| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | steroid 11-beta-monooxygenase activity | 2.33e-06 | 2 | 31 | 2 | GO:0004507 | |
| GeneOntologyMolecularFunction | corticosterone 18-monooxygenase activity | 2.33e-06 | 2 | 31 | 2 | GO:0047783 | |
| GeneOntologyMolecularFunction | G protein-coupled amine receptor activity | 3.47e-05 | 41 | 31 | 3 | GO:0008227 | |
| GeneOntologyMolecularFunction | adrenergic receptor activity | 1.04e-04 | 10 | 31 | 2 | GO:0004935 | |
| GeneOntologyMolecularFunction | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen | 1.80e-04 | 13 | 31 | 2 | GO:0016713 | |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | 3.37e-04 | 884 | 31 | 7 | GO:0004930 | |
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity | 7.41e-04 | 26 | 31 | 2 | GO:0005248 | |
| GeneOntologyMolecularFunction | transforming growth factor beta receptor binding | 1.05e-03 | 31 | 31 | 2 | GO:0005160 | |
| GeneOntologyMolecularFunction | steroid binding | 1.13e-03 | 133 | 31 | 3 | GO:0005496 | |
| GeneOntologyMolecularFunction | steroid hydroxylase activity | 1.27e-03 | 34 | 31 | 2 | GO:0008395 | |
| GeneOntologyMolecularFunction | tetrapyrrole binding | 2.07e-03 | 164 | 31 | 3 | GO:0046906 | |
| GeneOntologyMolecularFunction | sodium channel activity | 2.95e-03 | 52 | 31 | 2 | GO:0005272 | |
| GeneOntologyMolecularFunction | transmembrane signaling receptor activity | 4.02e-03 | 1353 | 31 | 7 | GO:0004888 | |
| GeneOntologyBiologicalProcess | positive regulation of blood pressure | 2.04e-06 | 59 | 32 | 4 | GO:0045777 | |
| GeneOntologyBiologicalProcess | regulation of systemic arterial blood pressure mediated by a chemical signal | 2.34e-06 | 61 | 32 | 4 | GO:0003044 | |
| GeneOntologyBiologicalProcess | regulation of blood volume by renal aldosterone | 1.40e-05 | 4 | 32 | 2 | GO:0002017 | |
| GeneOntologyBiologicalProcess | olefinic compound biosynthetic process | 2.15e-05 | 35 | 32 | 3 | GO:0120255 | |
| GeneOntologyBiologicalProcess | regulation of systemic arterial blood pressure | 3.93e-05 | 124 | 32 | 4 | GO:0003073 | |
| GeneOntologyBiologicalProcess | positive regulation of blood pressure by epinephrine-norepinephrine | 4.87e-05 | 7 | 32 | 2 | GO:0003321 | |
| GeneOntologyBiologicalProcess | regulation of systemic arterial blood pressure by norepinephrine-epinephrine | 6.49e-05 | 8 | 32 | 2 | GO:0001993 | |
| GeneOntologyBiologicalProcess | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 7.33e-05 | 286 | 32 | 5 | GO:0007188 | |
| GeneOntologyBiologicalProcess | ketone biosynthetic process | 9.38e-05 | 57 | 32 | 3 | GO:0042181 | |
| GeneOntologyBiologicalProcess | cortisol biosynthetic process | 1.04e-04 | 10 | 32 | 2 | GO:0034651 | |
| GeneOntologyBiologicalProcess | tertiary alcohol biosynthetic process | 1.04e-04 | 10 | 32 | 2 | GO:1902645 | |
| GeneOntologyBiologicalProcess | cellular response to nitrogen compound | 1.26e-04 | 752 | 32 | 7 | GO:1901699 | |
| GeneOntologyBiologicalProcess | aldosterone biosynthetic process | 1.27e-04 | 11 | 32 | 2 | GO:0032342 | |
| GeneOntologyBiologicalProcess | cellular response to hypoxia | 1.31e-04 | 169 | 32 | 4 | GO:0071456 | |
| GeneOntologyBiologicalProcess | cortisol metabolic process | 1.52e-04 | 12 | 32 | 2 | GO:0034650 | |
| GeneOntologyBiologicalProcess | cellular response to decreased oxygen levels | 1.60e-04 | 178 | 32 | 4 | GO:0036294 | |
| GeneOntologyBiologicalProcess | mineralocorticoid biosynthetic process | 1.80e-04 | 13 | 32 | 2 | GO:0006705 | |
| GeneOntologyBiologicalProcess | primary alcohol biosynthetic process | 2.10e-04 | 14 | 32 | 2 | GO:0034309 | |
| GeneOntologyBiologicalProcess | aldosterone metabolic process | 2.10e-04 | 14 | 32 | 2 | GO:0032341 | |
| GeneOntologyBiologicalProcess | cellular response to oxygen levels | 2.26e-04 | 195 | 32 | 4 | GO:0071453 | |
| GeneOntologyBiologicalProcess | mineralocorticoid metabolic process | 3.13e-04 | 17 | 32 | 2 | GO:0008212 | |
| GeneOntologyBiologicalProcess | drinking behavior | 3.51e-04 | 18 | 32 | 2 | GO:0042756 | |
| GeneOntologyBiologicalProcess | renal system process involved in regulation of blood volume | 3.51e-04 | 18 | 32 | 2 | GO:0001977 | |
| GeneOntologyBiologicalProcess | glucocorticoid biosynthetic process | 3.51e-04 | 18 | 32 | 2 | GO:0006704 | |
| GeneOntologyBiologicalProcess | blood circulation | 4.24e-04 | 648 | 32 | 6 | GO:0008015 | |
| GeneOntologyBiologicalProcess | positive regulation of transcription by RNA polymerase III | 4.35e-04 | 20 | 32 | 2 | GO:0045945 | |
| GeneOntologyBiologicalProcess | regulation of blood pressure | 4.75e-04 | 237 | 32 | 4 | GO:0008217 | |
| GeneOntologyBiologicalProcess | tertiary alcohol metabolic process | 5.28e-04 | 22 | 32 | 2 | GO:1902644 | |
| GeneOntologyBiologicalProcess | response to nitrogen compound | 5.68e-04 | 1272 | 32 | 8 | GO:1901698 | |
| GeneOntologyBiologicalProcess | regulation of systemic arterial blood pressure by circulatory renin-angiotensin | 5.78e-04 | 23 | 32 | 2 | GO:0001991 | |
| GeneOntologyBiologicalProcess | adenylate cyclase-activating adrenergic receptor signaling pathway | 6.84e-04 | 25 | 32 | 2 | GO:0071880 | |
| GeneOntologyBiologicalProcess | C21-steroid hormone biosynthetic process | 7.40e-04 | 26 | 32 | 2 | GO:0006700 | |
| GeneOntologyBiologicalProcess | glucocorticoid metabolic process | 7.99e-04 | 27 | 32 | 2 | GO:0008211 | |
| GeneOntologyBiologicalProcess | circulatory system process | 8.11e-04 | 733 | 32 | 6 | GO:0003013 | |
| GeneOntologyBiologicalProcess | positive regulation of systemic arterial blood pressure | 8.60e-04 | 28 | 32 | 2 | GO:0003084 | |
| GeneOntologyBiologicalProcess | response to abiotic stimulus | 8.88e-04 | 1361 | 32 | 8 | GO:0009628 | |
| GeneOntologyBiologicalProcess | endocrine process | 9.05e-04 | 123 | 32 | 3 | GO:0050886 | |
| GeneOntologyBiologicalProcess | aldehyde biosynthetic process | 1.05e-03 | 31 | 32 | 2 | GO:0046184 | |
| GeneOntologyBiologicalProcess | renal system process involved in regulation of systemic arterial blood pressure | 1.05e-03 | 31 | 32 | 2 | GO:0003071 | |
| GeneOntologyBiologicalProcess | heart contraction | 1.12e-03 | 298 | 32 | 4 | GO:0060047 | |
| GeneOntologyBiologicalProcess | negative regulation of systemic arterial blood pressure | 1.12e-03 | 32 | 32 | 2 | GO:0003085 | |
| GeneOntologyBiologicalProcess | regulation of transcription by RNA polymerase III | 1.12e-03 | 32 | 32 | 2 | GO:0006359 | |
| GeneOntologyBiologicalProcess | heart process | 1.28e-03 | 309 | 32 | 4 | GO:0003015 | |
| GeneOntologyBiologicalProcess | adrenergic receptor signaling pathway | 1.34e-03 | 35 | 32 | 2 | GO:0071875 | |
| GeneOntologyBiologicalProcess | membrane depolarization during action potential | 1.42e-03 | 36 | 32 | 2 | GO:0086010 | |
| GeneOntologyBiologicalProcess | regulation of systemic arterial blood pressure by renin-angiotensin | 1.50e-03 | 37 | 32 | 2 | GO:0003081 | |
| GeneOntologyBiologicalProcess | renal system process | 1.57e-03 | 149 | 32 | 3 | GO:0003014 | |
| GeneOntologyBiologicalProcess | cellular response to angiotensin | 1.75e-03 | 40 | 32 | 2 | GO:1904385 | |
| GeneOntologyCellularComponent | voltage-gated sodium channel complex | 3.04e-04 | 17 | 32 | 2 | GO:0001518 | |
| GeneOntologyCellularComponent | sodium channel complex | 8.98e-04 | 29 | 32 | 2 | GO:0034706 | |
| GeneOntologyCellularComponent | dendrite | 1.70e-03 | 858 | 32 | 6 | GO:0030425 | |
| GeneOntologyCellularComponent | dendritic tree | 1.73e-03 | 860 | 32 | 6 | GO:0097447 | |
| GeneOntologyCellularComponent | somatodendritic compartment | 2.18e-03 | 1228 | 32 | 7 | GO:0036477 | |
| GeneOntologyCellularComponent | endoplasmic reticulum membrane | 2.92e-03 | 1293 | 32 | 7 | GO:0005789 | |
| GeneOntologyCellularComponent | endoplasmic reticulum subcompartment | 3.00e-03 | 1299 | 32 | 7 | GO:0098827 | |
| GeneOntologyCellularComponent | nuclear outer membrane-endoplasmic reticulum membrane network | 3.38e-03 | 1327 | 32 | 7 | GO:0042175 | |
| GeneOntologyCellularComponent | organelle membrane contact site | 3.44e-03 | 57 | 32 | 2 | GO:0044232 | |
| HumanPheno | Adrenocortical adenoma | 8.33e-07 | 9 | 12 | 3 | HP:0008256 | |
| HumanPheno | Secretory adrenocortical adenoma | 1.52e-05 | 3 | 12 | 2 | HP:0011746 | |
| HumanPheno | Neoplasm of the adrenal cortex | 3.17e-05 | 28 | 12 | 3 | HP:0100641 | |
| HumanPheno | Dexamethasone-suppressible primary hyperaldosteronism | 5.07e-05 | 5 | 12 | 2 | HP:0011739 | |
| HumanPheno | Nausea | 5.90e-05 | 99 | 12 | 4 | HP:0002018 | |
| HumanPheno | Limitation of knee mobility | 6.27e-05 | 35 | 12 | 3 | HP:0010501 | |
| HumanPheno | Neoplasm of the adrenal gland | 1.53e-04 | 47 | 12 | 3 | HP:0100631 | |
| HumanPheno | Elevated serum 11-deoxycortisol | 1.81e-04 | 9 | 12 | 2 | HP:0025436 | |
| HumanPheno | Primary hyperaldosteronism | 2.27e-04 | 10 | 12 | 2 | HP:0011736 | |
| HumanPheno | Pes valgus | 2.58e-04 | 56 | 12 | 3 | HP:0008081 | |
| MousePheno | abnormal urine progesterone level | 3.33e-06 | 2 | 26 | 2 | MP:0011545 | |
| MousePheno | abnormal urine deoxycorticosterone level | 3.33e-06 | 2 | 26 | 2 | MP:0011552 | |
| MousePheno | decreased urine corticosterone level | 3.33e-06 | 2 | 26 | 2 | MP:0011550 | |
| MousePheno | increased urine deoxycorticosterone level | 3.33e-06 | 2 | 26 | 2 | MP:0011553 | |
| MousePheno | increased urine progesterone level | 3.33e-06 | 2 | 26 | 2 | MP:0011546 | |
| MousePheno | hypotension | 1.81e-05 | 28 | 26 | 3 | MP:0001596 | |
| MousePheno | abnormal adrenal gland zona glomerulosa morphology | 1.99e-05 | 4 | 26 | 2 | MP:0008293 | |
| MousePheno | decreased urine aldosterone level | 1.99e-05 | 4 | 26 | 2 | MP:0011541 | |
| MousePheno | abnormal urine aldosterone level | 1.99e-05 | 4 | 26 | 2 | MP:0011539 | |
| MousePheno | abnormal urine corticosterone level | 1.99e-05 | 4 | 26 | 2 | MP:0011548 | |
| MousePheno | decreased urine hormone level | 1.99e-05 | 4 | 26 | 2 | MP:0014459 | |
| MousePheno | increased adrenal gland zona fasciculata size | 3.32e-05 | 5 | 26 | 2 | MP:0014286 | |
| MousePheno | decreased systemic arterial blood pressure | 3.81e-05 | 104 | 26 | 4 | MP:0002843 | |
| MousePheno | uterus adenomyosis | 4.97e-05 | 6 | 26 | 2 | MP:0009221 | |
| MousePheno | increased urine hormone level | 4.97e-05 | 6 | 26 | 2 | MP:0014458 | |
| MousePheno | adrenal gland hyperplasia | 4.97e-05 | 6 | 26 | 2 | MP:0009078 | |
| MousePheno | abnormal urine hormone level | 6.95e-05 | 7 | 26 | 2 | MP:0011538 | |
| MousePheno | pituitary gland hyperplasia | 6.95e-05 | 7 | 26 | 2 | MP:0000635 | |
| MousePheno | increased circulating angiotensin II level | 9.25e-05 | 8 | 26 | 2 | MP:0031232 | |
| MousePheno | increased angiotensin II level | 9.25e-05 | 8 | 26 | 2 | MP:0031229 | |
| MousePheno | abnormal progesterone level | 1.33e-04 | 54 | 26 | 3 | MP:0011384 | |
| MousePheno | decreased circulating renin level | 1.48e-04 | 10 | 26 | 2 | MP:0003353 | |
| MousePheno | delayed cellular replicative senescence | 1.48e-04 | 10 | 26 | 2 | MP:0008009 | |
| MousePheno | abnormal adrenocortical cell morphology | 1.48e-04 | 10 | 26 | 2 | MP:0008291 | |
| MousePheno | abnormal adrenal gland zona fasciculata size | 1.81e-04 | 11 | 26 | 2 | MP:0014284 | |
| MousePheno | uterus cyst | 1.81e-04 | 11 | 26 | 2 | MP:0009082 | |
| MousePheno | abnormal circulating angiotensin II level | 2.17e-04 | 12 | 26 | 2 | MP:0031230 | |
| MousePheno | abnormal angiotensin II level | 2.17e-04 | 12 | 26 | 2 | MP:0031227 | |
| MousePheno | hypokalemia | 2.17e-04 | 12 | 26 | 2 | MP:0004119 | |
| MousePheno | enlarged pituitary gland | 2.17e-04 | 12 | 26 | 2 | MP:0000636 | |
| MousePheno | decreased a-wave amplitude | 2.53e-04 | 67 | 26 | 3 | MP:0012143 | |
| MousePheno | abnormal a-wave amplitude | 2.76e-04 | 69 | 26 | 3 | MP:0012030 | |
| MousePheno | abnormal a-wave shape | 2.88e-04 | 70 | 26 | 3 | MP:0012034 | |
| MousePheno | increased renin activity | 2.99e-04 | 14 | 26 | 2 | MP:0005582 | |
| MousePheno | decreased circulating mineralocorticoid level | 2.99e-04 | 14 | 26 | 2 | MP:0003374 | |
| MousePheno | increased urine osmolality | 2.99e-04 | 14 | 26 | 2 | MP:0008055 | |
| MousePheno | increased circulating adrenocorticotropin level | 2.99e-04 | 14 | 26 | 2 | MP:0001748 | |
| MousePheno | decreased circulating aldosterone level | 2.99e-04 | 14 | 26 | 2 | MP:0002667 | |
| MousePheno | endometrium hyperplasia | 2.99e-04 | 14 | 26 | 2 | MP:0009092 | |
| MousePheno | decreased b-wave amplitude | 4.59e-04 | 82 | 26 | 3 | MP:0012144 | |
| MousePheno | abnormal b-wave shape | 5.10e-04 | 85 | 26 | 3 | MP:0012035 | |
| MousePheno | abnormal b-wave amplitude | 5.10e-04 | 85 | 26 | 3 | MP:0012031 | |
| MousePheno | abnormal adrenal gland zona fasciculata morphology | 5.58e-04 | 19 | 26 | 2 | MP:0008294 | |
| MousePheno | abnormal renin activity | 6.19e-04 | 20 | 26 | 2 | MP:0005581 | |
| MousePheno | abnormal skeletal muscle size | 6.63e-04 | 93 | 26 | 3 | MP:0009458 | |
| MousePheno | increased adrenocorticotropin level | 7.51e-04 | 22 | 26 | 2 | MP:0005129 | |
| MousePheno | abnormal muscle fiber morphology | 8.01e-04 | 406 | 26 | 5 | MP:0004087 | |
| MousePheno | increased circulating renin level | 8.22e-04 | 23 | 26 | 2 | MP:0003352 | |
| MousePheno | oliguria | 8.95e-04 | 24 | 26 | 2 | MP:0003620 | |
| MousePheno | abnormal electroretinogram waveform feature | 9.71e-04 | 106 | 26 | 3 | MP:0012029 | |
| MousePheno | abnormal systemic arterial blood pressure | 1.02e-03 | 245 | 26 | 4 | MP:0000230 | |
| MousePheno | increased circulating pituitary hormone level | 1.08e-03 | 110 | 26 | 3 | MP:0005117 | |
| MousePheno | abnormal circulating renin level | 1.31e-03 | 29 | 26 | 2 | MP:0003349 | |
| MousePheno | decreased circulating enzyme level | 1.32e-03 | 263 | 26 | 4 | MP:0014451 | |
| MousePheno | increased pituitary hormone level | 1.67e-03 | 128 | 26 | 3 | MP:0003973 | |
| MousePheno | decreased urine output | 1.70e-03 | 33 | 26 | 2 | MP:0031358 | |
| MousePheno | decreased enzyme/conezyme level | 1.75e-03 | 284 | 26 | 4 | MP:0014449 | |
| MousePheno | enlarged adrenal glands | 1.80e-03 | 34 | 26 | 2 | MP:0000642 | |
| MousePheno | decreased thymus weight | 2.02e-03 | 36 | 26 | 2 | MP:0004956 | |
| MousePheno | increased skeletal muscle fiber size | 2.02e-03 | 36 | 26 | 2 | MP:0009399 | |
| MousePheno | abnormal skeletal muscle fiber size | 2.16e-03 | 140 | 26 | 3 | MP:0009398 | |
| MousePheno | abnormal circulating aldosterone level | 2.24e-03 | 38 | 26 | 2 | MP:0005346 | |
| MousePheno | abnormal circulating mineralocorticoid level | 2.24e-03 | 38 | 26 | 2 | MP:0003372 | |
| MousePheno | abnormal skeletal muscle mass | 2.58e-03 | 149 | 26 | 3 | MP:0004817 | |
| MousePheno | abnormal aldosterone level | 2.61e-03 | 41 | 26 | 2 | MP:0011415 | |
| MousePheno | decreased fluid intake | 2.61e-03 | 41 | 26 | 2 | MP:0011942 | |
| MousePheno | abnormal adrenocorticotropin level | 2.61e-03 | 41 | 26 | 2 | MP:0003966 | |
| MousePheno | abnormal adrenal cortex morphology | 2.74e-03 | 42 | 26 | 2 | MP:0008288 | |
| MousePheno | abnormal pituitary gland size | 2.74e-03 | 42 | 26 | 2 | MP:0008936 | |
| MousePheno | increased variability of skeletal muscle fiber size | 2.87e-03 | 43 | 26 | 2 | MP:0009403 | |
| MousePheno | decreased circulating corticosterone level | 2.87e-03 | 43 | 26 | 2 | MP:0002665 | |
| MousePheno | decreased circulating glucocorticoid level | 3.00e-03 | 44 | 26 | 2 | MP:0003368 | |
| MousePheno | increased brain weight | 3.00e-03 | 44 | 26 | 2 | MP:0002176 | |
| MousePheno | increased systemic arterial blood pressure | 3.04e-03 | 158 | 26 | 3 | MP:0002842 | |
| MousePheno | abnormal muscle morphology | 3.29e-03 | 1106 | 26 | 7 | MP:0002108 | |
| MousePheno | abnormal endometrium morphology | 3.71e-03 | 49 | 26 | 2 | MP:0004896 | |
| MousePheno | abnormal circulating pituitary hormone level | 3.87e-03 | 172 | 26 | 3 | MP:0005116 | |
| MousePheno | increased circulating glucocorticoid level | 4.01e-03 | 51 | 26 | 2 | MP:0003367 | |
| MousePheno | increased circulating corticosterone level | 4.01e-03 | 51 | 26 | 2 | MP:0001745 | |
| MousePheno | increased myocardial fiber size | 4.32e-03 | 53 | 26 | 2 | MP:0004564 | |
| MousePheno | decreased urine osmolality | 4.49e-03 | 54 | 26 | 2 | MP:0002988 | |
| MousePheno | decreased circulating potassium level | 4.49e-03 | 54 | 26 | 2 | MP:0005628 | |
| MousePheno | skeletal muscle atrophy | 4.49e-03 | 54 | 26 | 2 | MP:0009417 | |
| Domain | Cyt_P450_mitochondrial | 2.67e-06 | 2 | 31 | 2 | IPR002399 | |
| Domain | Na_channel_asu | 1.19e-04 | 10 | 31 | 2 | IPR001696 | |
| Domain | Na_trans_assoc | 1.19e-04 | 10 | 31 | 2 | IPR010526 | |
| Domain | ADR_fam | 1.19e-04 | 10 | 31 | 2 | IPR002233 | |
| Domain | Na_trans_assoc | 1.19e-04 | 10 | 31 | 2 | PF06512 | |
| Domain | Cyt_P450_CS | 3.49e-03 | 53 | 31 | 2 | IPR017972 | |
| Domain | CYTOCHROME_P450 | 4.02e-03 | 57 | 31 | 2 | PS00086 | |
| Domain | Channel_four-helix_dom | 4.02e-03 | 57 | 31 | 2 | IPR027359 | |
| Domain | - | 4.02e-03 | 57 | 31 | 2 | 1.20.120.350 | |
| Domain | - | 4.16e-03 | 58 | 31 | 2 | 1.10.630.10 | |
| Domain | p450 | 4.16e-03 | 58 | 31 | 2 | PF00067 | |
| Domain | Cyt_P450 | 4.44e-03 | 60 | 31 | 2 | IPR001128 | |
| Domain | GPCR_Rhodpsn_7TM | 4.59e-03 | 670 | 31 | 5 | IPR017452 | |
| Domain | 7tm_1 | 4.79e-03 | 677 | 31 | 5 | PF00001 | |
| Domain | G_PROTEIN_RECEP_F1_1 | 5.03e-03 | 685 | 31 | 5 | PS00237 | |
| Domain | G_PROTEIN_RECEP_F1_2 | 5.22e-03 | 691 | 31 | 5 | PS50262 | |
| Domain | GPCR_Rhodpsn | 5.26e-03 | 692 | 31 | 5 | IPR000276 | |
| Domain | IQ | 6.17e-03 | 71 | 31 | 2 | PF00612 | |
| Domain | IQ | 7.96e-03 | 81 | 31 | 2 | SM00015 | |
| Domain | IQ_motif_EF-hand-BS | 9.75e-03 | 90 | 31 | 2 | IPR000048 | |
| Domain | IQ | 1.04e-02 | 93 | 31 | 2 | PS50096 | |
| Domain | 7TM_GPCR_Srsx | 1.48e-02 | 112 | 31 | 2 | SM01381 | |
| Domain | Ion_trans_dom | 1.53e-02 | 114 | 31 | 2 | IPR005821 | |
| Pathway | WP_ADHD_AND_AUTISM_ASD_PATHWAYS | 4.34e-06 | 367 | 27 | 7 | M48346 | |
| Pathway | WP_GPCRS_NONODORANT | 9.05e-06 | 266 | 27 | 6 | MM15843 | |
| Pathway | WP_GPCRS_OTHER | 2.77e-05 | 93 | 27 | 4 | M39629 | |
| Pathway | KEGG_MEDICUS_REFERENCE_STEROID_HORMONE_BIOSYNTHESIS_PROGESTERONE_TO_CORTISOL_CORTISONE | 3.52e-05 | 5 | 27 | 2 | M47522 | |
| Pathway | REACTOME_METABOLISM_OF_STEROID_HORMONES | 4.29e-05 | 36 | 27 | 3 | M27081 | |
| Pathway | REACTOME_METABOLISM_OF_STEROID_HORMONES | 6.36e-05 | 41 | 27 | 3 | MM14757 | |
| Pathway | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | 6.84e-05 | 42 | 27 | 3 | M5868 | |
| Pathway | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | 6.84e-05 | 42 | 27 | 3 | MM14971 | |
| Pathway | REACTOME_ADRENOCEPTORS | 1.26e-04 | 9 | 27 | 2 | M27302 | |
| Pathway | REACTOME_ADRENOCEPTORS | 1.26e-04 | 9 | 27 | 2 | MM15009 | |
| Pathway | KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION | 1.47e-04 | 272 | 27 | 5 | M13380 | |
| Pathway | REACTOME_GLUCOCORTICOID_BIOSYNTHESIS | 1.57e-04 | 10 | 27 | 2 | M27076 | |
| Pathway | REACTOME_GLUCOCORTICOID_BIOSYNTHESIS | 1.92e-04 | 11 | 27 | 2 | MM14750 | |
| Pathway | REACTOME_GPCR_LIGAND_BINDING | 2.00e-04 | 463 | 27 | 6 | M507 | |
| Pathway | REACTOME_MINERALOCORTICOID_BIOSYNTHESIS | 2.30e-04 | 12 | 27 | 2 | MM14749 | |
| Pathway | WP_GLUCOCORTICOID_BIOSYNTHESIS | 3.17e-04 | 14 | 27 | 2 | M46449 | |
| Pathway | WP_MINERALOCORTICOID_BIOSYNTHESIS | 3.17e-04 | 14 | 27 | 2 | M46453 | |
| Pathway | WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE | 4.17e-04 | 16 | 27 | 2 | M39849 | |
| Pathway | WP_CLASSICAL_PATHWAY_OF_STEROIDOGENESIS_WITH_GLUCOCORTICOID_AND_MINERALOCORTICOID_METABOLISM | 4.17e-04 | 16 | 27 | 2 | M39815 | |
| Pathway | REACTOME_ENDOGENOUS_STEROLS | 1.03e-03 | 25 | 27 | 2 | M11184 | |
| Pathway | REACTOME_GPCR_LIGAND_BINDING | 1.20e-03 | 430 | 27 | 5 | MM15160 | |
| Pathway | REACTOME_ENDOGENOUS_STEROLS | 1.20e-03 | 27 | 27 | 2 | MM14844 | |
| Pathway | REACTOME_DISEASES_OF_METABOLISM | 1.23e-03 | 250 | 27 | 4 | M27554 | |
| Pathway | WP_MONOAMINE_GPCRS | 1.59e-03 | 31 | 27 | 2 | MM15871 | |
| Pathway | REACTOME_SIGNALING_BY_BMP | 1.59e-03 | 31 | 27 | 2 | M1662 | |
| Pathway | REACTOME_SIGNALING_BY_BMP | 1.59e-03 | 31 | 27 | 2 | MM14789 | |
| Pathway | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 1.59e-03 | 31 | 27 | 2 | M877 | |
| Pathway | REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING | 1.63e-03 | 123 | 27 | 3 | MM14988 | |
| Pathway | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 1.69e-03 | 32 | 27 | 2 | M27455 | |
| Pathway | REACTOME_METABOLISM_OF_STEROIDS | 1.74e-03 | 126 | 27 | 3 | MM15553 | |
| Pathway | WP_MONOAMINE_GPCRS | 1.80e-03 | 33 | 27 | 2 | M39585 | |
| Pathway | REACTOME_SIGNALING_BY_GPCR | 1.80e-03 | 702 | 27 | 6 | M746 | |
| Pathway | REACTOME_METABOLIC_DISORDERS_OF_BIOLOGICAL_OXIDATION_ENZYMES | 1.91e-03 | 34 | 27 | 2 | M27461 | |
| Pathway | REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING | 2.65e-03 | 146 | 27 | 3 | M27288 | |
| Pathway | PID_BMP_PATHWAY | 2.90e-03 | 42 | 27 | 2 | M181 | |
| Pathway | WP_OXIDATION_BY_CYTOCHROME_P450 | 3.04e-03 | 43 | 27 | 2 | MM15873 | |
| Pathway | REACTOME_METABOLISM_OF_STEROIDS | 3.09e-03 | 154 | 27 | 3 | M27832 | |
| Pathway | REACTOME_CA2_PATHWAY | 3.32e-03 | 45 | 27 | 2 | MM15040 | |
| Pathway | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | 3.38e-03 | 330 | 27 | 4 | M18334 | |
| Pathway | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | 3.49e-03 | 333 | 27 | 4 | MM14963 | |
| Pubmed | 4.32e-07 | 16 | 33 | 3 | 37727456 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 17651452 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 23150505 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 34743356 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 35012455 | ||
| Pubmed | Role of genetic variation in regulation of aldosterone biosynthesis. | 8.73e-07 | 2 | 33 | 2 | 21164264 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 2783417 | ||
| Pubmed | Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism. | 8.73e-07 | 2 | 33 | 2 | 2256920 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 18079277 | ||
| Pubmed | Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism. | 8.73e-07 | 2 | 33 | 2 | 20339375 | |
| Pubmed | Editorial: polymorphisms in CYP11B genes and 11-hydroxylase activity. | 8.73e-07 | 2 | 33 | 2 | 15699546 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 18162527 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 38341019 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 20708777 | ||
| Pubmed | Molecular genetic studies on the biosynthesis of aldosterone in humans. | 8.73e-07 | 2 | 33 | 2 | 22217843 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 20808686 | ||
| Pubmed | Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation. | 8.73e-07 | 2 | 33 | 2 | 16396990 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 24837548 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 8645611 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 30046010 | ||
| Pubmed | Familial and phenotypic associations of the aldosterone Renin ratio. | 8.73e-07 | 2 | 33 | 2 | 19820005 | |
| Pubmed | [123 I]Iodometomidate for molecular imaging of adrenocortical cytochrome P450 family 11B enzymes. | 8.73e-07 | 2 | 33 | 2 | 18397978 | |
| Pubmed | Expression and localization of cytochrome P450(11beta,aldo) mRNA in the frog brain. | 8.73e-07 | 2 | 33 | 2 | 12231255 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 1518866 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 20634641 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 1303253 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 22622494 | ||
| Pubmed | Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets. | 8.73e-07 | 2 | 33 | 2 | 21519965 | |
| Pubmed | Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children. | 8.73e-07 | 2 | 33 | 2 | 21625068 | |
| Pubmed | Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18-hydroxycortisol production. | 8.73e-07 | 2 | 33 | 2 | 15062555 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 16110193 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 23761669 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 26066897 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 17075030 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 17075029 | ||
| Pubmed | Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta). | 8.73e-07 | 2 | 33 | 2 | 2592361 | |
| Pubmed | CYP11B2-CYP11B1 haplotypes associated with decreased 11 beta-hydroxylase activity. | 8.73e-07 | 2 | 33 | 2 | 15507509 | |
| Pubmed | Polymorphism of CYP11B2 determines salt sensitivity in Japanese. | 8.73e-07 | 2 | 33 | 2 | 17296872 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 23314847 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 17980006 | ||
| Pubmed | Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene. | 8.73e-07 | 2 | 33 | 2 | 16984984 | |
| Pubmed | Evidence for local aldosterone synthesis in the large intestine of the mouse. | 8.73e-07 | 2 | 33 | 2 | 35288482 | |
| Pubmed | Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice. | 8.73e-07 | 2 | 33 | 2 | 15731365 | |
| Pubmed | Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase. | 8.73e-07 | 2 | 33 | 2 | 18039983 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 1741400 | ||
| Pubmed | Cyp11b1 null mouse, a model of congenital adrenal hyperplasia. | 8.73e-07 | 2 | 33 | 2 | 19029289 | |
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 32540969 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 26047574 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 26324851 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 18651133 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 7669222 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 22083159 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 15522937 | ||
| Pubmed | 8.73e-07 | 2 | 33 | 2 | 22933298 | ||
| Pubmed | 2.24e-06 | 27 | 33 | 3 | 23471215 | ||
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 36861295 | ||
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 21467193 | ||
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 36778748 | ||
| Pubmed | Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain. | 2.62e-06 | 3 | 33 | 2 | 8111631 | |
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 2546938 | ||
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 16118390 | ||
| Pubmed | Interaction of CYP11B1 (cytochrome P-45011 beta) with CYP11A1 (cytochrome P-450scc) in COS-1 cells. | 2.62e-06 | 3 | 33 | 2 | 10411633 | |
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 18974272 | ||
| Pubmed | Control of renin secretion from kidneys with renin cell hyperplasia. | 2.62e-06 | 3 | 33 | 2 | 24285498 | |
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 7750493 | ||
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 17984374 | ||
| Pubmed | Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids. | 2.62e-06 | 3 | 33 | 2 | 1686470 | |
| Pubmed | Antiaging Gene Klotho Regulates Adrenal CYP11B2 Expression and Aldosterone Synthesis. | 2.62e-06 | 3 | 33 | 2 | 26471128 | |
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 2233742 | ||
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 33271253 | ||
| Pubmed | Mislocalization of protein kinase A drives pathology in Cushing's syndrome. | 2.62e-06 | 3 | 33 | 2 | 35830806 | |
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 28355486 | ||
| Pubmed | The prolactin regulatory element-binding regulates of the 11beta-hydroxylase gene. | 2.62e-06 | 3 | 33 | 2 | 18801336 | |
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 11932209 | ||
| Pubmed | Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes. | 2.62e-06 | 3 | 33 | 2 | 32245948 | |
| Pubmed | 2.62e-06 | 3 | 33 | 2 | 20038812 | ||
| Pubmed | Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus. | 5.23e-06 | 4 | 33 | 2 | 30917317 | |
| Pubmed | Adrenoceptor-related decrease in serum triglycerides is independent of PPARα activation. | 5.23e-06 | 4 | 33 | 2 | 31230416 | |
| Pubmed | Zona Glomerulosa-Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice. | 5.23e-06 | 4 | 33 | 2 | 38573585 | |
| Pubmed | Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation. | 5.23e-06 | 4 | 33 | 2 | 32320669 | |
| Pubmed | Adrenal Abcg1 Controls Cholesterol Flux and Steroidogenesis. | 5.23e-06 | 4 | 33 | 2 | 38301271 | |
| Pubmed | 5.23e-06 | 4 | 33 | 2 | 37102205 | ||
| Pubmed | 5.23e-06 | 4 | 33 | 2 | 11903322 | ||
| Pubmed | β-Catenin-Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer. | 5.23e-06 | 4 | 33 | 2 | 37129912 | |
| Pubmed | 5.23e-06 | 4 | 33 | 2 | 8372604 | ||
| Pubmed | 5.23e-06 | 4 | 33 | 2 | 19342457 | ||
| Pubmed | 5.23e-06 | 4 | 33 | 2 | 29440508 | ||
| Pubmed | 5.23e-06 | 4 | 33 | 2 | 23303406 | ||
| Pubmed | Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice. | 5.23e-06 | 4 | 33 | 2 | 32561853 | |
| Pubmed | CYP11B2 -344T/C gene polymorphism and blood pressure in patients with acromegaly. | 5.23e-06 | 4 | 33 | 2 | 17003099 | |
| Pubmed | 5.23e-06 | 4 | 33 | 2 | 26739946 | ||
| Pubmed | β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis. | 5.23e-06 | 4 | 33 | 2 | 32245949 | |
| Pubmed | Calcineurin regulates aldosterone production via dephosphorylation of NFATC4. | 5.23e-06 | 4 | 33 | 2 | 37310791 | |
| Pubmed | 8.72e-06 | 5 | 33 | 2 | 31398249 | ||
| Pubmed | 8.72e-06 | 5 | 33 | 2 | 7476975 | ||
| Pubmed | Adrenocortical zonation results from lineage conversion of differentiated zona glomerulosa cells. | 8.72e-06 | 5 | 33 | 2 | 24035414 | |
| Pubmed | The Adrenal Clock Prevents Aberrant Light-Induced Alterations in Circadian Glucocorticoid Rhythms. | 8.72e-06 | 5 | 33 | 2 | 30321360 | |
| Pubmed | Tissue kallikrein permits early renal adaptation to potassium load. | 8.72e-06 | 5 | 33 | 2 | 20624970 | |
| Pubmed | 8.72e-06 | 5 | 33 | 2 | 7590346 | ||
| Pubmed | 8.72e-06 | 5 | 33 | 2 | 12442007 | ||
| Interaction | GPRASP1 interactions | 3.74e-06 | 67 | 32 | 4 | int:GPRASP1 | |
| Interaction | CYP11B1 interactions | 2.44e-05 | 5 | 32 | 2 | int:CYP11B1 | |
| Interaction | AMFR interactions | 3.35e-05 | 237 | 32 | 5 | int:AMFR | |
| Interaction | SI interactions | 3.65e-05 | 6 | 32 | 2 | int:SI | |
| Interaction | CYP11B2 interactions | 1.09e-04 | 10 | 32 | 2 | int:CYP11B2 | |
| Cytoband | 17q23.3 | 2.15e-04 | 30 | 33 | 2 | 17q23.3 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr8q24 | 2.11e-03 | 355 | 33 | 3 | chr8q24 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr17q23 | 3.39e-03 | 120 | 33 | 2 | chr17q23 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr7p14 | 6.98e-03 | 174 | 33 | 2 | chr7p14 | |
| GeneFamily | Cytochrome P450 family 11 | 4.24e-06 | 3 | 22 | 2 | 1007 | |
| GeneFamily | Sodium voltage-gated channel alpha subunits | 5.06e-05 | 9 | 22 | 2 | 1203 | |
| GeneFamily | Adrenoceptors | 5.06e-05 | 9 | 22 | 2 | 169 | |
| Drug | dihydrochloride | 8.23e-08 | 159 | 32 | 6 | CID000070978 | |
| Drug | amitriptyline | 1.44e-06 | 140 | 32 | 5 | CID000002160 | |
| Drug | cyadox | 1.91e-06 | 2 | 32 | 2 | ctd:C020728 | |
| Drug | 18-hydroxydeoxycorticosterone | 1.91e-06 | 2 | 32 | 2 | ctd:C042509 | |
| Drug | synephrine | 2.03e-06 | 18 | 32 | 3 | CID000007172 | |
| Drug | sotalol | 3.27e-06 | 73 | 32 | 4 | CID000005253 | |
| Drug | 18-hydroxycortisol | 5.74e-06 | 3 | 32 | 2 | ctd:C033689 | |
| Drug | N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide | 5.74e-06 | 3 | 32 | 2 | ctd:C561228 | |
| Drug | dibenamine | 6.41e-06 | 26 | 32 | 3 | CID000005820 | |
| Drug | forskolin from Coleus forskohlii | 7.33e-06 | 1013 | 32 | 9 | CID000003413 | |
| Drug | (+,-)-Synephrine [94-07-5]; Down 200; 24uM; PC3; HT_HG-U133A | 7.68e-06 | 197 | 32 | 5 | 7150_DN | |
| Drug | tolazoline | 8.99e-06 | 29 | 32 | 3 | CID000005504 | |
| Drug | C05489 | 1.15e-05 | 4 | 32 | 2 | CID000440708 | |
| Drug | 4-(1H-imidazol-4-ylmethyl)piperidine | 1.15e-05 | 4 | 32 | 2 | ctd:C085755 | |
| Drug | Sparteinum | 1.19e-05 | 101 | 32 | 4 | CID000003966 | |
| Drug | 5-hydroxypropafenone | 1.47e-05 | 34 | 32 | 3 | CID000107927 | |
| Drug | 17alpha, 21-dihydroxypregnenolone | 1.91e-05 | 5 | 32 | 2 | CID000192735 | |
| Drug | tetradotoxin | 2.55e-05 | 428 | 32 | 6 | CID000020382 | |
| Drug | tripelennamine | 2.79e-05 | 42 | 32 | 3 | CID000005587 | |
| Drug | Br-pindolol | 2.86e-05 | 6 | 32 | 2 | CID000125847 | |
| Drug | Tetrahydronaphthalenes | 2.86e-05 | 6 | 32 | 2 | ctd:D013764 | |
| Drug | 2-fluoronorepinephrine | 2.86e-05 | 6 | 32 | 2 | CID000172745 | |
| Drug | Methandrostenolone | 2.86e-05 | 6 | 32 | 2 | ctd:D008696 | |
| Drug | Cortodoxone | 4.00e-05 | 7 | 32 | 2 | ctd:D003350 | |
| Drug | clenbuterol | 4.55e-05 | 142 | 32 | 4 | CID000002783 | |
| Drug | diisononyl phthalate | 4.73e-05 | 50 | 32 | 3 | ctd:C012125 | |
| Drug | salbutamol | 5.07e-05 | 146 | 32 | 4 | CID000002083 | |
| Drug | 2,2',3,3',4,6'-hexachlorobiphenyl | 5.33e-05 | 8 | 32 | 2 | ctd:C094859 | |
| Drug | Epinephrine | 5.33e-05 | 8 | 32 | 2 | DB00668 | |
| Drug | potassium | 5.84e-05 | 1008 | 32 | 8 | CID000000813 | |
| Drug | GKT137831 | 6.85e-05 | 9 | 32 | 2 | ctd:C576694 | |
| Drug | antazoline | 6.85e-05 | 9 | 32 | 2 | CID000002200 | |
| Drug | dapiprazole | 6.85e-05 | 9 | 32 | 2 | CID003033538 | |
| Drug | 2,2',3,4',5',6-hexachlorobiphenyl | 6.85e-05 | 9 | 32 | 2 | ctd:C120129 | |
| Drug | amiodarone | 7.24e-05 | 160 | 32 | 4 | CID000002156 | |
| Drug | triamterene | 7.38e-05 | 58 | 32 | 3 | CID000005546 | |
| Drug | Norepinephrine | 8.55e-05 | 10 | 32 | 2 | DB00368 | |
| Drug | Droxidopa | 8.55e-05 | 10 | 32 | 2 | DB06262 | |
| Drug | DO 710 | 8.55e-05 | 10 | 32 | 2 | CID003084985 | |
| Drug | Indans | 8.55e-05 | 10 | 32 | 2 | ctd:D007189 | |
| Drug | L-659,066 | 8.55e-05 | 10 | 32 | 2 | CID000163952 | |
| Drug | perflubron | 8.55e-05 | 10 | 32 | 2 | ctd:C003072 | |
| Drug | moclobemide | 9.01e-05 | 62 | 32 | 3 | CID000004235 | |
| Drug | bupranolol | 9.46e-05 | 63 | 32 | 3 | CID000002475 | |
| Drug | saxitoxin | 1.04e-04 | 65 | 32 | 3 | CID000037165 | |
| Drug | S-(-)-Lisuride | 1.04e-04 | 65 | 32 | 3 | CID000003938 | |
| Drug | CDK2 Inhibitor II | 1.04e-04 | 65 | 32 | 3 | CID005858639 | |
| Drug | repirinast | 1.04e-04 | 11 | 32 | 2 | CID000005050 | |
| Drug | 2,3,3',4,4',5-hexachlorobiphenyl | 1.04e-04 | 11 | 32 | 2 | ctd:C087667 | |
| Drug | RH-3421 | 1.04e-04 | 11 | 32 | 2 | CID000108039 | |
| Drug | chloroacetylajmaline | 1.04e-04 | 11 | 32 | 2 | CID000038681 | |
| Drug | SZL-49 | 1.25e-04 | 12 | 32 | 2 | CID000004892 | |
| Drug | CB149 | 1.25e-04 | 12 | 32 | 2 | CID000038016 | |
| Drug | Ro 22-9194 | 1.25e-04 | 12 | 32 | 2 | CID000129209 | |
| Drug | BDF 6143 | 1.25e-04 | 12 | 32 | 2 | CID000131283 | |
| Drug | T2755 | 1.35e-04 | 71 | 32 | 3 | CID000005514 | |
| Drug | synthetic pyrethrins | 1.35e-04 | 71 | 32 | 3 | CID000002982 | |
| Drug | carteolol | 1.41e-04 | 72 | 32 | 3 | CID000002583 | |
| Drug | indoramin | 1.48e-04 | 13 | 32 | 2 | CID000033625 | |
| Drug | 3,4,5,3',4',5'-hexachlorobiphenyl | 1.48e-04 | 13 | 32 | 2 | ctd:C027309 | |
| Drug | 1H,1H,2H,2H-perfluorodecanol | 1.48e-04 | 13 | 32 | 2 | ctd:C033729 | |
| Drug | CID6432355 | 1.48e-04 | 13 | 32 | 2 | CID006432355 | |
| Drug | dimethindene | 1.48e-04 | 13 | 32 | 2 | CID000021855 | |
| Drug | AC1LCJM3 | 1.48e-04 | 13 | 32 | 2 | CID000631640 | |
| Drug | GTP[S] | 1.52e-04 | 591 | 32 | 6 | CID000001764 | |
| Drug | Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A | 1.55e-04 | 195 | 32 | 4 | 5669_UP | |
| Drug | Gi-2 | 1.55e-04 | 195 | 32 | 4 | CID011957432 | |
| Drug | Diperodon hydrochloride [537-12-2]; Down 200; 9.2uM; HL60; HG-U133A | 1.59e-04 | 196 | 32 | 4 | 1575_DN | |
| Drug | Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A | 1.59e-04 | 196 | 32 | 4 | 6061_UP | |
| Drug | diphenhydramine | 1.59e-04 | 75 | 32 | 3 | CID000003100 | |
| Drug | Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A | 1.62e-04 | 197 | 32 | 4 | 2070_DN | |
| Drug | fludrocortisone | 1.65e-04 | 76 | 32 | 3 | CID000031378 | |
| Drug | 4,4'-bisphenol F | 1.65e-04 | 76 | 32 | 3 | ctd:C008745 | |
| Drug | Tiabendazole [148-79-8]; Up 200; 19.8uM; PC3; HT_HG-U133A | 1.71e-04 | 200 | 32 | 4 | 4579_UP | |
| Drug | deriglidole | 1.72e-04 | 14 | 32 | 2 | CID000065945 | |
| Drug | clobenpropit | 1.72e-04 | 14 | 32 | 2 | ctd:C086108 | |
| Drug | MK-912 | 1.72e-04 | 14 | 32 | 2 | CID000123679 | |
| Drug | 3-hydroxy-4-methoxycinnamic acid | 1.72e-04 | 14 | 32 | 2 | CID000092126 | |
| Drug | lorcainide | 1.72e-04 | 14 | 32 | 2 | CID000042883 | |
| Drug | octylguanidine | 1.72e-04 | 14 | 32 | 2 | CID000030621 | |
| Drug | SKF 104078 | 1.99e-04 | 15 | 32 | 2 | CID000122295 | |
| Drug | trimethyloxonium | 1.99e-04 | 15 | 32 | 2 | CID000093245 | |
| Drug | amosulalol | 1.99e-04 | 15 | 32 | 2 | CID000002169 | |
| Drug | HV723 | 1.99e-04 | 15 | 32 | 2 | CID003081094 | |
| Drug | AC1L1W4O | 1.99e-04 | 15 | 32 | 2 | CID000036625 | |
| Drug | dalcetrapib | 1.99e-04 | 15 | 32 | 2 | ctd:C411602 | |
| Drug | bupropion | 2.00e-04 | 81 | 32 | 3 | CID000000444 | |
| Drug | AC1NB8R3 | 2.18e-04 | 213 | 32 | 4 | CID004489307 | |
| Drug | adenosine 3',5'-cyclic phosphate | 2.19e-04 | 907 | 32 | 7 | CID000000274 | |
| Drug | Sodium | 2.22e-04 | 84 | 32 | 3 | ctd:D012964 | |
| Drug | 1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene | 2.27e-04 | 16 | 32 | 2 | ctd:C055238 | |
| Drug | fluparoxan | 2.27e-04 | 16 | 32 | 2 | CID000072036 | |
| Drug | 3',4'-dimethoxyflavone | 2.27e-04 | 16 | 32 | 2 | ctd:C509288 | |
| Drug | brimonidine | 2.38e-04 | 86 | 32 | 3 | CID000002435 | |
| Drug | trans-permethrin | 2.38e-04 | 86 | 32 | 3 | CID000040159 | |
| Drug | mianserin | 2.47e-04 | 87 | 32 | 3 | CID000004184 | |
| Drug | tetracaine | 2.55e-04 | 88 | 32 | 3 | CID000005411 | |
| Drug | articaine | 2.57e-04 | 17 | 32 | 2 | CID000032169 | |
| Drug | Fadrozole | 2.57e-04 | 17 | 32 | 2 | ctd:D017316 | |
| Drug | imiloxan | 2.57e-04 | 17 | 32 | 2 | CID000133621 | |
| Disease | adrenal cortical adenoma (is_marker_for) | 1.21e-06 | 2 | 33 | 2 | DOID:0050891 (is_marker_for) | |
| Disease | Glucocorticoid-remediable aldosteronism | 1.21e-06 | 2 | 33 | 2 | C1260386 | |
| Disease | congenital adrenal hyperplasia (implicated_via_orthology) | 3.64e-06 | 3 | 33 | 2 | DOID:0050811 (implicated_via_orthology) | |
| Disease | primary hyperaldosteronism (is_implicated_in) | 1.21e-05 | 5 | 33 | 2 | DOID:446 (is_implicated_in) | |
| Disease | Conn Syndrome | 1.81e-05 | 6 | 33 | 2 | C1384514 | |
| Disease | Hyperaldosteronism | 1.81e-05 | 6 | 33 | 2 | C0020428 | |
| Disease | protocadherin alpha-7 measurement | 2.54e-05 | 7 | 33 | 2 | EFO_0801973 | |
| Disease | Pruritus | 3.38e-05 | 8 | 33 | 2 | C0033774 | |
| Disease | protein FAM163B measurement | 4.35e-05 | 9 | 33 | 2 | EFO_0802936 | |
| Disease | generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology) | 5.43e-05 | 10 | 33 | 2 | DOID:0111294 (implicated_via_orthology) | |
| Disease | Dravet syndrome (implicated_via_orthology) | 5.43e-05 | 10 | 33 | 2 | DOID:0080422 (implicated_via_orthology) | |
| Disease | androstenedione measurement | 5.43e-05 | 10 | 33 | 2 | EFO_0007972 | |
| Disease | 3-hydroxyanthranilate 3,4-dioxygenase measurement | 6.63e-05 | 11 | 33 | 2 | EFO_0021862 | |
| Disease | cell growth regulator with EF hand domain protein 1 measurement | 6.63e-05 | 11 | 33 | 2 | EFO_0801461 | |
| Disease | generalized epilepsy with febrile seizures plus (implicated_via_orthology) | 7.95e-05 | 12 | 33 | 2 | DOID:0060170 (implicated_via_orthology) | |
| Disease | congestive heart failure (biomarker_via_orthology) | 2.34e-04 | 107 | 33 | 3 | DOID:6000 (biomarker_via_orthology) | |
| Disease | polycystic ovary syndrome (biomarker_via_orthology) | 2.51e-04 | 21 | 33 | 2 | DOID:11612 (biomarker_via_orthology) | |
| Disease | apolipoprotein L1 measurement | 3.58e-04 | 25 | 33 | 2 | EFO_0021854 | |
| Disease | brain infarction (biomarker_via_orthology) | 6.27e-04 | 33 | 33 | 2 | DOID:3454 (biomarker_via_orthology) | |
| Disease | metastasis measurement, disease progression measurement | 6.65e-04 | 34 | 33 | 2 | EFO_0007675, EFO_0008336 | |
| Disease | myocardial infarction (biomarker_via_orthology) | 7.58e-04 | 160 | 33 | 3 | DOID:5844 (biomarker_via_orthology) | |
| Disease | epilepsy (implicated_via_orthology) | 7.99e-04 | 163 | 33 | 3 | DOID:1826 (implicated_via_orthology) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| FGNFWCEFWTSIDVL | 101 | P07550 | |
| FWEEERPFWEEEKTF | 86 | Q6NSX1 | |
| FFVSFKDIGWNDWII | 326 | P08476 | |
| CFIIFEDSSKSWVLW | 76 | Q9Y483 | |
| LPEVAESTWWFKSFF | 46 | Q8WWR9 | |
| LEFIENSWWTKFCGA | 286 | Q9NUN5 | |
| YSEKCDVFSWGIILW | 206 | O43318 | |
| EAAVWWYDLVICLDF | 171 | Q8TDT2 | |
| KQWIFFWFGLADIRD | 496 | Q8N159 | |
| NVWFAEFWEENFGCK | 356 | O00222 | |
| KVWKEHFEAWDCIFQ | 251 | P15538 | |
| GTVCFWQWDLESLKF | 296 | Q9NSI6 | |
| FWVGSKKTCFEWASF | 496 | Q9NPG1 | |
| KVWKEHFEAWDCIFQ | 251 | P19099 | |
| TEGFSEGFFAKWWRC | 206 | Q6UWU4 | |
| FWDLAQLFWDIYVDC | 91 | A0A1B0GTK4 | |
| EEEFIDWWSKFFASI | 1471 | O75923 | |
| FFISWDDFWDLICNL | 266 | Q8WU17 | |
| TLFEWDFGKEICVFW | 76 | Q9H3N8 | |
| FPVFAWKGESEDDFW | 276 | Q96HN2 | |
| FCVDDFTFLRDPWNW | 181 | P35499 | |
| WPFGWFLCKFVFTIV | 91 | P21462 | |
| FCVGEFTFLRDPWNW | 176 | Q15858 | |
| NDPFFSWGWEIEDCK | 386 | Q99457 | |
| FDEKPTWDIFKQFLW | 1616 | P14410 | |
| ICFWDWEKGEKLDYF | 1046 | Q8N122 | |
| FWAFGRAFCDVWAAV | 161 | P25100 | |
| DFETWKWRFEDSFGV | 166 | Q96S66 | |
| NIVKWFWKAVEFFDE | 651 | Q9HAU4 | |
| WYFLEIVFCKRKWEE | 136 | Q9NRZ7 | |
| FILAWIETWFLDFKV | 161 | O95772 | |
| FEDVAVYFSWKEWGL | 16 | Q9Y2P7 | |
| IFWDFLGEKYWSDLV | 831 | Q8IWB9 |