Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C STXBP5L TBC1D3B TBC1D3K TBC1D3F

2.41e-132794112GO:0005096
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C STXBP5L TBC1D3B TBC1D3K TBC1D3F

2.55e-105074112GO:0030695
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C STXBP5L TBC1D3B TBC1D3K TBC1D3F

2.55e-105074112GO:0060589
GeneOntologyMolecularFunctionenzyme activator activity

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G GPR158 TBC1D3C STXBP5L TBC1D3B TBC1D3K TBC1D3F

3.49e-106564113GO:0008047
GeneOntologyMolecularFunctionenzyme regulator activity

CDKN2A TBC1D3E IRS1 TBC1D3 TBC1D3L TBC1D3H BSN TBC1D3I TBC1D3D TBC1D3G GPR158 TBC1D3C STXBP5L TBC1D3B TBC1D3K TBC1D3F

7.23e-0914184116GO:0030234
GeneOntologyMolecularFunctionmolecular function activator activity

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G GPR158 TBC1D3C STXBP5L TBC1D3B TBC1D3K TBC1D3F

6.17e-0712334113GO:0140677
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1 KAT6A

2.50e-06303417GO:0003713
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

ARID1A ATRX CECR2

5.95e-0537413GO:0140658
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1 KAT6A

1.32e-04562417GO:0003712
GeneOntologyMolecularFunctionnucleosome binding

SMARCD2 ARID1B ARID1A

1.07e-0398413GO:0031491
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA3 SMARCD2 IRS1 ARID1B BCL9 ARID1A SS18L1 KAT6A

2.17e-031160418GO:0030674
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

ARID1A ATRX CECR2

2.25e-03127413GO:0008094
GeneOntologyMolecularFunctiondisordered domain specific binding

CDKN2A NCOA3

2.90e-0339412GO:0097718
GeneOntologyMolecularFunctionchromatin binding

NCOA3 SMARCD2 ARID1B ARID1A ATRX KAT6A

3.75e-03739416GO:0003682
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A6 COL16A1

4.02e-0346412GO:0030020
GeneOntologyMolecularFunctionhistone acetyltransferase activity

NCOA3 KAT6A

4.92e-0351412GO:0004402
GeneOntologyMolecularFunctionmolecular adaptor activity

NCOA3 SMARCD2 IRS1 ARID1B BCL9 ARID1A SS18L1 KAT6A

5.65e-031356418GO:0060090
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

NCOA3 KAT6A

5.70e-0355412GO:0061733
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.09e-161094011GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

8.66e-132444011GO:0043547
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.68e-113354011GO:0043087
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

CDKN2A TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.06e-104994012GO:0051345
GeneOntologyBiologicalProcessregulation of hydrolase activity

CDKN2A TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

6.10e-088784012GO:0051336
GeneOntologyBiologicalProcesspositive regulation of molecular function

CDKN2A NCOA3 TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B HNRNPK TBC1D3K TBC1D3F

2.33e-0714304014GO:0044093
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

CDKN2A TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

3.37e-0710284012GO:0043085
GeneOntologyBiologicalProcessregulation of nucleotide-excision repair

SMARCD2 ARID1B ARID1A

2.38e-0529403GO:2000819
GeneOntologyBiologicalProcessregulation of G0 to G1 transition

SMARCD2 ARID1B ARID1A

7.36e-0542403GO:0070316
GeneOntologyBiologicalProcessG0 to G1 transition

SMARCD2 ARID1B ARID1A

8.47e-0544403GO:0045023
GeneOntologyBiologicalProcessstem cell population maintenance

CDKN2A NCOA3 BCL9 ARID1A KAT6A

9.10e-05237405GO:0019827
GeneOntologyBiologicalProcessmaintenance of cell number

CDKN2A NCOA3 BCL9 ARID1A KAT6A

1.00e-04242405GO:0098727
GeneOntologyBiologicalProcessmyoblast differentiation

SMARCD2 ARID1B BCL9 ARID1A

1.37e-04136404GO:0045445
GeneOntologyBiologicalProcesspositive regulation of myoblast differentiation

SMARCD2 ARID1B ARID1A

1.56e-0454403GO:0045663
GeneOntologyBiologicalProcessnucleosome organization

SMARCD2 ARID1A ATRX KAT6A

1.62e-04142404GO:0034728
GeneOntologyBiologicalProcessneuron-neuron synaptic transmission

CACNA1A ARID1B

2.39e-0412402GO:0007270
GeneOntologyBiologicalProcesschromatin organization

NCOA3 SMARCD2 ARID1B ARID1A ATRX CECR2 SS18L1 KAT6A

2.74e-04896408GO:0006325
GeneOntologyBiologicalProcesscell junction organization

CACNA1A ILDR1 SYNPO COL16A1 DRP2 BSN GPR158 HNRNPK

4.80e-04974408GO:0034330
GeneOntologyBiologicalProcesssynaptic signaling

CACNA1A SYNPO ARID1B DRP2 BSN GPR158 STXBP5L HNRNPK

4.86e-04976408GO:0099536
GeneOntologyBiologicalProcesschromatin remodeling

NCOA3 SMARCD2 ARID1B ARID1A ATRX CECR2 KAT6A

4.97e-04741407GO:0006338
GeneOntologyBiologicalProcesssignal transduction by p53 class mediator

CDKN2A ATRX HNRNPK KAT6A

5.02e-04191404GO:0072331
GeneOntologyBiologicalProcessprotein-DNA complex organization

NCOA3 SMARCD2 ARID1B ARID1A ATRX CECR2 SS18L1 KAT6A

5.68e-04999408GO:0071824
GeneOntologyBiologicalProcessnucleotide-excision repair

SMARCD2 ARID1B ARID1A

6.61e-0488403GO:0006289
GeneOntologyBiologicalProcessregulation of myoblast differentiation

SMARCD2 ARID1B ARID1A

7.53e-0492403GO:0045661
GeneOntologyBiologicalProcessregulation of G1/S transition of mitotic cell cycle

CDKN2A SMARCD2 ARID1B ARID1A

7.55e-04213404GO:2000045
GeneOntologyBiologicalProcessregulation of mitotic metaphase/anaphase transition

SMARCD2 ARID1B ARID1A

8.26e-0495403GO:0030071
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair

SMARCD2 ARID1B ARID1A

8.26e-0495403GO:2000781
GeneOntologyBiologicalProcessnucleosome disassembly

SMARCD2 ARID1A

8.27e-0422402GO:0006337
GeneOntologyBiologicalProcessregulation of metaphase/anaphase transition of cell cycle

SMARCD2 ARID1B ARID1A

9.05e-0498403GO:1902099
GeneOntologyBiologicalProcessregulation of T cell differentiation

CDKN2A SMARCD2 ARID1B ARID1A

9.41e-04226404GO:0045580
GeneOntologyBiologicalProcessmetaphase/anaphase transition of mitotic cell cycle

SMARCD2 ARID1B ARID1A

9.59e-04100403GO:0007091
GeneOntologyBiologicalProcessprotein-DNA complex disassembly

SMARCD2 ARID1A

9.85e-0424402GO:0032986
GeneOntologyBiologicalProcessapoptotic DNA fragmentation

CDKN2A CECR2

9.85e-0424402GO:0006309
GeneOntologyBiologicalProcessmetaphase/anaphase transition of cell cycle

SMARCD2 ARID1B ARID1A

1.04e-03103403GO:0044784
GeneOntologyBiologicalProcesssomatic stem cell population maintenance

CDKN2A BCL9 KAT6A

1.20e-03108403GO:0035019
GeneOntologyBiologicalProcessregulation of cell cycle G1/S phase transition

CDKN2A SMARCD2 ARID1B ARID1A

1.29e-03246404GO:1902806
GeneOntologyBiologicalProcessregulation of sister chromatid segregation

SMARCD2 ARID1B ARID1A

1.30e-03111403GO:0033045
GeneOntologyBiologicalProcessregulation of neurotransmitter secretion

CACNA1A GPR158 STXBP5L

1.55e-03118403GO:0046928
GeneOntologyBiologicalProcessregulation of signal transduction by p53 class mediator

CDKN2A HNRNPK KAT6A

1.58e-03119403GO:1901796
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

CACNA1A SYNPO BSN GPR158 STXBP5L HNRNPK

1.63e-03663406GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

CACNA1A SYNPO BSN GPR158 STXBP5L HNRNPK

1.64e-03664406GO:0099177
GeneOntologyBiologicalProcessregulation of lymphocyte differentiation

CDKN2A SMARCD2 ARID1B ARID1A

1.72e-03266404GO:0045619
GeneOntologyBiologicalProcessregulation of chromosome organization

SMARCD2 ARID1B ARID1A ATRX

1.72e-03266404GO:0033044
GeneOntologyBiologicalProcessG1/S transition of mitotic cell cycle

CDKN2A SMARCD2 ARID1B ARID1A

1.84e-03271404GO:0000082
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

CACNA1A SYNPO ARID1B BSN GPR158 STXBP5L HNRNPK

1.89e-03931407GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

CACNA1A SYNPO ARID1B BSN GPR158 STXBP5L HNRNPK

1.89e-03931407GO:0007268
GeneOntologyBiologicalProcesssynapse organization

CACNA1A SYNPO DRP2 BSN GPR158 HNRNPK

1.92e-03685406GO:0050808
GeneOntologyBiologicalProcesstrans-synaptic signaling

CACNA1A SYNPO ARID1B BSN GPR158 STXBP5L HNRNPK

1.98e-03939407GO:0099537
GeneOntologyCellularComponentbBAF complex

SMARCD2 ARID1B ARID1A

8.32e-0710413GO:0140092
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

SMARCD2 ARID1B ARID1A CECR2 SS18L1

1.21e-0696415GO:0070603
GeneOntologyCellularComponentbrahma complex

SMARCD2 ARID1B ARID1A

2.51e-0614413GO:0035060
GeneOntologyCellularComponentchromatin

ETV1 CDKN2A NCOA3 SMARCD2 RHOXF2B ARID1B ARID1A ATRX RHOXF2 CECR2 HNRNPK SS18L1 KAT6A

2.88e-0614804113GO:0000785
GeneOntologyCellularComponentnBAF complex

ARID1B ARID1A SS18L1

3.85e-0616413GO:0071565
GeneOntologyCellularComponentATPase complex

SMARCD2 ARID1B ARID1A CECR2 SS18L1

5.19e-06129415GO:1904949
GeneOntologyCellularComponentSWI/SNF complex

SMARCD2 ARID1B ARID1A

2.74e-0530413GO:0016514
GeneOntologyCellularComponentnpBAF complex

ARID1B ARID1A

3.36e-0414412GO:0071564
GeneOntologyCellularComponentnuclear protein-containing complex

NCOA3 SMARCD2 ARID1B BCL9 ARID1A CECR2 RBM41 HNRNPK SS18L1

1.17e-031377419GO:0140513
HumanPhenoAspiration pneumonia

COL4A6 ARID1B ARID1A KAT6A

3.39e-0595114HP:0011951
HumanPhenoSandal gap

SMARCD2 ARID1B ARID1A KAT6A

3.53e-0596114HP:0001852
HumanPhenoGastrointestinal dysmotility

CACNA1A CDKN2A COL4A6 HNRNPK

7.45e-05116114HP:0002579
HumanPhenoAbnormal gastrointestinal motility

CACNA1A CDKN2A COL4A6 HNRNPK

7.96e-05118114HP:0030895
HumanPhenoMyopia

COL4A6 ARID1B ARID1A ATRX HNRNPK KAT6A

1.39e-04447116HP:0000545
HumanPhenoAbnormality of upper lip vermillion

CACNA1A ARID1B ARID1A ATRX HNRNPK KAT6A

1.72e-04464116HP:0011339
HumanPhenoConical tooth

SMARCD2 ARID1B KAT6A

1.85e-0455113HP:0000698
HumanPhenoThyroid carcinoma

CDKN2A ARID1B ARID1A

2.06e-0457113HP:0002890
HumanPhenoNeoplasm of the endocrine system

CDKN2A ARID1B ARID1A ATRX

2.30e-04155114HP:0100568
HumanPhenoAbnormal consumption behavior

CACNA1A CDKN2A ARID1B ARID1A ATRX

2.32e-04299115HP:0040202
HumanPhenoThin eyebrow

CACNA1A HNRNPK KAT6A

2.40e-0460113HP:0045074
HumanPhenoBroad nasal tip

ARID1B ARID1A HNRNPK KAT6A

2.54e-04159114HP:0000455
HumanPhenoAbnormal stomach morphology

CACNA1A CDKN2A COL4A6 ARID1B ATRX HNRNPK KAT6A

2.61e-04742117HP:0002577
HumanPhenoPneumonia

COL4A6 SMARCD2 ARID1B ARID1A KAT6A

2.80e-04311115HP:0002090
HumanPhenoNeoplasm of the gastrointestinal tract

CDKN2A COL4A6 ARID1B ARID1A ATRX

2.88e-04313115HP:0007378
HumanPhenoHypoplastic fifth fingernail

ARID1B ARID1A

3.80e-0414112HP:0008398
HumanPhenoParadoxical increased cortisol secretion on dexamethasone suppression test

CDKN2A ATRX

5.00e-0416112HP:0003466
HumanPhenoIncreased urinary cortisol level

CDKN2A ATRX

5.00e-0416112HP:0012030
HumanPhenoProminent eyelashes

ARID1B ARID1A

5.67e-0417112HP:0011231
HumanPhenoOral aversion

ARID1B ARID1A

5.67e-0417112HP:0012523
HumanPhenoBifid nasal tip

HNRNPK KAT6A

6.37e-0418112HP:0000456
HumanPhenoIntellectual disability, severe

ARID1B ARID1A ATRX HNRNPK KAT6A

6.38e-04371115HP:0010864
HumanPhenoDigestive system neoplasm

CDKN2A COL4A6 ARID1B ARID1A ATRX

6.63e-04374115HP:0034930
HumanPhenoHypoplastic fifth toenail

ARID1B ARID1A

7.11e-0419112HP:0011937
HumanPhenoAbnormal urine hormone level

CDKN2A ATRX

7.11e-0419112HP:0012029
HumanPhenoNeoplasm of the thyroid gland

CDKN2A ARID1B ARID1A

7.19e-0487113HP:0100031
HumanPhenoAbnormal nasal tip morphology

ARID1B ARID1A ATRX HNRNPK KAT6A

7.67e-04386115HP:0000436
HumanPhenoHirsutism

SMARCD2 ARID1B ARID1A ATRX

8.20e-04216114HP:0001007
HumanPhenoCoxa valga

ARID1B ATRX HNRNPK

8.47e-0492113HP:0002673
HumanPhenoMacrostomia

ARID1B ARID1A ATRX KAT6A

8.79e-04220114HP:0000181
HumanPhenoWide mouth

ARID1B ARID1A ATRX KAT6A

8.79e-04220114HP:0000154
HumanPhenoIntermittent diarrhea

CDKN2A ATRX

9.57e-0422112HP:0002254
MousePhenopremature death

ETV1 CACNA1A CDKN2A NCOA3 IRS1 BSN CECR2 SS18L1 KAT6A

3.45e-051051249MP:0002083
MousePhenoabnormal synaptic acetylcholine release

CACNA1A STXBP5L

5.90e-057242MP:0004836
DomainTBC

TBC1D3E TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

4.63e-18494010SM00164
DomainRabGAP-TBC

TBC1D3E TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.09e-17534010PF00566
DomainTBC_RABGAP

TBC1D3E TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.63e-17554010PS50086
DomainRab-GTPase-TBC_dom

TBC1D3E TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.63e-17554010IPR000195
DomainBAF250_C

ARID1B ARID1A

4.47e-062402IPR033388
DomainBAF250_C

ARID1B ARID1A

4.47e-062402PF12031
DomainBAF250/Osa

ARID1B ARID1A

4.47e-062402IPR021906
Domain-

ARID1B ARID1A

4.61e-04154021.10.150.60
DomainARID

ARID1B ARID1A

4.61e-0415402PF01388
DomainBRIGHT

ARID1B ARID1A

4.61e-0415402SM00501
DomainARID_dom

ARID1B ARID1A

4.61e-0415402IPR001606
DomainARID

ARID1B ARID1A

4.61e-0415402PS51011
DomainZnf_FYVE_PHD

BSN ATRX KAT6A

3.81e-03147403IPR011011
DomainCollagen

COL4A6 COL16A1

1.43e-0285402PF01391
DomainCollagen

COL4A6 COL16A1

1.43e-0285402IPR008160
Domain-

RNF123 BSN ATRX KAT6A

1.52e-024494043.30.40.10
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K

9.62e-1399339M46448
PathwayWP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1

CDKN2A SMARCD2 ARID1B ARID1A

7.49e-0731334M39522
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

CDKN2A SMARCD2 ARID1B ARID1A SS18L1

2.56e-0695335M48268
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

SMARCD2 ARID1B ARID1A SS18L1

2.62e-0642334M48237
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

CDKN2A SMARCD2 ARID1B ARID1A SS18L1

1.54e-05137335M48232
PathwayWP_KLEEFSTRA_SYNDROME

SMARCD2 ARID1B ARID1A

4.10e-0529333M48076
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

SMARCD2 ARID1B ARID1A

7.27e-0535333M47969
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_PIWI_INTERACTING_RNAS_PIRNAS

SMARCD2 ARID1B ARID1A SS18L1

7.40e-0597334M48262
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

SMARCD2 ARID1B ARID1A

8.60e-0537333M27797
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

SMARCD2 ARID1B ARID1A SS18L1

3.22e-04142334M48257
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

ARID1A ATRX KAT6A

4.62e-0465333M39682
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL4A6 IRS1 COL16A1

6.77e-0474333M160
PathwayREACTOME_RMTS_METHYLATE_HISTONE_ARGININES

SMARCD2 ARID1B ARID1A

7.89e-0478333M27234
PathwayWP_TYPE_II_DIABETES_MELLITUS

CACNA1A IRS1

1.19e-0322332M39658
PathwayBIOCARTA_VDR_PATHWAY

NCOA3 ARID1A

1.19e-0322332MM1370
PathwayWP_THERMOGENESIS

SMARCD2 ARID1B ARID1A

2.02e-03108333M39746
PathwayWP_ANDROGEN_RECEPTOR_NETWORK_IN_PROSTATE_CANCER

SMARCD2 ARID1B ARID1A

2.13e-03110333M48043
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.40e-3311411116863688
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3G TBC1D3B TBC1D3F

3.13e-127441716625196
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3 TBC1D3D TBC1D3F

6.08e-09441312359748
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3 TBC1D3D TBC1D3F

6.08e-0944138406013
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

CDKN2A SMARCD2 ARID1B ARID1A SS18L1

1.39e-086541526655900
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C

1.52e-08541312604796
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3 TBC1D3D TBC1D3F

1.52e-0854138471161
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

SMARCD2 ARID1B ARID1A ATRX SS18L1 KAT6A

3.03e-0815741630186101
Pubmed

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

SMARCD2 ARID1B ARID1A

1.81e-071041312665591
Pubmed

Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.

ARID1B ARID1A SS18L1

6.85e-071541323785148
Pubmed

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.

SMARCD2 ARID1B ARID1A

6.85e-071541311263494
Pubmed

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.

SMARCD2 ARID1B ARID1A

6.85e-071541311175787
Pubmed

Regulation of dendritic development by neuron-specific chromatin remodeling complexes.

SMARCD2 ARID1B ARID1A

6.85e-071541317920018
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA3 RNF123 ARID1B DRP2 BSN BCL9 ARID1A SS18L1

6.88e-0763841831182584
Pubmed

Identification of a polymorphic, neuron-specific chromatin remodeling complex.

SMARCD2 ARID1B ARID1A

1.02e-061741312368262
Pubmed

The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.

SMARCD2 ARID1B ARID1A

1.02e-061741311078522
Pubmed

BAF complexes facilitate decatenation of DNA by topoisomerase IIα.

SMARCD2 ARID1B ARID1A

1.23e-061841323698369
Pubmed

Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.

ARID1B ARID1A

1.36e-06241234386776
Pubmed

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.

ARID1B ARID1A

1.36e-06241223202128
Pubmed

Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.

RHOXF2B RHOXF2

1.36e-06241212087094
Pubmed

ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.

ARID1B ARID1A

1.36e-06241233890484
Pubmed

ARID1B is a specific vulnerability in ARID1A-mutant cancers.

ARID1B ARID1A

1.36e-06241224562383
Pubmed

ETV1 positively regulates transcription of tumor suppressor ARF.

ETV1 CDKN2A

1.36e-06241224157551
Pubmed

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.

ARID1B ARID1A

1.36e-06241237611161
Pubmed

Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.

ARID1B ARID1A

1.36e-06241232791957
Pubmed

ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.

ARID1B ARID1A

1.36e-06241229890703
Pubmed

SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.

ARID1B ARID1A

1.36e-06241224788099
Pubmed

Rhox homeobox gene cluster: recent duplication of three family members.

RHOXF2B RHOXF2

1.36e-06241216496311
Pubmed

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.

ARID1B ARID1A

1.36e-06241228967863
Pubmed

Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.

ARID1B ARID1A

1.36e-06241233052929
Pubmed

NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia.

NCOA3 KAT6A

1.36e-06241217805331
Pubmed

Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.

RHOXF2B RHOXF2

1.36e-06241216465597
Pubmed

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.

ARID1B ARID1A

1.36e-06241227562491
Pubmed

Cloning and characterization of the 5'-flanking region of the Ehox gene.

RHOXF2B RHOXF2

1.36e-06241216414020
Pubmed

Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.

SMARCD2 ARID1B ARID1A

1.45e-061941316932743
Pubmed

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

SMARCD2 ARID1B ARID1A

1.45e-061941312110891
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

SMARCD2 ARID1B ARID1A

2.65e-062341330962207
Pubmed

Diversity and specialization of mammalian SWI/SNF complexes.

SMARCD2 ARID1B ARID1A

2.65e-06234138804307
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA3 ARID1B BCL9 ARID1A

2.85e-068341428794006
Pubmed

SWI/SNF chromatin remodeling and cancer.

SMARCD2 ARID1B ARID1A

3.03e-062441311790558
Pubmed

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.

SMARCD2 ARID1B ARID1A

3.03e-062441310078207
Pubmed

The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.

SMARCD2 ARID1B ARID1A

3.03e-062441312215535
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1

3.38e-0635141638297188
Pubmed

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.

SMARCD2 ARID1B ARID1A

3.88e-062641310778858
Pubmed

Loss of ARID1B and SMARCB1 expression are specific for the diagnosis of dedifferentiated/undifferentiated carcinoma in tumours of the upper gynaecological tract and cervix.

ARID1B ARID1A

4.06e-06341233432679
Pubmed

Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.

ARID1B ARID1A

4.06e-06341221647563
Pubmed

TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.

ARID1B ARID1A

4.06e-06341234044070
Pubmed

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes.

ARID1B ARID1A

4.06e-06341226716708
Pubmed

The rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development.

RHOXF2B RHOXF2

4.06e-06341218562707
Pubmed

ARID1A suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/CDKN2A regulatory axis.

CDKN2A ARID1A

4.06e-06341228942143
Pubmed

Diversity of human copy number variation and multicopy genes.

TBC1D3E TBC1D3G

4.06e-06341221030649
Pubmed

MOZ-mediated repression of p16(INK) (4) (a) is critical for the self-renewal of neural and hematopoietic stem cells.

CDKN2A KAT6A

4.06e-06341224307508
Pubmed

The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c.

RHOXF2B RHOXF2

4.06e-06341218077458
Pubmed

Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

ARID1B ARID1A

4.06e-06341222426308
Pubmed

Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer.

ARID1B ARID1A

4.06e-06341224382590
Pubmed

A fully automated artificial intelligence method for non-invasive, imaging-based identification of genetic alterations in glioblastomas.

CDKN2A ATRX

4.06e-06341232678261
Pubmed

The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models.

NCOA3 IRS1

4.06e-06341222859932
Pubmed

Treatments, prognostic factors, and genetic heterogeneity in advanced cholangiocarcinoma: A multicenter real-world study.

CDKN2A ARID1A

4.06e-06341238457226
Pubmed

ARID1A, ARID1B, and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer.

ARID1B ARID1A

4.06e-06341234512623
Pubmed

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.

SMARCD2 ARID1B ARID1A

4.36e-062741329374058
Pubmed

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.

SMARCD2 ARID1B ARID1A

4.88e-062841330037996
Pubmed

REST repression of neuronal genes requires components of the hSWI.SNF complex.

SMARCD2 ARID1B ARID1A

4.88e-062841312192000
Pubmed

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.

ARID1B ARID1A SS18L1

5.44e-062941319279220
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

NCOA3 SMARCD2 ARID1B ARID1A ATRX

6.02e-0622041535785414
Pubmed

Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.

SMARCD2 ARID1B ARID1A

6.04e-063041331043422
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

ACTR1B NCOA3 SMARCD2 ARID1B ARID1A CECR2

6.93e-0639841635016035
Pubmed

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development.

CDKN2A KAT6A

8.12e-06441225605372
Pubmed

TBC1D3, a hominoid-specific gene, delays IRS-1 degradation and promotes insulin signaling by modulating p70 S6 kinase activity.

IRS1 TBC1D3

8.12e-06441222348058
Pubmed

Antagonistic interaction between Ezh2 and Arid1a coordinates root patterning and development via Cdkn2a in mouse molars.

CDKN2A ARID1A

8.12e-06441231259687
Pubmed

Undifferentiated Endometrial Carcinomas Show Frequent Loss of Core Switch/Sucrose Nonfermentable Complex Proteins.

ARID1B ARID1A

8.12e-06441228863077
Pubmed

Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.

ARID1B ARID1A

8.12e-06441215170388
Pubmed

Mutant IDH1 Promotes Glioma Formation In Vivo.

CDKN2A ATRX

8.12e-06441229719265
Pubmed

Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.

ARID1B ARID1A

8.12e-06441211988099
Pubmed

Rhox: a new homeobox gene cluster.

RHOXF2B RHOXF2

8.12e-06441215707895
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

SMARCD2 ARID1B ARID1A

9.69e-063541332504627
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

SMARCD2 ARID1B ARID1A

1.15e-053741324335282
Pubmed

Recent advances in understanding chromatin remodeling by Swi/Snf complexes.

ARID1B ARID1A

1.35e-05541212672490
Pubmed

Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.

ARID1B ARID1A

1.35e-05541212200431
Pubmed

MOZ and BMI1 act synergistically to maintain hematopoietic stem cells.

CDKN2A KAT6A

1.35e-05541227773671
Pubmed

Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.

RHOXF2B RHOXF2

1.35e-05541214648851
Pubmed

Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations.

ARID1B ARID1A

1.35e-05541238489371
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

SMARCD2 ARID1B ARID1A

1.46e-054041334585037
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

1.56e-0526841533640491
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

ARID1B ARID1A

2.03e-05641216230384
Pubmed

Numerous BAF complex genes are mutated in Coffin-Siris syndrome.

ARID1B ARID1A

2.03e-05641225081545
Pubmed

Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma.

ARID1B ARID1A

2.84e-05741223540691
Pubmed

Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu.

ETV1 NCOA3

3.78e-05841214747462
Pubmed

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling.

SMARCD2 ARID1B ARID1A

3.82e-055541335945219
Pubmed

Coffin-Siris Syndrome

ARID1B ARID1A

4.86e-05941223556151
Pubmed

Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.

ARID1B ARID1A

4.86e-05941220086098
Pubmed

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.

NCOA3 ARID1B

4.86e-05941219176441
Pubmed

The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.

ARID1B ARID1A

4.86e-05941237805104
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

SMARCD2 ARID1B ARID1A

5.22e-056141320305087
Pubmed

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.

NCOA3 ARID1B

6.07e-051041216751102
Pubmed

Nomenclature of the ARID family of DNA-binding proteins.

ARID1B ARID1A

6.07e-051041215922553
Pubmed

ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF.

ARID1B ARID1A

6.07e-051041223129809
Pubmed

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.

RHOXF2B RHOXF2

6.07e-051041221972064
Pubmed

Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.

NCOA3 ARID1A

7.41e-051141218003620
Pubmed

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

ETV1 CDKN2A IRS1

8.57e-057241324509480
Pubmed

Arid1a regulates bladder urothelium formation and maintenance.

ARID1B ARID1A

8.88e-051241235283102
InteractionCRX interactions

NCOA3 SMARCD2 ARID1B MYO15B BCL9 ARID1A RHOXF2 SS18L1

2.50e-08254398int:CRX
InteractionPAX8 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1

6.85e-08111396int:PAX8
InteractionTBR1 interactions

NCOA3 SMARCD2 RNF123 ARID1B BCL9 ARID1A

7.63e-08113396int:TBR1
InteractionTBXT interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1

8.92e-08116396int:TBXT
InteractionFEV interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A ATRX SS18L1

1.11e-07203397int:FEV
InteractionPAX7 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1

1.33e-07124396int:PAX7
InteractionGCM1 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

1.98e-0768395int:GCM1
InteractionERG interactions

ETV1 NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1

2.10e-07223397int:ERG
InteractionETV4 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

2.14e-0769395int:ETV4
InteractionSOX7 interactions

NCOA3 SMARCD2 ARID1B ARID1A CECR2

5.09e-0782395int:SOX7
InteractionKLF4 interactions

NCOA3 SMARCD2 ARID1B MYO15B BCL9 ARID1A

5.99e-07160396int:KLF4
InteractionFOXI1 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

9.05e-0792395int:FOXI1
InteractionTLX1 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A KAT6A

1.01e-06175396int:TLX1
InteractionSOX17 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

1.06e-0695395int:SOX17
InteractionSOX9 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

1.18e-0697395int:SOX9
InteractionSP7 interactions

NCOA3 SMARCD2 RNF123 ARID1B BCL9 ARID1A SS18L1

1.69e-06304397int:SP7
InteractionMYOD1 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1

1.84e-06194396int:MYOD1
InteractionBRD9 interactions

SMARCD2 ARID1B ARID1A ATRX SS18L1

2.98e-06117395int:BRD9
InteractionETS1 interactions

NCOA3 SMARCD2 ARID1B ARID1A SS18L1

3.51e-06121395int:ETS1
InteractionPAX9 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

4.99e-06130395int:PAX9
InteractionTEX13B interactions

SMARCD2 ARID1B ARID1A

7.47e-0620393int:TEX13B
InteractionNFIB interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

7.68e-06142395int:NFIB
InteractionBICRA interactions

SMARCD2 ARID1B ARID1A SS18L1

8.41e-0667394int:BICRA
InteractionHNF4A interactions

NCOA3 SMARCD2 ARID1B ARID1A ATRX SS18L1

1.37e-05275396int:HNF4A
InteractionEGR2 interactions

NCOA3 ARID1B BCL9 ARID1A SS18L1

1.89e-05171395int:EGR2
InteractionSTK11IP interactions

SMARCD2 ARID1B ARID1A SS18L1

1.97e-0583394int:STK11IP
InteractionSMAD3 interactions

NCOA3 IRS1 ARID1B ARID1A HNRNPK SS18L1 KAT6A

2.10e-05447397int:SMAD3
InteractionARID1B interactions

NCOA3 SMARCD2 ARID1B ARID1A SS18L1

2.23e-05177395int:ARID1B
InteractionSS18 interactions

SMARCD2 ARID1B ARID1A SS18L1

2.48e-0588394int:SS18
InteractionLHX3 interactions

SMARCD2 ARID1B BCL9 ARID1A SS18L1

2.76e-05185395int:LHX3
InteractionFOS interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1

2.78e-05312396int:FOS
InteractionGATA3 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

2.91e-05187395int:GATA3
InteractionSOX10 interactions

NCOA3 ARID1B BCL9 ARID1A

2.96e-0592394int:SOX10
InteractionNFIA interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

2.98e-05188395int:NFIA
InteractionDPF3 interactions

SMARCD2 ARID1B ARID1A SS18L1

3.36e-0595394int:DPF3
InteractionDPF1 interactions

SMARCD2 ARID1B ARID1A SS18L1

3.36e-0595394int:DPF1
InteractionBCL7B interactions

SMARCD2 ARID1B ARID1A SS18L1

3.36e-0595394int:BCL7B
InteractionKLF5 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

3.55e-05195395int:KLF5
InteractionSS18L1 interactions

SMARCD2 ARID1B ARID1A SS18L1

3.79e-0598394int:SS18L1
InteractionGATA2 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A

3.91e-05199395int:GATA2
InteractionLHX1 interactions

SMARCD2 ARID1B BCL9 ARID1A

4.61e-05103394int:LHX1
InteractionNFIC interactions

NCOA3 SMARCD2 ARID1B ARID1A HNRNPK

5.05e-05210395int:NFIC
InteractionSMARCD3 interactions

SMARCD2 ARID1B ARID1A SS18L1

5.35e-05107394int:SMARCD3
InteractionACTG1 interactions

CDKN2A ACTR1B SMARCD2 RNF123 ARID1B ARID1A KAT6A

5.49e-05520397int:ACTG1
InteractionPAX6 interactions

NCOA3 SMARCD2 ARID1B BCL9 ARID1A SS18L1

6.77e-05366396int:PAX6
InteractionRBM41 interactions

RNF123 RBM41 HNRNPK

6.79e-0541393int:RBM41
InteractionBCL7C interactions

SMARCD2 ARID1B ARID1A SS18L1

7.09e-05115394int:BCL7C
InteractionMLLT1 interactions

SMARCD2 RNF123 ARID1B ARID1A

9.21e-05123394int:MLLT1
InteractionBCL7A interactions

SMARCD2 ARID1B ARID1A SS18L1

9.21e-05123394int:BCL7A
InteractionCIMIP2A interactions

RNF123 RHOXF2

1.01e-048392int:CIMIP2A
InteractionTBC1D3F interactions

TBC1D3 TBC1D3F

1.01e-048392int:TBC1D3F
InteractionPBRM1 interactions

SMARCD2 ARID1B ARID1A SS18L1 KAT6A

1.33e-04258395int:PBRM1
InteractionPHF10 interactions

SMARCD2 ARID1B ARID1A SS18L1

1.48e-04139394int:PHF10
InteractionSOX15 interactions

NCOA3 ARID1B BCL9 ARID1A

1.56e-04141394int:SOX15
InteractionFAM168A interactions

SMARCD2 ARID1B RHOXF2 SS18L1

1.60e-04142394int:FAM168A
InteractionRIMBP2 interactions

CACNA1A KAT6A

1.63e-0410392int:RIMBP2
InteractionTPRX2 interactions

SMARCD2 ARID1B ARID1A

1.73e-0456393int:TPRX2
InteractionELF5 interactions

SMARCD2 ARID1B ARID1A SS18L1

1.83e-04147394int:ELF5
InteractionDRP2 interactions

DRP2 HNRNPK

1.99e-0411392int:DRP2
InteractionTBC1D3 interactions

TBC1D3 TBC1D3F

1.99e-0411392int:TBC1D3
InteractionARID2 interactions

SMARCD2 ARID1B ARID1A SS18L1

2.14e-04153394int:ARID2
InteractionSMARCE1 interactions

NCOA3 SMARCD2 ARID1B ARID1A SS18L1

2.19e-04287395int:SMARCE1
InteractionFLI1 interactions

SMARCD2 ARID1B ARID1A

2.34e-0462393int:FLI1
InteractionSMARCA4 interactions

CDKN2A SMARCD2 ARID1B ARID1A SS18L1 KAT6A

2.41e-04462396int:SMARCA4
InteractionCLIC3 interactions

TBC1D3 TBC1D3C TBC1D3K

2.46e-0463393int:CLIC3
InteractionLHX4 interactions

SMARCD2 ARID1B BCL9 ARID1A

2.92e-04166394int:LHX4
InteractionALG13 interactions

NCOA3 ARID1B BCL9 ARID1A

4.22e-04183394int:ALG13
InteractionLHX2 interactions

SMARCD2 ARID1B BCL9 ARID1A

4.22e-04183394int:LHX2
InteractionSMARCD2 interactions

SMARCD2 ARID1B ARID1A SS18L1

4.22e-04183394int:SMARCD2
InteractionSS18L2 interactions

SMARCD2 ARID1B ARID1A

4.27e-0476393int:SS18L2
InteractionMEGF6 interactions

CACNA1A RNF123

4.30e-0416392int:MEGF6
InteractionATN1 interactions

ATRX RHOXF2 SS18L1 KAT6A

4.58e-04187394int:ATN1
InteractionNR3C1 interactions

NCOA3 RNF123 ARID1B DRP2 BSN BCL9 ARID1A SS18L1

4.67e-04974398int:NR3C1
InteractionHNF1B interactions

NCOA3 ARID1B BCL9 ARID1A

4.86e-04190394int:HNF1B
InteractionSMARCD1 interactions

SMARCD2 ARID1B ARID1A ATRX SS18L1

5.37e-04349395int:SMARCD1
InteractionRBPMS2 interactions

RHOXF2 RBM41 HNRNPK

5.53e-0483393int:RBPMS2
InteractionIRF1 interactions

SMARCD2 ARID1B ARID1A

5.53e-0483393int:IRF1
InteractionSMARCC2 interactions

NCOA3 SMARCD2 ARID1B ARID1A SS18L1

5.66e-04353395int:SMARCC2
InteractionPAX2 interactions

NCOA3 ARID1B BCL9

5.93e-0485393int:PAX2
InteractionIRF4 interactions

NCOA3 ARID1B ARID1A

5.93e-0485393int:IRF4
InteractionGSC interactions

NCOA3 ARID1B BCL9

6.35e-0487393int:GSC
InteractionSMARCB1 interactions

SMARCD2 ARID1B ARID1A SS18L1 KAT6A

6.50e-04364395int:SMARCB1
InteractionMORC2 interactions

NCOA3 ATRX KAT6A

7.24e-0491393int:MORC2
InteractionTLE3 interactions

NCOA3 ARID1B BCL9 ARID1A CECR2

7.52e-04376395int:TLE3
InteractionPCDHB14 interactions

RNF123 HNRNPK

8.23e-0422392int:PCDHB14
InteractionSMARCC1 interactions

NCOA3 SMARCD2 ARID1B ARID1A SS18L1

8.27e-04384395int:SMARCC1
InteractionSMAD2 interactions

NCOA3 SMARCD2 RNF123 ARID1B ARID1A

8.37e-04385395int:SMAD2
InteractionNUCKS1 interactions

ARID1A ATRX CECR2 KAT6A

8.42e-04220394int:NUCKS1
InteractionHAPSTR1 interactions

CDKN2A SMARCD2 SYNPO ARID1B BSN ARID1A ATRX

9.45e-04829397int:HAPSTR1
InteractionNFIX interactions

SMARCD2 ARID1B ARID1A HNRNPK

9.46e-04227394int:NFIX
InteractionCREBBP interactions

NCOA3 ARID1B ARID1A ATRX SS18L1 KAT6A

9.51e-04599396int:CREBBP
InteractionING1 interactions

CDKN2A ARID1A ATRX

1.04e-03103393int:ING1
InteractionSIRT1 interactions

NCOA3 SMARCD2 IRS1 HNRNPK KAT6A

1.13e-03412395int:SIRT1
InteractionH4C9 interactions

RNF123 ATRX KAT6A

1.19e-03108393int:H4C9
InteractionTEX13A interactions

SMARCD2 MYO15B

1.24e-0327392int:TEX13A
InteractionETV1 interactions

ETV1 NCOA3

1.43e-0329392int:ETV1
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3E TBC1D3 TBC1D3L TBC1D3H TBC1D3I TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

8.40e-191494111chr17q12
Cytoband17q12

TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F

2.97e-089941517q12
CytobandXq22

COL4A6 DRP2

1.78e-0422412Xq22
Cytoband3q13.33

ILDR1 STXBP5L

3.33e-04304123q13.33
CytobandEnsembl 112 genes in cytogenetic band chrXq22

COL4A6 DRP2 RBM41

4.96e-04172413chrXq22
CytobandXq24

RHOXF2B RHOXF2

1.51e-0364412Xq24
CytobandEnsembl 112 genes in cytogenetic band chrXq24

RHOXF2B RHOXF2

2.41e-0381412chrXq24
GeneFamilyAT-rich interaction domain containing

ARID1B ARID1A

1.47e-0415222418
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA3 KAT6A

1.90e-0417222486
GeneFamilyCollagens

COL4A6 COL16A1

1.42e-0346222490
GeneFamilyPRD class homeoboxes and pseudogenes

RHOXF2B RHOXF2

5.54e-0392222521
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

9.18e-1490419PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

COL4A6 TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

7.13e-122134110PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

COL4A6 TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

7.13e-122134110PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

COL4A6 TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.52e-112424110PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.65e-09281419PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.65e-09281419PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

8.22e-09320419PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

COL4A6 ACTR1B TMTC2 TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K KAT6A TBC1D3F

2.18e-0614664113PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

ACTR1B TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K KAT6A TBC1D3F

4.14e-0610754111PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

IRS1 TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.29e-0510494110PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

COL4A6 TBC1D3 TBC1D3L TBC1D3H TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

5.13e-0511534110PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

SYNPO DRP2 BCL9 ARID1A ATRX

2.61e-04298415Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4

CACNA1A TMTC2 RNF123 ZC3H12C STXBP5L RBM41 SS18L1

4.15e-04721417Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3

CACNA1A TMTC2 RNF123 ZC3H12C STXBP5L RBM41 SS18L1

4.47e-04730417Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ETV1 ACTR1B ILDR1 COL16A1

1.63e-0516641443f84d3cd58e93ce00c241656c4cba27604b4932
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV1 CACNA1A BSN STXBP5L

1.91e-0517341407798461d12d04f3dabff03481c999cb07c5af2f
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV1 CACNA1A BSN STXBP5L

2.00e-05175414c031da47ca63d1133e13530cbf779df9435e22cb
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV1 CACNA1A BSN STXBP5L

2.05e-051764142e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCellB_cells-Activate_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CACNA1A NCOA3 ILDR1 SYNPO

2.94e-05193414b6da81920cf2e55f87ec8d4b2b5530cbf7ba2155
Drugkhellin

COL4A6 ACTR1B NCOA3 COL16A1 KAT6A

5.26e-06171345CID000003828
Drugfoscarnet

CACNA1A COL4A6 ACTR1B COL16A1 BSN

8.78e-06190345CID000003414
Diseaseneuroblastoma (is_implicated_in)

CDKN2A ARID1B ARID1A

1.25e-0710313DOID:769 (is_implicated_in)
DiseaseNeuroblastoma

CDKN2A ARID1B ARID1A ATRX

1.72e-0747314C0027819
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1B ARID1A

1.07e-055312C3281201
Diseasetumor necrosis factor ligand superfamily member 6, soluble form measurement

RNF123 BSN

2.24e-057312EFO_0020797
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

SMARCD2 ARID1A

3.83e-059312DOID:1925 (implicated_via_orthology)
DiseaseCoffin-Siris syndrome

ARID1B ARID1A

8.27e-0513312C0265338
DiseaseAdenocarcinoma Of Esophagus

CDKN2A ARID1A

9.64e-0514312C0279628
DiseaseAdenoid Cystic Carcinoma

ARID1A ATRX KAT6A

1.58e-04100313C0010606
DiseaseLiver carcinoma

CDKN2A IRS1 ARID1B ARID1A GPR158

1.72e-04507315C2239176
DiseaseCCL4 measurement

TBC1D3 TBC1D3F

2.01e-0420312EFO_0004751
DiseaseBreast Carcinoma

CDKN2A NCOA3 ARID1B ARID1A HNRNPK

2.27e-04538315C0678222
DiseaseGranulomatous Slack Skin

CDKN2A ARID1A

2.44e-0422312C0376407
DiseaseNasopharyngeal carcinoma

CDKN2A ARID1A

2.44e-0422312C2931822
DiseaseCarcinoma, Granular Cell

CDKN2A NCOA3 ARID1A

2.46e-04116313C0205644
DiseaseAdenocarcinoma, Tubular

CDKN2A NCOA3 ARID1A

2.46e-04116313C0205645
DiseaseAdenocarcinoma, Oxyphilic

CDKN2A NCOA3 ARID1A

2.46e-04116313C0205642
DiseaseCarcinoma, Cribriform

CDKN2A NCOA3 ARID1A

2.46e-04116313C0205643
DiseaseAdenocarcinoma, Basal Cell

CDKN2A NCOA3 ARID1A

2.46e-04116313C0205641
DiseaseAdenocarcinoma

CDKN2A NCOA3 ARID1A

2.46e-04116313C0001418
DiseaseLymphoma, T-Cell, Cutaneous

CDKN2A ARID1A

2.67e-0423312C0079773
DiseaseSezary Syndrome

CDKN2A ARID1A

3.69e-0427312C0036920
Diseasemacrophage inflammatory protein 1b measurement

TBC1D3 TBC1D3B TBC1D3F

3.92e-04136313EFO_0008219
DiseaseProstatic Neoplasms

ETV1 NCOA3 IRS1 ARID1A KAT6A

4.23e-04616315C0033578
DiseaseMalignant neoplasm of prostate

ETV1 NCOA3 IRS1 ARID1A KAT6A

4.23e-04616315C0376358
Diseaseprostate cancer (is_marker_for)

CDKN2A NCOA3 HNRNPK

5.84e-04156313DOID:10283 (is_marker_for)
DiseaseBurkitt Lymphoma

CDKN2A ARID1A

6.58e-0436312C0006413
Diseasethioredoxin domain-containing protein 12 measurement

RNF123 BSN

7.73e-0439312EFO_0008298
DiseaseNeoplasm of uncertain or unknown behavior of breast

ARID1B ARID1A

8.54e-0441312C0496956
DiseaseBreast adenocarcinoma

ARID1B ARID1A

8.54e-0441312C0858252
Diseasehigh grade glioma (is_implicated_in)

CDKN2A ATRX

8.96e-0442312DOID:3070 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
MYQMLRHMSPPLGLG

CACNA1A

1851

O00555
MPGMPGQSMRVGYTL

COL4A6

1456

Q14031
RMQFPMEMAAAPGRP

COL16A1

1461

Q07092
PNYVGRPKHMRVMAG

ACTR1B

36

P42025
QQGMSMPDVMGRMPY

ARID1B

1331

Q8NFD5
QAPPYPGMNRTDDMM

ARID1B

1556

Q8NFD5
GPFQEMYRPSGMQMH

CECR2

1436

Q9BXF3
MYRPSGMQMHPVQSQ

CECR2

1441

Q9BXF3
KGPPIQFRMMTGRMR

RBM41

336

Q96IZ5
ASMGNRPYGPNMANM

ARID1A

861

O14497
QRIPYMTGGRVMRML

GPR158

516

Q5T848
QPASVLRPMVRGGMY

BSN

2211

Q9UPA5
PTMPREGRPMYQRQM

ETV1

201

P50549
RYMKQAQALGPQMMG

ILDR1

221

Q86SU0
RRHPQRVDPNGYMMM

IRS1

651

P35568
QQGYPMVYPGMIQMP

MYO15B

816

Q96JP2
GMNMGVNLMPTPAYN

KAT6A

1896

Q92794
MRGMYQPVAGGMQPP

ATRX

2456

P46100
PNSYGRRPIQVMMMG

CDKN2A

41

P42771
GIRPSMEMNRMIPGS

BCL9

651

O00512
MQPMVMQGCPYTLPR

DRP2

1

Q13474
SPMVERRMMGQRSPA

SYNPO

536

Q8N3V7
MMFDDRRGRPVGFPM

HNRNPK

241

P61978
GGAAVMRPMMQPQVS

NCOA3

1201

Q9Y6Q9
LMARNMLPFMAVGQP

RHOXF2B

196

P0C7M4
DRAYKGMPMNIRGPM

TBC1D3L

96

B9A6J9
CMDRMGGLMQPPYEV

STXBP5L

901

Q9Y2K9
YQRPGMSPGNRMPMA

SMARCD2

71

Q92925
MMGQRPMAPYRPSQQ

SS18L1

226

O75177
DRAYKGMPMNIRGPM

TBC1D3B

96

A6NDS4
DRAYKGMPMNIRGPM

TBC1D3H

96

P0C7X1
DRAYKGMPMNIRGPM

TBC1D3F

96

A6NER0
GRGNMPMLCPPEYMV

RNF123

541

Q5XPI4
MPRQFAPQSLYNMMG

TMTC2

636

Q8N394
DQAYKGMPMNIRGPM

TBC1D3E

96

A0A087X179
LMARNMLPFMAVGQP

RHOXF2

196

Q9BQY4
DRAYKGMPMNIRGPM

TBC1D3D

96

A0A087WVF3
QDQRPQGQYPSMMMA

ZC3H12C

551

Q9C0D7
DRAYKGMPMNIRGPM

TBC1D3G

96

Q6DHY5
DRAYKGMPMNIRGPM

TBC1D3

96

Q8IZP1
DRAYKGMPMNIRGPM

TBC1D3K

96

A0A087X1G2
DRAYKGMPMNIRGPM

TBC1D3I

96

A0A087WXS9
DRAYKGMPMNIRGPM

TBC1D3C

96

Q6IPX1