| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | unmethylated CpG binding | 8.73e-08 | 10 | 19 | 3 | GO:0045322 | |
| GeneOntologyMolecularFunction | histone H3K4 monomethyltransferase activity | 2.39e-05 | 8 | 19 | 2 | GO:0140945 | |
| GeneOntologyMolecularFunction | histone H3K4 trimethyltransferase activity | 3.84e-05 | 10 | 19 | 2 | GO:0140999 | |
| GeneOntologyMolecularFunction | histone H3K4 methyltransferase activity | 1.61e-04 | 20 | 19 | 2 | GO:0042800 | |
| GeneOntologyMolecularFunction | histone H3 methyltransferase activity | 7.92e-04 | 44 | 19 | 2 | GO:0140938 | |
| GeneOntologyMolecularFunction | protein-lysine N-methyltransferase activity | 1.88e-03 | 68 | 19 | 2 | GO:0016279 | |
| GeneOntologyMolecularFunction | histone binding | 1.91e-03 | 265 | 19 | 3 | GO:0042393 | |
| GeneOntologyMolecularFunction | lysine N-methyltransferase activity | 1.94e-03 | 69 | 19 | 2 | GO:0016278 | |
| GeneOntologyMolecularFunction | histone methyltransferase activity | 2.05e-03 | 71 | 19 | 2 | GO:0042054 | |
| GeneOntologyMolecularFunction | protein methyltransferase activity | 4.26e-03 | 103 | 19 | 2 | GO:0008276 | |
| GeneOntologyMolecularFunction | N-methyltransferase activity | 4.42e-03 | 105 | 19 | 2 | GO:0008170 | |
| GeneOntologyCellularComponent | histone methyltransferase complex | 4.12e-05 | 75 | 19 | 3 | GO:0035097 | |
| GeneOntologyCellularComponent | methyltransferase complex | 1.22e-04 | 108 | 19 | 3 | GO:0034708 | |
| GeneOntologyCellularComponent | MLL1/2 complex | 4.06e-04 | 33 | 19 | 2 | GO:0044665 | |
| Domain | zf-CXXC | 1.23e-07 | 11 | 18 | 3 | PF02008 | |
| Domain | ZF_CXXC | 1.23e-07 | 11 | 18 | 3 | PS51058 | |
| Domain | Znf_CXXC | 1.23e-07 | 11 | 18 | 3 | IPR002857 | |
| Domain | MeTrfase_trithorax | 8.77e-07 | 2 | 18 | 2 | IPR016569 | |
| Domain | FYrich_C | 8.76e-06 | 5 | 18 | 2 | IPR003889 | |
| Domain | FYrich_N | 8.76e-06 | 5 | 18 | 2 | IPR003888 | |
| Domain | FYRC | 8.76e-06 | 5 | 18 | 2 | SM00542 | |
| Domain | FYRN | 8.76e-06 | 5 | 18 | 2 | SM00541 | |
| Domain | FYRN | 8.76e-06 | 5 | 18 | 2 | PF05964 | |
| Domain | FYRC | 8.76e-06 | 5 | 18 | 2 | PF05965 | |
| Domain | FYRC | 8.76e-06 | 5 | 18 | 2 | PS51543 | |
| Domain | FYRN | 8.76e-06 | 5 | 18 | 2 | PS51542 | |
| Domain | PHD | 4.86e-05 | 75 | 18 | 3 | PF00628 | |
| Domain | Znf_PHD-finger | 5.68e-05 | 79 | 18 | 3 | IPR019787 | |
| Domain | PHD | 8.10e-05 | 89 | 18 | 3 | SM00249 | |
| Domain | Znf_PHD | 8.66e-05 | 91 | 18 | 3 | IPR001965 | |
| Domain | ZF_PHD_2 | 9.84e-05 | 95 | 18 | 3 | PS50016 | |
| Domain | ZF_PHD_1 | 1.02e-04 | 96 | 18 | 3 | PS01359 | |
| Domain | PostSET | 1.04e-04 | 16 | 18 | 2 | SM00508 | |
| Domain | Post-SET_dom | 1.04e-04 | 16 | 18 | 2 | IPR003616 | |
| Domain | POST_SET | 1.04e-04 | 16 | 18 | 2 | PS50868 | |
| Domain | EPHD | 2.00e-04 | 22 | 18 | 2 | PS51805 | |
| Domain | AT_hook | 3.04e-04 | 27 | 18 | 2 | SM00384 | |
| Domain | AT_hook_DNA-bd_motif | 3.04e-04 | 27 | 18 | 2 | IPR017956 | |
| Domain | Znf_FYVE_PHD | 3.57e-04 | 147 | 18 | 3 | IPR011011 | |
| Domain | SET | 7.04e-04 | 41 | 18 | 2 | PF00856 | |
| Domain | SET | 8.85e-04 | 46 | 18 | 2 | SM00317 | |
| Domain | SET_dom | 1.05e-03 | 50 | 18 | 2 | IPR001214 | |
| Domain | SET | 1.05e-03 | 50 | 18 | 2 | PS50280 | |
| Domain | PH | 2.26e-03 | 278 | 18 | 3 | SM00233 | |
| Domain | PH_DOMAIN | 2.28e-03 | 279 | 18 | 3 | PS50003 | |
| Domain | PH_domain | 2.30e-03 | 280 | 18 | 3 | IPR001849 | |
| Domain | - | 3.53e-03 | 679 | 18 | 4 | 3.30.160.60 | |
| Domain | zf-C2H2 | 3.79e-03 | 693 | 18 | 4 | PF00096 | |
| Domain | Znf_C2H2/integrase_DNA-bd | 3.81e-03 | 694 | 18 | 4 | IPR013087 | |
| Domain | ZINC_FINGER_C2H2_2 | 5.65e-03 | 775 | 18 | 4 | PS50157 | |
| Domain | ZINC_FINGER_C2H2_1 | 5.70e-03 | 777 | 18 | 4 | PS00028 | |
| Domain | Znf_C2H2-like | 6.21e-03 | 796 | 18 | 4 | IPR015880 | |
| Domain | Znf_C2H2 | 6.46e-03 | 805 | 18 | 4 | IPR007087 | |
| Domain | ZnF_C2H2 | 6.55e-03 | 808 | 18 | 4 | SM00355 | |
| Domain | PH_dom-like | 7.45e-03 | 426 | 18 | 3 | IPR011993 | |
| Domain | - | 8.61e-03 | 449 | 18 | 3 | 3.30.40.10 | |
| Domain | Znf_RING/FYVE/PHD | 9.14e-03 | 459 | 18 | 3 | IPR013083 | |
| Domain | Ank_2 | 1.79e-02 | 215 | 18 | 2 | PF12796 | |
| Pathway | REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES | 6.44e-06 | 38 | 14 | 3 | MM17073 | |
| Pathway | REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES | 8.75e-06 | 42 | 14 | 3 | M48018 | |
| Pathway | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | 2.71e-04 | 25 | 14 | 2 | MM14511 | |
| Pathway | REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION | 2.96e-04 | 136 | 14 | 3 | MM14848 | |
| Pathway | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | 3.17e-04 | 27 | 14 | 2 | M12123 | |
| Pathway | REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION | 8.46e-04 | 44 | 14 | 2 | MM15527 | |
| Pathway | REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES | 9.25e-04 | 46 | 14 | 2 | MM14933 | |
| Pathway | REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION | 1.82e-03 | 254 | 14 | 3 | M27131 | |
| Pathway | WP_HISTONE_MODIFICATIONS | 1.84e-03 | 65 | 14 | 2 | M39374 | |
| Pathway | REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES | 2.13e-03 | 70 | 14 | 2 | M27231 | |
| Pathway | REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION | 3.96e-03 | 96 | 14 | 2 | M27792 | |
| Pubmed | 3.03e-08 | 12 | 19 | 3 | 27563068 | ||
| Pubmed | 7.71e-08 | 16 | 19 | 3 | 23870121 | ||
| Pubmed | Structural basis for activity regulation of MLL family methyltransferases. | 2.11e-07 | 22 | 19 | 3 | 26886794 | |
| Pubmed | KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions. | 2.83e-07 | 2 | 19 | 2 | 28723559 | |
| Pubmed | A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. | 2.83e-07 | 2 | 19 | 2 | 30503706 | |
| Pubmed | 1.68e-06 | 43 | 19 | 3 | 33472061 | ||
| Pubmed | WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket. | 1.70e-06 | 4 | 19 | 2 | 18840606 | |
| Pubmed | MLL1 is required for PAX7 expression and satellite cell self-renewal in mice. | 1.70e-06 | 4 | 19 | 2 | 31534153 | |
| Pubmed | A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity. | 1.70e-06 | 4 | 19 | 2 | 23129768 | |
| Pubmed | 1.70e-06 | 4 | 19 | 2 | 17166833 | ||
| Pubmed | 1.70e-06 | 4 | 19 | 2 | 26267306 | ||
| Pubmed | 1.70e-06 | 4 | 19 | 2 | 25834037 | ||
| Pubmed | Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA. | 1.70e-06 | 4 | 19 | 2 | 34156981 | |
| Pubmed | 2.67e-06 | 50 | 19 | 3 | 37974198 | ||
| Pubmed | 2.82e-06 | 5 | 19 | 2 | 26320581 | ||
| Pubmed | 2.82e-06 | 5 | 19 | 2 | 25561738 | ||
| Pubmed | MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia. | 2.82e-06 | 5 | 19 | 2 | 28609655 | |
| Pubmed | MLL associates specifically with a subset of transcriptionally active target genes. | 4.24e-06 | 6 | 19 | 2 | 16199523 | |
| Pubmed | Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs. | 4.24e-06 | 6 | 19 | 2 | 24176642 | |
| Pubmed | 4.88e-06 | 61 | 19 | 3 | 20305087 | ||
| Pubmed | Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases. | 7.90e-06 | 8 | 19 | 2 | 23130995 | |
| Pubmed | 7.90e-06 | 8 | 19 | 2 | 22266653 | ||
| Pubmed | Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression. | 1.02e-05 | 9 | 19 | 2 | 16951254 | |
| Pubmed | 1.02e-05 | 9 | 19 | 2 | 22665483 | ||
| Pubmed | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. | 1.27e-05 | 10 | 19 | 2 | 29276034 | |
| Pubmed | Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS. | 1.27e-05 | 10 | 19 | 2 | 18838538 | |
| Pubmed | Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression. | 1.55e-05 | 11 | 19 | 2 | 18082152 | |
| Pubmed | 2.20e-05 | 13 | 19 | 2 | 24619213 | ||
| Pubmed | 3.64e-05 | 119 | 19 | 3 | 23508102 | ||
| Pubmed | Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition. | 5.90e-05 | 21 | 19 | 2 | 27626377 | |
| Pubmed | 8.42e-05 | 25 | 19 | 2 | 25664857 | ||
| Pubmed | Rebalancing gene haploinsufficiency in vivo by targeting chromatin. | 1.06e-04 | 28 | 19 | 2 | 27256596 | |
| Pubmed | Identification and characterization of a novel human PP1 phosphatase complex. | 1.30e-04 | 31 | 19 | 2 | 20516061 | |
| Pubmed | Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation. | 1.90e-04 | 208 | 19 | 3 | 33230847 | |
| Pubmed | 2.64e-04 | 44 | 19 | 2 | 24183668 | ||
| Pubmed | 3.27e-04 | 49 | 19 | 2 | 34368113 | ||
| Pubmed | 3.30e-04 | 251 | 19 | 3 | 31076518 | ||
| Pubmed | 4.43e-04 | 57 | 19 | 2 | 18022353 | ||
| Pubmed | The LMO2 oncogene regulates DNA replication in hematopoietic cells. | 4.59e-04 | 58 | 19 | 2 | 26764384 | |
| Pubmed | Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci. | 5.08e-04 | 61 | 19 | 2 | 8662221 | |
| Interaction | KANSL2 interactions | 4.97e-07 | 70 | 19 | 4 | int:KANSL2 | |
| Interaction | KAT14 interactions | 3.29e-06 | 112 | 19 | 4 | int:KAT14 | |
| Interaction | PHF20 interactions | 1.62e-05 | 53 | 19 | 3 | int:PHF20 | |
| Interaction | ATN1 interactions | 2.50e-05 | 187 | 19 | 4 | int:ATN1 | |
| Interaction | SETD1B interactions | 4.60e-05 | 75 | 19 | 3 | int:SETD1B | |
| Interaction | PHF20L1 interactions | 4.60e-05 | 75 | 19 | 3 | int:PHF20L1 | |
| Interaction | BUB3 interactions | 5.79e-05 | 232 | 19 | 4 | int:BUB3 | |
| Interaction | MCRS1 interactions | 6.09e-05 | 235 | 19 | 4 | int:MCRS1 | |
| Interaction | KANSL3 interactions | 6.92e-05 | 86 | 19 | 3 | int:KANSL3 | |
| Interaction | HCFC2 interactions | 8.46e-05 | 92 | 19 | 3 | int:HCFC2 | |
| Interaction | RERE interactions | 8.74e-05 | 93 | 19 | 3 | int:RERE | |
| Interaction | ZNF608 interactions | 8.74e-05 | 93 | 19 | 3 | int:ZNF608 | |
| Interaction | KAT8 interactions | 9.31e-05 | 95 | 19 | 3 | int:KAT8 | |
| Interaction | KANSL1 interactions | 9.60e-05 | 96 | 19 | 3 | int:KANSL1 | |
| Interaction | ELF1 interactions | 2.15e-04 | 126 | 19 | 3 | int:ELF1 | |
| Interaction | KMT2B interactions | 2.36e-04 | 130 | 19 | 3 | int:KMT2B | |
| Interaction | CXXC1 interactions | 2.46e-04 | 132 | 19 | 3 | int:CXXC1 | |
| Interaction | MYB interactions | 2.52e-04 | 133 | 19 | 3 | int:MYB | |
| Interaction | KMT2C interactions | 2.58e-04 | 134 | 19 | 3 | int:KMT2C | |
| Interaction | ZZZ3 interactions | 2.87e-04 | 139 | 19 | 3 | int:ZZZ3 | |
| Interaction | TADA3 interactions | 2.99e-04 | 141 | 19 | 3 | int:TADA3 | |
| Interaction | NCOA6 interactions | 3.25e-04 | 145 | 19 | 3 | int:NCOA6 | |
| Interaction | BOD1L1 interactions | 3.52e-04 | 149 | 19 | 3 | int:BOD1L1 | |
| Interaction | ELF2 interactions | 4.02e-04 | 156 | 19 | 3 | int:ELF2 | |
| Interaction | H3C14 interactions | 4.02e-04 | 156 | 19 | 3 | int:H3C14 | |
| Interaction | KDM6A interactions | 4.49e-04 | 162 | 19 | 3 | int:KDM6A | |
| Interaction | MBIP interactions | 4.74e-04 | 165 | 19 | 3 | int:MBIP | |
| Interaction | YEATS2 interactions | 5.09e-04 | 169 | 19 | 3 | int:YEATS2 | |
| Interaction | KMT2D interactions | 5.09e-04 | 169 | 19 | 3 | int:KMT2D | |
| Interaction | SETD1A interactions | 5.17e-04 | 170 | 19 | 3 | int:SETD1A | |
| Interaction | FEV interactions | 8.66e-04 | 203 | 19 | 3 | int:FEV | |
| Interaction | DPY30 interactions | 8.79e-04 | 204 | 19 | 3 | int:DPY30 | |
| Interaction | WDR82 interactions | 9.96e-04 | 213 | 19 | 3 | int:WDR82 | |
| Interaction | NFIX interactions | 1.20e-03 | 227 | 19 | 3 | int:NFIX | |
| Interaction | ELP4 interactions | 1.54e-03 | 62 | 19 | 2 | int:ELP4 | |
| Cytoband | 3q29 | 5.41e-04 | 83 | 19 | 2 | 3q29 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr3q29 | 1.46e-03 | 137 | 19 | 2 | chr3q29 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr12q21 | 1.55e-03 | 141 | 19 | 2 | chr12q21 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q23 | 3.70e-03 | 220 | 19 | 2 | chr11q23 | |
| GeneFamily | Zinc fingers CXXC-type | 6.36e-08 | 12 | 13 | 3 | 136 | |
| GeneFamily | PHD finger proteins | 3.29e-05 | 90 | 13 | 3 | 88 | |
| GeneFamily | Zinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family | 2.64e-04 | 34 | 13 | 2 | 487 | |
| GeneFamily | Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes | 1.32e-03 | 718 | 13 | 4 | 28 | |
| Disease | joint damage measurement | 8.72e-04 | 68 | 19 | 2 | EFO_0005413 | |
| Disease | congenital heart disease (implicated_via_orthology) | 8.98e-04 | 69 | 19 | 2 | DOID:1682 (implicated_via_orthology) | |
| Disease | Dystonia | 1.39e-03 | 86 | 19 | 2 | C0013421 | |
| Disease | apolipoprotein A 1 measurement | 1.86e-03 | 848 | 19 | 4 | EFO_0004614 | |
| Disease | insomnia measurement | 2.72e-03 | 443 | 19 | 3 | EFO_0007876 | |
| Disease | adiponectin measurement | 3.93e-03 | 146 | 19 | 2 | EFO_0004502 | |
| Disease | Malignant neoplasm of breast | 4.37e-03 | 1074 | 19 | 4 | C0006142 | |
| Disease | prostate cancer (is_marker_for) | 4.48e-03 | 156 | 19 | 2 | DOID:10283 (is_marker_for) | |
| Disease | sexual dimorphism measurement | 4.85e-03 | 1106 | 19 | 4 | EFO_0021796 | |
| Disease | autoimmune disease | 5.47e-03 | 173 | 19 | 2 | EFO_0005140 | |
| Disease | calcium measurement | 7.21e-03 | 628 | 19 | 3 | EFO_0004838 | |
| Disease | metabolic syndrome | 7.25e-03 | 200 | 19 | 2 | EFO_0000195 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| DLCEFFCKHCRERPR | 241 | Q8IY22 | |
| CTVKHCEDIERRFCF | 316 | Q15057 | |
| TVHDDCRRRFSKECC | 436 | Q5KSL6 | |
| CCDPFHPFCLEEAER | 1221 | Q9UMN6 | |
| EDCHFLAAICPDCFK | 221 | Q3MIT2 | |
| RRTEDCGHCDFCRDM | 176 | Q9P0U4 | |
| EEVQCDGRSFHRCCF | 21 | Q16527 | |
| SDEFFCRCHRPYCEI | 751 | Q8NFN8 | |
| CCEPFHKFCLEENER | 1451 | Q03164 | |
| FRHSEDRPFKCDCCD | 276 | Q9BQA5 | |
| IFPFELHKCRTCEEC | 901 | Q92622 | |
| RLFCDICDCFDLHDT | 1376 | P30622 | |
| CTDKCDDSFVHRDCI | 386 | Q3ZCN5 | |
| CDRFEFECHQPKTCI | 1471 | Q92673 | |
| EKPHKCELCDFTCRD | 426 | P52746 | |
| NGFFECERRCDADPC | 1991 | P01266 | |
| VHCKDRPFKCDFCSF | 516 | Q9NTW7 | |
| ERPHDYFCKCNECTE | 191 | Q9HCX4 | |
| PFECEECGKAFRHRS | 326 | Q49AA0 |