HSPA1A STAG2

9.42e-04248895C0025202
DiseaseBMI-adjusted waist-hip ratio, physical activity measurement

GANAB EYA1 EYA2

1.20e-0369893EFO_0007788, EFO_0008002
Diseasedisease free survival

ICE1 CDH8

1.33e-0318892EFO_0000409
Diseasetemporal horn of lateral ventricle volume measurement

STK32A DIAPH3 UTRN

1.36e-0372893EFO_0010333
Diseaseabnormal paneth cell measurement

SPEF2 EYA1

1.49e-0319892EFO_0007963
Diseasecitrulline measurement

HMCN2 ALDH18A1

1.65e-0320892EFO_0009777
Diseaselongevity

SEMA6C B3GALT1 VPS33B RP1 EYA1

1.71e-03284895EFO_0004300
DiseaseGlioma

PMS2 NBN STAG2

2.34e-0387893C0017638
DiseaseCarcinoma, Pancreatic Ductal

HSPA1A HSPA1B

2.38e-0324892C0887833
Diseasecomplement C4b measurement

HSPA1A HSPA1B

2.58e-0325892EFO_0008092
DiseaseIschemic stroke, coronary artery disease

SEMA3C RNF213 RP1

2.74e-0392893EFO_0001645, HP_0002140
Diseasemacular degeneration (is_marker_for)

SRSF10 HSPA8

2.79e-0326892DOID:4448 (is_marker_for)
Diseasemultisite chronic pain

UBA7 VPS33B UTRN

3.01e-0395893EFO_0010100

Protein segments in the cluster

PeptideGeneStartEntry
DEDEFQITEHNNFRT

CACNA1A

1726

O00555
VEDDFHNQFAAELEV

CHTF18

11

Q8WVB6
IHLAFNDIDVEPQFD

CSMD2

616

Q7Z408
EKAVHADFFNDFEDL

COPS9

36

Q8WXC6
FADADLDYAVEQAHQ

ALDH1A2

296

O94788
EQESQIFHDIIVEDF

B3GALT1

131

Q9Y5Z6
VFVVAEEDFHFVQDE

AKAP13

81

Q12802
HFSFQEEEQIDFQEG

ASMT

221

P46597
FEKEFTDHQETQAEL

DIAPH3

516

Q9NSV4
EDEHAAAHAEEAFFN

APOBEC2

91

Q9Y235
EEVSEALHDVDFQQL

CCDC113

211

Q9H0I3
FFNDLEECDQVHVED

EYA3

356

Q99504
FEELHDVDHFEIVEN

AFMID

271

Q63HM1
LHIDSDEEDHEFQQD

HECW2

461

Q9P2P5
EFFQAELQVIDINDH

PCDHB13

116

Q9Y5F0
KEAFEVFDHESNNTV

EFCAB2

156

Q5VUJ9
HHGEEEVETFAFQAE

HSP90AB1

6

P08238
DELHVQEEFEAFVAA

KLHL33

126

A6NCF5
EHFPEFENDVEFTER

TAT

381

P17735
EEEFERIHQAQAAAA

NFRKB

656

Q6P4R8
AEVFGSDDDHIQFVQ

IVNS1ABP

241

Q9Y6Y0
EAEQQQLIDDHFLFD

CKB

181

P12277
EDEINHRTAAENEFV

KRT7

181

P08729
VNFHEDDNQKSAFEV

IBTK

671

Q9P2D0
HHGEEEVETFAFQAE

HSP90AB3P

6

Q58FF7
DADLQVQDFEEHYVQ

HMCN2

4521

Q8NDA2
LHFQEFDLENINDVV

TMPRSS15

566

P98073
DEEDVDFDIIHNAND

FLNB

791

O75369
VVKASQEIHFFDNDE

HS3ST5

116

Q8IZT8
EDFDNRLVNHFVEEF

HSPA1B

231

P0DMV9
VERHFFEITDDQFDF

NAA16

511

Q6N069
DTHLFFNDLEECDQV

EYA1

371

Q99502
NNNQFFHDVEVEDVL

NFATC1

131

O95644
TDVQLQAFDFEDDHF

LAMP3

356

Q9UQV4
DIADERFDATFHTNV

CHRFAM7A

26

Q494W8
IERHFIEITDDQFDF

NAA15

511

Q9BXJ9
TEDENTAEFFLQHVD

ALDH18A1

701

P54886
HDNVHAVFQEAAEVA

RHOD

176

O00212
DHDHFFDEDLQAAID

ICE1

321

Q9Y2F5
AFTFRHFLQIAEEED

KLHL26

186

Q53HC5
DHIDIYADVGEEFNQ

CPSF6

6

Q16630
HFLVTQAFDEDEKEN

CAPN7

91

Q9Y6W3
EAAEEADLNHEFNES

CACNA2D4

146

Q7Z3S7
EDFDNRLVNHFVEEF

HSPA1A

231

P0DMV8
VDEFINVRLHEADND

CDH8

721

P55286
FEDDIDNCHFQESTE

CST9L

101

Q9H4G1
RHDIAFVEFENDGQA

SNRPB2

186

P08579
HENDNAFLANEEKAI

SACS

4021

Q9NZJ4
EDFDNRMVNHFIAEF

HSPA8

231

P11142
EFFQAELQVIDINDH

PCDHB8

116

Q9UN66
ESFEELENHDTDIFN

RP1

1466

P56715
FFNDLEDCDQIHVDD

EYA2

321

O00167
DVEEVKDQFATHEAF

UTRN

341

P46939
DTLVQEAIQAFHDNE

SPEF2

591

Q9C093
DSLVEHDEEFVQRQD

PRUNE2

561

Q8WUY3
HFDELEDVFLLETDN

SEMA3C

301

Q99985
LITEENEEEHNFFLA

NBN

251

O60934
QQDHFFQAAFLEERD

PLEK

76

P08567
DAAENLFQELQEHFQ

HSBP1L1

16

C9JCN9
EADVLEVDQGFDDHN

GANAB

406

Q14697
NFVLGRFEHIEDDDE

ENTPD4

231

Q9Y227
ENFANHLEEVFITVE

FSD2

231

A1L4K1
NFFDDDNHRQVLEEI

SMG1

3006

Q96Q15
VEFDYQAQHDDELTI

SH3KBP1

6

Q96B97
DAVDIEHENNNRFEE

RNF220

341

Q5VTB9
HQHLEEEFISEVENA

IMPG2

266

Q9BZV3
VFDENEDVNFDHFEI

STK32A

11

Q8WU08
LASFAHIEEENFVNE

PLA2R1

706

Q13018
NFDNTFEIHDDIEVL

TFDP2

301

Q14188
DEYFANLDHIESVEN

SETDB1

851

Q15047
HITNFLFEDFVEVDD

SMCR8

366

Q8TEV9
VFDDKEDVNFDHFQI

STK32C

81

Q86UX6
AVEQVLQEEHFDASH

APEH

566

P13798
DFHEQIADLQAQIAE

MYH11

1066

P35749
DQHQLDTILFFDEAN

RNF213

2476

Q63HN8
DFCFQEIEKDIHNFE

ZNF321P

31

Q8N8H1
NFDNTFEIHDDIEVL

TFDP1

286

Q14186
LNEDEILHFAVAEAD

NME8

56

Q8N427
VQFEDVRDAEDALHN

SRSF10

56

O75494
DDDSNFHVDFVVAAA

UBA7

811

P41226
LSFILDHVFIEQDDD

STAG2

826

Q8N3U4
DAELNVFYEESVHFD

XYLB

26

O75191
AARDHVFSFDLQAEE

SEMA6C

76

Q9H3T2
GFQHFESEEDINVAA

STAB2

2491

Q8WWQ8
DVEVQEHYDSFFEEV

U2AF1L4

71

Q8WU68
LNEDIFIVDQHATDE

PMS2

691

P54278
AFQHLSEAVQAAEEE

PRKDC

3381

P78527
VFDENEEVNFDHFQI

STK32B

11

Q9NY57
SVAFEDVAVNFTHEE

ZNF44

51

P15621
AEDKVFNEIRNEHFS

VPS33B

281

Q9H267
AEQHFADVVLSEEFL

KLHL2

181

O95198
HAPFEAENEDDLFEA

PRKCH

551

P24723
DDDIFEEDENFLVHL

SLC8A1

481

P32418