Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP17L21 USP17L23 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

9.34e-1811412116GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP17L21 USP17L23 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.74e-1712412116GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP17L21 USP17L23 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.91e-1613712116GO:0019783
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP17L21 USP17L23 USP17L12 PIGK USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

2.32e-1519212117GO:0008234
GeneOntologyMolecularFunctionpeptidase activity

USP17L21 USP17L23 USP17L12 PIGK USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 CARD8 USP17L18 USP51 USP17L17 MIPEP USP17L6P USP17L22 USP17L15 USP17L13

1.45e-0865412119GO:0008233
GeneOntologyMolecularFunctionbisphosphoglycerate mutase activity

PGAM1 PGAM2

2.17e-0441212GO:0004082
GeneOntologyMolecularFunction2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity

PGAM1 PGAM2

2.17e-0441212GO:0046538
GeneOntologyMolecularFunctionphosphoglycerate mutase activity

PGAM1 PGAM2

2.17e-0441212GO:0004619
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

NCOA3 TACC1 NR0B2

2.67e-04211213GO:0042975
GeneOntologyMolecularFunctionhistone modifying activity

NCOA3 KDM5B RPS6KA4 SIRT7 KMT2E USP51 UHRF1

4.97e-042291217GO:0140993
GeneOntologyBiologicalProcessprotein deubiquitination

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

8.24e-1612512215GO:0016579
GeneOntologyBiologicalProcessprotein modification by small protein removal

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

7.07e-1514412215GO:0070646
GeneOntologyBiologicalProcesspost-translational protein modification

USP17L21 RPS6KA4 USP17L12 HECW1 TRIM75 USP17L20 USP17L11 USP17L24 USP17L5 G2E3 USP17L10 USP17L19 SIRT7 USP17L18 LIMK1 USP51 USP17L17 USP17L6P UHRF1 USP17L22 USP17L15 USP17L13

3.04e-07107412222GO:0043687
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

USP17L21 USP17L12 HECW1 TRIM75 USP17L20 USP17L11 USP17L24 USP17L5 G2E3 USP17L10 USP17L19 SIRT7 USP17L18 LIMK1 USP51 USP17L17 USP17L6P UHRF1 USP17L22 USP17L15 USP17L13

4.53e-07100912221GO:0070647
GeneOntologyCellularComponentendoplasmic reticulum membrane

USP17L21 USP17L12 PIGK USP17L20 USP17L11 SLC43A1 DDN USP17L5 USP17L10 USP17L19 ATP10A USP17L18 PKMYT1 GRAMD2A USP17L17 USP17L6P PNPLA3 USP17L22 ATP2A1 USP17L15 USP17L13

2.03e-05129312321GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

USP17L21 USP17L12 PIGK USP17L20 USP17L11 SLC43A1 DDN USP17L5 USP17L10 USP17L19 ATP10A USP17L18 PKMYT1 GRAMD2A USP17L17 USP17L6P PNPLA3 USP17L22 ATP2A1 USP17L15 USP17L13

2.17e-05129912321GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

USP17L21 USP17L12 PIGK USP17L20 USP17L11 SLC43A1 DDN USP17L5 USP17L10 USP17L19 ATP10A USP17L18 PKMYT1 GRAMD2A USP17L17 USP17L6P PNPLA3 USP17L22 ATP2A1 USP17L15 USP17L13

2.97e-05132712321GO:0042175
DomainHABP4_PAI-RBP1

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L22 USP17L13

1.86e-211611911PF04774
DomainHABP4_PAIRBP1-bd

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L22 USP17L13

1.86e-211611911IPR006861
DomainUSP_CS

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L22 USP17L13

2.24e-166611913IPR018200
DomainUSP_1

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L22 USP17L13

5.10e-167011913PS00972
DomainUCH

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L22 USP17L13

6.20e-167111913PF00443
DomainUSP_2

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L22 USP17L13

6.20e-167111913PS00973
DomainUSP_3

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L22 USP17L13

7.53e-167211913PS50235
DomainUSP_dom

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L22 USP17L13

7.53e-167211913IPR028889
DomainPeptidase_C19_UCH

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP51 USP17L17 USP17L22 USP17L13

7.53e-167211913IPR001394
DomainPhosphogly_mut1

PGAM1 PGAM2

2.40e-0441192IPR005952
Domain-

ATP10A ATP2A1 ATP4A

1.09e-033211933.40.1110.10
Domain-

ATP10A ATP2A1 ATP4A

1.09e-033211932.70.150.10
DomainPG/BPGM_mutase_AS

PGAM1 PGAM2

1.41e-0391192IPR001345
DomainATPase_P-typ_cyto_domN

ATP10A ATP2A1 ATP4A

1.42e-03351193IPR023299
DomainATPase_P-typ_P_site

ATP10A ATP2A1 ATP4A

1.54e-03361193IPR018303
DomainP_typ_ATPase

ATP10A ATP2A1 ATP4A

1.54e-03361193IPR001757
DomainATPASE_E1_E2

ATP10A ATP2A1 ATP4A

1.54e-03361193PS00154
DomainHAD-like_dom

EYA4 ATP10A ATP2A1 ATP4A

1.63e-03791194IPR023214
DomainATPase_P-typ_transduc_dom_A

ATP10A ATP2A1 ATP4A

1.67e-03371193IPR008250
DomainE1-E2_ATPase

ATP10A ATP2A1 ATP4A

1.67e-03371193PF00122
DomainPGAM

PGAM1 PGAM2

1.75e-03101192SM00855
DomainHydrolase_3

ATP10A ATP2A1

1.75e-03101192PF08282
DomainPG_MUTASE

PGAM1 PGAM2

1.75e-03101192PS00175
DomainZnf_FYVE_PHD

KDM5B G2E3 KMT2E MTMR3 UHRF1

2.51e-031471195IPR011011
DomainPHD

KDM5B G2E3 KMT2E UHRF1

2.52e-03891194SM00249
DomainHis_Pase_superF_clade-1

PGAM1 PGAM2

2.55e-03121192IPR013078
DomainHis_Phos_1

PGAM1 PGAM2

2.55e-03121192PF00300
DomainZnf_PHD

KDM5B G2E3 KMT2E UHRF1

2.73e-03911194IPR001965
DomainZF_PHD_2

KDM5B G2E3 KMT2E UHRF1

3.19e-03951194PS50016
DomainZF_PHD_1

KDM5B G2E3 KMT2E UHRF1

3.32e-03961194PS01359
DomainWW

HECW1 APBB2 PLEKHA5

3.33e-03471193PF00397
DomainWW

HECW1 APBB2 PLEKHA5

3.54e-03481193SM00456
DomainWW_DOMAIN_1

HECW1 APBB2 PLEKHA5

4.20e-03511193PS01159
DomainWW_DOMAIN_2

HECW1 APBB2 PLEKHA5

4.20e-03511193PS50020
DomainWW_dom

HECW1 APBB2 PLEKHA5

4.44e-03521193IPR001202
DomainIRK

KCNJ8 KCNJ16

4.56e-03161192PF01007
DomainATPase_P-typ_TM_dom

ATP2A1 ATP4A

4.56e-03161192IPR023298
DomainK_chnl_inward-rec_Kir_cyto

KCNJ8 KCNJ16

4.56e-03161192IPR013518
Domain-

ATP2A1 ATP4A

4.56e-031611921.20.1110.10
Domain-

KCNJ8 KCNJ16

4.56e-031611922.60.40.1400
DomainK_chnl_inward-rec_Kir

KCNJ8 KCNJ16

4.56e-03161192IPR016449
DomainATPase_P-typ_cation-transptr_C

ATP2A1 ATP4A

5.14e-03171192IPR006068
DomainCation_ATPase_C

ATP2A1 ATP4A

5.14e-03171192PF00689
DomainCation_ATPase_N

ATP2A1 ATP4A

5.76e-03181192PF00690
DomainCation_ATPase_N

ATP2A1 ATP4A

5.76e-03181192SM00831
DomainPH_dom-like

EPS8L2 ARHGAP15 RANBP3 APBB2 EPB41L3 NBEAL2 MTMR3 PLEKHA5

5.96e-034261198IPR011993
PathwayREACTOME_RAS_PROCESSING

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.54e-18459513MM15671
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

4.55e-101919513MM15289
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L22 USP17L15 USP17L13

2.73e-092219513M27578
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

2.11e-082629513MM15286
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L22 USP17L15 USP17L13

9.97e-082999513M27574
PathwayREACTOME_MAPK_FAMILY_SIGNALING_CASCADES

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

2.03e-073189513MM15278
Pubmed

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.74e-2721125138622927
Pubmed

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.74e-27211251314583620
Pubmed

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.74e-27211251311468161
Pubmed

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.74e-2721125138756639
Pubmed

Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.74e-27211251312447969
Pubmed

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.74e-27211251318980247
Pubmed

JAK2 is required for induction of the murine DUB-1 gene.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

4.25e-2722125139154835
Pubmed

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

2.12e-2624125138995226
Pubmed

Cdc25A and Dub3 in a high-stakes balancing act.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

2.19e-26331251420228807
Pubmed

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251420403174
Pubmed

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251417109758
Pubmed

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251420388806
Pubmed

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251414699124
Pubmed

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251420715989
Pubmed

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-2634125149806828
Pubmed

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251420368735
Pubmed

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251415780755
Pubmed

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251419188362
Pubmed

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251411941478
Pubmed

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251410936051
Pubmed

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.71e-26341251421448158
Pubmed

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

4.40e-26251251321115691
Pubmed

Cytokine-regulated protein degradation by the ubiquitination system.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

6.16e-26351251416611142
Pubmed

Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

6.16e-26351251421239494
Pubmed

Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

8.78e-26261251335816173
Pubmed

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.00e-25361251420147298
Pubmed

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.61e-25371251420228808
Pubmed

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

5.68e-25291251332527007
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 PRAMEF1 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

2.38e-23501251431806660
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

USP17L21 EYA4 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 UPF3B USP17L19 PRAMEF1 USP17L18 BTN2A2 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

3.60e-106741251737196079
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L19 USP17L18 USP17L17

2.62e-07119125728625976
Pubmed

UHRF1 establishes crosstalk between somatic and germ cells in male reproduction.

TJP2 UHRF1 PLEKHA5

1.26e-0513125335440090
Pubmed

Isolation of a cDNA encoding the muscle-specific subunit of human phosphoglycerate mutase.

PGAM1 PGAM2

1.28e-05212522822696
Pubmed

Phosphoglycerate mutase isozyme marker for tissue differentiation in man.

PGAM1 PGAM2

1.28e-05212524827367
Pubmed

Upregulated UHRF1 promotes bladder cancer cell invasion by epigenetic silencing of KiSS1.

UHRF1 KISS1

1.28e-052125225272010
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

EHBP1 KDM5B RANBP3 MAP3K20 EPB41L3 CARD8 CDC42EP1 LIMK1 STARD9 TJP2 PLEKHA5 SRPK3 SRRM2

1.43e-058611251336931259
Pubmed

Characterization of genetically modified mice for phosphoglycerate mutase, a vitally-essential enzyme in glycolysis.

PGAM1 PGAM2

3.84e-053125233914812
Pubmed

Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis.

PGAM1 PGAM2

3.84e-053125232634742
Pubmed

Mouse phosphoglycerate mutase M and B isozymes: cDNA cloning, enzyme activity assay and mapping.

PGAM1 PGAM2

3.84e-053125211250083
Pubmed

Developmental activation of phosphoglycerate mutase-2 in the testis of the mouse.

PGAM1 PGAM2

3.84e-05312522824255
Pubmed

Frameshift mutations of immunomodulatory BTN2A1, BTN2A2, and BTNL3 genes in colon cancers.

CHKB BTN2A2

3.84e-053125237634314
Pubmed

Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP.

NCOA3 NR0B2

3.84e-053125215723037
Pubmed

Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.

EHBP1 ARHGAP15 CKAP2L

7.62e-0523125320468071
Pubmed

Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner.

NCOA3 NR0B2

7.65e-054125211668176
Pubmed

Embryonic demise caused by targeted disruption of a cysteine protease Dub-2.

USP17L15 USP17L13

7.65e-054125222984479
Pubmed

Deacetylation of phosphoglycerate mutase in its distinct central region by SIRT2 down-regulates its enzymatic activity.

PGAM1 PGAM2

7.65e-054125225195573
Pubmed

A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese.

MIPEP MTMR3

7.65e-054125221725308
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NCOA3 EYA4 MAP3K20 TRMT1 EPB41L3 TJP2 UHRF1 PLEKHA5 SRRM2

8.95e-05503125916964243
Pubmed

Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos.

IGDCC3 XDH PCDH8

9.84e-0525125315857914
Pubmed

The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9.

RFC3 RAD17

1.27e-045125210884395
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP10A ATP2A1 ATP4A

1.55e-0429125315071553
Pubmed

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

RPS6KA4 MAP3K20 PKMYT1 LIMK1

1.85e-0478125417192257
Pubmed

Replication protein A-mediated recruitment and activation of Rad17 complexes.

RFC3 RAD17

1.90e-046125214605214
Pubmed

Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation.

SIRT7 NR0B2

1.90e-046125220375098
Pubmed

Purification and characterization of human DNA damage checkpoint Rad complexes.

RFC3 RAD17

1.90e-046125211572977
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

INTU POLRMT SIPA1 RFC3 EPB41L3 CDC42EP1 PWWP2B TNFSF13B CIZ1 MLLT1 SLFN11 TAF5 SRRM2

1.98e-0411161251331753913
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NCOA3 RPS6KA4 KMT2E NBPF19 STARD9 SRRM2

2.05e-04233125637704626
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOA3 EYA4 LRRC42 CIZ1 CKAP2L

2.30e-04152125538360978
Pubmed

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

ATP2A1 EBF4

2.66e-047125224786561
Pubmed

Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

UPF3B CDC42EP1 PLEKHA5 SLFN11

3.07e-0489125423891004
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

RPS6KA4 HECW1 USP17L10 KMT2E PGAM1 GRK1 GALNT11 MTMR3 TAF5 ATP4A

3.17e-047301251034857952
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

EPS8L2 PGAM2 CKAP2L MLLT1 PLEKHA5 TACC1 IK SRRM2

3.19e-04472125838943005
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

MAP3K20 UPF3B ATP10A TJP2 PLEKHA5 SRRM2 ATP4A

3.43e-04361125726167880
Pubmed

Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy.

RFC3 RAD17

3.54e-048125211907025
Pubmed

Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm2.

PGAM1 PGAM2

3.54e-048125224567357
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

EHBP1 NCOA3 EPS8L2 MAP3K20 UPF3B GMIP BLZF1 CDC42EP1 UTP15 TJP2 PLEKHA5 IK

3.76e-0410381251226673895
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

POLRMT EPB41L3 NSUN7 NBEAL2 TJP2 PLEKHA5 IK ANO3

4.50e-04497125836774506
Pubmed

High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.

USP17L6P USP17L15

5.66e-0410125224207026
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

UPF3B LIMK1 TAF5 SRRM2 HTT

5.79e-04186125533637726
Pubmed

The DNA sequence and biology of human chromosome 19.

RANBP3 POLRMT ETV2 TRMT1 UHRF1 ATP4A

5.86e-04284125615057824
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

RPS6KA4 CIZ1 PLEKHA5 SRRM2

6.39e-04108125419531213
Pubmed

DNA damage-induced ubiquitylation of RFC2 subunit of replication factor C complex.

RFC3 RAD17

6.90e-0411125218245774
Pubmed

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.

NCOA3 NR0B2

6.90e-0411125236613751
Pubmed

Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.

USP17L6P USP17L15

8.26e-0412125224695638
Pubmed

ES cell neural differentiation reveals a substantial number of novel ESTs.

USP17L6P USP17L15

1.13e-0314125211793228
Pubmed

New nomenclature for chromatin-modifying enzymes.

NCOA3 KDM5B KMT2E

1.15e-0357125318022353
Pubmed

International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels.

KCNJ8 KCNJ16

1.30e-0315125216382105
Pubmed

A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.

ASTN2 PCDH8

1.30e-0315125222658931
Pubmed

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.

EHBP1 RANBP3 LRRC42 TJP2 TACC1

1.38e-03226125531452512
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

EHBP1 TJP2 SRRM2 KISS1

1.39e-03133125415144186
Pubmed

Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.

UPF3B UTP15 TJP2 UHRF1

1.42e-03134125428695742
Pubmed

Whole-transcriptome splicing profiling of E7.5 mouse primary germ layers reveals frequent alternative promoter usage during mouse early embryogenesis.

TJP2 UHRF1

1.49e-0316125229592913
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

TCEA1 NCOA3 KDM5B TRIM75 UPF3B RFC3 UHRF1

1.58e-03469125727634302
Pubmed

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

USP17L6P USP17L15

2.11e-0319125228067227
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF1 UHRF1

2.11e-0319125228604677
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

TCEA1 HECW1 KPNA7 SLFN11 SRRM2

2.15e-03250125533536335
Pubmed

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.

DGKG ATP2A1

2.33e-0320125219079260
Pubmed

Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.

FAM234A F8

2.33e-0320125223446634
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

MAP3K20 EPB41L3 TJP2 PLEKHA5 SRRM2

2.34e-03255125515324660
Pubmed

Human mediator subunit MED26 functions as a docking site for transcription elongation factors.

TCEA1 MLLT1 TAF5

2.35e-0373125321729782
Pubmed

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.

KDM5B BLZF1 KISS1

2.44e-0374125319536175
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

POLRMT SIRT7 EPB41L3 PGAM1 UTP15 TJP2 IK SRRM2

2.55e-03653125822586326
Pubmed

Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.

ETV2 ATP2A1

2.57e-0321125228302382
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA3 NR0B2

2.57e-0321125219596656
Pubmed

Oxidized thioredoxin-1 restrains the NLRP1 inflammasome.

ATP10A CARD8

2.57e-0321125236332009
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM5B KMT2E

2.57e-0321125227626377
Pubmed

Rare independent mutations in renal salt handling genes contribute to blood pressure variation.

KCNJ8 KCNJ16

2.82e-0322125218391953
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

ROR1 IGDCC3 IGSF10 CNTN3

2.84e-03162125425826454
Pubmed

An investigation into the human serum "interactome".

NCOA3 RANBP3 DGKG CHKB

2.84e-03162125415174051
Pubmed

Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.

ARX PLEKHA5

3.09e-0323125228036337
Cytoband4p16.1

USP17L21 USP17L23 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P ZNF518B USP17L22 USP17L15 USP17L13

6.29e-2679125164p16.1
CytobandEnsembl 112 genes in cytogenetic band chr4p16

USP17L21 USP17L23 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P ZNF518B USP17L22 USP17L15 HTT USP17L13

5.85e-2022212517chr4p16
GeneFamilyBisphosphoglycerate phosphatases

PGAM1 PGAM2

1.15e-0448021082
GeneFamilyPHD finger proteins

KDM5B G2E3 KMT2E UHRF1

6.80e-049080488
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ROR1 IGDCC3 IGSF10 CNTN3 IGSF9B

7.39e-04161805593
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ8 KCNJ16

2.23e-0316802276
CoexpressionMADAN_DPPA4_TARGETS

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.63e-168612213MM1312
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

5.76e-1511212213MM1095
CoexpressionGERY_CEBP_TARGETS

USP17L21 USP17L12 USP17L20 USP17L11 USP17L5 XDH USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

2.71e-1416012214MM1155
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP

USP17L21 USP17L12 USP17L20 USP17L11 POLRMT USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 NBEAL2 USP17L6P USP17L22 USP17L15 USP17L13

3.52e-0764712215MM981
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

USP17L21 KDM5B USP17L12 GBP7 USP17L20 USP17L11 POLRMT USP17L5 USP17L10 UPF3B USP17L19 SIRT7 USP17L18 USP17L17 NBEAL2 USP17L6P IK USP17L22 USP17L15 USP17L13

9.62e-07122612220MM979
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

NCOA3 USP17L21 KDM5B SPATA6 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 SRRM2 USP17L15 USP17L13

9.93e-06107212217MM1031
CoexpressionBRUINS_UVC_RESPONSE_LATE

USP17L21 EPS8L2 USP17L12 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 RFC3 USP17L18 USP17L17 MIPEP USP17L6P TJP2 USP17L22 USP17L15 USP17L13

4.08e-05119812217MM1062
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 ESPNL MAP3K20 DGKG ATP10A SLCO5A1 SRPK3 IGSF9B

1.98e-081751168d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 ESPNL MAP3K20 DGKG ATP10A SLCO5A1 SRPK3 IGSF9B

1.98e-081751168454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG PGAM2 ATP10A SRPK3 ANO3

6.54e-071891167032f169e8ede653117919bf97c17f92043320b3c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG PGAM2 ATP10A SRPK3 ANO3

6.54e-07189116707208d32afca6f93207a2ac35b647b31a9f71b7c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG ATP10A SLCO5A1 IGSF9B ANO3

6.54e-071891167127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG ATP10A SLCO5A1 IGSF9B ANO3

6.54e-0718911672cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG ATP10A SRPK3 IGSF9B ANO3

7.27e-071921167bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG ATP10A SRPK3 IGSF9B ANO3

7.27e-071921167b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8L2 HECW1 EPB41L3 PLEKHA5 PNPLA3 SRRM2

8.54e-061831166facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPS8L2 ROR1 APBB2 EPB41L3 GRAMD2A NBEAL2

9.09e-0618511661c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 APBB2 DGKG ATP10A STARD9 ANO3

9.66e-06187116615d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 APBB2 DGKG ATP10A STARD9 ANO3

9.66e-061871166f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 APBB2 DGKG ATP10A STARD9 ANO3

9.96e-06188116632f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellCOPD-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

TSPAN12 EPS8L2 ROR1 EPB41L3 NBEAL2 TACC1

1.03e-05189116614e8e57e4db336fbef005270647983b4edf407c0
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPS8L2 EYA4 ROR1 APBB2 EPB41L3 NBEAL2

1.06e-05190116630b50d183d7649146eb1e79b47ba897355f1998a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DGKG ATP10A STARD9 TACC1 IGSF9B ANO3

1.09e-05191116604c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellfacs-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 NCOA3 GBP7 APBB2 F8 CDC42EP1

1.19e-0519411665fa2dfca32cca4abfda0af90b83f2b2a826f9b6e
ToppCellfacs-Kidney-nan-3m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 NCOA3 GBP7 APBB2 F8 CDC42EP1

1.19e-05194116604df35246287815bdd28adaf885bdb98cf49524e
ToppCellfacs-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 NCOA3 GBP7 APBB2 F8 CDC42EP1

1.19e-05194116690928d6c96c6304ae35dcc0275f7889de93da100
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

EYA4 ROR1 MAP3K20 DGKG SLCO5A1 PLEKHA5

1.23e-05195116675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellAT1_cells|World / lung cells shred on cell class, cell subclass, sample id

EPS8L2 EYA4 ROR1 APBB2 CHKB NBEAL2

1.23e-051951166792d6a49b0a875a00569071183d195287a9925c5
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

EPS8L2 EYA4 ROR1 APBB2 EPB41L3 NBEAL2

1.26e-0519611666c99d29162848161c1f166a032320f87a5d5a631
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

EPS8L2 EYA4 ROR1 APBB2 EPB41L3 NBEAL2

1.30e-05197116669d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

EPS8L2 EYA4 ROR1 APBB2 EPB41L3 NBEAL2

1.30e-051971166e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-OPC_related-OPC|GW12 / Sample Type, Dataset, Time_group, and Cell type.

TSPAN12 DGKG PKMYT1 CNTN3 ANO3 ATP4A

1.38e-051991166c0dc14fb9899d4263264347436de121814441dfb
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC34A3 RFC3 EPB41L3 PKMYT1 CKAP2L UHRF1

1.38e-0519911661d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-OPC_related|GW12 / Sample Type, Dataset, Time_group, and Cell type.

TSPAN12 DGKG PKMYT1 CNTN3 ANO3 ATP4A

1.38e-0519911669bc53ff93ca97af4ee0f01c74a567987a26abb18
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Crh_(Neuron.Gad1Gad2.Sst-Crh)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PRICKLE4 TRIM75 BTN2A2 TNFSF13B

2.52e-05651164d77193259479d0c1667804682dc5b605ebf7119b
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Crh_(Neuron.Gad1Gad2.Sst-Crh)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PRICKLE4 TRIM75 BTN2A2 TNFSF13B

2.52e-05651164443827bb2c469046026ca9b4c52b22bef0681dff
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 GBP7 PKMYT1 UHRF1 EBF4

4.30e-05148116518cfecd6ae20edb74f5d44ba759909df356acf3a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP15 ATP10A CKAP2L UHRF1 ITPRIPL1

6.23e-051601165fe9970c160159b35f6599ed13c89cfb49264d554
ToppCell5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARX PGAM2 FAM135B SRPK3 NR0B2

6.61e-051621165478cf560ef33c5c324142c76417447d4a571a2c9
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYA4 ROR1 MAP3K20 DGKG SLCO5A1

8.30e-0517011653f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP15 IGDCC3 ATP10A KCNJ8 ANO3

8.30e-05170116587cac555f16b6c2ef3d1b3a00f992d8bf2237b50
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

SAXO1 RFC3 PKMYT1 CKAP2L UHRF1

8.30e-0517011655319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 APBB2 DGKG CNTN3 ANO3

8.30e-051701165876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 APBB2 DGKG CNTN3 ANO3

8.30e-0517011651f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 DGKG STARD9 CNTN3 ANO3

8.77e-05172116508a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 DGKG STARD9 CNTN3 ANO3

8.77e-051721165553701349444eb366df3c11f54bb093434f153c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP15 PKMYT1 CKAP2L UHRF1 ITPRIPL1

9.26e-0517411657b318796728001c17b4043d2b033330c7be40c78
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

EPS8L2 EYA4 ROR1 APBB2 EPB41L3

9.26e-051741165548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PKMYT1 IGSF10 TJP2 CKAP2L UHRF1

9.51e-051751165cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell10x_5'_v1-Neoplastic-Stem-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PKMYT1 IGSF10 TJP2 CKAP2L UHRF1

9.51e-051751165a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PKMYT1 GRAMD2A CKAP2L UHRF1 NR0B2

9.51e-051751165fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PKMYT1 IGSF10 TJP2 CKAP2L UHRF1

9.51e-0517511658a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PKMYT1 IGSF10 TJP2 CKAP2L UHRF1

9.51e-051751165378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

PKMYT1 GRAMD2A CKAP2L UHRF1 NR0B2

9.51e-05175116536c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SAXO1 RFC3 PKMYT1 CKAP2L UHRF1

9.77e-0517611658813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RPS6KA4 ARHGAP15 ATP10A TNFSF13B SRPK3

9.77e-051761165f3bbe8c1a8d132705eac360cf531261271d84588
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8L2 ROR1 EPB41L3 GRAMD2A NBEAL2

1.00e-0417711659af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellASK454-Epithelial-Ciliated|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SPATA6 USP51 STARD9 KCNJ16 ANO3

1.06e-041791165f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

EPS8L2 EYA4 ROR1 APBB2 GRAMD2A

1.06e-0417911651603117b52623663458a977c94bf7f9f6c1114b8
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SAXO1 RFC3 PKMYT1 CKAP2L UHRF1

1.06e-041791165e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8L2 ABCA4 ROR1 EPB41L3 GRAMD2A

1.06e-04179116504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYA4 ROR1 MAP3K20 DGKG SLCO5A1

1.11e-041811165719eb532453ab7cd7893726885bc75d74a10b21e
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGAM2 CNTN3 PCDH8 NR0B2 ATP4A

1.14e-041821165ccfee33de0faebbe69099d4ff3c3971f6a708b99
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

EPS8L2 ROR1 ATP10A GRAMD2A NBEAL2

1.17e-0418311657b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPS8L2 EYA4 ROR1 APBB2 GRAMD2A

1.20e-04184116557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

EYA4 ROR1 DGKG SLCO5A1 PLEKHA5

1.20e-041841165ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPS8L2 EYA4 ROR1 APBB2 GRAMD2A

1.20e-041841165d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 APBB2 DGKG ATP10A ANO3

1.23e-04185116551dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA4 ETV2 IGSF10 KCNJ8 ASTN2

1.23e-041851165f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA4 ETV2 IGSF10 KCNJ8 ASTN2

1.23e-04185116540e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA4 ETV2 IGSF10 KCNJ8 ASTN2

1.23e-0418511655f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 APBB2 DGKG ATP10A ANO3

1.23e-041851165a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 DGKG ATP10A STARD9 ANO3

1.30e-04187116548bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPS8L2 ROR1 APBB2 GRAMD2A NBEAL2

1.30e-041871165d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

EPS8L2 ROR1 APBB2 EPB41L3 NBEAL2

1.30e-0418711653a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 DGKG ATP10A STARD9 ANO3

1.30e-041871165958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ROR1 SLCO5A1 NLRC5 PLEKHA5 EBF4

1.33e-04188116547bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

TSPAN12 EPS8L2 ROR1 GRAMD2A KCNJ8

1.33e-041881165be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG ATP10A ANO3

1.36e-0418911657fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG ATP10A ANO3

1.36e-04189116506b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 DGKG ATP10A STARD9 ANO3

1.36e-041891165fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

EPS8L2 EYA4 ROR1 APBB2 NBEAL2

1.36e-0418911655a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARX PGAM2 FAM135B KCNJ16 NR0B2

1.40e-0419011652375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EHBP1 HECW1 EPB41L3 FAM135B PLEKHA5

1.43e-0419111653c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

EPS8L2 ROR1 APBB2 EPB41L3 NBEAL2

1.43e-0419111653457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellDividing_Macrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

RFC3 PKMYT1 TNFSF13B CKAP2L UHRF1

1.43e-0419111653e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EHBP1 HECW1 EPB41L3 FAM135B PLEKHA5

1.43e-0419111651c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DGKG ATP10A KCNJ8 ANO3

1.43e-0419111657b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCell(3)_Macrophage_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

RFC3 PKMYT1 TNFSF13B CKAP2L UHRF1

1.43e-041911165b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DGKG ATP10A KCNJ8 ANO3

1.43e-041911165cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

EHBP1 KMT2E PLEKHA5 TACC1 SRRM2

1.47e-041921165916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

EYA4 ROR1 MAP3K20 DGKG SLCO5A1

1.50e-041931165dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EYA4 HECW1 RFC3 PKMYT1 UHRF1

1.50e-041931165bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

EYA4 HECW1 ROR1 APBB2 PLEKHA5

1.50e-041931165e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

EHBP1 KMT2E PLEKHA5 TACC1 SRRM2

1.50e-041931165e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

TSPAN12 ARHGAP15 DGKG KCNJ8 TACC1

1.54e-0419411653892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG ATP10A IGSF9B

1.54e-0419411655c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 MAP3K20 DGKG ATP10A IGSF9B

1.54e-041941165ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP15 APBB2 TNFSF13B KCNJ8 ATP4A

1.54e-041941165c45e9d09b5cd6973de6c3f1713b3bf36fa4bfe57
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

TSPAN12 EPS8L2 EYA4 ROR1 APBB2

1.58e-04195116507a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARX PGAM2 FAM135B KCNJ16 NR0B2

1.58e-0419511655f33ece997f074598b4201ff74f592ee07c86a06
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TSPAN12 EPS8L2 EYA4 ROR1 APBB2

1.58e-041951165b65511770ed67f7447847e2187555b362988af45
ToppCellILEUM-non-inflamed-(1)_Highly_activated_T_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PGAM1 PKMYT1 TNFSF13B CKAP2L UHRF1

1.62e-0419611656a415a2574bd84bd825a2bd6c8e3632a433ff7cf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 APBB2 DGKG ATP10A ANO3

1.62e-041961165b8759e6231e0254797d6c30930407b79440c57bb
ToppCell(3)_MNP-(3)_Macrophage_Dividing|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

RFC3 PKMYT1 TNFSF13B CKAP2L UHRF1

1.66e-041971165048bc4f8fd5d4f394e2384700640f72042336597
ToppCelldistal-1-Epithelial-Alveolar_Epithelial_Type_1|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8L2 EYA4 GRAMD2A KPNA7 NR0B2

1.66e-041971165d44b7dc7c6416ed9466889374c3ae39f43ac8bb6
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPS8L2 ROR1 APBB2 EPB41L3 NBEAL2

1.66e-0419711658d5097898dd01cedb04cb694cb480c931e08462c
DrugTrimethadione [127-48-0]; Up 200; 28uM; HL60; HT_HG-U133A

EPS8L2 SPATA6 HECW1 BLZF1 CIZ1 PNPLA3 SRRM2 ATP2A1 PCDH8

4.78e-0719810992486_UP
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

2.29e-234611714DOID:5426 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15 USP17L13

1.37e-206911714DOID:1682 (implicated_via_orthology)
Diseaseneutropenia, leukopenia, chemotherapy-induced cytotoxicity measurement

TNFSF13B NLRC5

1.56e-0521172EFO_0004233, EFO_0010978, MONDO_0001475
DiseaseNonsyndromic Deafness

EPS8L2 EYA4 ROR1 TJP2

3.09e-04811174C3711374
DiseaseGout

XDH CARD8

5.51e-0491172C0018099
DiseaseAutistic Disorder

KDM5B XDH KMT2E ATP10A CNTN3 ASTN2

6.23e-042611176C0004352
Diseasecup-to-disc ratio measurement, optic cup area measurement, optic disc area measurement

MAP3K20 EPB41L3

6.87e-04101172EFO_0006937, EFO_0006939, EFO_0006940
Diseasealcohol use disorder (implicated_via_orthology)

KDM5B EPS8L2 GRK1 CIZ1 SRRM2

1.10e-031951175DOID:1574 (implicated_via_orthology)
Diseaseliver neoplasm

IFNL4 PNPLA3

1.58e-03151172EFO_1001513
DiseaseDystonia, Limb

CIZ1 ANO3

2.04e-03171172C0751093
DiseaseDystonia, Diurnal

CIZ1 ANO3

2.04e-03171172C0393610
DiseaseHeadache

BTN2A2 TJP2 ASTN2

2.12e-03641173HP_0002315
DiseaseAgents acting on the renin-angiotensin system use measurement

ARHGAP15 SIPA1 PKMYT1 TJP2 UHRF1 ANO3

2.23e-033351176EFO_0009931
DiseaseDystonia, Paroxysmal

CIZ1 ANO3

2.29e-03181172C0393588
Diseaseglucose homeostasis measurement, acute insulin response measurement

MTNR1B ASTN2

2.29e-03181172EFO_0006831, EFO_0006896
Diseasenon-alcoholic fatty liver disease (is_implicated_in)

IFNL4 PNPLA3

2.29e-03181172DOID:0080208 (is_implicated_in)
Diseasecerebellum white matter volume change measurement, age at assessment

EPB41L3 TJP2

2.83e-03201172EFO_0008007, EFO_0021498
Diseasep-tau measurement

MTMR3 PCDH8 ANO3

2.97e-03721173EFO_0004763
Diseasegait measurement

ARHGAP15 UHRF1 ANO3 HTT

3.05e-031501174EFO_0007680
Diseasegamma-glutamylglutamine measurement

MIPEP ASTN2

3.42e-03221172EFO_0021138
Diseaseinterleukin 18 measurement

SLC43A1 XDH RAD17

3.46e-03761173EFO_0004581
DiseaseMalignant neoplasm of breast

EHBP1 NCOA3 ABCA4 ROR1 DGKG XDH EPB41L3 MTMR3 NLRC5 ASTN2 PCDH8

3.66e-03107411711C0006142

Protein segments in the cluster

PeptideGeneStartEntry
GNSCPELVPSRRSKL

TACC1

216

O75410
KSHLSPLERSRCSPS

C2orf16

1851

Q68DN1
CSPSERSRRSPLKEG

C2orf16

1926

Q68DN1
KSAPPQSRLSRCRAA

FAM234A

36

Q9H0X4
CSISSPLLPERRKVA

BTNL10

221

A8MVZ5
SSCEILPSQPRRTKS

APBB2

146

Q92870
PSCRCSTREKLTMLP

ABCA4

1486

P78363
SKCPDTTPKRRRASS

CHKB

26

Q9Y259
FPSPCQKRLSSSRLL

DDN

506

O94850
CLALATRDTPPKREE

ATP2A1

561

O14983
SREPDSPCRLKTVTV

ASTN2

56

O75129
TRKSPRRCSAPKETF

ATP10A

1311

O60312
KETSLKPSRRSLPCL

ANO3

26

Q9BYT9
CPPVKRERTSSLTQF

RANBP3

116

Q9H6Z4
CKRASLTELDSPRLP

RAD17

406

O75943
TEKNSTAPADRLPCR

SLC34A3

296

Q8N130
GDEKPSTRPLQDTCR

ESPNL

616

Q6ZVH7
KRRNITSFCPDTPSE

KPNA7

46

A9QM74
PRCSARELDEKPSIL

KCNJ8

351

Q15842
SERTALSPPCDCRKE

IGDCC3

616

Q8IVU1
LRILDPVTCKESSPD

BLZF1

341

Q9H2G9
ASKLCEETPITSVPR

GMIP

891

Q9P107
KSRPCSLPVSELETV

HECW1

531

Q76N89
SPLRSPLKRQASVCS

KIAA1109

1301

Q2LD37
RSVPLRKSLCSPTFL

SLC43A1

291

O75387
PESRLCLKPSDLRSF

MTNR1B

236

P49286
TFCKSTSLPRDPLRR

PCDH8

986

O95206
CPAETKAEATPRSIL

PNPLA3

436

Q9NST1
RLKPETPRSETCISN

FAM214A

446

Q32MH5
KSFSSRSPRPCLNIE

FAM214A

841

Q32MH5
CLDMSETRSSDPPRL

GALNT11

536

Q8NCW6
LPCTERKPAATARLS

KISS1

51

Q15726
SCSLPDLTTPLKKRR

KMT2E

861

Q8IZD2
ATPPRIKSDDETCRN

KMT2E

911

Q8IZD2
TELTELIRAKSCPRP

GBP7

146

Q8N8V2
VEDGPTKSDPRCLTR

F8

536

P00451
DRSSPVRPSSEKNDC

KDM5B

1381

Q9UGL1
TQAEVSRRILKCSPP

RPS6KA4

246

O75676
RSRAEAPLKCPLADT

LRRC42

341

Q9Y546
HKTPLERTESSCSRP

GLIS2

461

Q9BZE0
SSSLKAVPRPRSRCL

NR0B2

26

Q15466
PSTPRSKRLLSDDRS

PIGK

141

Q92643
PDIARSVSCPLLSRD

EPS8L2

361

Q9H6S3
LLETLPSCPRVREAS

NLRC5

1291

Q86WI3
RIDERLASSPVPCLS

INTU

641

Q9ULD6
CRLETIRDPKDTPFS

PRICKLE4

286

Q2TBC4
LSLPPSTTSCKLRLD

ITPRIPL1

341

Q6GPH6
ARSRNRLCPPDDSTK

UPF3B

446

Q9BZI7
TSICPITRDRPGEKS

DGKG

396

P49619
ITDCLLEESSPKLPR

G2E3

311

Q7L622
SPSTPIKDLDERTCR

EYA4

331

O95677
PCLTRTSKRPEESVQ

HTT

211

P42858
STVELKCRAEGRPSP

IGSF10

1761

Q6WRI0
RRLDPSEAATPCIKA

EBF4

246

Q9BQW3
VATSTLPKVRPIERC

GPR37L1

231

O60883
CTISRLPRSEKPHDR

CDC42EP1

161

Q00587
CPEKSSSSEEELPRR

CARD8

6

Q9Y2G2
RSLECRSDPESPIKK

EHBP1

741

Q8NDI1
ACLELARPGSSRKVP

IFNL4

121

K9M1U5
KNERLTIPSSCPRSF

MAP3K20

221

Q9NYL2
SERPECKSKSPTLLS

ARX

11

Q96QS3
SGRRSPESCSKPEKI

MLLT1

471

Q03111
CDPLSSTLREPLDIR

FAM135B

641

Q49AJ0
SPQSDRASLARCPKT

ETV2

221

O00321
LPPLSKCESLRDSLS

GRK1

41

Q15835
KVCPSSRSLSLPDNI

GRAMD2A

211

Q8IUY3
SSPERILPLKESLCR

BTN2A2

431

Q8WVV5
SCAPSASIPKLKLTR

PWWP2B

306

Q6NUJ5
CSLDKPHRSSRLVPV

POLRMT

591

O00411
PRATVPDAVLKCRTA

ATP4A

606

P20648
LVSLDCKPRASPRAL

CNTN3

426

Q9P232
APTSPTELRRRCKEN

EPB41L3

521

Q9Y2J2
PSCESLKDTIARALP

PGAM1

151

P18669
PLASRRCSDPSLNEK

MTMR3

626

Q13615
NSTSKVIPPIRSRCL

RFC3

166

P40938
ETTKRVRLGPDCLPS

TAF5

446

Q15542
ALDRVLDPTCTIKTP

UTP15

376

Q8TED0
CPVKRERLSETSPAF

TRMT1

506

Q9NXH9
RSRSPSSPELNNKCL

SRRM2

1496

Q9UQ35
LDLPTEPLDCLTTTR

SAXO1

361

Q8IYX7
DPSCPRLSRELLAEK

NBPF19

3101

A0A087WUL8
PTCESLKDTIARALP

PGAM2

151

P15259
VPTCLPTHSLSRKEE

NSUN7

686

Q8NE18
ASATLVRPPDCIKRS

NBEAL2

1481

Q6ZNJ1
LASDSRKRKLPCDTP

NCOA3

11

Q9Y6Q9
NAIDRLPKDSSCPSR

ARHGAP15

186

Q53QZ3
ERCEPETLRSKSLPV

SLCO5A1

26

Q9H2Y9
SCLRLGSASPKVPRT

SIPA1

306

Q96FS4
PEDRSVKPRLCSLSS

SLFN11

116

Q7Z7L1
RKPPREESSATCVLE

MUTYH

361

Q9UIF7
PETTSKRQTAEDCPR

PRAMEF1

126

O95521
PRAPSTSDSVRLKCR

TCEA1

131

P23193
SRKSLCRSREEAPPG

SIRT7

356

Q9NRC8
SPSRGKESRTLPCRQ

STARD9

2941

Q9P2P6
LLKCVRDSDPSDPKR

SRPK3

126

Q9UPE1
CLSPKEREQVTATPR

CKAP2L

636

Q8IYA6
PCEASELPAKRLRSS

CIZ1

251

Q9ULV3
DETSSVPKPRDLCRD

ROR1

236

Q01973
CPKERLTCTTELPDS

WFDC8

51

Q8IUA0
EKVLPSIPLRCHSSS

USP51

81

Q70EK9
KERPSSREDTPSRLS

TJP2

436

Q9UDY2
RKTELLVDRACSTPP

MIPEP

86

Q99797
PRSRCTPRDALDLSD

PKMYT1

456

Q99640
DPPLSITHCRKSLES

IGSF9B

761

Q9UPX0
CKDSLPTKARRPSSA

TRIM75

366

A6NK02
EIQRTSLPEKSPLSC

USP17L18

31

D6R9N7
SLPEKSPLSCETRVD

USP17L18

36

D6R9N7
SKRPCVDPELADRSA

FAM90A2P

156

Q658T7
APPVRESCTSDTKAR

KCNJ16

356

Q9NPI9
EIQRTSLPEKSPLSC

USP17L5

31

A8MUK1
SLPEKSPLSCETRVD

USP17L5

36

A8MUK1
EIQRTSLPEKSPLSC

USP17L21

31

D6R901
SLPEKSPLSCETRVD

USP17L21

36

D6R901
EIQRTSLPEKSPLSC

USP17L13

31

C9JLJ4
SLPEKSPLSCETRVD

USP17L13

36

C9JLJ4
EIQRTSLPEKSPLSC

USP17L19

31

D6RCP7
SLPEKSPLSCETRVD

USP17L19

36

D6RCP7
RLDSPATPEKIRNAC

XDH

1296

P47989
DIPTTLIRSKADCPT

IK

251

Q13123
LSCPSVELLKPSLSR

TSPAN12

271

O95859
EIQRTSLPEKSPLSC

USP17L12

31

C9JPN9
SLPEKSPLSCETRVD

USP17L12

36

C9JPN9
RKAPSRDEPCSSTSR

UHRF1

161

Q96T88
EIQRTSLPEKSPLSC

USP17L24

31

Q0WX57
SLPEKSPLSCETRVD

USP17L24

36

Q0WX57
EIQRTSLPEKSPLSC

USP17L6P

31

Q6QN14
SLPEKSPLSCETRVD

USP17L6P

36

Q6QN14
LPRNSKTRPESICSV

PLEKHA5

461

Q9HAU0
ECVSILPRKESPSVR

TNFSF13B

26

Q9Y275
EIQRTSLPEKSPLSC

USP17L22

31

D6RA61
SLPEKSPLSCETRVD

USP17L22

36

D6RA61
EQGCLDKTRRTTSPP

ZNF425

71

Q6IV72
EIQRTSLPEKSPLSC

USP17L15

31

C9J2P7
SLPEKSPLSCETRVD

USP17L15

36

C9J2P7
EIQRTSLPEKSPLSC

USP17L17

31

D6RBQ6
SLPEKSPLSCETRVD

USP17L17

36

D6RBQ6
PRSCSKPRHSARTLL

SPATA6

326

Q9NWH7
EIQRTSLPEKSPLSC

USP17L23

31

D6RBM5
SLPEKSPLSCETRVD

USP17L23

36

D6RBM5
EIQRTSLPEKSPLSC

USP17L20

31

D6RJB6
SLPEKSPLSCETRVD

USP17L20

36

D6RJB6
KLPRVSLSRPSSSCL

nan

181

Q6ZQT7
EIQRTSLPEKSPLSC

USP17L10

31

C9JJH3
SLPEKSPLSCETRVD

USP17L10

36

C9JJH3
EIQRTSLPEKSPLSC

USP17L11

31

C9JVI0
SLPEKSPLSCETRVD

USP17L11

36

C9JVI0
TPLRPKLRKESAVCS

ZNF518B

841

Q9C0D4
KPVLRSCSIDRSPGA

LIMK1

291

P53667