Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR2A14 OR1M1 CYSLTR2 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 FPR2 FPR3 MC2R OR4M1 GPR78 MC5R OR5A1 ACKR4 GRM4 GALR2 OR9G9 OR11H6 OR52E2 OR10D4P FZD4 OR51L1 OR51D1 OR4S1 OR52A4P ADGRG2 CXCR6 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 TACR2 OR52W1 LGR6 OR5L2 GPR45 ADGRD1	1.27e-32	884	102	44	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR2A14 OR1M1 CYSLTR2 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 FPR2 FPR3 MC2R OR4M1 GPR78 MC5R OR5A1 HTR3C ACKR4 GRM4 GALR2 OR9G9 OR11H6 OR52E2 OR10D4P FZD4 OR51L1 OR51D1 OR4S1 OR52A4P ADGRG2 FCGR3A CXCR6 FCGR3B OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 TACR2 OR52W1 LGR6 OR5L2 GPR45 ADGRD1	4.06e-28	1353	102	47	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	2.09e-23	431	102	28	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR8D1 OR5D18 OR5L1 OR5AS1 OR5A1 OR5C1 OR5L2	3.99e-06	127	102	7	GO:0005549
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	CYSLTR2 FPR2 FPR3 MC2R MC5R GALR2 TACR2	5.42e-06	133	102	7	GO:0008528
GeneOntologyMolecularFunction	peptide receptor activity	CYSLTR2 FPR2 FPR3 MC2R MC5R GALR2 TACR2	7.60e-06	140	102	7	GO:0001653
GeneOntologyMolecularFunction	immune receptor activity	FPR2 FPR3 ACKR4 FZD4 FCGR3A CXCR6 FCGR3B	2.21e-05	165	102	7	GO:0140375
GeneOntologyMolecularFunction	low-affinity IgG receptor activity	FCGR3A FCGR3B	1.54e-04	4	102	2	GO:0019772
GeneOntologyMolecularFunction	scavenger receptor binding	FPR2 FPR3	2.56e-04	5	102	2	GO:0005124
GeneOntologyMolecularFunction	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	B4GALT1 WDFY3	2.56e-04	5	102	2	GO:0003831
GeneOntologyMolecularFunction	N-formyl peptide receptor activity	FPR2 FPR3	2.56e-04	5	102	2	GO:0004982
GeneOntologyMolecularFunction	alkaline phosphatase activity	ALPI ALPG	3.82e-04	6	102	2	GO:0004035
GeneOntologyMolecularFunction	IgE receptor activity	FCGR3A FCGR3B	3.82e-04	6	102	2	GO:0019767
GeneOntologyMolecularFunction	melanocortin receptor activity	MC2R MC5R	3.82e-04	6	102	2	GO:0004977
GeneOntologyMolecularFunction	IgE binding	FCGR3A FCGR3B	5.34e-04	7	102	2	GO:0019863
GeneOntologyMolecularFunction	IgG receptor activity	FCGR3A FCGR3B	5.34e-04	7	102	2	GO:0019770
GeneOntologyMolecularFunction	IgG binding	FCGR3A FCGR3B	1.38e-03	11	102	2	GO:0019864
GeneOntologyMolecularFunction	complement receptor activity	FPR2 FPR3	2.26e-03	14	102	2	GO:0004875
GeneOntologyMolecularFunction	immunoglobulin receptor activity	FCGR3A FCGR3B	2.26e-03	14	102	2	GO:0019763
GeneOntologyMolecularFunction	neuropeptide receptor activity	MC2R GALR2 TACR2	2.52e-03	53	102	3	GO:0008188
GeneOntologyMolecularFunction	RAGE receptor binding	FPR2 FPR3	2.60e-03	15	102	2	GO:0050786
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9A9 SLC38A3	2.96e-03	16	102	2	GO:0015385
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR2A14 OR1M1 CYSLTR2 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 SPNS2 OR5AS1 OR1S2 FPR2 FPR3 MC2R OR4M1 GPR78 MC5R OR5A1 ACKR4 GRM4 GALR2 OR9G9 OR11H6 OR52E2 OR10D4P FZD4 OR51L1 OR51D1 OR4S1 OR52A4P ADGRG2 CXCR6 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 TACR2 OR52W1 LGR6 OR5L2 CX3CL1 GPR45 ADGRD1	4.58e-27	1395	102	46	GO:0007186
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	9.42e-24	432	102	28	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	7.02e-23	465	102	28	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	2.20e-22	485	102	28	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	1.78e-21	524	102	28	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	5.62e-21	547	102	28	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	2.94e-20	582	102	28	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	8.50e-18	722	102	28	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 SPNS2 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR10D4P FZD4 OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	3.22e-15	1072	102	30	GO:0007600
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	FPR2 MC2R OR4M1 GPR78 MC5R GRM4 GALR2 ADGRG2 ADGRD1	1.24e-05	286	102	9	GO:0007188
GeneOntologyBiologicalProcess	perforin production	FCGR3A FCGR3B	2.42e-05	2	102	2	GO:0035944
GeneOntologyBiologicalProcess	adenylate cyclase-activating G protein-coupled receptor signaling pathway	MC2R OR4M1 GPR78 MC5R GALR2 ADGRG2 ADGRD1	4.60e-05	191	102	7	GO:0007189
GeneOntologyBiologicalProcess	coenzyme A metabolic process	HMGCR ALPI ALPG	2.20e-04	24	102	3	GO:0015936
GeneOntologyCellularComponent	Fc-gamma receptor III complex	FCGR3A FCGR3B	1.43e-04	4	103	2	GO:0033001
MousePheno	decreased circulating hormone level	MC2R OR4M1 CERS6 MBOAT4 B4GALT1 FZD4 KCNH6 TACR2 BSCL2 SLC38A3 ADIPOR2	3.09e-05	551	63	11	MP:0014457
MousePheno	long gestation period	B4GALT1 ALPI ALPG	3.82e-05	15	63	3	MP:0002293
MousePheno	abnormal gestational length	B4GALT1 ALPI ALPG	6.78e-05	18	63	3	MP:0002292
MousePheno	decreased hormone level	MC2R OR4M1 CERS6 MBOAT4 B4GALT1 FZD4 KCNH6 TACR2 BSCL2 SLC38A3 ADIPOR2	1.11e-04	635	63	11	MP:0014455
MousePheno	abnormal small intestine morphology	FPR2 FPR3 IREB2 B4GALT1 SLC22A4 BSCL2	1.91e-04	187	63	6	MP:0000496
MousePheno	abnormal vomeronasal sensory neuron physiology	FPR2 FPR3	1.98e-04	5	63	2	MP:0011678
MousePheno	abnormal vomeronasal organ physiology	FPR2 FPR3	1.98e-04	5	63	2	MP:0013596
Domain	7tm_1	OR2A14 OR1M1 CYSLTR2 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 FPR2 FPR3 MC2R OR4M1 GPR78 MC5R OR5A1 ACKR4 GALR2 OR9G9 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR52A4P CXCR6 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR6Y1 TACR2 OR52W1 LGR6 OR5L2 GPR45	1.82e-29	677	98	38	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR2A14 OR1M1 CYSLTR2 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 FPR2 FPR3 MC2R OR4M1 GPR78 MC5R OR5A1 ACKR4 GALR2 OR9G9 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR52A4P CXCR6 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR6Y1 TACR2 OR52W1 LGR6 OR5L2 GPR45	2.80e-29	685	98	38	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2A14 OR1M1 CYSLTR2 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 FPR2 FPR3 MC2R OR4M1 GPR78 MC5R OR5A1 ACKR4 GALR2 OR9G9 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR52A4P CXCR6 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR6Y1 TACR2 OR52W1 LGR6 OR5L2 GPR45	3.86e-29	691	98	38	PS50262
Domain	GPCR_Rhodpsn	OR2A14 OR1M1 CYSLTR2 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 FPR2 FPR3 MC2R OR4M1 GPR78 MC5R OR5A1 ACKR4 GALR2 OR9G9 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR52A4P CXCR6 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR6Y1 TACR2 OR52W1 LGR6 OR5L2 GPR45	4.07e-29	692	98	38	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR2A14 OR1M1 CYSLTR2 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 FPR2 FPR3 MC2R OR4M1 GPR78 MC5R OR5A1 ACKR4 GALR2 OR9G9 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR52A4P CXCR6 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR6Y1 TACR2 OR52W1 OR5L2 GPR45	2.19e-28	670	98	37	IPR017452
Domain	Olfact_rcpt	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR52A4P OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR6Y1 OR52W1 OR5L2	1.06e-21	393	98	26	IPR000725
Domain	Formyl_pep_2/3_rcpt	FPR2 FPR3	2.73e-05	2	98	2	IPR027347
Domain	Alk_phosphatase	ALPI ALPG	1.62e-04	4	98	2	PF00245
Domain	Alkaline_phosphatase_AS	ALPI ALPG	1.62e-04	4	98	2	IPR018299
Domain	Alkaline_phosphatase	ALPI ALPG	1.62e-04	4	98	2	IPR001952
Domain	alkPPc	ALPI ALPG	1.62e-04	4	98	2	SM00098
Domain	ALKALINE_PHOSPHATASE	ALPI ALPG	1.62e-04	4	98	2	PS00123
Domain	7TM_GPCR_Srsx	OR8D1 MC2R MC5R GALR2 TACR2	3.09e-04	112	98	5	SM01381
Domain	Melcrt_ACTH_rcpt	MC2R MC5R	4.03e-04	6	98	2	IPR001671
Domain	Formyl_rcpt-rel	FPR2 FPR3	1.19e-03	10	98	2	IPR000826
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH1	2.38e-03	14	98	2	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DNAH1	2.38e-03	14	98	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH2 DNAH1	2.38e-03	14	98	2	IPR013602
Domain	DHC_N2	DNAH2 DNAH1	2.38e-03	14	98	2	PF08393
Domain	MT	DNAH2 DNAH1	2.38e-03	14	98	2	PF12777
Domain	AAA_8	DNAH2 DNAH1	2.38e-03	14	98	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH1	2.38e-03	14	98	2	IPR011704
Domain	AAA_5	DNAH2 DNAH1	2.38e-03	14	98	2	PF07728
Domain	DHC_fam	DNAH2 DNAH1	2.74e-03	15	98	2	IPR026983
Domain	Dynein_heavy_dom	DNAH2 DNAH1	2.74e-03	15	98	2	IPR004273
Domain	Dynein_heavy	DNAH2 DNAH1	2.74e-03	15	98	2	PF03028
Domain	Chemokine_rcpt	ACKR4 CXCR6	3.12e-03	16	98	2	IPR000355
Domain	Frizzled/SFRP	SFRP4 FZD4	3.12e-03	16	98	2	IPR015526
Domain	GPCR_2_secretin-like	FZD4 ADGRG2 ADGRD1	3.86e-03	60	98	3	IPR000832
Domain	GPCR_2-like	FZD4 ADGRG2 ADGRD1	3.86e-03	60	98	3	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	FZD4 ADGRG2 ADGRD1	4.04e-03	61	98	3	PS50261
Domain	FRI	SFRP4 FZD4	4.87e-03	20	98	2	SM00063
Domain	-	SFRP4 FZD4	5.36e-03	21	98	2	1.10.2000.10
Domain	DAPIN	NLRP11 NLRP4	5.88e-03	22	98	2	PS50824
Domain	PYRIN	NLRP11 NLRP4	5.88e-03	22	98	2	PF02758
Domain	DAPIN	NLRP11 NLRP4	5.88e-03	22	98	2	IPR004020
Domain	PYRIN	NLRP11 NLRP4	5.88e-03	22	98	2	SM01289
Domain	NACHT	NLRP11 NLRP4	6.42e-03	23	98	2	PS50837
Domain	NACHT_NTPase	NLRP11 NLRP4	6.42e-03	23	98	2	IPR007111
Domain	Frizzled_dom	SFRP4 FZD4	6.98e-03	24	98	2	IPR020067
Domain	FZ	SFRP4 FZD4	6.98e-03	24	98	2	PS50038
Domain	Fz	SFRP4 FZD4	6.98e-03	24	98	2	PF01392
Domain	MFS_1	SPNS2 SLC16A12 SLC22A4	7.74e-03	77	98	3	PF07690
Domain	MFS	SPNS2 SLC16A12 SLC22A4	7.74e-03	77	98	3	IPR011701
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR9G9 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	1.60e-19	417	87	26	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR6Y1 OR52W1 OR5L2	6.56e-18	389	87	24	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 GRM4 OR9G9 OR11H6 OR52E2 OR51L1 OR51D1 OR4S1 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	4.90e-16	636	87	27	M41834
Pathway	WP_GPCRS_PEPTIDE	FPR2 FPR3 MC2R MC5R GALR2 CXCR6 TACR2	2.34e-07	70	87	7	MM15959
Pathway	WP_PEPTIDE_GPCRS	FPR2 FPR3 MC2R MC5R GALR2 CXCR6 TACR2	3.77e-07	75	87	7	M39696
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	FPR2 FPR3 MC2R MC5R ACKR4 GALR2 CXCR6 TACR2 CX3CL1	3.39e-06	197	87	9	M12289
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	FPR2 FPR3 MC2R MC5R ACKR4 GALR2 CXCR6 TACR2 CX3CL1	3.39e-06	197	87	9	MM14970
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	OR8D1 FPR2 FPR3 MC2R MC5R GALR2 OR10D4P GPR45	1.90e-05	186	87	8	MM15994
Pathway	REACTOME_GPCR_LIGAND_BINDING	CYSLTR2 FPR2 FPR3 MC2R MC5R ACKR4 GRM4 GALR2 FZD4 CXCR6 TACR2 CX3CL1	2.59e-05	463	87	12	M507
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	CYSLTR2 FPR2 FPR3 MC2R MC5R ACKR4 GALR2 CXCR6 TACR2 CX3CL1	3.49e-05	330	87	10	M18334
Pathway	WP_GPCRS_NONODORANT	CYSLTR2 MC2R MC5R GRM4 GALR2 FZD4 ADGRG2 CXCR6 TACR2	3.76e-05	266	87	9	MM15843
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	CYSLTR2 FPR2 FPR3 MC2R MC5R ACKR4 GALR2 CXCR6 TACR2 CX3CL1	3.77e-05	333	87	10	MM14963
Pathway	REACTOME_GPCR_LIGAND_BINDING	CYSLTR2 FPR2 FPR3 MC2R MC5R ACKR4 GRM4 GALR2 CXCR6 TACR2 CX3CL1	6.51e-05	430	87	11	MM15160
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	CYSLTR2 FPR2 FPR3 MC2R MC5R ACKR4 GALR2 GPR45	2.00e-04	260	87	8	M39397
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	CYSLTR2 FPR2 FPR3 MC2R MC5R GRM4 GALR2 TACR2	2.71e-04	272	87	8	M13380
Pathway	REACTOME_SIGNALING_BY_GPCR	CYSLTR2 FPR2 FPR3 MC2R MC5R ACKR4 GRM4 GALR2 FZD4 CXCR6 TACR2 CX3CL1 GPR45	3.51e-04	702	87	13	M746
Pathway	REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS	FCGR3A FCGR3B LY6K ALPI ALPG	3.62e-04	99	87	5	MM14624
Pathway	KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPJ_TO_IGG_FCGR_RAC_SIGNALING_PATHWAY	FCGR3A FCGR3B	3.72e-04	5	87	2	M49014
Pathway	REACTOME_SIGNALING_BY_GPCR	CYSLTR2 FPR2 FPR3 MC2R MC5R ACKR4 GRM4 GALR2 CXCR6 TACR2 CX3CL1 GPR45	5.88e-04	646	87	12	MM14962
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR8D1 OR11H6 OR51D1 OR1E3	9.10e-04	70	87	4	MM14984
Pathway	REACTOME_FORMYL_PEPTIDE_RECEPTORS_BIND_FORMYL_PEPTIDES_AND_MANY_OTHER_LIGANDS	FPR2 FPR3	1.03e-03	8	87	2	M27370
Pathway	REACTOME_FORMYL_PEPTIDE_RECEPTORS_BIND_FORMYL_PEPTIDES_AND_MANY_OTHER_LIGANDS	FPR2 FPR3	1.03e-03	8	87	2	MM15110
Pathway	KEGG_MEDICUS_REFERENCE_IGG_FCGR_RAC_SIGNALING_PATHWAY	FCGR3A FCGR3B	1.64e-03	10	87	2	M47727
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR11H6 OR52E2 OR10D4P OR51D1 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	9.43e-25	340	104	23	11875048
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR11H6 OR52E2 OR10D4P OR51D1 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	1.15e-24	343	104	23	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR11H6 OR52E2 OR10D4P OR51D1 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	1.41e-24	346	104	23	14611657
Pubmed	The human olfactory receptor gene family.	OR2A14 OR1M1 OR8D1 OR6S1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR11H6 OR52E2 OR10D4P OR51L1 OR51D1 OR4S1 OR7D2 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	3.93e-24	541	104	26	14983052
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2A14 OR1M1 OR8D1 OR4S2 OR5D18 OR5L1 OR5AS1 OR1S2 OR4M1 OR5A1 OR11H6 OR52E2 OR10D4P OR51D1 OR52D1 OR52N2 OR5C1 OR52E4 OR1E3 OR6Y1 OR52W1 OR5L2	2.86e-23	340	104	22	11802173
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR2A14 OR1M1 OR4S2 OR5D18 OR1S2 OR5A1 OR7D2 OR5L2	3.33e-07	219	104	8	12213199
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR6S1 OR10D4P OR52N2 OR1E3 OR6Y1	2.97e-06	74	104	5	15081110
Pubmed	Resolvin D1 protects the liver from ischemia/reperfusion injury by enhancing M2 macrophage polarization and efferocytosis.	FPR2 FPR3	8.86e-06	2	104	2	27317426
Pubmed	FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.	FCGR3A FCGR3B	8.86e-06	2	104	2	27059607
Pubmed	Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.	FCGR3A FCGR3B	8.86e-06	2	104	2	2521732
Pubmed	FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene.	FCGR3A FCGR3B	8.86e-06	2	104	2	34108956
Pubmed	A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation.	FPR2 FPR3	8.86e-06	2	104	2	23733341
Pubmed	N-formyl peptide receptor 3 (FPR3) departs from the homologous FPR2/ALX receptor with regard to the major processes governing chemoattractant receptor regulation, expression at the cell surface, and phosphorylation.	FPR2 FPR3	8.86e-06	2	104	2	21543323
Pubmed	Single-cell analyses identify dysfunctional CD16+ CD8 T cells in smokers.	FCGR3A FCGR3B	8.86e-06	2	104	2	33163982
Pubmed	Low copy numbers of FCGR3A and FCGR3B associated with Chinese patients with SLE and AASV.	FCGR3A FCGR3B	8.86e-06	2	104	2	28355982
Pubmed	Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes.	FPR2 FPR3	8.86e-06	2	104	2	8198572
Pubmed	The human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential.	FCGR3A FCGR3B	8.86e-06	2	104	2	23770975
Pubmed	Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses.	FPR2 FPR3	8.86e-06	2	104	2	17084101
Pubmed	Association of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.	FCGR3A FCGR3B	8.86e-06	2	104	2	25154742
Pubmed	Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.	FCGR3A FCGR3B	8.86e-06	2	104	2	26494566
Pubmed	Characterization of murine melanocortin receptors mediating adipocyte lipolysis and examination of signalling pathways involved.	MC2R MC5R	8.86e-06	2	104	2	21616121
Pubmed	The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions.	FCGR3A FCGR3B	8.86e-06	2	104	2	7836402
Pubmed	Spatial and temporal patterns of expression of melanocortin type 2 and 5 receptors in the fetal mouse tissues and organs.	MC2R MC5R	8.86e-06	2	104	2	16463171
Pubmed	Resolution of post-lung transplant ischemia-reperfusion injury is modulated via Resolvin D1-FPR2 and Maresin 1-LGR6 signaling.	FPR2 LGR6	8.86e-06	2	104	2	36628837
Pubmed	Strain-specific Loss of Formyl Peptide Receptor 3 in the Murine Vomeronasal and Immune Systems.	FPR2 FPR3	8.86e-06	2	104	2	26957543
Pubmed	Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.	FCGR3A FCGR3B	8.86e-06	2	104	2	22290871
Pubmed	Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.	FCGR3A FCGR3B	8.86e-06	2	104	2	25816339
Pubmed	Fcγ receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis.	FCGR3A FCGR3B	8.86e-06	2	104	2	20980704
Pubmed	A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms.	FCGR3A FCGR3B	8.86e-06	2	104	2	2525780
Pubmed	Nucleotide sequence of a new Fc gamma receptor IIIB allele that codes for a neutrophil antigen.	FCGR3A FCGR3B	8.86e-06	2	104	2	11034564
Pubmed	Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors.	FPR2 FPR3	8.86e-06	2	104	2	9151906
Pubmed	Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.	FCGR3A FCGR3B	8.86e-06	2	104	2	23917248
Pubmed	Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).	FPR2 FPR3	8.86e-06	2	104	2	12172542
Pubmed	Reversal of β-Amyloid-Induced Microglial Toxicity In Vitro by Activation of Fpr2/3.	FPR2 FPR3	8.86e-06	2	104	2	32617132
Pubmed	Evidence for gene recombination in FCGR3 gene variants.	FCGR3A FCGR3B	8.86e-06	2	104	2	19320901
Pubmed	Lipoxin A4 inhibits the production of proinflammatory cytokines induced by β-amyloid in vitro and in vivo.	FPR2 FPR3	8.86e-06	2	104	2	21501589
Pubmed	Evaluation of fractalkine (FKN) and secreted frizzled-related protein 4 (SFRP-4) serum levels in patients with prediabetes and type 2 diabetes.	SFRP4 CX3CL1	8.86e-06	2	104	2	29455547
Pubmed	Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.	FCGR3A FCGR3B	8.86e-06	2	104	2	25966632
Pubmed	FcgammaRIII expression on cultured human keratinocytes and upregulation by interferon-gamma.	FCGR3A FCGR3B	8.86e-06	2	104	2	12445195
Pubmed	The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein.	FCGR3A FCGR3B	8.86e-06	2	104	2	2967436
Pubmed	Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions.	FCGR3A FCGR3B	8.86e-06	2	104	2	2526846
Pubmed	Separate promoters from proximal and medial control regions contribute to the natural killer cell-specific transcription of the human FcgammaRIII-A (CD16-A) receptor gene.	FCGR3A FCGR3B	8.86e-06	2	104	2	8940055
Pubmed	Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis.	FPR2 FPR3	8.86e-06	2	104	2	25512512
Pubmed	The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcgammaRIIIa-48L/R/H polymorphism.	FCGR3A FCGR3B	8.86e-06	2	104	2	20664961
Pubmed	B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.	FCGR3A FCGR3B	8.86e-06	2	104	2	18292508
Pubmed	N-Formylated humanin activates both formyl peptide receptor-like 1 and 2.	FPR2 FPR3	8.86e-06	2	104	2	15465011
Pubmed	A novel rat lipoxin A4 receptor that is conserved in structure and function.	FPR2 FPR3	8.86e-06	2	104	2	12746227
Pubmed	Association of Fcgamma receptor IIa genotype with chronic periodontitis in Caucasians.	FCGR3A FCGR3B	2.65e-05	3	104	2	15152814
Pubmed	Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.	FCGR3A FCGR3B	2.65e-05	3	104	2	25775045
Pubmed	The Fc gamma receptor genotype as a severity factor for chronic periodontitis in Japanese patients.	FCGR3A FCGR3B	2.65e-05	3	104	2	11699473
Pubmed	Fcgamma receptor polymorphisms and their association with periodontal disease: a meta-analysis.	FCGR3A FCGR3B	2.65e-05	3	104	2	20149216
Pubmed	Fc gamma RIIa, IIIa and IIIb polymorphisms in Turkish children susceptible to recurrent infectious diseases.	FCGR3A FCGR3B	2.65e-05	3	104	2	16550341
Pubmed	Associations between FCGR3A polymorphisms and susceptibility to rheumatoid arthritis: a metaanalysis.	FCGR3A FCGR3B	2.65e-05	3	104	2	18843786
Pubmed	Association of the Fc gamma receptor IIA-R/R131 genotype with myasthenia gravis in Dutch patients.	FCGR3A FCGR3B	2.65e-05	3	104	2	14597109
Pubmed	Risk of periodontitis in systemic lupus erythematosus is associated with Fcgamma receptor polymorphisms.	FCGR3A FCGR3B	2.65e-05	3	104	2	12710759
Pubmed	Two gene duplication events in the evolution of the human heat-stable alkaline phosphatases.	ALPI ALPG	2.65e-05	3	104	2	3443302
Pubmed	Cutting edge: intravenous Ig inhibits invariant NKT cell-mediated allergic airway inflammation through FcγRIIIA-dependent mechanisms.	FCGR3A FCGR3B	2.65e-05	3	104	2	21317388
Pubmed	Fc gamma receptor genes as risk markers for localized aggressive periodontitis in African-Americans.	FCGR3A FCGR3B	2.65e-05	3	104	2	12027254
Pubmed	Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5.	MC2R MC5R	2.65e-05	3	104	2	25860801
Pubmed	Defective formyl peptide receptor 2/3 and annexin A1 expressions associated with M2a polarization of blood immune cells in patients with chronic obstructive pulmonary disease.	FPR2 FPR3	2.65e-05	3	104	2	29544524
Pubmed	Opposite effects of the melanocortin-2 (MC2) receptor accessory protein MRAP on MC2 and MC5 receptor dimerization and trafficking.	MC2R MC5R	2.65e-05	3	104	2	19535343
Pubmed	Allelic and copy-number variations of FcγRs affect granulocyte function and susceptibility for autoimmune blistering diseases.	FCGR3A FCGR3B	2.65e-05	3	104	2	26032265
Pubmed	Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.	FPR2 FPR3	2.65e-05	3	104	2	15879124
Pubmed	Association study of copy number variants in CCL3L1, FCGR3A and FCGR3B genes with risk of ankylosing spondylitis in a West Algerian population.	FCGR3A FCGR3B	2.65e-05	3	104	2	31433132
Pubmed	Analysis of Fc gamma RIII (CD16) membrane expression and association with CD3 zeta and Fc epsilon RI-gamma by site-directed mutation.	FCGR3A FCGR3B	2.65e-05	3	104	2	1825220
Pubmed	Genetic polymorphism of Fcγ-receptors IIa, IIIa and IIIb in South Indian patients with generalized aggressive periodontitis.	FCGR3A FCGR3B	2.65e-05	3	104	2	22167032
Pubmed	The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.	FPR2 FPR3	2.65e-05	3	104	2	19234121
Pubmed	Polymorphisms of Immunoglobulin G Fc Receptors in Pediatric Guillain-Barré Syndrome.	FCGR3A FCGR3B	2.65e-05	3	104	2	27064330
Pubmed	Absence of association between the Fc gamma receptor IIIA-176F/V polymorphism and the severity of malaria in Thai.	FCGR3A FCGR3B	2.65e-05	3	104	2	12501257
Pubmed	Polymorphism of Fc gamma RIIa may affect the efficacy of gamma-globulin therapy in Kawasaki disease.	FCGR3A FCGR3B	2.65e-05	3	104	2	16133986
Pubmed	Intestinal Alkaline Phosphatase Regulates Tight Junction Protein Levels.	ALPI ALPG	2.65e-05	3	104	2	27106638
Pubmed	Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties.	FPR2 FPR3	2.65e-05	3	104	2	22859307
Pubmed	Organic pyrophosphates as substrates for human alkaline phosphatases.	ALPI ALPG	2.65e-05	3	104	2	16742561
Pubmed	Identification, cloning, and functional characterization of a murine lipoxin A4 receptor homologue gene.	FPR2 FPR3	2.65e-05	3	104	2	12218158
Pubmed	Drug-induced agranulocytosis: impact of different fcgamma receptor polymorphisms?	FCGR3A FCGR3B	2.65e-05	3	104	2	16160618
Pubmed	Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children.	FCGR3A FCGR3B	2.65e-05	3	104	2	34551786
Pubmed	Susceptibility to Plasmodium falciparum Malaria: Influence of Combined Polymorphisms of IgG3 Gm Allotypes and Fc Gamma Receptors IIA, IIIA, and IIIB.	FCGR3A FCGR3B	2.65e-05	3	104	2	33424858
Pubmed	FcgammaRIIA and FcgammaRIIIB mediate nuclear factor activation through separate signaling pathways in human neutrophils.	FCGR3A FCGR3B	2.65e-05	3	104	2	19342628
Pubmed	Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4.	FPR2 FPR3	2.65e-05	3	104	2	12410796
Pubmed	Effects of disruption of the embryonic alkaline phosphatase gene on preimplantation development of the mouse.	ALPI ALPG	2.65e-05	3	104	2	10767088
Pubmed	Formyl peptide receptor 2 is an emerging modulator of inflammation in the liver.	FPR2 FPR3	2.65e-05	3	104	2	36750693
Pubmed	Expression of melanocortin receptors in human endometrium.	MC2R MC5R	2.65e-05	3	104	2	26223677
Pubmed	The role of fcgamma receptor gene polymorphism in pediatric renal transplant rejections.	FCGR3A FCGR3B	2.65e-05	3	104	2	19100392
Pubmed	Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.	FCGR3A FCGR3B	2.65e-05	3	104	2	28427365
Pubmed	Characterization of two new members of the formyl peptide receptor gene family from 129S6 mice.	FPR2 FPR3	2.65e-05	3	104	2	12459252
Pubmed	MUSEAP, a novel reporter gene for the study of long-term gene expression in immunocompetent mice.	ALPI ALPG	2.65e-05	3	104	2	11722850
Pubmed	Different stabilities of the structurally related receptors for IgE and IgG on the cell surface are determined by length of the stalk region in their alpha-chains.	FCGR3A FCGR3B	2.65e-05	3	104	2	16709862
Pubmed	Formyl peptide receptor-like 2 is expressed and functional in plasmacytoid dendritic cells, tissue-specific macrophage subpopulations, and eosinophils.	FPR2 FPR3	2.65e-05	3	104	2	19342677
Pubmed	Deletion of Annexin A1 in Mice Upregulates the Expression of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in Platelets.	FPR2 FPR3	2.65e-05	3	104	2	36834844
Pubmed	HIV-1 Tat inhibits human natural killer cell function by blocking L-type calcium channels.	FCGR3A FCGR3B	2.65e-05	3	104	2	9743356
Pubmed	Study of common functional genetic polymorphisms of FCGR2A, 3A and 3B genes and the risk for cryptococcosis in HIV-uninfected patients.	FCGR3A FCGR3B	2.65e-05	3	104	2	17710620
Pubmed	Association of rheumatoid factor production with FcgammaRIIIa polymorphism in Taiwanese rheumatoid arthritis.	FCGR3A FCGR3B	2.65e-05	3	104	2	16542359
Pubmed	FCGR2A, FCGR3A, FCGR3B polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis.	FCGR3A FCGR3B	2.65e-05	3	104	2	26314337
Pubmed	Polymorphisms of Fc gamma-receptors RIIa, RIIIa, and RIIIb in patients with adult periodontal diseases.	FCGR3A FCGR3B	2.65e-05	3	104	2	11528518
Pubmed	ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.	FPR2 FPR3	2.65e-05	3	104	2	27207555
Pubmed	Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease.	FCGR3A FCGR3B	2.65e-05	3	104	2	19946017
Pubmed	Fcgamma receptor IIa, IIIa, and IIIb polymorphisms in German patients with systemic lupus erythematosus: association with clinical symptoms.	FCGR3A FCGR3B	2.65e-05	3	104	2	12176802
Pubmed	Molecular cloning and characterization of beta-1,4-galactosyltransferase expressed in mouse testis.	B4GALT1 WDFY3	2.65e-05	3	104	2	9108238
Pubmed	Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ.	FPR2 FPR3	2.65e-05	3	104	2	19497865
Pubmed	Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair.	FPR2 FPR3	2.65e-05	3	104	2	31585047
Interaction	CERS6 interactions	FPR2 CERS6 FZD4 ADGRG2 SLC22A4 BSCL2	3.87e-06	104	81	6	int:CERS6
Interaction	ADGRG2 interactions	INTS1 CERS6 ADGRG2	1.34e-05	12	81	3	int:ADGRG2
Interaction	ATP13A3 interactions	DPY19L1 SPCS1 FPR2 SPPL3 SLC22A4 GPR45	2.71e-05	146	81	6	int:ATP13A3
Interaction	CRELD1 interactions	CACNG1 DPY19L1 SPCS1 SPPL3 CERS6 SLC22A4	5.02e-05	163	81	6	int:CRELD1
Interaction	ART5 interactions	C1orf54 FCGR3B ALPI ALPG	5.24e-05	51	81	4	int:ART5
Interaction	GPRC5C interactions	CACNG1 FPR2 SLC22A4 BSCL2 GPR45	5.95e-05	103	81	5	int:GPRC5C
Interaction	UGT3A2 interactions	C1orf54 HTR3C UGT3A2	6.79e-05	20	81	3	int:UGT3A2
Interaction	ABHD3 interactions	HTR3C SLC22A4 GPR45	9.12e-05	22	81	3	int:ABHD3
Interaction	MFSD8 interactions	CACNG1 FPR2 SLC22A4 BSCL2	9.32e-05	59	81	4	int:MFSD8
Interaction	LY6K interactions	SPPL3 LY6K	9.52e-05	4	81	2	int:LY6K
Interaction	GALR2 interactions	SPPL3 GALR2	9.52e-05	4	81	2	int:GALR2
Interaction	LMBRD2 interactions	FPR2 LAMP5 SLC22A4 BSCL2	1.36e-04	65	81	4	int:LMBRD2
Interaction	AVPR2 interactions	DPY19L1 INTS1 SPPL3 HMGCR CERS6	1.38e-04	123	81	5	int:AVPR2
Interaction	SPNS2 interactions	SPNS2 SPPL3	1.58e-04	5	81	2	int:SPNS2
Cytoband	11p15.4	OR52E2 OR51L1 OR51D1 OR52A4P OR52D1 OR52N2 OR52E4 OR52W1	2.03e-08	200	104	8	11p15.4
Cytoband	11q11	OR4S2 OR5D18 OR5L1 OR9G9 OR5L2	7.70e-08	47	104	5	11q11
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR5D18 OR5L1 OR5AS1 OR1S2 OR5A1 BSCL2 OR5L2	1.45e-05	345	104	7	chr11q12
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR52E2 OR51L1 OR51D1 OR52A4P OR52D1 OR52N2 OR52E4 OR52W1	4.53e-05	564	104	8	chr11p15
Cytoband	18p11.2	MC2R MC5R	1.81e-04	9	104	2	18p11.2
Cytoband	19q13.3-q13.4	FPR2 FPR3	3.90e-04	13	104	2	19q13.3-q13.4
Cytoband	1q23	FCGR3A FCGR3B	1.25e-03	23	104	2	1q23
GeneFamily	Olfactory receptors, family 52	OR52E2 OR52A4P OR52D1 OR52N2 OR52E4 OR52W1	1.42e-07	49	89	6	165
GeneFamily	Olfactory receptors, family 5	OR5D18 OR5L1 OR5AS1 OR5A1 OR5C1 OR5L2	1.89e-05	112	89	6	152
GeneFamily	Formyl peptide receptors	FPR2 FPR3	7.17e-05	3	89	2	198
GeneFamily	Alkaline phosphatases	ALPI ALPG	1.43e-04	4	89	2	1072
GeneFamily	Melanocortin receptors	MC2R MC5R	2.37e-04	5	89	2	236
GeneFamily	Leukotriene receptors	CYSLTR2 FPR2	3.55e-04	6	89	2	204
GeneFamily	Olfactory receptors, family 1	OR1M1 OR1S2 OR1E3	9.99e-04	40	89	3	147
GeneFamily	Dyneins, axonemal	DNAH2 DNAH1	3.11e-03	17	89	2	536
GeneFamily	NLR family	NLRP11 NLRP4	6.68e-03	25	89	2	666
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP11 NLRP4	6.68e-03	25	89	2	994
GeneFamily	G protein-coupled receptors, Class A orphans	GPR78 LGR6 GPR45	6.72e-03	78	89	3	262
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC28A3 GRM4 UGT3A2 LY6K NLRP4 ALPG	2.89e-06	176	100	6	d5cee483d2a60f82fdc67ad447b589d022fe8c97
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor-Germ\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC28A3 GRM4 UGT3A2 LY6K NLRP4 ALPG	2.89e-06	176	100	6	eea554ea75580f8dd5fefb57e7f33441ab86b884
ToppCell	COVID-19-kidney-Epithelial_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	SLC9A9 OR5AS1 FPR3 CXCR6 ADGRD1	7.63e-06	120	100	5	e17c85d41c781a29dec7e03a8b0637dccb4346bc
Drug	Fnllp	FPR2 FPR3 FCGR3A FCGR3B	3.82e-07	14	103	4	CID000119508
Drug	Bplplp	FPR2 FPR3 FCGR3A FCGR3B	6.40e-06	27	103	4	CID000125628
Disease	level of low affinity immunoglobulin gamma Fc region receptor III-A in blood serum	FCGR3A FCGR3B	1.03e-05	2	95	2	OBA_2040305
Disease	Lupus Vasculitis, Central Nervous System	FCGR3A FCGR3B	3.07e-05	3	95	2	C0752332
Disease	Lupus Meningoencephalitis	FCGR3A FCGR3B	3.07e-05	3	95	2	C0752334
Disease	Neuropsychiatric Systemic Lupus Erythematosus	FCGR3A FCGR3B	3.07e-05	3	95	2	C0752335
Disease	beta-1,4-galactosyltransferase 1 measurement	FPR3 B4GALT1	1.02e-04	5	95	2	EFO_0801409
Disease	low affinity immunoglobulin gamma Fc region receptor II-a/b measurement	FCGR3A FCGR3B	2.13e-04	7	95	2	EFO_0008211
Disease	plexin-B2 measurement	FCGR3A FCGR3B	3.64e-04	9	95	2	EFO_0021867
Disease	low affinity immunoglobulin gamma Fc region receptor III-B measurement	FCGR3A FCGR3B	9.10e-04	14	95	2	EFO_0008212
Disease	hyperinsulinism (biomarker_via_orthology)	IREB2 ADIPOR2	1.05e-03	15	95	2	DOID:2018 (biomarker_via_orthology)
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	FCGR3A FCGR3B	1.35e-03	17	95	2	EFO_0021969
Disease	asthma (is_implicated_in)	CYSLTR2 HMGCR FCGR3A TACR2	1.69e-03	157	95	4	DOID:2841 (is_implicated_in)
Disease	N-glycan measurement	SLC9A9 B4GALT1	2.27e-03	22	95	2	EFO_0004999
Disease	hip bone mineral density, fat body mass	MC2R MC5R	2.27e-03	22	95	2	EFO_0005409, EFO_0007702
Disease	low affinity immunoglobulin gamma Fc region receptor II-b measurement	FCGR3A FCGR3B	2.93e-03	25	95	2	EFO_0021970

Protein segments in the cluster

Peptide	Gene	Start	Entry
YTCFVFSDVDLIPMN	B4GALT1	241	P15291
LPRFSTMPFIYCNIN	COL4A6	1516	Q14031
FLQFSKVFLPCMYLV	CXCR6	26	O00574
PCQVMAVLLHYFFLS	ADGRD1	631	Q6QNK2
AGIFLCYATTFLMIA	GRM4	631	Q14833
VGYFCVIFLLNVSMF	ADGRG2	791	Q8IZP9
MRVTSICNLDIFYFP	HTR3C	156	Q8WXA8
PCPAFLMFENAAYLA	FAM187A	31	A6NFU0
ATAFYRAQPIIEFMC	AGO4	211	Q9HCK5
SMFYAFAGLCILVSV	CACNG1	141	Q06432
CLGIFYMFRPNISFV	ADIPOR2	161	Q86V24
YCVFLDNFNISPMLF	PGBD4	326	Q96DM1
GICFEYFNIAMIIPQ	RAD18	26	Q9NS91
IANMCPEYGAILSFF	IREB2	371	P48200
LAVMAYDRFVAICNP	OR5D18	116	Q8NGL1
FCYSSVITPKMLVNF	OR8D1	71	Q8WZ84
SCLNPILYVFMGASF	ACKR4	296	Q9NPB9
AIPFCAMYLVALVGN	OR52D1	31	Q9H346
FPFCAVYMIALIGNF	OR52E2	31	Q8NGJ4
FPFCIVYLIAIVGNM	OR52E4	31	Q8NGH9
ISFFPCIMQTFLYLA	OR2A14	91	Q96R47
ICYTFNSMIIFGPFL	OR11H6	216	Q8NGC7
FVAICFPLRYTVIMN	OR10D4P	121	Q8NGN7
SVPYAVCLVQMFFVH	OR52W1	96	Q6IF63
YCVIAAVKIFPRFFM	LY6K	66	Q17RY6
SIAAAFLPTFMYCLG	INTS1	2116	Q8N201
FPCSFEFNENFLIML	MTMR9	411	Q96QG7
YCPVAFLSFASMLGL	LGR6	786	Q9HBX8
FCTAIAFLMAVPNYL	NLRP11	456	P59045
AFFNSCLNPMLYVFV	FPR2	291	P25090
VLANYFVFMTFFPAC	HMGCR	201	P04035
AFFNSCLNPILYVFM	FPR3	291	P25089
YGAAVLFLLMCTFAL	KCNH6	396	Q9H252
GLLMAVRQDLYCFPF	DCAF4L1	381	Q3SXM0
AFPLCFMYALATLGN	OR51D1	41	Q8NGF3
ILFCLAYLVAFMGNV	OR51L1	31	Q8NGJ5
FHLPEIYFDACLFQM	OR52A4P	91	A6NMU1
ISVVCFIALLMSYAF	OR4M1	206	Q8NGD0
PMYFFLSQLSFADIC	OR4S1	56	Q8NGB4
TVCLSNLFKSPMYFF	OR4S2	46	Q8NH73
PMYFFLSNLSFIDIC	OR5A1	61	Q8NGJ0
ACFYVAVIFILNGLM	DPY19L1	156	Q2PZI1
TCLMAEFAAKFIVPY	LAMP5	56	Q9UJQ1
LAIFYCLFEMQDPAF	NLRP4	551	Q96MN2
RNVLAAACPYFKSMF	KBTBD7	86	Q8WVZ9
LPFCFMYIIAVVGNC	OR52N2	31	Q8NGI0
IPYTACALQMFVFAG	OR5C1	96	Q8NGR4
FLMYFLLASNVICPA	OR9G9	196	P0C7N8
AIATFLICFAPYVMT	GPR78	246	Q96P69
PFFIIYCRALNSMGQ	DSG1	121	Q02413
VAVFFAPFGVMLCAY	GPR45	201	Q9Y5Y3
SISPYGCALQMFFFA	OR5AS1	91	Q8N127
FVAICHPLNYTTFMR	OR1S2	136	Q8NGQ3
FVAHVMAFAACLEPY	ALPI	476	P09923
FIAHVMAFAACLEPY	ALPG	476	P10696
RLQTPMYFFLGNLSC	OR6S1	56	Q8NH40
SSQLQFFLCSVYVPM	FZD4	91	Q9ULV1
AMDICTFVFSYLLPV	GALR2	186	O43603
LFFCVSDLANVDPMY	DNAH1	3456	Q9P2D7
NDPAAFMAAFYGCLL	DIP2C	391	Q9Y2E4
FMAAFYGCLLAEVVP	DIP2C	396	Q9Y2E4
EDLYLAFPLAFCIFM	CERS6	36	Q6ZMG9
GYQVSFCLVMVLLFA	FCGR3B	206	O75015
PFALLFNYLCIMDSF	MBOAT4	21	Q96T53
GAAIFCVAVFSLYLM	MAN2A2	11	P49641
ILTFAENPFVVSMYC	MAST4	621	O15021
NLHSPMYFFVCSLAV	MC5R	66	P33032
GYQVSFCLVMVLLFA	FCGR3A	206	P08637
LLYNFPMTCAFIGVA	BSCL2	226	Q96G97
CLLAAAFLSYMGPFL	DNAH2	3311	Q9P225
CTFFAVGYMLLPLFA	SLC22A4	236	Q9H015
PCLGQTLYQHVMFVF	CH25H	86	O95992
CYFQNLFPITAMFVS	TACR2	106	P21452
RNVLAAACPYFKSMF	KBTBD6	86	Q86V97
SIPFADCLAQMYFHL	OR1E3	91	Q8WZA6
PEQETLLFSLFFCMY	OR1M1	21	Q8NGA1
ECMAQLYLFSIFAIA	OR8G3P	96	P0DMU2
MVALFSNCPVAYQIL	USP9X	2391	Q93008
TAYTIPIMAFAFVCH	SLC38A3	286	Q99624
LPQVFLCAYMAAFNS	SFXN4	136	Q6P4A7
LAENVIFCYMGLALF	SLC9A9	371	Q8IVB4
SASFEALAIYFPCMN	RIMS4	11	Q9H426
LFMAYGCSPLFVYLV	SLC16A12	291	Q6ZSM3
AVMAYDRFVAICNPL	OR5L1	116	Q8NGL2
VFICSFMVAAPIFGY	SPNS2	146	Q8IVW8
DCLTQVYFSMFFPIL	OR7D2	96	Q96RA2
AGYLVMVISACVLNF	SLC28A3	111	Q9HAS3
AIMAFDRYVAICNPL	OR6Y1	121	Q8NGX8
AVMAYDRFVAICNPL	OR5L2	116	Q8NGL0
QAPMYFFICSLAISD	MC2R	56	Q01718
MCNAVIDPFIYAFRS	MC2R	266	Q01718
PLLLSCAFVQVGMYF	C1orf54	116	Q8WWF1
MNYIALVVGCLLPFF	CYSLTR2	201	Q9NS75
EMLEFVVFSLNYIPC	WDFY3	446	Q8IZQ1
LQLNNPYLCVMFAFL	MIOS	581	Q9NXC5
QFFGFTPQTCMLRIY	MIS12	11	Q9H081
YMFFPSVVLSNCLTR	REV3L	796	O60673
ATIAFAFLLLPMCQY	SPPL3	106	Q8TCT6
AVLRFFLCAMYAPIC	SFRP4	71	Q6FHJ7
PRDFASYMLGIFICN	SIDT1	706	Q9NXL6
MPLESAVNVVDCFFY	TBC1D8	676	O95759
LDYVNSCFPFFICML	TTC41P	96	Q6P2S7
VYIVMAGFAFSCLLT	SPCS1	116	Q9Y6A9
YAVFLALITVMCNDF	S100A2	76	P29034
MVIVETFDYCPFLIA	UGT3A2	141	Q3SY77
LLFCLGVAMFTYQSL	CX3CL1	351	P78423
CMAALIFPIGFYINE	MOSMO	111	Q8NHV5