Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF93 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZNF722 ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 DMRT2 NFATC3 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF724 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 ZNF99 ZNF730	1.12e-11	1244	108	29	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF93 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZNF722 ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 DMRT2 NFATC3 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF724 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 ZNF99 ZNF730	1.89e-11	1271	108	29	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZNF722 ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 DMRT2 NFATC3 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF724 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 ZNF99 ZNF730	1.01e-10	1459	108	30	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZSCAN5A ZNF722 ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 DMRT2 NFATC3 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF724 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 ZNF99 ZNF730	2.32e-10	1412	108	29	GO:0000981
GeneOntologyMolecularFunction	store-operated calcium channel activity	TRPC7 TRPC3 TRPC6	3.27e-05	12	108	3	GO:0015279
GeneOntologyMolecularFunction	inositol 1,4,5 trisphosphate binding	TRPC7 TRPC3 TRPC6	5.36e-05	14	108	3	GO:0070679
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF93 ZNF493 FEZF2 NFATC3 ZNF43 SNAI2 ZFHX3 ZNF85 ZNF99	6.07e-05	320	108	9	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZNF93 ZNF493 FEZF2 NFATC3 ZNF43 SNAI2 ZFHX3 ZNF85 ZNF99	7.00e-05	326	108	9	GO:0001217
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF18A SMCHD1 RNF213 CHD8 ATP9B AK9 ATP8B1 ATP8A1 SMC3 DNAH5	1.40e-04	441	108	10	GO:0016887
GeneOntologyMolecularFunction	phosphatidylserine flippase activity	ATP8B1 ATP8A1	2.87e-04	5	108	2	GO:0140346
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF18A MYO5A SMC3 DNAH5 KLC1	4.54e-04	118	108	5	GO:0003774
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP9B ATP8B1 ATP8A1	4.57e-04	28	108	3	GO:0140326
GeneOntologyMolecularFunction	ATP-dependent activity	KIF18A MYO5A SMCHD1 RNF213 CHD8 ATP9B AK9 ATP8B1 ATP8A1 SMC3 DNAH5	4.93e-04	614	108	11	GO:0140657
GeneOntologyMolecularFunction	aminophospholipid flippase activity	ATP8B1 ATP8A1	5.98e-04	7	108	2	GO:0015247
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF493 FEZF2 ZNF594 ZNF600 DMRT2 NFATC3 ZNF43 PLAG1 ZNF85 ZNF99	9.18e-04	560	108	10	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF493 FEZF2 ZNF594 ZNF600 DMRT2 NFATC3 ZNF43 PLAG1 ZNF85 ZNF99	9.95e-04	566	108	10	GO:0001216
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ATP8B1 ATP8A1	1.02e-03	9	108	2	GO:0090556
GeneOntologyBiologicalProcess	sexual reproduction	ADAD1 KIF18A GGNBP2 TRPC7 KMT2B MNS1 CATSPERD SMCHD1 TRPC3 TRPC6 APOB PNLDC1 ATAT1 LEPR MEIOC INSL6 SMC3 CFAP97D1 PIK3CA MROH2B SHISA6	4.43e-06	1312	109	21	GO:0019953
GeneOntologyBiologicalProcess	developmental process involved in reproduction	ADAD1 ZNF93 KIF18A GGNBP2 KMT2B MNS1 CATSPERD SMCHD1 APOB PNLDC1 ATAT1 BMP5 DMRT2 MEIOC INSL6 CFAP97D1 PIK3CA MROH2B PLAG1 SHISA6	6.53e-06	1235	109	20	GO:0003006
GeneOntologyBiologicalProcess	flagellated sperm motility	MNS1 CATSPERD APOB TTLL8 MET INSL6 CFAP97D1 DNAH5	6.57e-06	186	109	8	GO:0030317
GeneOntologyBiologicalProcess	sperm motility	MNS1 CATSPERD APOB TTLL8 MET INSL6 CFAP97D1 DNAH5	8.62e-06	193	109	8	GO:0097722
GeneOntologyBiologicalProcess	cilium movement involved in cell motility	MNS1 CATSPERD APOB TTLL8 MET INSL6 CFAP97D1 DNAH5	1.59e-05	210	109	8	GO:0060294
GeneOntologyBiologicalProcess	cilium-dependent cell motility	MNS1 CATSPERD APOB TTLL8 MET INSL6 CFAP97D1 DNAH5	1.89e-05	215	109	8	GO:0060285
GeneOntologyBiologicalProcess	cilium or flagellum-dependent cell motility	MNS1 CATSPERD APOB TTLL8 MET INSL6 CFAP97D1 DNAH5	1.89e-05	215	109	8	GO:0001539
GeneOntologyBiologicalProcess	microtubule-based process	KIF18A SLK PDCD6IP MNS1 MYO5A CATSPERD APOB STIL ATAT1 TTLL8 MET INSL6 SMC3 CFAP97D1 CEP135 DNAH5 KLC1	3.90e-05	1058	109	17	GO:0007017
GeneOntologyBiologicalProcess	gamete generation	ADAD1 KIF18A GGNBP2 KMT2B MNS1 CATSPERD SMCHD1 APOB PNLDC1 ATAT1 MEIOC INSL6 CFAP97D1 PIK3CA MROH2B SHISA6	5.73e-05	982	109	16	GO:0007276
GeneOntologyBiologicalProcess	microtubule-based movement	KIF18A MNS1 MYO5A CATSPERD APOB TTLL8 MET INSL6 CFAP97D1 DNAH5 KLC1	6.06e-05	493	109	11	GO:0007018
GeneOntologyBiologicalProcess	cilium movement	MNS1 CATSPERD APOB TTLL8 MET INSL6 CFAP97D1 DNAH5	7.46e-05	261	109	8	GO:0003341
GeneOntologyBiologicalProcess	transposable element silencing	ZNF93 ZNF493 ZNF43 ZNF99	1.01e-04	46	109	4	GO:0010526
GeneOntologyBiologicalProcess	retrotransposition	ZNF93 ZNF493 ZNF43 ZNF99	1.20e-04	48	109	4	GO:0032197
GeneOntologyBiologicalProcess	transposition	ZNF93 ZNF493 ZNF43 ZNF99	1.41e-04	50	109	4	GO:0032196
GeneOntologyBiologicalProcess	regulation of locomotor rhythm	LEPR ZFHX3	1.65e-04	4	109	2	GO:1904059
GeneOntologyBiologicalProcess	male gamete generation	ADAD1 KIF18A GGNBP2 MNS1 CATSPERD APOB PNLDC1 ATAT1 MEIOC INSL6 CFAP97D1 MROH2B SHISA6	1.92e-04	762	109	13	GO:0048232
MousePheno	increased chromosomal stability	ZSCAN5DP ZSCAN5A ZSCAN5C	4.59e-06	6	87	3	MP:0010095
Domain	Znf_C2H2/integrase_DNA-bd	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 ZNF99 ZNF730	1.63e-14	694	108	26	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 EEA1 ZNF99 ZNF730	2.69e-14	775	108	27	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 EEA1 ZNF99 ZNF730	2.86e-14	777	108	27	PS00028
Domain	Znf_C2H2-like	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 EEA1 ZNF99 ZNF730	5.11e-14	796	108	27	IPR015880
Domain	Znf_C2H2	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 EEA1 ZNF99 ZNF730	6.70e-14	805	108	27	IPR007087
Domain	ZnF_C2H2	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 EEA1 ZNF99 ZNF730	7.32e-14	808	108	27	SM00355
Domain	zf-C2H2	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF737 ZNF506 ZFHX3 ZNF85 ZNF99 ZNF730	1.33e-13	693	108	25	PF00096
Domain	zf-C2H2_6	ZNF93 ZNF486 ZNF680 ZNF493 FEZF2 ZNF366 ZBTB41 ZIM3 ZNF600 ZNF43 ZNF92 ZNF735 SNAI2 ZNF737 ZNF506 ZNF85 ZNF99 ZNF730	2.52e-13	314	108	18	PF13912
Domain	-	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZNF735 SNAI2 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 ZNF99 ZNF730	6.92e-13	679	108	24	3.30.160.60
Domain	KRAB	ZNF93 ZNF486 ZNF680 ZIM3 ZNF708 ZNF43 ZNF92 ZNF735 ZNF737 ZNF506 ZNF85 ZNF99 ZNF738 ZNF730	1.92e-08	358	108	14	PS50805
Domain	KRAB	ZNF93 ZNF486 ZNF680 ZIM3 ZNF708 ZNF43 ZNF92 ZNF735 ZNF737 ZNF506 ZNF85 ZNF99 ZNF738 ZNF730	1.92e-08	358	108	14	PF01352
Domain	KRAB	ZNF93 ZNF486 ZNF680 ZIM3 ZNF708 ZNF43 ZNF92 ZNF735 ZNF737 ZNF506 ZNF85 ZNF99 ZNF738 ZNF730	2.81e-08	369	108	14	SM00349
Domain	KRAB	ZNF93 ZNF486 ZNF680 ZIM3 ZNF708 ZNF43 ZNF92 ZNF735 ZNF737 ZNF506 ZNF85 ZNF99 ZNF738 ZNF730	2.91e-08	370	108	14	IPR001909
Domain	TRP_dom	TRPC7 TRPC3 TRPC6	3.71e-06	6	108	3	IPR013555
Domain	TRP_2	TRPC7 TRPC3 TRPC6	3.71e-06	6	108	3	PF08344
Domain	TRPC_channel	TRPC7 TRPC3 TRPC6	6.47e-06	7	108	3	IPR002153
Domain	TRP_channel	TRPC7 TRPC3 TRPC6	3.00e-05	11	108	3	IPR004729
Domain	P_typ_ATPase_c	ATP9B ATP8B1 ATP8A1	6.53e-05	14	108	3	IPR032630
Domain	P-type_ATPase_N	ATP9B ATP8B1 ATP8A1	6.53e-05	14	108	3	IPR032631
Domain	P-type_ATPase_IV	ATP9B ATP8B1 ATP8A1	6.53e-05	14	108	3	IPR006539
Domain	PhoLip_ATPase_C	ATP9B ATP8B1 ATP8A1	6.53e-05	14	108	3	PF16212
Domain	PhoLip_ATPase_N	ATP9B ATP8B1 ATP8A1	6.53e-05	14	108	3	PF16209
Domain	SMC_hinge	SMCHD1 SMC3	4.89e-04	6	108	2	PF06470
Domain	SMC_hinge	SMCHD1 SMC3	4.89e-04	6	108	2	SM00968
Domain	SMC_hinge	SMCHD1 SMC3	4.89e-04	6	108	2	IPR010935
Domain	-	NANP ATP9B ATP8B1 ATP8A1	5.14e-04	64	108	4	3.40.50.1000
Domain	-	ATP9B ATP8B1 ATP8A1	8.25e-04	32	108	3	3.40.1110.10
Domain	-	ATP9B ATP8B1 ATP8A1	8.25e-04	32	108	3	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP9B ATP8B1 ATP8A1	1.08e-03	35	108	3	IPR023299
Domain	HAD-like_dom	NANP ATP9B ATP8B1 ATP8A1	1.14e-03	79	108	4	IPR023214
Domain	P_typ_ATPase	ATP9B ATP8B1 ATP8A1	1.17e-03	36	108	3	IPR001757
Domain	ATPase_P-typ_P_site	ATP9B ATP8B1 ATP8A1	1.17e-03	36	108	3	IPR018303
Domain	ATPASE_E1_E2	ATP9B ATP8B1 ATP8A1	1.17e-03	36	108	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP9B ATP8B1 ATP8A1	1.27e-03	37	108	3	IPR008250
Domain	E1-E2_ATPase	ATP9B ATP8B1 ATP8A1	1.27e-03	37	108	3	PF00122
Domain	Znf_FYVE_PHD	KMT2B JADE3 KAT6A ZFYVE26 EEA1	1.64e-03	147	108	5	IPR011011
Domain	DOCK_C	DOCK4 DOCK10	1.76e-03	11	108	2	IPR010703
Domain	DHR-1_domain	DOCK4 DOCK10	1.76e-03	11	108	2	IPR027007
Domain	DHR_2	DOCK4 DOCK10	1.76e-03	11	108	2	PS51651
Domain	DHR_1	DOCK4 DOCK10	1.76e-03	11	108	2	PS51650
Domain	DOCK-C2	DOCK4 DOCK10	1.76e-03	11	108	2	PF14429
Domain	DHR-2	DOCK4 DOCK10	1.76e-03	11	108	2	IPR027357
Domain	DHR-2	DOCK4 DOCK10	1.76e-03	11	108	2	PF06920
Domain	DOCK	DOCK4 DOCK10	1.76e-03	11	108	2	IPR026791
Domain	SCAN_BOX	ZSCAN5DP ZSCAN5A ZSCAN5C	4.61e-03	58	108	3	PS50804
Domain	SCAN	ZSCAN5DP ZSCAN5A ZSCAN5C	4.61e-03	58	108	3	PF02023
Domain	SCAN_dom	ZSCAN5DP ZSCAN5A ZSCAN5C	4.61e-03	58	108	3	IPR003309
Domain	Retrov_capsid_C	ZSCAN5DP ZSCAN5A ZSCAN5C	4.83e-03	59	108	3	IPR008916
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF486 ZNF680 KMT2B ZNF493 TRPC3 KAT6A ZIM3 YWHAH MET ZNF708 ZNF600 ZNF43 ZNF92 ZNF735 ZNF724 ZNF737 ZNF506 ZFHX3 ZNF99 ZNF738 ZNF730	4.39e-06	1387	73	21	M734
Pathway	REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING	TRPC7 TRPC3 TRPC6	1.56e-05	10	73	3	M27330
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	TRPC7 TRPC3 TRPC6	3.67e-05	13	73	3	MM14553
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	TRPC7 TRPC3 TRPC6	7.11e-05	16	73	3	M26945
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	TRPC7 TRPC3 TRPC6	2.82e-04	25	73	3	MM14511
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	TRPC7 TRPC3 TRPC6 ATP9B ATP8B1 ATP8A1	2.96e-04	176	73	6	MM15718
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	TRPC7 TRPC3 TRPC6	3.56e-04	27	73	3	MM15053
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	TRPC7 TRPC3 TRPC6	3.56e-04	27	73	3	M12123
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	TRPC7 TRPC3 TRPC6 ATP9B ATP8B1 ATP8A1	3.65e-04	183	73	6	M997
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	DSP YWHAH MET PIK3CA	3.74e-04	66	73	4	MM15925
Pathway	REACTOME_MET_ACTIVATES_PI3K_AKT_SIGNALING	MET PIK3CA	3.91e-04	6	73	2	M27741
Pathway	REACTOME_MET_ACTIVATES_PI3K_AKT_SIGNALING	MET PIK3CA	3.91e-04	6	73	2	MM15489
Pathway	REACTOME_TRP_CHANNELS	TRPC7 TRPC3 TRPC6	3.98e-04	28	73	3	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPC7 TRPC3 TRPC6	3.98e-04	28	73	3	M27241
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	TRPC7 TRPC3 TRPC6	3.98e-04	28	73	3	M924
Pathway	REACTOME_PLATELET_HOMEOSTASIS	TRPC7 TRPC3 TRPC6 APOB	6.41e-04	76	73	4	MM15051
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF93 ZNF43 ZNF92 ZNF737 ZNF85 ZNF99	8.02e-12	16	113	6	8467795
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF93 ZNF493 ZNF43 ZNF506 ZNF85 ZNF99	4.60e-10	29	113	6	14563677
Pubmed	The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.	ZNF93 ZNF43 ZNF92 ZNF85	7.32e-09	8	113	4	2023909
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF93 ZNF486 ZNF680 ZNF493 ZNF708 ZNF92 ZNF724 ZNF737 ZNF738	8.60e-09	181	113	9	37372979
Pubmed	Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.	TRPC7 TRPC3 TRPC6	3.34e-08	3	113	3	28526717
Pubmed	Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.	ZSCAN5DP ZSCAN5A ZSCAN5C	1.33e-07	4	113	3	31155506
Pubmed	Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.	TRPC7 TRPC3 TRPC6	1.33e-07	4	113	3	30017393
Pubmed	ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression.	ZSCAN5DP ZSCAN5A ZSCAN5C	1.33e-07	4	113	3	27732952
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF93 ZNF493 ZNF43 ZNF99	1.40e-07	15	113	4	15885501
Pubmed	Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits.	TRPC7 TRPC3 TRPC6	3.32e-07	5	113	3	21261756
Pubmed	Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs.	ATP9B ATP8B1 ATP8A1	3.32e-07	5	113	3	9548971
Pubmed	TRPC channels are necessary mediators of pathologic cardiac hypertrophy.	TRPC7 TRPC3 TRPC6	3.32e-07	5	113	3	20351294
Pubmed	Store-operated Ca2+ channels formed by TRPC1, TRPC6 and Orai1 and non-store-operated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes.	TRPC3 TRPC6 NOX1	3.32e-07	5	113	3	18436303
Pubmed	MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.	TRPC7 TRPC3 TRPC6	1.16e-06	7	113	3	15757897
Pubmed	TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis.	TRPC7 TRPC3 TRPC6	1.16e-06	7	113	3	36592529
Pubmed	Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.	TRPC7 TRPC3 TRPC6	1.16e-06	7	113	3	15336983
Pubmed	RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways.	TRPC7 TRPC3 TRPC6	1.16e-06	7	113	3	32350291
Pubmed	TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer.	TRPC7 TRPC3 TRPC6	1.16e-06	7	113	3	38835669
Pubmed	Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes.	TRPC7 TRPC3 TRPC6	1.16e-06	7	113	3	36257322
Pubmed	Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.	TRPC7 TRPC3 TRPC6	1.85e-06	8	113	3	25471572
Pubmed	Association of immunophilins with mammalian TRPC channels.	TRPC7 TRPC3 TRPC6	1.85e-06	8	113	3	15199065
Pubmed	Subunit composition of mammalian transient receptor potential channels in living cells.	TRPC7 TRPC3 TRPC6	1.85e-06	8	113	3	12032305
Pubmed	Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion.	TRPC7 TRPC3 TRPC6	2.77e-06	9	113	3	17480026
Pubmed	Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.	TRPC7 TRPC3 TRPC6	2.77e-06	9	113	3	11290752
Pubmed	The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.	TRPC7 TRPC3 TRPC6	3.94e-06	10	113	3	27177420
Pubmed	The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.	ATP9B ATP8B1 ATP8A1	3.94e-06	10	113	3	15919184
Pubmed	Functional analysis of the SRY-KRAB interaction in mouse sex determination.	ZNF493 ZNF43 ZNF99	3.94e-06	10	113	3	18588511
Pubmed	Heterogeneous distribution of TRPC proteins in the embryonic cortex.	TRPC7 TRPC3 TRPC6	3.94e-06	10	113	3	18989690
Pubmed	Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.	ZNF493 ZNF43 ZNF99	5.41e-06	11	113	3	15469996
Pubmed	ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.	ATP9B ATP8B1 ATP8A1	7.19e-06	12	113	3	21914794
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP9B ATP8B1 ATP8A1	9.33e-06	13	113	3	11015572
Pubmed	Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.	ZNF493 ZNF43 ZNF99	9.33e-06	13	113	3	19850934
Pubmed	Melanopsin signalling in mammalian iris and retina.	TRPC7 TRPC3 TRPC6	9.33e-06	13	113	3	22051675
Pubmed	TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.	TRPC3 TRPC6	1.05e-05	2	113	2	22724068
Pubmed	Molecular genetic analysis of the dilute-short ear (d-se) region of the mouse.	MYO5A BMP5	1.05e-05	2	113	2	3000867
Pubmed	Linkage of Short Ear and Density in the House Mouse.	MYO5A BMP5	1.05e-05	2	113	2	16587226
Pubmed	Modulation of Transient Receptor Potential Channels 3 and 6 Regulates Osteoclast Function with Impact on Trabecular Bone Loss.	TRPC3 TRPC6	1.05e-05	2	113	2	32140760
Pubmed	[Mechanism of cardiac hypertrophy via diacylglycerol-sensitive TRPC channels].	TRPC3 TRPC6	1.05e-05	2	113	2	20190513
Pubmed	A Cross-over between the Genes for Short-Ear and Density in the House Mouse.	MYO5A BMP5	1.05e-05	2	113	2	16587426
Pubmed	Copy number gain of PIK3CA and MET is associated with poor prognosis in head and neck squamous cell carcinoma.	MET PIK3CA	1.05e-05	2	113	2	26832731
Pubmed	In vivo expression of HGF/NK1 and GLP-1 From dsAAV vectors enhances pancreatic ß-cell proliferation and improves pathology in the db/db mouse model of diabetes.	LEPR MET	1.05e-05	2	113	2	20841608
Pubmed	Overexpression of PI3K p110α contributes to acquired resistance to MET inhibitor, in MET-amplified SNU-5 gastric xenografts.	MET PIK3CA	1.05e-05	2	113	2	26543351
Pubmed	Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.	TRPC7 TRPC6	1.05e-05	2	113	2	23529130
Pubmed	DHA induces Jurkat T-cell arrest in G2/M phase of cell cycle and modulates the plasma membrane expression of TRPC3/6 channels.	TRPC3 TRPC6	1.05e-05	2	113	2	33333171
Pubmed	N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.	TRPC3 TRPC6	1.05e-05	2	113	2	12970363
Pubmed	PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels.	TRPC7 TRPC6	1.05e-05	2	113	2	24470487
Pubmed	Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.	TRPC3 TRPC6	1.05e-05	2	113	2	9930701
Pubmed	Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.	TRPC3 TRPC6	1.05e-05	2	113	2	24453217
Pubmed	LepRb+ cell-specific deletion of Slug mitigates obesity and nonalcoholic fatty liver disease in mice.	LEPR SNAI2	1.05e-05	2	113	2	36512408
Pubmed	Upregulation and Diverse Roles of TRPC3 and TRPC6 in Synaptic Reorganization of the Mossy Fiber Pathway in Temporal Lobe Epilepsy.	TRPC3 TRPC6	1.05e-05	2	113	2	25213992
Pubmed	Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension.	TRPC3 TRPC6	1.05e-05	2	113	2	27861908
Pubmed	Structure of the receptor-activated human TRPC6 and TRPC3 ion channels.	TRPC3 TRPC6	1.05e-05	2	113	2	29700422
Pubmed	Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.	TRPC3 TRPC6	1.05e-05	2	113	2	23800468
Pubmed	TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes.	TRPC3 TRPC6	1.05e-05	2	113	2	28105583
Pubmed	Loss of heterozygosity at the dilute-short ear (Myo5a-Bmp5) region of the mouse: mitotic recombination or double non-disjunction?	MYO5A BMP5	1.05e-05	2	113	2	10036975
Pubmed	Serum NOX1 and Raftlin as new potential biomarkers of Major Depressive Disorder: A study in treatment-naive first episode patients.	RFTN1 NOX1	1.05e-05	2	113	2	36341844
Pubmed	Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.	TRPC3 TRPC6	1.05e-05	2	113	2	35051376
Pubmed	IDENTICAL TWINS IN A MOUSE CROSS.	MYO5A BMP5	1.05e-05	2	113	2	17748600
Pubmed	Diacylglycerol-containing oleic acid induces increases in [Ca(2+)](i) via TRPC3/6 channels in human T-cells.	TRPC3 TRPC6	1.05e-05	2	113	2	22306362
Pubmed	[Regulation of cardiac hypertrophy by the formation of G protein-coupled receptor--TRPC channel protein complex].	TRPC3 TRPC6	1.05e-05	2	113	2	19749484
Pubmed	Myosin Va controls oligodendrocyte morphogenesis and myelination.	MYO5A BMP5	1.05e-05	2	113	2	17942731
Pubmed	Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein.	TRPC3 TRPC6	1.05e-05	2	113	2	9368034
Pubmed	Leptin receptor signaling in the hypothalamus regulates hepatic autonomic nerve activity via phosphatidylinositol 3-kinase and AMP-activated protein kinase.	LEPR PIK3CA	1.05e-05	2	113	2	25589743
Pubmed	Linkage of the Factors for Short-Ear and Density in the House Mouse (MUS MUSCULUS).	MYO5A BMP5	1.05e-05	2	113	2	17246548
Pubmed	A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia.	TRPC3 TRPC6	1.05e-05	2	113	2	35805125
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF493 ZNF43 ZNF85 ZNF99	2.00e-05	49	113	4	9630514
Pubmed	Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.	TRPC7 TRPC3 TRPC6	2.20e-05	17	113	3	22411552
Pubmed	Calcium sensing receptor modulates extracellular calcium entry and proliferation via TRPC3/6 channels in cultured human mesangial cells.	TRPC3 TRPC6	3.13e-05	3	113	2	24905090
Pubmed	TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice.	TRPC3 TRPC6	3.13e-05	3	113	2	28790356
Pubmed	Genetic ablation of a mouse gene expressed specifically in brain.	MYO5A BMP5	3.13e-05	3	113	2	2303033
Pubmed	Selective association of TRPC channel subunits in rat brain synaptosomes.	TRPC3 TRPC6	3.13e-05	3	113	2	12377790
Pubmed	Involvement of phosphoinositide 3-kinase class IA (PI3K 110α) and NADPH oxidase 1 (NOX1) in regulation of vascular differentiation induced by vascular endothelial growth factor (VEGF) in mouse embryonic stem cells.	NOX1 PIK3CA	3.13e-05	3	113	2	26553657
Pubmed	Insulin-activated store-operated Ca2+ entry via Orai1 induces podocyte actin remodeling and causes proteinuria.	TRPC6 LEPR	3.13e-05	3	113	2	34764278
Pubmed	Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects.	LEPR PIK3CA	3.13e-05	3	113	2	23541372
Pubmed	Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells.	TRPC7 TRPC3	3.13e-05	3	113	2	15972814
Pubmed	Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.	TRPC3 TRPC6	3.13e-05	3	113	2	23938296
Pubmed	Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension.	TRPC3 TRPC6	3.13e-05	3	113	2	15358862
Pubmed	Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations.	MYO5A BMP5	3.13e-05	3	113	2	5556347
Pubmed	The transient receptor potential (TRP) channel TRPC3 TRP domain and AMP-activated protein kinase binding site are required for TRPC3 activation by erythropoietin.	TRPC3 TRPC6	3.13e-05	3	113	2	21757714
Pubmed	Orai proteins interact with TRPC channels and confer responsiveness to store depletion.	TRPC3 TRPC6	3.13e-05	3	113	2	17360584
Pubmed	A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.	TRPC7 TRPC3	3.13e-05	3	113	2	19812035
Pubmed	The Retinal Basis of Light Aversion in Neonatal Mice.	TRPC7 TRPC6	3.13e-05	3	113	2	35396331
Pubmed	TRPC3 activation by erythropoietin is modulated by TRPC6.	TRPC3 TRPC6	3.13e-05	3	113	2	19074769
Pubmed	Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist.	LEPR NOX1	3.13e-05	3	113	2	15922295
Pubmed	CPNE1 promotes non-small cell lung cancer progression by interacting with RACK1 via the MET signaling pathway.	MET CPNE1	3.13e-05	3	113	2	35101055
Pubmed	Apolipoprotein E knockout as the basis for mouse models of dyslipidemia-induced neuropathy.	APOB LEPR	3.13e-05	3	113	2	23059459
Pubmed	The Effect and Mechanism of TRPC1, 3, and 6 on the Proliferation, Migration, and Lumen Formation of Retinal Vascular Endothelial Cells Induced by High Glucose.	TRPC3 TRPC6	3.13e-05	3	113	2	32097940
Pubmed	Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho.	TRPC3 TRPC6	3.13e-05	3	113	2	27979597
Pubmed	Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice.	TRPC3 TRPC6	3.13e-05	3	113	2	36569761
Pubmed	Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry.	TRPC3 TRPC6	3.13e-05	3	113	2	10611319
Pubmed	Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes.	TRPC3 TRPC6	3.13e-05	3	113	2	19052171
Pubmed	MET in gastric cancer--discarding a 10% cutoff rule.	MET PIK3CA	3.13e-05	3	113	2	26033401
Pubmed	SOX13 promotes colorectal cancer metastasis by transactivating SNAI2 and c-MET.	MET SNAI2	3.13e-05	3	113	2	32111984
Pubmed	The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells.	MYO5A BMP5	3.13e-05	3	113	2	7493015
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	KIF18A MYO5A VEZT DSP RNF213 YWHAH RFTN1 PTPN14 PPP5C PTPRG CEBPZ CEP135 CPVL	3.76e-05	1049	113	13	27880917
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	ZSCAN5DP ZSCAN5A ZSCAN5C PADI6	3.91e-05	58	113	4	31598710
Pubmed	Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.	TRPC7 TRPC3 TRPC6	4.26e-05	21	113	3	30270038
Pubmed	Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.	YWHAH PTPN14 CPVL	5.64e-05	23	113	3	26933062
Pubmed	CAF-derived HGF promotes cell proliferation and drug resistance by up-regulating the c-Met/PI3K/Akt and GRP78 signalling in ovarian cancer cells.	MET PIK3CA	6.25e-05	4	113	2	28258248
Pubmed	Mechanism of action of aryl hydrocarbon receptor antagonists: inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression.	MYO5A BMP5	6.25e-05	4	113	2	1329656
Interaction	TRPC7 interactions	TRPC7 TRPC3 TRPC6	3.04e-06	6	109	3	int:TRPC7
Interaction	ANKRD36B interactions	CHD8 ZNF708 ZNF594 ZNF92 ZNF724	1.82e-05	60	109	5	int:ANKRD36B
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF93 ZNF486 ZNF493 ZNF708 ZNF43 ZNF724 ZNF737 ZNF85 ZNF99 ZNF738 ZNF730	1.36e-14	122	113	11	chr19p12
Cytoband	19p12	ZNF93 ZNF486 ZNF493 ZNF708 ZNF724 ZNF737 ZNF85 ZNF99 ZNF738 ZNF730	2.63e-14	90	113	10	19p12
Cytoband	4q27	ADAD1 NDNF TRPC3	2.16e-05	22	113	3	4q27
Cytoband	Ensembl 112 genes in cytogenetic band chr4q27	ADAD1 NDNF TRPC3	6.84e-05	32	113	3	chr4q27
Cytoband	9p24	SLC1A1 INSL6	1.67e-04	8	113	2	9p24
Cytoband	7q11.21	ZNF680 ZNF92 ZNF735	1.16e-03	83	113	3	7q11.21
Cytoband	19q13.43	ZSCAN5DP ZSCAN5A ZSCAN5C	1.32e-03	87	113	3	19q13.43
Cytoband	5p15.2	CMBL DNAH5	2.02e-03	27	113	2	5p15.2
Cytoband	Ensembl 112 genes in cytogenetic band chr9p24	SLC1A1 DMRT2 INSL6	2.27e-03	105	113	3	chr9p24
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF93 ZNF142 ZNF486 ZNF680 ZNF493 ZSCAN5DP FEZF2 ZNF366 ZSCAN5A ZBTB41 ZIM3 ZNF708 ZNF594 ZNF600 ZNF43 ZNF92 ZSCAN5C ZNF735 SNAI2 ZNF737 ZNF506 PLAG1 ZFHX3 ZNF85 ZNF99 ZNF730	4.85e-17	718	82	26	28
GeneFamily	ATPase phospholipid transporting	ATP9B ATP8B1 ATP8A1	3.93e-05	15	82	3	1210
GeneFamily	Transient receptor potential cation channels	TRPC7 TRPC3 TRPC6	2.71e-04	28	82	3	249
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	KIF18A GGNBP2 SLK ZNF486 MNS1 MYO5A SMCHD1 DOCK10 TAOK3 SMC3 CEBPZ ZNF43 PIK3CA ZNF85 EEA1	1.19e-07	656	111	15	M18979
Coexpression	DURAND_STROMA_NS_UP	CMBL ZNF493 DMRT2 PTPRG INSL6 ZNF43 ZNF85 ZNF99	1.79e-06	194	111	8	MM962
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DOCK4 SLK SMCHD1 KAT6A ATP8B1 STIL TRIP12 RFTN1 TAOK3 SMC3 NFATC3 CEP135 UTP20 ZFHX3 KLC1	3.34e-06	856	111	15	M4500
Coexpression	LAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM	CMBL KMT2B AK9 SLC1A1 SHROOM4 MET ZNF708 PTPRG CTNNA3 SHISA6	1.15e-05	417	111	10	M39224
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_1000	MNS1 MYO5A DOCK10 ZBTB41 TRIP12 LEPR ATP8A1 MEIOC PIK3CA SNAI2	2.96e-06	307	105	10	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k3
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	DOCK4 MYO5A ZNF366 SLC26A2 LEPR SHROOM4 PTPRG NFATC3 LRFN5 EEA1	4.41e-11	184	113	10	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NDNF SLC1A1 SHROOM4 MET ATP8A1 NFATC3 CTNNA3 ADGRF5	3.18e-08	191	113	8	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMCHD1 DOCK10 RNF213 ZNF708 RFTN1 ATP8A1 ZNF92	5.68e-07	190	113	7	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	NDNF SLC1A1 SHROOM4 MET ATP8A1 CTNNA3 ADGRF5	5.88e-07	191	113	7	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK4 TRPC3 TRPC6 DOCK10 BMP5 PTPRG PLEKHH2	6.53e-07	194	113	7	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	SMCHD1 KAT6A RNF213 APOB ATP8A1 DMRT2	6.67e-07	121	113	6	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8\|TCGA-Bladder / Sample_Type by Project: Shred V9	ZNF680 ZNF708 ZNF43 ZNF92 ZNF737 ZNF738	2.34e-06	150	113	6	1aa9320d97ff10994ea024751790524fe133aba9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MET PTPN14 ATP8A1 ADGRF5 DNAH5 SHISA6	3.28e-06	159	113	6	8680b054622f573a82b1625fb93c2d5db81d1034
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRPC6 MET PTPN14 DMRT2 CTNNA3 DNAH5	6.27e-06	178	113	6	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	COVID-19_Convalescent-PLT_1\|World / Disease Group and Platelet Clusters	ZNF142 NANP PNLDC1 NBPF11 TAOK3 PTPRG	6.48e-06	179	113	6	d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NDNF SLC1A1 SHROOM4 MET PTPN14 ATP8A1	6.48e-06	179	113	6	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NDNF TRPC6 ATP8B1 PTPN14 PLEKHH2 SHISA6	7.58e-06	184	113	6	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	ZNF366 ATP8B1 SLC1A1 LEPR SHROOM4 ADGRF5	8.31e-06	187	113	6	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TRPC3 TRPC6 RFTN1 BMP5 TAOK3 PLEKHH2	8.31e-06	187	113	6	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	DOCK4 SLC26A2 LEPR SHROOM4 PTPRG ADGRF5	9.10e-06	190	113	6	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP8B1 MET ATP8A1 CTNNA3 DNAH5 ANKRD30BL	9.38e-06	191	113	6	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	DOCK4 ATP8B1 SLC1A1 LEPR SHROOM4 ADGRF5	9.95e-06	193	113	6	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ZNF366 ATP8B1 LEPR PTPN14 ADGRF5	9.95e-06	193	113	6	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	DOCK4 ATP8B1 SLC1A1 LEPR SHROOM4 ADGRF5	9.95e-06	193	113	6	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NDNF SHROOM4 MET ATP8A1 CTNNA3 ADGRF5	9.95e-06	193	113	6	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RNF213 MET PTPN14 PLEKHH2 DNAH5 CPVL	1.02e-05	194	113	6	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	IPF-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	TRPC3 ATP8B1 SLC1A1 LEPR SHROOM4 PTPRG	1.02e-05	194	113	6	e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP MET ATP8A1 CTNNA3 DNAH5 ANKRD30BL	1.02e-05	194	113	6	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TRPC3 TRPC6 DOCK10 BMP5 SNAI2 PLEKHH2	1.02e-05	194	113	6	a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TRPC3 TRPC6 DOCK10 BMP5 PTPRG PLEKHH2	1.06e-05	195	113	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK4 NDNF ZNF366 SHROOM4 RFTN1 ADGRF5	1.06e-05	195	113	6	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	TCGA-Skin-Metastatic-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KAT6A SMC3 NFATC3 PIK3CA ZFHX3 ADGRF5	1.15e-05	198	113	6	af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCell	TCGA-Skin-Metastatic\|TCGA-Skin / Sample_Type by Project: Shred V9	KAT6A SMC3 NFATC3 PIK3CA ZFHX3 ADGRF5	1.15e-05	198	113	6	ad39cce004867f083f8da1954e0cf5a263815184
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KAT6A SMC3 NFATC3 PIK3CA ZFHX3 ADGRF5	1.15e-05	198	113	6	62cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	MNS1 SLC26A2 TRIP12 SMC3 EEA1 DNAH5	1.18e-05	199	113	6	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TRPC3 TRPC6 RFTN1 TAOK3 CTNNA3 ZFHX3	1.22e-05	200	113	6	d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TRPC3 TRPC6 RFTN1 SNAI2 CTNNA3 PLEKHH2	1.22e-05	200	113	6	cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NDNF TAOK3 ATP8A1 ADGRF5 DNAH5	4.73e-05	155	113	5	9cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRPC3 TRPC6 RFTN1 CTNNA3 ZFHX3	4.88e-05	156	113	5	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRPC6 PTPN14 DMRT2 CTNNA3 DNAH5	5.18e-05	158	113	5	d78e7e52657dc094430291fec07e9c298be9e584
ToppCell	COVID-19-APC-like-Monocytes\|COVID-19 / group, cell type (main and fine annotations)	ZNF93 ZNF366 ARRDC5 PIK3CA ZNF92	5.18e-05	158	113	5	a0d94bd067424783863a48db20976d4c2043600c
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SMCHD1 KAT6A DOCK10 ZNF708 ZNF506	5.84e-05	162	113	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	ZNF486 MET ATP8A1 PTPRG DNAH5	6.01e-05	163	113	5	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NDNF JADE3 DSP SLC1A1 CPVL	6.74e-05	167	113	5	bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NDNF JADE3 DSP SLC1A1 CPVL	6.74e-05	167	113	5	9f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 LEPR SHROOM4 NOX1 PTPRG	7.33e-05	170	113	5	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 LEPR SHROOM4 NOX1 PTPRG	7.33e-05	170	113	5	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRPC3 TRPC6 DOCK10 RFTN1 PLEKHH2	7.33e-05	170	113	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPC6 BMP5 PTPRG SNAI2 PLEKHH2	8.18e-05	174	113	5	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	ZNF486 MET ATP8A1 DNAH5 SHISA6	8.63e-05	176	113	5	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM4 MET ATP8A1 NFATC3 ADGRF5	9.85e-05	181	113	5	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC3 SLC1A1 PTPN14 PLEKHH2 CPVL	1.01e-04	182	113	5	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATP8B1 MET DNAH5 SHISA6 ANKRD30BL	1.01e-04	182	113	5	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLK SMCHD1 DOCK10 MET EEA1	1.01e-04	182	113	5	bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRPC3 TRPC6 RFTN1 CTNNA3 ZFHX3	1.04e-04	183	113	5	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	DSP SMCHD1 RNF213 CHD8 TRIP12	1.04e-04	183	113	5	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRPC3 TRPC6 RFTN1 CTNNA3 ZFHX3	1.06e-04	184	113	5	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRPC3 TRPC6 RFTN1 CTNNA3 PLEKHH2	1.06e-04	184	113	5	102b6f621a5b551e622f97b12d787c080b052a72
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF486 MET PTPN14 ATP8A1 DNAH5	1.06e-04	184	113	5	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRPC3 TRPC6 RFTN1 CTNNA3 ZFHX3	1.06e-04	184	113	5	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SMCHD1 STIL MET ZNF92 ZNF85	1.09e-04	185	113	5	3563dd39ec58d3273f95f5bb36b9ccdc0aafb63a
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRPC3 TRPC6 ATP8B1 RFTN1 DMRT2	1.09e-04	185	113	5	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	SMCHD1 DOCK10 RNF213 ZNF708 ATP8A1	1.09e-04	185	113	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NANP ZNF708 TARS3 SLC46A3 ZNF506	1.09e-04	185	113	5	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NANP ZNF708 TARS3 SLC46A3 ZNF506	1.09e-04	185	113	5	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MET ATP8A1 ADGRF5 DNAH5 ANKRD30BL	1.12e-04	186	113	5	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 PHAF1 ZNF600 PIK3CA PLEKHH2	1.12e-04	186	113	5	77bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC3 SLC1A1 PTPN14 PLEKHH2 CPVL	1.12e-04	186	113	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	SMCHD1 DOCK10 RNF213 ZNF708 ATP8A1	1.12e-04	186	113	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MET ATP8A1 PTPRG ADGRF5 ANKRD30BL	1.12e-04	186	113	5	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 PHAF1 ZNF600 PIK3CA PLEKHH2	1.12e-04	186	113	5	13bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRPC3 TRPC6 RFTN1 CTNNA3 ADGRF5	1.15e-04	187	113	5	fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DOCK4 TRPC6 BMP5 PTPRG PLEKHH2	1.15e-04	187	113	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	MET RFTN1 ATP8A1 PTPRG ADGRF5	1.15e-04	187	113	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Control-Endothelial_cells-Endothelial_cells_(general)\|Control / group, cell type (main and fine annotations)	ZNF366 LEPR SHROOM4 PTPRG ADGRF5	1.15e-04	187	113	5	fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP RNF213 MET DMRT2 ZNF737	1.15e-04	187	113	5	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF18A MNS1 STIL ZNF43 ZNF730	1.15e-04	187	113	5	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	LEPR BMP5 PTPRG LRFN5 PLEKHH2	1.15e-04	187	113	5	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	DSP TRPC6 MET PTPN14 DNAH5	1.15e-04	187	113	5	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	NDNF SLC1A1 MET ADGRF5 DNAH5	1.18e-04	188	113	5	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	DSP PTPN14 DMRT2 PTPRG ADGRF5	1.18e-04	188	113	5	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	SHROOM4 MET ATP8A1 PTPRG ADGRF5	1.21e-04	189	113	5	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF213 MET PTPN14 PTPRG DNAH5	1.21e-04	189	113	5	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP MET ATP8A1 CTNNA3 ANKRD30BL	1.21e-04	189	113	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	ATP8B1 SLC1A1 LEPR SHROOM4 ADGRF5	1.21e-04	189	113	5	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF213 MET PTPN14 PTPRG DNAH5	1.21e-04	189	113	5	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	JADE3 STIL ATP8A1 ZNF724 PLAG1	1.24e-04	190	113	5	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MET PTPN14 PLEKHH2 DNAH5 CPVL	1.24e-04	190	113	5	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	JADE3 STIL ATP8A1 ZNF724 PLAG1	1.24e-04	190	113	5	42312f7d79fe889397d32910b625793e2535cc26
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	DOCK4 NDNF DOCK10 BMP5 PLEKHH2	1.24e-04	190	113	5	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	JADE3 STIL ATP8A1 ZNF724 PLAG1	1.24e-04	190	113	5	682418a7a2096743112eae3790d40e7e600612c0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MET PTPN14 PLEKHH2 DNAH5 CPVL	1.27e-04	191	113	5	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	SMCHD1 DOCK10 RNF213 ZNF708 ATP8A1	1.27e-04	191	113	5	9454f642c3621370fa23640b631301346b300950
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZNF680 VPS50 TAOK3 SLC46A3 UTP20	1.27e-04	191	113	5	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRPC6 BMP5 PTPRG LRFN5 PLEKHH2	1.27e-04	191	113	5	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK4 ZNF366 ATP8B1 PTPRG ADGRF5	1.30e-04	192	113	5	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TRPC6 ATP8B1 RFTN1 CTNNA3 ADGRF5	1.30e-04	192	113	5	55f95454399fd533df75db06584eaa48d6ee3830
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	MET ATP8A1 PTPRG ADGRF5 DNAH5	1.30e-04	192	113	5	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NDNF PHAF1 TAOK3 ATP8A1 ADGRF5	1.33e-04	193	113	5	1fdfe08b0c82248545c29b504ac259b093fde29b
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF366 ATP8B1 LEPR SHROOM4 ADGRF5	1.33e-04	193	113	5	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF366 ATP8B1 LEPR SHROOM4 ADGRF5	1.33e-04	193	113	5	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZNF366 SLC26A2 ATP8B1 LEPR ADGRF5	1.33e-04	193	113	5	ad2df9b77999780860141be6ec366afc0172a331
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NDNF PHAF1 TAOK3 ATP8A1 ADGRF5	1.33e-04	193	113	5	5f90e3e526032d82d9dc7e0813fe79ca28dc0719
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	ZNF366 SLC1A1 SHROOM4 RFTN1 ADGRF5	1.33e-04	193	113	5	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TRPC3 TRPC6 BMP5 SNAI2 PLEKHH2	1.36e-04	194	113	5	28c5482da199bcee9e85258a88af453d9fdbd56a
Disease	nicotine dependence (implicated_via_orthology)	TRPC7 TRPC3 TRPC6	9.68e-06	12	106	3	DOID:0050742 (implicated_via_orthology)
Disease	hepatocellular carcinoma (is_implicated_in)	KMT2B LEPR MET SMC3 PIK3CA ZFHX3	5.03e-05	181	106	6	DOID:684 (is_implicated_in)
Disease	Neoplasm of the genitourinary tract	MET PIK3CA ZFHX3	8.63e-05	24	106	3	cv:C0042065
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	TDRD15 APOB	3.53e-04	8	106	2	EFO_0008589, EFO_0008595
Disease	HEPATOCELLULAR CARCINOMA	MET PIK3CA	4.53e-04	9	106	2	114550
Disease	Hepatocellular carcinoma	MET PIK3CA	4.53e-04	9	106	2	cv:C2239176
Disease	Muscular Dystrophy, Facioscapulohumeral	SMCHD1 FRG1	9.72e-04	13	106	2	C0238288
Disease	triglycerides in medium VLDL measurement	TDRD15 APOB CFAP97D1	1.03e-03	55	106	3	EFO_0022155
Disease	cholesteryl esters to total lipids in large VLDL percentage	TDRD15 APOB CFAP97D1	1.09e-03	56	106	3	EFO_0022250
Disease	Malformations of Cortical Development	SLC1A1 PIK3CA	1.13e-03	14	106	2	C1955869
Disease	Cortical Dysplasia	SLC1A1 PIK3CA	1.13e-03	14	106	2	C0431380
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	TDRD15 APOB	1.13e-03	14	106	2	EFO_0004611, EFO_0008589
Disease	phospholipids in VLDL measurement	TDRD15 APOB CFAP97D1	1.27e-03	59	106	3	EFO_0022301
Disease	free cholesterol to total lipids in very large VLDL percentage	TDRD15 APOB CFAP97D1	1.27e-03	59	106	3	EFO_0022289
Disease	low density lipoprotein triglyceride measurement	TDRD15 APOB	1.30e-03	15	106	2	EFO_0009946
Disease	Autosomal recessive primary microcephaly	STIL CEP135	1.30e-03	15	106	2	cv:C3711387
Disease	response to statin, LDL cholesterol change measurement	TDRD15 APOB	1.30e-03	15	106	2	EFO_0007804, GO_0036273
Disease	amenorrhea, response to antineoplastic agent	VPS50 APOB	1.30e-03	15	106	2	EFO_0010269, GO_0097327
Disease	total lipids in VLDL measurement	TDRD15 APOB CFAP97D1	1.33e-03	60	106	3	EFO_0022314
Disease	language measurement	DOCK10 RFTN1 PTPRG CTNNA3	1.41e-03	134	106	4	EFO_0007797
Disease	gout, hyperuricemia	ZNF724 ZNF730	1.48e-03	16	106	2	EFO_0004274, EFO_0009104
Disease	cholesterol in very large VLDL measurement	TDRD15 APOB CFAP97D1	1.67e-03	65	106	3	EFO_0022230
Disease	Benign neoplasm of stomach	MET PIK3CA	1.68e-03	17	106	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	MET PIK3CA	1.68e-03	17	106	2	C0496905
Disease	Lipidemias	APOB LEPR	1.68e-03	17	106	2	C1706412
Disease	Carcinoma in situ of stomach	MET PIK3CA	1.68e-03	17	106	2	C0154060
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	TDRD15 APOB	1.68e-03	17	106	2	EFO_0022232
Disease	Hyperlipidemia	APOB LEPR	1.68e-03	17	106	2	C0020473
Disease	total lipids in small VLDL	TDRD15 APOB CFAP97D1	1.83e-03	67	106	3	EFO_0022148
Disease	total lipids in large VLDL	TDRD15 APOB CFAP97D1	1.83e-03	67	106	3	EFO_0022175
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	TDRD15 APOB	1.88e-03	18	106	2	EFO_0008317, EFO_0008589
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	TDRD15 APOB ZFHX3	1.99e-03	69	106	3	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	sleep duration	ZNF486 TRPC7 TRPC6 KAT6A DMRT2 SHISA6	1.99e-03	362	106	6	EFO_0005271
Disease	peripheral neuropathy, response to docetaxel trihydrate	TRPC7 CTNNA3	2.10e-03	19	106	2	EFO_0003100, GO_1902519
Disease	DiGeorge syndrome (implicated_via_orthology)	ZNF366 KAT6A	2.10e-03	19	106	2	DOID:11198 (implicated_via_orthology)
Disease	psychotic symptoms	NANP CATSPERD SLC1A1	2.43e-03	74	106	3	EFO_0005940
Disease	Stomach Carcinoma	MET PIK3CA	2.57e-03	21	106	2	C0699791
Disease	Autosomal Recessive Primary Microcephaly	STIL CEP135	2.82e-03	22	106	2	C3711387
Disease	Primary microcephaly	STIL CEP135	2.82e-03	22	106	2	C0431350
Disease	proprotein convertase subtilisin/kexin type 9 measurement	TDRD15 APOB	2.82e-03	22	106	2	EFO_0009312
Disease	Kidney Failure	TRPC6 LEPR	2.82e-03	22	106	2	C0035078
Disease	tobacco smoke exposure measurement	AMIGO1 KLC1	3.35e-03	24	106	2	EFO_0009115
Disease	Dyslipidemias	APOB LEPR	3.35e-03	24	106	2	C0242339
Disease	Dyslipoproteinemias	APOB LEPR	3.35e-03	24	106	2	C0598784

Protein segments in the cluster

Peptide	Gene	Start	Entry
EKQFKLVTQCNAKYV	PTPRG	1151	P23470
KVLKCHQENSKNSYT	EDDM3B	101	P56851
LYCMNSKKLHNVFNL	AMIGO1	251	Q86WK6
FQDESYKKHLKHQCN	CHD8	1561	Q9HCK8
NTKYKLDIFLKQQQH	CATSPERD	451	Q86XM0
KFLIKNCNDFQYESK	YWHAH	106	Q04917
QEAKCKLKSYLQQHG	ADAD1	546	Q96M93
KNVFKKNHVNLYRSE	ATP8A1	1111	Q9Y2Q0
NTKFLCIKESKYANN	ATP8B1	81	O43520
TLFNKPKSHQKCRQY	RFTN1	281	Q14699
RYKVCNNNGQHKVTK	LRFN5	551	Q96NI6
FQCADHNLKTKKIYF	NOX1	421	Q9Y5S8
KKQNEYVEKCIHLNR	PADI6	556	Q6TGC4
RQHLKEKFNKYCRLN	GGNBP2	666	Q9H3C7
ELKSFYQQQCHKQIE	KIF18A	451	Q8NI77
ICNNKADYVHKTKTF	ARRDC5	81	A6NEK1
CEEKHPRNSIKNQKY	ATP9B	126	O43861
EKQKKYFQKQCHECI	CPVL	261	Q9H3G5
AEYHQSILAKQQKKF	PDCD6IP	256	Q8WUM4
KVQVKLSKECFHPYN	NANP	51	Q8TBE9
EKVLCKYFHSQNLQK	NDNF	511	Q8TB73
SNVSFHCIYKKENKI	LEPR	346	P48357
YCIFQDDKKVFCQKH	KMT2B	1671	Q9UMN6
CKVNQTLKQVIEKFY	PLEKHH2	1286	Q8IVE3
NNDKQKYTLKINHDC	PIK3CA	201	P42336
ECLYHQNDKQISIKK	KAT6A	701	Q92794
DLKFLNNQYAHKLKL	CEP135	116	Q66GS9
QIKFYSHQLKICSQV	CTNNA3	771	Q9UI47
NVKQCEINYVKKFQS	FRG1	201	Q14331
TKYQHLKAEFKQLQQ	EEA1	386	Q15075
CKEQHLFLPFSYKNK	APOB	261	P04114
HLKYDSQKCFNKARN	DOCK10	681	Q96BY6
YVHLKNACVKNKGQF	DOCK4	61	Q8N1I0
KKHRECLVKDNQKYT	DMRT2	501	Q9Y5R5
NLQKYQAECSQFKAK	DSP	1061	P15924
YENKQLCQKIANAHR	CFAP97D1	76	B2RV13
TSEQKQACKKHELYV	BMP5	346	P22003
QKLLKFLNKHYNLET	ATAT1	161	Q5SQI0
QACFQQYKTKREEVK	SLC1A1	156	P43005
VKFKSYCLKHSQNRQ	JADE3	356	Q92613
KLYQHEINLFKSKTN	CEBPZ	211	Q03701
FECIHPEKQQKKKSY	CPNE1	241	Q99829
EYQLCFHKTKQKLKQ	DNAH5	441	Q8TE73
EKQYKCTICNKAFHQ	FEZF2	386	Q8TBJ5
NLASCYLKQGKFKQA	KLC1	386	Q07866
KIVNKNNVRCLQHFY	MET	376	P08581
NYCKKLHVQALKNVN	MNS1	21	Q8NEH6
YNKFKCRILNEKVNT	TARS3	311	A2RTX5
NRIYICENKEKLQKF	AK9	1756	Q5TCS8
YVHPNKAKLNKCSNF	MEIOC	331	A2RUB1
KFYKEVIDKCQSFNQ	UTP20	66	O75691
QCNTELKKYSHVNKK	SMC3	971	Q9UQE7
CHEKYDKQIKFTLFK	SMCHD1	566	A6NHR9
CKQTLDALNYLHDNK	SLK	136	Q9H2G2
NKTVYCEFLKKHDQK	TDRD15	1436	B5MCY1
TQVACFLAKQQNKYK	NBPF8	281	Q3BBV2
TQVACFLAKQQNKYK	NBPF11	316	Q86T75
NINVYIHENAKFQKK	INSL6	136	Q9Y581
YQECNKIVKQKAFER	PPP5C	136	P53041
QKKLHRKCAYQILVQ	PPP5C	201	P53041
QQVYHKFQNLCKFDV	PNLDC1	436	Q8NA58
ATRHKFYKQNKICTE	PTPN14	296	Q15678
CFAYIVDQCKEHKQK	SLC46A3	151	Q7Z3Q1
HLQTHSDVKKYQCKN	SNAI2	231	O43623
ANLKAVCKSNEFEKY	SHROOM4	1351	Q9ULL8
KKRHEKLDQRQCTNY	SHISA6	131	Q6ZSJ9
TCKVQTKQYKALKNH	TAOK3	726	Q9H2K8
FYRQFCVKLAKKNQE	MROH2B	1486	Q7Z745
KVKLKYCGVHFNSQA	PHAF1	86	Q9BSU1
DKFKCVHQQLLEYKQ	ANKRD30BL	201	A7E2S9
AAKEVNKKQVCYKHN	ADGRF5	611	Q8IZF2
NKKQVCYKHNFNASS	ADGRF5	616	Q8IZF2
YQDCTFFNKKDILKL	CIB2	16	O75838
SAILKYLKQQCHAQK	CMBL	111	Q96DG6
KCLFNHFLKIDNQKF	C12orf29	301	Q8N999
NHCVKTFQEKTQRYK	C10orf82	36	Q8WW14
QQDCTKAFVSKYKLQ	PLAG1	66	Q6DJT9
YKHQQKKGEYVNRCL	RNF213	466	Q63HN8
LSKICKNFDINHYTK	VPS50	241	Q96JG6
DTKFQKLQYKDLCTH	VPS50	301	Q96JG6
YRHAKQNKKNSSCFL	STIL	66	Q15468
QSKVFQCDKYGKVFH	ZNF93	141	P35789
QGKIFQCNKYVKVFH	ZNF99	141	A8MXY4
CINHEKIHNAKKSYQ	ZIM3	266	Q96PE6
FQCDKYVKVFHKFLN	ZNF738	176	Q8NE65
IHLCNNAVQKYLKND	TTLL8	446	A6PVC2
QCDKYVKVFHKFPNV	ZNF92	146	Q03936
NQHQIIHTKEKSYKC	ZNF735	201	P0CB33
QSKIFQCDKYVKDFH	ZNF724	141	A8MTY0
QCDKYVKDFHKFSNS	ZNF724	146	A8MTY0
CNQVFTYRKNLNEHK	ZSCAN5DP	441	P0CG00
FCVIKKDHQSRNLKY	SLC35A5	71	Q9BS91
NKECFKSALYKQTVN	SLC26A2	591	P50443
QKYKATFHQCDVCKK	ZBTB41	661	Q5SVQ8
VCQKQFTQKSYLKCH	ZSCAN5A	416	Q9BUG6
VQVHFYLCNGKRKKS	NFATC3	676	Q12968
QCDKYVKVFHKFSNS	ZNF730	146	Q6ZMV8
FQKATLRRYKNCEHK	ZNF43	96	P17038
QSKIVQCDKYVKVFH	ZNF708	136	P17019
LCYKSFVQKQTLKAH	ZNF366	481	Q8N895
FQCDKYVKVFHKLLN	ZNF493	26	Q6ZR52
EHQKIHNINKTYECK	ZNF594	116	Q96JF6
FQCDKYVKVAHKFSN	ZNF85	146	Q03923
LKHCKTVLKQEKNNY	TTC37	26	Q6PGP7
CNYKAKQKFQVVKHV	ZNF142	1626	P52746
KYEVKKFVAHPNCQQ	TRPC6	371	Q9Y210
IFFSQCNKKDDLLHK	VEZT	71	Q9HBM0
QALKFFNTHQLKCQL	TRIP12	1256	Q14669
KCDVCGKLFNHKQYL	ZNF600	191	Q6ZNG1
SKIFQCGKYVKVFHQ	ZNF486	151	Q96H40
KYLIAACQHLQKKNY	ZFYVE26	2236	Q68DK2
CDKYVKVFHKFSNSN	ZNF680	156	Q8NEM1
ICQKQFTQKSYLKCH	ZSCAN5C	416	A6NGD5
KAYKQSCNLTTHKII	ZNF506	236	Q5JVG8
IKYEVKKFVAHPNCQ	TRPC3	301	Q13507
KYEVKKFVAHPNCQQ	TRPC7	316	Q9HCX4
NQHQIIHTKEKSYKC	ZNF722	201	A0A1W2PQL4
YNTQLKANFQLHCKT	ZFHX3	991	Q15911
QSKIFQCDKYVKVIH	ZNF737	141	O75373
QCDKYVKVIHKFSNS	ZNF737	146	O75373
KLYNTHLNKCALFEK	MYO5A	526	Q9Y4I1