Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanylate cyclase activity

NPR1 NPR2 GUCY1B2 GUCY2D

3.79e-0810754GO:0004383
GeneOntologyMolecularFunctioncyclase activity

NPR1 NPR2 GUCY1B2 GUCY2D

1.84e-0624754GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

NPR1 NPR2 GUCY1B2 GUCY2D

2.19e-0625754GO:0016849
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRG2 ANO5 TTYH3 GABRA4

3.71e-0550754GO:0099095
GeneOntologyMolecularFunctionadenylate cyclase activity

NPR1 NPR2 GUCY2D

3.99e-0518753GO:0004016
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH5 DYNC1H1

3.99e-0518753GO:0008569
GeneOntologyMolecularFunctionnatriuretic peptide receptor activity

NPR1 NPR2

4.17e-053752GO:0016941
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC25A24 GABRG2 ANO5 TTYH3 SLC12A5 GABRA4

4.46e-05171756GO:0015103
GeneOntologyMolecularFunctionpeptide hormone binding

NPR1 NPR2 IGF1R PIK3R1

5.41e-0555754GO:0017046
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

GABRG2 ANO5 TTYH3 SLC12A5 GABRA4

1.08e-04125755GO:0015108
GeneOntologyMolecularFunctioninsulin binding

IGF1R PIK3R1

1.38e-045752GO:0043559
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DNAH5 DYNC1H1

1.56e-0428753GO:0051959
GeneOntologyMolecularFunctioninsulin receptor binding

SNX4 IGF1R PIK3R1

1.92e-0430753GO:0005158
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA3 DNAH10 DHX35 CHD4 ABCD1 HSP90AB2P DNAH5 DYNC1H1

2.46e-04441758GO:0016887
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GABRG2 ANO5 TTYH3 SLC12A5 GABRA4

2.61e-04151755GO:0008509
GeneOntologyMolecularFunctiontransporter activity

SLC25A24 GABRG2 ABCA3 IGF1R PKD1L1 SLCO1B3 GRIA3 ANO5 TTYH3 ABCD1 AP4M1 SLC47A2 SLC12A5 GABRA4

2.78e-0412897514GO:0005215
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TGFBR1 NPR1 NPR2 BMX IGF1R ERN1 PIK3R1 GUCY2D KDR TEC

3.08e-047097510GO:0016773
GeneOntologyMolecularFunctionchloride channel activity

GABRG2 ANO5 TTYH3 GABRA4

3.09e-0486754GO:0005254
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH10 DNAH5 DYNC1H1

3.61e-0437753GO:0045505
GeneOntologyMolecularFunctionprotein kinase activity

TGFBR1 NPR1 NPR2 BMX IGF1R ERN1 GUCY2D KDR TEC

4.04e-04600759GO:0004672
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC25A24 GABRG2 ABCA3 PKD1L1 SLCO1B3 GRIA3 ANO5 TTYH3 ABCD1 AP4M1 SLC47A2 SLC12A5 GABRA4

4.13e-0411807513GO:0022857
GeneOntologyMolecularFunctionkinase activity

TGFBR1 NPR1 NPR2 BMX IGF1R ERN1 PIK3R1 GUCY2D KDR TEC

5.55e-047647510GO:0016301
GeneOntologyMolecularFunctionhormone binding

NPR1 NPR2 IGF1R PIK3R1

6.13e-04103754GO:0042562
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRG2 ANO5 TTYH3 GABRA4

6.13e-04103754GO:0005253
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TGFBR1 NPR1 NPR2 BMX IGF1R ERN1 PIK3R1 GUCY2D POLRMT KDR TEC

7.22e-049387511GO:0016772
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRG2 GABRA4

7.49e-0411752GO:0008503
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRG2 GRIA3 ANO5 TTYH3 GABRA4

7.99e-04193755GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GABRG2 GRIA3 ANO5 TTYH3 GABRA4

8.76e-04197755GO:0022834
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GABRG2 GRIA3 GABRA4

1.29e-0357753GO:1904315
GeneOntologyMolecularFunctioninsulin receptor substrate binding

IGF1R PIK3R1

1.42e-0315752GO:0043560
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GABRG2 GRIA3 GABRA4

1.49e-0360753GO:0099529
GeneOntologyMolecularFunctionplatelet-derived growth factor receptor binding

ERN1 PIK3R1

1.83e-0317752GO:0005161
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRG2 GRIA3 GABRA4

1.88e-0365753GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRG2 GRIA3 GABRA4

1.88e-0365753GO:0022824
GeneOntologyMolecularFunctionpeptide receptor activity

NPR1 NPR2 GUCY2D TACR1

1.91e-03140754GO:0001653
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRG2 GABRA4

2.05e-0318752GO:0022851
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC25A24 GABRG2 PKD1L1 GRIA3 ANO5 TTYH3 SLC47A2 SLC12A5 GABRA4

2.09e-03758759GO:0015318
GeneOntologyMolecularFunctionATP-dependent activity

ABCA3 DNAH10 DHX35 CHD4 ABCD1 HSP90AB2P DNAH5 DYNC1H1

2.11e-03614758GO:0140657
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

BMX IGF1R KDR TEC

2.17e-03145754GO:0004713
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRG2 GABRA4

2.28e-0319752GO:0004890
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH10 DNAH5 DYNC1H1

2.33e-0370753GO:0003777
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

ANO5 TTYH3

2.53e-0320752GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

ANO5 TTYH3

2.53e-0320752GO:0005229
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GABRG2 GRIA3 GABRA4

2.83e-0375753GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRG2 GRIA3 GABRA4

3.05e-0377753GO:0005230
GeneOntologyMolecularFunctionGABA receptor activity

GABRG2 GABRA4

3.06e-0322752GO:0016917
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC25A24 ABCD1

3.35e-0323752GO:0005346
GeneOntologyMolecularFunctionchannel activity

GABRG2 PKD1L1 GRIA3 ANO5 TTYH3 SLC12A5 GABRA4

3.54e-03525757GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRG2 PKD1L1 GRIA3 ANO5 TTYH3 SLC12A5 GABRA4

3.58e-03526757GO:0022803
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

TGFBR1 IGF1R KDR

4.03e-0385753GO:0019199
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC25A24 ABCD1

4.27e-0326752GO:0000295
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC25A24 ABCD1

5.29e-0329752GO:0015216
GeneOntologyMolecularFunctionamide binding

NPR1 NPR2 IGF1R PIK3R1 GRIA3

5.35e-03299755GO:0033218
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRG2 GRIA3 GABRA4

6.34e-03100753GO:0030594
GeneOntologyMolecularFunctionlipid transporter activity

ABCA3 SLCO1B3 ANO5 ABCD1

6.36e-03196754GO:0005319
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

SLC25A24 ABCD1

6.82e-0333752GO:0015215
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCA3 SLC47A2

7.22e-0334752GO:0042910
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRG2 PKD1L1 GRIA3 ANO5 TTYH3 GABRA4

7.56e-03459756GO:0005216
GeneOntologyMolecularFunctionlyase activity

NPR1 NPR2 GUCY1B2 GUCY2D

8.34e-03212754GO:0016829
GeneOntologyMolecularFunctiongated channel activity

GABRG2 GRIA3 ANO5 TTYH3 GABRA4

8.44e-03334755GO:0022836
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCA3 DNAH10 DHX35 CHD4 ABCD1 HSP90AB2P DNAH5 DYNC1H1

8.47e-03775758GO:0017111
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC25A24 ABCA3 SLCO1B3 ABCD1 SLC47A2 SLC12A5

9.05e-03477756GO:0022804
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

MINDY3 USP45 EIF3F

9.08e-03114753GO:0004843
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC25A24 ABCD1

9.43e-0339752GO:0015605
GeneOntologyBiologicalProcesschloride transmembrane transport

GABRG2 ANO5 TTYH3 PCYOX1 SLC12A5 GABRA4

3.88e-06112776GO:1902476
GeneOntologyBiologicalProcesscellular response to topologically incorrect protein

ERN1 WFS1 PIK3R1 DNAJC3 DNAJB14 ERLEC1

4.76e-06116776GO:0035967
GeneOntologyBiologicalProcesschloride transport

GABRG2 ANO5 TTYH3 PCYOX1 SLC12A5 GABRA4

8.39e-06128776GO:0006821
GeneOntologyBiologicalProcesscGMP biosynthetic process

NPR1 NPR2 GUCY2D

1.07e-0512773GO:0006182
GeneOntologyBiologicalProcessreceptor guanylyl cyclase signaling pathway

NPR1 NPR2 GUCY2D

1.07e-0512773GO:0007168
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

GABRG2 ANO5 TTYH3 PCYOX1 SLC12A5 GABRA4

1.09e-05134776GO:0098661
GeneOntologyBiologicalProcesscGMP-mediated signaling

NPR1 NPR2 GUCY1B2 GUCY2D

1.48e-0540774GO:0019934
GeneOntologyBiologicalProcessendoplasmic reticulum unfolded protein response

ERN1 WFS1 PIK3R1 DNAJC3 ERLEC1

1.65e-0585775GO:0030968
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

GABRG2 ANO5 TTYH3 PCYOX1 SLC12A5 GABRA4

2.32e-05153776GO:0098656
GeneOntologyBiologicalProcesscellular response to unfolded protein

ERN1 WFS1 PIK3R1 DNAJC3 ERLEC1

3.63e-05100775GO:0034620
GeneOntologyBiologicalProcessresponse to topologically incorrect protein

ERN1 WFS1 PIK3R1 DNAJC3 DNAJB14 ERLEC1

3.67e-05166776GO:0035966
GeneOntologyBiologicalProcesscGMP metabolic process

NPR1 NPR2 GUCY2D

4.64e-0519773GO:0046068
GeneOntologyBiologicalProcessinorganic anion transport

GABRG2 ANO5 TTYH3 PCYOX1 SLC12A5 GABRA4

5.77e-05180776GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

GABRG2 ANO5 TTYH3 PCYOX1 SLC12A5 GABRA4

6.32e-05183776GO:0006820
GeneOntologyBiologicalProcesscyclic nucleotide biosynthetic process

NPR1 NPR2 GUCY2D

8.40e-0523773GO:0009190
GeneOntologyBiologicalProcessresponse to unfolded protein

ERN1 WFS1 PIK3R1 DNAJC3 ERLEC1

2.32e-04148775GO:0006986
GeneOntologyBiologicalProcessregulation of endoplasmic reticulum unfolded protein response

ERN1 WFS1 PIK3R1

2.75e-0434773GO:1900101
GeneOntologyCellularComponentreceptor complex

TGFBR1 GABRG2 TRBV27 NPR1 IGF1R GRIA3 KDR ITGAD CR2 IL18R1 GABRA4

8.83e-065817711GO:0043235
GeneOntologyCellularComponentdynein complex

SNX4 DNAH10 DNAH5 DYNC1H1

4.68e-0554774GO:0030286
GeneOntologyCellularComponentmembrane protein complex

TGFBR1 GABRG2 TRBV27 SNX4 IGF1R ERN1 PIK3R1 PKD1L1 GRIA3 TTYH3 DENND5A AP4M1 ITGAD IL18R1 GABRA4

3.24e-0414987715GO:0098796
MousePhenoincreased circulating insulin-like growth factor I level

WFS1 PIK3R1 DHTKD1

1.21e-0511603MP:0004702
DomainPkinase_Tyr

NPR1 NPR2 BMX IGF1R GUCY2D KDR TEC

8.55e-07129757PF07714
DomainGUANYLATE_CYCLASE_1

NPR1 NPR2 GUCY1B2 GUCY2D

8.88e-0719754PS00452
DomainGuanylate_cyc

NPR1 NPR2 GUCY1B2 GUCY2D

8.88e-0719754PF00211
DomainGUANYLATE_CYCLASE_2

NPR1 NPR2 GUCY1B2 GUCY2D

8.88e-0719754PS50125
DomainA/G_cyclase

NPR1 NPR2 GUCY1B2 GUCY2D

8.88e-0719754IPR001054
DomainCYCc

NPR1 NPR2 GUCY1B2 GUCY2D

8.88e-0719754SM00044
DomainSer-Thr/Tyr_kinase_cat_dom

NPR1 NPR2 BMX IGF1R GUCY2D KDR TEC

1.35e-06138757IPR001245
DomainDHC_N1

DNAH10 DNAH5 DYNC1H1

3.43e-068753PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH5 DYNC1H1

3.43e-068753IPR013594
DomainANF_lig-bd_rcpt

NPR1 NPR2 GUCY2D GRIA3

1.43e-0537754IPR001828
DomainANF_receptor

NPR1 NPR2 GUCY2D GRIA3

1.43e-0537754PF01094
DomainPeripla_BP_I

NPR1 NPR2 GUCY2D GRIA3

1.77e-0539754IPR028082
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH5 DYNC1H1

2.19e-0514753IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH5 DYNC1H1

2.19e-0514753IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH5 DYNC1H1

2.19e-0514753IPR013602
DomainDHC_N2

DNAH10 DNAH5 DYNC1H1

2.19e-0514753PF08393
DomainMT

DNAH10 DNAH5 DYNC1H1

2.19e-0514753PF12777
DomainAAA_8

DNAH10 DNAH5 DYNC1H1

2.19e-0514753PF12780
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH5 DYNC1H1

2.19e-0514753IPR011704
DomainAAA_5

DNAH10 DNAH5 DYNC1H1

2.19e-0514753PF07728
DomainDHC_fam

DNAH10 DNAH5 DYNC1H1

2.73e-0515753IPR026983
DomainDynein_heavy_dom

DNAH10 DNAH5 DYNC1H1

2.73e-0515753IPR004273
DomainDynein_heavy

DNAH10 DNAH5 DYNC1H1

2.73e-0515753PF03028
DomainA/G_cyclase_CS

NPR1 NPR2 GUCY2D

4.06e-0517753IPR018297
DomainANF_RECEPTORS

NPR1 NPR2

4.76e-053752PS00458
DomainANPR/GUC

NPR1 NPR2

4.76e-053752IPR001170
DomainNucleotide_cyclase

NPR1 NPR2 GUCY2D

4.86e-0518753IPR029787
Domain-

NPR1 NPR2 GUCY2D

4.86e-05187533.30.70.1230
DomainQuinoprotein_ADH-like_supfam

NWD1 ERN1 AHCTF1 EML6

6.05e-0553754IPR011047
DomainPLAT

LOXHD1 PKD1L1 DENND5A

7.85e-0521753PS50095
Domain-

LOXHD1 PKD1L1 DENND5A

7.85e-05217532.60.60.20
DomainPLAT

LOXHD1 PKD1L1 DENND5A

7.85e-0521753PF01477
DomainPLAT/LH2_dom

LOXHD1 PKD1L1 DENND5A

7.85e-0521753IPR001024
DomainProt_kinase_dom

TGFBR1 NPR1 NPR2 BMX IGF1R ERN1 GUCY2D KDR TEC

1.46e-04489759IPR000719
DomainPROTEIN_KINASE_DOM

TGFBR1 NPR1 NPR2 BMX IGF1R ERN1 GUCY2D KDR TEC

1.55e-04493759PS50011
DomainHNOB_dom_associated

GUCY1B2 GUCY2D

2.36e-046752IPR011645
DomainHNOBA

GUCY1B2 GUCY2D

2.36e-046752PF07701
DomainAAA+_ATPase

ABCA3 DNAH10 ABCD1 DNAH5 DYNC1H1

2.84e-04144755IPR003593
DomainAAA

ABCA3 DNAH10 ABCD1 DNAH5 DYNC1H1

2.84e-04144755SM00382
DomainKinase-like_dom

TGFBR1 NPR1 NPR2 BMX IGF1R ERN1 GUCY2D KDR TEC

3.12e-04542759IPR011009
DomainTyrKc

BMX IGF1R KDR TEC

4.33e-0488754SM00219
DomainTyr_kinase_cat_dom

BMX IGF1R KDR TEC

4.33e-0488754IPR020635
DomainBTK

BMX TEC

5.62e-049752SM00107
DomainZnf_Btk_motif

BMX TEC

5.62e-049752IPR001562
DomainBTK

BMX TEC

5.62e-049752PF00779
DomainZF_BTK

BMX TEC

5.62e-049752PS51113
DomainPROTEIN_KINASE_TYR

BMX IGF1R KDR TEC

6.27e-0497754PS00109
DomainTyr_kinase_AS

BMX IGF1R KDR TEC

6.27e-0497754IPR008266
DomainFN3

FLNC IGF1R TNN CDON MYBPC2

8.90e-04185755SM00060
DomainFN3_dom

FLNC IGF1R TNN CDON MYBPC2

1.53e-03209755IPR003961
DomainLH2

LOXHD1 PKD1L1

2.34e-0318752SM00308
DomainApc4_WD40_dom

NWD1 EML6

2.88e-0320752IPR024977
DomainANAPC4_WD40

NWD1 EML6

2.88e-0320752PF12894
DomainGABAA/Glycine_rcpt

GABRG2 GABRA4

3.81e-0323752IPR006028
PathwayWP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION

GABRG2 PIK3R1 SLC12A5 GABRA4

1.84e-0538594M39854
Pubmed

Cardiac fibrosis in end-stage human heart failure and the cardiac natriuretic peptide guanylyl cyclase system: regulation and therapeutic implications.

NPR1 NPR2 GUCY2D

1.09e-08378325117468
Pubmed

The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.

NPR1 NPR2 GUCY1B2 GUCY2D

2.01e-072378417954614
Pubmed

Region and layer-specific expression of GABAA receptor isoforms and KCC2 in developing cortex.

GABRG2 SLC12A5 GABRA4

1.77e-061178338894703
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH5 DYNC1H1

3.88e-06147839373155
Pubmed

The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate.

NPR1 NPR2

4.97e-06278230696704
Pubmed

Chimeric natriuretic peptide ACNP stimulates both natriuretic peptide receptors, the NPRA and NPRB.

NPR1 NPR2

4.97e-06278223186809
Pubmed

Association between GABA(A) receptor subunit polymorphisms and autism spectrum disorder (ASD).

GABRG2 GABRA4

4.97e-06278226239769
Pubmed

ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding.

NPR1 NPR2

4.97e-06278221828054
Pubmed

Porcine natriuretic peptide type B (pNPPB) maintains mouse oocyte meiotic arrest via natriuretic peptide receptor 2 (NPR2) in cumulus cells.

NPR1 NPR2

4.97e-06278224615855
Pubmed

Vasonatrin peptide stimulates both of the natriuretic peptide receptors, NPRA and NPRB.

NPR1 NPR2

4.97e-06278224699414
Pubmed

Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte.

NPR1 NPR2

4.97e-06278222133375
Pubmed

Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain.

NPR1 NPR2

4.97e-06278222949736
Pubmed

Evolving Models of Pavlovian Conditioning: Cerebellar Cortical Dynamics in Awake Behaving Mice.

GABRG2 SLC12A5

4.97e-06278226655909
Pubmed

Enhanced expression of natriuretic peptide receptor A and B in neutrophils of culprit lesions in patients with acute myocardial infarction.

NPR1 NPR2

4.97e-06278228765884
Pubmed

ATP-independent activation of natriuretic peptide receptors.

NPR1 NPR2

4.97e-06278215911610
Pubmed

IGF-I: a mitogen also involved in differentiation processes in mammalian cells.

IGF1R PIK3R1

4.97e-0627828697095
Pubmed

Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.

NPR1 NPR2

4.97e-06278217848634
Pubmed

Insulin-like growth factor receptor I (IGF-IR) and vascular endothelial growth factor receptor 2 (VEGFR-2) are expressed on the circulating epithelial tumor cells of breast cancer patients.

IGF1R KDR

4.97e-06278223418605
Pubmed

Relationship between SLCO1B3 and ABCA3 polymorphisms and imatinib response in chronic myeloid leukemia patients.

ABCA3 SLCO1B3

4.97e-06278225056761
Pubmed

Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B.

NPR1 NPR2

4.97e-06278220977274
Pubmed

The indolocarbazole, Gö6976, inhibits guanylyl cyclase-A and -B.

NPR1 NPR2

4.97e-06278221366551
Pubmed

Interaction of p85 subunit of PI 3-kinase with insulin and IGF-1 receptors analysed by using the two-hybrid system.

IGF1R PIK3R1

4.97e-0627827589433
Pubmed

ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation.

ERCC8 IGF1R AHCTF1 DHX35

9.70e-065978434108663
Pubmed

Reciprocal feedback regulation of insulin receptor and insulin receptor substrate tyrosine phosphorylation by phosphoinositide 3-kinase in primary adipocytes.

IGF1R PIK3R1

1.49e-05378212220227
Pubmed

Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between αVβ3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesis.

IGF1R KDR

1.49e-05378223331867
Pubmed

Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases.

BMX TEC

1.49e-05378211013262
Pubmed

A sensitive method for determining the phosphorylation status of natriuretic peptide receptors: cGK-Ialpha does not regulate NPR-A.

NPR1 NPR2

1.49e-05378216430226
Pubmed

Skeletal muscle derived Musclin protects the heart during pathological overload.

NPR1 NPR2

1.49e-05378235013221
Pubmed

Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis.

ERN1 KDR

1.49e-05378223529610
Pubmed

Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase.

TGFBR1 PIK3R1

1.49e-05378215657037
Pubmed

Interaction of the molecular weight 85K regulatory subunit of the phosphatidylinositol 3-kinase with the insulin receptor and the insulin-like growth factor-1 (IGF- I) receptor: comparative study using the yeast two-hybrid system.

IGF1R PIK3R1

1.49e-0537828603569
Pubmed

The Tec Kinase-Regulated Phosphoproteome Reveals a Mechanism for the Regulation of Inhibitory Signals in Murine Macrophages.

BMX TEC

1.49e-05378226026062
Pubmed

Regulation of natriuretic peptides postprandially in vivo and of their receptors in adipocytes by fatty acids in vitro.

NPR1 NPR2

1.49e-05378229409758
Pubmed

A cerebellar learning model of vestibulo-ocular reflex adaptation in wild-type and mutant mice.

GABRG2 SLC12A5

1.49e-05378224849355
Pubmed

The adaptor protein Gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase.

PIK3R1 KDR

1.49e-05378216787925
Pubmed

Chromosomal distribution of three members of the human natriuretic peptide receptor/guanylyl cyclase gene family.

NPR1 NPR2

1.49e-0537821979052
Pubmed

Correlation between IDH1 gene mutation status and survival of patients treated for recurrent glioma.

KDR IDH1

1.49e-05378222199315
Pubmed

Etk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factor-induced angiogenic pathway.

BMX KDR

1.49e-05378214532277
Pubmed

PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.

PIK3R1 KDR

1.49e-05378227897192
Pubmed

Retinal degeneration protein 3 controls membrane guanylate cyclase activities in brain tissue.

NPR1 NPR2

1.49e-05378236618828
Pubmed

Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: guanylyl cyclase-linked natriuretic peptide receptors do not internalize.

NPR1 NPR2

1.49e-05378215459247
Pubmed

Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABA.

GABRG2 GABRA4

1.49e-05378217124266
Pubmed

The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.

PSMD3 CHD4 EIF3F MFF

2.03e-057178429346117
Pubmed

Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.

GABRG2 GRIA3 TTYH3

2.12e-052478322534482
Pubmed

Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.

IGF1R PIK3R1

2.97e-05478223980150
Pubmed

EZH2-, CHD4-, and IDH-linked epigenetic perturbation and its association with survival in glioma patients.

CHD4 IDH1

2.97e-05478229272522
Pubmed

Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein.

IGF1R PIK3R1

2.97e-0547827642582
Pubmed

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.

KDR IL18R1

2.97e-05478226638073
Pubmed

TGF-beta 1 modulates EGF-stimulated phosphatidylinositol 3-kinase activity in human airway smooth muscle cells.

TGFBR1 PIK3R1

2.97e-0547829435577
Pubmed

Acute stretch promotes endothelial cell proliferation in wounded healing mouse skin.

IGF1R KDR

2.97e-05478218330587
Pubmed

Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling.

IGF1R PIK3R1

2.97e-0547829852124
Pubmed

A familial mutation renders atrial natriuretic Peptide resistant to proteolytic degradation.

NPR1 NPR2

2.97e-05478219458086
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GABRG2 GRIA3 TACR1 GABRA4

3.42e-058178422723691
Pubmed

The protein tyrosine kinase family of the human genome.

BMX IGF1R KDR TEC

3.76e-058378411114734
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

TGFBR1 DNAH10 ODR4 PSMD3 DNAH5 MFF

3.84e-0527778630745168
Pubmed

Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress.

ERN1 VPS45 PLD3 DNAJB14 ERLEC1

4.65e-0517478532149426
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

SNX4 WFS1 AHCTF1 UTP20 ABCD1 PLD3 DNAJC3 DNAJB14 ERLEC1 DYNC1H1

4.82e-05942781031073040
Pubmed

Novel metastasis-related gene CIM functions in the regulation of multiple cellular stress-response pathways.

ERN1 ERLEC1

4.94e-05578221118962
Pubmed

Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival.

BMX TEC

4.94e-05578218523268
Pubmed

Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.

KDR IL18R1

4.94e-05578231923399
Pubmed

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

IGF1R REEP3

4.94e-05578222354554
Pubmed

Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study.

IGF1R PIK3R1

4.94e-05578215127203
Pubmed

ENaC is regulated by natriuretic peptide receptor-dependent cGMP signaling.

NPR1 NPR2

4.94e-05578223324181
Pubmed

Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases.

BMX TEC

4.94e-05578212573241
Pubmed

The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.

BMX TEC

4.94e-05578224722985
Pubmed

The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1.

IGF1R PIK3R1

4.94e-05578233991522
Pubmed

Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor.

IGF1R PIK3R1

4.94e-0557827541045
Pubmed

Activin receptor-like kinase 1 is essential for placental vascular development in mice.

TGFBR1 KDR

4.94e-05578217530030
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

GABRG2 NPR1 NPR2 GRIA3 TFIP11 TACR1

5.98e-0530078619086053
Pubmed

IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.

ERN1 WFS1

7.40e-05678226106220
Pubmed

Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1+ epicardial cells.

NPR1 NPR2

7.40e-05678233245046
Pubmed

Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide.

NPR1 NPR2

7.40e-0567821309330
Pubmed

Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors. Hormone pharmacology and application to solid phase screening of synthetic peptide antisera.

NPR1 NPR2

7.40e-0567821660465
Pubmed

Characterization and functional expression of the natriuretic peptide system in human lens epithelial cells.

NPR1 NPR2

7.40e-05678220700369
Pubmed

Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).

NPR1 NPR2

7.40e-0567821672777
Pubmed

Embryonic expression and multifunctional actions of the natriuretic peptides and receptors in the developing nervous system.

NPR1 NPR2

7.40e-05678215196958
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

TGFBR1 NPR1 IGF1R WFS1 UTP20 PLD3 DNAJC3 DNAJB14 ERLEC1 PCYOX1 CDON

7.44e-051201781135696571
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

GABRG2 FLNC TNN EML6 GRIA3 PSMD3 KDR CHD4 DNAJC3 DNAJB14 ERLEC1 MYBPC2

8.50e-051442781235575683
Pubmed

Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex.

GABRG2 GABRA4

1.04e-0477827560270
Pubmed

AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.

ERN1 WFS1

1.04e-04778219911006
Pubmed

Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK.

PIK3R1 TEC

1.04e-0477829178903
Pubmed

Modeled changes of cerebellar activity in mutant mice are predictive of their learning impairments.

GABRG2 SLC12A5

1.04e-04778227805050
Pubmed

RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.

IGF1R PIK3R1

1.04e-04778211964397
Pubmed

Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development.

TGFBR1 KDR

1.04e-04778216344855
Pubmed

Regulation of axonal development by natriuretic peptide hormones.

NPR1 NPR2

1.04e-04778219805191
Pubmed

The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family.

IGF1R TEC

1.04e-0477822482828
Pubmed

Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.

NPR1 NPR2

1.04e-04778219326473
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

AHCTF1 EML6 CHD4 AP4M1 DNAH5 DYNC1H1

1.04e-0433278637433992
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

WFS1 PSMD3 ABCD1 PLD3 DNAJB14 ERLEC1 PCYOX1

1.32e-0449978722810586
Pubmed

Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav.

PIK3R1 CR2

1.38e-04878216289966
Pubmed

A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminence.

GABRG2 SLC12A5

1.38e-04878227540587
Pubmed

Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth.

PIK3R1 KDR

1.38e-04878226037503
Pubmed

Comparative analysis of the signaling capabilities of the insulin receptor-related receptor.

IGF1R PIK3R1

1.38e-04878215629149
Pubmed

A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.

KDR IL18R1

1.38e-04878238906145
Pubmed

The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord.

NPR1 NPR2

1.38e-04878229472841
Pubmed

The bHLH-Zip transcription factor Tfeb is essential for placental vascularization.

KDR TEC

1.38e-0487829806910
Pubmed

Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.

UTP20 DNAH5

1.38e-04878217903303
Pubmed

Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.

NPR2 IGF1R

1.38e-04878216461637
Pubmed

Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib.

FMO3 KDR

1.77e-04978220182906
Pubmed

Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha.

PIK3R1 KDR

1.77e-04978219705443
Cytoband20q11.22-q12

FAM83D DHX35

2.85e-06278220q11.22-q12
Cytoband4p12

TEC GABRA4

5.31e-04207824p12
GeneFamilyGuanylate cyclase receptors

NPR1 NPR2 GUCY2D

9.76e-077563343
GeneFamilyDyneins, axonemal

DNAH10 DNAH5

1.24e-0317562536
GeneFamilyFibronectin type III domain containing

IGF1R TNN CDON MYBPC2

1.52e-03160564555
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRG2 GABRA4

1.56e-0319562563
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

NPR2 DENND5A

2.70e-0325562504
GeneFamilySH2 domain containing

BMX PIK3R1 TEC

3.78e-03101563741
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_1000

CCNJL NPR2 ERN1 IDH1 PLD3 CDON GABRA4

2.97e-05251757gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_1000
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RNF150 TTYH3 IDH1 PLD3 SLC12A5

1.00e-051637854b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCell3'_v3-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

CCNJL PIK3R1 TEC ITGAD IL18R1

2.04e-051897856e402fb3fc31e4cb541e3cd140d7a86c1083dbf5
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-immature_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CCNJL NPR1 WFS1 TNN KDR

2.20e-051927855af3b2b38495e925497c48f605d618bbf970965d
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERN1 WFS1 DNAJC3 ERLEC1 GABRA4

2.20e-051927856417468829517a0f6e04e7e44eec1622001d4c5c
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 GRIA3 CR2 DNAH5 CDON

2.32e-05194785f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCellGoblet|World / shred by cell class for turbinate

FAM83D DHX35 ABCD1 REEP3 ERLEC1

2.32e-0519478503b62e7cff5e7a6e7bd7d9dda273c74bf9c1f42e
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|367C / Donor, Lineage, Cell class and subclass (all cells)

RNF150 TTYH3 IDH1 PLD3 SLC12A5

2.32e-05194785e3688f4252aae5f849f025d7f453ff4c0c14590b
ToppCell(3)_MNP-(3)_Macrophage_MARCOneg|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

RNF150 TTYH3 IDH1 PLD3 SLC12A5

2.37e-05195785e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCellB_cells-Plasmablasts|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ERN1 WFS1 PLD3 DNAJC3 ERLEC1

2.55e-05198785c6cab47885be74a64351f843a741dea6d911bde4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 EML6 GRIA3 SLC12A5 GABRA4

2.55e-051987856d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 EML6 GRIA3 SLC12A5 GABRA4

2.55e-051987854ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP45 ERN1 PIK3R1 KDR IL18R1

2.61e-05199785cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CCNJL GUCY1B2 DNAH10 DNAH5

1.26e-04146784a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

GRIA3 ITGAD IL18R1 MFF

1.33e-04148784d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NPR2 SSH1 DNAH10 IL18R1

1.40e-04150784ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NWD1 DNAH10 EML6 DNAH5

1.55e-041547849ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NWD1 DNAH10 EML6 DNAH5

1.55e-0415478458072ce422d09f2de602580325eaac6c4ec6c136
ToppCellCOVID-19_Severe-NK_CD56bright|World / disease group, cell group and cell class

NWD1 AP4M1 IL18R1 TEC

1.67e-041577849dcbabb377da7e93ec9f9abf09576a92877a7e02
ToppCellPBMC-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

IGF1R DNAH10 GUCY2D ANO5

1.79e-041607844dac64e58d9366c399f3d830848ccb720d400be7
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF150 EML6 PLD3 ITGAD

1.79e-041607840544bc465af208da448858d6e174ff56f2e08a46
ToppCellFetal_29-31_weeks-Immune-mast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAM83D ITGAD IL18R1 TEC

1.92e-0416378403b2ec226adffba3ce893f3d12e549c841e662fd
ToppCellnormal-na-Lymphocytic_NK-NK_bright-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PIK3R1 PKD1L1 TEC IL18R1

1.97e-04164784b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNJL DNAH10 EML6 DNAH5

2.01e-041657841703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM83D CR2 TOP3A MYBPC2

2.06e-041667846a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM83D CR2 TOP3A MYBPC2

2.06e-041667848d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH10 TNN TACR1 DNAH5

2.16e-04168784fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH10 TNN TACR1 DNAH5

2.16e-041687847edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

RNF150 FLNC IDH1 TEC

2.26e-041707844232fe937909f93d3736988c707b8f95ce993398
ToppCellCOVID-19_Moderate-NK_CD56bright|World / disease group, cell group and cell class

CCNJL FMO3 IL18R1 TEC

2.26e-04170784caa6a534c1e9639caced9a51680f5c905f061bcc
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FSIP2 FLNC WFS1 SLCO1B3

2.36e-041727840be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R TACR1 IL18R1 TEC

2.41e-041737843612772632ddf11eb48579cae9a8ccab6b3f1f52
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

MINDY3 USP45 GRIA3 UTP20

2.41e-041737844f2843371d18af766c1892529ce286f56c956fde
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R TACR1 IL18R1 TEC

2.41e-041737844dc261ebcdb9bdcfca1451da1bd254f0dc5de203
ToppCellIPF-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

CCNJL PIK3R1 IL18R1 TEC

2.52e-04175784b6d1e40d9339426d778481fd67ab7cbc0f6cb5b2
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

WFS1 TNN EML6 ERLEC1

2.52e-041757843b5346fba617292de71963b6175e85a4f182fe30
ToppCellILEUM-non-inflamed-(5)_Plasma-(5)_IgM_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RNF150 CHD4 EIF3F

2.52e-0470783aa63c1b77a9fb15e75835cb3781f2d890f3fe328
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

WFS1 TNN EML6 ERLEC1

2.58e-04176784dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR1 FMO3 KDR DNAH5

2.58e-041767840b3491451be02c18a16cdb875645be47eb867a7f
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NPR1 LOXHD1 SLCO1B3 KDR

2.63e-04177784b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMX ABCA3 KDR CR2

2.63e-04177784d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1B2 DNAJC3 ERLEC1 GABRA4

2.63e-04177784f0487e3b439f7803e465cad44916e2e271f33d6d
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC IGF1R IL18R1 TEC

2.69e-04178784cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC PLD3 IL18R1 TEC

2.69e-0417878441745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TTYH3 PLD3 ITGAD SLC12A5

2.69e-04178784e44b0aa82890ae84fc4d1343f1c65ae2fda69a11
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC PLD3 IL18R1 TEC

2.69e-04178784eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCellEndothelial|World / shred by cell class for turbinate

NPR1 BMX KDR TACR1

2.75e-04179784052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 WFS1 GRIA3 ITGAD

2.81e-04180784bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 WFS1 GRIA3 ITGAD

2.81e-04180784839defb40f7cfb2711e9025194de636533f51bcd
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 WFS1 GRIA3 ITGAD

2.81e-0418078482965ed1b72a1873c24dd4553d39681596057316
ToppCellAT1_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

LOXHD1 WFS1 ABCD1 PCYOX1

2.81e-04180784ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FLNC BMX WFS1 KDR

2.87e-04181784b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCellfacs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 WFS1 GRIA3 ITGAD

2.87e-04181784782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|367C / Donor, Lineage, Cell class and subclass (all cells)

FLNC BMX WFS1 KDR

2.87e-04181784dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCellfacs-Marrow-B-cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 WFS1 GRIA3 ITGAD

2.87e-04181784e2481291c236105774c53883e6f20da11941df9b
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLD3 DNAJC3 ERLEC1 GABRA4

2.87e-0418178497022416d0f5a5ba9c9bd5e70ce95cf4cb19af89
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 SSH1 KDR CR2

2.93e-04182784f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC BMX WFS1 KDR

2.99e-04183784764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC BMX WFS1 KDR

2.99e-0418378438a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCellfacs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP45 WFS1 EML6 GABRA4

2.99e-04183784b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERN1 DNAJC3 ERLEC1 GABRA4

2.99e-04183784edb0069c66b1465dcc0bb5881417c6b17184fd74
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 KDR SLC12A5 GABRA4

2.99e-04183784f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LOXHD1 DNAH10 ANO5 DNAH5

3.05e-041847842cbed6462fea2622871bb7e49b0df3d984239281
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FLNC BMX WFS1 KDR

3.05e-0418478403ea613e00b45c81b752c14505a0538d698f551e
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC BMX WFS1 KDR

3.05e-0418478415cbddea9efb2346a2028d77edfe9ba32923568f
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC BMX WFS1 KDR

3.05e-041847840087c605c161fd8a39aa394f51994a04e8353bf1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LOXHD1 DNAH10 ANO5 DNAH5

3.05e-04184784ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LOXHD1 DNAH10 ANO5 DNAH5

3.05e-041847842b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC BMX WFS1 KDR

3.05e-04184784968afa6b5ba84169377a24c150bb68749fa674d9
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC BMX WFS1 KDR

3.05e-04184784920f95625978132c2b6c76654ef6298244103e2d
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

RNF150 FLNC ANO5 GABRA4

3.05e-04184784e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellControl-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

CCNJL IGF1R PIK3R1 TEC

3.11e-04185784520795866d44def5be3910ce8e728045c716a24d
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|343B / Donor, Lineage, Cell class and subclass (all cells)

RNF150 TTYH3 PLD3 SLC12A5

3.11e-04185784d4ba36bdb8b7e3a62e827269484f89f790eaa5ef
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC NPR1 LOXHD1 WFS1

3.11e-041857849de1db2ce9e44956b1214daf6e1e161334679c88
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC NPR1 LOXHD1 WFS1

3.11e-0418578418f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

FLNC BMX WFS1 KDR

3.11e-0418578497a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RNF150 TTYH3 PLD3 SLC12A5

3.18e-041867849673367cb53bafb873a01ef6bda11d9f392ce648
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR1 BMX SSH1 KDR

3.18e-04186784055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

FLNC BMX WFS1 KDR

3.18e-041867846b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC BMX WFS1 KDR

3.24e-0418778465d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC BMX WFS1 KDR

3.24e-041877844c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC BMX WFS1 KDR

3.24e-041877845274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCellCOVID-NK-|COVID / Condition, Cell_class and T cell subcluster

CCNJL IGF1R IL18R1 TEC

3.31e-04188784fabdd68a9734d35e75e1f4a4bfd5c531cfc099f1
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)|390C / Donor, Lineage, Cell class and subclass (all cells)

FLNC NPR1 BMX KDR

3.31e-04188784aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)-|390C / Donor, Lineage, Cell class and subclass (all cells)

FLNC NPR1 BMX KDR

3.31e-041887841f40b959777d18ad88d239df8cca304f062ba04c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC BMX WFS1 KDR

3.31e-0418878426915db8863f4115b46a81982e187322e21600fd
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC NWD1 WFS1 KDR

3.31e-04188784524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC BMX WFS1 KDR

3.31e-041887843f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCellHealthy_donor-NK_CD56bright|World / disease group, cell group and cell class (v2)

CCNJL PIK3R1 ITGAD IL18R1

3.31e-041887848ee359199c61c3b5b498ac35148390db5cc1a836
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC BMX WFS1 KDR

3.31e-0418878461ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC NWD1 WFS1 KDR

3.31e-04188784d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellCOVID-NK|COVID / Condition, Cell_class and T cell subcluster

CCNJL IGF1R IL18R1 TEC

3.31e-041887840beaa671611110a11e46156f54f5202cc24967a4
ToppCellHealthy_donor-NK_CD56bright|Healthy_donor / disease group, cell group and cell class (v2)

CCNJL PIK3R1 IL18R1 TEC

3.38e-041897849eac380a3bb4b685effb52d816e1960972660646
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR1 BMX SLCO1B3 KDR

3.38e-04189784fccadf8efbef17b7f12291b069c71060a71b04e2
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFS1 DNAJC3 ERLEC1 GABRA4

3.44e-04190784992539c380576bf810c00a5f926cf1ee7d57dcf5
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ABCA3 EML6 ANO5 GABRA4

3.44e-04190784b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TGFBR1 TTYH3 IDH1 PLD3

3.44e-04190784d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC BMX WFS1 KDR

3.44e-04190784b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|368C / Donor, Lineage, Cell class and subclass (all cells)

TTYH3 IDH1 PLD3 SLC12A5

3.44e-04190784cbba3d94a4c3e0b0d14f3b7c60dba5d6e097c5e3
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

WFS1 PLD3 DNAJC3 ERLEC1

3.44e-04190784ce70336679a2b713836e7497e6dc48aac612b018
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC BMX WFS1 KDR

3.51e-04191784361b123c8289015206d5e706ab2c615d9a724179
ComputationalGenes in the cancer module 65.

NPR1 NPR2 GUCY2D

9.20e-0610473MODULE_65
ComputationalGenes in the cancer module 445.

NPR1 NPR2 GUCY2D

3.44e-0515473MODULE_445
DrugPentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A

CCNJL GABRG2 FLNC NPR1 ERN1 TNN TOP3A OR1D2

3.72e-071997785264_UP
DrugSperact

NPR1 NPR2 GUCY1B2 GUCY2D

1.22e-0624774CID000123688
DrugTestosterone Propionate

TGFBR1 GABRG2 IGF1R MRPL54 GABRA4

3.42e-0668775ctd:D043343
DrugUroguanylin

NPR1 NPR2 GUCY1B2 GUCY2D

6.56e-0636774CID005488765
DrugErythrityl Tetranitrate

NPR1 NPR2

1.13e-052772DB01613
Drugguanylin

NPR1 NPR2 GUCY1B2 GUCY2D

1.48e-0544774CID005489468
DrugApstatin

ERCC8 IGF1R TACR1 TEC

2.28e-0549774CID000447280
Drugmu 0

AP4M1 TEC

3.38e-053772CID016006040
DrugNesiritide

NPR1 NPR2

3.38e-053772DB04899
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

3.92e-054762EFO_0020830
DiseaseColorectal Carcinoma

TGFBR1 FLNC ABCA3 SLCO1B3 KDR IDH1 MFF CCDC93 SLC12A5

7.98e-05702769C0009402
Diseasecystitis (implicated_via_orthology)

KDR TACR1

1.81e-048762DOID:1679 (implicated_via_orthology)
DiseaseFebrile Convulsions

GABRG2 SLC12A5

2.33e-049762C0009952
DiseaseSitus ambiguus

PKD1L1 DNAH5

6.73e-0415762C0266642
DiseaseColorectal Neoplasms

TGFBR1 FLNC ABCA3 SLCO1B3 KDR

7.54e-04277765C0009404
Diseasethyroid volume

IGF1R DNAH5

7.67e-0416762EFO_0004865
Diseaseimmature granulocyte count

PSMD3 REEP3

8.68e-0417762EFO_0803542
DiseaseUremia

TGFBR1 KDR

8.68e-0417762C0041948
DiseaseDyschondroplasias

KDR IDH1

1.09e-0319762C0013366
Diseasecystathionine measurement

TEC TEC

1.09e-0319762EFO_0010474
DiseaseLeber Congenital Amaurosis

USP45 GUCY2D

1.46e-0322762C0339527
DiseaseBronchiectasis

PIK3R1 DNAH5

1.46e-0322762C0006267
DiseaseEpilepsy, Benign Psychomotor, Childhood

KDR SLC12A5

1.60e-0323762C0393672
DiseaseEpilepsy, Lateral Temporal

KDR SLC12A5

1.60e-0323762C0393682
DiseaseUncinate Epilepsy

KDR SLC12A5

1.60e-0323762C0014558
DiseaseEpilepsy, Temporal Lobe

KDR SLC12A5

1.60e-0323762C0014556
Diseaseabdominal fat cell number

RNF150 FLNC TEC TEC

1.73e-03198764EFO_0021534
Diseaseglioblastoma (is_implicated_in)

KDR IDH1

1.74e-0324762DOID:3068 (is_implicated_in)
Diseasebody fat percentage, high density lipoprotein cholesterol measurement

DNAH10 PIK3R1

1.89e-0325762EFO_0004612, EFO_0007800
DiseaseSchizophrenia

GABRG2 GRIA3 KDR CHD4 MAGEC1 IL18R1 SLC12A5 GABRA4

1.95e-03883768C0036341
Diseasediabetes mellitus (implicated_via_orthology)

IGF1R WFS1

2.04e-0326762DOID:9351 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
TTGVLYKEDNYVIMT

ERLEC1

56

Q96DZ1
TKMEIPRTYQEYESS

ANO5

541

Q75V66
GMTRYVLDDQYVSSV

BMX

556

P51813
MDRYNVTTSKQLYTV

CCNJL

71

Q8IV13
YISGYEISQDMVQIR

ABCA3

591

Q99758
DVYKVETIGDAYMVV

NPR2

901

P20594
DVYKVETIGDAYMVV

NPR1

916

P16066
LMTQEEVSEIKSSYY

DHTKD1

471

Q96HY7
YESVMKTEPSIAEYT

DNAJC3

291

Q13217
VLDYGYVQTTSTEML

AP4M1

116

O00189
ILTDYRVVYSMTNGD

NWD1

1356

Q149M9
RIMSSYKEVTELAGY

ABCD1

401

P33897
HNKYMVTERATYIGT

PLD3

416

Q8IV08
SNYNEKVMYVEGTAV

MINDY3

391

Q9H8M7
IVLSKSYMSNEVRYE

IL18R1

441

Q13478
GKSETIQTDYIVYMD

FMO3

421

P31513
KAEMLTNVISRYTGY

MAGEC1

931

O60732
SRIQYEMEYTEGISQ

MFF

31

Q9GZY8
VYKVETIGDAYMVAS

GUCY2D

921

Q02846
RMKEIQKSIYYITGE

HSP90AB2P

251

Q58FF8
KTITITEMEYGNVYF

LOXHD1

1896

Q8IVV2
TIVDMVYSKVLQEYE

FSIP2

4696

Q5CZC0
ATEISQDKYMTIQYV

FSIP2

6056

Q5CZC0
QYAVYVKAVTLTMVE

IGF1R

576

P08069
EYIEYLSRKVSTEMG

FAM199X

191

Q6PEV8
GRRTNYTIDVYEMKV

GRIA3

376

P42263
KMYEVVYQIGTETRS

PCYOX1

291

Q9UHG3
MGRTYIVEETVGQYL

ODR4

1

Q5SWX8
EKLMTVRTITGNIYY

FAM83D

216

Q9H4H8
HMGNRVYNVTYTVKE

FLNC

2686

Q14315
IKSITGEYIVMTVYF

GABRA4

236

P48169
LYEEYTRTSQEIQMK

PIK3R1

466

P27986
IAVYTVYSGEQITML

ERCC8

316

Q13216
VYTMISRQEESTKYF

ITGAD

921

Q13349
KEEMGDYIRSYSVSQ

CCDC93

131

Q567U6
TVTRHYRMYQKGQET

IDH1

311

O75874
MVSGQKDRYTYNDTV

CR2

361

P20023
YYDTERIGVDLIMKT

EIF3F

241

O00303
LGRTEYTITMYDTKT

ERN1

156

O75460
TIKMQTENLGVVYYV

DNAJB14

286

Q8TBM8
NEVIQTSKYYMRDVT

DHX35

656

Q9H5Z1
SGDVKYVTYMVNVLE

CDON

296

Q4KMG0
VVKTTSGDYVVMSVY

GABRG2

251

P18507
VEYVMVRNEITGHTY

DENND5A

1026

Q6IQ26
SYSAVMGIVSEVEQY

DYNC1H1

1036

Q14204
SMKREYYIQLESGQV

AHCTF1

251

Q8WYP5
YTTKIYAVSIREMEG

EML6

1306

Q6ZMW3
MYVVTYVGDKDSRAI

CHD4

801

Q14839
VYRAVTDYVTVTMGE

DNAH10

3841

Q8IVF4
KQTVMTVVYGVTRYG

POLRMT

991

O00411
QLMGSYTEIRNYITV

PKD1L1

1311

Q8TDX9
TIESYVDKRMGTTYG

DNAH5

2631

Q8TE73
ISAYTYEKTLVMEQR

SLC12A5

921

Q9H2X9
YSVKDSVATVMYAVV

OR1D2

266

P34982
MYITIGTRNLQKYVS

RNF150

191

Q9ULK6
ITSYIKEMQIVDVNY

UTP20

1456

O75691
MQETYTAYLIETRSV

SNX4

76

O95219
AQAVIYEVATVTYMI

SLC47A2

326

Q86VL8
FEKYTNYEVVTMVTR

TEC

566

P42680
YEGLEMKSTRYLQTQ

TACR1

331

P25103
AVYKVETIGDAYMVV

GUCY1B2

431

O75343
YIVQAKERGYETMVN

REEP3

106

Q6NUK4
YLNRYTVTVEGMIKL

TGFBR1

291

P36897
RYMVVVYSSGRQDTE

SSH1

106

Q8WYL5
SMREGHYTAYVKVRT

USP45

741

Q70EL2
GYVQSKEMIDIYSTR

PSMD3

456

O43242
TIDKYMVRYTSADGE

TNN

911

Q9UQP3
VQLTTYAMGVNIYKE

MRPL54

66

Q6P161
AKMYVDIGYVDLSTI

SLCO1B3

231

Q9NPD5
SMVYTQSEILQKEVY

VPS45

36

Q9NRW7
GLRQIYYSMNVEVTD

TRBV27

61

A0A0K0K1C4
ETMRIAEKLYTQGYI

TOP3A

346

Q13472
DESYQSIMYIVVVVG

KDR

206

P35968
AYVTKMVEEYSVLSG

TTYH3

276

Q9C0H2
SYVVYENMKQTLGVT

SLC25A24

461

Q6NUK1
VKVIDMTGREQKVYY

TFIP11

266

Q9UBB9
VYRSEGMKVYNSTLT

WFS1

651

O76024
TTYESTKMIEGILYE

MYBPC2

696

Q14324