Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	CTP synthase activity	CTPS2 CTPS1	4.21e-05	2	130	2	GO:0003883
GeneOntologyBiologicalProcess	regulation of fatty acid beta-oxidation	ACACB CPT1A PLIN5 ABCD1	1.37e-05	24	128	4	GO:0031998
GeneOntologyBiologicalProcess	'de novo' CTP biosynthetic process	CTPS2 CTPS1	3.82e-05	2	128	2	GO:0044210
GeneOntologyBiologicalProcess	regulation of chromosome organization	SMG1 NCAPD3 ERCC4 SLF1 NUMA1 WDHD1 CDC16 CDC6 TASOR	4.32e-05	266	128	9	GO:0033044
GeneOntologyBiologicalProcess	positive regulation of fatty acid beta-oxidation	CPT1A PLIN5 ABCD1	6.38e-05	13	128	3	GO:0032000
GeneOntologyBiologicalProcess	positive regulation of axonogenesis	L1CAM TWF2 MACF1 ROBO2 PLXNA1 PLXNA2	7.83e-05	114	128	6	GO:0050772
GeneOntologyBiologicalProcess	chromosome organization	SMG1 NCAPD3 ERCC4 SLF1 KAT6A NUMA1 ESCO1 ITPA RIF1 WDHD1 CDC16 CDC6 TASOR TOP3B	9.36e-05	686	128	14	GO:0051276
GeneOntologyCellularComponent	cytoophidium	CTPS2 CTPS1	1.09e-04	3	127	2	GO:0097268
Domain	FN3_dom	PAPPA2 KALRN L1CAM IL20RA PTPRM ROBO2 ASTN1 IL23R IL7R	1.08e-05	209	124	9	IPR003961
Domain	Ig-like_fold	PAPPA2 TRIO KALRN L1CAM IL20RA SLC4A2 MST1R HMCN1 PTPRM ROBO2 ASTN1 ADGRF3 PLXNA1 PLXNA2 IL23R IL7R	1.78e-05	706	124	16	IPR013783
Domain	CTP_synthase_N	CTPS2 CTPS1	4.37e-05	2	124	2	IPR017456
Domain	GATase1_CTP_Synthase	CTPS2 CTPS1	4.37e-05	2	124	2	IPR033828
Domain	CTP_synthase	CTPS2 CTPS1	4.37e-05	2	124	2	IPR004468
Domain	CTP_synth_N	CTPS2 CTPS1	4.37e-05	2	124	2	PF06418
Domain	FN3	KALRN L1CAM IL20RA PTPRM ROBO2 ASTN1 IL23R IL7R	5.53e-05	199	124	8	PS50853
Domain	Clathrin/coatomer_adapt-like_N	COPG2 AP1G1 AP4B1	1.23e-04	15	124	3	IPR002553
Domain	Adaptin_N	COPG2 AP1G1 AP4B1	1.23e-04	15	124	3	PF01602
Domain	Arp3_met	ACTR3B ACTR3	1.31e-04	3	124	2	IPR015623
Domain	FBN	FBN1 FBN2	1.31e-04	3	124	2	IPR011398
Domain	-	PAPPA2 TRIO KALRN L1CAM IL20RA MST1R HMCN1 PTPRM ROBO2 ASTN1 PLXNA1 PLXNA2 IL23R IL7R	1.31e-04	663	124	14	2.60.40.10
Domain	PSI	ITGB7 MST1R PLXNA1 PLXNA2	2.05e-04	44	124	4	IPR016201
Domain	FN3	PAPPA2 KALRN L1CAM PTPRM ROBO2 ASTN1 IL23R	2.37e-04	185	124	7	SM00060
Domain	PSI	ITGB7 MST1R PLXNA1 PLXNA2	2.43e-04	46	124	4	SM00423
Domain	Neural_cell_adh	HMCN1 ROBO2	2.60e-04	4	124	2	IPR009138
Domain	HAT_MYST-type	KAT6A KAT6B	4.32e-04	5	124	2	IPR002717
Domain	MOZ_SAS	KAT6A KAT6B	4.32e-04	5	124	2	PF01853
Domain	GATase	CTPS2 CTPS1	4.32e-04	5	124	2	PF00117
Domain	MYST_HAT	KAT6A KAT6B	4.32e-04	5	124	2	PS51726
Domain	ARM-type_fold	SMG1 NCAPD3 MYBBP1A COPG2 MAP3K1 RIF1 AP1G1 AP4B1 TARBP1	4.38e-04	339	124	9	IPR016024
Domain	Spectrin	TRIO KALRN MACF1	4.59e-04	23	124	3	PF00435
Domain	GOLGA6L	GOLGA6L10 GOLGA6L9	6.45e-04	6	124	2	IPR026737
Domain	GATASE_TYPE_1	CTPS2 CTPS1	6.45e-04	6	124	2	PS51273
Domain	GATASE	CTPS2 CTPS1	6.45e-04	6	124	2	IPR017926
Domain	cEGF	FBN1 FBN2 HMCN1	6.64e-04	26	124	3	PF12662
Domain	cEGF	FBN1 FBN2 HMCN1	6.64e-04	26	124	3	IPR026823
Domain	IPT	MST1R PLXNA1 PLXNA2	7.44e-04	27	124	3	SM00429
Domain	fn3	KALRN L1CAM PTPRM ROBO2 IL23R IL7R	7.46e-04	162	124	6	PF00041
Domain	TB	FBN1 FBN2	8.98e-04	7	124	2	PF00683
Domain	Spectrin_repeat	TRIO KALRN MACF1	9.20e-04	29	124	3	IPR002017
Domain	Semap_dom	MST1R PLXNA1 PLXNA2	1.12e-03	31	124	3	IPR001627
Domain	SEMA	MST1R PLXNA1 PLXNA2	1.12e-03	31	124	3	PS51004
Domain	TIG	MST1R PLXNA1 PLXNA2	1.12e-03	31	124	3	PF01833
Domain	Sema	MST1R PLXNA1 PLXNA2	1.12e-03	31	124	3	SM00630
Domain	Sema	MST1R PLXNA1 PLXNA2	1.12e-03	31	124	3	PF01403
Domain	-	FBN1 FBN2	1.19e-03	8	124	2	3.90.290.10
Domain	Coatomer/calthrin_app_sub_C	COPG2 AP4B1	1.19e-03	8	124	2	IPR009028
Domain	IPT	MST1R PLXNA1 PLXNA2	1.23e-03	32	124	3	IPR002909
Domain	Plexin_repeat	MST1R PLXNA1 PLXNA2	1.23e-03	32	124	3	IPR002165
Domain	SPEC	TRIO KALRN MACF1	1.23e-03	32	124	3	SM00150
Domain	PSI	MST1R PLXNA1 PLXNA2	1.23e-03	32	124	3	PF01437
Domain	Spectrin/alpha-actinin	TRIO KALRN MACF1	1.23e-03	32	124	3	IPR018159
Domain	EGF_CA	FBN1 FBN2 PROZ HMCN1 AGRN	1.33e-03	122	124	5	SM00179
Domain	EGF-like_Ca-bd_dom	FBN1 FBN2 PROZ HMCN1 AGRN	1.43e-03	124	124	5	IPR001881
Domain	BTK	RASA2 RASAL1	1.53e-03	9	124	2	SM00107
Domain	Plexin_cytopl	PLXNA1 PLXNA2	1.53e-03	9	124	2	PF08337
Domain	TB_dom	FBN1 FBN2	1.53e-03	9	124	2	IPR017878
Domain	Znf_Btk_motif	RASA2 RASAL1	1.53e-03	9	124	2	IPR001562
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA1 PLXNA2	1.53e-03	9	124	2	IPR013548
Domain	Plexin	PLXNA1 PLXNA2	1.53e-03	9	124	2	IPR031148
Domain	BTK	RASA2 RASAL1	1.53e-03	9	124	2	PF00779
Domain	ZF_BTK	RASA2 RASAL1	1.53e-03	9	124	2	PS51113
Domain	TB	FBN1 FBN2	1.53e-03	9	124	2	PS51364
Domain	EGF_1	ITGB7 FBN1 FBN2 PROZ HMCN1 ASTN1 AGRN	1.58e-03	255	124	7	PS00022
Domain	EGF-like_CS	ITGB7 FBN1 FBN2 PROZ HMCN1 ASTN1 AGRN	1.80e-03	261	124	7	IPR013032
Domain	-	CTPS2 CTPS1	1.90e-03	10	124	2	3.40.50.880
Domain	EGF_2	ITGB7 FBN1 FBN2 PROZ HMCN1 ASTN1 AGRN	1.97e-03	265	124	7	PS01186
Domain	ARM-like	SMG1 NCAPD3 COPG2 RIF1 AP1G1 AP4B1 TARBP1	2.19e-03	270	124	7	IPR011989
Domain	PNMA	MOAP1 PNMA8B	2.31e-03	11	124	2	IPR026523
Domain	PNMA	MOAP1 PNMA8B	2.31e-03	11	124	2	PF14893
Domain	Coatomer/clathrin_app_Ig-like	COPG2 AP1G1	2.76e-03	12	124	2	IPR013041
Domain	Class_I_gatase-like	CTPS2 CTPS1	2.76e-03	12	124	2	IPR029062
Domain	Rho_GTPase_activation_prot	RASA2 PLXNA1 PLXNA2 RASAL1	2.81e-03	88	124	4	IPR008936
Domain	H15	KAT6A KAT6B	3.25e-03	13	124	2	SM00526
Domain	H15	KAT6A KAT6B	3.25e-03	13	124	2	PS51504
Domain	Histone_H1/H5_H15	KAT6A KAT6B	3.78e-03	14	124	2	IPR005818
Domain	RasGAP	RASA2 RASAL1	3.78e-03	14	124	2	SM00323
Domain	P_typ_ATPase_c	ATP9B ATP11B	3.78e-03	14	124	2	IPR032630
Domain	P-type_ATPase_N	ATP9B ATP11B	3.78e-03	14	124	2	IPR032631
Domain	P-type_ATPase_IV	ATP9B ATP11B	3.78e-03	14	124	2	IPR006539
Domain	PhoLip_ATPase_C	ATP9B ATP11B	3.78e-03	14	124	2	PF16212
Domain	PhoLip_ATPase_N	ATP9B ATP11B	3.78e-03	14	124	2	PF16209
Domain	RasGAP_CS	RASA2 RASAL1	3.78e-03	14	124	2	IPR023152
Domain	PH	RASA2 TRIO KALRN KIF1B PLEKHA1 RASAL1	4.28e-03	229	124	6	PF00169
Domain	RasGAP	RASA2 RASAL1	4.34e-03	15	124	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA2 RASAL1	4.34e-03	15	124	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	RASA2 RASAL1	4.34e-03	15	124	2	PS50018
Domain	ASX_HYDROXYL	FBN1 FBN2 PROZ HMCN1	4.44e-03	100	124	4	PS00010
Domain	EGF	FBN1 FBN2 PROZ HMCN1 ASTN1 AGRN	4.85e-03	235	124	6	SM00181
Domain	EGF_3	FBN1 FBN2 PROZ HMCN1 ASTN1 AGRN	4.85e-03	235	124	6	PS50026
Domain	-	RASA2 RASAL1	4.94e-03	16	124	2	1.10.506.10
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN1 FBN2 PROZ HMCN1	5.46e-03	106	124	4	IPR000152
Domain	GOLGA2L5	GOLGA6L10 GOLGA6L9	6.24e-03	18	124	2	PF15070
Domain	Golgin_A	GOLGA6L10 GOLGA6L9	6.24e-03	18	124	2	IPR024858
Domain	RasGAP_dom	RASA2 RASAL1	6.24e-03	18	124	2	IPR001936
Domain	Actin/actin-like_CS	ACTR3B ACTR3	6.24e-03	18	124	2	IPR020902
Domain	EGF-like_dom	FBN1 FBN2 PROZ HMCN1 ASTN1 AGRN	6.39e-03	249	124	6	IPR000742
Pubmed	Molecular analysis of spontaneous somatic mutants.	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7	9.58e-10	5	131	4	401950
Pubmed	1.3 A X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization.	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7	2.54e-07	15	131	4	12657787
Pubmed	Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7	5.65e-07	18	131	4	6788376
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TICRR MYBBP1A ERCC4 ERP44 RASA2 COPG2 DUS3L STAT1 C2CD5 PPP6C WDHD1 AP1G1 SOCS5 MASTL MACF1 TASOR AGRN	7.27e-07	1084	131	17	11544199
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SMG1 MYBBP1A ERCC4 NUMA1 FYCO1 MED1 C2CD5 NUP205 UBR5 CDC16 ZBTB11	9.55e-07	440	131	11	34244565
Pubmed	Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system.	COPG2 AP1G1 AP4B1	1.04e-06	6	131	3	11409905
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	TICRR NCAPD3 MYBBP1A KAT6A NUMA1 MED1 MAP3K1 NUP205 RIF1 MACF1 CDC6 ZBTB11 TASOR TOP3B	1.15e-06	759	131	14	35915203
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 NCAPD3 ERCC4 SLC4A2 AP1G1 DSTYK MARF1 KMT2A FKBP8 AP4B1 ZBTB11 TASOR AGRN	1.17e-06	650	131	13	38777146
Pubmed	Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7	1.33e-06	22	131	4	2499654
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	L1CAM PLXNA1 PLXNA2	1.81e-06	7	131	3	19063725
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	VPS13C ATP9B REV3L ESCO1 HMCN1 MACF1 AGRN	1.88e-06	152	131	7	34299191
Pubmed	Defining the membrane proteome of NK cells.	NCAPD3 MYBBP1A FYCO1 PSMD13 MED1 CPT1A ITGB7 ACTR3 SLC4A2 NUP205 ATP11B AP1G1 UBR5 MARF1 ABCD1 FKBP8 CTPS1	2.00e-06	1168	131	17	19946888
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	NCAPD3 MYBBP1A ERP44 COPG2 CPT1A SLC4A2 NUP205 TRAFD1 CTPS2 PPP6C AP1G1 UBR5 ABCD1 FKBP8 TARBP1	2.85e-06	942	131	15	31073040
Pubmed	Trio GEF mediates RhoA activation downstream of Slit2 and coordinates telencephalic wiring.	TRIO L1CAM ROBO2	2.88e-06	8	131	3	30177526
Pubmed	The role of neuropilins in cell signalling.	L1CAM PLXNA1 PLXNA2	4.31e-06	9	131	3	19909241
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	MYBBP1A ERCC4 NUMA1 NUP205 AP1G1 UBR5 CDC16 CTPS1	7.26e-06	262	131	8	36880596
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	ERP44 KIF1B TWF2 PSMD13 DUS3L ME1 ACTR3 STAT1 NUP205 CTPS2 PPP6C WDHD1 AP1G1 ANP32E MACF1 CTPS1 RASAL1 GABPA	9.29e-06	1455	131	18	22863883
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MYBBP1A TRIO COPG2 PSMD13 ITGA5 ME1 ACTR3 CTDSP2 PTPDC1 RIF1 PPP6C PTPRM PLEKHA1 FKBP8 TOP3B	1.03e-05	1049	131	15	27880917
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	VPS13C NUMA1 COPG2 TWF2 CPT1A STAT1 UBR5 MOB3B PLEKHA1 ABCD1 FKBP8	1.09e-05	568	131	11	37774976
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	1.41e-05	2	131	2	12399449
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	1.41e-05	2	131	2	21851253
Pubmed	Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.	PLXNA1 PLXNA2	1.41e-05	2	131	2	10781943
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	1.41e-05	2	131	2	30044367
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	1.41e-05	2	131	2	21440062
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	1.41e-05	2	131	2	15131124
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	1.41e-05	2	131	2	20404337
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	1.41e-05	2	131	2	8791520
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	1.41e-05	2	131	2	8307578
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	1.41e-05	2	131	2	7744963
Pubmed	Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation.	PRSS12 AGRN	1.41e-05	2	131	2	17586728
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	1.41e-05	2	131	2	26408953
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	1.41e-05	2	131	2	18006876
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	1.41e-05	2	131	2	24833718
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	1.41e-05	2	131	2	24265020
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	1.41e-05	2	131	2	20529844
Pubmed	ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.	KAT6A KAT6B	1.41e-05	2	131	2	39505971
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	1.41e-05	2	131	2	23133647
Pubmed	Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.	FBN1 FBN2	1.41e-05	2	131	2	1852206
Pubmed	Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets.	ACACB CPT1A	1.41e-05	2	131	2	12920182
Pubmed	Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.	TRIO KALRN	1.41e-05	2	131	2	26858404
Pubmed	The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.	KAT6A KAT6B	1.41e-05	2	131	2	24150941
Pubmed	Selective loss of basal but not receptor-stimulated relaxation by endothelial nitric oxide synthase after isolation of the mouse aorta.	FBN1 NOS3	1.41e-05	2	131	2	23022329
Pubmed	Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.	FBN1 FBN2	1.41e-05	2	131	2	12429739
Pubmed	Neurotrypsin cleaves agrin locally at the synapse.	PRSS12 AGRN	1.41e-05	2	131	2	18230682
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	1.41e-05	2	131	2	12524050
Pubmed	ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells.	ACTR3B ACTR3	1.41e-05	2	131	2	10806390
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	1.41e-05	2	131	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	1.41e-05	2	131	2	35419902
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	1.41e-05	2	131	2	10504303
Pubmed	Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.	KAT6A KAT6B	1.41e-05	2	131	2	27185879
Pubmed	Pleiotropic activation of endothelial function by angiotensin II receptor blockers is crucial to their protective anti-vascular remodeling effects.	FBN1 NOS3	1.41e-05	2	131	2	35697767
Pubmed	Genes encoding agrin (AGRN) and neurotrypsin (PRSS12) are associated with muscle mass, strength and plasma C-terminal agrin fragment concentration.	PRSS12 AGRN	1.41e-05	2	131	2	36609795
Pubmed	A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.	BPIFB4 NOS3	1.41e-05	2	131	2	28852218
Pubmed	Destabilization of the neuromuscular junction by proteolytic cleavage of agrin results in precocious sarcopenia.	PRSS12 AGRN	1.41e-05	2	131	2	21885656
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	1.41e-05	2	131	2	25524144
Pubmed	The C-Terminal Fragment of Agrin (CAF), a Novel Marker of Renal Function, Is Filtered by the Kidney and Reabsorbed by the Proximal Tubule.	PRSS12 AGRN	1.41e-05	2	131	2	27380275
Pubmed	Coincident pre- and postsynaptic activation induces dendritic filopodia via neurotrypsin-dependent agrin cleavage.	PRSS12 AGRN	1.41e-05	2	131	2	19303856
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	1.41e-05	2	131	2	16407178
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	1.41e-05	2	131	2	10359653
Pubmed	Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.	CTPS2 CTPS1	1.41e-05	2	131	2	20739275
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	NCAPD3 MYBBP1A NUMA1 COPG2 ACTR3 NUP205 CTPS2 WDHD1 AP1G1 UBR5 ANP32E CTPS1	1.53e-05	704	131	12	29955894
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	NCAPD3 MYBBP1A NUMA1 TRAFD1 UBR5 CDC16 KMT2A	1.57e-05	210	131	7	16565220
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACACB NUMA1 PSMD13 ME1 TRAFD1 KMT2A ADGRF3 FKBP8 CTPS1 TOP3B	2.00e-05	497	131	10	36774506
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	NCAPD3 MYBBP1A ERP44 PSMD13 CPT1A STAT1 ITPA NUP205 RIF1 TRAFD1 CTPS2 PPP6C UBR5 FKBP8 CDC6 CTPS1	2.16e-05	1257	131	16	37317656
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	COPG2 PSMD13 ACTR3 PPP6C WDHD1 UBR5 MOB3B FKBP8 CTPS1	2.17e-05	399	131	9	37536630
Pubmed	Human transcription factor protein interaction networks.	SMG1 MYBBP1A ERCC4 SLF1 ACACB NUMA1 PSMD13 ACTR3 STAT1 NUP205 RIF1 FBN1 FBN2 PPP6C MARF1 KMT2A GABPA	2.76e-05	1429	131	17	35140242
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MYBBP1A ERP44 KIF1B COPG2 TWF2 PSMD13 ACTR3B ACTR3 STAT1 C2CD5 NUP205 UBR5 DSTYK MOB3B AP4B1 CTPS1	2.79e-05	1284	131	16	17353931
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	ERP44 ACACB VPS13C COPG2 TWF2 ACTR3 C2CD5 TRAFD1 WDHD1 AP1G1 PLEKHA1 FKBP8 CDC6 GABPA	2.82e-05	1007	131	14	34597346
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	VPS13C RNF17 ITPA NUP205 AP1G1 UBR5 CDC16 ASTN1 ABCD1 FKBP8 CTPS1 TASOR	2.98e-05	754	131	12	35906200
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NCAPD3 MYBBP1A KIF1B NUMA1 MED1 C2CD5 RIF1 TRAFD1 WDHD1 KMT2A CTPS1 KAT6B	3.84e-05	774	131	12	15302935
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	ITGA5 FBN1 FBN2 AGRN	3.87e-05	50	131	4	23658023
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	ACACB DUS3L ITPA PPP6C CDC6 TASOR TOP3B	3.89e-05	242	131	7	34011540
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	COPG2 FYCO1 ACTR3B ACTR3 STAT1 MAP3K1 PTPDC1 TRAFD1 CTPS2 PPP6C WDHD1 AP1G1 UBR5 AP4B1	3.92e-05	1038	131	14	26673895
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA1 PLXNA2	4.21e-05	3	131	2	27397516
Pubmed	STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis.	STAT1 IL23R	4.21e-05	3	131	2	22195034
Pubmed	Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.	FBN1 FBN2	4.21e-05	3	131	2	10825173
Pubmed	Induction of BAFF expression by IFN-γ via JAK/STAT signaling pathways in human intestinal epithelial cells.	STAT1 TNFSF13B	4.21e-05	3	131	2	23271704
Pubmed	Expression of Human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A.	CTPS2 CTPS1	4.21e-05	3	131	2	16179339
Pubmed	Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.	TRIO KALRN	4.21e-05	3	131	2	31801062
Pubmed	Construction of a D2.B6-Fv-2r congenic mouse strain: nonlethality of the homozygous Fv-2' genotype.	ME1 MST1R	4.21e-05	3	131	2	6939921
Pubmed	H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts.	STAT1 SOCS5	4.21e-05	3	131	2	33391546
Pubmed	Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.	PLXNA1 PLXNA2	4.21e-05	3	131	2	29091353
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	FBN1 FBN2	4.21e-05	3	131	2	30201140
Pubmed	Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.	PLXNA1 PLXNA2	4.21e-05	3	131	2	36169302
Pubmed	GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells.	GABPA IL7R	4.21e-05	3	131	2	15361867
Pubmed	SlitC-PlexinA1 mediates iterative inhibition for orderly passage of spinal commissural axons through the floor plate.	L1CAM PLXNA1	4.21e-05	3	131	2	33345773
Pubmed	Plasmin-sensitive dibasic sequences in the third fibronectin-like domain of L1-cell adhesion molecule (CAM) facilitate homomultimerization and concomitant integrin recruitment.	L1CAM ITGA5	4.21e-05	3	131	2	10871287
Pubmed	Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.	KAT6A KAT6B	4.21e-05	3	131	2	23063713
Pubmed	Regulation of Aurora-A kinase gene expression via GABP recruitment of TRAP220/MED1.	MED1 GABPA	4.21e-05	3	131	2	16574658
Pubmed	HIV Nef promotes expression of B-lymphocyte stimulator by blood dendritic cells during HIV infection in humans.	STAT1 TNFSF13B	4.21e-05	3	131	2	25378636
Pubmed	Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.	FBN1 FBN2	4.21e-05	3	131	2	20855508
Pubmed	MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.	KAT6A KAT6B	4.21e-05	3	131	2	36754959
Pubmed	Identification of plexin family molecules in mice.	PLXNA1 PLXNA2	4.21e-05	3	131	2	8806646
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA1 PLXNA2	4.21e-05	3	131	2	18625214
Pubmed	Murine BAFF expression is up-regulated by estrogen and interferons: implications for sex bias in the development of autoimmunity.	STAT1 TNFSF13B	4.21e-05	3	131	2	22784990
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA1 PLXNA2	4.21e-05	3	131	2	11241833
Pubmed	Inhibition of Marfan Syndrome Aortic Root Dilation by Losartan: Role of Angiotensin II Receptor Type 1-Independent Activation of Endothelial Function.	FBN1 NOS3	4.21e-05	3	131	2	29433732
Pubmed	Higher-order immunoglobulin repertoire restrictions in CLL: the illustrative case of stereotyped subsets 2 and 169.	IGHV3-48 IGHV3-21	4.21e-05	3	131	2	33036024
Pubmed	Combination analysis of NOS3, ABCB1 and IL23R polymorphisms with alcohol-induced osteonecrosis of the femoral head risk in Chinese males.	NOS3 IL23R	4.21e-05	3	131	2	28422712
Pubmed	LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism.	BPIFB4 NOS3	4.21e-05	3	131	2	28419216
Interaction	DVL2 interactions	VPS13C NUMA1 ATP9B PSMD13 REV3L ESCO1 ACTR3 MAP3K1 MST1R HMCN1 AP1G1 MACF1 FKBP8 AGRN TOP3B	2.59e-06	557	128	15	int:DVL2
GeneFamily	Fibronectin type III domain containing	KALRN L1CAM PTPRM ROBO2 ASTN1 IL7R	1.22e-04	160	87	6	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	TRIO KALRN L1CAM HMCN1 PTPRM ROBO2	1.27e-04	161	87	6	593
GeneFamily	Plexins	PLXNA1 PLXNA2	8.06e-04	9	87	2	683
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA2 RASAL1	1.00e-03	10	87	2	830
GeneFamily	Paraneoplastic Ma antigens	MOAP1 PNMA8B	1.22e-03	11	87	2	671
GeneFamily	ATPase phospholipid transporting	ATP9B ATP11B	2.31e-03	15	87	2	1210
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	KAT6A KAT6B	2.63e-03	16	87	2	66
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT6A KAT6B	2.97e-03	17	87	2	486
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	SMG1 SLF1 RASA2 VPS13C KAT6A NUMA1 TWF2 REV3L MED1 ITGB7 ACTR3 STAT1 SLC5A3 RIF1 ATP11B UBR5 CDC16 DSTYK KMT2A ANP32E MACF1 AP4B1 KAT6B TASOR GABPA IL7R	1.75e-08	1492	130	26	M40023
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	TRIO KAT6A REV3L MED1 C2CD5 RIF1 ATP11B WDHD1 PTPRM UBR5 CDC16 SOCS5 MACF1 KAT6B ZBTB11 TASOR IL7R	1.20e-06	856	130	17	M4500
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	DDR1 ERCC4 TRIO KALRN KIF1B FYCO1 CPT1A STAT1 SLC5A3 ZSCAN29 PTPDC1 PTPRM TBC1D22A MARF1 MASTL MOB3B PLEKHA1 ASTN1 FKBP8	2.20e-06	1102	130	19	M2369
Coexpression	YAGI_AML_WITH_T_8_21_TRANSLOCATION	SMG1 DDR1 ZNF274 TRIO NUMA1 PROZ SOCS5 KMT2A MACF1 FKBP8 AGRN	2.62e-06	372	130	11	M19261
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	DDR1 ERCC4 TRIO KALRN KIF1B FYCO1 CPT1A STAT1 SLC5A3 ZSCAN29 PTPDC1 PTPRM TBC1D22A MARF1 MASTL MOB3B PLEKHA1 ASTN1 FKBP8	2.93e-06	1124	130	19	MM1070
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	SMG1 RASA2 KALRN KAT6A MAP3K1 RIF1 KMT2A MACF1	4.83e-06	189	130	8	M3112
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7 ME1 MAP3K1	1.21e-05	102	130	6	MM872
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	TRIO KAT6A REV3L C2CD5 ATP11B UBR5 SOCS5 MARF1 KAT6B TASOR IL7R	2.17e-05	466	130	11	M13522
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_NEGATIVE	SMG1 ZNF274 NUMA1 ATP9B MED1 MAP3K1 RIF1 ATP11B AP1G1 KAT6B ZBTB11	2.54e-05	474	130	11	M40991
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP	ATP9B STAT1 RIF1 UBR5 MARF1 MOB3B MACF1	3.83e-05	184	130	7	M9005
Coexpression	LEE_BMP2_TARGETS_DN	NCAPD3 MYBBP1A SLF1 PRSS12 ME1 POF1B MOAP1 NUP205 RIF1 WDHD1 ANP32E BMPER CDC6 CTPS1 TARBP1	4.37e-05	904	130	15	M2325
Coexpression	LEE_BMP2_TARGETS_DN	NCAPD3 MYBBP1A SLF1 PRSS12 ME1 POF1B MOAP1 NUP205 RIF1 WDHD1 ANP32E BMPER CDC6 CTPS1 TARBP1	5.46e-05	922	130	15	MM1068
Coexpression	GSE12366_GC_VS_NAIVE_BCELL_DN	ZNF274 VPS13C STAT1 MAP3K1 MOB3B PLEKHA1 MACF1	5.53e-05	195	130	7	M3170
Coexpression	GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP	KIF1B NUMA1 CTDSP2 PTPRM DSTYK TASOR TARBP1	5.71e-05	196	130	7	M4530
Coexpression	GSE12366_GC_VS_MEMORY_BCELL_DN	ZNF274 STAT1 MAP3K1 MOB3B PLEKHA1 MACF1 CD99L2	5.90e-05	197	130	7	M3173
Coexpression	GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN	ATP9B RNF17 CTDSP2 SLC8A2 PLEKHA1 AGRN PLXNA1	6.29e-05	199	130	7	M3445
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	ZNF274 PRSS12 COPG2 ITGB7 MAP3K1 DSTYK SOCS5	6.49e-05	200	130	7	M9121
Coexpression	BMI1_DN.V1_UP	TRIO ITGA5 KMT2A AGRN PLXNA2 IL7R	9.46e-05	147	130	6	M2782
Coexpression	DING_LUNG_CANCER_BY_MUTATION_RATE	SMG1 DDR1 ROBO2	1.28e-04	20	130	3	M1189
Coexpression	DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP	TICRR MYBBP1A WDHD1 MACF1 CDC6 CTPS1 ECE2	1.47e-04	228	130	7	M2151
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	PCSK1 TICRR NCAPD3 SLF1 REV3L C2CD5 NUP205 PTPDC1 RIF1 WDHD1 CDC6 CTPS1	1.50e-04	680	130	12	MM456
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	ZNF274 RASA2 KIF1B KAT6A ESCO1 CTDSP2 RIF1 ATP11B PPP6C AP1G1 MARF1 ZBTB11	1.50e-04	680	130	12	M41089
Coexpression	XU_CREBBP_TARGETS_DN	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7	1.74e-04	56	130	4	MM642
Coexpression	GSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_UP	VPS13C KIF1B KAT6A REV3L RIF1 ASTN1	1.84e-04	166	130	6	M9015
Coexpression	SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12	IGHV3-21 ERP44 IGHV3-7 L1CAM MED1 NPEPL1 PROZ KAT6B	1.94e-04	318	130	8	M2429
Coexpression	CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP	PCSK1 SMG1 PRSS12 KIF1B PSMD13 ME1 TOP3B	1.96e-04	239	130	7	M4716
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	TICRR NCAPD3 ACTR3B NUP205 RIF1 WDHD1 MASTL PLEKHA1 CDC6 CTPS1	4.08e-06	258	129	10	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	NCAPD3 COPG2 ACTR3B RNF17 NUP205 RIF1 WDHD1 UBR5 PLEKHA1 CTPS1	3.72e-05	333	129	10	gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLF1 TRIO DIPK2B HMCN1 PTPRM UBR5 KMT2A MACF1 IL7R	8.38e-09	200	131	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TICRR IL20RA RNF17 ITGB7 WDHD1 IL23R IL7R	5.98e-07	165	131	7	26c750f10f6401752e2e63d91dc844c81b29d735
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 VPS13C KAT6A KMT2A MACF1 TASOR IL7R	1.24e-06	184	131	7	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C KIF1B REV3L RIF1 KMT2A MACF1 ROBO2	1.83e-06	195	131	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C KIF1B REV3L RIF1 KMT2A MACF1 ROBO2	1.83e-06	195	131	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	PAPPA2 SMG1 SLF1 KMT2A MACF1 IL7R	5.72e-06	151	131	6	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN DIPK2B PTPRM KRT222 BPIFB4 NOS3	6.90e-06	156	131	6	f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	VPS13C MED1 POF1B NUP205 CDC16 CD99L2	1.29e-05	174	131	6	feed99acd868db61f045e666dbfdcaed91ca1488
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL24A1 FBN1 HMCN1 MACF1 ROBO2 BMPER	1.33e-05	175	131	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	BAL-Control-cDC_1\|Control / Compartment, Disease Groups and Clusters	RNF17 STAT1 FBN2 TNFSF13B MASTL GOLGA6L9	1.42e-05	177	131	6	aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 VPS13C L1CAM ITGB7 TASOR IL7R	1.61e-05	181	131	6	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRIO KALRN REV3L ME1 COL24A1 ROBO2	1.66e-05	182	131	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	L1CAM STAT1 SLC5A3 FBN1 AGRN RASAL1	1.82e-05	185	131	6	a6874dd3030d04380cc3c01de1069461aad4ef45
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SMG1 MED1 MAP3K1 HMCN1 MARF1 GABPA	1.88e-05	186	131	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 VPS13C AP1G1 KMT2A MACF1 ZBTB11	1.99e-05	188	131	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	SLC5A3 FBN1 HMCN1 MACF1 ROBO2 BMPER	2.05e-05	189	131	6	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TICRR NCAPD3 WDHD1 MASTL ANP32E CDC6	2.05e-05	189	131	6	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	PBMC-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	NCAPD3 SLF1 NUP205 RIF1 WDHD1 CDC6	2.11e-05	190	131	6	84ee185939bdefb10705b621a70da27701eadcee
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASA2 VPS13C ESCO1 POF1B ACTR3 TASOR	2.18e-05	191	131	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASA2 VPS13C ESCO1 POF1B ACTR3 TASOR	2.18e-05	191	131	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASA2 VPS13C ESCO1 POF1B ACTR3 TASOR	2.18e-05	191	131	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN ITGA5 DIPK2B FBN1 PTPRM NOS3	2.24e-05	192	131	6	1ee4783051ec94ea94600f040edcb385fc4289f1
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SMG1 ATP9B AP1G1 KMT2A MACF1 IL7R	2.24e-05	192	131	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS12 MST1R FBN1 HMCN1 BMPER CDC6	2.31e-05	193	131	6	59b8186d0221fba06a16157e9d148399ed801f38
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS12 MST1R FBN1 HMCN1 BMPER CDC6	2.31e-05	193	131	6	dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS12 MST1R FBN1 HMCN1 BMPER CDC6	2.31e-05	193	131	6	03678162648bd5b1d65a5450b60c8863edbf95c7
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KALRN MAP3K1 COL24A1 MACF1 ROBO2 BMPER	2.38e-05	194	131	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLF1 DIPK2B HMCN1 PTPRM MACF1 ROBO2	2.38e-05	194	131	6	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA5 DIPK2B FBN1 PTPRM BMPER NOS3	2.38e-05	194	131	6	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	LA-09._Endothelium_I\|World / Chamber and Cluster_Paper	KALRN DIPK2B HMCN1 PTPRM NOS3 PLXNA2	2.45e-05	195	131	6	fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN ITGA5 DIPK2B PTPRM NOS3 PLXNA2	2.45e-05	195	131	6	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA5 DIPK2B FBN1 PTPRM BMPER NOS3	2.45e-05	195	131	6	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	KALRN ITGA5 DIPK2B FBN1 PTPRM NOS3	2.52e-05	196	131	6	ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN ITGA5 DIPK2B PTPRM NOS3 PLXNA2	2.52e-05	196	131	6	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TICRR SLF1 WDHD1 MASTL CDC6 CTPS1	2.52e-05	196	131	6	df366d76ea55f49e349d622effa57c1535df8400
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN ITGA5 DIPK2B PTPRM NOS3 PLXNA2	2.52e-05	196	131	6	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SMG1 VPS13C TNFSF13B MACF1 IL23R IL7R	2.52e-05	196	131	6	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	3'-Child09-12-SmallIntestine-Endothelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA5 DIPK2B PTPRM PLIN5 KRT222 NOS3	2.59e-05	197	131	6	86a02fd7b4762b3278e5e60b5483b5fc1206e597
ToppCell	LA-09._Endothelium_I\|LA / Chamber and Cluster_Paper	KALRN DIPK2B HMCN1 PTPRM NOS3 PLXNA2	2.59e-05	197	131	6	ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ITGA5 DIPK2B HMCN1 PTPRM NOS3 PLXNA2	2.67e-05	198	131	6	7cddd474416651088a4e08edfc0ac420ff10a5fe
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ITGA5 POF1B DIPK2B FBN1 HMCN1 AGRN	2.74e-05	199	131	6	70e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCell	COVID-19-Lymphoid-Proliferating_CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	SNRNP25 NCAPD3 WDHD1 MASTL ANP32E CDC6	2.74e-05	199	131	6	2e9ee10a069afca5dbd9f0863cf90a66db1a6ffb
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	FBN2 HMCN1 PTPRM PLEKHA1 MACF1 IL7R	2.74e-05	199	131	6	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ITGA5 DIPK2B PTPRM PLEKHA1 AGRN NOS3	2.74e-05	199	131	6	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ITGA5 DIPK2B HMCN1 AGRN NOS3 PLXNA2	2.74e-05	199	131	6	463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	SLF1 KAT6A PTPRM KMT2A MACF1 IL7R	2.82e-05	200	131	6	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	REV3L DIPK2B PTPRM PLEKHA1 MACF1 IL7R	2.82e-05	200	131	6	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLF1 DIPK2B PTPRM MACF1 NOS3 IL7R	2.82e-05	200	131	6	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-mDC\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYBBP1A TWF2 ITGB7 ACTR3 TNFSF13B ANP32E	2.82e-05	200	131	6	f78968d4b4d907094b2c44dcf5ac557ae94e4484
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Notum))\|Striatum / BrainAtlas - Mouse McCarroll V32	PCDHGA4 CDC6 TARBP1 TMEM139	6.39e-05	73	131	4	50a8164d967f2706344adcdc1562dc08c9f16c8f
ToppCell	FLU-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	ITGB7 TNFSF13B PLXNA1 IL23R TMEM139	1.08e-04	159	131	5	97c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCell	FLU-Healthy-1\|FLU / Virus stimulation, Condition and Cluster	ITGB7 TNFSF13B PLXNA1 IL23R TMEM139	1.08e-04	159	131	5	fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 ITGB7 ACTR3 MOAP1 IL7R	1.08e-04	159	131	5	5c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 ITGB7 ACTR3 MOAP1 IL7R	1.21e-04	163	131	5	476e94e1d132eaaecb9e376bd32748a75ad22081
ToppCell	368C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	OLAH L1CAM TRAFD1 PLXNA1 IL7R	1.28e-04	165	131	5	9d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCell	3'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Paneth\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 IGHV3-7 KAT6A IL20RA CTPS2	1.32e-04	166	131	5	b64ab3d13b76bba3c305ebbfc96f983cd6ca30c9
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TICRR SLF1 CDC6 IL23R IL7R	1.32e-04	166	131	5	26f3d5e5e30b63b09b89cda23c423d12d887631f
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RNF17 ITGB7 CDC6 IL23R IL7R	1.35e-04	167	131	5	53e32d6687a07f486141df9f4ab998af4c03a507
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	PROZ TNFSF13B PLIN5 IL23R IL7R	1.39e-04	168	131	5	d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYBBP1A COPG2 DUS3L NUP205 ATP11B	1.47e-04	170	131	5	070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell	droplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ITGB7 HMCN1 MOB3B TOP3B	1.51e-04	171	131	5	e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SMG1 KAT6A MACF1 KAT6B IL7R	1.51e-04	171	131	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RASA2 TNFSF13B ANP32E IL23R IL7R	1.51e-04	171	131	5	6ab7f103cbdbd49ef687cbb8a42ddc5517af0f7f
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ITGB7 MOAP1 PTPRM IL23R IL7R	1.55e-04	172	131	5	a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCell	facs-GAT-Fat-18m-Lymphocytic-T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM RNF17 ITGB7 IL23R IL7R	1.55e-04	172	131	5	17a486c5d0430abb133eab9f087e2ef8b60f7d25
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAPD3 PTPDC1 RIF1 MASTL CDC6	1.55e-04	172	131	5	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DBX2 FBN1 PROZ HMCN1 GABPA	1.64e-04	174	131	5	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C ESCO1 HMCN1 MACF1 TASOR	1.73e-04	176	131	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7 ITGB7	1.78e-04	177	131	5	ae2d2e138946535596fa30a55207f261cafda461
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB7 PROZ ATP11B MASTL IL7R	1.82e-04	178	131	5	a9a8567d8fdc0fffd612fee16b5b29ef7b1c9307
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB7 PROZ ATP11B MASTL IL7R	1.82e-04	178	131	5	5ecbea15efd304057aef826ec2f385997bfaf0c9
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	GTDC1 MAP3K1 TRAFD1 TNFSF13B IL7R	1.92e-04	180	131	5	aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KALRN DIPK2B PTPRM MACF1 NOS3	1.92e-04	180	131	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR TWF2 ITGB7 CDC6 IL7R	1.92e-04	180	131	5	8cef63866c205df3825df84ce51fa61aa04ae491
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK1 IL20RA ITGB7 IL23R IL7R	1.97e-04	181	131	5	c7ad10a696d94b9ee91cd7e62761d356d5106eda
ToppCell	RV\|World / Chamber and Cluster_Paper	ACACB FBN2 PTPRM PLIN5 BMPER	1.97e-04	181	131	5	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	SMG1 AP1G1 UBR5 MACF1 IL7R	1.97e-04	181	131	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK1 IL20RA ITGB7 IL23R IL7R	1.97e-04	181	131	5	eaa3a2c268cce527004ae656d35e037b984fb4c7
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DIPK2B HMCN1 PTPRM AGRN NOS3	2.02e-04	182	131	5	997d37ca2af661c92a56add888762724dfccc890
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ITGA5 COL24A1 TNFSF13B IL23R IL7R	2.02e-04	182	131	5	b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA5 DIPK2B HMCN1 NOS3 PLXNA2	2.07e-04	183	131	5	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA5 DIPK2B HMCN1 NOS3 PLXNA2	2.07e-04	183	131	5	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS12 ITGB7 PROZ IL23R IL7R	2.07e-04	183	131	5	302bd0f1f8025f385a764f2a9adafdd7f1f67ea3
ToppCell	Posterior_cortex-Neuronal-Excitatory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KALRN PRSS12 ACTR3B SLC8A2 RASAL1	2.13e-04	184	131	5	25ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7 ITGB7	2.13e-04	184	131	5	15f2c10101ccc8ed059520fc082ee42593dff269
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7 ITGB7	2.13e-04	184	131	5	a90a58d9e319afa1cd572e4c2f516fadc42f56e5
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pre-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-7 RASAL1	2.18e-04	185	131	5	0fa7970709dc957dea95fabbd83263a0335babd5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN COL24A1 SLC8A2 BMPER RASAL1	2.23e-04	186	131	5	84ba666237c18189d7e7556bd92dd953af733c00
ToppCell	droplet-Spleen-nan-3m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ESCO1 MACF1 TASOR IL7R	2.23e-04	186	131	5	26f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CTDSP2 GOLGA6L10 DSTYK GOLGA6L9 TASOR	2.23e-04	186	131	5	bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RASA2 COL24A1 TNFSF13B IL23R IL7R	2.23e-04	186	131	5	855c2e5a8a6cf94c7de31982e0e2416f924439d3
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	FBN1 HMCN1 MACF1 ROBO2 BMPER	2.29e-04	187	131	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	COL24A1 FBN1 HMCN1 ROBO2 BMPER	2.29e-04	187	131	5	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-21 IGHV3-13 IGHV3-7 ITGB7 CDC6	2.35e-04	188	131	5	6844cebca177fdf38b21a40d606230a033717a3a
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA2 REV3L FBN2 PTPRM BMPER	2.35e-04	188	131	5	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 FBN1 HMCN1 BMPER NOS3	2.41e-04	189	131	5	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	COVID-19-Heart-EC_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KALRN DIPK2B PTPRM NOS3 PLXNA2	2.41e-04	189	131	5	fe49852ba15f948b384d6b4c258927c70b741357
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 MAP3K1 MST1R MOB3B PLEKHA1	2.41e-04	189	131	5	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA5 FBN1 PTPRM BMPER NOS3	2.41e-04	189	131	5	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA5 FBN1 HMCN1 BMPER NOS3	2.41e-04	189	131	5	b028466fcd36fdeceec752e55a24286a1cd62ae4
Disease	lymphangioleiomyomatosis (is_marker_for)	CPT1A STAT1 NOS3	1.67e-05	12	127	3	DOID:3319 (is_marker_for)
Disease	body surface area	PCSK1 PAPPA2 TICRR COL24A1 FBN1 FBN2 TNFSF13B MACF1 CTPS1 TASOR TSEN15 ECE2	2.28e-05	643	127	12	EFO_0022196
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2	5.50e-05	3	127	2	DOID:65 (implicated_via_orthology)
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	1.10e-04	4	127	2	DOID:0060249 (is_implicated_in)
Disease	Vesico-Ureteral Reflux	DSTYK ROBO2	1.10e-04	4	127	2	C0042580
Disease	Liver carcinoma	TICRR MED1 ME1 STAT1 DIPK2B PPP4R3C KMT2A BMPER CDC6	3.59e-04	507	127	9	C2239176
Disease	Behcet's disease (is_implicated_in)	PROZ NOS3 IL23R	5.01e-04	36	127	3	DOID:13241 (is_implicated_in)
Disease	Secondary Biliary Cholangitis	SLC4A2 NOS3 IL7R	7.91e-04	42	127	3	C0238065
Disease	Biliary cirrhosis	SLC4A2 NOS3 IL7R	7.91e-04	42	127	3	C0023892
Disease	Biliary Cirrhosis, Primary, 1	SLC4A2 NOS3 IL7R	7.91e-04	42	127	3	C4551595
Disease	Primary biliary cirrhosis	SLC4A2 NOS3 IL7R	1.10e-03	47	127	3	C0008312
Disease	lean body mass	PCSK1 VPS13C MST1R PLEKHA1 TASOR TSEN15 NOS3	1.31e-03	379	127	7	EFO_0004995
Disease	tumor necrosis factor ligand superfamily member 11 measurement	IGHV3-21 IGHV3-7	1.39e-03	13	127	2	EFO_0010617
Disease	Prostatic Neoplasms	DDR1 MYBBP1A ERP44 KAT6A MAP3K1 SLC4A2 KMT2A ROBO2 NOS3	1.42e-03	616	127	9	C0033578
Disease	Malignant neoplasm of prostate	DDR1 MYBBP1A ERP44 KAT6A MAP3K1 SLC4A2 KMT2A ROBO2 NOS3	1.42e-03	616	127	9	C0376358
Disease	pulse pressure measurement, social deprivation	FBN1 CTPS1	1.62e-03	14	127	2	EFO_0005763, EFO_0009696
Disease	Spastic Paraplegia, Hereditary	L1CAM ABCD1	1.62e-03	14	127	2	C0037773
Disease	birth weight	PAPPA2 NPEPL1 ME1 STAT1 PTPDC1 TNFSF13B PLEKHA1	1.75e-03	399	127	7	EFO_0004344
Disease	glycerate measurement	HMCN1 AGRN	1.86e-03	15	127	2	EFO_0021029
Disease	cortical surface area measurement	TICRR NCAPD3 PRSS12 KIF1B STAT1 MAP3K1 COL24A1 FBN1 FBN2 TBC1D22A DSTYK MACF1 ROBO2 PLXNA2	1.99e-03	1345	127	14	EFO_0010736
Disease	Rolandic epilepsy	KALRN PTPRM	2.12e-03	16	127	2	Orphanet_1945
Disease	neuroimaging measurement	PRSS12 KIF1B REV3L GTDC1 STAT1 MAP3K1 COL24A1 FBN2 DSTYK MACF1 ROBO2 PLXNA2	2.27e-03	1069	127	12	EFO_0004346
Disease	androstenedione measurement, estrone measurement	PTPRM BMPER	2.69e-03	18	127	2	EFO_0007970, EFO_0007972
Disease	body weight	PCSK1 PAPPA2 RASA2 VPS13C ACTR3B FBN2 TNFSF13B CDC16 PLEKHA1 KAT6B TSEN15 NOS3 PLXNA1	3.12e-03	1261	127	13	EFO_0004338
Disease	ascending aortic diameter	PCSK1 FBN1 FBN2 HMCN1	3.20e-03	140	127	4	EFO_0021787
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	PCSK1 CPT1A FBN1 NOS3	3.80e-03	147	127	4	DOID:9352 (biomarker_via_orthology)
Disease	breast cancer (is_implicated_in)	MAP3K1 UBR5 KAT6B NOS3	4.09e-03	150	127	4	DOID:1612 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QELGREIALPIEACV	BARGIN	291	Q6ZT62
EIGAQVCAEELEPAA	BHLHB9	141	Q6PI77
PENAEATVVLVGCVE	SLC4A2	511	P04920
ITIIQDGDITCPEDA	ADGRF3	421	Q8IZF5
LCPIVDVVLGLVNDQ	BPIFB4	331	P59827
ISDVVDEVIQNCPID	ACTR3B	296	Q9P1U1
DPNIIRLLGVCVQDD	DDR1	681	Q08345
ESNIEDPLIVTPDCQ	MASTL	601	Q96GX5
LQQTQIEEARAGPCE	AGRN	651	O00468
QDPIVVVNCLRSLEE	AP4B1	171	Q9Y6B7
DIPGECQEVIETSLN	CPT1A	521	P50416
DQLQELCIPQDLVGD	COMMD5	111	Q9GZQ3
PEEVTELVLDNCLCV	ANP32E	16	Q9BTT0
NLDIGAQLIVEECPS	ANKRA2	6	Q9H9E1
EVDFVDINVGCPIDL	DUS3L	386	Q96G46
SPVQDDIDSILVQCG	DIPK2B	376	Q9H7Y0
VATVPLENQCLEEIS	ASTN1	776	O14525
DPDAEVQGEICLSVQ	RASAL1	111	O95294
CTAGVPADIQIDIDE	RASA2	741	Q15283
EIILTACPQDLIQAE	NUP205	1291	Q92621
QLEPTCEIEVEEDGR	KAT6B	1171	Q8WYB5
EVQINNEEIFPTCVG	MOB3B	126	Q86TA1
QVVDVEQGIICENIP	ABCD1	466	P33897
RGLVEENPEVAVDCV	ACACB	2416	O00763
LLVSGQCEEEEPIQV	AP1G1	486	O43747
PNCVTNLEILLEDTV	PCDHGA4	131	Q9Y5G9
DIALVRLQGPEEQCA	PRSS12	726	P56730
QECLPVILDVGTENE	ME1	186	P48163
VLQEICDEVNLPLLT	NUDT22	186	Q9BRQ3
VAILEGVQCEVQLVE	IGHV3-7	11	P01780
EELCQIQESGSSLPE	FYCO1	1286	Q9BQS8
ECVSQAIDINEPIGN	GABPA	36	Q06546
QEESQAGIIPQLCEE	KIF1B	111	O60333
CLTGVEDQLQADVRP	ATP9B	736	O43861
EQIIVEVFEQCGEII	ENOX2	141	Q16206
VAILEGVQCEVQLVE	IGHV3-13	11	P01766
SCLQVERIEELGAQP	ECE2	226	P0DPD6
VAILEGVQCEVQLVE	IGHV3-48	11	P01763
PLITVDECLQALEEV	MOAP1	226	Q96BY2
LEGRVNVSEDCPQIL	PLXNA1	696	Q9UIW2
QEGRINISEDCPQLV	PLXNA2	691	O75051
NISEDCPQLVPTEEI	PLXNA2	696	O75051
GCLETKQDNLPDIEV	KRT222	261	Q8N1A0
LNLVSPLGCEVDVEE	NPEPL1	496	Q8NDH3
AEQLAQTGECDPEEI	KALRN	601	O60229
CEEGVTPLVELQNQI	MACF1	476	O94854
VEVEEGESVVLPCNP	L1CAM	146	P32004
EQEERLCEQEKLPGQ	GOLGA6L9	231	A6NEM1
QEERLCEQEKLPGQE	GOLGA6L10	316	A6NI86
DPDVNITNLEFEICG	IL7R	61	P16871
CIVNLQTIPVDVEEA	PTPDC1	691	A2A3K4
GCVDIKDLPVSEQQE	PSMD13	181	Q9UNM6
VAILEGVQCEVQLVE	IGHV3-21	11	A0A0B4J1V1
SQICEQVIIQDDGPE	POF1B	236	Q8WVV4
LLQEVDVVVAPCQGL	DSTYK	216	Q6XUX3
CAGPEEQELSLQEEV	IL20RA	411	Q9UHF4
EGCQDDPERQLAVLV	MYBBP1A	361	Q9BQG0
EEISVIVNNPLELTC	HMCN1	3536	Q96RW7
CPLEELEEPRGQQEV	ITGB7	91	P26010
VRGDPANVEITELCI	NOS3	261	P29474
VVLPDCELNTLDQIA	PPP4R3C	131	Q6ZMV5
QCPREEDIVEVQGSP	PRG3	91	Q9Y2Y8
GEDNICVPDLQLEVF	ITGA5	646	P08648
EPQCQERELEISVGK	KAT6A	801	Q92794
NICDDEGLNPIVSEE	PAPPA2	531	Q9BXP8
PESVDGLQENLDVVV	CDC16	221	Q13042
ISEVVDEVIQNCPID	ACTR3	296	P61158
RVQEEPELVFTLGDC	FKBP8	136	Q14318
SVAKCENEGEVLQIP	BMPER	46	Q8N8U9
EPCVLRQCQEGVVTE	BMPER	126	Q8N8U9
VKGENLEAVVCEEPQ	CD99L2	226	Q8TCZ2
LPEVTEEDQGRICVV	CTDSP2	91	O14595
SNRCIQEVGLQEDPL	DBX2	251	Q6ZNG2
TVILEDIDECQELPG	FBN1	1601	P35555
PDEFVSCLGIVNEEL	IL23R	591	Q5VWK5
IAQEICQEEVSRPAG	CDC6	246	Q99741
AIVDCIISIVEENPE	COPG2	416	Q9UBF2
CVPLVREITFENGEE	ERP44	241	Q9BS26
EAIPDTLQVLECGEE	MARF1	1311	Q9Y4F3
VRQVQGPVLVEDTCL	ITPA	61	Q9BY32
EEQCDLPKISQLDGV	KMT2A	2706	Q03164
GSILQLCEEIAGEIE	ESCO1	301	Q5FWF5
PNPITIILEDIDECQ	FBN2	1641	P35556
QLVDLLQEELGDCVV	GTDC1	16	Q4AE62
SQLVDEVVCALQPVI	OLAH	76	Q9NV23
DVEIQATDICDPNPI	CFAP47	1841	Q6ZTR5
VEGCLEQRLEENLPT	C2CD5	446	Q86YS7
IEPLNEVQSCEGLRD	DPY19L2P2	36	Q6ZN68
EVQLDPAGQLCDVKV	MED1	111	Q15648
QELIVQTDEDLPGAV	PTPRM	471	P28827
ADPVEAVLQLQDCSI	NUMA1	21	Q14980
ENGEDIIIIQQDTPE	MAP3K1	1211	Q13233
ETQLCQPGLVIDLET	STAT1	436	P42224
IIIPCEFCGVQLEEE	TRAFD1	366	O14545
NCATEIPQIVEISIE	SOCS5	81	O75159
DSDIVIPQDVTEDCG	RIF1	1126	Q5UIP0
IPEGLEQADVEAVLQ	PNMA8B	26	Q9ULN7
LGNIQGEELLVSECE	SMG1	1886	Q96Q15
IPVDEDGLEPQVCVI	CTPS1	131	P17812
EDVNLLVTCREEGNP	SLC5A3	601	P53794
LVEGEECGQVLNVTV	PROZ	321	P22891
DDVLTGQVEEQCVPA	TASOR	991	Q9UK61
ETPAEEQELLTQVCG	NCAPD3	811	P42695
LDTLVAVIECQQPEA	ATP11B	201	Q9Y2G3
EGIVCQLDIIPSAEA	COL24A1	216	Q17RW2
SEDGENLEILCPVQD	RNF17	716	Q9BXT8
EGENICFEVLDAVLP	TOP3B	121	O95985
NKEEPQICVIELGGT	CTPS2	136	Q9NRF8
TELGDCEIVLLVNGE	ZBTB11	356	O95625
CEIVLLVNGELPEAE	ZBTB11	361	O95625
RTPILEDFELEGVCQ	TICRR	1731	Q7Z2Z1
EGVEPQSTCELEVDA	REV3L	226	O60673
VCDLLLEESNVQPVS	PPP6C	31	O00743
IIDLPQNEDIEAICL	WDHD1	526	O75717
PENCQEVVALVEGVT	ZNF274	226	Q96GC6
LLCDLPIQVTLEEVN	SNRNP25	16	Q9BV90
LIEENCGVVVESIQV	VPS13C	2271	Q709C8
DVVVAAGEPAILECQ	ROBO2	141	Q9HCK4
VDVSGVPAEVLCNIE	TBC1D22A	346	Q8WUA7
LQRCPEVDLLTQVDG	SLF1	861	Q9BQI6
ECVPILRELAGVEQA	TTC23	226	Q5W5X9
ACVDELLELVVQAVP	PLIN5	356	Q00G26
GIPANLIQQLDVCVE	TARBP1	1571	Q13395
DVCVEIPQQGIIRSL	TARBP1	1581	Q13395
ACLVLVLNTQPAEEE	ERCC4	56	Q92889
QCPENGEEAVTLVED	ZSCAN29	81	Q8IWY8
IITPTQKEEVNECGE	PLEKHA1	151	Q9HB21
QGPEETVTQDCLQLI	TNFSF13B	136	Q9Y275
EEFECELEPLGTQAV	MST1R	636	Q04912
QTEPLCAIQDAEGAI	XIRP1	236	Q702N8
ELQLICLVGTEIEGE	TSEN15	86	Q8WW01
VVGLESQCRPQELDQ	TMEM139	96	Q8IV31
VIEDEQLVLGASQEP	TWF2	31	Q6IBS0
AEQLAQTGECDPEEI	TRIO	631	O75962
AVEELCNVAESLIVP	UBR5	1471	O95071
PVLGENCRLEVIIEE	SLC8A2	651	Q9UPR5
ANGEVIIEIPTRACE	PCSK1	481	P29120
IIEIPTRACEGQENA	PCSK1	486	P29120