Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	recombination hotspot binding	PRDM9 PRDM7	2.33e-06	2	31	2	GO:0010844
GeneOntologyMolecularFunction	histone H3K36 methyltransferase activity	PRDM9 PRDM7	1.80e-04	13	31	2	GO:0046975
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	PRDM9 PRDM7	4.36e-04	20	31	2	GO:0042800
GeneOntologyBiologicalProcess	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	8.84e-06	85	32	4	GO:0032436
GeneOntologyBiologicalProcess	positive regulation of reciprocal meiotic recombination	PRDM9 PRDM7	1.40e-05	4	32	2	GO:0010845
GeneOntologyBiologicalProcess	regulation of reciprocal meiotic recombination	PRDM9 PRDM7	1.40e-05	4	32	2	GO:0010520
GeneOntologyBiologicalProcess	positive regulation of ubiquitin-dependent protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.82e-05	114	32	4	GO:2000060
GeneOntologyBiologicalProcess	positive regulation of proteasomal protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.81e-05	123	32	4	GO:1901800
GeneOntologyBiologicalProcess	regulation of proteasomal ubiquitin-dependent protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.13e-05	139	32	4	GO:0032434
GeneOntologyBiologicalProcess	positive regulation of proteolysis involved in protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	7.83e-05	148	32	4	GO:1903052
GeneOntologyBiologicalProcess	regulation of ubiquitin-dependent protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.85e-04	185	32	4	GO:2000058
GeneOntologyBiologicalProcess	circadian regulation of gene expression	NCOR1 CSNK1D CSNK1E	2.12e-04	75	32	3	GO:0032922
GeneOntologyBiologicalProcess	positive regulation of nuclear division	PRDM9 PRDM7 SH2B1	2.12e-04	75	32	3	GO:0051785
GeneOntologyBiologicalProcess	non-canonical Wnt signaling pathway	DAAM1 CSNK1D CSNK1E	2.30e-04	77	32	3	GO:0035567
GeneOntologyBiologicalProcess	regulation of proteasomal protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.17e-04	213	32	4	GO:0061136
GeneOntologyBiologicalProcess	positive regulation of non-canonical Wnt signaling pathway	CSNK1D CSNK1E	3.51e-04	18	32	2	GO:2000052
GeneOntologyBiologicalProcess	negative regulation of NLRP3 inflammasome complex assembly	CSNK1A1L CSNK1A1	3.92e-04	19	32	2	GO:1900226
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	4.10e-04	228	32	4	GO:0045732
GeneOntologyBiologicalProcess	proteasome-mediated ubiquitin-dependent protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E MAEA	4.57e-04	424	32	5	GO:0043161
GeneOntologyBiologicalProcess	negative regulation of inflammasome-mediated signaling pathway	CSNK1A1L CSNK1A1	4.81e-04	21	32	2	GO:0141086
GeneOntologyBiologicalProcess	regulation of proteolysis involved in protein catabolic process	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.25e-04	255	32	4	GO:1903050
GeneOntologyBiologicalProcess	positive regulation of meiotic nuclear division	PRDM9 PRDM7	7.40e-04	26	32	2	GO:0045836
GeneOntologyBiologicalProcess	regulation of canonical Wnt signaling pathway	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	9.46e-04	285	32	4	GO:0060828
GeneOntologyBiologicalProcess	Wnt signaling pathway	DAAM1 CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.11e-03	516	32	5	GO:0016055
GeneOntologyBiologicalProcess	regulation of non-canonical Wnt signaling pathway	CSNK1D CSNK1E	1.12e-03	32	32	2	GO:2000050
GeneOntologyCellularComponent	beta-catenin destruction complex	CSNK1A1L CSNK1A1	1.75e-04	13	32	2	GO:0030877
GeneOntologyCellularComponent	ciliary basal body	DAAM1 CSNK1A1L CSNK1A1 CSNK1D	2.15e-04	195	32	4	GO:0036064
GeneOntologyCellularComponent	spindle	NCOR1 CSNK1A1L CSNK1A1 CSNK1D MAEA	6.93e-04	471	32	5	GO:0005819
GeneOntologyCellularComponent	mRNA cleavage and polyadenylation specificity factor complex	CSNK1A1L CSNK1A1	7.21e-04	26	32	2	GO:0005847
GeneOntologyCellularComponent	mRNA cleavage factor complex	CSNK1A1L CSNK1A1	1.03e-03	31	32	2	GO:0005849
GeneOntologyCellularComponent	supramolecular fiber	ARHGAP4 CSNK1A1L CSNK1A1 CSNK1D RYR3 SMTNL2 WDR47	1.73e-03	1179	32	7	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	ARHGAP4 CSNK1A1L CSNK1A1 CSNK1D RYR3 SMTNL2 WDR47	1.80e-03	1187	32	7	GO:0099081
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	ARHGAP4 CSNK1A1L CSNK1A1 CSNK1D SMTNL2 WDR47	2.16e-03	899	32	6	GO:0099513
MousePheno	abnormal circadian behavior period	NCOR1 CSNK1D CSNK1E	3.06e-05	36	24	3	MP:0020468
Domain	SSXRD	PRDM9 PRDM7	7.91e-05	8	32	2	PF09514
Domain	SSXRD_motif	PRDM9 PRDM7	7.91e-05	8	32	2	IPR019041
Domain	CTLH	MAEA WDR47	1.02e-04	9	32	2	SM00668
Domain	CTLH_C	MAEA WDR47	1.27e-04	10	32	2	IPR006595
Domain	CTLH	MAEA WDR47	1.27e-04	10	32	2	PS50897
Domain	KRAB_RELATED	PRDM9 PRDM7	1.55e-04	11	32	2	PS50806
Domain	Krueppel-associated_box-rel	PRDM9 PRDM7	2.19e-04	13	32	2	IPR003655
Domain	LisH	MAEA WDR47	1.05e-03	28	32	2	IPR006594
Domain	LisH	MAEA WDR47	1.05e-03	28	32	2	SM00667
Domain	LISH	MAEA WDR47	1.05e-03	28	32	2	PS50896
Domain	SET	PRDM9 PRDM7	2.81e-03	46	32	2	SM00317
Domain	Ser/Thr_kinase_AS	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.09e-03	357	32	4	IPR008271
Domain	KRAB	ZNF470 PRDM9 PRDM7 ZNF785	3.12e-03	358	32	4	PF01352
Domain	PROTEIN_KINASE_ST	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.25e-03	362	32	4	PS00108
Domain	SET_dom	PRDM9 PRDM7	3.31e-03	50	32	2	IPR001214
Domain	SET	PRDM9 PRDM7	3.31e-03	50	32	2	PS50280
Domain	KRAB	ZNF470 PRDM9 PRDM7 ZNF785	3.48e-03	369	32	4	SM00349
Domain	KRAB	ZNF470 PRDM9 PRDM7 ZNF785	3.52e-03	370	32	4	IPR001909
Domain	Protein_kinase_ATP_BS	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.83e-03	379	32	4	IPR017441
Domain	Pkinase	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.90e-03	381	32	4	PF00069
Domain	CH	IQGAP3 SMTNL2	5.53e-03	65	32	2	SM00033
Domain	zf-C2H2	ZNF470 PRDM9 PRDM7 ZNF785 ZSCAN4	6.08e-03	693	32	5	PF00096
Domain	CH	IQGAP3 SMTNL2	6.39e-03	70	32	2	PF00307
Domain	-	IQGAP3 SMTNL2	6.57e-03	71	32	2	1.10.418.10
Domain	CH	IQGAP3 SMTNL2	6.93e-03	73	32	2	PS50021
Domain	CH-domain	IQGAP3 SMTNL2	7.30e-03	75	32	2	IPR001715
Domain	PROTEIN_KINASE_ATP	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	7.51e-03	459	32	4	PS00107
Domain	Prot_kinase_dom	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	9.34e-03	489	32	4	IPR000719
Domain	PROTEIN_KINASE_DOM	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	9.60e-03	493	32	4	PS50011
Domain	ZINC_FINGER_C2H2_2	ZNF470 PRDM9 PRDM7 ZNF785 ZSCAN4	9.64e-03	775	32	5	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF470 PRDM9 PRDM7 ZNF785 ZSCAN4	9.74e-03	777	32	5	PS00028
Domain	Rho_GTPase_activation_prot	ARHGAP4 IQGAP3	9.93e-03	88	32	2	IPR008936
Domain	Znf_C2H2	ZNF470 PRDM9 PRDM7 ZNF785 ZSCAN4	1.12e-02	805	32	5	IPR007087
Domain	ZnF_C2H2	ZNF470 PRDM9 PRDM7 ZNF785 ZSCAN4	1.14e-02	808	32	5	SM00355
Domain	Kinase-like_dom	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.32e-02	542	32	4	IPR011009
Pathway	WP_HEDGEHOG_SIGNALING_WP4249	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.07e-06	43	26	4	M39706
Pathway	WP_WNT_SIGNALING_PATHWAY	DAAM1 CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.52e-06	110	26	5	MM15977
Pathway	PID_HEDGEHOG_GLI_PATHWAY	CSNK1A1 CSNK1D CSNK1E SAP30	1.67e-06	48	26	4	M219
Pathway	KEGG_HEDGEHOG_SIGNALING_PATHWAY	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.13e-06	56	26	4	M1053
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	CSNK1A1 CSNK1D CSNK1E	4.46e-06	18	26	3	M31
Pathway	PID_FOXO_PATHWAY	CSNK1A1 CSNK1D CSNK1E	9.70e-05	49	26	3	M136
Pathway	WP_WNT_SIGNALING_WP363	CSNK1A1 CSNK1D CSNK1E	1.09e-04	51	26	3	M39721
Pathway	KEGG_WNT_SIGNALING_PATHWAY	DAAM1 CSNK1A1L CSNK1A1 CSNK1E	1.57e-04	151	26	4	M19428
Pathway	PID_P53_REGULATION_PATHWAY	CSNK1A1 CSNK1D CSNK1E	1.69e-04	59	26	3	M261
Pathway	KEGG_CIRCADIAN_RHYTHM_MAMMAL	CSNK1D CSNK1E	2.52e-04	13	26	2	M18009
Pathway	REACTOME_CIRCADIAN_CLOCK	NCOR1 CSNK1D CSNK1E	2.81e-04	70	26	3	M938
Pathway	REACTOME_ACTIVATION_OF_SMO	CSNK1A1L CSNK1A1	2.94e-04	14	26	2	MM15228
Pathway	WP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS	MBOAT1 CSNK1A1	4.37e-04	17	26	2	M39525
Pathway	REACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE	CSNK1A1L CSNK1A1	4.91e-04	18	26	2	MM14759
Pathway	WP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA	CSNK1A1L CSNK1A1 CSNK1E	5.69e-04	89	26	3	M39563
Pathway	WNT_SIGNALING	DAAM1 CSNK1A1 CSNK1D	5.69e-04	89	26	3	M5493
Pathway	WP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER	CSNK1A1L CSNK1A1 CSNK1E	7.54e-04	98	26	3	M39731
Pathway	REACTOME_SIGNALING_BY_WNT	DAAM1 CSNK1A1L CSNK1A1 CSNK1E	8.98e-04	239	26	4	MM14756
Pathway	REACTOME_HEDGEHOG_OFF_STATE	CSNK1A1L CSNK1A1 ADCY5	9.22e-04	105	26	3	MM15206
Pathway	WP_WNT_SIGNALING_WP428	DAAM1 CSNK1A1 CSNK1E	1.14e-03	113	26	3	M39669
Pathway	WP_ALZHEIMERS_DISEASE	CSNK1A1L CSNK1A1 CSNK1E RYR3	1.25e-03	261	26	4	M42565
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	CSNK1A1L CSNK1A1	1.47e-03	31	26	2	MM15154
Pathway	PID_WNT_NONCANONICAL_PATHWAY	DAAM1 CSNK1A1	1.57e-03	32	26	2	M23
Pathway	REACTOME_SIGNALING_BY_HEDGEHOG	CSNK1A1L CSNK1A1 ADCY5	1.98e-03	137	26	3	MM15182
Pathway	WP_MELATONIN_METABOLISM_AND_EFFECTS	CSNK1D CSNK1E	2.09e-03	37	26	2	M39418
Pathway	WP_INFLUENCE_OF_LAMINOPATHIES_ON_WNT_SIGNALING	CSNK1A1L CSNK1A1	2.09e-03	37	26	2	M39817
Pathway	REACTOME_RHOA_GTPASE_CYCLE	ARHGAP4 DAAM1 IQGAP3	2.20e-03	142	26	3	MM15576
Pathway	REACTOME_RHOA_GTPASE_CYCLE	ARHGAP4 DAAM1 IQGAP3	2.52e-03	149	26	3	M41805
Pathway	WP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS	CSNK1A1L CSNK1A1 CSNK1E RYR3	2.81e-03	326	26	4	M39379
Pathway	REACTOME_CDC42_GTPASE_CYCLE	ARHGAP4 DAAM1 IQGAP3	2.82e-03	155	26	3	M41808
Pathway	WP_WNT_SIGNALING_IN_KIDNEY_DISEASE	CSNK1A1L CSNK1A1	2.95e-03	44	26	2	MM15878
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	CSNK1A1L CSNK1A1 CSNK1E	2.97e-03	158	26	3	MM14791
Pathway	BIOCARTA_NFAT_PATHWAY	CSNK1A1L CSNK1A1	3.65e-03	49	26	2	MM1442
Pubmed	Physiological role for casein kinase 1 in glutamatergic synaptic transmission.	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	8.84e-12	6	32	4	16014721
Pubmed	Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism.	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	4.12e-11	8	32	4	17244647
Pubmed	The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	4.12e-11	8	32	4	21930935
Pubmed	Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin.	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	4.12e-11	8	32	4	17101137
Pubmed	Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7.	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.23e-10	10	32	4	25500533
Pubmed	A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.	CSNK1A1 CSNK1D CSNK1E	7.07e-10	3	32	3	25665722
Pubmed	Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.	CSNK1A1 CSNK1D CSNK1E	2.83e-09	4	32	3	7797465
Pubmed	Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.	CSNK1A1L CSNK1A1 CSNK1D CSNK1E IQGAP3 MAEA	7.35e-09	161	32	6	36398662
Pubmed	Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways.	CSNK1A1L CSNK1A1 CSNK1E	1.41e-08	6	32	3	11884395
Pubmed	High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.	CSNK1A1 CSNK1D CSNK1E	1.41e-08	6	32	3	21179498
Pubmed	Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.	CSNK1A1 CSNK1D CSNK1E	2.47e-08	7	32	3	12000790
Pubmed	SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis.	CSNK1A1 CSNK1D CSNK1E	2.47e-08	7	32	3	30177679
Pubmed	Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.	CSNK1A1 CSNK1D CSNK1E	5.92e-08	9	32	3	20708156
Pubmed	Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex.	CSNK1A1L CSNK1A1 CSNK1E	1.16e-07	11	32	3	21709260
Pubmed	Association of CPI-17 with protein kinase C and casein kinase I.	CSNK1A1 CSNK1D CSNK1E	3.19e-07	15	32	3	15003508
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	CSNK1A1 CSNK1D CSNK1E DMXL1	7.23e-07	76	32	4	27542412
Pubmed	Tissue-specific distribution of mouse casein kinase I alpha mRNA.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	9522121
Pubmed	Casein kinase 1 alpha regulates chromosome congression and separation during mouse oocyte meiotic maturation and early embryo development.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	23690993
Pubmed	Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	25994086
Pubmed	Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.	CSNK1D CSNK1E	8.20e-07	2	32	2	25404202
Pubmed	CSNK1A1/CK1α suppresses autoimmunity by restraining the CGAS-STING1 signaling.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	37723657
Pubmed	Casein Kinase 1α Regulates Testosterone Synthesis and Testis Development in Adult Mice.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	36929849
Pubmed	Class III β-Tubulin Expression Is of Value in Selecting nab -Paclitaxel and Gemcitabine as First-Line Therapy in Unresectable Pancreatic Cancer.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	35695793
Pubmed	Csnk1a1 inhibition modulates the inflammatory secretome and enhances response to radiotherapy in glioma.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	34216174
Pubmed	Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.	CSNK1D CSNK1E	8.20e-07	2	32	2	9632646
Pubmed	Casein Kinase 1α as a Novel Factor Affects Thyrotropin Synthesis via PKC/ERK/CREB Signaling.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	37108197
Pubmed	Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.	CSNK1D CSNK1E	8.20e-07	2	32	2	19043076
Pubmed	An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.	CSNK1D CSNK1E	8.20e-07	2	32	2	22981886
Pubmed	Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	23354688
Pubmed	CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.	CSNK1D CSNK1E	8.20e-07	2	32	2	24424021
Pubmed	Knockdown of Csnk1a1 results in preimplantation developmental arrest in mice.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	36542875
Pubmed	Exploring the role of casein kinase 1α splice variants across cancer cell lines.	CSNK1A1L CSNK1A1	8.20e-07	2	32	2	38852281
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	CSNK1D CSNK1E SMTNL2	1.08e-06	22	32	3	22305495
Pubmed	Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.	DAAM1 CSNK1A1L CSNK1A1 CSNK1D	1.43e-06	90	32	4	19515997
Pubmed	Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.	CSNK1D CSNK1E	2.46e-06	3	32	2	28963394
Pubmed	Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesity.	CSNK1D CSNK1E	2.46e-06	3	32	2	27439882
Pubmed	Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.	CSNK1D CSNK1E	2.46e-06	3	32	2	31353086
Pubmed	Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling.	CSNK1A1L CSNK1A1	2.46e-06	3	32	2	19805514
Pubmed	Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.	CSNK1D CSNK1E	2.46e-06	3	32	2	8786104
Pubmed	Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.	CSNK1D CSNK1E	2.46e-06	3	32	2	22384121
Pubmed	Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.	CSNK1D CSNK1E	2.46e-06	3	32	2	25724478
Pubmed	Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.	CSNK1A1L CSNK1A1	2.46e-06	3	32	2	24616378
Pubmed	Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.	CSNK1A1L CSNK1A1	2.46e-06	3	32	2	25242043
Pubmed	CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.	CSNK1A1L CSNK1A1	2.46e-06	3	32	2	28878021
Pubmed	CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.	CSNK1D CSNK1E	2.46e-06	3	32	2	19805222
Pubmed	CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.	CSNK1D CSNK1E	2.46e-06	3	32	2	32321936
Pubmed	Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.	CSNK1D CSNK1E	2.46e-06	3	32	2	12270714
Pubmed	Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.	CSNK1A1L CSNK1A1	2.46e-06	3	32	2	26811327
Pubmed	Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.	CSNK1A1L CSNK1A1	2.46e-06	3	32	2	28655862
Pubmed	CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch.	CSNK1D CSNK1E	4.92e-06	4	32	2	29784789
Pubmed	Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation.	CSNK1A1L CSNK1A1	4.92e-06	4	32	2	38147624
Pubmed	Cx43 phosphorylation sites regulate pancreatic cancer metastasis.	CSNK1A1L CSNK1A1	4.92e-06	4	32	2	33603164
Pubmed	Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.	CSNK1D CSNK1E	4.92e-06	4	32	2	37578019
Pubmed	The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.	CSNK1A1L CSNK1A1	4.92e-06	4	32	2	32728212
Pubmed	Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin.	NCOR1 SAP30	4.92e-06	4	32	2	10441327
Pubmed	Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitro.	CSNK1D CSNK1E	4.92e-06	4	32	2	20421981
Pubmed	Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth.	CSNK1D CSNK1E	4.92e-06	4	32	2	21422228
Pubmed	Regulation of p53-MDMX interaction by casein kinase 1 alpha.	CSNK1A1L CSNK1A1	4.92e-06	4	32	2	16024788
Pubmed	Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model.	CSNK1D CSNK1E	4.92e-06	4	32	2	31334659
Pubmed	A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.	CSNK1A1L CSNK1A1	4.92e-06	4	32	2	30487124
Pubmed	p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs.	CSNK1D CSNK1E	4.92e-06	4	32	2	9349507
Pubmed	FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning.	CSNK1A1L CSNK1A1	4.92e-06	4	32	2	31338967
Pubmed	The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum.	CSNK1A1 CSNK1D	4.92e-06	4	32	2	8972483
Pubmed	Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes.	PRDM9 PRDM7	4.92e-06	4	32	2	18231586
Pubmed	Involvement of casein kinase Iepsilon in cytokine-induced granulocytic differentiation.	CSNK1D CSNK1E	4.92e-06	4	32	2	15070676
Pubmed	The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.	CSNK1D CSNK1E	4.92e-06	4	32	2	20192920
Pubmed	PML enhances the regulation of p53 by CK1 in response to DNA damage.	CSNK1A1 CSNK1D	4.92e-06	4	32	2	18246126
Pubmed	Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon.	CSNK1D CSNK1E	8.19e-06	5	32	2	10848614
Pubmed	Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome.	CSNK1A1L CSNK1A1	8.19e-06	5	32	2	30651631
Pubmed	Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells.	CSNK1D CSNK1E	8.19e-06	5	32	2	11865049
Pubmed	Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.	CSNK1D CSNK1E	8.19e-06	5	32	2	29191835
Pubmed	Crbn I391V is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice.	CSNK1A1L CSNK1A1	8.19e-06	5	32	2	30064974
Pubmed	Casein kinase 1 delta regulates the pace of the mammalian circadian clock.	CSNK1D CSNK1E	8.19e-06	5	32	2	19414593
Pubmed	Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin.	CSNK1D CSNK1E	8.19e-06	5	32	2	17027228
Pubmed	The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer.	CSNK1D CSNK1E	8.19e-06	5	32	2	33754069
Pubmed	CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway†.	CSNK1A1L CSNK1A1	8.19e-06	5	32	2	37944068
Pubmed	Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification.	CSNK1A1L CSNK1A1	8.19e-06	5	32	2	36989576
Pubmed	Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock.	CSNK1D CSNK1E	8.19e-06	5	32	2	19948962
Pubmed	Desynchrony between brain and peripheral clocks caused by CK1δ/ε disruption in GABA neurons does not lead to adverse metabolic outcomes.	CSNK1D CSNK1E	8.19e-06	5	32	2	29463694
Pubmed	Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer.	CSNK1A1L CSNK1A1	8.19e-06	5	32	2	25628462
Pubmed	A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.	CSNK1A1L CSNK1A1	8.19e-06	5	32	2	23890787
Pubmed	CKIα ablation highlights a critical role for p53 in invasiveness control.	CSNK1A1L CSNK1A1	8.19e-06	5	32	2	21331045
Pubmed	Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide.	CSNK1A1L CSNK1A1	1.23e-05	6	32	2	15687492
Pubmed	Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.	CSNK1A1 CSNK1D	1.23e-05	6	32	2	11955436
Pubmed	Casein kinase I epsilon associates with and phosphorylates the tight junction protein occludin.	CSNK1A1 CSNK1E	1.23e-05	6	32	2	16616143
Pubmed	A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).	CSNK1D CSNK1E	1.23e-05	6	32	2	20048001
Pubmed	Identification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathway.	CSNK1D CSNK1E	1.23e-05	6	32	2	22609948
Pubmed	Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.	CSNK1D CSNK1E	1.23e-05	6	32	2	18708403
Pubmed	Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2.	CSNK1D CSNK1E	1.23e-05	6	32	2	17962809
Pubmed	Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival.	CSNK1A1L CSNK1A1	1.23e-05	6	32	2	19118383
Pubmed	Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.	CSNK1D CSNK1E	1.23e-05	6	32	2	11818547
Pubmed	Degradation of Tiam1 by casein kinase 1 and the SCFβTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling.	CSNK1A1 CSNK1E	1.23e-05	6	32	2	25124033
Pubmed	Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.	CSNK1A1 CSNK1E	1.23e-05	6	32	2	11583622
Pubmed	Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex.	CSNK1A1 CSNK1E	1.23e-05	6	32	2	17318175
Pubmed	MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling.	CSNK1A1L CSNK1A1	1.23e-05	6	32	2	32511789
Pubmed	MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.	CSNK1A1L CSNK1A1	1.23e-05	6	32	2	33667384
Pubmed	The synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathway.	CSNK1A1L CSNK1A1	1.72e-05	7	32	2	17686994
Pubmed	Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.	CSNK1A1L CSNK1A1	1.72e-05	7	32	2	25644602
Pubmed	The yin-yang of PR-domain family genes in tumorigenesis.	PRDM9 PRDM7	1.72e-05	7	32	2	10668202
Pubmed	Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein.	CSNK1A1 CSNK1D	1.72e-05	7	32	2	10617630
Interaction	DBNDD1 interactions	CSNK1A1 CSNK1D CSNK1E	1.45e-08	4	32	3	int:DBNDD1
Interaction	FKBPL interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.33e-07	37	32	4	int:FKBPL
Interaction	SNX22 interactions	CSNK1A1 CSNK1D CSNK1E	1.03e-06	13	32	3	int:SNX22
Interaction	DVL2 interactions	DAAM1 CSNK1A1L CSNK1A1 CSNK1D CSNK1E IQGAP3 FREM1 MAEA	1.90e-06	557	32	8	int:DVL2
Interaction	ANKRD49 interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.40e-06	60	32	4	int:ANKRD49
Interaction	DCK interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.31e-06	65	32	4	int:DCK
Interaction	ARHGAP22 interactions	CSNK1A1 CSNK1D CSNK1E MAEA	3.97e-06	68	32	4	int:ARHGAP22
Interaction	PPP1R14A interactions	CSNK1A1 CSNK1D CSNK1E	5.49e-06	22	32	3	int:PPP1R14A
Interaction	ATOH1 interactions	CSNK1A1 CSNK1D CSNK1E DMXL1	7.61e-06	80	32	4	int:ATOH1
Interaction	FAM83D interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	8.39e-06	82	32	4	int:FAM83D
Interaction	FAM110D interactions	CSNK1A1 CSNK1D CSNK1E	9.22e-06	26	32	3	int:FAM110D
Interaction	SNX24 interactions	CSNK1A1 CSNK1D CSNK1E	2.30e-05	35	32	3	int:SNX24
Interaction	ZNF618 interactions	CSNK1A1 CSNK1D CSNK1E	2.51e-05	36	32	3	int:ZNF618
Interaction	HMMR interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.59e-05	109	32	4	int:HMMR
Interaction	FAM83A interactions	CSNK1A1L CSNK1A1 CSNK1E	3.45e-05	40	32	3	int:FAM83A
Interaction	FAM83B interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.90e-05	140	32	4	int:FAM83B
Interaction	FAM83H interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	7.09e-05	141	32	4	int:FAM83H
Interaction	DRICH1 interactions	CSNK1D CSNK1E	1.09e-04	10	32	2	int:DRICH1
Interaction	MTMR4 interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.10e-04	158	32	4	int:MTMR4
Interaction	CACNG4 interactions	CSNK1D CSNK1E IQGAP3	1.11e-04	59	32	3	int:CACNG4
Interaction	DBNDD2 interactions	CSNK1D CSNK1E	1.33e-04	11	32	2	int:DBNDD2
Interaction	GAPVD1 interactions	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.82e-04	180	32	4	int:GAPVD1
Interaction	FAM110C interactions	CSNK1D CSNK1E	1.88e-04	13	32	2	int:FAM110C
Interaction	MIER1 interactions	NCOR1 CSNK1E SAP30	2.75e-04	80	32	3	int:MIER1
Interaction	PPP4R1L interactions	NCOR1 IQGAP3 DMXL1	3.52e-04	87	32	3	int:PPP4R1L
Interaction	ZNF217 interactions	CSNK1A1 ZSCAN4 SAP30	3.89e-04	90	32	3	int:ZNF217
Interaction	BACH2 interactions	NCOR1 CSNK1E MAEA	3.89e-04	90	32	3	int:BACH2
Interaction	C6orf141 interactions	NCOR1 CSNK1A1 CSNK1D	4.15e-04	92	32	3	int:C6orf141
Interaction	STOX2 interactions	CSNK1D CSNK1E	5.03e-04	21	32	2	int:STOX2
Interaction	FAM170A interactions	CSNK1A1L CSNK1A1	5.53e-04	22	32	2	int:FAM170A
Interaction	FAM110A interactions	CSNK1D CSNK1E ZSCAN4	5.61e-04	102	32	3	int:FAM110A
Interaction	PER3 interactions	CSNK1D CSNK1E	6.60e-04	24	32	2	int:PER3
Interaction	FAM199X interactions	CSNK1D CSNK1E	7.16e-04	25	32	2	int:FAM199X
Interaction	BACH1 interactions	NCOR1 CSNK1A1L CSNK1A1	7.18e-04	111	32	3	int:BACH1
Interaction	SMARCA4 interactions	NCOR1 CSNK1A1 CSNK1D CSNK1E SAP30	7.48e-04	462	32	5	int:SMARCA4
Interaction	FAM83G interactions	CSNK1A1L CSNK1A1	7.75e-04	26	32	2	int:FAM83G
Interaction	SSMEM1 interactions	CSNK1A1 CSNK1D CSNK1E	8.16e-04	116	32	3	int:SSMEM1
Interaction	KLHL22 interactions	CSNK1A1 CSNK1D CSNK1E	1.01e-03	125	32	3	int:KLHL22
Cytoband	4p16.3	NAT8L MAEA	1.62e-03	85	32	2	4p16.3
Cytoband	19q13.43	ZNF470 ZSCAN4	1.70e-03	87	32	2	19q13.43
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM9 PRDM7	1.73e-04	17	21	2	1197
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF470 PRDM9 PRDM7 ZNF785 ZSCAN4	1.17e-03	718	21	5	28
Coexpression	GSE27786_LIN_NEG_VS_MONO_MAC_DN	NCOR1 CSNK1E SH2B1 RYR3 WDR47	4.19e-06	200	32	5	M4798
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_UP	CSNK1A1L CSNK1A1	3.02e-05	7	32	2	MM567
Drug	di-t-butylphosphite	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.71e-10	10	32	4	CID000518693
Drug	2-amino-5-(N-ethylcarboxyamido)-pentanoic acid	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.71e-10	10	32	4	CID000194789
Drug	CKI-8	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.71e-10	10	32	4	CID000486026
Drug	Asptpsa	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.71e-10	10	32	4	CID000132853
Drug	5-chloroisoquinoline	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.28e-09	13	32	4	CID000224933
Drug	AC1Q5W8U	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	4.34e-09	15	32	4	CID000006483
Drug	S-ethylcysteine	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.42e-08	28	32	4	CID000030993
Drug	NG97	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	8.58e-08	30	32	4	CID006604931
Drug	diisopropylphosphate	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	8.58e-08	30	32	4	CID000074162
Drug	cKP	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	8.58e-08	30	32	4	CID005494415
Drug	IC 261	CSNK1A1 CSNK1D CSNK1E	8.79e-08	7	32	3	ctd:C411652
Drug	AC1L1GFH	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.82e-07	43	32	4	CID000003660
Drug	6-hydroxymethyl-7,8-dihydropterin	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	4.19e-07	44	32	4	CID000000218
Drug	Pp55	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	7.07e-07	50	32	4	CID000132900
Drug	CKI-7	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	8.96e-07	53	32	4	CID000129236
Drug	anthraquinone	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.48e-06	60	32	4	CID000006780
Drug	methylglyoxal bis(guanylhydrazone	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.58e-06	61	32	4	CID000009991
Drug	mazindol	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.84e-06	76	32	4	CID000004020
Drug	CK2 inhibitor	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	6.59e-06	87	32	4	CID000001694
Drug	DAPH1	DAAM1 CSNK1D CSNK1E	7.21e-06	27	32	3	CID000133027
Drug	cnicin	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	8.23e-06	92	32	4	CID000091176
Drug	IC261	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	9.75e-06	96	32	4	CID000003674
Drug	rutin	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	1.06e-05	98	32	4	CID005280805
Drug	australifungin	CSNK1D CSNK1E	1.91e-05	5	32	2	CID005276375
Drug	Cys-cys	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.28e-05	119	32	4	CID000152238
Drug	Kemptide	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.68e-05	124	32	4	CID000100074
Drug	Attpsa	CSNK1D CSNK1E	2.86e-05	6	32	2	CID005487511
Drug	NDSB195	CSNK1D CSNK1E	2.86e-05	6	32	2	CID000448830
Drug	NSC401575	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.13e-05	129	32	4	CID000003165
Drug	2,3-DPG	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	3.96e-05	137	32	4	CID000000061
Drug	emodin	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	4.55e-05	142	32	4	CID000003220
Drug	dl-Lysine	CSNK1A1L CSNK1A1 CSNK1D CSNK1E ADCY5	4.92e-05	290	32	5	CID000000866
Drug	7,8-diOH-CPZ	CSNK1D CSNK1E	6.85e-05	9	32	2	CID000159916
Drug	DAPH2	DAAM1 CSNK1D CSNK1E	7.38e-05	58	32	3	CID006711154
Drug	CK1 inhibitor	CSNK1D CSNK1E	1.04e-04	11	32	2	CID006419753
Drug	BE-23372M	CSNK1D CSNK1E	1.04e-04	11	32	2	CID005311105
Drug	NSC406942	CSNK1A1L CSNK1A1 CSNK1D CSNK1E ADCY5 RYR3	1.19e-04	565	32	6	CID000001115
Drug	K-Cl	CSNK1A1L CSNK1A1 CSNK1D CSNK1E ADCY5 RYR3	1.21e-04	567	32	6	CID000004873
Drug	pppAp	CSNK1D CSNK1E	1.48e-04	13	32	2	CID000189064
Drug	D0303	CSNK1D CSNK1E	1.48e-04	13	32	2	CID009809426
Drug	Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; PC3; HT_HG-U133A	PRDM9 CSNK1E SH2B1 STC1	1.68e-04	199	32	4	6342_UP
Drug	matairesinol	CSNK1D CSNK1E	1.72e-04	14	32	2	CID000119205
Drug	Gvapspat amide	RYR3 MAEA	1.99e-04	15	32	2	CID000125015
Drug	sulfonamide analog 1	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.18e-04	213	32	4	CID005327336
Drug	Phosphoryl	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.26e-04	215	32	4	CID006857426
Drug	DNTB	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.30e-04	216	32	4	CID000015325
Drug	32 P	CSNK1A1L CSNK1A1 CSNK1D CSNK1E ADCY5	2.36e-04	405	32	5	CID000448772
Drug	1q66	NCOR1 SAP30	2.57e-04	17	32	2	CID006323390
Drug	1,4-bis-(phenoxyacetyl)piperazine	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.69e-04	225	32	4	CID001008511
Drug	LMWH	CSNK1A1L CSNK1A1 CSNK1D CSNK1E ADCY5 RYR3	2.83e-04	663	32	6	CID000000772
Drug	Akti-1/2	CSNK1D CSNK1E	3.22e-04	19	32	2	CID010196499
Drug	A-443654	CSNK1D CSNK1E	3.58e-04	20	32	2	CID010172943
Drug	spermidine	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	4.19e-04	253	32	4	CID000001102
Drug	NHS-LC-biotin	CSNK1D CSNK1E	4.75e-04	23	32	2	CID000083874
Drug	NSC-364372	CSNK1A1L CSNK1A1 CSNK1D CSNK1E SH2B1	5.33e-04	484	32	5	CID000435143
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1A1L CSNK1A1 CSNK1D CSNK1E	2.63e-11	7	29	4	DOID:0060807 (implicated_via_orthology)
Disease	progression free survival, ovarian serous carcinoma	ABCA13 IQGAP3	2.13e-04	22	29	2	EFO_0004920, EFO_1001516
Disease	disease progression measurement	ADCY5 RYR3	1.65e-03	61	29	2	EFO_0008336
Disease	Alzheimer's disease (is_marker_for)	CSNK1A1 CSNK1D CSNK1E	2.02e-03	257	29	3	DOID:10652 (is_marker_for)
Disease	response to angiotensin-converting enzyme inhibitor	MBOAT1 SH2B1	2.67e-03	78	29	2	EFO_0005325
Disease	urate measurement, bone density	MBOAT1 SNX19 CLVS1 FREM1	3.00e-03	619	29	4	EFO_0003923, EFO_0004531
Disease	DNA methylation	ABCA13 FREM1 SMTNL2 STC1	3.70e-03	656	29	4	GO_0006306

Protein segments in the cluster

Peptide	Gene	Start	Entry
YNLSKHYRRFFQNII	ABCA13	4721	Q86UQ4
LERLYQRYFFRLNQS	ADCY5	226	O95622
FNFYNYLRTHPLLLR	DMXL1	1811	Q9Y485
LIQQFRYDNYRLHQL	MAEA	266	Q7L5Y9
YRLFITFHLQNFRNG	LCN9	116	Q8WX39
YSYLRQLFRNLFHRQ	CSNK1D	266	P48730
FLQRDLFNGIIYYRH	FREM1	586	Q5H8C1
FRILFRTLNHQYDYT	CSNK1A1L	281	Q8N752
ARRQYLRRLHYFQKN	IQGAP3	806	Q86VI3
VAFQYHRQIFYRTCR	PRDM9	331	Q9NQV7
RINHYQQRLQSLYFK	DAAM1	766	Q9Y4D1
ARAVRNNYRHYFLSS	MBOAT1	401	Q6ZNC8
FARRFRLYLASHPQY	SH2B1	41	Q9NRF2
YQLQVNTLRRYKRHF	SAP30	151	O75446
FRILFRTLNHQYDYT	CSNK1A1	281	P48729
YFNYKRRHNLDNLLQ	NCOR1	666	O75376
VAFQYHRQIFYRTCR	PRDM7	331	Q9NQW5
VLRYLFTFLNHLAQY	ARHGAP4	631	P98171
LPNHFSNRYYNRLVR	STC1	151	P52823
FRLLAQYFQYRQLNL	CLVS1	91	Q8IUQ0
FQEYYRQRLRYQQHL	WDR47	426	O94967
LFTSPQRVYRNFHYR	UNC50	56	Q53HI1
KLLHYLARNFYNLRF	RYR3	4401	Q15413
QYQRLHFFLALYLAN	SPDYE1	201	Q8NFV5
AFRQNASLIRHRRYY	ZNF470	376	Q6ECI4
VFTYVQSLYNHLRRF	SMTNL2	446	Q2TAL5
EANFFIHRRLLYNRF	PRRG4	41	Q9BZD6
YHTVNRRYREFLNLQ	SNX19	576	Q92543
SYARQELQRLYRIFH	ZSCAN4	56	Q8NAM6
QARFSQRRYLLQHQF	ZNF785	206	A8K8V0
YSYLRQLFRNLFHRQ	CSNK1E	266	P49674
LFFQVRYHRYRLQLR	NAT8L	286	Q8N9F0