Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 TRPC6 PKD2L1 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4	1.82e-08	151	186	12	GO:0015085
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 MRS2 SLC39A9 TRPC6 TMEM175 PKD2L1 SLC30A4 SLC30A5 KCNU1 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 CHP1	7.66e-08	465	186	19	GO:0046873
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 MRS2 SLC39A9 PIEZO1 TRPC6 TMEM175 PKD2L1 OCA2 SLC30A4 BSND SLC26A8 SLC30A5 KCNU1 CLCN6 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 UNC80 CHP1	9.85e-08	793	186	25	GO:0015075
GeneOntologyMolecularFunction	transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SLC25A42 MRS2 SLC39A9 PIEZO1 GRAMD1A TRPC6 TMEM175 SLC35E1 PKD2L1 OCA2 ATG2A SLC30A4 ABCB4 BSND SLC26A8 SLC30A5 KCNU1 CLCN6 TRPM3 ATP2C2 TRPV2 LRP5 CACNA1G OSCP1 SLC25A19 CNGA4 UNC80 CHP1	1.04e-07	1289	186	33	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SLC25A42 MRS2 SLC39A9 PIEZO1 TRPC6 TMEM175 SLC35E1 PKD2L1 OCA2 SLC30A4 ABCB4 BSND SLC26A8 SLC30A5 KCNU1 CLCN6 TRPM3 ATP2C2 TRPV2 LRP5 CACNA1G OSCP1 SLC25A19 CNGA4 UNC80 CHP1	1.53e-07	1180	186	31	GO:0022857
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1A GPM6A CACNA1S CACNA2D1 PIEZO1 TRPC6 TMEM175 PKD2L1 OCA2 BSND SLC26A8 KCNU1 CLCN6 TRPM3 TRPV2 CACNA1G CNGA4 UNC80	3.14e-07	459	186	18	GO:0005216
GeneOntologyMolecularFunction	calcium channel activity	CACNA1A GPM6A CACNA1S CACNA2D1 TRPC6 PKD2L1 TRPM3 TRPV2 CACNA1G CNGA4	3.64e-07	129	186	10	GO:0005262
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 MRS2 SLC39A9 TRPC6 TMEM175 PKD2L1 OCA2 SLC30A4 BSND SLC26A8 SLC30A5 KCNU1 CLCN6 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 CHP1	6.52e-07	758	186	23	GO:0015318
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 MRS2 SLC39A9 PIEZO1 TRPC6 TMEM175 PKD2L1 SLC30A4 SLC30A5 KCNU1 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 UNC80 CHP1	1.08e-06	664	186	21	GO:0008324
GeneOntologyMolecularFunction	channel activity	CACNA1A GPM6A CACNA1S CACNA2D1 PIEZO1 TRPC6 TMEM175 PKD2L1 OCA2 BSND SLC26A8 KCNU1 CLCN6 TRPM3 TRPV2 CACNA1G CNGA4 UNC80	2.16e-06	525	186	18	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 PIEZO1 TRPC6 TMEM175 PKD2L1 OCA2 BSND SLC26A8 KCNU1 CLCN6 TRPM3 TRPV2 CACNA1G CNGA4 UNC80	2.22e-06	526	186	18	GO:0022803
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1A GPM6A CACNA1S CACNA2D1 PIEZO1 TRPC6 TMEM175 PKD2L1 KCNU1 TRPM3 TRPV2 CACNA1G CNGA4 UNC80	4.31e-06	343	186	14	GO:0005261
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 MRS2 SLC39A9 TRPC6 TMEM175 PKD2L1 SLC30A4 SLC30A5 KCNU1 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 CHP1	6.68e-06	627	186	19	GO:0022890
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR51A4 OR51A2 SPHK2 OR4K17 GPR31 SLC39A9 GPR85 OR6C74 PKD2L1 OR13H1 ADGRG1 GPR63 OR2T34 ACVR1C TAAR6 OR11H6 TLR10 TGFBR1 OR52I2 OR4C15 NRXN2 EGFR IL1RAPL2 LRP5 TAAR9 OR4K15 GNRHR PLXNB1 HCRTR2 EPHA8	8.02e-06	1353	186	30	GO:0004888
GeneOntologyMolecularFunction	zinc efflux transmembrane transporter activity	SLC39A9 SLC30A5	8.63e-05	2	186	2	GO:0022883
GeneOntologyMolecularFunction	monoatomic cation efflux transmembrane transporter activity	SLC39A9 SLC30A5	8.63e-05	2	186	2	GO:0046583
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3CB PIK3CD ATM	1.24e-04	11	186	3	GO:0016303
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR51A4 OR51A2 SPHK2 OR4K17 GPR31 SLC39A9 GPR85 OR6C74 OR13H1 ADGRG1 GPR63 OR2T34 TAAR6 OR11H6 OR52I2 OR4C15 TAAR9 OR4K15 GNRHR HCRTR2	2.29e-04	884	186	20	GO:0004930
GeneOntologyMolecularFunction	KDEL sequence binding	KDELR2 KDELR1	2.57e-04	3	186	2	GO:0005046
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1A CACNA1S CACNA1G	2.68e-04	14	186	3	GO:0008331
GeneOntologyMolecularFunction	antiporter activity	SLC35E1 SLC30A4 SLC26A8 SLC30A5 CLCN6 SLC25A19 CHP1	3.16e-04	138	186	7	GO:0015297
GeneOntologyMolecularFunction	lipid kinase activity	SPHK2 PIK3CB PIK3CD ATM	5.64e-04	41	186	4	GO:0001727
GeneOntologyMolecularFunction	transition metal ion transmembrane transporter activity	SLC39A9 SLC30A4 SLC30A5 ATP2C2	7.40e-04	44	186	4	GO:0046915
GeneOntologyMolecularFunction	histone H2AX kinase activity	BAZ1B ATM	8.47e-04	5	186	2	GO:0141003
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA2D1 CACNA1G	8.47e-04	5	186	2	GO:0086007
GeneOntologyMolecularFunction	activin receptor activity, type I	ACVR1C TGFBR1	8.47e-04	5	186	2	GO:0016361
GeneOntologyMolecularFunction	ER retention sequence binding	KDELR2 KDELR1	8.47e-04	5	186	2	GO:0046923
GeneOntologyMolecularFunction	histone H3K9me/H3K9me2 demethylase activity	KDM3B PHF8	8.47e-04	5	186	2	GO:0140683
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1A CACNA1S CACNA2D1 CACNA1G	8.76e-04	46	186	4	GO:0005245
GeneOntologyMolecularFunction	glucosyltransferase activity	ALG8 POGLUT2 PLOD1	1.07e-03	22	186	3	GO:0046527
GeneOntologyMolecularFunction	zinc ion transmembrane transporter activity	SLC39A9 SLC30A4 SLC30A5	1.39e-03	24	186	3	GO:0005385
GeneOntologyMolecularFunction	1-phosphatidylinositol-4-phosphate 3-kinase activity	PIK3CB PIK3CD	1.76e-03	7	186	2	GO:0035005
GeneOntologyMolecularFunction	N-acylsphingosine amidohydrolase activity	ACER2 ACER1	1.76e-03	7	186	2	GO:0017040
GeneOntologyMolecularFunction	1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	PIK3CB PIK3CD	1.76e-03	7	186	2	GO:0046934
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIK3CB PIK3CD ATM	1.77e-03	26	186	3	GO:0052742
GeneOntologyMolecularFunction	trace-amine receptor activity	TAAR6 TAAR9	2.33e-03	8	186	2	GO:0001594
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SPHK2 NPR2 PDK3 BAZ1B ACVR1C CHKA MAP3K5 TGFBR1 EGFR PIK3CB PIK3CD SIK2 ATM CDK6 EPHA8	2.69e-03	709	186	15	GO:0016773
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SPHK2 MRS2 SLC39A9 PIEZO1 TRPC6 TMEM175 PKD2L1 OCA2 RNASEK TLR9 SLC30A4 BSND SLC26A8 SLC30A5 KCNU1 CLCN6 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 UNC80 PML CHP1	2.29e-07	1115	185	29	GO:0034220
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SPHK2 MRS2 SLC39A9 TRPC6 TMEM175 PKD2L1 OCA2 RNASEK TLR9 SLC30A4 BSND SLC26A8 SLC30A5 KCNU1 CLCN6 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 PML CHP1	4.23e-07	1017	185	27	GO:0098660
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SPHK2 MRS2 SLC39A9 PIEZO1 TRPC6 TMEM175 PKD2L1 RNASEK TLR9 SLC30A4 SLC30A5 KCNU1 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 UNC80 PML CHP1	1.20e-06	942	185	25	GO:0098655
GeneOntologyBiologicalProcess	monoatomic ion transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SPHK2 MRS2 SLC39A9 PIEZO1 TRPC6 TMEM175 PKD2L1 SPG11 OCA2 RNASEK TLR9 SLC30A4 BSND SLC26A8 SLC30A5 KCNU1 EGF CLCN6 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 UNC80 PML CHP1	1.78e-06	1374	185	31	GO:0006811
GeneOntologyBiologicalProcess	calcium ion import	CACNA1A CACNA1S CACNA2D1 SPHK2 EGF ATP2C2 TRPV2 CACNA1G	2.85e-06	98	185	8	GO:0070509
GeneOntologyBiologicalProcess	carbohydrate derivative biosynthetic process	ACER2 SPHK2 NPR2 SLC25A42 PDK3 DAD1 TNIP1 ADCY7 LIPC SLC30A5 EGF ACSBG1 GALNT11 ALG8 CHPF2 DSEL POGLUT2 PLOD1 MGAT5B PID1 CHP1	3.02e-06	736	185	21	GO:1901137
GeneOntologyBiologicalProcess	calcium ion transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SPHK2 TRPC6 PKD2L1 SPG11 TLR9 EGF TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 PML	3.61e-06	509	185	17	GO:0006816
GeneOntologyBiologicalProcess	monoatomic cation transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SPHK2 MRS2 SLC39A9 PIEZO1 TRPC6 TMEM175 PKD2L1 SPG11 RNASEK TLR9 SLC30A4 SLC30A5 KCNU1 EGF TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 UNC80 PML CHP1	4.89e-06	1157	185	27	GO:0006812
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SPHK2 MRS2 SLC39A9 TRPC6 TMEM175 PKD2L1 RNASEK TLR9 SLC30A4 SLC30A5 KCNU1 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 PML CHP1	9.15e-06	922	185	23	GO:0098662
GeneOntologyBiologicalProcess	metal ion transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 SPHK2 MRS2 SLC39A9 TRPC6 TMEM175 PKD2L1 SPG11 TLR9 SLC30A4 SLC30A5 KCNU1 EGF TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 PML CHP1	1.09e-05	1000	185	24	GO:0030001
GeneOntologyBiologicalProcess	calcium ion transmembrane transport	CACNA1A GPM6A CACNA1S CACNA2D1 ATP13A4 TRPC6 PKD2L1 TLR9 TRPM3 ATP2C2 TRPV2 CACNA1G CNGA4 PML	1.28e-05	392	185	14	GO:0070588
GeneOntologyBiologicalProcess	phosphatidylinositol-3-phosphate biosynthetic process	FIG4 PIK3CB PIK3CD ATM	4.04e-05	22	185	4	GO:0036092
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	CACNA1A CACNA1S CACNA2D1 TRPV2 CACNA1G	6.89e-05	48	185	5	GO:0098703
GeneOntologyBiologicalProcess	calcium ion import into cytosol	CACNA1A CACNA1S CACNA2D1 TRPV2 CACNA1G	6.89e-05	48	185	5	GO:1902656
GeneOntologyBiologicalProcess	glycoprotein biosynthetic process	ACER2 DAD1 TNIP1 LIPC GALNT11 ALG8 CHPF2 DSEL POGLUT2 PLOD1 MGAT5B CHP1	9.62e-05	357	185	12	GO:0009101
GeneOntologyBiologicalProcess	carbohydrate derivative metabolic process	ACER2 SPHK2 NPR2 SLC25A42 PDK3 DAD1 TNIP1 ADCY7 FASN LIPC SLC30A5 EGF PEMT ACSBG1 GALNT11 SIK2 ALG8 CHPF2 DSEL POGLUT2 PLOD1 MGAT5B MTCH2 PID1 CHP1	1.04e-04	1226	185	25	GO:1901135
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	CACNA1A CACNA1S ATP13A4 SLC39A9 TRPC6 TMEM175 OCA2 RNASEK BSND SLC30A5 PIK3CB TMEM178A ATP2C2 HCRTR2 PML CHP1	1.31e-04	611	185	16	GO:0030003
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	CACNA1A CACNA1S ATP13A4 SLC39A9 TRPC6 TMEM175 OCA2 RNASEK BSND SLC30A5 PIK3CB TMEM178A ATP2C2 HCRTR2 PML CHP1	1.60e-04	622	185	16	GO:0006873
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	CACNA1A CACNA1S ATP13A4 SLC39A9 TRPC6 TMEM175 OCA2 RNASEK BSND SLC30A5 PIK3CB TMEM178A ATP2C2 UNC80 HCRTR2 PML CHP1	2.15e-04	705	185	17	GO:0055080
GeneOntologyBiologicalProcess	organophosphate biosynthetic process	SPHK2 NPR2 SLC25A42 PDK3 CHKA ADCY7 SLC30A5 PEMT ACSBG1 FIG4 PIK3CB PIK3CD ATM SLC25A19 PID1 CHP1	2.37e-04	644	185	16	GO:0090407
GeneOntologyBiologicalProcess	organophosphate metabolic process	SPHK2 NPR2 SLC25A42 PDK3 NCF1 PLCD4 CHKA ADCY7 FASN LIPC SLC30A5 PEMT ACSBG1 FIG4 PIK3CB PIK3CD SIK2 ATM SLC25A19 NCF1B MTCH2 PID1 CHP1	2.40e-04	1142	185	23	GO:0019637
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	CACNA1A CACNA1S ATP13A4 SLC39A9 TRPC6 TMEM175 OCA2 RNASEK BSND SLC30A5 PIK3CB TMEM178A ATP2C2 UNC80 HCRTR2 PML CHP1	2.62e-04	717	185	17	GO:0050801
GeneOntologyBiologicalProcess	sphingosine biosynthetic process	ACER2 SPHK2 ACER1	2.98e-04	15	185	3	GO:0046512
GeneOntologyBiologicalProcess	sphingoid biosynthetic process	ACER2 SPHK2 ACER1	2.98e-04	15	185	3	GO:0046520
GeneOntologyBiologicalProcess	histone mRNA catabolic process	EXOSC10 TENT4B ATM	2.98e-04	15	185	3	GO:0071044
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	CACNA1A CACNA1S ATP13A4 ATG7 SLC39A9 NCF1 TRPC6 TMEM175 OCA2 RNASEK BSND SLC30A5 PIK3CB TMEM178A ATP2C2 LRP5 HCRTR2 PML CHP1	3.02e-04	866	185	19	GO:0055082
GeneOntologyBiologicalProcess	chemical homeostasis	CACNA1A CACNA1S ATP13A4 TENT4B ATG7 SLC39A9 NCF1 TRPC6 TMEM175 OCA2 RNASEK ABCB4 BSND LIPC SLC30A5 PIK3CB TMEM178A ATP2C2 LRP5 MTCH2 UNC80 HCRTR2 PML CHP1	3.47e-04	1249	185	24	GO:0048878
GeneOntologyCellularComponent	calcium channel complex	CACNA1A CACNA1S CACNA2D1 PKD2L1 CACNA1G TMEM262	4.75e-05	73	186	6	GO:0034704
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1A CACNA1S CACNA2D1 CACNA1G TMEM262	5.39e-05	46	186	5	GO:0005891
GeneOntologyCellularComponent	cation channel complex	CACNA1A CACNA1S CACNA2D1 TRPC6 PKD2L1 CACNA1G TMEM262 CNGA4 UNC80	2.65e-04	235	186	9	GO:0034703
MousePheno	abnormal Purkinje cell axon morphology	CACNA1A SACS ATM CHP1	8.23e-06	13	149	4	MP:0014329
Domain	Ion_trans_dom	CACNA1A CACNA1S TRPC6 KCNU1 TRPM3 TRPV2 CACNA1G CNGA4	1.72e-05	114	184	8	IPR005821
Domain	Ion_trans	CACNA1A CACNA1S TRPC6 KCNU1 TRPM3 TRPV2 CACNA1G CNGA4	1.72e-05	114	184	8	PF00520
Domain	VDCCAlpha1	CACNA1A CACNA1S CACNA1G	1.07e-04	10	184	3	IPR002077
Domain	ER_ret_rcpt	KDELR2 KDELR1	2.88e-04	3	184	2	IPR000133
Domain	ER_lumen_recept	KDELR2 KDELR1	2.88e-04	3	184	2	PF00810
Domain	ER_LUMEN_RECEPTOR_1	KDELR2 KDELR1	2.88e-04	3	184	2	PS00951
Domain	ER_LUMEN_RECEPTOR_2	KDELR2 KDELR1	2.88e-04	3	184	2	PS00952
Domain	Ceramidase	ACER2 ACER1	2.88e-04	3	184	2	PF05875
Domain	Ceramidase	ACER2 ACER1	2.88e-04	3	184	2	IPR008901
Domain	PI3K_p85B	PIK3CB PIK3CD	2.88e-04	3	184	2	PF02192
Domain	PI3K_p85B	PIK3CB PIK3CD	2.88e-04	3	184	2	SM00143
Domain	GPCR_Rhodpsn_7TM	OR51A4 OR51A2 OR4K17 GPR31 GPR85 OR6C74 OR13H1 GPR63 OR2T34 TAAR6 OR11H6 OR52I2 OR4C15 TAAR9 OR4K15 GNRHR HCRTR2	3.50e-04	670	184	17	IPR017452
Domain	PI3/4_kinase_CS	PIK3CB PIK3CD ATM	3.92e-04	15	184	3	IPR018936
Domain	7tm_1	OR51A4 OR51A2 OR4K17 GPR31 GPR85 OR6C74 OR13H1 GPR63 OR2T34 TAAR6 OR11H6 OR52I2 OR4C15 TAAR9 OR4K15 GNRHR HCRTR2	3.94e-04	677	184	17	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR51A4 OR51A2 OR4K17 GPR31 GPR85 OR6C74 OR13H1 GPR63 OR2T34 TAAR6 OR11H6 OR52I2 OR4C15 TAAR9 OR4K15 GNRHR HCRTR2	4.50e-04	685	184	17	PS00237
Domain	-	PIK3CB PIK3CD ATM	4.79e-04	16	184	3	1.10.1070.11
Domain	PI3Kc	PIK3CB PIK3CD ATM	4.79e-04	16	184	3	SM00146
Domain	G_PROTEIN_RECEP_F1_2	OR51A4 OR51A2 OR4K17 GPR31 GPR85 OR6C74 OR13H1 GPR63 OR2T34 TAAR6 OR11H6 OR52I2 OR4C15 TAAR9 OR4K15 GNRHR HCRTR2	4.97e-04	691	184	17	PS50262
Domain	GPCR_Rhodpsn	OR51A4 OR51A2 OR4K17 GPR31 GPR85 OR6C74 OR13H1 GPR63 OR2T34 TAAR6 OR11H6 OR52I2 OR4C15 TAAR9 OR4K15 GNRHR HCRTR2	5.05e-04	692	184	17	IPR000276
Domain	PI3K_ABD	PIK3CB PIK3CD	5.72e-04	4	184	2	PS51544
Domain	PI3K_adapt-bd_dom	PIK3CB PIK3CD	5.72e-04	4	184	2	IPR003113
Domain	PI3_PI4_kinase	PIK3CB PIK3CD ATM	6.88e-04	18	184	3	PF00454
Domain	PI3_4_KINASE_1	PIK3CB PIK3CD ATM	6.88e-04	18	184	3	PS00915
Domain	PI3_4_KINASE_2	PIK3CB PIK3CD ATM	6.88e-04	18	184	3	PS00916
Domain	PI3/4_kinase_cat_dom	PIK3CB PIK3CD ATM	6.88e-04	18	184	3	IPR000403
Domain	PI3_4_KINASE_3	PIK3CB PIK3CD ATM	6.88e-04	18	184	3	PS50290
Domain	7TM_GPCR_Srsx	OR51A4 OR51A2 OR2T34 TAAR6 TAAR9 HCRTR2	8.50e-04	112	184	6	SM01381
Domain	TIR	TLR9 TLR10 IL1RAPL2	1.10e-03	21	184	3	SM00255
Domain	TIR	TLR9 TLR10 IL1RAPL2	1.26e-03	22	184	3	PF01582
Domain	-	TLR9 TLR10 IL1RAPL2	1.44e-03	23	184	3	3.40.50.10140
Domain	TIR	TLR9 TLR10 IL1RAPL2	1.63e-03	24	184	3	PS50104
Domain	-	ACAP1 APBB1 PLCD4 PREX2 PTPN4 PTPN14 CADPS APPL1 PID1 FGD3 PHLPP2	1.76e-03	391	184	11	2.30.29.30
Domain	TIR_dom	TLR9 TLR10 IL1RAPL2	1.84e-03	25	184	3	IPR000157
Domain	PI3K_Ras-bd_dom	PIK3CB PIK3CD	1.96e-03	7	184	2	IPR000341
Domain	TAAR_fam	TAAR6 TAAR9	1.96e-03	7	184	2	IPR009132
Domain	GS_dom	ACVR1C TGFBR1	1.96e-03	7	184	2	IPR003605
Domain	GS	ACVR1C TGFBR1	1.96e-03	7	184	2	PS51256
Domain	Ca_chan_IQ	CACNA1A CACNA1S	1.96e-03	7	184	2	SM01062
Domain	TGF_beta_GS	ACVR1C TGFBR1	1.96e-03	7	184	2	PF08515
Domain	Ca_chan_IQ	CACNA1A CACNA1S	1.96e-03	7	184	2	PF08763
Domain	PI3K_rbd	PIK3CB PIK3CD	1.96e-03	7	184	2	SM00144
Domain	GS	ACVR1C TGFBR1	1.96e-03	7	184	2	SM00467
Domain	VDCC_a1su_IQ	CACNA1A CACNA1S	1.96e-03	7	184	2	IPR014873
Domain	GPHH	CACNA1A CACNA1S	1.96e-03	7	184	2	PF16905
Domain	PI3K_rbd	PIK3CB PIK3CD	1.96e-03	7	184	2	PF00794
Domain	GPHH_dom	CACNA1A CACNA1S	1.96e-03	7	184	2	IPR031649
Domain	PI3K_RBD	PIK3CB PIK3CD	1.96e-03	7	184	2	PS51546
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	EGF EGFR PIK3CB PIK3CD	6.89e-07	8	143	4	M47498
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY	EGF EGFR PIK3CB PIK3CD	1.23e-06	9	143	4	M47392
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	EGF EGFR PIK3CB PIK3CD	4.72e-06	12	143	4	M47393
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY	EGF EGFR PIK3CB PIK3CD	9.39e-06	14	143	4	M47536
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY	EGF EGFR PIK3CB PIK3CD	1.27e-05	15	143	4	M47389
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY	EGFR PIK3CB PIK3CD	5.51e-05	8	143	3	M47394
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY	EGFR PIK3CB PIK3CD	5.51e-05	8	143	3	M47395
Pathway	KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	EGFR PIK3CB PIK3CD	5.51e-05	8	143	3	M47482
Pathway	KEGG_PANCREATIC_CANCER	TGFBR1 EGF EGFR PIK3CB PIK3CD CDK6	7.54e-05	70	143	6	M9726
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY	EGFR PIK3CB PIK3CD	8.21e-05	9	143	3	M47481
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1A CACNA1S CACNA2D1 CACNA1G	1.09e-04	25	143	4	M47948
Pathway	KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	EGFR PIK3CB PIK3CD	1.16e-04	10	143	3	M47400
Pathway	KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY	EGFR PIK3CB PIK3CD	1.59e-04	11	143	3	M47499
Pathway	KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY	EGFR PIK3CB PIK3CD	1.59e-04	11	143	3	M47501
Pathway	KEGG_NON_SMALL_CELL_LUNG_CANCER	EGF EGFR PIK3CB PIK3CD CDK6	2.12e-04	54	143	5	M19818
Pathway	WP_PANCREATIC_ADENOCARCINOMA_PATHWAY	TGFBR1 EGF EGFR PIK3CB PIK3CD CDK6	2.86e-04	89	143	6	M39732
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	CACNA1A CACNA1S CACNA2D1 MAP3K5 TGFBR1 EGF EGFR GNA12 CACNA1G CHP1	3.94e-04	267	143	10	M10792
Pathway	PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY	EGF EGFR PIK3CB PIK3CD	4.16e-04	35	143	4	M127
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP13A4 TRPC6 BSND CLCN6 TRPM3 ATP2C2 TRPV2 UNC80	4.28e-04	176	143	8	MM15718
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	CACNA1A CACNA1S SPHK2 PLCD4 ADCY7 EGFR CACNA1G CHP1	4.61e-04	178	143	8	M2890
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPC6 BSND CLCN6 TRPM3 TRPV2 UNC80	5.07e-04	99	143	6	MM14910
Pathway	KEGG_GLIOMA	EGF EGFR PIK3CB PIK3CD CDK6	5.07e-04	65	143	5	M1835
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP13A4 TRPC6 BSND CLCN6 TRPM3 ATP2C2 TRPV2 UNC80	5.54e-04	183	143	8	M997
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPC6 BSND CLCN6 TRPM3 TRPV2 UNC80	7.28e-04	106	143	6	M27200
Pathway	KEGG_MELANOMA	EGF EGFR PIK3CB PIK3CD CDK6	7.62e-04	71	143	5	M15798
Pathway	PID_ERBB1_INTERNALIZATION_PATHWAY	EGF EGFR PIK3CB PIK3CD	7.68e-04	41	143	4	M214
Pathway	WP_NONSMALL_CELL_LUNG_CANCER	EGF EGFR PIK3CB PIK3CD CDK6	8.12e-04	72	143	5	M39738
Pathway	PID_TCPTP_PATHWAY	EGF EGFR PIK3CB PIK3CD	8.42e-04	42	143	4	M91
Pathway	WP_MAPK_SIGNALING	CACNA1A CACNA1S CACNA2D1 MAP3K5 TGFBR1 EGF EGFR GNA12 CACNA1G	9.09e-04	246	143	9	M39597
Pathway	WP_BREAST_CANCER_PATHWAY	MRE11 EGF EGFR PIK3CD LRP5 ATM CDK6	9.80e-04	154	143	7	M39739
Pathway	KEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_PI3K_SIGNALING_PATHWAY	PIK3CB PIK3CD	1.00e-03	5	143	2	M49020
Pathway	BIOCARTA_ERBB3_PATHWAY	EGF EGFR	1.00e-03	5	143	2	M22018
Pathway	KEGG_MEDICUS_PATHOGEN_EBV_LMP2A_TO_PI3K_SIGNALING_PATHWAY	PIK3CB PIK3CD	1.00e-03	5	143	2	M48997
Pathway	REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	EGF EGFR PIK3CB PIK3CD PHLPP2 KLB	1.02e-03	113	143	6	MM14783
Pathway	REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS	ADCY7 PREX2 EGF EGFR PIK3CB PIK3CD PHLPP2 PML KLB	1.08e-03	252	143	9	MM15585
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR51A4 OR51A2 OR4K17 RTP2 OR6C74 OR13H1 OR2T34 OR11H6 OR52I2 OR4C15 OR4K15 CNGA4	1.11e-03	417	143	12	M4072
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NRM CACNA2D1 MATN2 PIEZO1 GRAMD1A SLC35E1 DAD1 LAMA4 ADGRG1 RNF213 CSDE1 TGFBR1 EGFR FANCI RRP12 KDELR1 LRP5 CHPF2 ATM DSEL POGLUT2 PLOD1 MTCH2 PLXNB1 CHP1	8.96e-09	1201	188	25	35696571
Pubmed	Epidermal growth factor receptor signaling-dependent calcium elevation in cumulus cells is required for NPR2 inhibition and meiotic resumption in mouse oocytes.	NPR2 EGF EGFR	1.55e-07	3	188	3	23787120
Pubmed	Expression of nucleostemin, epidermal growth factor and epidermal growth factor receptor in human esophageal squamous cell carcinoma tissues.	EGF EGFR GNL3	1.55e-07	3	188	3	19823871
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	KDM3B TNIP1 PHF8 CLCN6 NRXN2 CADPS SIK2 APPL1 CACNA1G UNC80	4.59e-07	225	188	10	12168954
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EXOSC10 MRS2 PDK3 PIEZO1 GRAMD1A UBR4 APBB1 BAZ1B TNIP1 SPG11 ARFIP1 KIAA0753 TUBGCP6 UBE4A GUF1 PTPN14 EGFR SACS RRP12 SIK2 ATM PLOD1 ANKRD52 GNL3 PML	5.21e-07	1487	188	25	33957083
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	KDELR2 MRE11 PDLIM7 SLC35E1 APBB1 ARFIP1 CSDE1 UBE4A FASN SLC30A5 KDELR1 APPL1 MTCH2	1.16e-06	449	188	13	31732153
Pubmed	Ncf1 provides a reactive oxygen species-independent negative feedback regulation of TLR9-induced IL-12p70 in murine dendritic cells.	NCF1 TLR9 NCF1B	1.54e-06	5	188	3	19299716
Pubmed	Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae.	NCF1 PIK3CB PIK3CD NCF1B	1.86e-06	17	188	4	21257963
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	SPHK2 NPR2 SLC39A9 MAP3K5 SLC30A5 EGFR PIK3CB PIK3CD ATM PLOD1	2.90e-06	276	188	10	28319085
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MRE11 ZSWIM8 EXOSC10 UBR4 BAZ1B FRYL RBM39 CSDE1 FASN FANCI RRP12 ATM PLOD1 ANKRD52 GNL3	3.04e-06	653	188	15	22586326
Pubmed	Augmented EGF receptor tyrosine kinase activity impairs vascular function by NADPH oxidase-dependent mechanism in type 2 diabetic mouse.	NCF1 EGFR NCF1B	3.07e-06	6	188	3	26036345
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	COL27A1 GRAMD1A RNF213 TNIP1 ARHGAP39 MON1B KIAA0753 UBE4A TRPM3 SACS FIG4 APPL1 UNC80	3.24e-06	493	188	13	15368895
Pubmed	Inhibition of hsp90 compromises the DNA damage response to radiation.	MRE11 EGFR ATM	5.35e-06	7	188	3	16982765
Pubmed	Polymorphisms located in the region containing BHMT and BHMT2 genes as maternal protective factors for orofacial clefts.	CHKA PEMT BHMT2	5.35e-06	7	188	3	20662904
Pubmed	The DNA sequence of human chromosome 7.	KDELR2 CACNA2D1 NCF1 GPR85 BAZ1B ABCB4 EGFR ZNF277 GALNT11 GNA12 NCF1B CDK6	5.68e-06	441	188	12	12853948
Pubmed	Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access.	EGFR ATM PML	8.53e-06	8	188	3	21704408
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPHK2 KMT2B PCNX3 PIEZO1 UBR4 KDM3B FRYL ATG2A REV3L ADCY7 NBPF1 MAP3K5 TBC1D16 FASN PIK3CD FANCI RRP12 LRP5 GNA12	9.75e-06	1105	188	19	35748872
Pubmed	Genomic analysis of mouse retinal development.	ZSWIM8 COL16A1 KMT2B PCNX3 PDK3 KDM3B ADGRG1 FRYL RNASEK CHKA RBM39 COQ10A NRXN2 TRPM3 CADPS KDELR1 SLC25A19 PHLPP2	9.95e-06	1006	188	18	15226823
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MRE11 EXOSC10 KMT2B PDLIM7 APBB1 KDM3B BAZ1B TNIP1 PHF8 CSDE1 YEATS2 FASN PTPN14	1.03e-05	549	188	13	38280479
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CACNA1A ZSWIM8 CACNA2D1 EXOSC10 UBR4 RBM39 PREX2 MAP3K5 TUBGCP6 CADPS TRMT1L FBXW11	1.20e-05	475	188	12	31040226
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1A CACNA1S CACNA1G	1.27e-05	9	188	3	16382099
Pubmed	An introduction to TRP channels.	TRPC6 PKD2L1 TRPM3 TRPV2	1.32e-05	27	188	4	16460286
Pubmed	Autophagy proteins control goblet cell function by potentiating reactive oxygen species production.	ATG7 NCF1 NCF1B	1.81e-05	10	188	3	24185898
Pubmed	The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins.	BAZ1B FANCI ATM	2.48e-05	11	188	3	24800743
Pubmed	High glucose promotes pancreatic cancer cell proliferation via the induction of EGF expression and transactivation of EGFR.	EGF EGFR	2.91e-05	2	188	2	22087246
Pubmed	Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency.	MRE11 ATM	2.91e-05	2	188	2	33571423
Pubmed	Ontogenesis and distribution of epidermal growth factor immunoreactivity and binding activity in the mouse fetal and neonatal tissues.	EGF EGFR	2.91e-05	2	188	2	7951532
Pubmed	The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment.	EGF EGFR	2.91e-05	2	188	2	24268047
Pubmed	FRET detects lateral interaction between transmembrane domain of EGF receptor and ganglioside GM3 in lipid bilayers.	EGF EGFR	2.91e-05	2	188	2	33933428
Pubmed	pH dependence of ligand-induced human epidermal growth factor receptor activation investigated by molecular dynamics simulations.	EGF EGFR	2.91e-05	2	188	2	27179806
Pubmed	Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis.	EGF EGFR	2.91e-05	2	188	2	1728582
Pubmed	A polymorphism near osteoprotegerin gene confer risk of obesity in Uyghurs.	TNFRSF11B LRP5	2.91e-05	2	188	2	20960157
Pubmed	Human adult epidermal melanocytes cultured without chemical mitogens express the EGF receptor and respond to EGF.	EGF EGFR	2.91e-05	2	188	2	17334773
Pubmed	Choline redistribution during adaptation to choline deprivation.	ABCB4 PEMT	2.91e-05	2	188	2	17283071
Pubmed	Determining the geometry of oligomers of the human epidermal growth factor family on cells with <10 nm resolution.	EGF EGFR	2.91e-05	2	188	2	26009168
Pubmed	Epidermal growth factor as a biologic switch in hair growth cycle.	EGF EGFR	2.91e-05	2	188	2	12714603
Pubmed	Rapid whole cell imaging reveals a calcium-APPL1-dynein nexus that regulates cohort trafficking of stimulated EGF receptors.	EGFR APPL1	2.91e-05	2	188	2	33597720
Pubmed	Clinical significance of EGF and EGFR expression changes in cryptorchid boys.	EGF EGFR	2.91e-05	2	188	2	12508124
Pubmed	Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer.	FASN EGFR	2.91e-05	2	188	2	29449326
Pubmed	Role of N-glycosylation in EGFR ectodomain ligand binding.	EGF EGFR	2.91e-05	2	188	2	28486782
Pubmed	Cell Force-Driven Basement Membrane Disruption Fuels EGF- and Stiffness-Induced Invasive Cell Dissemination from Benign Breast Gland Acini.	EGF EGFR	2.91e-05	2	188	2	33921304
Pubmed	Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system.	EGF EGFR	2.91e-05	2	188	2	18165319
Pubmed	EGF abrogation-induced fusilli-form dysmorphogenesis of Meckel's cartilage during embryonic mouse mandibular morphogenesis in vitro.	EGF EGFR	2.91e-05	2	188	2	8076525
Pubmed	Epidermal growth factor mutant with wild-type affinity for both ErbB1 and ErbB3.	EGF EGFR	2.91e-05	2	188	2	16584205
Pubmed	Potent SHC tyrosine phosphorylation by epidermal growth factor at low receptor density or in the absence of receptor autophosphorylation sites.	EGF EGFR	2.91e-05	2	188	2	8036006
Pubmed	Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation.	FASN EGFR	2.91e-05	2	188	2	26378037
Pubmed	The epidermal growth factor.	EGF EGFR	2.91e-05	2	188	2	7640657
Pubmed	Detection of epidermal growth factor-urogastrone and its receptor during fetal mouse development.	EGF EGFR	2.91e-05	2	188	2	6248866
Pubmed	Translocation of Epidermal Growth Factor (EGF) to the nucleus has distinct kinetics between adipose tissue-derived mesenchymal stem cells and a mesenchymal cancer cell lineage.	EGF EGFR	2.91e-05	2	188	2	29277356
Pubmed	Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms.	EGF EGFR	2.91e-05	2	188	2	11336639
Pubmed	Association between epidermal growth factor (EGF) and EGF receptor gene polymorphisms and end-stage renal disease and acute renal allograft rejection in a Korean population.	EGF EGFR	2.91e-05	2	188	2	31906817
Pubmed	Complex relationship between ligand binding and dimerization in the epidermal growth factor receptor.	EGF EGFR	2.91e-05	2	188	2	25453753
Pubmed	[Expression of epidermal growth factor receptor and concentrations of epidermal growth factor and melatonin in endometrial carcinoma].	EGF EGFR	2.91e-05	2	188	2	25416211
Pubmed	Amplification of the EGFR gene can be maintained and modulated by variation of EGF concentrations in in vitro models of glioblastoma multiforme.	EGF EGFR	2.91e-05	2	188	2	28934307
Pubmed	FBXW11 deletion alleviates Alzheimer's disease by reducing neuroinflammation and amyloid-β plaque formation via repression of ASK1 signaling.	MAP3K5 FBXW11	2.91e-05	2	188	2	33640602
Pubmed	Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibition.	KCNU1 EGF	2.91e-05	2	188	2	20392696
Pubmed	Effect of epidermal growth factor administration on the development of mouse salivary gland carcinomas.	EGF EGFR	2.91e-05	2	188	2	9890455
Pubmed	Role of epidermal growth factor and its receptor in chemotherapy-induced intestinal injury.	EGF EGFR	2.91e-05	2	188	2	11841993
Pubmed	Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.	EGF EGFR	2.91e-05	2	188	2	21822280
Pubmed	Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events.	EGF EGFR	2.91e-05	2	188	2	25872475
Pubmed	EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.	EGF EGFR	2.91e-05	2	188	2	24704591
Pubmed	EGF/EGFR Promotes Salivary Adenoid Cystic Carcinoma Cell Malignant Neural Invasion via Activation of PI3K/AKT and MEK/ERK Signaling.	EGF EGFR	2.91e-05	2	188	2	35410600
Pubmed	EGFR genomic gain and aberrant pathway signaling in pancreatic cancer patients.	EGF EGFR	2.91e-05	2	188	2	17950068
Pubmed	The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells.	TLR9 TLR10	2.91e-05	2	188	2	12689944
Pubmed	Modulation of focal adhesion constituents and their down-stream events by EGF: On the cross-talk of integrins and growth factor receptors.	EGF EGFR	2.91e-05	2	188	2	26079101
Pubmed	Human cytomegalovirus infection inhibits epidermal growth factor (EGF) signalling by targeting EGF receptors.	EGF EGFR	2.91e-05	2	188	2	12388817
Pubmed	Phosphatidylcholine homeostasis and liver failure.	ABCB4 PEMT	2.91e-05	2	188	2	16144842
Pubmed	Elementary mechanisms producing facilitation of Cav2.1 (P/Q-type) channels.	CACNA1A CACNA2D1	2.91e-05	2	188	2	17438119
Pubmed	Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking.	EGF EGFR	2.91e-05	2	188	2	12162747
Pubmed	Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells.	ACER2 ACER1	2.91e-05	2	188	2	29056331
Pubmed	Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding.	EGF EGFR	2.91e-05	2	188	2	28019699
Pubmed	EGF ligand fused to truncated Pseudomonas aeruginosa exotoxin A specifically targets and inhibits EGFR‑positive cancer cells.	EGF EGFR	2.91e-05	2	188	2	30226622
Pubmed	Mechanosensitive cation currents through TRPC6 and Piezo1 channels in human pulmonary arterial endothelial cells.	PIEZO1 TRPC6	2.91e-05	2	188	2	35968892
Pubmed	The +61 A-G polymorphism of the epidermal growth factor gene is not associated with occurrence of non-melanocytic skin tumors in transplant recipients.	EGF EGFR	2.91e-05	2	188	2	17223314
Pubmed	ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining.	MRE11 ATM	2.91e-05	2	188	2	20647759
Pubmed	Functional effects of glycosylation at Asn-579 of the epidermal growth factor receptor.	EGF EGFR	2.91e-05	2	188	2	16274239
Pubmed	Association study between epidermal growth factor receptor and epidermal growth factor polymorphisms and endometriosis in a Japanese population.	EGF EGFR	2.91e-05	2	188	2	17852426
Pubmed	An association between EGF and EGFR gene polymorphisms with gastric cancer in a Chinese Han population.	EGF EGFR	2.91e-05	2	188	2	22534548
Pubmed	Dynamic distribution of epidermal growth factor during mouse embryo peri-implantation.	EGF EGFR	2.91e-05	2	188	2	12967642
Pubmed	Engineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activation.	EGF EGFR	2.91e-05	2	188	2	21439278
Pubmed	Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation.	EGF EGFR	2.91e-05	2	188	2	2790960
Pubmed	Hypokalaemic periodic paralysis due to the CACNA1S R1239H mutation in a large African family.	CACNA1A CACNA1S	2.91e-05	2	188	2	17418573
Pubmed	Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma.	EGF EGFR	2.91e-05	2	188	2	24928511
Pubmed	Weak power frequency magnetic field acting similarly to EGF stimulation, induces acute activations of the EGFR sensitive actin cytoskeleton motility in human amniotic cells.	EGF EGFR	2.91e-05	2	188	2	24505297
Pubmed	Polyubiquitination of the epidermal growth factor receptor occurs at the plasma membrane upon ligand-induced activation.	EGF EGFR	2.91e-05	2	188	2	10788520
Pubmed	Biological and biochemical activities of a chimeric epidermal growth factor-Elk receptor tyrosine kinase.	EGF EGFR	2.91e-05	2	188	2	8413296
Pubmed	Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.	EGF EGFR	2.91e-05	2	188	2	15837620
Pubmed	Taiwan cobra cardiotoxin III suppresses EGF/EGFR-mediated epithelial-to-mesenchymal transition and invasion of human breast cancer MDA-MB-231 cells.	EGF EGFR	2.91e-05	2	188	2	26774845
Pubmed	EGF-liposomes promote efficient EGFR targeting in xenograft colocarcinoma model.	EGF EGFR	2.91e-05	2	188	2	26892017
Pubmed	Involvement of de novo synthesized palmitate and mitochondrial EGFR in EGF induced mitochondrial fusion of cancer cells.	EGF EGFR	2.91e-05	2	188	2	25483192
Pubmed	Alteration of the serum levels of the epidermal growth factor receptor and its ligands in patients with non-small cell lung cancer and head and neck carcinoma.	EGF EGFR	2.91e-05	2	188	2	17453000
Pubmed	FGFs in endochondral skeletal development.	EGF EGFR	2.91e-05	2	188	2	20564212
Pubmed	Adaptor protein containing PH domain, PTB domain and leucine zipper (APPL1) regulates the protein level of EGFR by modulating its trafficking.	EGFR APPL1	2.91e-05	2	188	2	22037462
Pubmed	Diminished salivary epidermal growth factor secretion: a link between Sjögren's syndrome and autoimmune gastritis?	EGF EGFR	2.91e-05	2	188	2	26399281
Pubmed	[Expression of epidermal growth factor receptor in patients with insulin resistance and seborrheic keratomas].	EGF EGFR	2.91e-05	2	188	2	28791994
Pubmed	Role of epidermal growth factor gene in the development of pancreatic cancer and efficiency of inhibitors of this gene in the treatment of pancreatic carcinoma.	EGF EGFR	2.91e-05	2	188	2	19110611
Pubmed	Effects of epidermal growth factor on preimplantation mouse embryos.	EGF EGFR	2.91e-05	2	188	2	9285326
Pubmed	Receptor overexpression or inhibition alters cell surface dynamics of EGF-EGFR interaction: new insights from real-time single molecule analysis.	EGF EGFR	2.91e-05	2	188	2	19014905
Pubmed	Searching for EGF Fragments Recreating the Outer Sphere of the Growth Factor Involved in Receptor Interactions.	EGF EGFR	2.91e-05	2	188	2	38338748
Pubmed	Inactivation of Autophagy in Keratinocytes Reduces Tumor Growth in Mouse Models of Epithelial Skin Cancer.	ATG7 EGFR	2.91e-05	2	188	2	36429119
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNA1S CACNA2D1 CACNA1G	3.37e-05	26	130	4	253
GeneFamily	Transient receptor potential cation channels	TRPC6 PKD2L1 TRPM3 TRPV2	4.57e-05	28	130	4	249
GeneFamily	Alkaline ceramidases	ACER2 ACER1	1.53e-04	3	130	2	400
GeneFamily	Type 1 receptor serine/threonine kinases	ACVR1C TGFBR1	1.05e-03	7	130	2	345
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3CB PIK3CD	1.40e-03	8	130	2	831
GeneFamily	Trace amine receptors	TAAR6 TAAR9	1.79e-03	9	130	2	188
GeneFamily	CD molecules\|Toll like receptors	TLR9 TLR10	2.22e-03	10	130	2	948
GeneFamily	Chloride voltage-gated channels	BSND CLCN6	2.22e-03	10	130	2	302
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC25A42 APBB1 PLCD4 ZYG11B GPR63 SACS FIG4 AIPL1	2.44e-07	150	187	8	c2c51a3230c978e2fdb1b3ae14193d4014431b25
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPN14 EGFR ACSBG1 TRPM3 SACS TMEM178A DSEL CDK6	1.71e-06	194	187	8	8b81f039f5b25d35a4d5a41b27d4d9360ba22f15
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DEPDC1 EGFR TRPM3 SACS TMEM178A FANCI DSEL CDK6	1.99e-06	198	187	8	7225a6194c52b01c581e58d3cda107c4af96dc4f
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 GRAMD1A UBE4A TMEM178A RRP12 ALG8 PML	4.61e-06	157	187	7	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACER1 SLC35E1 DEPDC1 ANKRD63 RFWD3 PIK3CB FANCI	8.08e-06	171	187	7	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACER1 SLC35E1 DEPDC1 ANKRD63 RFWD3 PIK3CB FANCI	8.08e-06	171	187	7	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	Bronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL16A1 MATN2 ABCB4 TBC1D16 SACS PODN	9.66e-06	116	187	6	b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCell	Dividing_Macrophages-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	NRM PDLIM7 PKD2L1 DEPDC1 BSND FANCI SLC25A19	1.05e-05	178	187	7	6557688c6790a5bcc3b9aea5b8789cf9506b3c54
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A CADPS TMEM178A NEURL1 CACNA1G UNC80 EPHA8	1.50e-05	188	187	7	1efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL16A1 MATN2 LAMA4 EGFR CHRD PODN PID1	1.71e-05	192	187	7	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A ATP13A4 PLCD4 PREX2 EGFR ACSBG1 PLXNB1	1.71e-05	192	187	7	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL16A1 MATN2 LAMA4 EGFR CHRD PODN PID1	1.71e-05	192	187	7	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL16A1 MATN2 LAMA4 EGFR CHRD PODN PID1	1.77e-05	193	187	7	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A GPM6A NRXN2 TMEM178A NEURL1 CACNA1G UNC80	1.77e-05	193	187	7	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A CACNA2D1 COL6A6 FRYL REV3L CADPS UNC80	1.89e-05	195	187	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A CACNA2D1 COL6A6 FRYL REV3L CADPS UNC80	1.89e-05	195	187	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 PDLIM7 MATN2 LAMA4 REV3L MAP3K5 PID1	1.96e-05	196	187	7	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ACAP1 DEPDC1 ADAMTS10 PIK3CD MYEOV NCR1 CDK6	1.96e-05	196	187	7	1cc2b11764584129703ec61965e8ec4e051464e7
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A NPR2 COL16A1 MATN2 LAMA4 EGFR PODN	1.96e-05	196	187	7	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A NPR2 COL16A1 MATN2 LAMA4 EGFR PODN	1.96e-05	196	187	7	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KDELR2 COL16A1 PDLIM7 COL27A1 AOPEP POGLUT2 PLOD1	2.09e-05	198	187	7	c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KDELR2 COL16A1 PDLIM7 COL27A1 AOPEP POGLUT2 PLOD1	2.09e-05	198	187	7	3e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPM6A ATP13A4 DNAH7 MAP3K5 EGFR ACSBG1 TRPM3	2.23e-05	200	187	7	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPM6A ATP13A4 DNAH7 MAP3K5 EGFR ACSBG1 TRPM3	2.23e-05	200	187	7	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPM6A ATP13A4 DNAH7 MAP3K5 EGFR ACSBG1 TRPM3	2.23e-05	200	187	7	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPM6A ATP13A4 DNAH7 MAP3K5 EGFR ACSBG1 TRPM3	2.23e-05	200	187	7	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPM6A ATP13A4 DNAH7 MAP3K5 EGFR ACSBG1 TRPM3	2.23e-05	200	187	7	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NRM SLC25A42 SLC30A4 ABCB4 ADAMTS10 PID1	3.17e-05	143	187	6	5a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NRM SLC25A42 SLC30A4 ABCB4 ADAMTS10 PID1	3.43e-05	145	187	6	997bd540c43725a85ca97e4b79ebe0d336860287
ToppCell	PND01-Immune-Immune_Myeloid-DC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACAP1 PARVG ADCY7 TRPV2 SLC25A19 FGD3	4.46e-05	152	187	6	c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACAP1 PARVG ADCY7 TRPV2 SLC25A19 FGD3	4.46e-05	152	187	6	c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACAP1 PARVG ADCY7 TRPV2 SLC25A19 FGD3	4.46e-05	152	187	6	cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCell	CV-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	ZSWIM8 TENT4B RFWD3 LIPC ANKRD52 CDK6	4.80e-05	154	187	6	26bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAH7 TNFRSF11B FASN SIK2 TRAPPC14 CHP1	5.16e-05	156	187	6	abea3c183d32062b009a79a2bdf861021989c7ef
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	COL16A1 PDLIM7 COL27A1 TRPC6 LAMA4 PODN	5.73e-05	159	187	6	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA4 ACVR1C MAP3K5 FASN PODN PID1	6.14e-05	161	187	6	a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCell	Healthy_Control-Lymphoid-Plasma-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SLC25A42 TLR9 CHKA ABCB4 TLR10 PID1	6.58e-05	163	187	6	b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCell	Healthy_Control-Lymphoid-Plasma\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SLC25A42 TLR9 CHKA ABCB4 TLR10 PID1	6.58e-05	163	187	6	2913ccdd4613472cd82077d4993e1d9f8b223398
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A42 TENT4B COL6A6 EGFR RRP12 PLXNB1	6.58e-05	163	187	6	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRM TMEM175 PARVG RFWD3 PEMT CLCN6	7.77e-05	168	187	6	27cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRE11 ARHGAP39 STRIP2 AOPEP RRP12 POGLUT2	7.77e-05	168	187	6	b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACAP1 ADGRG1 MAGEE1 RUSC2 HINFP PIK3CD	8.03e-05	169	187	6	96aafb687b34d4b59f75c24e176b0b442e864245
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NCF1 PARVG ADCY7 ABCB4 TLR10 MYEOV	8.03e-05	169	187	6	b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NCF1 PARVG ADCY7 ABCB4 TLR10 MYEOV	8.03e-05	169	187	6	2322f03a115c662f808ebfc892192b7d38d48181
ToppCell	control-Myeloid-Mast_cell\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CACNA2D1 NCF1 GPR85 ADCY7 CADPS TRPV2	8.85e-05	172	187	6	c1c99e6732234a6649a79610e99390db0c8f19b0
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S KMT2B NCF1 MAGEE1 TBC1D16 LIPC	9.14e-05	173	187	6	0a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATG2A MON1B KIAA0753 HINFP ACSBG1 FGD3	9.43e-05	174	187	6	1c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCell	NS-control-d_0-4-Myeloid-Mast_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CACNA2D1 NCF1 GPR85 ADCY7 CADPS TRPV2	9.43e-05	174	187	6	2d1f5c17b1551f32f49618ec1bf68eafbfd02ace
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATG2A MON1B KIAA0753 HINFP ACSBG1 FGD3	9.43e-05	174	187	6	5491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL16A1 KMT2B COL27A1 TUBGCP6 RRP12 KLB	9.73e-05	175	187	6	aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPR2 SLC25A42 COL16A1 CLXN SACS PLOD1	9.73e-05	175	187	6	a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPR2 SLC25A42 COL16A1 CLXN SACS PLOD1	9.73e-05	175	187	6	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 PLCD4 PREX2 ACSBG1 PRSS45P PLXNB1	1.00e-04	176	187	6	ac3dc44755280e36c0947b6de3cd639dc17de8b6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACAP1 NCF1 PARVG ADCY7 TLR10 PIK3CD	1.00e-04	176	187	6	d0a3e176df1270968efa79c00dc941c5e1c4f7aa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NCF1 PARVG ADCY7 TLR10 PIK3CD PID1	1.00e-04	176	187	6	926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACAP1 NCF1 PARVG ADCY7 TLR10 PIK3CD	1.00e-04	176	187	6	274458d80f9f3f080248cbf64e4784ef351e7254
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 ACER1 PARVG ADAMTS10 PIK3CD FGD3	1.04e-04	177	187	6	bb496fbec7cacc52847abe2b2714249c47879763
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRM PTPN14 NRXN2 BHMT2 DSEL POGLUT2	1.04e-04	177	187	6	3a85aa2bf3f2fdbea57d22d68e022cb3f6c2eb65
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP13A4 OCA2 LIPC PTPN14 EGFR PIK3CB	1.04e-04	177	187	6	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	droplet-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 COL27A1 PARVG ADCY7 PIK3CD TRPV2	1.07e-04	178	187	6	e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCell	droplet-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 COL27A1 PARVG ADCY7 PIK3CD TRPV2	1.07e-04	178	187	6	12d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCell	droplet-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 COL27A1 PARVG ADCY7 PIK3CD TRPV2	1.07e-04	178	187	6	11c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR2 MON1B PTPN14 ACSBG1 SACS TRPV2	1.17e-04	181	187	6	41969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR2 MON1B PTPN14 ACSBG1 SACS TRPV2	1.17e-04	181	187	6	3f50e61dc2a52d71a5801584617607e6246adcf2
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 RNF213 PTPN4 PIK3CD NCR1 CNGA4	1.21e-04	182	187	6	09d0793245d3d77ab5fc384c0b62637f736da50b
ToppCell	wk_08-11-Hematologic-Myeloid-pre-pDC/DC5\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NCF1 TLR9 PARVG TLR10 UMODL1 PIK3CD	1.21e-04	182	187	6	fec8a2d6d4099722b8e1bb41222108ed74268fcf
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL27A1 TNFRSF11B ABCB4 AOPEP POGLUT2 KLB	1.21e-04	182	187	6	03a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NCF1 PARVG ADCY7 TLR10 CADPS MYEOV	1.24e-04	183	187	6	a97f052950429245c3231464271e1ba539863bba
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	LAMA4 ACVR1C CHKA FASN SIK2 KLB	1.24e-04	183	187	6	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMK+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ACAP1 RNF213 ATG2A GALNT11 ATM EPHA8	1.24e-04	183	187	6	79defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CACNA2D1 ZYG11B REV3L PREX2 BHMT2 APPL1	1.28e-04	184	187	6	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CACNA2D1 MATN2 ADGRG1 CADPS NEURL1	1.32e-04	185	187	6	2088e82e0febdcf05618d3db913d00e2e87812f4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPM6A GPR85 ADGRG1 ADAMTS10 PTPN4 NCR1	1.36e-04	186	187	6	facc1bd8920003ad03d1893c32fc606d82b4d50a
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A MATN2 ACSBG1 TRPM3 BHMT2 UNC80	1.36e-04	186	187	6	ea936e66ae4b7b40564711fad60ac0137327995f
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MATN2 BAZ1B RNF213 CHPF2 DHX35 CDK6	1.40e-04	187	187	6	689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|390C / Donor, Lineage, Cell class and subclass (all cells)	ACAP1 ADGRG1 RNF213 PTPN4 ATM NCR1	1.40e-04	187	187	6	1e8651e6c547384ace5a66b96c6b24a7f390a7ee
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MATN2 BAZ1B RNF213 CHPF2 DHX35 CDK6	1.40e-04	187	187	6	4527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPM6A ATP13A4 CHKA MAP3K5 EGFR TRPM3	1.40e-04	187	187	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A MATN2 ACSBG1 TRPM3 BHMT2 UNC80	1.40e-04	187	187	6	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A MATN2 ACSBG1 TRPM3 BHMT2 UNC80	1.40e-04	187	187	6	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 NCF1 PARVG ADCY7 MAP3K5 TRAPPC14	1.48e-04	189	187	6	c38157c8cf5c0c1f560011ef5cc5892a049ee2b7
ToppCell	18-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	CACNA1A GPM6A PKD2L1 CADPS NEURL1 CHRD	1.48e-04	189	187	6	144beb01b908f2cd0e04513fb84d817e0c3c124e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACAP1 ADGRG1 RNF213 RBM39 PTPN4 ATM	1.48e-04	189	187	6	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A GPM6A NRXN2 TMEM178A UNC80 EPHA8	1.48e-04	189	187	6	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CLXN TRPC6 ANKRD63 ACVR1C STRIP2	1.52e-04	120	187	5	a6d0406a174d46ce06b41280292931954af88a59
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 PDLIM7 LAMA4 CADPS PODN PID1	1.52e-04	190	187	6	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACAP1 ADGRG1 RNF213 RBM39 PTPN4 ATM	1.52e-04	190	187	6	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 PDLIM7 LAMA4 CADPS PODN PID1	1.52e-04	190	187	6	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACAP1 ADGRG1 RNF213 PTPN4 ATM NCR1	1.57e-04	191	187	6	753deb090b7b78b4ef31604dbe5dbfc4dcf5184a
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACAP1 ADGRG1 RNF213 PTPN4 ATM NCR1	1.57e-04	191	187	6	337d7d7b89fe370e1fe005b9daad76c5dc3b8444
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACAP1 ADGRG1 RNF213 PTPN4 ATM NCR1	1.57e-04	191	187	6	355f5bcb220d917163833dead0050fc756c7b260
ToppCell	15-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	CACNA1A CACNA2D1 PKD2L1 CADPS NEURL1 CHRD	1.57e-04	191	187	6	76311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR31 NCF1 RNASEK TNFRSF11B SLC25A19 NCF1B	1.57e-04	191	187	6	7d00796459f4ff0ab7f06a8379b2d34e76b078b2
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC1\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR31 NCF1 PARVG TLR10 TRPV2 CNGA4	1.57e-04	191	187	6	9774d423e448ec2d415261e4ad386a81558129b3
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 TBC1D16 NRXN2 PODN PID1	1.58e-04	121	187	5	e82c9e10b98c8d7ad828cf8ac19a2342014be2ba
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL16A1 COL6A6 LAMA4 EGFR PODN PLOD1	1.61e-04	192	187	6	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NCF1 RNASEK TNFRSF11B SLC25A19 NCF1B EPHA8	1.61e-04	192	187	6	5ea1a8119012eb8bc3100b739a0430377a8ac534
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL16A1 COL6A6 MATN2 LAMA4 PODN PID1	1.66e-04	193	187	6	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	moderate-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CACNA1A RNF213 TNFRSF11B TRPV2 CHRD PML	1.66e-04	193	187	6	22455801194bd8c73c5c397f5eac4f723429c383
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACAP1 COL16A1 MON1B TUBGCP6 LRP5 PLXNB1	1.71e-04	194	187	6	3211d89440a6f4a9b3d4cfb755890816944242ec
Drug	lavendustin A	CACNA1A CACNA1S CACNA2D1 APBB1 EGF EGFR PIK3CB PIK3CD CACNA1G GNRHR	1.58e-06	171	187	10	CID000003894
Drug	lanthanum	CACNA1A CACNA1S CACNA2D1 TRPC6 PKD2L1 ADCY7 CLCN6 ATP2C2 CACNA1G	1.92e-06	136	187	9	CID000023926
Drug	Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; PC3; HT_HG-U133A	PXMP4 CACNA1A CACNA2D1 NPR2 GPR85 PHF8 PREX2 TRPM3 PIK3CD NCR1	5.61e-06	197	187	10	6747_UP
Drug	POPC	GPR85 PLCD4 CHKA SLC30A4 ABCB4 FASN LIPC EGF PEMT PIK3CB PIK3CD GNL3	9.20e-06	306	187	12	CID000065167
Drug	AC1L1JYL	ACER2 SPHK2 NPR2 ACER1 ATG7 PLCD4 GPR63 EGF EGFR TRPM3 SACS PIK3CB PIK3CD EPHA8	1.52e-05	434	187	14	CID000005262
Drug	Diglycerides	TRPC6 FASN EGF GNRHR	1.93e-05	20	187	4	ctd:D004075
Drug	ICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A	BAZ1B RFWD3 RUSC2 HINFP TRPV2 ATM TRAPPC14 PHLPP2 PML	3.38e-05	194	187	9	6165_DN
Drug	Bufexamac [2438-72-4]; Down 200; 18uM; HL60; HT_HG-U133A	ACAP1 CLCN6 IL1RAPL2 ZNF277 LRP5 TRAPPC14 FBXW11 PML CDK6	3.67e-05	196	187	9	2382_DN
Drug	Acetaminophen [103-90-2]; Down 200; 26.4uM; HL60; HT_HG-U133A	ZSWIM8 PTPN4 AOPEP PIK3CD TRPV2 LRP5 CHPF2 GNA12 ZNF749	3.67e-05	196	187	9	3025_DN
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A	SPHK2 LAMA4 BAZ1B TNFRSF11B MAP3K5 IL1RAPL2 DHX35 ATM PML	3.82e-05	197	187	9	3934_DN
Drug	Terconazole [67915-31-5]; Down 200; 7.6uM; PC3; HT_HG-U133A	PXMP4 CACNA1A PDLIM7 LAMA4 RRP12 TRAPPC14 GNRHR PML CDK6	3.82e-05	197	187	9	4583_DN
Drug	Norethynodrel [68-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A	NPR2 PDLIM7 PDK3 APBB1 BAZ1B RUSC2 PEMT ATP2C2 DHX35	3.97e-05	198	187	9	1818_DN
Drug	Iohexol [66108-95-0]; Down 200; 4.8uM; MCF7; HT_HG-U133A	PDLIM7 ADGRG1 OCA2 ADCY7 TNFRSF11B RUSC2 TGFBR1 SLC30A5 NEURL1	3.97e-05	198	187	9	5704_DN
Drug	gadolinium	CACNA1A CACNA1S CACNA2D1 TRPC6 SLC30A5 TRPM3 SACS TRPV2 CACNA1G	4.13e-05	199	187	9	CID000023982
Drug	Dichlorodiphenyl Dichloroethylene	CACNA1A NCF1 TLR9 ACVR1C TNFRSF11B FASN EGF NRXN2 EGFR CACNA1G EPHA8	4.29e-05	302	187	11	ctd:D003633
Drug	AC1L1KC5	CACNA1A KDELR2 CACNA1S CACNA2D1 TRPC6 GPR85 MAP3K5 EGF EGFR SACS PIK3CB PIK3CD ATP2C2 TRPV2 CACNA1G	4.34e-05	541	187	15	CID000005428
Drug	nisoldipine	CACNA1A CACNA1S CACNA2D1 EGF CACNA1G GNL3	4.46e-05	78	187	6	CID000004499
Drug	tetrabromobisphenol A	CACNA1A NRM ACAP1 SPHK2 COL27A1 APBB1 RNF213 MAGEE1 CHKA PARVG RUSC2 FASN EGF EGFR ACSBG1 RRP12 CACNA1G DSEL PLXNB1 PML	4.73e-05	891	187	20	ctd:C020806
Drug	AC1NBU2S	CACNA1A CACNA1S CACNA2D1 NPR2 DAD1 EGF CACNA1G	5.22e-05	117	187	7	CID004473765
Disease	endometrial cancer (is_implicated_in)	MRE11 EGF PIK3CD ATM	6.49e-05	36	178	4	DOID:1380 (is_implicated_in)
Disease	lymphocyte count	KDELR2 CACNA1S ACAP1 SPHK2 PIEZO1 PKD2L1 TNIP1 PREX2 TNFRSF11B TBC1D16 PTPN4 LIPC EGF NRXN2 EGFR ACSBG1 UMODL1 PIK3CD MYEOV ATM SETD3 CDK6	7.66e-05	1464	178	22	EFO_0004587
Disease	lung non-small cell carcinoma (is_marker_for)	KDM3B TLR9 PREX2 EGF EGFR ATM CDK6	7.83e-05	169	178	7	DOID:3908 (is_marker_for)
Disease	Malignant neoplasm of breast	MRE11 ACAP1 PDLIM7 UBR4 TNIP1 OCA2 MAGEE1 FASN PTPN14 EGF EGFR IL1RAPL2 PIK3CB ZNF277 APPL1 ATM PLOD1 PLXNB1	9.39e-05	1074	178	18	C0006142
Disease	Inherited neuropathies	MRE11 SPG11 SACS ATM	9.87e-05	40	178	4	C0598589
Disease	lupus nephritis (is_marker_for)	TLR9 TNFRSF11B EGF	1.38e-04	17	178	3	DOID:0080162 (is_marker_for)
Disease	high grade glioma (implicated_via_orthology)	ATG7 EGFR PIK3CB PIK3CD	1.44e-04	44	178	4	DOID:3070 (implicated_via_orthology)
Disease	body fat distribution	ADAMTS10 UBE4A AIPL1 GNA12 MTCH2 GNL3 CDK6	2.36e-04	202	178	7	EFO_0004341
Disease	lobe attachment	CACNA1S PLCD4 MON1B PREX2 TNFRSF11B SACS FGD3	2.74e-04	207	178	7	EFO_0007667
Disease	chronic granulomatous disease (implicated_via_orthology)	NCF1 NCF1B	3.58e-04	5	178	2	DOID:3265 (implicated_via_orthology)
Disease	polycystic liver disease (is_implicated_in)	LRP5 ALG8	3.58e-04	5	178	2	DOID:0050770 (is_implicated_in)
Disease	psoriasis, coronary artery disease	COQ10A ANKRD52	3.58e-04	5	178	2	EFO_0000676, EFO_0001645
Disease	Polycystic liver disease	LRP5 ALG8	3.58e-04	5	178	2	C0158683
Disease	liposarcoma	FASN CDK6	5.34e-04	6	178	2	C0023827
Disease	aspartate aminotransferase to alanine aminotransferase ratio	PXMP4 BAZ1B PKD2L1 ARHGAP39 ABCB4 CLCN6 CDK6	6.47e-04	239	178	7	EFO_0010934
Disease	response to antidepressant	RTP2 MROH5 MON1B SLC26A8 EGFR NEURL1	7.20e-04	176	178	6	GO_0036276
Disease	focal segmental glomerulosclerosis (implicated_via_orthology)	TRPC6 LIPC	7.45e-04	7	178	2	DOID:1312 (implicated_via_orthology)
Disease	palmitoleic acid measurement	ACER1 PKD2L1	7.45e-04	7	178	2	EFO_0007973
Disease	birth weight	TENT4B BAZ1B ACVR1C ADCY7 PTPN14 UMODL1 GNA12 PML CDK6	7.49e-04	399	178	9	EFO_0004344
Disease	breast size	PTPN4 KCNU1 CADPS MYEOV	8.15e-04	69	178	4	EFO_0004884
Disease	obsessive-compulsive symptom measurement	ATP13A4 PEMT CADPS	8.57e-04	31	178	3	EFO_0007802
Disease	Diabetes Mellitus	NCF1 MAP3K5 APPL1	9.41e-04	32	178	3	C0011849
Disease	female breast cancer (is_implicated_in)	FANCI ATM	9.89e-04	8	178	2	DOID:0050671 (is_implicated_in)
Disease	Liver carcinoma	GPM6A KMT2B ATG7 DEPDC1 ABCB4 FASN EGF EGFR FANCI ATM	1.07e-03	507	178	10	C2239176
Disease	Malignant Neoplasms	MRE11 FASN EGFR ATM CDK6	1.10e-03	128	178	5	C0006826
Disease	Glioblastoma	EGF EGFR PML CDK6	1.35e-03	79	178	4	C0017636
Disease	Human papillomavirus infectious disease (is_marker_for)	TLR9 EGFR	1.58e-03	10	178	2	DOID:11166 (is_marker_for)
Disease	Head and Neck Carcinoma	EGFR PIK3CB	1.58e-03	10	178	2	C3887461
Disease	Fanconi anemia (is_implicated_in)	RFWD3 FANCI	1.58e-03	10	178	2	DOID:13636 (is_implicated_in)
Disease	Giant Cell Glioblastoma	EGF EGFR PML CDK6	1.70e-03	84	178	4	C0334588
Disease	Shortened QT interval	CACNA2D1 LRP5	1.92e-03	11	178	2	C0151879
Disease	daytime rest measurement	CACNA1A TRPC6 TNIP1 TRPM3 CADPS GNA12 HCRTR2	2.17e-03	295	178	7	EFO_0007828
Disease	rheumatoid arthritis (implicated_via_orthology)	NCF1 NCF1B	2.30e-03	12	178	2	DOID:7148 (implicated_via_orthology)
Disease	Malignant Head and Neck Neoplasm	EGFR PIK3CB FANCI	2.38e-03	44	178	3	C0278996
Disease	schizophrenia (is_marker_for)	TNFRSF11B EGF EGFR	2.38e-03	44	178	3	DOID:5419 (is_marker_for)
Disease	glioblastoma (is_marker_for)	PIK3CB PIK3CD CDK6	2.38e-03	44	178	3	DOID:3068 (is_marker_for)
Disease	colorectal cancer (is_marker_for)	KDM3B FASN EGFR PIK3CB ATM	2.69e-03	157	178	5	DOID:9256 (is_marker_for)
Disease	Sjogren's Syndrome	NCF1 TNIP1	2.70e-03	13	178	2	C1527336
Disease	Sicca Syndrome	NCF1 TNIP1	2.70e-03	13	178	2	C0086981
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	PKD2L1 LIPC	2.70e-03	13	178	2	OBA_2045082
Disease	monocyte count	KDELR2 PIEZO1 TRPC6 RTP2 PKD2L1 ZYG11B PREX2 MAP3K5 OR52I2 EGF EGFR PIK3CD RRP12 GNA12 MYEOV ATM CDK6	2.73e-03	1320	178	17	EFO_0005091
Disease	Cardiomyopathy, Dilated	FASN EGFR ATM	3.06e-03	48	178	3	C0007193
Disease	dystonia (is_implicated_in)	KMT2B AOPEP	3.14e-03	14	178	2	DOID:543 (is_implicated_in)
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	PKD2L1 LRP5	3.14e-03	14	178	2	DOID:898 (implicated_via_orthology)
Disease	nausea and vomiting of pregnancy severity measurement	TRPC6 HCRTR2	3.14e-03	14	178	2	EFO_0009265
Disease	early cardiac repolarization measurement	LRP5 MGAT5B	3.14e-03	14	178	2	EFO_0004885
Disease	cortical surface area measurement	CACNA1A CACNA2D1 NPR2 PCNX3 FRYL ARHGAP39 DNAH7 TBC1D16 EGFR CADPS AOPEP PIK3CD GNA12 SETD3 MTCH2 PID1 CDK6	3.30e-03	1345	178	17	EFO_0010736
Disease	Cardiomyopathy, Familial Idiopathic	FASN EGFR ATM	3.44e-03	50	178	3	C1449563
Disease	tumor necrosis factor measurement	APBB1 LIPC	3.61e-03	15	178	2	EFO_0010834
Disease	lysophosphatidylethanolamine 18:0 measurement	MATN2 LIPC	3.61e-03	15	178	2	EFO_0010367
Disease	Familial thoracic aortic aneurysm and aortic dissection	ADAMTS10 TGFBR1 PLOD1	4.05e-03	53	178	3	C4707243
Disease	Dermatitis	EGF EGFR	4.11e-03	16	178	2	C0011603
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	PIK3CD ATM	4.11e-03	16	178	2	C0334634
Disease	lung adenocarcinoma	TRPC6 TNIP1 UBE4A PIK3CB ATM	4.17e-03	174	178	5	EFO_0000571
Disease	Amyotrophic lateral sclerosis	SPG11 FIG4	4.64e-03	17	178	2	cv:C0002736
Disease	Uremia	TNFRSF11B TGFBR1	4.64e-03	17	178	2	C0041948
Disease	Glioblastoma Multiforme	EGF EGFR PML CDK6	4.65e-03	111	178	4	C1621958
Disease	myeloid white cell count	ACAP1 SPHK2 PIEZO1 GRAMD1A TRPC6 PREX2 MAP3K5 LIPC EGF GNA12 OSCP1 PLXNB1 CDK6	4.65e-03	937	178	13	EFO_0007988
Disease	age at onset, Parkinson disease	TMEM175 OCA2	5.20e-03	18	178	2	EFO_0004847, MONDO_0005180
Disease	Libman-Sacks Disease	PCNX3 NCF1 TNIP1	5.22e-03	58	178	3	C0242380
Disease	atrophic macular degeneration, age-related macular degeneration, wet macular degeneration	TGFBR1 LIPC TRPM3	5.74e-03	60	178	3	EFO_0001365, EFO_0004683, EFO_1001492
Disease	reasoning	ANKRD52 PID1	5.78e-03	19	178	2	EFO_0004350
Disease	Intellectual Disability	KDM3B CSDE1 FASN NRXN2 TRPM3 SACS CACNA1G FBXW11	5.96e-03	447	178	8	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
LHGAGNFVTEMQLFI	UMODL1	1106	Q5DID0
FFQALMLLFRSATGE	CACNA1A	1741	O00555
NFITGSRVIFHFRTM	AIPL1	26	Q9NZN9
FHMTLSFLGQLLDEI	ACER1	76	Q8TDN7
FHATLSFLGQMLDEL	ACER2	81	Q5QJU3
IFNILLSLAMHIAGF	ATP13A4	976	Q4VNC1
LSLAMHIAGFILVQR	ATP13A4	981	Q4VNC1
ANVTGFNLIHRLSLM	COL16A1	46	Q07092
IREAQTFSRMHVLLG	BAZ1B	1156	Q9UIG0
HFLLDLSRSVGMAFL	GPR31	91	O00270
TVMLRHENILGFIAA	ACVR1C	241	Q8NER5
LFQMVHTQRQLGDAF	ARFIP1	186	P53367
RMFFHFSEILDGNQL	CSDE1	371	O75534
LVMEGHLFKRASNAF	ACAP1	266	Q15027
FLAVGRDVHTFAFIM	APBB1	611	O00213
MFQLLRGLDFLHSHR	CDK6	126	Q00534
FHGQLILSQDFLQML	AOPEP	616	Q8N6M6
MRDVQFNHLTRFIGA	NPR2	571	P20594
RHQAILGMAFLVLAV	ADCY7	61	P51828
AFADNVSGLRMLLQH	ANKRD52	866	Q8NB46
TKLIFEIGFLRNHMF	ATP2C2	861	O75185
MHSVVQLFQGFRDLL	ATG2A	1751	Q2TAZ0
FHVGAERLQQMLFSD	GRAMD1A	376	Q96CP6
LGLMFEVTHAFRSQD	ADAMTS10	16	Q9H324
FLEAMQAGKVHLARF	ANKRD63	16	C9JTQ0
FHVITLRSMVQFIGR	MTCH2	141	Q9Y6C9
SLHFNITEDMLRGIF	RBM39	256	Q14498
IFEIVHRTLAAMLGS	OCA2	346	Q04671
DMFDGLILHHLFQRL	PARVG	71	Q9HBI0
TNFISGLQRLHGMLE	RFWD3	121	Q6PCD5
FLRVLIQHLDTSFME	ARHGAP39	1066	Q9C0H5
LHESRETLLGFNMVN	PTPN4	276	P29074
RLGFLGLLHMEVFNQ	GUF1	401	Q8N442
DGQMFRHILNFLRLG	KCTD19	441	Q17RG1
LLLGTQREAFHAMAA	MON1B	351	Q7L1V2
LFLMAVSFLQLHPRE	TENT4B	286	Q8NDF8
FDHASLFEMVQRLTL	CADPS	676	Q9ULU8
MQLGTLLTFFHELVQ	FANCI	1136	Q9NVI1
MILHNQITGIGREDF	PODN	386	Q7Z5L7
DFLFASTILHLVVMN	DAD1	96	P61803
NRTMHFVTEFVLLGF	OR11H6	21	Q8NGC7
GLLHSMIQILFTFQL	OR4C15	151	Q8NGM1
LALKHMFERSFTQGE	MATN2	736	O00339
VLSFIFIMGNHARES	MAGEE1	841	Q9HCI5
HTAQNLLRMGLAFLV	NCR1	251	O76036
ELNMTFHLFIVALAG	GPM6A	206	P51674
MSAVVAQTLHVFGLR	CFAP57	1	Q96MR6
SILHQLFIVRFLGSM	APPL1	496	Q9UKG1
LDFVMDILVFHSSRQ	LRP5	886	O75197
AVFRSNLSHLLDLMG	MGAT5B	231	Q3V5L5
ARTLIMIFLASGTHF	PID1	31	Q7Z2X4
HSAMLFVQALLSGLF	PCNX3	1271	Q9H6A9
FTVQMGNLRFSLGHV	PLXNB1	1461	O43157
IFFVHLFTGSEMVLL	OR4K15	101	Q8NH41
FTQIFLLHLLGGVEM	OR4K17	101	Q8NGC6
MGDTFIRHIALLGFE	NCF1	1	P14598
EAVLHLRFSNGLMVT	FBXW11	321	Q9UKB1
RSIFPQQSLRHSLFM	FRYL	1061	O94915
HLKFSSELGMIFNER	GALNT11	91	Q8NCW6
LAFRTLQRNGLMLHT	NRXN2	316	Q9P2S2
LLAGRLVSFLMDHHQ	DEPDC1	666	Q5TB30
LGLQARDLRFQHVMS	MRS2	111	Q9HD23
RFLSDANGLHLFQMG	KDM3B	146	Q7LBC6
SLLMFTRQAGHFVEG	MYEOV	56	Q96EZ4
HEMKTRFLLFGETNQ	LIPC	46	P11150
LLFVGQHSLMAAERV	NRM	71	Q8IXM6
HMAGSVQFRQLQLFK	TUBGCP6	1656	Q96RT7
LHFQGQFRDHIEMLL	KCNU1	81	A8MYU2
FDMFNFLASQHRVLP	KMT2B	2521	Q9UMN6
VIMGIFSNISSIHRF	FGD3	196	Q5JSP0
MFFHLTLAGAEVFLL	OR2T34	106	Q8NGX1
LSTLLGNGFMIFLIH	OR13H1	36	Q8NG92
VLLIMSFDRFLAIHN	OR51A2	116	Q8NGJ7
VLLIMSFDRFLAIHN	OR51A4	116	Q8NGJ6
DNRFLTLMGTSLHLV	NBPF1	1191	Q3BBV0
SFRILAHLTGTEFMQ	PDLIM7	166	Q9NR12
MGDTFIRHIALLGFE	NCF1B	1	A6NI72
DVFMFLTNRHTLGHL	PLOD1	491	Q02809
GHMRFRDVILVFSAI	ABCB4	966	P21439
MRNHTTVANFILLGL	OR6C74	1	A6NCV1
LLLNFLRSHCFTQAM	PEMT	61	Q9UBM1
SILNVLKRVFGMFAH	HCRTR2	321	O43614
LGTFEDHFLSLQRMF	EGFR	41	P00533
MFDTHQAARLLNLGR	EXOSC10	386	Q01780
GFHEVLNNLISRISM	ATM	2536	Q13315
SQVFNLFRTMGLRHL	CLCN6	821	P51797
INAALGFDTFVVMRH	ATG7	496	O95352
LFLLALGTFLMSHDR	BSND	16	Q8WZ55
VRQLHMEFLRAGSNV	BHMT2	56	Q9H2M3
MLNRLSDPVNHFFFL	GNRHR	296	P30968
RHATFRNFGMAFLTL	CACNA1G	1781	O43497
QHNLFAMSLFGDRIF	EGF	246	P01133
SMRNQILKHFDIGFT	CACNA1S	826	Q13698
RIFHGEKLMNTNLIF	CACNA2D1	1001	P54289
VAALHFDQMFQRFGS	FIG4	356	Q92562
FHISVIRGGLSNMLF	CHKA	111	P35790
ALGIDNVLRFHFMSP	DHX35	436	Q9H5Z1
LDTFLRTHDGQFTIM	EPHA8	721	P29322
EFRSLLHSQLATMFF	COQ10A	196	Q96MF6
MNLVLFRFAIEHISR	DNAH7	2311	Q8WXX0
STFLKQMRIIHGREF	GNA12	71	Q03113
MAETQHFFLGLNIRL	ACSBG1	456	Q96GR2
HMNLLLAVFLLDTSF	ADGRG1	446	Q9Y653
EFAISRVQMNFLHLL	COL27A1	1741	Q8IZC6
SLEFFTVLAQRRGMH	GNL3	361	Q9BVP2
FTTRFVMHEQLAGSR	KLB	826	Q86Z14
SFMGILNTLRHNALR	GPR63	261	Q9BZJ6
HRSFRANDSLGFMLL	GPR85	176	P60893
MNLFRFLGDLSHLLA	KDELR1	1	P24390
GLRHSQDLAFLSMLN	FASN	441	P49327
GMFANNTKFLDHIRR	HINFP	206	Q9BQA5
HIFQERMDLLSGNFL	SACS	3631	Q9NZJ4
FVFMLLVDQIGNSHV	SLC39A9	116	Q9NUM3
FGLVSFLMHAGLERN	SLC39A9	191	Q9NUM3
LKLHFFQEVLGASMR	DSEL	1011	Q8IZU8
MNIFRLTGDLSHLAA	KDELR2	1	P33947
TGHLLIQGRDFLSQM	C18orf63	121	Q68DL7
QFHFNLRTVRDLSMF	COL6A6	181	A6NMZ7
ENDFMTLFLAHGRLV	LAMA4	1516	Q16363
MFFVHLATAVETGLL	OR52I2	131	Q8NH67
HKFRLFQTLEMVIGA	MROH5	141	Q6ZUA9
FLGASVLANDHMRVI	MAP3K5	481	Q99683
HTMRFNAFILGLLNI	RUSC2	1101	Q8N2Y8
VILFHMFLDRAQRAG	RTP2	71	Q5QGT7
FNTGFLKRMLFESLH	TRMT1L	536	Q7Z2T5
FTIVFHGRRSNLDLM	PLCD4	91	Q9BRC7
HFSRLSVLNIEMNFI	TLR10	486	Q9BXR5
VVMFTLGGFEHLQTL	STRIP2	276	Q9ULQ0
HFLEMSRNKFIGFTL	STRIP2	431	Q9ULQ0
AVFGNLLVMISILHF	TAAR6	46	Q96RI8
AAFGNLLVMIAILHF	TAAR9	46	Q96RI9
TQHVAGLLFLMTGIF	TMEM178A	206	Q8NBL3
VALHIMLSQLTFIFG	SLC26A8	236	Q96RN1
IFELESRLHNMLVSG	IL1RAPL2	486	Q9NP60
EVGLQHFLSFLSSMR	PML	656	P29590
HLGIFFMGIFVRNRI	PTPN14	231	Q15678
DRILQAMGNIALAFH	SETD3	146	Q86TU7
FNEQVLRLMHSLGID	SIK2	296	Q9H0K1
ISFTTFDLMQILLRH	SLC25A42	301	Q86VD7
AHRGAIRALQMFVTQ	KIAA0753	306	Q2KHM9
HGNLFITLFALMLTA	PIK3CB	996	P42338
RLLNILGCHAVFFMI	SLC35E1	221	Q96K37
LHTVRQFFMEDIVLA	MRE11	301	P49959
TLLIFFQDLHIRVSM	OSCP1	171	Q8WVF1
FRMLINQHTLLFGGD	PDK3	161	Q15120
NAFALLVEMGHAFLR	RRP12	876	Q5JTH9
LVEMGHAFLRFGSNQ	RRP12	881	Q5JTH9
TVMLRHENILGFIAA	TGFBR1	251	P36897
SIARLFQKRHMEGAF	ALG8	176	Q9BVK2
DQVNFRGFMRTLAHF	CHP1	76	Q99653
GLEVMDVFLRFSGLH	CHPF2	701	Q9P2E5
RGAHMLLQNELFLNV	CHRD	491	Q9H2X0
LLDMVVRFHTGFLEQ	CNGA4	81	Q8IV77
NAFRNILHVTFGMTD	CLXN	51	Q9HAE3
LTQEEFLNRLMIHGS	SPG11	496	Q96JI7
FTHLGRMALEFNRLA	TNIP1	181	Q15025
RAFIMGDVALVHLQT	PRSS45P	76	Q7RTY3
QAFIDLHSAGNMLFR	RNF213	1621	Q63HN8
TCRHFIENQGLELFM	ZYG11B	531	Q9C0D3
GHANLTFEQLRSLME	TNFRSF11B	286	O00300
KLFMDSFTLGRHQRV	ZNF749	361	O43361
SRFSVGIFHLMQIAV	TMEM175	441	Q9BSA9
IMLFLNVFNGALILH	UNC80	2186	Q8N2C7
GRVFHRINDSAVMLF	NEURL1	176	O76050
VFMANTFLVSHRKLG	PHLPP2	851	Q6ZVD8
SEMARLFGIQFLHVL	REV3L	2541	O60673
LRLFLAMERGSHFSL	SPHK2	581	Q9NRA0
FQALRTGLFELSQHM	TRAPPC14	456	Q8WVR3
ASLAGLHALRFLFMD	TLR9	161	Q9NR96
MHGIFFRSLDETTLR	TLR9	371	Q9NR96
FVKLLIENGVSMHRF	TRPM3	526	Q9HCF6
VDLGHMRSLRLFFSD	TBC1D16	301	Q8TBP0
AFQEQLHFRGMVLLL	TRPV2	611	Q9Y5S1
GLLFLHLFALMRAAG	PIK3CD	971	O00329
TLEFLVSAFLHRMNQ	PREX2	41	Q70Z35
VGFHIFRTLEVNRLM	PKD2L1	401	Q9P0L9
EHVGFRIFMDAILLS	POGLUT2	206	Q6UW63
NFGFSLLRKISMRHD	SERPINA10	81	Q9UK55
AALMLFFLHLGIFIR	TMEM262	21	E9PQX1
HNLAFRVGMFALELQ	ZSWIM8	851	A7E2V4
EFLGNRSVILNHMAR	ZNF277	181	Q9NRM2
RFTFGFHRLEVLSAM	SLC30A4	171	O14863
NANMRGVFLHVLADT	SLC30A5	586	Q8TAD4
FGGNFLHSLNIEMQL	PHF8	366	Q9UPP1
DLVQLMALFFHRSQL	PIEZO1	1786	Q92508
HAASFTIFLGLLVMN	TRPC6	446	Q9Y210
SLFVHPFLAERIISM	UBE4A	866	Q14139
IMLGIFFNVHSAVLI	RNASEK	66	Q6P5S7
RNGFHSLVIDVTMAL	UBR4	296	Q5T4S7
LQMLLLIFHNFTETG	UBR4	811	Q5T4S7
PHALVMTFLFRNGSL	PXMP4	46	Q9Y6I8
QFLSFEMLTELVHRG	SLC25A19	96	Q9HC21
FLDFLTNKHMGILNE	YEATS2	1406	Q9ULM3
SLNFHLIDFNLLMVT	TMEM39B	116	Q9GZU3