Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmodification-dependent protein binding

OPTN ANK2 CHD5 WDR81 HTATSF1 TAB2

6.08e-05206666GO:0140030
GeneOntologyMolecularFunctionK63-linked polyubiquitin modification-dependent protein binding

OPTN WDR81 TAB2

8.49e-0526663GO:0070530
GeneOntologyMolecularFunctionsnoRNA binding

NOLC1 NOP14 BMS1

1.92e-0434663GO:0030515
GeneOntologyBiologicalProcessrRNA metabolic process

NOLC1 NOP14 BMS1 DDX54 PDCD11 LAS1L POLR1G DDX27

2.09e-06275648GO:0016072
GeneOntologyBiologicalProcessrRNA processing

NOLC1 NOP14 BMS1 DDX54 PDCD11 LAS1L DDX27

7.08e-06230647GO:0006364
GeneOntologyBiologicalProcessregulation of SA node cell action potential

ANK2 RYR2

2.84e-053642GO:0098907
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell action potential

ANK2 RYR2

5.66e-054642GO:0098910
GeneOntologyBiologicalProcessribosome biogenesis

NOLC1 NOP14 BMS1 DDX54 PDCD11 LAS1L DDX27

8.01e-05336647GO:0042254
GeneOntologyBiologicalProcessregulation of AV node cell action potential

ANK2 RYR2

9.42e-055642GO:0098904
GeneOntologyBiologicalProcessribonucleoprotein complex biogenesis

NOLC1 NOP14 BMS1 DDX54 HTATSF1 PDCD11 LAS1L DDX27

1.86e-04515648GO:0022613
GeneOntologyCellularComponentaxoneme

CFAP251 EFHC1 TTLL3 RSPH4A ODAD2 DYNC1I2

4.86e-05207666GO:0005930
GeneOntologyCellularComponentciliary plasm

CFAP251 EFHC1 TTLL3 RSPH4A ODAD2 DYNC1I2

4.99e-05208666GO:0097014
GeneOntologyCellularComponentpreribosome

NOP14 BMS1 PDCD11 LAS1L

4.66e-04114664GO:0030684
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

CFAP251 EFHC1 TTLL3 RSPH4A ODAD2 DYNC1I2

4.91e-04317666GO:0032838
GeneOntologyCellularComponentcytoplasmic region

CFAP251 EFHC1 TTLL3 RSPH4A ODAD2 DYNC1I2

9.53e-04360666GO:0099568
GeneOntologyCellularComponentradial spoke

CFAP251 RSPH4A

1.00e-0315662GO:0001534
DomainZF_PHD_2

TRIM33 KMT2C CHD5 ASXL2

3.16e-0495644PS50016
DomainZF_PHD_1

TRIM33 KMT2C CHD5 ASXL2

3.29e-0496644PS01359
DomainHelicase_C

CHD5 DDX54 BTAF1 DDX27

4.97e-04107644PF00271
DomainHELICc

CHD5 DDX54 BTAF1 DDX27

4.97e-04107644SM00490
DomainHelicase_C

CHD5 DDX54 BTAF1 DDX27

5.14e-04108644IPR001650
DomainHELICASE_CTER

CHD5 DDX54 BTAF1 DDX27

5.33e-04109644PS51194
DomainHELICASE_ATP_BIND_1

CHD5 DDX54 BTAF1 DDX27

5.33e-04109644PS51192
DomainDEXDc

CHD5 DDX54 BTAF1 DDX27

5.33e-04109644SM00487
DomainHelicase_ATP-bd

CHD5 DDX54 BTAF1 DDX27

5.51e-04110644IPR014001
DomainNAP

NAP1L2 TSPY26P

1.52e-0317642PF00956
DomainNAP_family

NAP1L2 TSPY26P

1.52e-0317642IPR002164
DomainPHD

TRIM33 KMT2C CHD5

2.17e-0375643PF00628
DomainZnf_PHD-finger

TRIM33 KMT2C CHD5

2.52e-0379643IPR019787
DomainPHD

TRIM33 KMT2C CHD5

3.53e-0389643SM00249
DomainZnf_PHD

TRIM33 KMT2C CHD5

3.76e-0391643IPR001965
DomainLisH

NOLC1 OFD1

4.13e-0328642SM00667
DomainLisH

NOLC1 OFD1

4.13e-0328642IPR006594
DomainLISH

NOLC1 OFD1

4.13e-0328642PS50896
DomainDEAD_ATP_HELICASE

DDX54 DDX27

5.04e-0331642PS00039
DomainSNF2_N

CHD5 BTAF1

5.37e-0332642IPR000330
DomainSNF2_N

CHD5 BTAF1

5.37e-0332642PF00176
DomainRNA-helicase_DEAD-box_CS

DDX54 DDX27

5.70e-0333642IPR000629
Pubmed

Human transcription factor protein interaction networks.

NOLC1 TRIM33 KMT2C NOP14 OFD1 CHD5 BMS1 DDX54 PDCD11 ASXL2 HERC1 LAS1L ANKHD1 MIDEAS PRPF40A ZHX1 KAT14 DDX27 SFN

2.00e-111429681935140242
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

NOLC1 TRIM33 NOP14 ACAT1 POLR2A BMS1 DDX54 PDCD11 LAS1L CLSPN POLR1G MIDEAS PRPF40A DDX27 TOP2A SFN

5.97e-11989681636424410
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NOLC1 SERBP1 NOP14 HYOU1 ACAT1 POLR2A BMS1 DDX54 PDCD11 LAS1L ANKHD1 PRPF40A DDX27

3.90e-10653681322586326
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

NOLC1 SERBP1 NOP14 CHD5 BMS1 DDX54 PDCD11 LAS1L PRPF40A TOP2A

9.22e-10330681033301849
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

NOLC1 SERBP1 NOP14 CHD5 BMS1 DDX54 HTATSF1 PDCD11 LAS1L PRPF40A DDX27 TOP2A

2.07e-09605681228977666
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NOLC1 SERBP1 ANK2 POLR2A ENAH FAM169A HTATSF1 BTAF1 TTC1 ANKHD1 SHTN1 PRPF40A ENSA TOP2A

2.96e-09934681433916271
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

NOLC1 SERBP1 NOP14 POLR2A BMS1 DDX54 MAP3K20 PDCD11 LAS1L ANKHD1 PRPF40A DDX27 TOP2A

4.97e-09807681322681889
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2C SERBP1 LMO7 POLR2A ENAH PDCD11 ANKHD1 SHTN1 MIDEAS PRPF40A TOP2A

9.34e-09549681138280479
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

NOLC1 MALT1 KMT2C SERBP1 HYOU1 ACAT1 POLR2A HTATSF1 ASXL2 HERC1 LAS1L PRPF40A ENSA DDX27 DYNC1I2

2.10e-081284681517353931
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NOLC1 KMT2C ZBTB17 LMO7 POLR2A DDX54 HTATSF1 PDCD11 ASXL2 LAS1L POLR1G MIDEAS PRPF40A KAT14 TOP2A

2.33e-081294681530804502
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

NOLC1 OPTN SERBP1 LMO7 CHD5 DDX54 MAP3K20 PDCD11 LAS1L POLR1G PRPF40A DDX27 TOP2A

3.36e-08949681336574265
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NOLC1 NOP14 ACAT1 POLR2A BMS1 DDX54 MAP3K20 PDCD11 LAS1L POLR1G ANKHD1 MIDEAS DDX27 TOP2A DYNC1I2

4.18e-081353681529467282
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

NOLC1 NOP14 POLR2A BMS1 DDX54 LAS1L DDX27 NBPF20

4.27e-0825968830404004
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NOLC1 HYOU1 OFD1 ACAT1 LMO7 POLR2A DDX54 PDCD11 BTAF1 LAS1L PRPF40A DDX27 TOP2A

8.12e-081024681324711643
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

NOLC1 SERBP1 NOP14 HYOU1 LMO7 CHD5 BMS1 DDX54 MAP3K20 PDCD11 LAS1L DDX27 TOP2A SFN

1.20e-071257681436526897
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NOLC1 NOP14 HYOU1 ANK2 OFD1 BMS1 DDX54 HTATSF1 PDCD11 CRYBG3 LAS1L TTC1 PRPF40A ENSA DDX27

1.42e-071487681533957083
Pubmed

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

POLR2A DDX54 LAS1L ANKHD1 PRPF40A SFN

2.10e-0712968628973437
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

TRIM33 KMT2C ACAT1 BMS1 FAM169A PDCD11 ANKHD1 MIDEAS PRPF40A

2.68e-0745768932344865
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

POLR2A BMS1 DDX54 PDCD11 LAS1L PRPF40A DDX27 TOP2A

2.85e-0733268825693804
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

NOLC1 NOP14 POLR2A DDX54 BTAF1 LAS1L MIDEAS DDX27

3.49e-0734168832971831
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

SERBP1 NOP14 ANK2 BMS1 DDX54 FAM169A PDCD11 BTAF1 PPP1R15A CLSPN TTC1 DDX27

3.63e-07971681233306668
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

SERBP1 NOP14 BMS1 DDX54 HTATSF1 PDCD11 LAS1L DDX27

4.15e-0734968825665578
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

NOLC1 NOP14 BMS1 DDX54 PDCD11 LAS1L POLR1G DDX27 TOP2A

4.25e-0748368936912080
Pubmed

Interaction network of human early embryonic transcription factors.

TRIM33 KMT2C HYOU1 ASXL2 MIDEAS ZHX1 KAT14 TOP2A

4.34e-0735168838297188
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NOLC1 SERBP1 LMO7 ENAH MAP3K20 LAS1L POLR1G TOP2A SFN

5.96e-0750368916964243
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SERBP1 NOP14 LMO7 BMS1 DDX54 PDCD11 LAS1L POLR1G PRPF40A DDX27 TOP2A

7.25e-07847681135850772
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

NOP14 HYOU1 OFD1 POLR2A ENAH BMS1 DDX54 TAB2 CRYBG3 HERC1 ENSA DDX27

8.19e-071049681227880917
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

SERBP1 BMS1 DDX54 HTATSF1 PRPF40A TOP2A

8.32e-0716368622113938
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

NOLC1 NOP14 HYOU1 ACAT1 BMS1 DDX54 FAM169A PDCD11 CRYBG3 HERC1 LAS1L TTC1 DDX27 TOP2A

9.73e-071496681432877691
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

NOLC1 NOP14 BMS1 DDX54 PDCD11 POLR1G PRPF40A DDX27 TOP2A SFN

1.53e-06731681029298432
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NOLC1 TRIM33 MALT1 CHD5 POLR2A CRYBG3 CLSPN POLR1G ANKHD1 PRPF40A KAT14 TOP2A

1.56e-061116681231753913
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

NOLC1 SERBP1 NOP14 BMS1 DDX54 PDCD11 LAS1L POLR1G DDX27 TOP2A

2.15e-06759681035915203
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NOLC1 TRIM33 SERBP1 ACAT1 POLR2A HTATSF1 PDCD11 LAS1L MIDEAS PRPF40A TOP2A

2.30e-06954681136373674
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NOLC1 SERBP1 HYOU1 ACAT1 POLR2A ENAH BMS1 DDX54 PDCD11 ANKHD1 PRPF40A DDX27 TOP2A

3.33e-061425681330948266
Pubmed

The structure of an FF domain from human HYPA/FBP11.

POLR2A PRPF40A

3.77e-06268212381297
Pubmed

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

KMT2C SERBP1 DDX54 PDCD11 LAS1L DDX27 TOP2A

4.07e-0633368736779763
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

NOLC1 OPTN SERBP1 HYOU1 POLR2A ENAH OGFOD1 HTATSF1 HERC1 TTC1 SHTN1 DYNC1I2 SFN

4.18e-061455681322863883
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

NOLC1 TRIM33 MALT1 POLR2A ENAH MAP3K20 WDR81 TAB2 LAS1L CLSPN TTC1

5.14e-061038681126673895
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

TRIM33 KMT2C SERBP1 NOP14 POLR2A BMS1 MAP3K20 PDCD11 LAS1L POLR1G ANKHD1 ZHX1 DDX27

5.69e-061497681331527615
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SERBP1 HYOU1 OFD1 ENAH TAB2 TTC1 ENSA DDX27 TOP2A DYNC1I2

6.01e-06853681028718761
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

NOLC1 SERBP1 LMO7 ENAH HTATSF1 SHTN1 PRPF40A KAT14

6.53e-0650668830890647
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

OPTN SERBP1 LMO7 BTAF1 ANKHD1 DYNC1I2 SFN

6.77e-0636068733111431
Pubmed

The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules.

NOLC1 LMO7 DDX27 TOP2A

8.27e-066568432521226
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

NOLC1 NOP14 HYOU1 ACAT1 BMS1 DDX54 PDCD11 LAS1L POLR1G PRPF40A DDX27 TOP2A

8.53e-061318681230463901
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NOLC1 TRIM33 KMT2C LMO7 CHD5 BMS1 PDCD11 ANKHD1

9.02e-0652968814621295
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

KMT2C SERBP1 HYOU1 ACAT1 LMO7 DDX54 PDCD11 ANKHD1 DDX27

9.97e-0671168933022573
Pubmed

Postmortem genetic analysis of sudden unexplained death syndrome under 50 years of age: A next-generation sequencing study.

ANK2 RYR2

1.13e-05368227005929
Pubmed

Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons.

PIEZO2 POLR2A

1.13e-05368238743566
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

NOLC1 OPTN HYOU1 BMS1 HTATSF1 PDCD11 TTC1 PRPF40A ENSA TOP2A DYNC1I2 SFN

1.23e-051367681232687490
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

SERBP1 HYOU1 LMO7 ENAH TAB2 TTC1 ANKHD1 SHTN1 PRPF40A ENSA DYNC1I2

1.33e-051149681135446349
Pubmed

Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus.

BMS1 DDX54 PDCD11 POLR1G DDX27

1.55e-0515968534578187
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NOLC1 LMO7 POLR2A BTAF1 POLR1G PRPF40A ZHX1 TOP2A DYNC1I2

1.95e-0577468915302935
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

NOLC1 OPTN SERBP1 HYOU1 LMO7 BMS1 DDX54 PDCD11 BTAF1 LAS1L DDX27 TOP2A

2.06e-051440681230833792
Pubmed

Piezo2 regulates colonic mechanical sensitivity in a sex specific manner in mice.

PIEZO2 POLR2A

2.25e-05468237061508
Pubmed

ENSA and ARPP19 differentially control cell cycle progression and development.

POLR2A ENSA

2.25e-05468230626720
Pubmed

A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release.

PIEZO2 POLR2A

2.25e-05468230037999
Pubmed

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WDR81 LAS1L ANKHD1 ABCC10

2.40e-058568415449545
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

NOP14 CHD5 DDX54 FAM169A BTAF1 MIDEAS ZHX1 TOP2A

2.45e-0560868836089195
Pubmed

A protein interaction landscape of breast cancer.

HYOU1 POLR2A DDX54 PDCD11 LAS1L POLR1G DDX27 TOP2A

3.30e-0563468834591612
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

NOP14 ACAT1 BMS1 DDX54 PDCD11 ANKHD1 DDX27 TOP2A

3.56e-0564168836057605
Pubmed

A requirement for filopodia extension toward Slit during Robo-mediated axon repulsion.

GAP43 ENAH

3.75e-05568227091449
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

NOLC1 SERBP1 LMO7 POLR2A PRPF40A DDX27 TOP2A SFN

4.02e-0565268831180492
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

NOLC1 SERBP1 DDX54 LAS1L ANKHD1 MIDEAS PRPF40A DDX27

4.15e-0565568835819319
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NOLC1 OPTN OFD1 LMO7 MAP3K20 TAB2 CRYBG3 SHTN1 SFN

4.47e-0586168936931259
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

HYOU1 ACAT1 PDCD11 TAB2 LAS1L DDX27 TOP2A

4.51e-0548468731995728
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

SERBP1 NOP14 POLR2A OGFOD1 PDCD11 LAS1L PRPF40A DYNC1I2

4.86e-0567068822990118
Pubmed

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

POLR2A DDX54 PDCD11 TOP2A

5.30e-0510468426167872
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

TRIM33 POLR2A BMS1 PDCD11 LAS1L CLSPN

5.40e-0533968630415952
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

BMS1 DDX54 PDCD11 LAS1L PRPF40A TOP2A

5.49e-0534068629478914
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SERBP1 ANK2 LMO7 BMS1 MAP3K20 PDCD11 LAS1L ANKHD1 MIDEAS PRPF40A DDX27

6.68e-051371681136244648
Pubmed

The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.

NOLC1 HTATSF1 LAS1L PRPF40A TOP2A

7.30e-0522068534091597
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

NOLC1 CFAP251 LMO7 MAP3K20 HTATSF1 ENSA

7.64e-0536168626167880
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

NOLC1 SERBP1 HYOU1 POLR2A ENAH DDX54 HTATSF1 ANKHD1 TOP2A DYNC1I2 SFN

8.84e-051415681128515276
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

SERBP1 DDX54 HERC1 PRPF40A TOP2A

9.75e-0523468536243803
Pubmed

Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat.

POLR2A HTATSF1 BTAF1

1.02e-04466838849451
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NOLC1 NOP14 HYOU1 ANK2 LMO7 CHD5 FAM169A TOP2A DYNC1I2 RYR2 SFN

1.05e-041442681135575683
Pubmed

Tat-SF1 protein associates with RAP30 and human SPT5 proteins.

POLR2A HTATSF1

1.05e-04868210454543
Pubmed

Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation.

MALT1 TAB2

1.05e-04868217948050
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

DDX54 MIDEAS DDX27 TOP2A SFN

1.21e-0424568521182205
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

DDX54 PDCD11 MIDEAS DDX27 TOP2A DYNC1I2

1.23e-0439468627248496
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

SERBP1 GAP43 ENAH HTATSF1 POLR1G

1.23e-0424668515345747
Pubmed

FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.

TRIM33 KMT2C LAS1L POLR1G TOP2A

1.28e-0424868527926873
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

NOLC1 KMT2C SERBP1 DDX54 TOP2A

1.35e-0425168531076518
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

NOLC1 SERBP1 DDX54 DDX27 TOP2A

1.40e-0425368529911972
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

NOLC1 LMO7 ENAH BTAF1 LAS1L PRPF40A TOP2A

1.42e-0458268720467437
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

NOLC1 LMO7 MAP3K20 PRPF40A SFN

1.46e-0425568515324660
Pubmed

Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.

NOLC1 POLR2A PRPF40A

1.48e-045268324591637
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

NOLC1 TRIM33 SERBP1 ACAT1 POLR2A HTATSF1 POLR1G PRPF40A TOP2A

1.55e-04101468932416067
Pubmed

Functional proteomics mapping of a human signaling pathway.

OPTN HTATSF1 ASXL2 PPP1R15A HERC1 PRPF40A RYR2

1.56e-0459168715231748
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

NOLC1 TRIM33 LMO7 LAS1L TOP2A

1.65e-0426268536880596
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

SERBP1 DDX54 TAB2 POLR1G DDX27 TOP2A

1.68e-0441768636537216
Pubmed

FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.

ENAH PRPF40A

1.68e-04106829171351
Pubmed

Identification of differential protein interactors of lamin A and progerin.

SERBP1 TOP2A SFN

1.74e-045568321327095
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

SERBP1 ANK2 CHD5 LAS1L TOP2A

1.93e-0427168532433965
Pubmed

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

NOLC1 CHD5 PRPF40A

1.94e-045768321555454
Pubmed

RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity.

NOP14 LAS1L DDX27 TOP2A

1.97e-0414668421589869
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

CHD5 HTATSF1 CLSPN ZHX1 NBPF20 SFN

1.98e-0443068635044719
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

NOLC1 NOP14 BMS1 PDCD11 DDX27 TOP2A

1.98e-0443068638172120
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

SERBP1 POLR2A BMS1 MAP3K20 MIDEAS DDX27 TOP2A

1.99e-0461568731048545
Pubmed

Regulation and function of IKK and IKK-related kinases.

MALT1 TAB2

2.05e-041168217047224
InteractionCEBPB interactions

NOLC1 SERBP1 HYOU1 ZBTB17 ACAT1 POLR2A BMS1 HTATSF1 ASXL2 LAS1L IRAG1 TTC1 POLR1G ANKHD1 PRPF40A ENSA DDX27 TOP2A DYNC1I2 SFN

1.85e-0814436620int:CEBPB
InteractionZBTB2 interactions

NOLC1 SERBP1 NOP14 CHD5 BMS1 DDX54 PDCD11 LAS1L SHTN1 PRPF40A ENSA TOP2A

2.19e-084506612int:ZBTB2
InteractionSIRT7 interactions

NOLC1 SERBP1 NOP14 HYOU1 ACAT1 POLR2A BMS1 DDX54 PDCD11 LAS1L ANKHD1 PRPF40A DDX27 TOP2A

1.01e-077446614int:SIRT7
InteractionNOP56 interactions

NOLC1 OPTN SERBP1 NOP14 HYOU1 BMS1 DDX54 PDCD11 LAS1L POLR1G DDX27 TOP2A

2.86e-075706612int:NOP56
InteractionNAA40 interactions

NOLC1 OPTN SERBP1 ANK2 POLR2A ENAH FAM169A HTATSF1 BTAF1 TTC1 ANKHD1 SHTN1 PRPF40A ENSA TOP2A

4.59e-079786615int:NAA40
InteractionSRPK2 interactions

NOLC1 LMO7 POLR2A BMS1 DDX54 MAP3K20 HTATSF1 PDCD11 LAS1L PRPF40A ENSA DDX27 TOP2A

4.71e-077176613int:SRPK2
InteractionPOLR1G interactions

NOLC1 NOP14 POLR2A BMS1 DDX54 PDCD11 LAS1L CLSPN POLR1G DDX27 TOP2A

4.94e-074896611int:POLR1G
InteractionPARP1 interactions

NOLC1 TRIM33 NOP14 HYOU1 LMO7 POLR2A BMS1 DDX54 FAM169A PDCD11 ASXL2 BTAF1 LAS1L CLSPN PRPF40A DDX27 TOP2A

7.59e-0713166617int:PARP1
InteractionMEN1 interactions

NOLC1 KMT2C NOP14 LMO7 POLR2A BMS1 DDX54 PDCD11 BTAF1 LAS1L POLR1G MIDEAS PRPF40A DDX27 TOP2A

8.73e-0710296615int:MEN1
InteractionH2BC12 interactions

NOLC1 TRIM33 SERBP1 NOP14 CHD5 POLR2A ASXL2 DDX27 TOP2A

1.01e-06322669int:H2BC12
InteractionNIFK interactions

NOLC1 SERBP1 NOP14 BMS1 DDX54 PDCD11 LAS1L TTC1 POLR1G DDX27

1.31e-064316610int:NIFK
InteractionDHX40 interactions

NOP14 BMS1 DDX54 PDCD11 HERC1 LAS1L CLSPN DDX27

1.50e-06249668int:DHX40
InteractionPIAS4 interactions

OPTN SERBP1 BTAF1 PRPF40A ZHX1 KAT14 TOP2A

1.55e-06173667int:PIAS4
InteractionZNF330 interactions

NOLC1 NOP14 BMS1 DDX54 FAM169A PDCD11 LAS1L MIDEAS DDX27 TOP2A

1.78e-064466610int:ZNF330
InteractionCSNK2A1 interactions

NOLC1 OPTN SERBP1 GAP43 POLR2A BMS1 DDX54 HTATSF1 ASXL2 POLR1G PRPF40A ZHX1 TOP2A SFN

2.05e-069566614int:CSNK2A1
InteractionNUP43 interactions

NOP14 BMS1 FAM169A PDCD11 ASXL2 LAS1L MIDEAS ZHX1 DDX27 TOP2A RYR2

5.33e-066256611int:NUP43
InteractionMALAT1 interactions

POLR2A DDX54 LAS1L ANKHD1 PRPF40A SFN

6.25e-06139666int:MALAT1
InteractionFBL interactions

NOLC1 SERBP1 NOP14 BMS1 DDX54 NAP1L2 PDCD11 LAS1L SHTN1 DDX27 TOP2A

6.58e-066396611int:FBL
InteractionTNIP1 interactions

NOLC1 OPTN SERBP1 OFD1 LMO7 CHD5 DDX54 MAP3K20 PDCD11 LAS1L POLR1G SHTN1 PRPF40A DDX27 TOP2A

6.91e-0612176615int:TNIP1
InteractionIPO5 interactions

TRIM33 SERBP1 NOP14 OFD1 CRYBG3 LAS1L POLR1G DYNC1I2 SFN

7.85e-06414669int:IPO5
InteractionERG interactions

NOLC1 TRIM33 KMT2C POLR2A ASXL2 MIDEAS PRPF40A

8.27e-06223667int:ERG
InteractionSNIP1 interactions

NOLC1 NOP14 POLR2A BMS1 DDX54 LAS1L PRPF40A DDX27 NBPF20

8.32e-06417669int:SNIP1
InteractionZC3H3 interactions

NOP14 BMS1 DDX54 PDCD11 ANKHD1 MIDEAS DDX27

9.02e-06226667int:ZC3H3
InteractionCHD4 interactions

NOLC1 SERBP1 NOP14 CHD5 BMS1 DDX54 HTATSF1 PDCD11 LAS1L ANKHD1 PRPF40A DDX27 TOP2A

9.13e-069386613int:CHD4
InteractionH1-2 interactions

OPTN SERBP1 ANK2 POLR2A BMS1 DDX54 PDCD11 ASXL2 PRPF40A DDX27 SFN

9.72e-066666611int:H1-2
InteractionBAP1 interactions

KMT2C SERBP1 HYOU1 LMO7 ENAH TAB2 ASXL2 TTC1 POLR1G ANKHD1 SHTN1 PRPF40A ENSA DYNC1I2 SFN

1.73e-0513146615int:BAP1
InteractionPOLR1E interactions

NOLC1 NOP14 POLR2A BMS1 DDX54 PDCD11 LAS1L POLR1G

1.83e-05350668int:POLR1E
InteractionFGFBP1 interactions

NOP14 BMS1 DDX54 PDCD11 POLR1G ANKHD1 DDX27

2.07e-05257667int:FGFBP1
InteractionFZR1 interactions

TRIM33 SERBP1 NOP14 ANK2 BMS1 DDX54 FAM169A PDCD11 BTAF1 PPP1R15A LAS1L CLSPN TTC1 DDX27

2.10e-0511726614int:FZR1
InteractionRNF2 interactions

NOLC1 NOP14 HYOU1 LMO7 POLR2A BMS1 PDCD11 LAS1L POLR1G DDX27 TOP2A DYNC1I2

2.13e-058666612int:RNF2
InteractionLHX1 interactions

KMT2C BMS1 PDCD11 LAS1L DDX27

2.21e-05103665int:LHX1
InteractionDDX23 interactions

NOLC1 NOP14 BMS1 DDX54 PDCD11 LAS1L PRPF40A DDX27 TOP2A

2.54e-05480669int:DDX23
InteractionZNF467 interactions

NOP14 BMS1 DDX54 PDCD11 POLR1G DDX27

2.64e-05179666int:ZNF467
InteractionADARB1 interactions

SERBP1 ANK2 CHD5 BMS1 DDX54 PDCD11 LAS1L DDX27 TOP2A

2.94e-05489669int:ADARB1
InteractionCHD3 interactions

NOLC1 SERBP1 CHD5 DDX54 HTATSF1 PDCD11 LAS1L PRPF40A ZHX1 DDX27 TOP2A

3.18e-057576611int:CHD3
InteractionSRP68 interactions

TRIM33 SERBP1 BMS1 DDX54 PDCD11 LAS1L DDX27 TOP2A

3.35e-05381668int:SRP68
InteractionAPOBEC3C interactions

SERBP1 BMS1 DDX54 PDCD11 POLR1G DDX27

3.37e-05187666int:APOBEC3C
InteractionSRPK3 interactions

BMS1 DDX54 PDCD11 LAS1L DDX27 TOP2A

3.69e-05190666int:SRPK3
InteractionIWS1 interactions

NOLC1 POLR2A HTATSF1 POLR1G TOP2A

3.91e-05116665int:IWS1
InteractionTCOF1 interactions

NOLC1 KMT2C SERBP1 OFD1 OGFOD1 HTATSF1 POLR1G

4.68e-05292667int:TCOF1
InteractionWDR5 interactions

KMT2C SERBP1 HYOU1 ACAT1 LMO7 DDX54 PDCD11 ASXL2 CLSPN ANKHD1 KAT14 DDX27 DYNC1I2

4.92e-0511016613int:WDR5
InteractionDNAJC9 interactions

NOLC1 SERBP1 NOP14 HYOU1 BMS1 PDCD11 DDX27

5.10e-05296667int:DNAJC9
InteractionRPS24 interactions

NOLC1 SERBP1 NOP14 BMS1 DDX54 PDCD11 LAS1L DDX27 TOP2A

5.41e-05529669int:RPS24
InteractionDOT1L interactions

SERBP1 NOP14 LMO7 BMS1 DDX54 PDCD11 LAS1L POLR1G PRPF40A DDX27 TOP2A

5.69e-058076611int:DOT1L
InteractionHGH1 interactions

SERBP1 NOP14 PDCD11 DDX27

6.11e-0565664int:HGH1
InteractionH2BC13 interactions

NOLC1 SERBP1 NOP14 POLR2A HERC1 TOP2A

6.43e-05210666int:H2BC13
InteractionPRC1 interactions

NOLC1 SERBP1 LMO7 CHD5 POLR2A BMS1 DDX54 PDCD11 HERC1 PRPF40A DDX27 TOP2A

6.61e-059736612int:PRC1
InteractionWWTR1 interactions

LMO7 POLR2A ENAH PDCD11 ANKHD1 SHTN1 PRPF40A TOP2A

6.87e-05422668int:WWTR1
InteractionCDK9 interactions

TRIM33 SERBP1 LMO7 POLR2A BMS1 HTATSF1 PDCD11 CLSPN PRPF40A DDX27

7.29e-056856610int:CDK9
InteractionUSP7 interactions

TRIM33 SERBP1 OFD1 GAP43 TSBP1 DDX54 NAP1L2 HERC1 LAS1L CLSPN POLR1G PRPF40A TOP2A SFN

7.30e-0513136614int:USP7
InteractionSURF6 interactions

OPTN SERBP1 NOP14 BMS1 DDX54 PDCD11 POLR1G DDX27

7.34e-05426668int:SURF6
InteractionHECTD1 interactions

NOLC1 SERBP1 NOP14 BMS1 DDX54 PDCD11 LAS1L POLR1G PRPF40A DDX27 TOP2A SFN

7.36e-059846612int:HECTD1
InteractionKMT2A interactions

KMT2C POLR2A PPP1R15A LAS1L POLR1G KAT14 SFN

7.39e-05314667int:KMT2A
InteractionSRP9 interactions

OPTN SERBP1 NOP14 POLR2A DDX54 HTATSF1 LAS1L CLSPN

7.46e-05427668int:SRP9
InteractionCOIL interactions

NOLC1 NOP14 BMS1 DDX54 HTATSF1 PDCD11 LAS1L POLR1G TOP2A

7.50e-05552669int:COIL
InteractionRBM19 interactions

NOP14 BMS1 DDX54 PDCD11 POLR1G DDX27

8.53e-05221666int:RBM19
InteractionSLX4 interactions

TRIM33 SERBP1 NOP14 POLR2A DDX54 PDCD11 CLSPN ANKHD1 KAT14

9.83e-05572669int:SLX4
InteractionNLE1 interactions

OPTN NOP14 PDCD11 CLSPN DDX27 TOP2A

1.01e-04228666int:NLE1
InteractionTLX2 interactions

KMT2C DDX54 PDCD11 MIDEAS DDX27

1.02e-04142665int:TLX2
InteractionIFI16 interactions

SERBP1 NOP14 POLR2A BMS1 DDX54 PDCD11 LAS1L PRPF40A DDX27 TOP2A

1.03e-047146610int:IFI16
InteractionDDX21 interactions

TRIM33 SERBP1 NOP14 BMS1 DDX54 PDCD11 POLR1G PRPF40A DDX27 TOP2A

1.08e-047186610int:DDX21
InteractionRPS16 interactions

SERBP1 NOP14 BMS1 PDCD11 ASXL2 LAS1L ANKHD1 DDX27 TOP2A SFN

1.15e-047246610int:RPS16
InteractionELF5 interactions

TRIM33 KMT2C POLR2A MIDEAS PRPF40A

1.21e-04147665int:ELF5
InteractionUSP36 interactions

NOLC1 NOP14 BMS1 DDX54 PDCD11 LAS1L POLR1G DDX27 TOP2A

1.39e-04599669int:USP36
InteractionH3C1 interactions

TRIM33 KMT2C PIEZO2 ANK2 POLR2A DDX54 POLR1G MIDEAS KAT14 DDX27 TOP2A

1.51e-049016611int:H3C1
InteractionDCAF13 interactions

OPTN NOP14 WDR81 PDCD11 PRPF40A DDX27

1.57e-04247666int:DCAF13
InteractionNANOG interactions

TRIM33 KMT2C NOP14 POLR2A LAS1L MIDEAS DDX27 TOP2A

1.70e-04481668int:NANOG
InteractionCTPS1 interactions

TRIM33 SERBP1 NOP14 OFD1 PDCD11 DDX27

1.75e-04252666int:CTPS1
InteractionRPL4 interactions

NOLC1 SERBP1 BMS1 DDX54 PDCD11 POLR1G PRPF40A DDX27 TOP2A SFN

1.78e-047646610int:RPL4
InteractionSNRNP40 interactions

NOP14 BMS1 HTATSF1 PDCD11 LAS1L MIDEAS PRPF40A DDX27 TOP2A

2.21e-04637669int:SNRNP40
InteractionHDAC1 interactions

NOLC1 LMO7 CHD5 TAB2 CRYBG3 POLR1G ANKHD1 SHTN1 MIDEAS ZHX1 KAT14 TOP2A

2.25e-0411086612int:HDAC1
InteractionUTP4 interactions

NOLC1 NOP14 BMS1 LAS1L CLSPN

2.37e-04170665int:UTP4
InteractionH2AC4 interactions

KMT2C SERBP1 DDX54 PDCD11 ANKHD1 MIDEAS DDX27 TOP2A

2.39e-04506668int:H2AC4
InteractionGRM2 interactions

KMT2C SERBP1 DDX54 PDCD11 LAS1L DDX27 TOP2A

2.44e-04381667int:GRM2
InteractionCBX3 interactions

TRIM33 NOP14 CHD5 POLR2A HTATSF1 ASXL2 BTAF1 CLSPN TOP2A

2.45e-04646669int:CBX3
InteractionKLF9 interactions

BMS1 PDCD11 ANKHD1 DDX27

2.46e-0493664int:KLF9
InteractionH1-4 interactions

NOLC1 SERBP1 NOP14 BMS1 DDX54 PDCD11 ASXL2 PRPF40A DDX27

2.74e-04656669int:H1-4
InteractionRIOX2 interactions

SERBP1 DDX54 ASXL2 FAM9C

2.78e-0496664int:RIOX2
InteractionHNF4A interactions

TRIM33 KMT2C ASXL2 MIDEAS ZHX1 KAT14

2.80e-04275666int:HNF4A
InteractionSLX9 interactions

SERBP1 NOP14 DDX54 LAS1L POLR1G

2.86e-04177665int:SLX9
InteractionDCPS interactions

SERBP1 BMS1 DDX54 PDCD11 LAS1L PRPF40A TOP2A

2.99e-04394667int:DCPS
InteractionGLI2 interactions

ZBTB17 OFD1 HERC1 ANKHD1

3.13e-0499664int:GLI2
InteractionRPS14 interactions

NOLC1 SERBP1 NOP14 BMS1 DDX54 PDCD11 DDX27 TOP2A

3.22e-04529668int:RPS14
InteractionRPL15 interactions

NOLC1 SERBP1 BMS1 DDX54 PDCD11 POLR1G TOP2A DYNC1I2

3.26e-04530668int:RPL15
InteractionPDCD11 interactions

OPTN NOP14 BMS1 DDX54 PDCD11 POLR1G DDX27

3.53e-04405667int:PDCD11
InteractionLMTK3 interactions

HYOU1 ACAT1 DDX54 DDX27

3.64e-04103664int:LMTK3
InteractionSMC5 interactions

NOLC1 TRIM33 SERBP1 ACAT1 POLR2A HTATSF1 PDCD11 LAS1L MIDEAS PRPF40A TOP2A

3.72e-0410006611int:SMC5
InteractionMNDA interactions

BMS1 DDX54 PDCD11 LAS1L DDX27

3.78e-04188665int:MNDA
InteractionCHMP4C interactions

NOLC1 SERBP1 HYOU1 LMO7 PDCD11 PRPF40A DDX27 TOP2A SFN

3.84e-04687669int:CHMP4C
InteractionPELP1 interactions

NOLC1 HTATSF1 LAS1L POLR1G PRPF40A

3.87e-04189665int:PELP1
InteractionRNF113A interactions

NOLC1 SERBP1 DDX54 LAS1L POLR1G ANKHD1 MIDEAS PRPF40A DDX27

4.05e-04692669int:RNF113A
InteractionACTC1 interactions

NOLC1 SERBP1 LMO7 ENAH HTATSF1 NUTM2F SHTN1 PRPF40A KAT14

4.14e-04694669int:ACTC1
InteractionNOP2 interactions

NOLC1 BMS1 DDX54 PDCD11 POLR1G DDX27 TOP2A

4.14e-04416667int:NOP2
InteractionEZR interactions

NOLC1 TRIM33 ANK2 LMO7 ENAH MACROD2 OGFOD1 DYNC1I2

4.33e-04553668int:EZR
InteractionFGF8 interactions

BMS1 DDX54 PDCD11 ANKHD1

4.35e-04108664int:FGF8
InteractionDIS3 interactions

TRIM33 SERBP1 NOP14 ZBTB17 DDX27

4.36e-04194665int:DIS3
InteractionKLF12 interactions

DDX54 PDCD11 ZHX1 KAT14 DDX27

4.36e-04194665int:KLF12
InteractionCDC5L interactions

NOLC1 NOP14 LMO7 POLR2A ENAH BMS1 BTAF1 LAS1L PRPF40A TOP2A

4.38e-048556610int:CDC5L
InteractionIMPDH2 interactions

SERBP1 OFD1 ASXL2 CRYBG3 SHTN1 TOP2A SFN

4.39e-04420667int:IMPDH2
InteractionSRSF4 interactions

SERBP1 BMS1 DDX54 HTATSF1 DDX27 SFN

4.44e-04300666int:SRSF4
GeneFamilyPHD finger proteins

TRIM33 KMT2C CHD5

9.58e-049039388
GeneFamilyWD repeat domain containing

CFAP251 WDR81 HERC1 DYNC1I2

2.38e-03262394362
GeneFamilyDEAD-box helicases

DDX54 DDX27

3.70e-0342392499
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

TRIM33 OPTN ZBTB17 OFD1 POLR2A ENAH FAM169A PGBD1 TAB2 ASXL2 CLSPN PRPF40A KAT14 DYNC1I2

2.46e-0512526614facebase_RNAseq_e10.5_MaxArch_2500_K3
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP251 LMO7 ENAH ODAD2 CLSPN TOP2A

5.54e-07196686af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP251 LMO7 ENAH ODAD2 CLSPN TOP2A

5.54e-071966866d02d494196e3f857d53eea46d9419690d43beca
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

ANK2 GAP43 LMO7 CHD5 DYNC1I2 RYR2

6.05e-071996861b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

ANK2 GAP43 LMO7 CHD5 DYNC1I2 RYR2

6.05e-071996864bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

ANK2 GAP43 LMO7 MACROD2 SHTN1 RYR2

6.23e-07200686db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

ANK2 GAP43 LMO7 MACROD2 SHTN1 RYR2

6.23e-0720068630a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

ENAH MACROD2 IRAG1 RYR2 PDZRN4

1.02e-0518868534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHD5 MAP3K20 IRAG1 RYR2 PDZRN4

1.04e-051896857fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

ANK2 LMO7 MACROD2 RYR2 SLC5A1

1.04e-051896859c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHD5 MAP3K20 IRAG1 RYR2 PDZRN4

1.04e-0518968506b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 EFHC1 RSPH4A SAMD15 TOP2A

1.10e-05191685a6c9df4cb4d09e0a91b3c8d7f3e091a7e95e6471
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ENAH MAP3K20 IRAG1 RYR2 PDZRN4

1.13e-05192685bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ENAH MAP3K20 IRAG1 RYR2 PDZRN4

1.13e-05192685b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 EFHC1 RSPH4A ODAD2 SAMD15

1.15e-05193685e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

PIEZO2 ANK2 ENAH IRAG1 RYR2

1.18e-0519468503a269f75a481ea54aea8e6444605db8d6df493d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENAH MAP3K20 IRAG1 RYR2 PDZRN4

1.18e-051946855c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENAH MAP3K20 IRAG1 RYR2 PDZRN4

1.18e-05194685ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

ANK2 LMO7 MACROD2 MAP3K20 RYR2

1.21e-0519568575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 EFHC1 RSPH4A ENAH ODAD2

1.21e-0519568534e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENAH MAP3K20 IRAG1 RYR2 PDZRN4

1.24e-051966851522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP251 EFHC1 RSPH4A ODAD2 SAMD15

1.24e-0519668527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENAH MAP3K20 IRAG1 RYR2 PDZRN4

1.24e-051966851c8294014713684b50885e638668f2ce75f357f0
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 EFHC1 RSPH4A ODAD2 SAMD15

1.27e-051976856865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

POLR2A CLSPN PRPF40A DDX27 TOP2A

1.27e-051976850fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP251 RSPH4A ODAD2 SAMD15 TOP2A

1.31e-05198685f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

TRIM33 ANK2 ENAH SHTN1 PDZRN4

1.31e-05198685de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

CFAP251 CHD5 CLSPN TOP2A SFN

1.34e-05199685e222b90caf45904d8f763574e7b6aac13333df92
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

OPTN ANK2 GAP43 CHD5 SHTN1

1.34e-051996855de2a32bc2e9c752eb19a013b1807949153728fc
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Neuronal|GW13 / Sample Type, Dataset, Time_group, and Cell type.

GAP43 SHTN1 DYNC1I2

3.13e-0540683a55d9861170f41049748cd093d3d680855553d1d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Neuronal-Neurons|GW13 / Sample Type, Dataset, Time_group, and Cell type.

GAP43 SHTN1 DYNC1I2

3.13e-05406837d7dc8dd5b095b7e3a83cbf840c4ee4f650bbc7c
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-Neuronal|GW12 / Sample Type, Dataset, Time_group, and Cell type.

GAP43 ACAT1 SHTN1

3.63e-05426839485f945664a7480ef019a65bdc8a570d3dda597
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLSPN NUTM2F ZHX1 NBPF20

6.09e-051396847c02caed5b9baf233bd6fb9a453708b3e157c790
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLSPN TOP2A ERICH4 SFN

7.98e-05149684a6406c4c9404271a2f4c615c6cd3265b2d759b12
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAP43 POLR2A NAP1L2 ODAD2

9.07e-051546842d98bb7a784fc3215e0d4a1670d662e5df4716c3
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAP43 POLR2A NAP1L2 ODAD2

9.07e-051546840dec222101530f1727184dbb7c03969d3884f111
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

ENAH IRAG1 RYR2 PDZRN4

1.05e-04160684fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellBAL-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

CFAP251 IRAG1 CLSPN TOP2A

1.24e-041676846c5aa9077ae7eb8887269d405972bd5b31596b19
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ANK2 PGBD1 CLSPN TOP2A

1.24e-041676843461d14e36f09ddc6ee5549ca4797e16d3f37fcc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLSPN SHTN1 SAMD15 TOP2A

1.27e-041686849b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLSPN SHTN1 SAMD15 TOP2A

1.27e-041686844b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGBD1 HTATSF1 CRYBG3 ZHX1

1.27e-04168684d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLSPN SHTN1 SAMD15 TOP2A

1.27e-04168684c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACROD2 IRAG1 RYR2 PDZRN4

1.36e-041716844ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

ENAH IRAG1 RYR2 PDZRN4

1.39e-04172684c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 EFHC1 RSPH4A ODAD2

1.39e-04172684187ae91148d293537afc77e10da2b64302322224
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CHD5 IRAG1 RYR2 PDZRN4

1.42e-04173684a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHD5 MAP3K20 IRAG1 PDZRN4

1.48e-04175684d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHD5 MAP3K20 IRAG1 PDZRN4

1.48e-04175684454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANK2 MAP3K20 SHTN1 SAMD15

1.55e-04177684f7a2e6b5e82f0565f8030696944f33c544233b94
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANK2 MAP3K20 SHTN1 SAMD15

1.55e-04177684ef02ee75db36a92dda889efb6fad1193efbc4be4
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MALT1 OPTN ODAD2 SFN

1.58e-041786849b932b677ae05ac6e12cd6ce97789f8c10e4790b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 EFHC1 RSPH4A ENAH

1.65e-041806841f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLSPN POLR1G TOP2A SFN

1.69e-04181684e0c46e2d52c97893e5894a51d2699e8a8a11eefc
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK2 MAP3K20 RYR2 SLC5A1

1.69e-04181684719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

LMO7 ENAH MACROD2 SFN

1.69e-041816846d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OFD1 LMO7 DDX54 PDCD11

1.69e-04181684709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

LMO7 ENAH MACROD2 SFN

1.72e-04182684759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

LMO7 ENAH MAP3K20 RYR2

1.72e-04182684287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 EFHC1 RSPH4A ODAD2

1.72e-04182684e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENAH MAP3K20 PPP1R15A IRAG1

1.72e-04182684728a2152c166551ac229370c0900fe2bc426ea9b
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

LMO7 ENAH MACROD2 SFN

1.72e-04182684caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 EFHC1 RSPH4A ODAD2

1.72e-04182684e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCelldroplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOLC1 OPTN MAP3K20 PDCD11

1.76e-0418368492ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

LMO7 ENAH MACROD2 SFN

1.76e-041836840f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCelldroplet-Marrow-nan-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOLC1 OPTN MAP3K20 PDCD11

1.76e-0418368424db9cc717e651586317c6a8e03a3401651273c1
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ENAH MACROD2 IRAG1 PDZRN4

1.76e-04183684cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

PIEZO2 GAP43 ENAH IRAG1

1.80e-041846840b336489c10e8c3c957795dd845454f03404382b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL3 RSPH4A TSBP1 ODAD2

1.80e-04184684264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 EFHC1 RSPH4A ODAD2

1.80e-0418468407c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL3 RSPH4A TSBP1 ODAD2

1.80e-04184684d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL3 RSPH4A TSBP1 ODAD2

1.80e-0418468422010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 MAP3K20 IRAG1 PDZRN4

1.83e-0418568451dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K20 PPP1R15A IRAG1 ERICH4

1.83e-041856845f5df92b328be396941b5812d00454b5ff927d30
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 EFHC1 RSPH4A ODAD2

1.83e-04185684f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K20 PPP1R15A IRAG1 ERICH4

1.83e-0418568498547c1b1828b76da810ed86082182afaaacdb3f
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ANK2 LMO7 RYR2 SLC5A1

1.83e-041856846baccb26f999145e51b91d94315bf8d4655bef31
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 MAP3K20 IRAG1 PDZRN4

1.83e-04185684a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAP43 LMO7 RYR2 PDZRN4

1.87e-0418668484ba666237c18189d7e7556bd92dd953af733c00
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 RSPH4A ODAD2 SAMD15

1.87e-0418668476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM169A RYR2 SLC5A1 PDZRN4

1.87e-041866848eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACROD2 IRAG1 RYR2 PDZRN4

1.87e-041866844780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TRIM33 ASXL2 IRAG1 PRPF40A

1.87e-0418668403db813598b67b1e08f759758a1c2023396921fa
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

ENAH IRAG1 RYR2 PDZRN4

1.91e-04187684464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ANK2 LMO7 SFN SLC5A1

1.91e-04187684f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 IRAG1 RYR2 PDZRN4

1.91e-0418768448bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 IRAG1 RYR2 PDZRN4

1.91e-04187684958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 IRAG1 RYR2 PDZRN4

1.95e-04188684b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENAH IRAG1 RYR2 PDZRN4

1.95e-0418868461f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCelldroplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENAH IRAG1 RYR2 PDZRN4

1.95e-041886847553ef7de3575af4cf34704b405b551c1af8eb83
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFAP251 EFHC1 RSPH4A ODAD2

1.95e-041886845ba5cbb403518026e9040379fb5d99339ea977d8
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP251 TTLL3 RSPH4A ODAD2

1.99e-04189684b55de812043b670cbde810d7d42f45909b6d66ef
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP251 EFHC1 RSPH4A ODAD2

1.99e-0418968457ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP251 EFHC1 RSPH4A ODAD2

1.99e-04189684ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EFHC1 ANK2 RSPH4A ODAD2

1.99e-04189684cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACROD2 IRAG1 RYR2 PDZRN4

1.99e-04189684975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 IRAG1 RYR2 PDZRN4

1.99e-04189684127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellEpithelial-D_(Ciliated)|World / shred on cell class and cell subclass (v4)

CFAP251 TTLL3 RSPH4A ODAD2

1.99e-041896840bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP251 TTLL3 RSPH4A ODAD2

1.99e-0418968438cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ENAH MACROD2 IRAG1 PDZRN4

1.99e-041896846b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 IRAG1 RYR2 PDZRN4

1.99e-04189684fac5c291a9a87418bb0878c3d624829bdbf1f428
ComputationalNeighborhood of MCM5

SERBP1 NOP14 LAS1L TOP2A

8.12e-0561414GNF2_MCM5
DiseasePrimary Ciliary Dyskinesia

OFD1 RSPH4A ODAD2

1.41e-0447633C4551720
DiseaseVENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)

ANK2 RYR2

2.00e-0410632C1631597
DiseaseYu-Zhi constitution type

PIEZO2 MACROD2

4.63e-0415632EFO_0007638
DiseaseColorectal Carcinoma

KMT2C TTLL3 ANK2 LMO7 CHD5 LAS1L PDZRN4

7.30e-04702637C0009402
Diseasebeverage consumption measurement

MACROD2 DYNC1I2 RYR2

7.55e-0483633EFO_0010088
DiseaseMyopia

POLR2A ENAH PGBD1 POLR1G RYR2

1.39e-03385635HP_0000545
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

NOLC1 MACROD2 MAP3K20 BTAF1 HERC1 SHTN1 RYR2

1.56e-03801637EFO_0003888, EFO_0007052, MONDO_0002491
Diseasecentral nervous system cancer

PIEZO2 POLR2A

2.00e-0331632EFO_0000326

Protein segments in the cluster

PeptideGeneStartEntry
EEKQDTQEKEGILPE

ENSA

16

O43768
KAEEKEPIETQQNGD

CHD5

1671

Q8TDI0
EGSVEETKEEPTEIK

CRYBG3

1901

Q68DQ2
EQKSNEEGSEEKGPE

SFN

66

P31947
QNEDIEKEVKEEIDP

BMS1

801

Q14692
AKEGSEPKEQEDLQE

DDX27

146

Q96GQ7
TGDEQESVTVKEEPQ

ASXL2

1186

Q76L83
KEVEDPQQESKDDTI

CFAP251

31

Q8TBY9
VEQPKKQEEEEGTTD

PDZRN4

526

Q6ZMN7
DDEEDQKKQPVQKGV

NOLC1

136

Q14978
ATGEENKEEEDPKGI

NAP1L2

226

Q9ULW6
PSVDQKQIEEQKEEE

OFD1

866

O75665
TQEEPGKSEEEKDSE

ANK2

2726

Q01484
ENKENEVEEVKEEGP

SERBP1

271

Q8NC51
QTDPEPEENETKKES

OGFOD1

416

Q8N543
SVQNPEKTKEGLEEE

ABCC10

836

Q5T3U5
QEEPKLEEQNGSKVE

KMT2C

3731

Q8NEZ4
EDTVEDKQEVNVGKP

MALT1

696

Q9UDY8
ESEEKGDVEQKPESE

HERC1

2421

Q15751
KQPEKEEEEEAGESV

DDX54

631

Q8TDD1
ETDQKKEAVAPVQEE

DYNC1I2

36

Q13409
QDLKEEEEEQKSESP

IRAG1

791

Q9Y6F6
GPEQIKQEVESEEEK

KAT14

406

Q9H8E8
QEEVVHEDQGKKPQD

LMO7

1326

Q8WWI1
EEQGSVNDVKEEEKE

LAS1L

556

Q9Y4W2
VESEEENEKPAKEQR

NOP14

386

P78316
QETVADFTPKKEEEE

PRPF40A

366

O75400
NKESEEEVGPTKESE

HTATSF1

526

O43719
GSKDEPGEQVELKEE

HYOU1

611

Q9Y4L1
FEVQDEKSGEVDPKE

BTAF1

126

O14981
SSKEEEEDQEPQRKQ

ERICH4

96

A6NGS2
PQQEKQDGEKESELE

FAM169A

411

Q9Y6X4
IKDSGGEPEENEEKI

MAP3K20

421

Q9NYL2
EGEEEVPEIQEKEEQ

MIDEAS

941

Q6PJG2
ESKQTEKDPGVQELE

EFHC1

546

Q5JVL4
TTDPKEEIKQVSEDD

LAS2

316

Q8IYD9
ETEQKEDKGEDSEPV

ENAH

466

Q8N8S7
EEGDGEKEEQIKIFQ

FAM9C

136

Q8IZT9
PKSSEEEGQKDEEVL

BMP2KL

6

Q5H9B9
KERVSEDDETQPEKG

SAMD15

521

Q9P1V8
ANKEESEKERPEEQG

RYR2

4216

Q92736
KNPGEEKAEEEGVAE

PPP1R15A

156

O75807
STEKENDEEKGPETV

OPTN

281

Q96CV9
IPLTEDQEEKEGEKA

MACROD2

371

A1Z1Q3
EKGKVEQPQEEDGIT

NUTM2F

421

A1L443
SPKQEKENQEELGET

RSPH4A

6

Q5TD94
DQVKVKQEPGTEDEI

TRIM33

771

Q9UPN9
IIKTPKTQDTEDDEG

TAB2

651

Q9NYJ8
EENIEAVDETKPKES

GAP43

206

P17677
DRTKKDQEEEEDQGP

NBPF20

1111

P0DPF2
DRTKKDQEEEEDQGP

NBPF20

2331

P0DPF2
DRTKKDQEEEEDQGP

NBPF20

3551

P0DPF2
DRTKKDQEEEEDQGP

NBPF20

4621

P0DPF2
DRTKKDQEEEEDQGP

NBPF20

4771

P0DPF2
ETTVKSEEVDKNGQP

ODAD2

76

Q5T2S8
KQQDATVEPETEVVG

POLR1G

391

O15446
VAEKDPTQHKEDEGE

SHTN1

596

A0MZ66
TVKGQPDVVVKEDEE

ACAT1

241

P24752
ENEDGLVKVKEEDPT

PGBD1

11

Q96JS3
QEEDEENKPKENSEL

ANKHD1

1471

Q8IWZ3
ETDEKVEEPEQQNKS

CLSPN

466

Q9HAW4
EGKEEAEETNVLPKE

PDCD11

1506

Q14690
VEQPEGDEDLTKEKG

POLR2A

166

P24928
EVKIGSQENEEKDEE

PIEZO2

616

Q9H5I5
NSVEDVPEEKENEIK

ZHX1

201

Q9UKY1
PKEATEVKDQVETQE

nan

81

A8MX80
VEEEASGDKQPKKQE

TTLL3

171

Q9Y4R7
PKEATEVKDQVETQG

nan

51

A8MV72
KEAQQKVPDEEENEE

TOP2A

1091

P11388
PKEATEVKDQVETQG

nan

81

Q8N9G6
PARKGEEEQKEQEEQ

ZBTB17

226

Q13105
PKEATEVKDQVETQG

nan

81

A8MUI8
EEPKEATEVKDQVET

nan

116

Q5PR19
EEENIQEGPKETIEI

SLC5A1

576

P13866
EPAEEVEKQQEGEEK

TSPY26P

111

Q9H489
GQVEKTEADVPKEQE

TSBP1

426

Q5SRN2
EEEPGADKVENKSNE

TTC1

71

Q99614
EEALPEQSEGKEQKI

WDR81

1206

Q562E7