Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	kainate selective glutamate receptor activity	GRIK1 GRIK2 GRIK3	6.93e-06	6	142	3	GO:0015277
GeneOntologyMolecularFunction	glutamate-gated receptor activity	GRIK1 GRIK2 GRIK3	2.23e-04	17	142	3	GO:0004970
GeneOntologyMolecularFunction	ligand-gated sodium channel activity	GRIK1 GRIK2 GRIK3	2.66e-04	18	142	3	GO:0015280
GeneOntologyCellularComponent	kainate selective glutamate receptor complex	GRIK1 GRIK2 GRIK3	6.05e-06	6	142	3	GO:0032983
Domain	Neurogenic_DUF	NEUROD4 NEUROD1 NEUROD2 NEUROD6	2.85e-09	4	138	4	IPR022575
Domain	Neuro_bHLH	NEUROD4 NEUROD1 NEUROD2 NEUROD6	2.85e-09	4	138	4	PF12533
Domain	TF_bHLH_NeuroD	NEUROD4 NEUROD1 NEUROD2 NEUROD6	2.85e-09	4	138	4	IPR016637
Domain	HLH	NEUROD4 MLXIP MLXIPL USF3 NEUROD1 NEUROD2 NEUROD6	1.85e-05	111	138	7	PF00010
Domain	RCC1/BLIP-II	TECPR2 RCBTB1 HERC3 RPGR	2.27e-05	23	138	4	IPR009091
Domain	HLH	NEUROD4 MLXIP MLXIPL USF3 NEUROD1 NEUROD2 NEUROD6	2.46e-05	116	138	7	SM00353
Domain	BHLH	NEUROD4 MLXIP MLXIPL USF3 NEUROD1 NEUROD2 NEUROD6	2.60e-05	117	138	7	PS50888
Domain	bHLH_dom	NEUROD4 MLXIP MLXIPL USF3 NEUROD1 NEUROD2 NEUROD6	2.75e-05	118	138	7	IPR011598
Domain	-	NOL11 BBS2 BRWD3 WDR19 FZR1 TECPR2 NBEAL2 TLE6 IFT122 PHIP PLXNA2	3.77e-05	333	138	11	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	NOL11 BBS2 BRWD3 WDR19 FZR1 TECPR2 NBEAL2 TLE6 IFT122 PHIP PLXNA2	3.98e-05	335	138	11	IPR015943
Domain	WD40_repeat_dom	NOL11 BBS2 BRWD3 WDR19 FZR1 TECPR2 NBEAL2 TLE6 IFT122 PHIP	7.32e-05	297	138	10	IPR017986
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	8.27e-05	12	138	3	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	8.27e-05	12	138	3	IPR027970
Domain	ANF_lig-bd_rcpt	GRIK1 GRIK2 GRIK3 GABBR1	1.56e-04	37	138	4	IPR001828
Domain	ANF_receptor	GRIK1 GRIK2 GRIK3 GABBR1	1.56e-04	37	138	4	PF01094
Domain	-	NEUROD4 MLXIP MLXIPL NEUROD1 NEUROD2 NEUROD6	1.58e-04	109	138	6	4.10.280.10
Domain	Peripla_BP_I	GRIK1 GRIK2 GRIK3 GABBR1	1.92e-04	39	138	4	IPR028082
Domain	Lig_chan-Glu_bd	GRIK1 GRIK2 GRIK3	2.97e-04	18	138	3	PF10613
Domain	Glu/Gly-bd	GRIK1 GRIK2 GRIK3	2.97e-04	18	138	3	IPR019594
Domain	Lig_chan-Glu_bd	GRIK1 GRIK2 GRIK3	2.97e-04	18	138	3	SM00918
Domain	Iontro_rcpt	GRIK1 GRIK2 GRIK3	2.97e-04	18	138	3	IPR001320
Domain	Iono_rcpt_met	GRIK1 GRIK2 GRIK3	2.97e-04	18	138	3	IPR001508
Domain	Lig_chan	GRIK1 GRIK2 GRIK3	2.97e-04	18	138	3	PF00060
Domain	PBPe	GRIK1 GRIK2 GRIK3	2.97e-04	18	138	3	SM00079
Domain	Lep_receptor_Ig	IL12RB2 IL6ST	3.22e-04	4	138	2	PF06328
Domain	IgC2-like_lig-bd	IL12RB2 IL6ST	3.22e-04	4	138	2	IPR010457
Domain	RCC1	RCBTB1 HERC3 RPGR	4.10e-04	20	138	3	PF00415
Domain	RCC1_1	RCBTB1 HERC3 RPGR	4.76e-04	21	138	3	PS00625
Domain	RCC1_2	RCBTB1 HERC3 RPGR	4.76e-04	21	138	3	PS00626
Domain	RCC1_3	RCBTB1 HERC3 RPGR	4.76e-04	21	138	3	PS50012
Domain	-	RCBTB1 HERC3 RPGR	5.48e-04	22	138	3	2.130.10.30
Domain	Reg_chr_condens	RCBTB1 HERC3 RPGR	5.48e-04	22	138	3	IPR000408
Domain	WD40	BRWD3 WDR19 FZR1 TECPR2 NBEAL2 TLE6 IFT122 PHIP	8.62e-04	268	138	8	SM00320
Domain	WD40_repeat	BRWD3 WDR19 FZR1 TECPR2 NBEAL2 TLE6 IFT122 PHIP	9.49e-04	272	138	8	IPR001680
Domain	WD_REPEATS_1	BRWD3 WDR19 FZR1 TECPR2 NBEAL2 TLE6 IFT122 PHIP	1.09e-03	278	138	8	PS00678
Domain	Pre-SET	SETDB1 SETDB2	1.11e-03	7	138	2	PF05033
Domain	PreSET	SETDB1 SETDB2	1.11e-03	7	138	2	SM00468
Domain	Hematopoietin_rcpt_Gp130_CS	IL12RB2 IL6ST	1.11e-03	7	138	2	IPR003529
Domain	Pre-SET_dom	SETDB1 SETDB2	1.11e-03	7	138	2	IPR007728
Domain	PRE_SET	SETDB1 SETDB2	1.11e-03	7	138	2	PS50867
Domain	WD_REPEATS_2	BRWD3 WDR19 FZR1 TECPR2 NBEAL2 TLE6 IFT122 PHIP	1.12e-03	279	138	8	PS50082
Domain	WD_REPEATS_REGION	BRWD3 WDR19 FZR1 TECPR2 NBEAL2 TLE6 IFT122 PHIP	1.12e-03	279	138	8	PS50294
Domain	HEMATOPO_REC_L_F2	IL12RB2 IL6ST	1.47e-03	8	138	2	PS01353
Domain	FN3	IL12RB2 PRTG OBSCN ROS1 MDGA1 IL6ST	2.54e-03	185	138	6	SM00060
Domain	IL6Ra-bind	IL12RB2 IL6ST	2.85e-03	11	138	2	PF09240
Domain	MBD	SETDB1 SETDB2	2.85e-03	11	138	2	SM00391
Domain	MBD	SETDB1 SETDB2	2.85e-03	11	138	2	PS50982
Domain	Methyl_CpG_DNA-bd	SETDB1 SETDB2	2.85e-03	11	138	2	IPR001739
Domain	MBD	SETDB1 SETDB2	2.85e-03	11	138	2	PF01429
Domain	DNA-bd_dom	SETDB1 SETDB2	2.85e-03	11	138	2	IPR016177
Domain	TypeI_recpt_CBD	IL12RB2 IL6ST	2.85e-03	11	138	2	IPR015321
Domain	WD40	BRWD3 WDR19 FZR1 NBEAL2 TLE6 IFT122 PHIP	3.16e-03	259	138	7	PF00400
Domain	FN3	IL12RB2 PRTG OBSCN ROS1 MDGA1 IL6ST	3.65e-03	199	138	6	PS50853
Domain	-	IL12RB2 PRTG OBSCN VSIR ROS1 SIGLEC1 IL1R1 MDGA1 NFAT5 GPA33 PLXNA2 IL6ST	3.77e-03	663	138	12	2.60.40.10
Domain	FN3_dom	IL12RB2 PRTG OBSCN ROS1 MDGA1 IL6ST	4.63e-03	209	138	6	IPR003961
Domain	SEA	TMPRSS11D AGRN	4.65e-03	14	138	2	SM00200
Domain	-	TMPRSS11D AGRN	5.34e-03	15	138	2	3.30.70.960
Domain	PROTEIN_KINASE_TYR	ABL2 OBSCN SYK ROS1	5.82e-03	97	138	4	PS00109
Domain	Tyr_kinase_AS	ABL2 OBSCN SYK ROS1	5.82e-03	97	138	4	IPR008266
Domain	Ig-like_fold	IL12RB2 PRTG OBSCN VSIR ROS1 SIGLEC1 IL1R1 MDGA1 NFAT5 GPA33 PLXNA2 IL6ST	6.16e-03	706	138	12	IPR013783
Domain	-	TG SPOCK3	6.85e-03	17	138	2	4.10.800.10
Domain	Thyroglobulin_1	TG SPOCK3	6.85e-03	17	138	2	IPR000716
Domain	THYROGLOBULIN_1_1	TG SPOCK3	6.85e-03	17	138	2	PS00484
Domain	TY	TG SPOCK3	6.85e-03	17	138	2	SM00211
Domain	THYROGLOBULIN_1_2	TG SPOCK3	6.85e-03	17	138	2	PS51162
Domain	Thyroglobulin_1	TG SPOCK3	6.85e-03	17	138	2	PF00086
Domain	fn3	IL12RB2 PRTG OBSCN ROS1 IL6ST	7.10e-03	162	138	5	PF00041
Pathway	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	GRIK1 GRIK2 GRIK3	3.89e-05	10	99	3	M10272
Pathway	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	GRIK1 GRIK2 GRIK3	7.06e-05	12	99	3	MM15142
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	USP53 AIMP2 ANK3 KIAA0232 RNF144A OBSCN GRIK1 GRIK2 ZMIZ1 ZHX2 NAALADL2 BRWD3 LRCH3 THADA USF3 TECPR2 CBFA2T2 NAXD SCP2 ANKRD17 IFT122 SPIDR NFAT5 GPA33	1.15e-08	1489	144	24	28611215
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HIPK1 KIAA0232 R3HDM2 MLXIP ZHX2 ZCCHC14 SETDB1 MROH1 TLN1 HERC3 NFAT5 PLXNA2 ARAP2	1.68e-08	407	144	13	12693553
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KDM3A PMS2 ZBTB38 ANK3 HIPK1 ADGRB3 APBB3 CCT7 GRIK1 BRWD3 ME3 WDR19 PPP4R3B CRYL1 SETDB1 FBN1 NEUROD2 DST RCBTB1 IFT122 ANKRD36 NEUROD6	1.74e-08	1285	144	22	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP53 KDM3A VWA8 PHRF1 KIF16B ADGRB3 LRCH1 WDR19 PPP4R3B DST TECPR2 NBEAL2 ANKRD17 CEP126	4.84e-08	529	144	14	14621295
Pubmed	The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain.	GRIK1 GRIK2 GRIK3	6.95e-08	3	144	3	31513786
Pubmed	Kainate receptor-mediated responses in the CA1 field of wild-type and GluR6-deficient mice.	GRIK1 GRIK2 GRIK3	6.95e-08	3	144	3	9880586
Pubmed	Differential trafficking of GluR7 kainate receptor subunit splice variants.	GRIK1 GRIK2 GRIK3	6.95e-08	3	144	3	15805114
Pubmed	Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.	NEUROD4 NEUROD1 NEUROD2 NEUROD6	2.73e-07	14	144	4	18160702
Pubmed	Kainate receptors and rhythmic activity in neuronal networks: hippocampal gamma oscillations as a tool.	GRIK1 GRIK2 GRIK3	2.77e-07	4	144	3	15513934
Pubmed	Kainate receptors act as conditional amplifiers of spike transmission at hippocampal mossy fiber synapses.	GRIK1 GRIK2 GRIK3	2.77e-07	4	144	3	19369569
Pubmed	Genetic mapping of four mouse bHLH genes related to Drosophila proneural gene atonal.	NEUROD4 NEUROD2 NEUROD6	2.77e-07	4	144	3	8938455
Pubmed	NeuroD factors regulate cell fate and neurite stratification in the developing retina.	NEUROD1 NEUROD2 NEUROD6	2.77e-07	4	144	3	21593321
Pubmed	Synaptic activation of kainate receptors gates presynaptic CB(1) signaling at GABAergic synapses.	GRIK1 GRIK2 NEUROD6	2.77e-07	4	144	3	20081851
Pubmed	Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice.	GRIK1 GRIK2 GRIK3	2.77e-07	4	144	3	30241548
Pubmed	Developmental expression patterns of kainate receptors in the mouse spinal cord.	GRIK1 GRIK2 GRIK3	6.91e-07	5	144	3	23076118
Pubmed	Kainate receptors: pharmacology, function and therapeutic potential.	GRIK1 GRIK2 GRIK3	6.91e-07	5	144	3	18793656
Pubmed	Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn.	GRIK1 GRIK2 GRIK3	6.91e-07	5	144	3	12223554
Pubmed	Molecular determinants of kainate receptor trafficking.	GRIK1 GRIK2 GRIK3	6.91e-07	5	144	3	18358623
Pubmed	Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.	GRIK1 GRIK2 GRIK3	6.91e-07	5	144	3	28228252
Pubmed	Development of laminar distributions of kainate receptors in the somatosensory cortex of mice.	GRIK1 GRIK2 GRIK3	6.91e-07	5	144	3	9593973
Pubmed	Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains.	GRIK1 GRIK2 GRIK3	6.91e-07	5	144	3	29058671
Pubmed	A human MAP kinase interactome.	USP53 RANBP2 ABL2 ANK3 HIPK1 KIAA0232 SETDB1 USF3 DST SIMC1 ANKRD17 ZHX1	9.49e-07	486	144	12	20936779
Pubmed	Neurogenin 2 has an essential role in development of the dentate gyrus.	NEUROD4 GRIK2 NEUROD1 NEUROD6	1.04e-06	19	144	4	18448566
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A5	1.38e-06	6	144	3	20850414
Pubmed	N-glycan content modulates kainate receptor functional properties.	GRIK1 GRIK2 GRIK3	1.38e-06	6	144	3	28714086
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A5	1.38e-06	6	144	3	25930072
Pubmed	Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses.	GRIK1 GRIK2 GRIK3	2.40e-06	7	144	3	17428973
Pubmed	Glutamate receptors in cortical plasticity: molecular and cellular biology.	GRIK1 GRIK2 GRIK3	2.40e-06	7	144	3	9016303
Pubmed	Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis.	GRIK1 GRIK2 GRIK3	2.40e-06	7	144	3	19342380
Pubmed	Glutamate receptors: brain function and signal transduction.	GRIK1 GRIK2 GRIK3	2.40e-06	7	144	3	9651535
Pubmed	Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.	GRIK1 GRIK2 GRIK3	2.40e-06	7	144	3	1310861
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A5 CRB1	2.81e-06	24	144	4	32212159
Pubmed	Transmembrane topology of the glutamate receptor subunit GluR6.	GRIK1 GRIK2 GRIK3	3.83e-06	8	144	3	8163463
Pubmed	Survival of a Novel Subset of Midbrain Dopaminergic Neurons Projecting to the Lateral Septum Is Dependent on NeuroD Proteins.	NEUROD1 NEUROD2 NEUROD6	5.73e-06	9	144	3	28130357
Pubmed	Expression of glutamate receptor subunit genes during development of the mouse retina.	GRIK1 GRIK2 GRIK3	5.73e-06	9	144	3	9051806
Pubmed	In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development.	NEUROD1 NEUROD6 PLXNA2	1.49e-05	12	144	3	21300888
Pubmed	Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice.	GRIK1 GRIK2	1.70e-05	2	144	2	15673679
Pubmed	Association of markers in the 3' region of the GluR5 kainate receptor subunit gene to alcohol dependence.	GRIK1 GRIK3	1.70e-05	2	144	2	19320626
Pubmed	Neuronal basic helix-loop-helix proteins (NEX, neuroD, NDRF): spatiotemporal expression and targeted disruption of the NEX gene in transgenic mice.	NEUROD2 NEUROD6	1.70e-05	2	144	2	9454850
Pubmed	Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming.	SETDB1 SETDB2	1.70e-05	2	144	2	30850015
Pubmed	Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus.	GRIK1 GRIK2	1.70e-05	2	144	2	11182092
Pubmed	The proneural genes NEUROD1 and NEUROD2 are expressed during human trophoblast invasion.	NEUROD1 NEUROD2	1.70e-05	2	144	2	11900979
Pubmed	Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit.	GRIK1 GRIK2	1.70e-05	2	144	2	14724198
Pubmed	GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses.	GRIK2 GRIK3	1.70e-05	2	144	2	17620617
Pubmed	The kainate receptor subunit GluR6 mediates metabotropic regulation of the slow and medium AHP currents in mouse hippocampal neurones.	GRIK1 GRIK2	1.70e-05	2	144	2	15539395
Pubmed	RNA editing of human kainate receptor subunits.	GRIK1 GRIK2	1.70e-05	2	144	2	7696618
Pubmed	Atypical functional properties of GluK3-containing kainate receptors.	GRIK2 GRIK3	1.70e-05	2	144	2	20007474
Pubmed	Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.	GRIK1 GRIK2	1.70e-05	2	144	2	8260617
Pubmed	Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.	GRIK1 GRIK2	1.70e-05	2	144	2	15537878
Pubmed	MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells.	MLXIP MLXIPL	1.70e-05	2	144	2	29282201
Pubmed	t(4;8)(q27;q24) in Hodgkin lymphoma cells targets phosphodiesterase PDE5A and homeobox gene ZHX2.	ZHX2 PDE5A	1.70e-05	2	144	2	21987443
Pubmed	Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder.	GRIK2 GRIK3	1.70e-05	2	144	2	15094479
Pubmed	Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice.	RICTOR FBN1	1.70e-05	2	144	2	30004239
Pubmed	Postnatal maturation of mossy fibre excitatory transmission in mouse CA3 pyramidal cells: a potential role for kainate receptors.	GRIK1 GRIK2	1.70e-05	2	144	2	15358807
Pubmed	Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene.	PMS2 AIMP2	1.70e-05	2	144	2	8666379
Pubmed	Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis.	GRIK1 GRIK2	1.70e-05	2	144	2	24760837
Pubmed	NFAT5 regulates transcription of the mouse telomerase reverse transcriptase gene.	TERT NFAT5	1.70e-05	2	144	2	20937271
Pubmed	Identification of the kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus.	GRIK1 GRIK2	1.70e-05	2	144	2	11069933
Pubmed	Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation.	GRIK1 GRIK2	1.70e-05	2	144	2	12947409
Pubmed	Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module.	MLXIP MLXIPL	1.70e-05	2	144	2	16644671
Pubmed	Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex.	GRIK1 GRIK2	1.70e-05	2	144	2	15928066
Pubmed	Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.	GRIK1 GRIK2	1.70e-05	2	144	2	8700852
Pubmed	Contrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes.	MLXIP MLXIPL	1.70e-05	2	144	2	26910886
Pubmed	Q/R site editing controls kainate receptor inhibition by membrane fatty acids.	GRIK1 GRIK2	1.70e-05	2	144	2	16221857
Pubmed	Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice.	GRIK1 GRIK2	1.70e-05	2	144	2	16219388
Pubmed	Subunit composition and alternative splicing regulate membrane delivery of kainate receptors.	GRIK1 GRIK2	1.70e-05	2	144	2	15014126
Pubmed	Subunit composition of kainate receptors in hippocampal interneurons.	GRIK1 GRIK2	1.70e-05	2	144	2	11144357
Pubmed	Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus.	NEUROD1 NEUROD6	1.70e-05	2	144	2	10804213
Pubmed	Contribution of aberrant GluK2-containing kainate receptors to chronic seizures in temporal lobe epilepsy.	GRIK1 GRIK2	1.70e-05	2	144	2	25043179
Pubmed	NeuroD2 controls inhibitory circuit formation in the molecular layer of the cerebellum.	NEUROD1 NEUROD2	1.70e-05	2	144	2	30723302
Pubmed	A mosaic of functional kainate receptors in hippocampal interneurons.	GRIK1 GRIK2	1.70e-05	2	144	2	15483117
Pubmed	Functional characterization of kainate receptors in the mouse nucleus accumbens.	GRIK1 GRIK2	1.70e-05	2	144	2	11985817
Pubmed	Targeted disruption of NeuroD, a proneural basic helix-loop-helix factor, impairs distal lung formation and neuroendocrine morphology in the neonatal lung.	FBN1 NEUROD1	1.70e-05	2	144	2	18339630
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	VWA8 ZMIZ1 SETDB1 DST NFAT5 PLXNA2	1.77e-05	130	144	6	12421765
Pubmed	Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.	GRIK1 GRIK2 GRIK3	1.93e-05	13	144	3	20859245
Pubmed	A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2.	IL13 SETDB2 RCBTB1	2.45e-05	14	144	3	20085599
Pubmed	COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression.	NEUROD1 NEUROD2 NEUROD6	2.45e-05	14	144	3	21965613
Pubmed	Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.	PRTG MLXIP ME3 CRYL1 ARAP2	2.85e-05	85	144	5	23648065
Pubmed	A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex.	NEUROD1 NEUROD2 NEUROD6	4.53e-05	17	144	3	17694053
Pubmed	Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor.	GRIK1 GRIK2	5.09e-05	3	144	2	27346345
Pubmed	Cloning and functional expression of a cDNA encoding the mouse beta 2 subunit of the kainate-selective glutamate receptor channel.	GRIK1 GRIK2	5.09e-05	3	144	2	1379666
Pubmed	Effect of RNA editing and subunit co-assembly single-channel properties of recombinant kainate receptors.	GRIK1 GRIK2	5.09e-05	3	144	2	8730589
Pubmed	Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing.	TERT ROS1	5.09e-05	3	144	2	27153396
Pubmed	TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion.	MLXIP MLXIPL	5.09e-05	3	144	2	31782782
Pubmed	Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic thyroid carcinoma tissues and cell lines.	TERT TG	5.09e-05	3	144	2	17671725
Pubmed	Coupling of β2 integrins to actin by a mechanosensitive molecular clutch drives complement receptor-mediated phagocytosis.	TLN1 SYK	5.09e-05	3	144	2	31659275
Pubmed	Expression and prognostic significance of zinc fingers and homeoboxes family members in renal cell carcinoma.	ZHX2 ZHX1	5.09e-05	3	144	2	28152006
Pubmed	Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression.	TERT FBN1	5.09e-05	3	144	2	24401839
Pubmed	Supervillin binding to myosin II and synergism with anillin are required for cytokinesis.	ANLN SVIL	5.09e-05	3	144	2	24088567
Pubmed	Telomere dysfunction activates YAP1 to drive tissue inflammation.	LGR5 TERT	5.09e-05	3	144	2	32958778
Pubmed	Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor.	ZHX2 ZHX1	5.09e-05	3	144	2	12741956
Pubmed	Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia.	SETDB2 RCBTB1	5.09e-05	3	144	2	11306461
Pubmed	Induction of pancreatic islet cell differentiation by the neurogenin-neuroD cascade.	NEUROD1 NEUROD2	5.09e-05	3	144	2	17924961
Pubmed	Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca2+ pathways in human osteoarthritis osteoblasts.	WNT5A LGR5	5.09e-05	3	144	2	28777797
Pubmed	Recurrent chromosomal rearrangements of ROS1, FRK and IL6 activating JAK/STAT pathway in inflammatory hepatocellular adenomas.	ROS1 IL6ST	5.09e-05	3	144	2	31907296
Pubmed	ARID1A-SIN3A drives retinoic acid-induced neuroblastoma differentiation by transcriptional repression of TERT.	SIN3A TERT	5.09e-05	3	144	2	31365169
Pubmed	RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue.	GRIK1 GRIK2	5.09e-05	3	144	2	7523595
Pubmed	Molecular basis of functional exchangeability between ezrin and other actin-membrane associated proteins during cytokinesis.	ANLN SVIL	5.09e-05	3	144	2	33862101
Pubmed	A transgenic insertional inner ear mutation on mouse chromosome 1.	DST IL1R1	5.09e-05	3	144	2	10763993
Pubmed	NFX1 interacts with mSin3A/histone deacetylase to repress hTERT transcription in keratinocytes.	SIN3A TERT	5.09e-05	3	144	2	18505829
Cytoband	Ensembl 112 genes in cytogenetic band chr8q24	ZHX2 FBXL6 TG MAL2 MROH1 TONSL ZHX1	1.38e-04	355	144	7	chr8q24
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	2.70e-04	8	144	2	chr9q12
GeneFamily	Glutamate ionotropic receptor kainate type subunits	GRIK1 GRIK2 GRIK3	1.49e-06	5	97	3	1199
GeneFamily	Basic helix-loop-helix proteins	NEUROD4 MLXIP MLXIPL NEUROD1 NEUROD2 NEUROD6	2.79e-05	110	97	6	420
GeneFamily	WD repeat domain containing	BRWD3 WDR19 FZR1 NBEAL2 TLE6 IFT122 PHIP	5.25e-04	262	97	7	362
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL12RB2 IL1R1 IL6ST	1.48e-03	42	97	3	602
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	SETDB1 SETDB2	1.52e-03	11	97	2	1025
GeneFamily	Fibronectin type III domain containing	IL12RB2 PRTG OBSCN ROS1 IL6ST	1.71e-03	160	97	5	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PRTG OBSCN SIGLEC1 IL1R1 MDGA1	1.75e-03	161	97	5	593
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZHX2 ZHX1	2.86e-03	15	97	2	529
Coexpression	ZHONG_PFC_MAJOR_TYPES_EXCITATORY_NEURON	NEUROD1 NEUROD2 NEUROD6	8.37e-06	8	141	3	M39075
Coexpression	GSE33162_HDAC3_KO_VS_HDAC3_KO_4H_LPS_STIM_MACROPHAGE_UP	USP53 PMS2 GPX2 KIF16B SIN3A MLXIP RCBTB1 ANKRD17	1.33e-05	200	141	8	M9041
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	TRPM6 ANK3 VWA8 LRCH1 NAALADL2 ME3 DST SVIL	1.76e-05	208	141	8	M39233
Coexpression	NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON	ZHX2 FBXL6 TG MAL2 MROH1 TONSL ZHX1	2.34e-05	157	141	7	M17936
Coexpression	GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN	TRPM6 ZHX2 DST SCP2 HERC3 IL1R1 GABBR1	5.39e-05	179	141	7	M6689
Coexpression	PARENT_MTOR_SIGNALING_UP	EFL1 PMS2 DCTN5 ME3 CRYL1 THADA TECPR2 SVIL IFT122 RPGR IL1R1 NCKAP1L	5.93e-05	567	141	12	M16909
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	KDM3A RANBP2 WNT5A R3HDM2 ZMIZ1 ZHX2 SETDB1 DST MTFR1 ANKRD17 RPGR SPIDR IL1R1 PHIP ARAP2	6.08e-05	856	141	15	M4500
Coexpression	GSE26023_PHD3_KO_VS_WT_NEUTROPHIL_HYPOXIA_UP	TRPM6 USP53 GRIK2 ADAMTS13 MLXIP PTPRN AGRN	1.02e-04	198	141	7	M8146
Coexpression	GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN	RANBP2 ABL2 DSG1 SLC19A2 SETDB2 KIAA0825 PLXNA2	1.02e-04	198	141	7	M9346
Coexpression	GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP	GPX2 GRIK1 BRWD3 TLN1 NEUROD6 AGRN GABBR1	1.02e-04	198	141	7	M3596
Coexpression	GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP	APBB3 NOL11 BBS2 ZCCHC14 ANKRD36 GPA33 IL6ST	1.02e-04	198	141	7	M3108
Coexpression	GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN	RICTOR SIN3A MLXIP SYK ELF2 PHIP NCKAP1L	1.08e-04	200	141	7	M5851
Coexpression	GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP	SP4 PHRF1 RCVRN BRWD3 MROH1 AGRN GABBR1	1.08e-04	200	141	7	M3587
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN	RNF144A RRM1 PPP4R3B MTFR1 TLN1 SVIL SPIDR	1.08e-04	200	141	7	M8485
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	ANK3 NEUROD4 ADGRB3 GRIK2 GRIK3 OTOGL RPGR ARAP2	8.79e-08	173	142	8	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	CTRL-Myeloid-Alveolar_Macrophage\|Myeloid / Disease state, Lineage and Cell class	VWA8 KIF16B STAC DST SVIL SCP2 SPIDR NCKAP1L	2.04e-07	193	142	8	80871d963c23a6befe58e5e60b7f7d1a1b227ce2
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRTG ABCA13 SLC26A5 CRB1 OTOGL TMPRSS11D ROS1	4.32e-07	145	142	7	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 RNF144A ADGRB3 GRIK2 TG SPOCK3 CDH7	8.74e-07	161	142	7	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRTG ABCA13 OTOGL SPOCK3 TMPRSS11D ROS1 SIGLEC1	9.11e-07	162	142	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT5A MAL2 SETDB2 NBEAL2 PDE5A SPIDR PLXNA2	1.03e-06	165	142	7	7c771f22b58989572c939ed127e637ec28dc0dca
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	ANK3 ADGRB3 BBS2 GRIK2 GRIK3 RPGR ARAP2	1.03e-06	165	142	7	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK3 ADGRB3 GRIK2 GRIK3 DST OTOGL RPGR	1.16e-06	168	142	7	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	ILEUM-inflamed-(9)_Enteric_neurons\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANK3 ADGRB3 GRIK2 GRIK3 DDX11 DST OTOGL	1.71e-06	178	142	7	d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCell	ILEUM-inflamed-(9)_Neuro_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANK3 ADGRB3 GRIK2 GRIK3 DDX11 DST OTOGL	1.71e-06	178	142	7	611504b0a9e6318b18fba83787b03f9245c82252
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RNF144A SLC19A2 STAC DST SVIL IL1R1 IL6ST	1.98e-06	182	142	7	b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RANBP2 HIPK1 RICTOR ANKRD36 NFAT5 IL6ST ARAP2	2.46e-06	188	142	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Severe_COVID-19-Myeloid-proliferating_Myeloid_cells\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	WNT5A ADGRB3 RRM1 STAC DST ANLN GPA33	2.92e-06	193	142	7	0d85025690c9cd545cba30abc38acbdd6a39b153
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRTG GRIK1 GRIK2 GRIK3 LGR5 SPOCK3 CDH7	2.92e-06	193	142	7	e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WNT5A ADGRB3 RRM1 STAC DST ANLN GPA33	3.02e-06	194	142	7	cb39850e9577015b6b9834e98c36b412bae7d462
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WNT5A ADGRB3 RRM1 STAC DST ANLN GPA33	3.02e-06	194	142	7	408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	WNT5A ADGRB3 RRM1 STAC DST ANLN GPA33	3.02e-06	194	142	7	193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WNT5A ADGRB3 RRM1 STAC DST ANLN GPA33	3.02e-06	194	142	7	2360b5f995b360419de41612368cab9fb61781a1
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	WNT5A ADGRB3 RRM1 STAC DST ANLN GPA33	3.02e-06	194	142	7	903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	WNT5A ADGRB3 RRM1 STAC DST ANLN GPA33	3.02e-06	194	142	7	58406502a8cbcc3037f79a1b6a683df408297ae5
ToppCell	CTRL-Myeloid-Alveolar_Macrophage\|CTRL / Disease state, Lineage and Cell class	VWA8 KIF16B STAC DST SVIL SPIDR NCKAP1L	3.02e-06	194	142	7	be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBTB38 GPX2 MLXIP LGR5 MAL2 C9orf152 MLXIPL	3.13e-06	195	142	7	b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PRTG GRIK1 GRIK2 GRIK3 SPOCK3 ANKRD36 CDH7	3.70e-06	200	142	7	a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PRTG GRIK1 GRIK2 GRIK3 SPOCK3 ANKRD36 CDH7	3.70e-06	200	142	7	33b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PRTG GRIK1 GRIK2 GRIK3 SPOCK3 ANKRD36 CDH7	3.70e-06	200	142	7	9719fabddc34051949468a7520289e3c750de4f8
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 NEUROD1 NEUROD2 CBFA2T2 NEUROD6 PLXNA2	1.09e-05	156	142	6	7e6805ebc7bc2f9c5965321d16922c155719970f
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RANBP2 ANK3 HIPK1 RICTOR ANKRD36 IL6ST	1.09e-05	156	142	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 NEUROD1 NEUROD2 CBFA2T2 NEUROD6 PLXNA2	1.09e-05	156	142	6	741de05295b2d012ac8576378f37709a97c8fb50
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	GRIK2 VSIR DST NBEAL2 MDGA1 AGRN	1.26e-05	160	142	6	58ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	POU5F2 MTFR1 CBFA2T2 NAXD ROS1 CEP126	1.56e-05	166	142	6	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	PMS2 HIPK1 OBSCN WDR19 USF3 SLFNL1	1.56e-05	166	142	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	LA-16._Neuronal\|World / Chamber and Cluster_Paper	ANK3 ADGRB3 GRIK2 GRIK3 RPGR ARAP2	1.67e-05	168	142	6	2fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCell	LA-16._Neuronal\|LA / Chamber and Cluster_Paper	ANK3 ADGRB3 GRIK2 GRIK3 RPGR ARAP2	1.67e-05	168	142	6	c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	ANK3 ADGRB3 GRIK2 GRIK3 RPGR ARAP2	1.72e-05	169	142	6	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	OBSCN TG SYK SIGLEC1 GPA33 NCKAP1L	1.78e-05	170	142	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	USP53 RNF144A STAC DST SPOCK3 IL1R1	1.78e-05	170	142	6	6c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA8 POU5F2 SLC19A2 ADAMTS13 FBN1 PDE5A	1.97e-05	173	142	6	a37f38478473290fe35aea8684befc3bf95b161f
ToppCell	CF-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	FBXL13 TG KIAA0825 TECPR2 SVIL IL1R1	2.10e-05	175	142	6	8020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCell	RSV-Healthy-2\|Healthy / Virus stimulation, Condition and Cluster	RRM1 LRCH1 CRYL1 KIAA0825 ANLN ZHX1	2.10e-05	175	142	6	c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCell	RSV-Healthy-2\|RSV / Virus stimulation, Condition and Cluster	RRM1 LRCH1 CRYL1 KIAA0825 ANLN ZHX1	2.10e-05	175	142	6	0e97189585b7afaf3bd622c3ef10c86412393829
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SP4 ABL2 APBB3 ZHX2 SIGLEC1 NFAT5	2.24e-05	177	142	6	f28243b51be104cb3adcde63f03fc2206ed3121e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	POU5F2 SPATA31A7 NAALADL2 FBXL6 NEUROD2 SVIL	2.46e-05	180	142	6	81d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB38 VWA8 SLC19A2 ADAMTS13 FBN1 PDE5A	2.62e-05	182	142	6	be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB38 VWA8 SLC19A2 ADAMTS13 FBN1 PDE5A	2.62e-05	182	142	6	74dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCell	CF-Myeloid-Neutrophil\|CF / Disease state, Lineage and Cell class	FBXL13 TG KIAA0825 TECPR2 SVIL IL1R1	2.70e-05	183	142	6	da43827952e6fdee2ce94648c316182f272b321c
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RNF144A STAC DST SVIL IL1R1 IL6ST	2.96e-05	186	142	6	855c2e5a8a6cf94c7de31982e0e2416f924439d3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK1 GRIK2 GRIK3 QRFPR SPOCK3 CDH7	3.05e-05	187	142	6	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	droplet-Thymus-nan-18m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXL13 ANK3 GRIK3 MAL2 SPOCK3 AGRN	3.05e-05	187	142	6	ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|368C / Donor, Lineage, Cell class and subclass (all cells)	C9orf152 SIMC1 TLE6 PDE5A ROS1 AGRN	3.05e-05	187	142	6	b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	C9orf152 SIMC1 TLE6 PDE5A ROS1 AGRN	3.05e-05	187	142	6	61c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MLXIPL NEUROD1 DST PTPRN PDE5A IL1R1	3.14e-05	188	142	6	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 ANK3 KIF16B SLC19A2 CRYL1 PLXNA2	3.23e-05	189	142	6	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MLXIPL NEUROD1 DST PTPRN PDE5A IL1R1	3.43e-05	191	142	6	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEUROD4 ADGRB3 GRIK2 GRIK3 STAC CRB1	3.43e-05	191	142	6	c7b95a5f9185d533c08754ce2e4ce91533eb612e
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MLXIPL NEUROD1 DST PTPRN PDE5A IL1R1	3.43e-05	191	142	6	a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MLXIPL NEUROD1 DST PTPRN PDE5A IL1R1	3.53e-05	192	142	6	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 ANK3 HIPK1 ANKRD36 IL6ST ARAP2	3.53e-05	192	142	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	ZMIZ1 STAC DST SPOCK3 SVIL IL1R1	3.53e-05	192	142	6	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEUROD4 ADGRB3 GRIK2 GRIK3 STAC CRB1	3.53e-05	192	142	6	56f2388c9c4e19883ae5cff332c77f596ff744a8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK1 GRIK2 GRIK3 CRB1 SPOCK3 CDH7	3.64e-05	193	142	6	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	Monocytes-Tissue-resident_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	USP53 WNT5A ADGRB3 MLXIP DST ANKRD36	3.64e-05	193	142	6	198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZHX2 TG ANKRD17 SPIDR NFAT5 IL6ST	3.64e-05	193	142	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0232 MLXIPL NEUROD1 DST MROH1 PTPRN	3.64e-05	193	142	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0232 MLXIPL NEUROD1 DST MROH1 PTPRN	3.64e-05	193	142	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK1 GRIK2 GRIK3 CRB1 QRFPR SPOCK3	3.64e-05	193	142	6	8b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK1 GRIK2 GRIK3 QRFPR SPOCK3 CDH7	3.64e-05	193	142	6	3ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRTG GRIK1 GRIK2 GRIK3 SPOCK3 CDH7	3.64e-05	193	142	6	658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MLXIPL NEUROD1 DST PTPRN PDE5A IL1R1	3.74e-05	194	142	6	92b39a935e8c577eb1123d706d168fa13cf3344c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRTG GRIK1 GRIK2 GRIK3 SPOCK3 CDH7	3.74e-05	194	142	6	1bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCA13 ADGRB3 PKD1L3 NAALADL2 FBN1 OTOGL	3.85e-05	195	142	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCA13 ADGRB3 PKD1L3 NAALADL2 FBN1 OTOGL	3.85e-05	195	142	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	NEUROD4 NEUROD2 CBFA2T2 SVIL PHIP PLXNA2	3.96e-05	196	142	6	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	NEUROD4 NEUROD2 CBFA2T2 SVIL PHIP PLXNA2	3.96e-05	196	142	6	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 NEUROD1 NEUROD2 CBFA2T2 NEUROD6 PLXNA2	4.19e-05	198	142	6	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 NEUROD1 NEUROD2 CBFA2T2 NEUROD6 PLXNA2	4.19e-05	198	142	6	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPX2 MLXIP LGR5 MAL2 C9orf152 MLXIPL	4.19e-05	198	142	6	e8bfae3888b2406b5629b576cb02913b3297337e
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 VWA8 ADGRB3 ZHX2 NAALADL2 SPIDR	4.31e-05	199	142	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABL2 KIF16B SVIL SYK SIGLEC1 NCKAP1L	4.31e-05	199	142	6	fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MAL2 MROH1 ANLN BPIFB2 MDGA1 GABBR1	4.31e-05	199	142	6	f0c289523957258d16135c04679db379d43d28d9
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-C1ql3_(Nucleus_of_the_lateral_olfactory_tract_(LOT))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	RCVRN NEUROD1 NEUROD2 NEUROD6	4.32e-05	61	142	4	a9f5cbbe5683f2574130ffe8d375d693b9aa8f2d
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-C1ql3_(Nucleus_of_the_lateral_olfactory_tract_(LOT))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	RCVRN NEUROD1 NEUROD2 NEUROD6	4.32e-05	61	142	4	3797e1e122818211664847bb54730034af61430e
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GRIK1 GRIK2 GRIK3 CRB1 QRFPR SPOCK3	4.43e-05	200	142	6	858421b91f5207b7934b5c219752cb9322a3da31
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-OPC_related\|5w / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 ME3 CRB1 NEUROD1 NEUROD2 CDH7	4.43e-05	200	142	6	b19a75d4f23e9685cbb6c6fa873d7726f27bd5f2
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-LGR5--L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PRTG GRIK1 GRIK2 LGR5 SPOCK3 SVIL	4.43e-05	200	142	6	8c1d4fffa5abe89ee2ff84fed2dfa97c779bde04
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-LGR5-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PRTG GRIK1 GRIK2 LGR5 SPOCK3 SVIL	4.43e-05	200	142	6	1026b4ede4ea61d01ea942164b37a08c8c8234ff
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GRIK1 GRIK2 GRIK3 LGR5 SPOCK3 CDH7	4.43e-05	200	142	6	6a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GRIK1 GRIK2 GRIK3 CRB1 QRFPR SPOCK3	4.43e-05	200	142	6	a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GRIK1 GRIK2 GRIK3 LGR5 SPOCK3 CDH7	4.43e-05	200	142	6	8d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 NEUROD1 NEUROD2 HERC3 ANKRD36 NEUROD6	4.43e-05	200	142	6	04699d1149a143b96d6f292c0d70c4d3e6dfc611
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GRIK1 GRIK2 GRIK3 LGR5 SPOCK3 CDH7	4.43e-05	200	142	6	cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GRIK1 GRIK2 GRIK3 CRB1 QRFPR SPOCK3	4.43e-05	200	142	6	2131c8e7fa054b79906eaf60536da892438b09cd
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-OPC_related-Oligodendrocyte/OPC\|5w / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 ME3 CRB1 NEUROD1 NEUROD2 CDH7	4.43e-05	200	142	6	b99dc49b735430a5ac51159575b904020d861927
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-LGR5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PRTG GRIK1 GRIK2 LGR5 SPOCK3 SVIL	4.43e-05	200	142	6	72c9cd872074b60f62685a95eab83c41e609eb6e
ToppCell	facs-Marrow-B-cells-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXL13 TCHHL1 ROS1 ANKRD36 NEUROD6	9.55e-05	143	142	5	6df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS13 MAL2 QRFPR NEUROD1 CDH7	9.55e-05	143	142	5	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	QRFPR NEUROD1 NEUROD2 NEUROD6	9.71e-05	75	142	4	3bc5df14f21c1c93c2a0fd5fc47bc5d146ba87a2
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LGR5 STAC DST SPOCK3 IL1R1	1.05e-04	146	142	5	40fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 QRFPR NEUROD1 NEUROD2 NEUROD6	1.12e-04	148	142	5	a261c6d3d9cf0311c053fca66c37d39e66db6ad8
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 QRFPR NEUROD1 NEUROD2 NEUROD6	1.12e-04	148	142	5	c0237ba7d4040b6a497094b362dfb8b3a97a7d06
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	OBSCN R3HDM2 GRIK3 NEUROD2 NEUROD6	1.20e-04	150	142	5	9d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
Disease	Exudative retinopathy	CRB1 RCBTB1	1.28e-04	4	137	2	C0154832
Disease	Cranioectodermal dysplasia	WDR19 IFT122	1.28e-04	4	137	2	cv:C4551571
Disease	CRANIOECTODERMAL DYSPLASIA 1	WDR19 IFT122	2.12e-04	5	137	2	C0432235
Disease	Plasmodium falciparum malaria (is_marker_for)	IL13 ADAMTS13	2.12e-04	5	137	2	DOID:14067 (is_marker_for)
Disease	Allergic Reaction	IL13 DSG1 IL1R1 IL6ST	2.14e-04	63	137	4	C1527304
Disease	Hypersensitivity	IL13 DSG1 IL1R1 IL6ST	2.28e-04	64	137	4	C0020517
Disease	cleft lip	PRTG ADGRB3 NAALADL2 THADA DST SVIL MDGA1	3.77e-04	284	137	7	EFO_0003959
Disease	Cerebral ventriculomegaly	SIN3A IFT122	4.43e-04	7	137	2	C1531647
Disease	Hydrocephalus Ex-Vacuo	SIN3A IFT122	4.43e-04	7	137	2	C0270720
Disease	Communicating Hydrocephalus	SIN3A IFT122	4.43e-04	7	137	2	C0009451
Disease	Fetal Cerebral Ventriculomegaly	SIN3A IFT122	4.43e-04	7	137	2	C2936718
Disease	Post-Traumatic Hydrocephalus	SIN3A IFT122	4.43e-04	7	137	2	C0477432
Disease	Obstructive Hydrocephalus	SIN3A IFT122	4.43e-04	7	137	2	C0549423
Disease	late-onset Alzheimers disease	ANK3 GRIK2 NAALADL2 C9orf152 FZR1 AGRN CDH7	4.45e-04	292	137	7	EFO_1001870
Disease	Congenital Hydrocephalus	SIN3A IFT122	5.88e-04	8	137	2	C0020256
Disease	Aqueductal Stenosis	SIN3A IFT122	5.88e-04	8	137	2	C2936786
Disease	Hydrocephalus	SIN3A IFT122	7.54e-04	9	137	2	C0020255
Disease	platelet component distribution width	KIAA0232 KIF16B SIN3A ZMIZ1 LRCH1 MLXIPL TLN1 SVIL EIF2B3 SYK SIGLEC1	8.20e-04	755	137	11	EFO_0007984
Disease	refractive error	ZBTB38 ANK3 RD3L FBN1 NEUROD2 RCBTB1 PDE5A	8.51e-04	326	137	7	MONDO_0004892
Disease	valine measurement	ZMIZ1 MLXIP NEUROD6	8.53e-04	40	137	3	EFO_0009792
Disease	retinitis pigmentosa (is_implicated_in)	CRB1 WDR19 RPGR	9.17e-04	41	137	3	DOID:10584 (is_implicated_in)
Disease	postburn hypertrophic scarring severity measurement	DSG1 ARAP2	9.40e-04	10	137	2	EFO_0007747
Disease	response to carboplatin, response to antineoplastic agent	PRTG CRYL1	9.40e-04	10	137	2	GO_0097327, GO_0097328
Disease	1,7-dimethylurate measurement	GRIK2 NAALADL2	9.40e-04	10	137	2	EFO_0021512
Disease	prostate carcinoma	PRTG ZBTB38 ZMIZ1 PKD1L3 TERT C9orf152 THADA ANLN SYK ANKRD36 GPA33 PHIP	9.43e-04	891	137	12	EFO_0001663
Disease	APOE carrier status, cerebral amyloid angiopathy	RNF144A GRIK2 FZR1	9.85e-04	42	137	3	EFO_0006790, EFO_0007659
Disease	Disease Exacerbation	ABCA13 CCT7 RRM1 TERT NAXD	1.06e-03	165	137	5	C0235874
Disease	diastolic blood pressure, systolic blood pressure	EFL1 ANK3 LRCH1 CRB1 PPP4R3B MAL2 FBN1 SVIL NFAT5 GABBR1	1.18e-03	670	137	10	EFO_0006335, EFO_0006336
Disease	attention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia	ANK3 GRIK1 ZMIZ1 IL1R1	1.28e-03	101	137	4	EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Disease	ocular hypertension, response to triamcinolone acetonide	VWA8 GRIK1 OTOGL	1.54e-03	49	137	3	EFO_0006954, EFO_1001069
Disease	Colorectal Carcinoma	PMS2 ABCA13 OBSCN GRIK3 ZMIZ1 LGR5 BPIFB2 CDH7 PHIP IL6ST	1.67e-03	702	137	10	C0009402
Disease	fibrinogen measurement	GRIK2 PKD1L3 IL1R1 PHIP	1.70e-03	109	137	4	EFO_0004623
Disease	Ciliopathies	BBS2 CRB1 WDR19 RPGR	1.76e-03	110	137	4	C4277690
Disease	Bipolar Disorder	SP4 ANK3 DCTN5 ABCA13 GRIK1 GRIK2 MDGA1 CDH7	1.79e-03	477	137	8	C0005586
Disease	multiple sclerosis	ZBTB38 DSG1 VWA8 ZMIZ1 TERT TG RCBTB1 SVIL SYK	1.88e-03	594	137	9	MONDO_0005301
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	EIF2B3 SCP2	1.88e-03	14	137	2	C1858991
Disease	glycodeoxycholate measurement	GRIK2 SVIL	1.88e-03	14	137	2	EFO_0010493
Disease	executive function measurement	ZBTB38 ADGRB3 BBS2 POLR3A LRCH3 SPOCK3 CDH7	1.93e-03	376	137	7	EFO_0009332
Disease	Pneumonia	IL13 IL1R1 IL6ST	2.04e-03	54	137	3	C0032285
Disease	Lobar Pneumonia	IL13 IL1R1 IL6ST	2.04e-03	54	137	3	C0032300
Disease	Pneumonitis	IL13 IL1R1 IL6ST	2.04e-03	54	137	3	C3714636
Disease	Experimental Lung Inflammation	IL13 IL1R1 IL6ST	2.04e-03	54	137	3	C0887898
Disease	refractive error, age at onset, Myopia	ZBTB38 GRIK1 RD3L FBN1 RCBTB1	2.12e-03	193	137	5	EFO_0004847, HP_0000545, MONDO_0004892
Disease	forehead morphology measurement	GRIK1 CDH7	2.16e-03	15	137	2	EFO_0007844
Disease	hypothyroidism	IL12RB2 HIPK1 PHRF1 TERT TG PPP4R3B	2.17e-03	284	137	6	EFO_0004705
Disease	pro-hydroxy-pro measurement	TRPM6 WNT5A	2.46e-03	16	137	2	EFO_0021132
Disease	Dermatitis	IL13 DSG1	2.46e-03	16	137	2	C0011603
Disease	blood osmolality measurement	GRIK2 NAALADL2 NFAT5	2.51e-03	58	137	3	EFO_0007967
Disease	Schizophrenia	SP4 ANK3 ABCA13 GRIK1 GRIK2 GRIK3 SETDB1 RCBTB1 MDGA1 PLXNA2 GABBR1	2.81e-03	883	137	11	C0036341
Disease	mean platelet volume	ZBTB38 KIAA0232 KIF16B SIN3A ZMIZ1 LRCH1 TERT QRFPR MLXIPL SVIL SYK PHIP	2.91e-03	1020	137	12	EFO_0004584
Disease	Adrenocortical carcinoma	RRM1 TERT	3.12e-03	18	137	2	C0206686
Disease	acetone measurement	VWA8 MLXIP	3.47e-03	19	137	2	EFO_0010989
Disease	Usual Interstitial Pneumonia	WNT5A TERT	3.47e-03	19	137	2	C4721509
Disease	Hamman-Rich Disease	WNT5A TERT	3.47e-03	19	137	2	C4721508
Disease	emphysema pattern measurement	VWA8 SVIL	3.47e-03	19	137	2	EFO_0005850
Disease	ovarian neoplasm	PMS2 GRIK2 TERT IL6ST	3.58e-03	134	137	4	C0919267
Disease	platelet measurement	KIAA0232 ZMIZ1 LRCH1 TERT TECPR2 NBEAL2	3.61e-03	315	137	6	EFO_0005036
Disease	response to heparin, antibody measurement	GRIK2 NAALADL2	3.85e-03	20	137	2	EFO_0004556, EFO_0006816
Disease	Familial Idiopathic Pulmonary Fibrosis	WNT5A TERT	3.85e-03	20	137	2	C4721952
Disease	Malignant neoplasm of ovary	PMS2 GRIK2 TERT IL6ST	3.88e-03	137	137	4	C1140680
Disease	neuroimaging measurement	PRTG FBXL13 ANK3 ZHX2 LRCH1 TG MLXIPL THADA NEUROD2 CBFA2T2 PLXNA2 GABBR1	4.23e-03	1069	137	12	EFO_0004346
Disease	Idiopathic Pulmonary Fibrosis	WNT5A TERT	4.24e-03	21	137	2	C1800706
Disease	Malignant neoplasm of liver	GPX2 GRIK2 TERT HERC3	4.40e-03	142	137	4	C0345904
Disease	Liver neoplasms	GPX2 GRIK2 TERT HERC3	4.40e-03	142	137	4	C0023903
Disease	Manic Disorder	SP4 ANK3 GRIK2	4.44e-03	71	137	3	C0024713

Protein segments in the cluster

Peptide	Gene	Start	Entry
CQASGQIFITQTLGI	CEACAM18	26	A8MTB9
GTNPVLNNLLSCVQE	ABL2	1161	P42684
NNVVLPLNEQTEGCL	ADGRB3	216	O60242
NQADPCVQILIQETG	EFL1	641	Q7Z2Z2
TQRNCNLTQIGGLID	GRIK1	761	P39086
RQGLQISIQSLGPCQ	AGRN	956	O00468
EILGCLVPINNITNQ	ABCA13	2676	Q86UQ4
QSGPCNKSAQVLVQE	BRWD3	21	Q6RI45
PNVVNITSARQLTGC	BRWD3	141	Q6RI45
TPNGTININEVICLA	ARAP2	941	Q8WZ64
EQISGTVSCQKQPAL	ANKRD36	1151	A6QL64
CCPQLQVLEVSTGIN	FBXL6	296	Q8N531
QQQQSCQHLGLLTPV	ANKRD17	901	O75179
KELVETVQCQGSQQP	ADAMTS13	716	Q76LX8
AQLPCQVGNTQTKAV	C9orf152	176	Q5JTZ5
PLSGSQCSVNGVQIV	KIF16B	516	Q96L93
CNQVTSSQSVRGLLP	R3HDM2	386	Q9Y2K5
TTNQGIAPVQVCTNL	RCBTB1	111	Q8NDN9
IACQNPGKQNQTTSA	RANBP2	1686	P49792
IVQIIGFSNSICNPI	QRFPR	316	Q96P65
QGQIITCPAVCNFQT	NOL11	61	Q9H8H0
VVNPGENVTVQCLLT	MDGA1	251	Q8NFP4
QCQVGVGQARPLLQV	PTPRN	61	Q16849
SCNEIQTIPSQIGNL	LRCH3	181	Q96II8
STNNPLLNNLGNVCI	IFT122	1061	Q9HBG6
INKQCPGVQLQTTTD	KIAA0825	56	Q8IV33
ETIIGNNIQLTCQSK	GPA33	151	Q99795
NNIQLTCQSKEGSPT	GPA33	156	Q99795
PLQIQSGVLTQGSCT	HIPK1	691	Q86Z02
TVPCQKIGTQGNVNF	SYK	256	P43405
PEIQKVNNSGISLCN	DST	4426	Q03001
QPNLNNLTAVGCSLA	GABBR1	626	Q9UBS5
IQKLNQQTILQVSCG	HERC3	131	Q15034
AKQNSVQEQPGTACL	ANLN	221	Q9NQW6
QPQNLSCIQKGEQGT	IL12RB2	126	Q99665
ALTNQQLPATCGARQ	CBFA2T2	101	O43439
QPCSEVLTLTNNVNK	PLXNA2	101	O75051
TCQQNSRTLGEIPTL	KIAA0232	766	Q92628
GNVNQQCIRSLLCTP	PDE5A	441	O76074
VNITQNQKAPLCNGS	IL13	51	P35225
ILSNGQQVLVCSQEG	NAXD	251	Q8IW45
CALVSQPTVQFILQG	PHRF1	1491	Q9P1Y6
TPQQISHIAGCLQLQ	POU5F2	236	Q8N7G0
LQQTQPLDSCGEQTI	NCKAP1L	771	P55160
SCNEITALPQQIGQL	LRCH1	196	Q9Y2L9
QDNIVGSNKNNTICP	PPP4R3B	521	Q5MIZ7
DNILPLVICSGISNQ	DDX11	656	Q96FC9
VSCTVGVQLPRNLQA	MROH1	1231	Q8NDA8
IQNNCSQLLTSGPAT	NFAT5	1451	O94916
NSGIQSLIGVLCIPN	RICTOR	306	Q6R327
LQRTCTGTININIQS	DSG1	471	Q02413
CQAVCQLQDVGLQTP	RNF144A	116	P50876
TIRCNPVGLQNASLV	PRTG	756	Q2VWP7
LGQSVTLACQVSAQP	OBSCN	7476	Q5VST9
GTNLSLIQCPRVQFQ	MTFR1	41	Q15390
QCQVLDLPTQEAGVN	ERVK-18	626	Q9QC07
NATIISCQQLLPATG	MLXIP	791	Q9HAP2
LQGVSQLQQSNSCPA	ERVK-5	646	Q9HDB9
QPLQCIDTGSQVCNL	FZR1	391	Q9UM11
GSNIQGSVICNNAVI	EIF2B3	401	Q9NR50
PGKSSIAVNNCIQQL	APBB3	136	O95704
SLNIQLTCNILTFGQ	IL6ST	96	P40189
VINGNPASKTLQVNC	KDM3A	211	Q9Y4C1
INQAVSCLTAGVLNP	BBS2	71	Q9BXC9
TNGRCSNQLPQSITK	FBN1	341	P35555
RSGKNIQVSQCQPVT	CEP126	811	Q9P2H0
TKGLPQTAVCNLNIT	ANK3	1421	Q12955
PGVLCLNLSNTTITN	FBXL13	271	Q8NEE6
SVLCGSQNIVLNGKT	DCTN5	26	Q9BTE1
TIPATQLAQCQLQTK	ELF2	461	Q15723
CNTTITGQPLLSDNQ	MAL2	131	Q969L2
QQCLPVLLDVGTNNE	ME3	221	Q16798
QLSLISGCPNIQEAV	CRYL1	71	Q9Y2S2
CENAQPGQVIQKISA	CDH7	491	Q9ULB5
SLTPQQAQAQGITLT	FAM186A	1626	A6NE01
NASLNPVLVNVTQGC	CRB1	871	P82279
QPTFTLVQKCEVNGQ	GPX2	96	P18283
TQRNCNLTQIGGLID	GRIK2	746	Q13002
VTQRNCNLTQIGGLI	GRIK3	746	Q13003
PSTCQRVNGIKVQNG	SLC19A2	221	O60779
GSQIQLICNVTGQLS	IL1R1	241	P14778
TGAQISSLPQTVCNQ	LGR5	336	O75473
PCEQNLGLVCLQSIT	OTOGL	526	Q3ZCN5
QIGLKNVSNVCVPQQ	RPGR	171	Q92834
NVSNVCVPQQVTIGK	RPGR	176	Q92834
PVSLLQQCTNILSQG	USO1	471	O60763
QQCTNILSQGSKIQT	USO1	476	O60763
QNAGLSQQLTITPVS	SP4	486	Q02446
LNSQSPGVRQQICSL	THADA	671	Q6YHU6
CPVSSGAQQQKQLRI	SPATA22	146	Q8NHS9
NDTQPILLQSCTGLV	SVIL	16	O95425
LKDCPTGRITQQQFQ	RCVRN	36	P35243
LQNVKNLNVCSLGVG	SLC26A5	251	P58743
VNQESLVQCQGPAII	NBEAL2	966	Q6ZNJ1
LAGQQVNPTKALCNI	HUS1	241	O60921
SLIQNTGVACPASQN	SPATA31A7	516	Q8IWB4
QVGPQSTILRTQCLC	PKD1L3	651	Q7Z443
LNTGKLQQQPGCTAE	POLR3A	731	O14802
SQPNLTKNTNQLIVC	SIMC1	651	Q8NDZ2
VTISLGTAPSLQNNQ	SIN3A	286	Q96ST3
CKSNIGQNTPFLINI	SHOC1	1196	Q5VXU9
SQGIPQLVSNISACQ	CCT7	16	Q99832
GELTCQTQSGKVNNI	WDR19	616	Q8NEZ3
PIINVNNNCATGSTA	SCP2	86	P22307
AAINLCQQQLPATGV	MLXIPL	726	Q9NP71
QLEVLCSQVQPCQTG	RD3L	81	P0DJH9
LTIQATACTPGGQIN	SETDB1	746	Q15047
QAQQLQSCQGRPSGV	SLFNL1	181	Q499Z3
NKLCLSISNLVQGVN	BPIFB2	171	Q8N4F0
QQIGGCSVTVPANVQ	AIMP2	286	Q13155
PGQNSCFLNSAVQVL	USP53	36	Q70EK8
SLIQNTGVACPASQN	SPATA31A3	516	Q5VYP0
QGQVRIISNDVCNAP	TMPRSS11D	326	O60235
VQIQKPQEGRSTACQ	SETDB2	591	Q96T68
VIQCTSQELPAQTGL	nan	181	Q6ZSR9
GLQVPIITVNACSQS	TRPM6	1591	Q9BX84
DCKNNALVPGTIQVN	PHIP	1611	Q8WWQ0
SLIQNTGVACPASQN	SPATA31A5	516	Q5VU36
KNQIIACNGSIQSIP	RRM1	656	P23921
KGLTNNSPEIQVVCS	SPIDR	421	Q14159
INQLITMCTQQAPGQ	TLN1	1346	Q9Y490
LGSQKPVQRAAICQN	TONSL	271	Q96HA7
LQVQTGKDAPSNCVV	VSIR	166	Q9H7M9
QGQITLKENQICVSS	STAC	361	Q99469
NNSLTPSLQEQLCQL	TMEM214	331	Q6NUQ4
TGSNGLPSILQTCQI	ZHX1	376	Q9UKY1
QTCQIVGQPGLVLTQ	ZHX1	386	Q9UKY1
SCVTNLGQQLDLGTP	ROS1	36	P08922
NLVQGTQTSQLSLQP	USF3	1526	Q68DE3
SQQLQCQPSLLGVNN	TECPR2	1071	O15040
QPLCSQLAGLSQGQK	WNT5A	66	P41221
NILPGELVTLTCQVN	SIGLEC1	251	Q9BZZ2
KDPVGTQLQQACAQV	nan	166	Q6ZWC4
PCQTELSNIQKRQGV	SPOCK3	316	Q9BQ16
SCTNQLGQGKRQPVV	PMS2	201	P54278
ISGQTSCPNNVQISV	ZCCHC14	651	Q8WYQ9
ILQTALPCQILGQTS	ZHX2	361	Q9Y6X8
SNVAPLCQITVKIGN	ZBTB38	831	Q8NAP3
QKQVQIAQASGPELC	TCHHL1	821	Q5QJ38
PKQSNCVTLLDTNQV	VWA8	1411	A3KMH1
LVSIPVCNNSSVQVG	TG	1341	P01266
VQCQGIPQGSILSTL	TERT	826	O14746
SLNQQRLQGQLCDVS	ZBTB22	46	O15209
CGIVPQLQNIVSTVN	TBPL2	196	Q6SJ96
GNVLQIVESCSQLQG	TLE6	76	Q9H808
VCQPGRNTIQITVTA	ZMIZ1	656	Q9ULJ6
AQCPETNISSIQIQG	NAALADL2	561	Q58DX5
LSQPTTNLVAGCLQL	NEUROD1	176	Q13562
LSQPTTNLVAGCLQL	NEUROD2	196	Q15784
GLSQPTSNLVAGCLQ	NEUROD4	161	Q9HD90
TSNLVAGCLQLGPQS	NEUROD4	166	Q9HD90
QPTTNLVAGCLQLNA	NEUROD6	171	Q96NK8