Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	denatured protein binding	HSPA1A HSPA1B	1.23e-05	3	41	2	GO:0031249
GeneOntologyMolecularFunction	death receptor agonist activity	HSPA1A HSPA1B	4.10e-05	5	41	2	GO:0038177
GeneOntologyMolecularFunction	bile acid:sodium symporter activity	SLC10A3 SLC10A5	6.14e-05	6	41	2	GO:0008508
GeneOntologyMolecularFunction	ATP-dependent protein disaggregase activity	HSPA1A HSPA1B	6.14e-05	6	41	2	GO:0140545
GeneOntologyMolecularFunction	C3HC4-type RING finger domain binding	HSPA1A HSPA1B	6.14e-05	6	41	2	GO:0055131
GeneOntologyMolecularFunction	transcription factor binding	GATA2 PHF1 RARG KLF4 HSPA1A HSPA1B PIM1 EBF4	1.25e-04	753	41	8	GO:0008134
GeneOntologyMolecularFunction	histone deacetylase binding	HIC1 KLF4 HSPA1A HSPA1B	2.31e-04	147	41	4	GO:0042826
GeneOntologyMolecularFunction	monocarboxylate:sodium symporter activity	SLC10A3 SLC10A5	4.25e-04	15	41	2	GO:0140161
GeneOntologyMolecularFunction	protein-containing complex destabilizing activity	HSPA1A HSPA1B	4.25e-04	15	41	2	GO:0140776
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	SLCO4A1 SLC10A3 SLC10A5	4.52e-04	73	41	3	GO:0170055
GeneOntologyMolecularFunction	misfolded protein binding	HSPA1A HSPA1B	6.16e-04	18	41	2	GO:0051787
GeneOntologyMolecularFunction	secondary active monocarboxylate transmembrane transporter activity	SLC10A3 SLC10A5	6.88e-04	19	41	2	GO:0015355
GeneOntologyMolecularFunction	death receptor activity	HSPA1A HSPA1B	8.43e-04	21	41	2	GO:0005035
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	GATA2 RARG KLF4 HSPA1A HSPA1B EBF4	1.13e-03	582	41	6	GO:0140297
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	GATA2 RARG KLF4 HSPA1A HSPA1B	1.57e-03	417	41	5	GO:0061629
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC10A3 SLC45A1 SLC10A5	1.87e-03	119	41	3	GO:0015294
GeneOntologyMolecularFunction	bile acid transmembrane transporter activity	SLC10A3 SLC10A5	2.21e-03	34	41	2	GO:0015125
GeneOntologyMolecularFunction	organic acid:sodium symporter activity	SLC10A3 SLC10A5	2.34e-03	35	41	2	GO:0005343
GeneOntologyMolecularFunction	NF-kappaB binding	HSPA1A HSPA1B	2.48e-03	36	41	2	GO:0051059
GeneOntologyMolecularFunction	transcription regulator inhibitor activity	HSPA1A HSPA1B	2.48e-03	36	41	2	GO:0140416
GeneOntologyMolecularFunction	disordered domain specific binding	HSPA1A HSPA1B	2.90e-03	39	41	2	GO:0097718
GeneOntologyMolecularFunction	transcription coregulator binding	GATA2 PHF1 KLF4	2.96e-03	140	41	3	GO:0001221
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSPA1A HSPA1B	3.05e-03	40	41	2	GO:0140662
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLCO4A1 SLC10A3 SLC45A1 SLC10A5	3.11e-03	296	41	4	GO:0015291
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	GATA2 FOXI2 POU3F1 RARG KLF4 HSF5 NFKB2 EBF4	3.35e-03	1244	41	8	GO:0000978
GeneOntologyMolecularFunction	symporter activity	SLC10A3 SLC45A1 SLC10A5	3.59e-03	150	41	3	GO:0015293
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	GATA2 FOXI2 POU3F1 RARG KLF4 HSF5 NFKB2 EBF4	3.83e-03	1271	41	8	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	GATA2 FOXI2 POU3F1 HIC1 RARG KLF4 NFKB2 EBF4	7.19e-03	1412	41	8	GO:0000981
GeneOntologyMolecularFunction	lipid transporter activity	SLCO4A1 SLC10A3 SLC10A5	7.55e-03	196	41	3	GO:0005319
GeneOntologyMolecularFunction	protein domain specific binding	GATA2 FZD8 SRCIN1 HSPA1A HSPA1B SHANK3	8.43e-03	875	41	6	GO:0019904
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	GATA2 FOXI2 POU3F1 RARG KLF4 HSF5 NFKB2 EBF4	8.70e-03	1459	41	8	GO:0000977
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLC10A3 SLC10A5	9.09e-03	70	41	2	GO:1901618
GeneOntologyMolecularFunction	protein folding chaperone	HSPA1A HSPA1B	9.86e-03	73	41	2	GO:0044183
GeneOntologyBiologicalProcess	response to lipid	GATA2 SLC10A3 RARG KLF4 HSPA1A HSPA1B MN1 PIM1 ADCY8 NFKB2	5.36e-05	1126	41	10	GO:0033993
GeneOntologyBiologicalProcess	positive regulation of erythrocyte differentiation	GATA2 HSPA1A HSPA1B	5.40e-05	37	41	3	GO:0045648
GeneOntologyBiologicalProcess	cellular heat acclimation	HSPA1A HSPA1B	5.75e-05	6	41	2	GO:0070370
GeneOntologyBiologicalProcess	heat acclimation	HSPA1A HSPA1B	8.04e-05	7	41	2	GO:0010286
GeneOntologyBiologicalProcess	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	HSPA1A HSPA1B	8.04e-05	7	41	2	GO:0070434
GeneOntologyBiologicalProcess	positive regulation of microtubule nucleation	HSPA1A HSPA1B	1.07e-04	8	41	2	GO:0090063
GeneOntologyBiologicalProcess	positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	HSPA1A HSPA1B	1.07e-04	8	41	2	GO:0070426
GeneOntologyBiologicalProcess	cellular response to nutrient	MN1 PDK2 PIM1	1.78e-04	55	41	3	GO:0031670
GeneOntologyBiologicalProcess	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	HSPA1A HSPA1B	2.10e-04	11	41	2	GO:0070432
GeneOntologyBiologicalProcess	regulation of erythrocyte differentiation	GATA2 HSPA1A HSPA1B	2.31e-04	60	41	3	GO:0045646
GeneOntologyBiologicalProcess	vitamin D receptor signaling pathway	MN1 PIM1	2.51e-04	12	41	2	GO:0070561
GeneOntologyBiologicalProcess	negative regulation of inclusion body assembly	HSPA1A HSPA1B	2.51e-04	12	41	2	GO:0090084
GeneOntologyBiologicalProcess	positive regulation of tumor necrosis factor-mediated signaling pathway	HSPA1A HSPA1B	3.46e-04	14	41	2	GO:1903265
GeneOntologyBiologicalProcess	regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	HSPA1A HSPA1B	4.55e-04	16	41	2	GO:0070424
HumanPheno	Abnormality of the periungual region	KRT16 KRT17 NFKB2	1.95e-05	22	13	3	HP:0100803
HumanPheno	Steatocystoma multiplex	KRT16 KRT17	3.60e-05	4	13	2	HP:0012035
HumanPheno	Eruptive vellus hair cyst	KRT16 KRT17	3.60e-05	4	13	2	HP:0025248
HumanPheno	Linear arrays of macular hyperkeratoses in flexural areas	KRT16 KRT17	5.99e-05	5	13	2	HP:0007490
HumanPheno	Hyperplastic callus formation	KRT16 KRT17	5.99e-05	5	13	2	HP:0030268
HumanPheno	Onychogryposis of toenails	KRT16 KRT17	1.25e-04	7	13	2	HP:0008401
HumanPheno	Onychogryposis	KRT16 KRT17	1.25e-04	7	13	2	HP:0001819
HumanPheno	Onychogryposis of fingernail	KRT16 KRT17	2.14e-04	9	13	2	HP:0040036
Domain	BilAc:Na_symport/Acr3	SLC10A3 SLC10A5	9.33e-05	7	40	2	IPR002657
Domain	SBF	SLC10A3 SLC10A5	9.33e-05	7	40	2	PF01758
Domain	HSP70	HSPA1A HSPA1B	5.27e-04	16	40	2	PF00012
Domain	HSP70_2	HSPA1A HSPA1B	5.96e-04	17	40	2	PS00329
Domain	HSP70_3	HSPA1A HSPA1B	5.96e-04	17	40	2	PS01036
Domain	HSP70_1	HSPA1A HSPA1B	5.96e-04	17	40	2	PS00297
Domain	Hsp_70_fam	HSPA1A HSPA1B	6.70e-04	18	40	2	IPR013126
Domain	IPT	NFKB2 EBF4	1.52e-03	27	40	2	SM00429
Domain	IPT	NFKB2 EBF4	2.13e-03	32	40	2	IPR002909
Domain	Keratin_I	KRT16 KRT17	4.00e-03	44	40	2	IPR002957
Domain	-	GATA2 RARG	6.63e-03	57	40	2	3.30.50.10
Domain	Znf_NHR/GATA	GATA2 RARG	6.85e-03	58	40	2	IPR013088
Domain	Intermediate_filament_CS	KRT16 KRT17	8.04e-03	63	40	2	IPR018039
Domain	Filament	KRT16 KRT17	1.01e-02	71	40	2	SM01391
Domain	IF	KRT16 KRT17	1.04e-02	72	40	2	PS00226
Domain	Filament	KRT16 KRT17	1.07e-02	73	40	2	PF00038
Domain	IF	KRT16 KRT17	1.15e-02	76	40	2	IPR001664
Pubmed	Upregulation of the constitutively expressed HSC70 by KLF4.	KLF4 HSPA1A HSPA1B	6.08e-09	4	41	3	18379898
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	GATA2 SLCO4A1 PRR12 GAS2L1 SLC10A3 SETD1B SLC45A1 RARG KLF4 NFKB2	4.60e-07	1105	41	10	35748872
Pubmed	A census of human transcription factors: function, expression and evolution.	GATA2 FOXI2 POU3F1 HIC1 RARG KLF4 HSF5 NFKB2 EBF4	8.96e-07	908	41	9	19274049
Pubmed	Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.	HSPA1A HSPA1B	1.36e-06	2	41	2	12411538
Pubmed	Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.	HSPA1A HSPA1B	1.36e-06	2	41	2	2868009
Pubmed	Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.	HSPA1A HSPA1B	1.36e-06	2	41	2	25618331
Pubmed	Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.	HSPA1A HSPA1B	1.36e-06	2	41	2	24328534
Pubmed	In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.	HSPA1A HSPA1B	1.36e-06	2	41	2	3786141
Pubmed	Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.	HSPA1A HSPA1B	1.36e-06	2	41	2	16679378
Pubmed	Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout mice.	HSPA1A HSPA1B	1.36e-06	2	41	2	19639652
Pubmed	Effect of mutation of amino acids 246-251 (KRKHKK) in HSP72 on protein synthesis and recovery from hypoxic injury.	HSPA1A HSPA1B	1.36e-06	2	41	2	16100242
Pubmed	Role of the C-terminal region of mouse inducible Hsp72 in the recognition of peptide substrate for chaperone activity.	HSPA1A HSPA1B	1.36e-06	2	41	2	15498567
Pubmed	Biological activity of truncated C-terminus human heat shock protein 72.	HSPA1A HSPA1B	1.36e-06	2	41	2	21094186
Pubmed	Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.	HSPA1A HSPA1B	1.36e-06	2	41	2	26923070
Pubmed	Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.	HSPA1A HSPA1B	1.36e-06	2	41	2	16482515
Pubmed	Geranylgeranylaceton induces heat shock protein 72 in skeletal muscle cells.	HSPA1A HSPA1B	1.36e-06	2	41	2	17482577
Pubmed	Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.	HSPA1A HSPA1B	1.36e-06	2	41	2	11864979
Pubmed	Structure and expression of an inducible HSP70-encoding gene from Mus musculus.	HSPA1A HSPA1B	1.36e-06	2	41	2	8076831
Pubmed	The 70 kDa heat shock protein protects against experimental traumatic brain injury.	HSPA1A HSPA1B	1.36e-06	2	41	2	23816752
Pubmed	Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.	HSPA1A HSPA1B	1.36e-06	2	41	2	15719414
Pubmed	Keratin 16 regulates innate immunity in response to epidermal barrier breach.	KRT16 KRT17	1.36e-06	2	41	2	24218583
Pubmed	Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.	HSPA1A HSPA1B	1.36e-06	2	41	2	26976620
Pubmed	Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.	HSPA1A HSPA1B	1.36e-06	2	41	2	21187371
Pubmed	Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.	HSPA1A HSPA1B	1.36e-06	2	41	2	20430459
Pubmed	Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.	HSPA1A HSPA1B	1.36e-06	2	41	2	20235222
Pubmed	Genetic determinants of HSP70 gene expression following heat shock.	HSPA1A HSPA1B	1.36e-06	2	41	2	20876613
Pubmed	The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.	HSPA1A HSPA1B	1.36e-06	2	41	2	20223214
Pubmed	Structure of a new crystal form of human Hsp70 ATPase domain.	HSPA1A HSPA1B	1.36e-06	2	41	2	10216320
Pubmed	Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.	HSPA1A HSPA1B	1.36e-06	2	41	2	20093776
Pubmed	Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.	HSPA1A HSPA1B	1.36e-06	2	41	2	23704948
Pubmed	Effects of voluntary exercise and genetic selection for high activity levels on HSP72 expression in house mice.	HSPA1A HSPA1B	1.36e-06	2	41	2	14672969
Pubmed	Structure and expression of the human gene encoding major heat shock protein HSP70.	HSPA1A HSPA1B	1.36e-06	2	41	2	2858050
Pubmed	Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.	HSPA1A HSPA1B	1.36e-06	2	41	2	17513788
Pubmed	IL-6 activates HSP72 gene expression in human skeletal muscle.	HSPA1A HSPA1B	1.36e-06	2	41	2	12207910
Pubmed	Genetic Modulation of HSPA1A Accelerates Kindling Progression and Exerts Pro-convulsant Effects.	HSPA1A HSPA1B	1.36e-06	2	41	2	29964156
Pubmed	Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.	HSPA1A HSPA1B	1.36e-06	2	41	2	28837204
Pubmed	Molecular cloning of sequences encoding the human heat-shock proteins and their expression during hyperthermia.	HSPA1A HSPA1B	1.36e-06	2	41	2	3019832
Pubmed	Sequence analysis of HSPA1A and HSPA1B in a multi-ethnic study population.	HSPA1A HSPA1B	1.36e-06	2	41	2	17364813
Pubmed	Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance.	HSPA1A HSPA1B	1.36e-06	2	41	2	24430435
Pubmed	Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse.	HSPA1A HSPA1B	1.36e-06	2	41	2	22940431
Pubmed	Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals.	HSPA1A HSPA1B	1.36e-06	2	41	2	29572464
Pubmed	Protective effect of heat shock proteins 70.1 and 70.3 on retinal photic injury after systemic hyperthermia.	HSPA1A HSPA1B	1.36e-06	2	41	2	15988927
Pubmed	The role of heat shock protein 70 in mediating age-dependent mortality in sepsis.	HSPA1A HSPA1B	1.36e-06	2	41	2	21296977
Pubmed	The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages.	HSPA1A HSPA1B	1.36e-06	2	41	2	17617616
Pubmed	Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.	HSPA1A HSPA1B	1.36e-06	2	41	2	26448330
Pubmed	Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells.	HSPA1A HSPA1B	1.36e-06	2	41	2	29323151
Pubmed	HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts.	HSPA1A HSPA1B	1.36e-06	2	41	2	12714332
Pubmed	Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.	HSPA1A HSPA1B	1.36e-06	2	41	2	19299581
Pubmed	Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene.	HSPA1A HSPA1B	1.36e-06	2	41	2	11713291
Pubmed	[Molecular Mechanism of KLF4 Up-regulating Keratin 17 Expression in Keratinocytes].	KRT17 KLF4	1.36e-06	2	41	2	33236603
Pubmed	Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice.	HSPA1A HSPA1B	1.36e-06	2	41	2	21108992
Pubmed	The septic shock associated HSPA1B1267 polymorphism influences production of HSPA1A and HSPA1B.	HSPA1A HSPA1B	1.36e-06	2	41	2	15232679
Pubmed	Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).	HSPA1A HSPA1B	1.36e-06	2	41	2	31320473
Pubmed	Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors.	HSPA1A HSPA1B	1.36e-06	2	41	2	38703814
Pubmed	Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle.	HSPA1A HSPA1B	1.36e-06	2	41	2	23812373
Pubmed	Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease.	HSPA1A HSPA1B	1.36e-06	2	41	2	19605647
Pubmed	hsp72, a host determinant of measles virus neurovirulence.	HSPA1A HSPA1B	1.36e-06	2	41	2	16971451
Pubmed	Human immunodeficiency virus-1 Nef suppresses Hsp70-mediated Tat activation.	HSPA1A HSPA1B	1.36e-06	2	41	2	21970979
Pubmed	Induction of heat shock protein 70 inhibits ischemic renal injury.	HSPA1A HSPA1B	1.36e-06	2	41	2	21270764
Pubmed	[Relationship between heat stress protein 70 gene polymorphisms and the risk of acute mountain sickness].	HSPA1A HSPA1B	1.36e-06	2	41	2	15748471
Pubmed	Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage.	HSPA1A HSPA1B	1.36e-06	2	41	2	20849898
Pubmed	Heat shock protein 70 promotes lipogenesis in HepG2 cells.	HSPA1A HSPA1B	1.36e-06	2	41	2	29631603
Pubmed	Coordinated post-transcriptional regulation of Hsp70.3 gene expression by microRNA and alternative polyadenylation.	HSPA1A HSPA1B	1.36e-06	2	41	2	21757701
Pubmed	Inducible heat shock protein 70 prevents multifocal flat dysplastic lesions and invasive tumors in an inflammatory model of colon cancer.	HSPA1A HSPA1B	1.36e-06	2	41	2	19005184
Pubmed	Role of membrane Hsp70 in radiation sensitivity of tumor cells.	HSPA1A HSPA1B	1.36e-06	2	41	2	26197988
Pubmed	Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis.	HSPA1A HSPA1B	1.36e-06	2	41	2	16361353
Pubmed	Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression.	HSPA1A HSPA1B	1.36e-06	2	41	2	17234954
Pubmed	Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis.	HSPA1A HSPA1B	1.36e-06	2	41	2	22792201
Pubmed	A genome-wide investigation into parent-of-origin effects in autism spectrum disorder identifies previously associated genes including SHANK3.	GALNT17 SHANK3	1.36e-06	2	41	2	27876814
Pubmed	Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.	HSPA1A HSPA1B	1.36e-06	2	41	2	3931075
Pubmed	Inhibition of hsp70-1 and hsp70-3 expression disrupts preimplantation embryogenesis and heightens embryo sensitivity to arsenic.	HSPA1A HSPA1B	1.36e-06	2	41	2	9820195
Pubmed	Surface expression of a C-terminal alpha-helix region in heat shock protein 72 on murine LL/2 lung carcinoma can be recognized by innate immune sentinels.	HSPA1A HSPA1B	1.36e-06	2	41	2	19157555
Pubmed	Tumor necrosis factor alpha and inflammation disrupt the polarity complex in intestinal epithelial cells by a posttranslational mechanism.	HSPA1A HSPA1B	1.36e-06	2	41	2	21135124
Pubmed	Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions.	HSPA1A HSPA1B	1.36e-06	2	41	2	37298493
Pubmed	Heat-shock protein 70 genes and human longevity: a view from Denmark.	HSPA1A HSPA1B	1.36e-06	2	41	2	16804002
Pubmed	Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy.	HSPA1A HSPA1B	1.36e-06	2	41	2	16735677
Pubmed	HspA1A, a 70-kDa heat shock protein, differentially interacts with anionic lipids.	HSPA1A HSPA1B	1.36e-06	2	41	2	26476215
Pubmed	Impact of hepatic HSP72 on insulin signaling.	HSPA1A HSPA1B	1.36e-06	2	41	2	30532989
Pubmed	Functional region of mouse heat shock protein 72 for its binding to lymphoid neoplastic P388D1 cells.	HSPA1A HSPA1B	1.36e-06	2	41	2	17126904
Pubmed	Syntenic conservation of HSP70 genes in cattle and humans.	HSPA1A HSPA1B	1.36e-06	2	41	2	1478667
Pubmed	Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses.	GATA2 HSPA1A HSPA1B	3.03e-06	24	41	3	18755693
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	GATA2 POU3F1 HIC1 RARG KLF4 HSF5 NFKB2	3.13e-06	544	41	7	28473536
Pubmed	Novel and recurrent mutations in the genes encoding keratins K6a, K16 and K17 in 13 cases of pachyonychia congenita.	KRT16 KRT17	4.06e-06	3	41	2	11886499
Pubmed	Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species.	HSPA1A HSPA1B	4.06e-06	3	41	2	15671022
Pubmed	Chromosomal location of human genes encoding major heat-shock protein HSP70.	HSPA1A HSPA1B	4.06e-06	3	41	2	3470951
Pubmed	Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice.	HSPA1A HSPA1B	4.06e-06	3	41	2	14701760
Pubmed	Negative Regulation of IKKε-Mediated IRF7 Phosphorylation by HSP70.	HSPA1A HSPA1B	4.06e-06	3	41	2	32169844
Pubmed	Analysis of heat shock protein 70 gene polymorphisms Mexican patients with idiopathic pulmonary fibrosis.	HSPA1A HSPA1B	4.06e-06	3	41	2	26496868
Pubmed	Hyperthermia increases interleukin-6 in mouse skeletal muscle.	HSPA1A HSPA1B	4.06e-06	3	41	2	22673618
Pubmed	Heat stress induced arginylation of HuR promotes alternative polyadenylation of Hsp70.3 by regulating HuR stability and RNA binding.	HSPA1A HSPA1B	4.06e-06	3	41	2	32929216
Pubmed	Genetic polymorphisms of HSP70 in age-related cataract.	HSPA1A HSPA1B	4.06e-06	3	41	2	23666708
Pubmed	Heat-shock response increases lung injury caused by Pseudomonas aeruginosa via an interleukin-10-dependent mechanism in mice.	HSPA1A HSPA1B	4.06e-06	3	41	2	24667831
Pubmed	Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders.	HSPA1A HSPA1B	4.06e-06	3	41	2	24726381
Pubmed	Heat-shock protein 70 antagonizes apoptosis-inducing factor.	HSPA1A HSPA1B	4.06e-06	3	41	2	11533664
Pubmed	Heat-shock protein gene polymorphisms and the risk of nephropathy in patients with Type 2 diabetes.	HSPA1A HSPA1B	4.06e-06	3	41	2	18518860
Pubmed	Genetic interaction of Hsp70 family genes polymorphisms with high-altitude pulmonary edema among Chinese railway constructors at altitudes exceeding 4000 meters.	HSPA1A HSPA1B	4.06e-06	3	41	2	19351530
Pubmed	Stress-induced localization of HSPA6 (HSP70B') and HSPA1A (HSP70-1) proteins to centrioles in human neuronal cells.	HSPA1A HSPA1B	4.06e-06	3	41	2	24061851
Pubmed	Interacting contribution of the five polymorphisms in three genes of Hsp70 family to essential hypertension in Uygur ethnicity.	HSPA1A HSPA1B	4.06e-06	3	41	2	19085089
Pubmed	Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies.	HSPA1A HSPA1B	4.06e-06	3	41	2	11779758
Pubmed	Cell-lineage-specific expression of the mouse hsp68 gene during embryogenesis.	HSPA1A HSPA1B	4.06e-06	3	41	2	3582732
Cytoband	7q11.23	ELN SSC4D GALNT17	9.19e-05	97	41	3	7q11.23
Cytoband	Ensembl 112 genes in cytogenetic band chr6p21	PHF1 HSPA1A HSPA1B PIM1	1.05e-03	503	41	4	chr6p21
Cytoband	6p21.3	PHF1 HSPA1A HSPA1B	1.46e-03	250	41	3	6p21.3
Cytoband	17q21.2	KRT16 KRT17	1.81e-03	70	41	2	17q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	ELN SSC4D GALNT17	1.84e-03	271	41	3	chr7q11
GeneFamily	Solute carriers	SLCO4A1 SLC10A3 SLC45A1 SLC10A5 SLC22A23	2.19e-04	395	26	5	752
GeneFamily	Heat shock 70kDa proteins	HSPA1A HSPA1B	2.67e-04	17	26	2	583
GeneFamily	Keratins, type I	KRT16 KRT17	7.35e-04	28	26	2	608
Coexpression	GAUTAM_EYE_IRIS_CILIARY_BODY_MEG3_HIGH_FIBROBLASTS	HIC1 ELN KRT16 KRT17 PTPRG HSPA1A HSPA1B	4.57e-10	113	41	7	M43610
Coexpression	HOLLERN_SQUAMOUS_BREAST_TUMOR	GATA2 POU3F1 KRT16 KRT17 KLF4 PIM1	2.81e-07	173	41	6	M650
Coexpression	HOLLERN_SQUAMOUS_BREAST_TUMOR	GATA2 POU3F1 KRT16 KRT17 KLF4 PIM1	7.40e-07	204	41	6	MM966
Coexpression	GERY_CEBP_TARGETS	HGSNAT KLF4 HSPA1A HSPA1B PIM1	1.87e-06	131	41	5	M12338
Coexpression	GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_DN	HGSNAT FZD8 FOXI2 HSPA1A TMEM200B	2.98e-06	144	41	5	M345
Coexpression	GERY_CEBP_TARGETS	HGSNAT KLF4 HSPA1A HSPA1B PIM1	5.00e-06	160	41	5	MM1155
Coexpression	CUI_DEVELOPING_HEART_VASCULAR_ENDOTHELIAL_CELL	GATA2 ELN KLF4 HSPA1A HSPA1B	1.24e-05	193	41	5	M39321
Coexpression	GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_UP	ELN PTPRG KLF4 ADCY8 NFKB2	1.47e-05	200	41	5	M8222
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5	KLF4 HSPA1A HSPA1B	1.71e-05	32	41	3	MM1278
Coexpression	BENPORATH_EED_TARGETS	GATA2 FZD8 SLCO4A1 POU3F1 HIC1 KLF4 HSPA1A HSPA1B ADCY8	3.02e-05	1059	41	9	M7617
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HENDO	GATA2 HIC1 ELN RARG PTPRG KLF4 SHANK3 SLC22A23	5.95e-05	888	41	8	M39049
Coexpression	TABULA_MURIS_SENIS_SUBCUTANEOUS_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING	HIC1 RARG HSPA1A HSPA1B MN1	6.40e-05	272	41	5	MM3825
Coexpression	TABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING	PHF1 HIC1 ELN RARG HSPA1A HSPA1B MN1	8.38e-05	685	41	7	MM3782
Coexpression	KRISHNAN_FURIN_TARGETS_UP	HSPA1A HSPA1B	1.07e-04	10	41	2	MM1243
Coexpression	WONG_ADULT_TISSUE_STEM_MODULE	GATA2 MPDZ SARAF KLF4 HSPA1A HSPA1B SHANK3	1.15e-04	721	41	7	M1999
Coexpression	KIM_WT1_TARGETS_12HR_UP	SLC10A3 HSPA1A HSPA1B MN1	1.31e-04	166	41	4	M15535
Coexpression	MA_RAT_AGING_DN	ELN KLF4 HSPA1A HSPA1B	1.43e-04	170	41	4	MM16097
Coexpression	VANHARANTA_UTERINE_FIBROID_DN	GATA2 KLF4 HSPA1A	1.59e-04	67	41	3	M13879
Coexpression	PHONG_TNF_RESPONSE_NOT_VIA_P38	GATA2 SLCO4A1 HSPA1A HSPA1B NFKB2	1.85e-04	341	41	5	M2504
Coexpression	MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	CCDC125 PHF1 FOXI2 SLC45A1 RARG HSF5	1.89e-04	544	41	6	M1936
Coexpression	MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	CCDC125 PHF1 FOXI2 SLC45A1 RARG HSF5	2.52e-04	574	41	6	MM820
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR	GATA2 FZD8 HIC1 SARAF KLF4 MN1	2.52e-04	574	41	6	M8215
Coexpression	GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN	SARAF SLC45A1 RARG KRT16	2.62e-04	199	41	4	M5070
Coexpression	GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN	HGSNAT SLC10A3 HIC1 SARAF	2.62e-04	199	41	4	M9697
Coexpression	GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP	PHF1 SETD1B HSPA1A PDK2	2.62e-04	199	41	4	M3187
Coexpression	GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP	HIC1 KLF4 HSPA1B MN1	2.67e-04	200	41	4	M5994
Coexpression	GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP	HIC1 SRCIN1 HSPA1A HSPA1B	2.67e-04	200	41	4	M9652
Coexpression	GSE17721_LPS_VS_CPG_6H_BMDC_UP	POU3F1 IDH3G HSPA1B NFKB2	2.67e-04	200	41	4	M3998
Coexpression	GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP	GATA2 SARAF SETD1B PIM1	2.67e-04	200	41	4	M7535
Coexpression	GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_UP	GAS2L1 PDK2 PIM1 EBF4	2.67e-04	200	41	4	M8703
Coexpression	FUJIWARA_PARK2_HEPATOCYTE_PROLIFERATION_UP	HSPA1A HSPA1B	2.83e-04	16	41	2	MM559
Coexpression	CUI_DEVELOPING_HEART_C5_VALVAR_CELL	ELN RARG HSPA1A HSPA1B	2.93e-04	205	41	4	M39302
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR	GATA2 FZD8 HIC1 SARAF KLF4 MN1	3.19e-04	600	41	6	MM1025
Coexpression	SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER	POU3F1 HIC1 KLF4	3.55e-04	88	41	3	M11288
Coexpression	SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN	MPDZ RARG	3.59e-04	18	41	2	MM687
Coexpression	SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN	MPDZ RARG	3.59e-04	18	41	2	M1620
Coexpression	KAMIKUBO_MYELOID_MN1_NETWORK	GAS2L1 MN1	4.01e-04	19	41	2	MM884
Coexpression	KAMIKUBO_MYELOID_MN1_NETWORK	GAS2L1 MN1	4.01e-04	19	41	2	M2093
Coexpression	LAMB_CCND1_TARGETS	HSPA1A HSPA1B	4.46e-04	20	41	2	M2935
Coexpression	ZHANG_UTERUS_C2_SECRETORY_STROMAL3_RAMP3_HIGH_CELL	ELN KLF4 HSPA1A HSPA1B	4.46e-04	229	41	4	MM16607
Coexpression	BLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_DEL_NS1_INFECTION_UP	FZD8 SLCO4A1 POU3F1 KLF4 HSPA1B NFKB2	4.65e-04	644	41	6	M34026
Coexpression	IGARASHI_ATF4_TARGETS_DN	KLF4 HSPA1A HSPA1B	4.87e-04	98	41	3	M4779
Coexpression	GESERICK_TERT_TARGETS_DN	ELN KLF4	4.92e-04	21	41	2	M15891
Coexpression	DELLA_RESPONSE_TO_TSA_AND_BUTYRATE	GATA2 HSPA1A	4.92e-04	21	41	2	M7912
Coexpression	GESERICK_TERT_TARGETS_DN	ELN KLF4	4.92e-04	21	41	2	MM1085
Coexpression	TIAN_TNF_SIGNALING_NOT_VIA_NFKB	GATA2 HSPA1A	5.41e-04	22	41	2	M14666
Coexpression	TABULA_MURIS_SENIS_TRACHEA_BASAL_EPITHELIAL_CELL_OF_TRACHEOBRONCHIAL_TREE_AGEING	HSPA1A HSPA1B	5.41e-04	22	41	2	MM3854
Coexpression	ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	HSPA1A HSPA1B MN1 SLC22A23 NFKB2	6.70e-04	452	41	5	M18685
Coexpression	WOOD_EBV_EBNA1_TARGETS_UP	SLCO4A1 HSPA1A HSPA1B	6.83e-04	110	41	3	M1696
Coexpression	GENTILE_UV_LOW_DOSE_UP	HSPA1A HSPA1B	7.00e-04	25	41	2	M17864
Coexpression	DEN_INTERACT_WITH_LCA5	HSPA1A HSPA1B	7.58e-04	26	41	2	M1380
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	GATA2 SLCO4A1 GAS2L1 ELN SHANK3	4.60e-07	168	41	5	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	Endothelial-A-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	GATA2 SLCO4A1 HSPA1A HSPA1B SHANK3	7.60e-07	186	41	5	796cbae2a417502aaf0891fc9c382bbfd88967fe
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	GATA2 SLCO4A1 HSPA1A HSPA1B SHANK3	7.80e-07	187	41	5	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Adult / Lineage, Cell type, age group and donor	GATA2 SLCO4A1 HSPA1A HSPA1B SHANK3	8.01e-07	188	41	5	e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_follicular_helper_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PHF1 SLCO4A1 SARAF PIM1 NFKB2	8.89e-07	192	41	5	3e2a0f332e7f9833ba88f3c809cee78b65090401
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SARAF KLF4 HSPA1A HSPA1B SHANK3	8.89e-07	192	41	5	7197e401e563441ab94815f7619e032ebef9e586
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 PTPRG KLF4 HSPA1A HSPA1B	9.12e-07	193	41	5	1772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 PTPRG KLF4 HSPA1A HSPA1B	9.12e-07	193	41	5	e4b440d50ae7391b26924778be6d9d53e0692449
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 PTPRG KLF4 HSPA1A HSPA1B	9.12e-07	193	41	5	e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCell	IPF-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	GATA2 PTPRG HSPA1A HSPA1B MN1	9.84e-07	196	41	5	8f0f72ead06abe02b575e443552eacc2151077ef
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GATA2 KLF4 HSPA1A HSPA1B SHANK3	1.01e-06	197	41	5	b2b7f8dc8ca421441e4c99c4f5d18fbc1668d79f
ToppCell	11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	ELN GALNT17 RARG KLF4 MN1	1.01e-06	197	41	5	9a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GATA2 SLCO4A1 PTPRG KLF4 SHANK3	1.09e-06	200	41	5	e6d36be0c4c569e27303bb4e4f34cd2187e9759d
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Macrophages\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	GATA2 SLCO4A1 PTPRG KLF4 SHANK3	1.09e-06	200	41	5	c0c51719cf81512c50bfcc2fed883c867e522d2a
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GATA2 SLCO4A1 PTPRG KLF4 SHANK3	1.09e-06	200	41	5	758840c31f2ddd7ccf7bf13252ebb48d33e89479
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GATA2 SLCO4A1 PTPRG KLF4 SHANK3	1.09e-06	200	41	5	c37fe06a94e5779c56e01389869bb432d3bbaebc
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GATA2 ELN KLF4 SHANK3	1.48e-05	162	41	4	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CCDC125 HIC1 TMEM200B	1.59e-05	53	41	3	d55030028f9ac970afb343ef6e1c41ab4bb2ae53
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CCDC125 HIC1 TMEM200B	1.59e-05	53	41	3	c8af66760dac32cdbc0f17d1c004596c847f16f6
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	GATA2 SLCO4A1 KLF4 SHANK3	1.63e-05	166	41	4	76b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|368C / Donor, Lineage, Cell class and subclass (all cells)	GATA2 SLCO4A1 KLF4 SHANK3	1.63e-05	166	41	4	30a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell	Adult-Immune-enucleated_erythrocyte-D122\|Adult / Lineage, Cell type, age group and donor	PHF1 HSPA1A HSPA1B SHANK3	1.75e-05	169	41	4	d5624e5b3687bd3f18f3a2b47a94d11eb1fbdb75
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GATA2 MPDZ SLC10A5 SHANK3	1.79e-05	170	41	4	5bb577e2c4bd275fbe4ee23ff8c007b2fcb90e56
ToppCell	(00)_Basal-(1)_24hpi\|(00)_Basal / shred by cell type and Timepoint	KRT16 KRT17 KLF4 HSPA1B	1.91e-05	173	41	4	a8e62e7d8baf6af691acd5c50deedbadc119ceba
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors\|lymph-node_spleen / Manually curated celltypes from each tissue	GATA2 MPDZ MN1 SHANK3	1.96e-05	174	41	4	6d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCell	droplet-Bladder-nan-24m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELN GALNT17 KRT17 HSPA1A	2.19e-05	179	41	4	dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HSPA1A HSPA1B SHANK3 SLC22A23	2.19e-05	179	41	4	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	severe-Others-CD34+_GATA2+_cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	GATA2 ELN SLC10A5 SHANK3	2.19e-05	179	41	4	dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 SLCO4A1 GAS2L1 PIM1	2.24e-05	180	41	4	ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 SLCO4A1 GAS2L1 PIM1	2.24e-05	180	41	4	4e9e8cde2919610c4ac0025b1c9819808048bc1d
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 SLCO4A1 GAS2L1 PIM1	2.24e-05	180	41	4	466381bf93c3da6a2a241daadb68e9aad2964eae
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 ELN PTPRG KLF4	2.33e-05	182	41	4	ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 ELN PTPRG KLF4	2.33e-05	182	41	4	e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 ELN PTPRG KLF4	2.33e-05	182	41	4	b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU3F1 SRCIN1 GALNT17 SLC22A23	2.33e-05	182	41	4	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175\|Adult / Lineage, Cell type, age group and donor	GATA2 HSPA1A HSPA1B SHANK3	2.33e-05	182	41	4	8b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GATA2 HIC1 PTPRG SHANK3	2.38e-05	183	41	4	ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	GAS2L1 HIC1 ELN PTPRG	2.49e-05	185	41	4	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	GATA2 SLCO4A1 ELN SHANK3	2.49e-05	185	41	4	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	(00)_Basal-(4)_1wkpi\|(00)_Basal / shred by cell type and Timepoint	KRT17 KLF4 HSPA1A HSPA1B	2.49e-05	185	41	4	bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HSPA1A HSPA1B PIM1 SLC22A23	2.49e-05	185	41	4	e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell	Immune-enucleated_erythrocyte\|World / Lineage, Cell type, age group and donor	HSPA1A HSPA1B PIM1 SLC22A23	2.54e-05	186	41	4	f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCell	severe_influenza-RBC\|World / disease group, cell group and cell class (v2)	HSPA1A HSPA1B PIM1 SLC22A23	2.59e-05	187	41	4	f846750575f318503d21ade30f5bfd2e1d4c84af
ToppCell	Endothelial-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	GATA2 SLCO4A1 ELN SHANK3	2.59e-05	187	41	4	fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCell	Influenza_Severe-RBC\|World / Disease group and Cell class	HSPA1A HSPA1B PIM1 SLC22A23	2.65e-05	188	41	4	f0438e6a77ee1f0456cb65926685266fff470983
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	GATA2 HIC1 ELN GALNT17	2.65e-05	188	41	4	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Mega-Mast\|lymph-node_spleen / Manually curated celltypes from each tissue	GATA2 GAS2L1 HSPA1A SHANK3	2.65e-05	188	41	4	8e80e0714883e5c5e372d933682c5b55ebef7e62
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GATA2 FOXI2 KLF4 HSPA1A	2.65e-05	188	41	4	36459e5b91cbd7336a502d96b0dc37ca560ae4d6
ToppCell	droplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 ELN KLF4 MN1	2.71e-05	189	41	4	2ce330d8078833c05775c481e73770f9ee4a5c88
ToppCell	(02)_Cycling_Basal_(regeneration)-(1)_24hpi\|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint	KRT17 KLF4 HSPA1A HSPA1B	2.71e-05	189	41	4	311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 ELN KLF4 MN1	2.71e-05	189	41	4	473c87036e04a058b4a5138438b7ba7e1e766799
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ELN KLF4 MN1 SHANK3	2.76e-05	190	41	4	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	GATA2 PTPRG KLF4 SHANK3	2.76e-05	190	41	4	5130fb325f80f591b9b36beacb8072c4472304f2
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	GATA2 SLCO4A1 PTPRG SHANK3	2.76e-05	190	41	4	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 ELN KLF4 MN1	2.76e-05	190	41	4	5bf3d0beee69879c95265d07fba023626a7cc808
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	ELN GALNT17 HSPA1A HSPA1B	2.76e-05	190	41	4	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLCO4A1 HSPA1A HSPA1B SHANK3	2.76e-05	190	41	4	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 ELN KLF4 MN1	2.76e-05	190	41	4	cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCell	PND01-03-samps-Endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	GATA2 PTPRG KLF4 SHANK3	2.76e-05	190	41	4	1357bd4527399d7013ee33272bda7453f472999a
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 PTPRG KLF4 SLC22A23	2.82e-05	191	41	4	718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCell	COVID-19-kidney-Stressed_EC\|kidney / Disease (COVID-19 only), tissue and cell type	HIC1 HSPA1A HSPA1B SHANK3	2.82e-05	191	41	4	d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 PTPRG KLF4 SLC22A23	2.82e-05	191	41	4	454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCell	PND01-Endothelial\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 PTPRG KLF4 SHANK3	2.82e-05	191	41	4	96b9b0aaf0cb2d6f929ff563dbaedc83ffb4795e
ToppCell	Control-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	GATA2 SLCO4A1 PTPRG SHANK3	2.82e-05	191	41	4	c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PTPRG MN1 SHANK3 SLC22A23	2.88e-05	192	41	4	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|World / Lineage, Cell type, age group and donor	GATA2 SLCO4A1 KLF4 SHANK3	2.88e-05	192	41	4	1e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GATA2 SLCO4A1 PTPRG SHANK3	2.94e-05	193	41	4	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 PTPRG KLF4 SHANK3	2.94e-05	193	41	4	30254658a2023ea9808cdd786530b966a1446418
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 PTPRG KLF4 SHANK3	2.94e-05	193	41	4	b6b065b0c2ad31d1488dfa970450b29a8ac1f3aa
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 PTPRG KLF4 SHANK3	2.94e-05	193	41	4	4513e6cb3f86d9cc56e7892fbe11a861335bd179
ToppCell	droplet-Kidney-nan-21m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 RARG KLF4 MN1	2.94e-05	193	41	4	0e39b6c8e7382e61a9891f6c7e3df2a859788219
ToppCell	(6)_Endothelial-C_(Capillary_Aerocyte_)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	GATA2 SLCO4A1 KLF4 SHANK3	2.94e-05	193	41	4	f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GATA2 SLCO4A1 PTPRG SHANK3	3.00e-05	194	41	4	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	Severe-CD4+_T\|World / Disease group and Cell class	PHF1 SARAF RARG PIM1	3.00e-05	194	41	4	2ad888f78765ecfb8d1ea978c75c90fa3030509a
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GATA2 SLCO4A1 PTPRG SHANK3	3.00e-05	194	41	4	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	COPD-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	GATA2 SLCO4A1 PTPRG SHANK3	3.00e-05	194	41	4	68705a6eca947c5b42b943d5224a7aef2a744007
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU3F1 KRT17 KLF4 HSPA1A	3.06e-05	195	41	4	17c4d3b59cd0d79ce9ae5dde95586f3e923db16f
ToppCell	saliva-Mild-Moderate_progression_d12-25\|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)	KRT16 KRT17 HSPA1A HSPA1B	3.06e-05	195	41	4	6eb123cbea7bcadbdef086a8c230f0a73caf4930
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GATA2 ELN PTPRG KLF4	3.06e-05	195	41	4	75db19c0371320ea5fce1d6de8c1b40b1e6a2e58
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MPDZ HIC1 PTPRG SHANK3	3.06e-05	195	41	4	22a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU3F1 KRT17 KLF4 HSPA1A	3.06e-05	195	41	4	66caa5c063184e7d3d653c8f6c289555cb36fa82
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU3F1 KRT17 KLF4 HSPA1A	3.06e-05	195	41	4	ed74c113074fb5d3c42f2330b0e6042d32c3611a
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GATA2 SLCO4A1 KLF4 SHANK3	3.12e-05	196	41	4	915e4a7422058be246b54760df31e8a607310625
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	POU3F1 SARAF HSPA1A MN1	3.12e-05	196	41	4	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	Severe-CD4+_T\|Severe / Disease group and Cell class	PHF1 SARAF RARG PIM1	3.12e-05	196	41	4	576e0aa2ae146a86201dea21097ffe1c867956e7
ToppCell	critical-Epithelial-Squamous\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SLCO4A1 KRT16 KRT17 PIM1	3.18e-05	197	41	4	cfbdaada7169afb68455724ae87032ff311b2d89
ToppCell	CV-Severe-0\|Severe / Virus stimulation, Condition and Cluster	HGSNAT SARAF RARG NFKB2	3.18e-05	197	41	4	d13fc20b31ab6d9117437fba319c72f3a552858f
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HIC1 KLF4 HSPA1A NFKB2	3.18e-05	197	41	4	0c8650bde08e1317baee4793201645d86f16e15d
ToppCell	moderate-Epithelial-Squamous\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SLCO4A1 KRT16 KRT17 PIM1	3.18e-05	197	41	4	2e13881f917d4f62a5b3e968e41c57e43300d988
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GATA2 SLCO4A1 KLF4 SHANK3	3.18e-05	197	41	4	81718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FZD8 RARG MN1 EBF4	3.18e-05	197	41	4	3fe665c0277d091290b63f0dd24c0c6536a45309
ToppCell	Control_saline-Endothelial-Endothelial-Activated_Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	GATA2 HIC1 KLF4 HSPA1B	3.24e-05	198	41	4	3c3a5d2555f6af4aa33f9ea778808315d0e39d86
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GATA2 SLCO4A1 KLF4 SHANK3	3.24e-05	198	41	4	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRG KLF4 HSPA1A SHANK3	3.24e-05	198	41	4	31ba87552be97c9b78c9e82f98e96699ccb19824
ToppCell	Endothelial_cells\|World / lung cells shred on cell class, cell subclass, sample id	GATA2 SLCO4A1 ELN SHANK3	3.24e-05	198	41	4	b93effa428ec036542fa21647dfef9589c64640f
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	HIC1 SARAF HSPA1A HSPA1B	3.24e-05	198	41	4	a1c8e5c332336823c47c04e56b6d7bc8f057c9da
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HIC1 IDH3G KLF4 MN1	3.24e-05	198	41	4	c26c909e95225440abdf558b1b858ffc06177000
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRG KLF4 HSPA1A SHANK3	3.24e-05	198	41	4	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRG KLF4 HSPA1A SHANK3	3.24e-05	198	41	4	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GATA2 SLCO4A1 KLF4 SHANK3	3.24e-05	198	41	4	a1ccbf0e653b2dd665c2254920eb9b37243cc0bd
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KLF4 HSPA1A HSPA1B	1.19e-04	50	21	3	GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_STRESS
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KLF4 HSPA1A HSPA1B	1.19e-04	50	21	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_5_STRESS
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KLF4 HSPA1A HSPA1B	1.19e-04	50	21	3	GAVISH_3CA_METAPROGRAM_MACROPHAGES_STRESS_HSP
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KLF4 HSPA1A HSPA1B	1.19e-04	50	21	3	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_STRESS
Computational	Developmental processes.	POU3F1 RARG KRT16 KRT17 PTPRG	3.74e-04	333	21	5	MODULE_220
Computational	Keratin.	KRT16 KRT17	1.15e-03	26	21	2	MODULE_298
Computational	Genes in the cancer module 68.	KRT16 KRT17	1.15e-03	26	21	2	MODULE_68
Computational	Genes in the cancer module 153.	KRT16 KRT17	1.96e-03	34	21	2	MODULE_153
Computational	Genes upregulated in subsets of cells of a given type within various tumors	GATA2 PIM1	4.05e-03	49	21	2	GAVISH_3CA_MALIGNANT_METAPROGRAM_34_PLATELET_ACTIVATION
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSPA1A HSPA1B	4.21e-03	50	21	2	GAVISH_3CA_METAPROGRAM_CD4_T_CELLS_STRESS_HSP
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT16 KRT17	4.21e-03	50	21	2	GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPI3
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSPA1A HSPA1B	4.21e-03	50	21	2	GAVISH_3CA_METAPROGRAM_B_CELLS_HSP_STRESS
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT16 KRT17	4.21e-03	50	21	2	GAVISH_3CA_MALIGNANT_METAPROGRAM_40_PDAC_RELATED
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT17 KLF4	4.21e-03	50	21	2	GAVISH_3CA_METAPROGRAM_EPITHELIAL_STRESS
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSPA1A HSPA1B	4.21e-03	50	21	2	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_HEAT_SHOCK
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT16 KRT17	4.21e-03	50	21	2	GAVISH_3CA_MALIGNANT_METAPROGRAM_19_EPITHELIAL_SENESCENCE
Computational	Genes in the cancer module 322.	PTPRG PDK2	5.82e-03	59	21	2	MODULE_322
Computational	Immune / stress response genes.	GATA2 POU3F1 ELN KLF4	5.87e-03	383	21	4	MODULE_33
Disease	Pachyonychia congenita syndrome	KRT16 KRT17	1.13e-05	4	41	2	cv:C0265334
Disease	Pachyonychia Congenita, Type 2 (disorder)	KRT16 KRT17	1.13e-05	4	41	2	C1721007
Disease	Pachyonychia Congenita, Jadassohn Lewandowsky Type	KRT16 KRT17	1.13e-05	4	41	2	C1706595
Disease	pachyonychia congenita (is_implicated_in)	KRT16 KRT17	1.13e-05	4	41	2	DOID:0050449 (is_implicated_in)
Disease	Pachyonychia Congenita	KRT16 KRT17	1.88e-05	5	41	2	C0265334
Disease	graft-versus-host disease (biomarker_via_orthology)	HSPA1A HSPA1B	1.88e-05	5	41	2	DOID:0081267 (biomarker_via_orthology)
Disease	ectodermal dysplasia (is_implicated_in)	KRT16 KRT17	3.94e-05	7	41	2	DOID:2121 (is_implicated_in)
Disease	Major depression, single episode	HSPA1A HSPA1B	6.74e-05	9	41	2	C0024517
Disease	myeloid leukemia (is_implicated_in)	GATA2 MN1	1.46e-04	13	41	2	DOID:8692 (is_implicated_in)
Disease	Muscular Dystrophy, Facioscapulohumeral	ELN HSPA1B	1.46e-04	13	41	2	C0238288
Disease	Carcinoma, Pancreatic Ductal	HSPA1A HSPA1B	5.10e-04	24	41	2	C0887833
Disease	complement C4b measurement	HSPA1A HSPA1B	5.54e-04	25	41	2	EFO_0008092
Disease	Acute Myeloid Leukemia, M1	GATA2 GAS2L1 MN1	7.03e-04	125	41	3	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	GATA2 GAS2L1 MN1	7.03e-04	125	41	3	C1879321
Disease	human papilloma virus infection, oral cavity cancer	SLCO4A1 HSPA1A	1.57e-03	42	41	2	EFO_0001668, EFO_0005570
Disease	Leukemia, Myelocytic, Acute	GATA2 GAS2L1 MN1	1.79e-03	173	41	3	C0023467
Disease	Myocardial Ischemia	ELN KLF4 HSPA1A	1.88e-03	176	41	3	C0151744

Protein segments in the cluster

Peptide	Gene	Start	Entry
LAGLGFGGGGISSFP	PTPRG	516	P23470
GLGYGLLGDGIGYVL	ADCY8	261	P40145
AGALGPGSGYPGAGF	RARG	11	P13631
GVAPGGTGGGLLYGR	KLF4	161	O43474
CHLRGGGGGGGGYAP	HIC1	156	Q14526
GYEPGDLGAVGGGPL	FOXI2	26	Q6ZQN5
IISGLYQGAGGPGPG	HSPA1B	606	P0DMV9
GGGGSYLFSLLLGGD	SLC10A3	266	P09131
QYLPRGPGGGAGGTG	POU3F1	6	Q03052
VYAPGELGPGGGGAS	POU3F1	411	Q03052
YGGGLGAGFGGGLGA	KRT16	86	P08779
PGTGGTPLAGFGYGL	PDK2	316	Q15119
GLGTGLGTGLGFGGF	NUP54	76	Q7Z3B4
GPLSVYPGAGGGSGG	GATA2	136	P23769
GAGGPGGRGEYEELG	FZD8	366	Q9H461
GLVGGPGLVAGANYG	IDH3G	286	P51553
GSGGMGYPRLGGEGG	GTPBP10	26	A4D1E9
GGGYGSSFGGVDGLL	KRT17	66	Q04695
GDLGYGLGRKPGGIY	CCDC125	26	Q86Z20
QQSGYGGGLGAGLGG	EBF4	471	Q9BQW3
AGLGGYGAPGVAGLG	EBF4	481	Q9BQW3
YGLGLPGGGDGFLTG	GAS2L1	41	Q99501
GLIEGYGGRGKGGLP	GALNT17	86	Q6IS24
GYLGPGGIGDFGKYP	HGSNAT	446	Q68CP4
IISGLYQGAGGPGPG	HSPA1A	606	P0DMV8
GVPGGVFYPGAGLGA	ELN	36	P15502
VFYPGAGLGALGGGA	ELN	41	P15502
YGAAAGLVPGGPGFG	ELN	316	P15502
LAGLGGGFGYVVGGI	SLC45A1	271	Q9Y2W3
GRLLGYGGAAGGLGS	MN1	131	Q10571
LSPGTGGGVRGGVGY	PHF1	521	O43189
GPLLGSGGFGSVYSG	PIM1	41	P11309
LYGFRKVVLGGPGGG	HSF5	86	Q4G112
LGGYAKLGGGGDLGA	TMEM200B	291	Q69YZ2
GLGTGGILGYLFGSN	SARAF	266	Q96BY9
DGSVLPFLGGLGGGY	SLC22A23	81	A1A5C7
GLGYEGLGLGIGLRG	SETD1B	941	Q9UPS6
GGAGGGGGGYRPIIQ	PRR12	371	Q9ULL5
PGGGGGYLFALLLDG	SLC10A5	216	Q5PT55
GYLVVPAGGGGTFLG	SLCO4A1	426	Q96BD0
GLGFSIVGGYGSPHG	MPDZ	1996	O75970
LYKAAGGGGPLYGDG	SRCIN1	451	Q9C0H9
GLDYGAGDGPGLAFG	SHANK3	996	Q9BYB0
LGATGLGHFGYGRGP	SSC4D	391	Q8WTU2
GYGGAGGGGSLGFFP	NFKB2	366	Q00653