Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	L-lactate dehydrogenase activity	LDHAL6A LDHC	1.65e-04	5	82	2	GO:0004459
GeneOntologyMolecularFunction	lactate dehydrogenase activity	LDHAL6A LDHC	2.47e-04	6	82	2	GO:0004457
GeneOntologyCellularComponent	cell cortex	CTTNBP2 DST TCHP SPTAN1 PDE4DIP RDX CTNNA2 MTSS2	8.69e-05	371	80	8	GO:0005938
Domain	Spectrin	DST TRIO SYNE1 SPTAN1	2.35e-06	23	78	4	PF00435
Domain	Spectrin_repeat	DST TRIO SYNE1 SPTAN1	6.17e-06	29	78	4	IPR002017
Domain	Spectrin/alpha-actinin	DST TRIO SYNE1 SPTAN1	9.26e-06	32	78	4	IPR018159
Domain	SPEC	DST TRIO SYNE1 SPTAN1	9.26e-06	32	78	4	SM00150
Domain	DH_1	TRIO PLEKHG3 ECT2L VAV2	1.39e-04	63	78	4	PS00741
Domain	L-lactate_DH	LDHAL6A LDHC	1.71e-04	5	78	2	IPR011304
Domain	L-lactate_DH_AS	LDHAL6A LDHC	1.71e-04	5	78	2	IPR018177
Domain	L_LDH	LDHAL6A LDHC	1.71e-04	5	78	2	PS00064
Domain	RhoGEF	TRIO PLEKHG3 ECT2L VAV2	1.87e-04	68	78	4	SM00325
Domain	RhoGEF	TRIO PLEKHG3 ECT2L VAV2	2.09e-04	70	78	4	PF00621
Domain	DH_2	TRIO PLEKHG3 ECT2L VAV2	2.09e-04	70	78	4	PS50010
Domain	DH-domain	TRIO PLEKHG3 ECT2L VAV2	2.21e-04	71	78	4	IPR000219
Domain	-	TRIO PLEKHG3 ECT2L VAV2	2.21e-04	71	78	4	1.20.900.10
Domain	SH3	MIA3 AHI1 DST TRIO SPTAN1 VAV2	2.87e-04	216	78	6	PS50002
Domain	SH3_domain	MIA3 AHI1 DST TRIO SPTAN1 VAV2	3.16e-04	220	78	6	IPR001452
Domain	DNA/RNA_helicase_DEAH_CS	TTF2 DHX38 DHX35	4.17e-04	35	78	3	IPR002464
Domain	L-lactate/malate_DH	LDHAL6A LDHC	4.74e-04	8	78	2	IPR001557
Domain	Ldh_1_N	LDHAL6A LDHC	4.74e-04	8	78	2	PF00056
Domain	Lactate/malate_DH_N	LDHAL6A LDHC	4.74e-04	8	78	2	IPR001236
Domain	-	WDR3 VPS11 AHI1 APAF1 CFAP43 PLXNB2 ARPC1B	4.80e-04	333	78	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WDR3 VPS11 AHI1 APAF1 CFAP43 PLXNB2 ARPC1B	4.98e-04	335	78	7	IPR015943
Domain	DEAH_ATP_HELICASE	TTF2 DHX38 DHX35	5.32e-04	38	78	3	PS00690
Domain	-	LDHAL6A LDHC	6.08e-04	9	78	2	3.90.110.10
Domain	Lactate/malate_DH_C	LDHAL6A LDHC	6.08e-04	9	78	2	IPR022383
Domain	Lactate_DH/Glyco_Ohase_4_C	LDHAL6A LDHC	6.08e-04	9	78	2	IPR015955
Domain	Ldh_1_C	LDHAL6A LDHC	6.08e-04	9	78	2	PF02866
Domain	SH3_1	AHI1 DST TRIO SPTAN1 VAV2	6.18e-04	164	78	5	PF00018
Domain	WD40_repeat_dom	WDR3 VPS11 AHI1 APAF1 CFAP43 ARPC1B	1.51e-03	297	78	6	IPR017986
Domain	MIF4-like	NCBP1 BZW1	1.75e-03	15	78	2	IPR016021
Domain	-	NCBP1 BZW1	1.75e-03	15	78	2	1.25.40.180
Domain	SH3	MIA3 AHI1 TRIO SPTAN1 VAV2	2.10e-03	216	78	5	SM00326
Domain	DUF1605	DHX38 DHX35	2.25e-03	17	78	2	IPR011709
Domain	OB_NTP_bind	DHX38 DHX35	2.25e-03	17	78	2	PF07717
Domain	HA2	DHX38 DHX35	2.52e-03	18	78	2	SM00847
Domain	HA2	DHX38 DHX35	2.52e-03	18	78	2	PF04408
Domain	Helicase-assoc_dom	DHX38 DHX35	2.52e-03	18	78	2	IPR007502
Domain	CH	DST SYNE1 VAV2	2.54e-03	65	78	3	SM00033
Domain	CH	DST SYNE1 VAV2	3.14e-03	70	78	3	PF00307
Domain	-	DST SYNE1 VAV2	3.27e-03	71	78	3	1.10.418.10
Domain	CH	DST SYNE1 VAV2	3.53e-03	73	78	3	PS50021
Domain	CH-domain	DST SYNE1 VAV2	3.81e-03	75	78	3	IPR001715
Domain	Actinin_actin-bd_CS	DST SYNE1	4.12e-03	23	78	2	IPR001589
Domain	ACTININ_2	DST SYNE1	4.12e-03	23	78	2	PS00020
Domain	ACTININ_1	DST SYNE1	4.12e-03	23	78	2	PS00019
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	CCDC69 IVNS1ABP CTTNBP2 DST TRIO SYNE1 PDE4DIP ANKRD26 RDX DTNBP1 VAV2	2.55e-08	497	82	11	23414517
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	IVNS1ABP WDR3 TRIO SND1 TRIM28 SYNE1 SPTAN1 RAB3GAP2 POLR2A DHX38 ZNF280C RDX NCBP1 RO60 BZW1 KDM1A TSFM	3.05e-08	1425	82	17	30948266
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TLK2 MIA3 CTTNBP2 DST TRIO TRIM28 SYNE1 SPTAN1 PDE4DIP RDX CTNNA2 KDM1A GOLGB1 MTSS2	5.43e-08	963	82	14	28671696
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	DST TRIO SYNE1 SPTAN1 PDE4DIP DTNBP1 KDM1A	7.32e-08	151	82	7	17043677
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	WDR3 ZC3H7A DST SND1 PLEKHG3 SYNE1 POLR2A DHX38 CEP83 ECT2L CTNNA2 ZC3H7B MBD4 FHIP1A KDM1A GOLGB1	3.65e-07	1497	82	16	31527615
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST TRIO SYNE1 SPTAN1 PDE4DIP KDM1A	4.20e-07	120	82	6	31413325
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	BLVRA TTF2 SND1 TRIM28 RAB3GAP2 POLR2A DHX38 APAF1 ZC3H7B ARPC1B KDM1A	8.23e-07	704	82	11	29955894
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	IVNS1ABP FSIP2 DST TRIO PLEKHG3 SPTAN1 RAB3GAP2 NADK ANKRD26 TRIM68 GOLGB1 MTSS2	8.31e-07	861	82	12	36931259
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	WDR3 MIA3 SND1 TRIM28 POLR2A DHX38 DHX35 KDM1A RPS6KC1	9.92e-07	440	82	9	34244565
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TTF2 MIA3 CTTNBP2 FAM193A DST TCHP SPTAN1 NADK ANKRD26	1.11e-06	446	82	9	24255178
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TTF2 FAM193A DST SND1 TRIM28 POLR2A DHX38 ZNF280C ANKRD26 RDX PCCA GOLGB1	1.94e-06	934	82	12	33916271
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	MIA3 DST SND1 TRIM28 SYNE1 SPTAN1 POLR2A NCBP1 BZW1 PCCA VAV2	3.07e-06	807	82	11	30575818
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	DST TRIO PDE4DIP KDM1A GOLGB1	6.78e-06	111	82	5	22558309
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FAM204A WDR3 ZC3H7A MIA3 FAM193A SND1 TCHP SYNE1 SPTAN1 RAB3GAP2 APAF1 ANKRD26 PLXNB2 GOLGB1	9.25e-06	1487	82	14	33957083
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	IVNS1ABP BLVRA WDR3 MIA3 DST TRIO SND1 SPTAN1 RDX CTNNA2 BZW1 PLXNB2 TSFM	1.04e-05	1297	82	13	33545068
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	BLVRA WDR3 SND1 TRIM28 DHX38 RDX NCBP1 RO60 BZW1 PCCA ARPC1B KDM1A TSFM	1.23e-05	1318	82	13	30463901
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	VPS11 DST SYNE1 GOLGB1	1.27e-05	60	82	4	20682791
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	DST SYNE1 ANKRD26	1.40e-05	20	82	3	21689717
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	TTF2 SAMD9 DST TRIO RAB3GAP2 POLR2A ZNF280C BZW1	1.61e-05	472	82	8	38943005
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	BLVRA WDR3 TTF2 ZC3H7A DST SND1 TRIM28 PLEKHG3 SPTAN1 POLR2A DHX38 ARPC1B KDM1A	1.62e-05	1353	82	13	29467282
Pubmed	Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II.	SND1 POLR2A	1.64e-05	3	82	2	12234934
Pubmed	A protein interaction landscape of breast cancer.	UBR2 DST TRIO SND1 POLR2A RO60 CTNNA2 MBD4 ARPC1B	1.89e-05	634	82	9	34591612
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	ZC3H7A SND1 TRIM28 SYNE1 POLR2A DHX38 NCBP1 BZW1 ZC3H7B TSFM	2.03e-05	807	82	10	22681889
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	MIA3 DST SND1 TRIM28 SPTAN1 ZNF280C GOLGB1	2.35e-05	360	82	7	33111431
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	DST RAB3GAP2 POLR2A DHX38 APAF1 RDX CTNNA2 KDM1A	2.36e-05	498	82	8	36634849
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	WDR3 DST NMNAT1 SND1 TRIM28 SPTAN1 RDX NCBP1 ARPC1B	2.58e-05	660	82	9	32780723
Pubmed	Generation and analysis of 280,000 human expressed sequence tags.	DST PIK3CD RAB3GAP2 DHX38 PDE4DIP FHIP1A GOLGB1	2.70e-05	368	82	7	8889549
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	WDR3 DST SND1 TRIM28 PLEKHG3 SYNE1 POLR2A NCBP1 PLXNB2 KDM1A GOLGB1	2.84e-05	1024	82	11	24711643
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	WDR3 TTF2 ZC3H7A MIA3 TRIO NADK ANKRD26 PCCA FHIP1A TSFM	3.25e-05	853	82	10	28718761
Pubmed	The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes.	VPS11 RDX	3.28e-05	4	82	2	21148287
Pubmed	Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.	WDR3 TTF2	3.28e-05	4	82	2	12765969
Pubmed	Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.	PDE4DIP DTNBP1 GOLGB1	3.55e-05	27	82	3	18685082
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	TTF2 DST SND1 TRIM28 RAB3GAP2 ANKRD26 RDX BZW1 GOLGB1	4.45e-05	708	82	9	39231216
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TTF2 SND1 TRIM28 SPTAN1 RAB3GAP2 POLR2A PCCA KDM1A	4.69e-05	549	82	8	38280479
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TLK2 BLVRA ZC3H7A FAM193A SND1 SPTAN1 ANKRD26 DHX35 ARPC1B	5.29e-05	724	82	9	36232890
Pubmed	KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs.	TRIM28 POLR2A	5.47e-05	5	82	2	32402252
Pubmed	Characterization and expression pattern of the novel MIA homolog TANGO.	MIA3 CTAGE1	5.47e-05	5	82	2	15183315
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DST TRIO SND1 TRIM28 PIK3CD POLR2A NADK SFI1 CFAP43 ZC3H7B PLXNB2	5.65e-05	1105	82	11	35748872
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FAM193A DST RAB3GAP2 MORC4 PCCA KDM1A GOLGB1	6.03e-05	418	82	7	34709266
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TTF2 SND1 SPTAN1 NCBP1 SFI1 BZW1 KDM1A GOLGB1	7.05e-05	582	82	8	20467437
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	WDR3 DST SND1 TRIM28 PLEKHG3 SYNE1 SPTAN1 RDX DHX35 ARPC1B	7.91e-05	949	82	10	36574265
Pubmed	ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.	TRIO ANKRD26	8.19e-05	6	82	2	22666460
Pubmed	Interaction of Ras with p110γ is required for thymic β-selection in the mouse.	PIK3CD VAV2	8.19e-05	6	82	2	21930962
Pubmed	Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.	PIK3CD VAV2	8.19e-05	6	82	2	18191593
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	IVNS1ABP SAMD9 SND1 TRIM28 SPTAN1 DHX38	1.05e-04	316	82	6	31665637
Pubmed	The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling.	PIK3CD VAV2	1.14e-04	7	82	2	23499492
Pubmed	Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation.	POLR2A KDM1A	1.14e-04	7	82	2	26836306
Pubmed	Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.	IVNS1ABP POLR2A NCBP1	1.17e-04	40	82	3	23825951
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CTTNBP2 DST TRIO SND1 TRIM28 SV2A SYNE1 SPTAN1 PDE4DIP RDX CTNNA2 ARPC1B	1.30e-04	1431	82	12	37142655
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	BLVRA WDR3 SND1 TRIM28 POLR2A DHX38 NCBP1 BZW1 MBD4 KDM1A	1.36e-04	1014	82	10	32416067
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ZC3H7A DST SND1 SYNE1 SPTAN1 CTAGE1 CEP83 ANKRD26 RDX NCBP1 GOLGB1 RPS6KC1	1.39e-04	1442	82	12	35575683
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	UBR2 MIA3 CTTNBP2 DST TRIO	1.50e-04	212	82	5	33853758
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	IVNS1ABP SND1 TRIM28 SPTAN1 RAB3GAP2 POLR2A DHX38 RDX NCBP1 RO60 BZW1 ARPC1B	1.51e-04	1455	82	12	22863883
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	WDR3 DST SND1 SPTAN1 POLR2A DHX38 NCBP1 KDM1A	1.56e-04	653	82	8	22586326
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	CCDC69 WDR3 CATSPERE CTTNBP2 TCHP DHX35 PLXNB2 FHIP1A ARPC1B TSFM MTSS2	1.58e-04	1242	82	11	30973865
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	SPTAN1 POLR2A RDX NCBP1 KDM1A	1.74e-04	219	82	5	31353912
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	WDR3 SAMD9 DST NMNAT1 SND1 TRIM28 PLEKHG3 SPTAN1 DHX38 NCBP1 ARPC1B	1.76e-04	1257	82	11	36526897
Pubmed	Gain of LINC00624 Enhances Liver Cancer Progression by Disrupting the Histone Deacetylase 6/Tripartite Motif Containing 28/Zinc Finger Protein 354C Corepressor Complex.	SND1 TRIM28	1.96e-04	9	82	2	32869873
Pubmed	Radixin regulates cell migration and cell-cell adhesion through Rac1.	RDX VAV2	1.96e-04	9	82	2	22467863
Pubmed	Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex.	POLR2A NCBP1	1.96e-04	9	82	2	22767893
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	BLVRA WDR3 TTF2 MIA3 DST SND1 SYNE1 RAB3GAP2 DHX35 PLXNB2 GOLGB1 TSFM	1.96e-04	1496	82	12	32877691
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	AHI1 TRIO POLR2A PITPNA DTNBP1 KDM1A	2.07e-04	358	82	6	32460013
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	TLK2 SND1 TRIM28 RAB3GAP2 POLR2A DHX38 PITPNA NADK RO60 BZW1 ARPC1B	2.11e-04	1284	82	11	17353931
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	WDR3 DST TRIO SYNE1 SPTAN1 PDE4DIP RDX NCBP1 DHX35 TRIM68 MBD4	2.13e-04	1285	82	11	35914814
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	WDR3 POLR2A NCBP1 KDM1A TSFM	2.51e-04	237	82	5	29564676
Pubmed	Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.	TRIM28 POLR2A RO60 PCCA	2.53e-04	129	82	4	28973437
Pubmed	The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.	SND1 TRIM28 SPTAN1 NCBP1 ARPC1B	2.61e-04	239	82	5	26641092
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	ZC3H7A VPS11 MIA3 TCHP CEP83	3.26e-04	251	82	5	29778605
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	CTTNBP2 TRIO SYNE1 SPTAN1 CTNNA2	3.26e-04	251	82	5	27507650
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	UBR2 TRIM28 SPTAN1 POLR2A NCBP1 KDM1A	3.27e-04	390	82	6	17643375
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MIA3 TRIO TRIM28 SV2A SPTAN1 RAB3GAP2 PDE4DIP CTNNA2 PCCA RPS6KC1	3.45e-04	1139	82	10	36417873
Pubmed	TRIM28 functions as a negative regulator of aggresome formation.	SND1 TRIM28	3.57e-04	12	82	2	33783327
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	TTF2 DST RDX NCBP1	3.64e-04	142	82	4	30809309
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	ZC3H7A DST SND1 SYNE1 ZC3H7B	3.70e-04	258	82	5	37794589
Pubmed	ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation.	TRIO POLR2A DHX35	3.73e-04	59	82	3	34108663
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	DST SND1 SPTAN1 RDX CTNNA2 BZW1 GOLGB1	3.82e-04	565	82	7	25468996
Pubmed	Mechanochemical control of epidermal stem cell divisions by B-plexins.	CTNNA2 PLXNB2	4.21e-04	13	82	2	33637728
Pubmed	Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.	MIA3 CTAGE1	4.21e-04	13	82	2	11839810
Pubmed	Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies.	CTTNBP2 DTNBP1	4.21e-04	13	82	2	33374598
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	SV2A DTNBP1	4.21e-04	13	82	2	27713690
Pubmed	Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.	DST POLR2A NCBP1 RO60 KDM1A	4.63e-04	271	82	5	25737280
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ZC3H7A TCHP DHX38 ANKRD26 MORC4 KDM1A GOLGB1	4.85e-04	588	82	7	38580884
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DST TRIO ANKRD26 PLXNB2 GOLGB1 MTSS2	4.90e-04	421	82	6	36976175
Pubmed	Enzymology of NAD+ homeostasis in man.	NMNAT1 NADK	4.91e-04	14	82	2	14704851
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	TLK2 WDR3 SND1 TRIM28 POLR2A DHX38 ZNF280C PCCA KDM1A	5.37e-04	989	82	9	36424410
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	BLVRA WDR3 DST SND1 TRIM28 PLEKHG3 SPTAN1 NCBP1 CTNNA2 BZW1 ARPC1B	5.57e-04	1440	82	11	30833792
Pubmed	TRIM28 functions as the SUMO E3 ligase for PCNA in prevention of transcription induced DNA breaks.	TRIM28 POLR2A	5.65e-04	15	82	2	32900933
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	RSPH3 DST TRIO TRIM28 SPTAN1	5.73e-04	284	82	5	29459677
Pubmed	The DNA sequence of human chromosome 7.	BLVRA CTTNBP2 SAMD9 PON3 ARPC1B LRRC17	6.24e-04	441	82	6	12853948
Pubmed	Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase.	POLR2A NCBP1	6.45e-04	16	82	2	9409616
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	TLK2 SND1 TRIM28 RDX NCBP1 RO60	7.02e-04	451	82	6	36168627
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	ZC3H7A VPS11 PDE4DIP RDX GOLGB1	7.11e-04	298	82	5	32353859
Pubmed	Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae.	PIK3CD VAV2	7.30e-04	17	82	2	21257963
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	WDR3 SND1 TRIM28 SPTAN1 POLR2A NCBP1 KDM1A	7.83e-04	638	82	7	33239621
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	UBR2 MIA3 TRIO SPTAN1 POLR2A DHX38 ZNF280C NCBP1 DTNBP1	8.15e-04	1049	82	9	27880917
Pubmed	Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.	AHI1 CTNNA2	8.20e-04	18	82	2	33323119
Pubmed	FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region.	TLK2 RAB3GAP2	8.20e-04	18	82	2	16484223
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	DST TCHP SPTAN1 POLR2A ANKRD26 NCBP1 KDM1A	8.35e-04	645	82	7	25281560
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	LDHAL6A TRIM28 SPTAN1 RAB3GAP2 RDX NCBP1 ARPC1B	8.50e-04	647	82	7	26618866
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	VPS11 POLR2A NCBP1 KLHL12 PLXNB2	8.86e-04	313	82	5	38270169
Interaction	TNIK interactions	TLK2 CTTNBP2 DST TRIO TRIM28 SYNE1 SPTAN1 PDE4DIP CTNNA2 KDM1A MTSS2	3.54e-07	381	81	11	int:TNIK
Interaction	KDM1A interactions	FAM204A VPS11 FAM193A DST TRIM28 PLEKHG3 RAB3GAP2 POLR2A ZNF280C PDE4DIP MORC4 MBD4 PCCA KDM1A GOLGB1	4.43e-06	941	81	15	int:KDM1A
Interaction	ACTB interactions	IVNS1ABP FSIP2 TTF2 AHI1 CTTNBP2 DST TCHP TRIM28 PLEKHG3 SPTAN1 POLR2A RDX NCBP1 RO60 ARPC1B MTSS2	5.35e-06	1083	81	16	int:ACTB
Interaction	NIN interactions	WDR3 TTF2 MIA3 TRIO TCHP ANKRD26 DHX35 KDM1A TSFM	1.38e-05	359	81	9	int:NIN
Interaction	CTIF interactions	FAM193A SND1 TRIM28 NCBP1 FHIP1A	1.46e-05	77	81	5	int:CTIF
Interaction	IFI16 interactions	IVNS1ABP WDR3 SAMD9 NMNAT1 SND1 TRIM28 SYNE1 SPTAN1 POLR2A DHX38 NCBP1 ARPC1B	2.68e-05	714	81	12	int:IFI16
Interaction	PHF13 interactions	BLVRA TRIM28 KDM1A	2.75e-05	15	81	3	int:PHF13
Interaction	DCTN1 interactions	TTF2 ZC3H7A AHI1 DST TRIM28 RAB3GAP2 BZW1 DTNBP1 KDM1A TSFM	2.98e-05	497	81	10	int:DCTN1
Interaction	CDC5L interactions	TTF2 DST NMNAT1 TRIO SYNE1 SPTAN1 POLR2A DHX38 PDE4DIP SFI1 BZW1 KDM1A GOLGB1	3.42e-05	855	81	13	int:CDC5L
Interaction	PCNT interactions	DST TCHP SYNE1 SPTAN1 RDX DTNBP1 KDM1A	5.25e-05	241	81	7	int:PCNT
Interaction	KLC1 interactions	TRIM28 NCBP1 RO60 BZW1 DTNBP1 FHIP1A KDM1A	7.49e-05	255	81	7	int:KLC1
Interaction	ZSCAN26 interactions	TRIO SPTAN1 PDE4DIP NCBP1	9.32e-05	59	81	4	int:ZSCAN26
Interaction	ZNF333 interactions	TRIM28 SPTAN1 KDM1A	1.19e-04	24	81	3	int:ZNF333
Interaction	SMARCC1 interactions	SAMD9 TRIM28 SPTAN1 RAB3GAP2 POLR2A RO60 BZW1 KDM1A	1.55e-04	384	81	8	int:SMARCC1
Interaction	MKRN2 interactions	ZC3H7A AHI1 TRIO PITPNA APAF1 ANKRD26 DTNBP1 KDM1A	1.57e-04	385	81	8	int:MKRN2
Interaction	CTAGE15 interactions	MIA3 CTAGE1	1.58e-04	5	81	2	int:CTAGE15
Interaction	RCOR1 interactions	FAM193A DST TRIM28 SPTAN1 RAB3GAP2 BZW1 MORC4 PCCA KDM1A	1.62e-04	494	81	9	int:RCOR1
Interaction	ARRDC1 interactions	POLR2A KLHL12 ZC3H7B KDM1A	1.62e-04	68	81	4	int:ARRDC1
Cytoband	1q41	MIA3 RAB3GAP2 RPS6KC1	2.32e-04	66	82	3	1q41
Cytoband	9q34.1	NCBP1 VAV2	5.28e-04	19	82	2	9q34.1
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TRIO PLEKHG3 ECT2L VAV2	3.03e-05	66	49	4	722
GeneFamily	WD repeat domain containing	WDR3 AHI1 APAF1 CFAP43 ARPC1B	6.97e-04	262	49	5	362
GeneFamily	DEAH-box helicases	DHX38 DHX35	8.43e-04	16	49	2	500
Coexpression	GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP	RSPH3 RAB3GAP2 PON3 KLHL12 ZC3H7B FHIP1A VAV2	3.07e-06	199	82	7	M2934
Coexpression	GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP	IVNS1ABP MIA3 SV2A POLR2A CEP83 GOLGB1 IQCK	3.18e-06	200	82	7	M9889
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	DST SYNE1 SPTAN1 ANKRD26 GOLGB1 MTSS2	9.31e-07	177	82	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	ASK454-Epithelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	DST SPTAN1 RDX CFAP43 IQCK	2.17e-05	182	82	5	ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TTF2 DHRS12 ANKRD26 NCBP1 KLHL12	2.48e-05	187	82	5	c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA3 CTTNBP2 DST SV2A GOLGB1	2.54e-05	188	82	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	TMEM232 SYNE1 ECT2L CFAP43 IQCK	2.88e-05	193	82	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA3 AHI1 CTTNBP2 DST TRIO	3.02e-05	195	82	5	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	Mild\|World / Condition, Lineage, Cell class and cell subclass	MIA3 SAMD9 DST RBM43 GOLGB1	3.18e-05	197	82	5	476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RSPH3 TMEM232 SYNE1 ECT2L CFAP43	3.25e-05	198	82	5	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TLK2 UBR2 SYNE1 SFI1 GOLGB1	3.33e-05	199	82	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CTTNBP2 SYNE1 SPTAN1 PDE4DIP CTNNA2	3.41e-05	200	82	5	44bc4d6616fc8d0ad8498e56125939034e8cff01
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CTTNBP2 SV2A SPTAN1 PDE4DIP CTNNA2	3.41e-05	200	82	5	09fd3cb31bcc02444f1045f01fe39bce09359d35
Computational	Genes upregulated in subsets of cells of a given type within various tumors	DST TRIO SYNE1 GOLGB1	9.51e-05	50	52	4	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; HL60; HT_HG-U133A	WDR3 UBR2 TTF2 PIK3CD POLR2A NADK KDM1A TSFM	3.48e-07	185	82	8	1833_DN
Drug	Isometheptene mucate; Down 200; 8.2uM; MCF7; HT_HG-U133A	CCDC69 DHRS12 AHI1 PDE4DIP ANKRD26 RO60 SFI1 MBD4	5.84e-07	198	82	8	6524_DN
Drug	Homatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	BLVRA SND1 PDE4DIP ANKRD26 DHX35 RO60 ZC3H7B	6.93e-06	196	82	7	1684_DN
Drug	Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; PC3; HT_HG-U133A	TRIO PDE4DIP ANKRD26 NCBP1 SFI1 ZC3H7B VAV2	7.17e-06	197	82	7	3708_DN
Drug	Colistin sulfate [1264-72-8]; Down 200; 3uM; MCF7; HT_HG-U133A	CCDC69 FAM204A PIK3CD SPTAN1 PDE4DIP NADK RO60	7.17e-06	197	82	7	4796_DN
Drug	Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; HL60; HT_HG-U133A	AHI1 APAF1 NADK NCBP1 RO60 SFI1 VAV2	7.41e-06	198	82	7	1272_UP
Drug	Merbromin [129-16-8]; Down 200; 5uM; PC3; HT_HG-U133A	TRIO SYNE1 PDE4DIP CEP83 NADK DHX35 ZC3H7B	7.66e-06	199	82	7	7398_DN
Drug	Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	SAMD9 PLEKHG3 SPTAN1 RO60 SFI1 ZC3H7B VAV2	7.66e-06	199	82	7	4806_DN
Drug	Strophanthidin [66-28-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A	DHRS12 AHI1 PLEKHG3 APAF1 DHX35 SFI1 TSFM	7.91e-06	200	82	7	7182_DN
Drug	0297417-0002B [362658-29-5]; Up 200; 10uM; MCF7; HT_HG-U133A	DHRS12 PDE4DIP NADK SFI1 ZC3H7B LRRC17	5.74e-05	186	82	6	6900_UP
Drug	Acacetin [480-44-4]; Down 200; 14uM; HL60; HT_HG-U133A	CCDC69 BLVRA PDE4DIP ANKRD26 SFI1 TSFM	6.46e-05	190	82	6	2189_DN
Drug	2-ethylhexanol	LDHAL6A RDX LDHC	6.60e-05	22	82	3	CID000007720
Drug	C75; Down 200; 10uM; MCF7; HT_HG-U133A	BLVRA AHI1 TRIO PDE4DIP APAF1 SFI1	6.84e-05	192	82	6	6423_DN
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A	AHI1 SYNE1 NADK SFI1 IQCK MTSS2	7.04e-05	193	82	6	2675_DN
Drug	Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	AHI1 SAMD9 SND1 DHX35 ZC3H7B GOLGB1	7.24e-05	194	82	6	4804_DN
Drug	Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; MCF7; HT_HG-U133A	CCDC69 AHI1 SPTAN1 NCBP1 RO60 SFI1	7.24e-05	194	82	6	4387_DN
Drug	Hemicholinium bromide [312-45-8]; Down 200; 7uM; PC3; HT_HG-U133A	TRIO SPTAN1 RAB3GAP2 SFI1 ZC3H7B MTSS2	7.45e-05	195	82	6	6739_DN
Drug	5-aza-2′-deoxycytidine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	TRIO APAF1 DHX35 RO60 VAV2 MTSS2	7.45e-05	195	82	6	920_UP
Drug	Erythromycin [114-07-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A	CCDC69 AHI1 TRIO PDE4DIP NCBP1 VAV2	7.45e-05	195	82	6	5329_UP
Drug	Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A	AHI1 SPTAN1 POLR2A PDE4DIP NADK SFI1	7.45e-05	195	82	6	6245_UP
Drug	m-phenylenediamine	SYNE1 RDX LDHC	7.57e-05	23	82	3	CID000007935
Drug	ox-Q	LDHAL6A LDHC	7.65e-05	4	82	2	CID000448650
Drug	Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A	DHRS12 PLEKHG3 RAB3GAP2 PDE4DIP DHX35 LRRC17	7.67e-05	196	82	6	4324_UP
Drug	Iodipamide [606-17-7]; Up 200; 3.6uM; MCF7; HT_HG-U133A	AHI1 SND1 SV2A PIK3CD APAF1 LRRC17	7.67e-05	196	82	6	5510_UP
Drug	Hydrocortisone base [50-23-7]; Down 200; 11uM; PC3; HT_HG-U133A	TTF2 SPTAN1 RAB3GAP2 PDE4DIP NCBP1 SFI1	7.67e-05	196	82	6	6684_DN
Drug	ICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A	CCDC69 BLVRA SAMD9 ZC3H7B PCCA GOLGB1	7.67e-05	196	82	6	1146_DN
Drug	Midecamycin [35457-80-8]; Down 200; 5uM; PC3; HT_HG-U133A	TRIO PLEKHG3 SPTAN1 RAB3GAP2 ANKRD26 MTSS2	7.67e-05	196	82	6	6745_DN
Drug	Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A	SAMD9 SPTAN1 PDE4DIP APAF1 NADK SFI1	7.67e-05	196	82	6	6229_UP
Drug	Deferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A	DHRS12 PDE4DIP APAF1 ANKRD26 ZC3H7B VAV2	7.67e-05	196	82	6	4317_UP
Drug	PNU-0251126 [267429-19-6]; Down 200; 1uM; MCF7; HT_HG-U133A	AHI1 SAMD9 TRIO SPTAN1 PDE4DIP RO60	7.89e-05	197	82	6	4714_DN
Drug	Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; HL60; HT_HG-U133A	SPTAN1 PDE4DIP NADK SFI1 ZC3H7B IQCK	7.89e-05	197	82	6	2985_DN
Drug	Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; MCF7; HT_HG-U133A	SAMD9 NADK ANKRD26 RO60 SFI1 MTSS2	7.89e-05	197	82	6	3215_DN
Drug	Droperidol [548-73-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	SND1 SPTAN1 PDE4DIP ANKRD26 SFI1 TSFM	8.11e-05	198	82	6	5690_DN
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; PC3; HT_HG-U133A	BLVRA SAMD9 SPTAN1 APAF1 PCCA TSFM	8.11e-05	198	82	6	2115_DN
Drug	Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A	CCDC69 PLEKHG3 PDE4DIP ANKRD26 ZC3H7B VAV2	8.11e-05	198	82	6	1491_DN
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A	TTF2 DHRS12 TRIO PLEKHG3 PDE4DIP STRA6	8.11e-05	198	82	6	6030_DN
Drug	Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; PC3; HT_HG-U133A	AHI1 SAMD9 TRIO PIK3CD SPTAN1 DHX38	8.11e-05	198	82	6	5829_DN
Drug	Lactobionic acid [96-82-2]; Down 200; 11.2uM; HL60; HT_HG-U133A	BLVRA PLEKHG3 RDX NCBP1 RO60 TSFM	8.11e-05	198	82	6	1309_DN
Drug	Flufenamic acid [530-78-9]; Down 200; 14.2uM; PC3; HT_HG-U133A	AHI1 TRIO SYNE1 SPTAN1 SFI1 ZC3H7B	8.11e-05	198	82	6	5059_DN
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A	DHRS12 APAF1 NADK RO60 SFI1 STRA6	8.34e-05	199	82	6	4984_UP
Drug	Carbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A	FAM204A SND1 PDE4DIP APAF1 ZC3H7B VAV2	8.34e-05	199	82	6	5093_UP
Drug	0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A	SND1 APAF1 PON3 NCBP1 VAV2 MTSS2	8.34e-05	199	82	6	3774_UP
Drug	Bromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A	FAM204A SPTAN1 ANKRD26 NCBP1 ZC3H7B TSFM	8.34e-05	199	82	6	4278_DN
Drug	Lobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; PC3; HT_HG-U133A	FAM204A SAMD9 SYNE1 SFI1 ZC3H7B TSFM	8.34e-05	199	82	6	5784_DN
Drug	Cortisone [53-06-5]; Down 200; 11uM; HL60; HT_HG-U133A	AHI1 SND1 PIK3CD PITPNA SFI1 PCCA	8.57e-05	200	82	6	2385_DN
Drug	Palmatine chloride [3486-67-7]; Down 200; 10.4uM; PC3; HT_HG-U133A	AHI1 SAMD9 TRIO SND1 SYNE1 IQCK	8.57e-05	200	82	6	6612_DN
Drug	spirobishexahydropyrimidine	LDHAL6A LDHC	1.27e-04	5	82	2	CID000100750
Drug	AC1O5TJF	LDHAL6A LDHC	1.27e-04	5	82	2	CID006440410
Drug	1,4-diethoxybutane	LDHAL6A LDHC	1.27e-04	5	82	2	CID000232578
Drug	C4H3NO4	LDHAL6A LDHC	1.27e-04	5	82	2	CID000448651
Drug	S-lac-NAD	LDHAL6A LDHC	1.27e-04	5	82	2	CID000194292
Drug	sorbarin	LDHAL6A LDHC	1.27e-04	5	82	2	CID009824100
Drug	AC1O5ZB9	LDHAL6A LDHC	1.27e-04	5	82	2	CID006443605
Drug	AC1L49DG	LDHAL6A LDHC	1.27e-04	5	82	2	CID000152931
Drug	N-trifluoroacetyl-glycine	LDHAL6A LDHC	1.27e-04	5	82	2	CID000136227
Drug	acetylphosphonic acid	LDHAL6A LDHC	1.27e-04	5	82	2	CID000081311
Drug	NSC-60195	LDHAL6A LDHC	1.27e-04	5	82	2	CID000020481
Drug	ethyl gossypol	LDHAL6A LDHC	1.27e-04	5	82	2	CID000374353
Drug	oxyayanin A	LDHAL6A LDHC	1.27e-04	5	82	2	CID005281676
Drug	B-HAD	LDHAL6A LDHC	1.27e-04	5	82	2	CID000131338
Drug	SQ 31,486	LDHAL6A LDHC	1.27e-04	5	82	2	CID000130015
Drug	BMS-188107	LDHAL6A LDHC	1.27e-04	5	82	2	CID000192297
Drug	BL-443	LDHAL6A LDHC	1.90e-04	6	82	2	CID000054436
Drug	dansyl-L-lysine	LDHAL6A LDHC	1.90e-04	6	82	2	CID000598797
Drug	I 65	LDHAL6A LDHC	1.90e-04	6	82	2	CID000149068
Drug	D 701	LDHAL6A LDHC	1.90e-04	6	82	2	CID003051460
Drug	2,3-dihydroxy-1-naphthoic acid	LDHAL6A LDHC	1.90e-04	6	82	2	CID000028002
Drug	AC1L24G8	LDHAL6A LDHC	1.90e-04	6	82	2	CID000066023
Drug	oxymethacil	LDHAL6A LDHC	1.90e-04	6	82	2	CID000096369
Drug	SQ 32,926	LDHAL6A LDHC	1.90e-04	6	82	2	CID000131363
Drug	AC1Q6L57	LDHAL6A CRTAM LDHC	2.49e-04	34	82	3	CID000090740
Drug	AC1O7170	LDHAL6A LDHC	2.66e-04	7	82	2	CID006540699
Drug	BS35	LDHAL6A LDHC	2.66e-04	7	82	2	CID000029316
Drug	BS36	LDHAL6A LDHC	2.66e-04	7	82	2	CID000029308
Drug	pentabromoacetone	LDHAL6A LDHC	2.66e-04	7	82	2	CID000065579
Drug	methyl-4-hydroxy-3-nitrobenzimidate	LDHAL6A LDHC	2.66e-04	7	82	2	CID005492576
Drug	gossylic iminolactone	LDHAL6A LDHC	2.66e-04	7	82	2	CID005479302
Drug	N-acetyl-9-O-lactylneuraminic acid	LDHAL6A LDHC	2.66e-04	7	82	2	CID000191486
Drug	sodium glycolate	LDHAL6A LDHC	2.66e-04	7	82	2	CID000517347
Drug	AC1NSM0G	LDHAL6A LDHC	2.66e-04	7	82	2	CID005365671
Drug	NHE-1 inhibitor	LDHAL6A RDX LDHC	3.20e-04	37	82	3	CID011515636
Drug	p-(phenoxypropoxy)aniline	LDHAL6A LDHC	3.54e-04	8	82	2	CID000423258
Drug	BS37	LDHAL6A LDHC	3.54e-04	8	82	2	CID000027925
Drug	U75412E	LDHAL6A LDHC	3.54e-04	8	82	2	CID003035460
Drug	AC1Q3O0A	LDHAL6A LDHC	3.54e-04	8	82	2	CID000060880
Drug	UR-12633	LDHAL6A LDHC	3.54e-04	8	82	2	CID000128030
Drug	2-methyl-2-pentenoate	LDHAL6A LDHC	3.54e-04	8	82	2	CID000018458
Drug	AC1L4GHU	LDHAL6A LDHC	3.54e-04	8	82	2	CID000156607
Drug	N-dodecyl morpholine	LDHAL6A LDHC	3.54e-04	8	82	2	CID000073764
Drug	S-(2-chloroethyl)-L-cysteine	LDHAL6A LDHC	3.54e-04	8	82	2	CID000034229
Drug	benzamyl	LDHAL6A LDHC	4.54e-04	9	82	2	CID000160884
Drug	Bcdfg	LDHAL6A LDHC	4.54e-04	9	82	2	CID003036106
Drug	N-acetyl-ala-ala-ala-methyl ester	LDHAL6A LDHC	4.54e-04	9	82	2	CID000100120
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	BLVRA MIA3 PIK3CD SPTAN1 PDE4DIP	5.12e-04	182	82	5	5511_UP
Drug	2,3-butanedione	LDHAL6A RDX LDHC TSFM	5.27e-04	103	82	4	CID000000650
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	PDE4DIP ANKRD26 RO60 SFI1 ZC3H7B	5.66e-04	186	82	5	6987_UP
Drug	trichostatin A; Up 200; 0.1uM; MCF7; HG-U133A	BLVRA PIK3CD PITPNA PDE4DIP NADK	5.66e-04	186	82	5	332_UP
Drug	hydroxyisonobilin	LDHAL6A LDHC	5.66e-04	10	82	2	CID006438562
Drug	pyridinophane cryptand	LDHAL6A LDHC	5.66e-04	10	82	2	CID006454246
Drug	sodium oxamate	LDHAL6A LDHC	5.66e-04	10	82	2	CID000005242
Disease	interleukin 10 measurement	MIA3 MACROD2 CTNNA2 DTNBP1	6.76e-05	78	82	4	EFO_0004750
Disease	corpus callosum anterior volume measurement	CTTNBP2 SND1 PCCA	1.76e-04	39	82	3	EFO_0010295
Disease	urate measurement, bone density	FSIP2 EYS SYNE1 CEP83 DHX35 CTNNA2 DTNBP1 KCNH5	3.27e-04	619	82	8	EFO_0003923, EFO_0004531
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TLK2 TRIO	1.01e-03	17	82	2	DOID:0060307 (is_implicated_in)
Disease	selenium measurement, response to dietary selenium supplementation	ZC3H7A TRIO	1.40e-03	20	82	2	EFO_0006331, EFO_0600021
Disease	Retinal Degeneration	AHI1 NMNAT1	1.55e-03	21	82	2	C0035304
Disease	disease of metabolism (implicated_via_orthology)	LDHAL6A LDHC	1.55e-03	21	82	2	DOID:0014667 (implicated_via_orthology)
Disease	Intellectual Disability	TLK2 AHI1 TRIO SYNE1 CTNNA2 STRA6	1.55e-03	447	82	6	C3714756
Disease	post-traumatic stress disorder symptom measurement	CTTNBP2 SYNE1 MACROD2	1.56e-03	82	82	3	EFO_0008535

Protein segments in the cluster

Peptide	Gene	Start	Entry
KTVNDKIWQEHSKHK	nan	81	A8MT66
KIWQEHSKHKNDSHI	nan	86	A8MT66
QHKKTVWHIQFTADE	APAF1	1001	O14727
PWHKAKELIVNHEKE	CFAP43	1091	Q8NDM7
KELIVNHEKEHWLLI	CFAP43	1096	Q8NDM7
HEAQTWKSMIELNKH	CATSPERE	806	Q5SY80
KIILHEKKAHDNWSA	CTAGE1	421	Q96RT6
WNKKEELVAEQAIKH	BZW1	306	Q7L1Q6
EHSVHHWTINKEIKE	AHI1	781	Q8N157
KWTKVHELKEHNGQV	ARPC1B	41	O15143
LLSKKNWHGVHKNDD	ECT2L	266	Q008S8
KQIQWLEEKHKLHER	CEP83	531	Q9Y592
KEIKSQLEHQKVEWE	ANKRD26	771	Q9UPS8
ENEHLKKFQVTWELH	FAM193A	56	P78312
MWNKFQELHKKHSEQ	FAM204A	76	Q9H8W3
QHEEEKKKWAQQVEK	CCDC69	66	A6NI79
NNAKHVKELIEEWSH	RBM43	271	Q6ZSC3
TQENVHKLEPEAWKH	PITPNA	121	Q00169
KHIHQQVKIFWAKQE	IQCK	251	Q8N0W5
KKKEEEATEWQHKAF	RDX	436	P35241
GWKSKHEEEAVQKQK	RAB3GAP2	351	Q9H2M9
QEGWLKVDDHKNKSI	EYS	2521	Q5T1H1
ENLHCIIKSHWKERK	NCBP1	316	Q09161
KHEWKIVASEKTSNN	IVNS1ABP	286	Q9Y6Y0
DFKKLHKELWQIHKN	RPS6KC1	56	Q96S38
EHVEKAKELQKWVSN	DST	1441	Q03001
WEKKHRDHTAKKQSV	LRRC17	421	Q8N6Y2
HEEKKEDWNNVTKAE	KCNH5	821	Q8NCM2
KDEKVKSQEQIPNHW	FSIP2	1021	Q5CZC0
KQAEIWLHKEAQKEG	TSFM	76	P43897
HWNVRKKQAHFEEEE	NADK	426	O95544
EKHNIQDEDTIHIWK	PLXNB2	1666	O15031
IEDWKKAANQLDKDH	MTSS2	111	Q765P7
HWEKKKTSLVELQEQ	DTNBP1	86	Q96EV8
DSDKEHWKNIHKQVI	LDHC	221	P07864
IANWELSVKLHDKVH	PCCA	556	P05165
NHWAQVVKILEKHDP	FHIP1A	31	Q05DH4
VFEAVINWVKHAKKE	KLHL12	196	Q53G59
KHVKDEQIEHWKKIV	KDM1A	421	O60341
HQEKSKLDAEVAKWD	CTNNA2	691	P26232
HVIWKKENEVSEHTL	CRTAM	316	O95727
KEVNWNLHKNEHLEK	CTTNBP2	1646	Q8WZ74
IKHNKDSKWCQEHFL	DHX35	556	Q9H5Z1
IWKFVENFKQEHKLH	DHRS12	106	A0PJE2
WELAEQKGKVLHEEH	BLVRA	111	P53004
NEWKQVHPEDHKLNK	MBD4	551	O95243
KEWLAKNHHEVDRII	MACROD2	206	A1Z1Q3
KQKVVSAVKHHQHWQ	SFI1	271	A8K8P3
HEHELCWLKDKAKQI	SYNE1	2031	Q8NF91
KEDWKNFHSNLHQKE	SYNE1	3151	Q8NF91
IQLHQMKKWHEEVTA	SYNE1	3636	Q8NF91
IATHEKKAHENWLKA	MIA3	1591	Q5JRA6
AKTVEEKRNWTHHIK	PLEKHG3	376	A1L390
QWLESHKIDQKHREI	SAMD9	21	Q5K651
HNWKIAHVVLKEEQK	MEP1A	386	Q16819
NHWQSEFKKVQHELV	MORC4	801	Q8TE76
AEEAAKQKKEKVWAH	SND1	646	Q7KZF4
KKQEEAWEQAQHRDH	IL9R	186	Q01113
EHLLTNHLKSKEVWK	RO60	256	P10155
EDKQEVVELVKHHLW	STRA6	346	Q9BX79
KHDEAWMVLKQVHDT	SV2A	366	Q7L0J3
NKNWRDEKKENYHKH	TLK2	496	Q86UE8
QWEIMHKHNETSQKI	RSPH3	381	Q86UC2
EKWKLDKHQKTHAEE	ZIM3	206	Q96PE6
HEALEHLKKEQEEAW	TRIM68	146	Q6AZZ1
LQNWAHEKDPQVKEK	VPS11	631	Q9H270
TKADKELAKIIDHHW	TMEM232	586	C9JQI7
ELAKIIDHHWQEELK	TMEM232	591	C9JQI7
IDHHWQEELKIREKE	TMEM232	596	C9JQI7
HELNQKWEALKAKAS	SPTAN1	866	Q13813
EWKHVNEDSQEKKIL	POLR2A	201	P24928
KNWEEHSVKDKHNTK	ZNF556	86	Q9HAH1
HEKDLVWKLRHEVQE	PIK3CD	526	O00329
EQKERKKAQHKHWEL	DHX38	456	Q92620
AKNIHIMEKHDNWDL	PON3	241	Q15166
DLHQKHVVNSWEMQK	TCHP	156	Q9BT92
QWQGHISSEKHKEKV	ZC3H7A	871	Q8IWR0
KHHLELEKQNNESWE	ZNF280C	336	Q8ND82
EVKHIKVVEKDNWIH	VAV2	716	P52735
KVVEKDNWIHITEAK	VAV2	721	P52735
KIKQWDADKFEHIQT	WDR3	656	Q9UNX4
FKKIQKLWHQHSVTE	UBR2	1721	Q8IWV8
LKASSIENKQDWIKH	TRIO	1571	O75962
QHWTMTKIQKHQEHI	TRIM28	331	Q13263
SLIHHWKNEVEKRVN	TTF2	651	Q9UNY4
QWQQHIQSEKHKEKV	ZC3H7B	856	Q9UGR2
SKIAESTEWQEKHKE	GOLGB1	1596	Q14789
DKDPEQWENVHKKVI	LDHAL6A	221	Q6ZMR3
ELQDKKQHLDKTWAD	PDE4DIP	61	Q5VU43
EWKETLKVLRHHQEK	NMNAT1	91	Q9HAN9