Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptidase activator activity

CASP8AP2 ACRBP APP PSME4 PCOLCE

4.79e-05701135GO:0016504
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO1D MYO1B MYO5C MYO15A

6.19e-05381134GO:0000146
GeneOntologyMolecularFunctionarachidonate 12(S)-lipoxygenase activity

ALOX12B ALOX15

1.89e-0441132GO:0004052
GeneOntologyCellularComponentDNA-dependent protein kinase complex

PRKDC UVRAG

2.87e-0451132GO:0070418
GeneOntologyCellularComponentmyosin complex

MYO1D MYO1B MYO5C MYO15A

2.93e-04591134GO:0016459
GeneOntologyCellularComponentGolgi-associated vesicle

SYNRG AFTPH PCLO APP ARCN1

3.88e-041141135GO:0005798
GeneOntologyCellularComponentintermediate-density lipoprotein particle

APOB APP

4.28e-0461132GO:0034363
GeneOntologyCellularComponentintercalated disc

ANK2 ANK3 DSC2 FHOD1

5.05e-04681134GO:0014704
GeneOntologyCellularComponentMLL1 complex

RUVBL2 MGA HCFC1

6.80e-04321133GO:0071339
GeneOntologyCellularComponentMLL1/2 complex

RUVBL2 MGA HCFC1

7.46e-04331133GO:0044665
GeneOntologyCellularComponentextracellular matrix

ADAMTSL1 ZAN FCGBP SEMA6D MUC17 VCAN SPARCL1 PRG4 HCFC1 CDON PCOLCE

8.57e-0465611311GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTSL1 ZAN FCGBP SEMA6D MUC17 VCAN SPARCL1 PRG4 HCFC1 CDON PCOLCE

8.79e-0465811311GO:0030312
DomainARM-type_fold

DCAF1 USP34 MROH2A APOB RIF1 PSME4 XPO6 FHOD1 PRKDC WDFY3 ARMC8

5.15e-0633911011IPR016024
DomainARM-like

DCAF1 MROH2A RIF1 PSME4 XPO6 FHOD1 PRKDC WDFY3 ARMC8

3.14e-052701109IPR011989
Domain-

DCAF1 RIF1 PSME4 XPO6 FHOD1 PRKDC WDFY3 ARMC8

5.09e-0522211081.25.10.10
DomainMyosin_head_motor_dom

MYO1D MYO1B MYO5C MYO15A

7.21e-05381104IPR001609
DomainMYOSIN_MOTOR

MYO1D MYO1B MYO5C MYO15A

7.21e-05381104PS51456
DomainMyosin_head

MYO1D MYO1B MYO5C MYO15A

7.21e-05381104PF00063
DomainMYSc

MYO1D MYO1B MYO5C MYO15A

7.21e-05381104SM00242
DomainTILa_dom

ZAN FCGBP

1.03e-0431102IPR025615
DomainTILa

ZAN FCGBP

1.03e-0431102PF12714
DomainLH2

PKDREJ ALOX12B ALOX15

1.52e-04181103SM00308
DomainFERM_M

TLN1 MYO15A EPB41L1 EPB41L2

1.54e-04461104PF00373
DomainFERM_central

TLN1 MYO15A EPB41L1 EPB41L2

1.97e-04491104IPR019748
DomainFERM_domain

TLN1 MYO15A EPB41L1 EPB41L2

1.97e-04491104IPR000299
Domain4_1_CTD

EPB41L1 EPB41L2

2.05e-0441102PF05902
DomainSAB

EPB41L1 EPB41L2

2.05e-0441102PF04382
DomainBand_4.1_C

EPB41L1 EPB41L2

2.05e-0441102IPR008379
DomainSAB_dom

EPB41L1 EPB41L2

2.05e-0441102IPR007477
DomainFERM_1

TLN1 MYO15A EPB41L1 EPB41L2

2.13e-04501104PS00660
DomainFERM_2

TLN1 MYO15A EPB41L1 EPB41L2

2.13e-04501104PS00661
DomainFERM_3

TLN1 MYO15A EPB41L1 EPB41L2

2.13e-04501104PS50057
DomainBand_41_domain

TLN1 MYO15A EPB41L1 EPB41L2

2.13e-04501104IPR019749
DomainB41

TLN1 MYO15A EPB41L1 EPB41L2

2.13e-04501104SM00295
Domain-

PKDREJ ALOX12B ALOX15

2.45e-042111032.60.60.20
DomainPLAT

PKDREJ ALOX12B ALOX15

2.45e-04211103PF01477
DomainPLAT/LH2_dom

PKDREJ ALOX12B ALOX15

2.45e-04211103IPR001024
DomainPLAT

PKDREJ ALOX12B ALOX15

2.45e-04211103PS50095
DomainDMAP_binding

DIP2A DIP2C

3.40e-0451102PF06464
DomainFERM_CS

TLN1 EPB41L1 EPB41L2

3.68e-04241103IPR019747
DomainLipOase_mml

ALOX12B ALOX15

5.08e-0461102IPR001885
DomainLIPOXYGENASE_1

ALOX12B ALOX15

5.08e-0461102PS00711
DomainLipOase_C

ALOX12B ALOX15

5.08e-0461102IPR013819
DomainDMAP1-bd

DIP2A DIP2C

5.08e-0461102IPR010506
DomainLIPOXYGENASE_2

ALOX12B ALOX15

5.08e-0461102PS00081
DomainLipOase_Fe_BS

ALOX12B ALOX15

5.08e-0461102IPR020833
DomainLipOase_CS

ALOX12B ALOX15

5.08e-0461102IPR020834
DomainLipoxygenase

ALOX12B ALOX15

5.08e-0461102PF00305
DomainLIPOXYGENASE_3

ALOX12B ALOX15

5.08e-0461102PS51393
DomainLipOase

ALOX12B ALOX15

5.08e-0461102IPR000907
DomainDMAP_binding

DIP2A DIP2C

5.08e-0461102SM01137
DomainDesmosomal_cadherin

DSC1 DSC2

7.08e-0471102IPR009122
DomainCadherin_pro

DSC1 DSC2

7.08e-0471102PF08758
DomainMyosin_TH1

MYO1D MYO1B

7.08e-0471102PF06017
DomainMyosin_TH1

MYO1D MYO1B

7.08e-0471102IPR010926
DomainTH1

MYO1D MYO1B

7.08e-0471102PS51757
DomainHEAT_REPEAT

MROH2A PSME4 PRKDC ARMC8

7.75e-04701104PS50077
DomainIQ

MYO1D MYO1B MYO5C MYO15A

8.17e-04711104PF00612
DomainCadherin_pro

DSC1 DSC2

9.40e-0481102SM01055
DomainCadherin_pro_dom

DSC1 DSC2

9.40e-0481102IPR014868
DomainFERM_N

TLN1 EPB41L1 EPB41L2

9.54e-04331103IPR018979
DomainFERM_N

TLN1 EPB41L1 EPB41L2

9.54e-04331103PF09379
DomainZU5

ANK2 ANK3

1.20e-0391102SM00218
DomainIQ

MYO1D MYO1B MYO5C MYO15A

1.34e-03811104SM00015
DomainVWC

ZAN FCGBP CHRD

1.44e-03381103SM00214
DomainZU5

ANK2 ANK3

1.50e-03101102PS51145
DomainFol_N

FCGBP SPARCL1

1.83e-03111102IPR003645
DomainFOLN

FCGBP SPARCL1

1.83e-03111102SM00274
DomainVWF_dom

ZAN FCGBP CHRD

1.93e-03421103IPR001007
DomainIQ_motif_EF-hand-BS

MYO1D MYO1B MYO5C MYO15A

1.97e-03901104IPR000048
DomainC8

ZAN FCGBP

2.18e-03121102PF08742
DomainTIL

ZAN FCGBP

2.18e-03121102PF01826
DomainZU5

ANK2 ANK3

2.18e-03121102PF00791
DomainZU5_dom

ANK2 ANK3

2.18e-03121102IPR000906
DomainIQ

MYO1D MYO1B MYO5C MYO15A

2.22e-03931104PS50096
DomainFA

EPB41L1 EPB41L2

2.57e-03131102PF08736
DomainFERM-adjacent

EPB41L1 EPB41L2

2.57e-03131102IPR014847
DomainUnchr_dom_Cys-rich

ZAN FCGBP

2.57e-03131102IPR014853
DomainC8

ZAN FCGBP

2.57e-03131102SM00832
DomainFA

EPB41L1 EPB41L2

2.57e-03131102SM01195
DomainIg-like_fold

EPHB2 ADAMTSL1 HLA-DMB PSG6 LRIT3 IGHG1 VCAN MYOM2 NFAT5 HCFC1 CDON

2.98e-0370611011IPR013783
DomainTIL_dom

ZAN FCGBP

2.99e-03141102IPR002919
DomainSEA

MUC16 MUC17

2.99e-03141102SM00200
Domain-

TLN1 EPB41L1 EPB41L2

3.01e-034911031.20.80.10
DomainFERM/acyl-CoA-bd_prot_3-hlx

TLN1 EPB41L1 EPB41L2

3.19e-03501103IPR014352
Domain-

MUC16 MUC17

3.43e-031511023.30.70.960
Domainp53-like_TF_DNA-bd

STAT4 MGA NFAT5

3.76e-03531103IPR008967
DomainVWF_type-D

ZAN FCGBP

3.91e-03161102IPR001846
DomainVWFD

ZAN FCGBP

3.91e-03161102PS51233
DomainVWD

ZAN FCGBP

3.91e-03161102SM00216
DomainVWD

ZAN FCGBP

3.91e-03161102PF00094
DomainFN3

EPHB2 LRIT3 MYOM2 HCFC1 CDON

4.78e-031851105SM00060
DomainVWC_out

ZAN FCGBP

5.51e-03191102SM00215
Domain-

EPHB2 ADAMTSL1 HLA-DMB PSG6 LRIT3 VCAN MYOM2 NFAT5 HCFC1 CDON

5.76e-03663110102.60.40.10
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZNF131 SYNRG AFTPH ANK2 DSC1 HSPH1 MYO1B CCT4 ARCN1 CEP170 RIF1 MAVS FHOD1 TLN1 ELF2 PRKDC PC HCFC1 EPB41L2 TP53BP1 SON

3.34e-129341142133916271
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

USP34 FAT4 ANK3 DSC2 LGR4 MUC16 CCT4 APOB ARCN1 TMEM263 RIF1 MAVS TMF1 PRKDC PC MGA EPB41L2 CDON

8.56e-117771141835844135
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PDE1C ANK2 ANK3 MYO1D PCLO HSPH1 CCT4 ITGA2 ARCN1 CEP170 DIP2A SLC24A2 IGHG1 VCAN TLN1 MAP7D2 SLC25A11 HADH PC DAGLA EPB41L1 EPB41L2 ARMC8

2.27e-1014311142337142655
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DCAF1 DSC1 HSPH1 MYO1B CCT4 RUVBL2 ARCN1 RIF1 PSME4 IGHG1 EIF4A1 FHOD1 TLN1 MCM3AP SLC25A11 PRKDC WDFY3 MGA ALOX12B EPB41L2 TP53BP1 SON

4.79e-1013531142229467282
Pubmed

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.

MYO1D HSPH1 MYO1B CCT4 APOB RUVBL2 IGHG1 EIF4A1 SLC25A11 PRKDC PC

5.51e-102441141128902428
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ANK2 ANK3 DSC2 HSPH1 MYO1B CCT4 RUVBL2 ARCN1 CEP170 TLN1 SLC25A11 PRKDC CRYBG3 HCFC1 EPB41L1 EPB41L2

1.49e-097081141639231216
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

HSPH1 MYO1B CCT4 RUVBL2 CEP170 RIF1 SLC25A11 PRKDC MGA HCFC1

3.35e-092211141029991511
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SYNRG ANK3 FNBP4 RUVBL2 ARCN1 CEP170 TLN1 SLC25A11 PRKDC PC MGA HCFC1 TP53BP1

3.33e-085491141338280479
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SYNRG ANK2 ANK3 PCLO CCT4 APP RUVBL2 ARCN1 C2CD2L CEP170 MAP7D2 SLC25A11 SPARCL1 CRYBG3 PC EPB41L1 EPB41L2 TP53BP1

3.39e-0811391141836417873
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 SYNRG SPG7 C2CD2 C6orf132 C2CD2L DIP2A PSME4 XPO6 TLN1 MCM3AP DIP2C PRKDC WDFY3 PC UVRAG HCFC1

1.24e-0711051141735748872
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

HIVEP1 DSC1 MYO1D PCLO HSPH1 MYO1B CCT4 APOB RUVBL2 ARCN1 RIF1 EIF4A1 TLN1 SLC25A11 PRKDC PC HCFC1 EPB41L2 ARMC8

1.92e-0714251141930948266
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 MYO1D MYO1B CEP170 RIF1 EIF4A1 TLN1 MCM3AP PRKDC HCFC1 EPB41L2 TP53BP1 SON

2.45e-076531141322586326
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MYO1D MYO1B CCT4 APP RUVBL2 ARCN1 MYO5C CEP170 RIF1 IGHG1 EIF4A1 TLN1 PRKDC MGA EPB41L2 SON

2.46e-0710241141624711643
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

SYNRG ZHX2 CEP170 MAVS FHOD1 TLN1 ELF2 PC MGA HCFC1 EPB41L2

2.57e-074441141134795231
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SYNRG HIVEP1 AFTPH FNBP4 RFX7 RIF1 XPO6 FHOD1 ELF2 PRKDC PRG4 EPB41L2 TP53BP1 SON

2.61e-077741141415302935
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ANK3 PCLO HSPH1 MYO1B CCT4 RUVBL2 ARCN1 EIF4A1 TLN1 SLC25A11 PRKDC MYO15A PC HYDIN

4.30e-078071141430575818
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

ADAMTSL1 ANK2 DSC1 ANK3 MYO1D APP CEP170 EIF4A1 FHOD1

4.90e-07288114938496616
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

HSPH1 CCT4 RUVBL2 MYO5C PSME4 EIF4A1 SLC25A11 PRKDC

5.10e-07211114817314511
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

HSPH1 RUVBL2 RIF1 EIF4A1 SLC25A11 PRKDC MGA NFAT5 HCFC1 EPB41L2 TP53BP1 SON

5.15e-075831141229844126
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 CASP8AP2 C2CD2L XPO6 TLN1 DIP2C WDFY3 DAGLA

8.28e-07225114812168954
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SYNRG AFTPH MYO1D HSPH1 CCT4 RUVBL2 ARCN1 MAVS TLN1 MAP7D2 CEP295 SLC25A11 PC MGA

8.30e-078531141428718761
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 PCLO HSPH1 ARCN1 DIP2A TLN1 MCM3AP CHRD CEP295 PRKDC PWWP3B PRG4 EPB41L2

9.38e-077361141329676528
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DCAF1 ZHX2 C2CD2L SEMA6D TLN1 MCM3AP FNIP1 NFAT5 EPB41L1 SON

9.96e-074071141012693553
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

USP34 ADAMTSL1 PCLO MCM3AP MGA ZNF292

1.34e-0610511469628581
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

DSC1 MYO1D HSPH1 MYO1B CCT4 ITGA2 RUVBL2 ARCN1 SLC25A11 PRKDC ALOX12B TP53BP1

1.53e-066471141226618866
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCAF1 CASP8AP2 ZNF131 AFTPH ANK2 ANK3 DSC2 HSPH1 FNBP4 APP TMEM263 DIP2A TLN1 MAP7D2 CRYBG3 EPB41L1 EPB41L2 TP53BP1

1.67e-0614871141833957083
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

EPHB2 USP34 HLA-DMB HSPH1 LGR4 APOB C2CD2 RIF1 MAVS MCM3AP TMF1 GNAL PRKDC WDFY3 PC

2.08e-0610611141533845483
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

EPHB2 DSC1 HSPH1 CCT4 RUVBL2 ARCN1 CEP170 FCGBP MAVS EIF4A1 TLN1 SLC25A11 PRKDC PC HCFC1 TP53BP1 SON

2.34e-0613671141732687490
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

ANK2 HSPH1 FNBP4 MYO1B APOB RUVBL2 ARCN1 TMEM263 CEP170 RIF1 TLN1 MCM3AP SLC25A11 PC HCFC1 EPB41L2 SON

2.43e-0613711141736244648
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

DSC2 HSPH1 C2CD2 ARCN1 TMEM263 C2CD2L CEP170 MAVS TLN1 TMF1 HCFC1

2.83e-065681141137774976
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

DSC1 HSPH1 CCT4 IGHG1 EIF4A1 PRKDC PC MGA HCFC1

2.88e-06357114937059091
Pubmed

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.

DCAF1 HSPH1 CCT4 RUVBL2 RIF1 XPO6 EPB41L1 EPB41L2

3.22e-06270114824366813
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

HSPH1 FNBP4 CCT4 RUVBL2 ARCN1 CEP170 RIF1 IGHG1 EIF4A1 FHOD1 TLN1 SLC25A11 PRKDC PC HCFC1 EPB41L2 SON

3.71e-0614151141728515276
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DCAF1 USP34 DSC2 LGR4 APP RUVBL2 C2CD2L CEP170 MCM3AP CEP295 SLC25A11 WDFY3 CRYBG3 MGA SON

3.85e-0611161141531753913
Pubmed

Human transcription factor protein interaction networks.

ZNF131 HIVEP1 MYO1D HSPH1 MYO1B CCT4 RFX7 ZHX2 RUVBL2 STAT4 MYO5C RIF1 ELF2 SLC25A11 MGA HCFC1 TP53BP1

4.23e-0614291141735140242
Pubmed

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

RUVBL2 PRKDC CCDC180 HCFC1 TP53BP1 SON

4.26e-06128114623858473
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP34 ANK2 ANK3 HSPH1 APP ARCN1 FAN1 DIP2A EIF4A1 PKNOX1 SPARCL1 PRKDC WDFY3 PC ZNF292 ARMC8

4.71e-0612851141635914814
Pubmed

A human MAP kinase interactome.

CASP8AP2 HIVEP1 ANK3 RIF1 CSN1S1 FHOD1 MCM3AP PRKDC MGA EPB41L2

4.82e-064861141020936779
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

MYO1D HSPH1 CCT4 RUVBL2 TMEM263 CEP170 EIF4A1 SLC25A11 PRKDC

5.08e-06383114929331416
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SYNRG HIVEP1 AFTPH DSC2 RFX7 C6orf132 CEP170 FNIP1 CRYBG3 PC UVRAG EPB41L1 EPB41L2

5.21e-068611141336931259
Pubmed

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

FAT4 ANK3 PCLO

5.55e-0611114320351715
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

DSC1 HSPH1 CCT4 RUVBL2 ARCN1 EIF4A1 FHOD1 TLN1 SLC25A11 PRKDC HADH EPB41L2 ZNF292

6.42e-068781141337223481
Pubmed

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.

CCT4 RUVBL2 EIF4A1 PRKDC MGA

6.43e-0679114526446488
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

AFTPH HSPH1 RIF1 MAVS TMF1 HCFC1 EPB41L1 EPB41L2 TP53BP1 SON

6.51e-065031141016964243
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

MYO1D FNBP4 MYO1B CCT4 RUVBL2 RIF1 EIF4A1 TLN1 TP53BP1 SON

6.86e-065061141030890647
Pubmed

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.

AFTPH APP RUVBL2 ARCN1 MAP7D2 SLC25A11

7.43e-06141114632322062
Pubmed

Gene expression in the developing mouse retina by EST sequencing and microarray analysis.

CASP8AP2 LGR4 CCT4 RFX7 CEP295 DAGLA

7.73e-06142114611812828
Pubmed

New insights into potential functions for the protein 4.1 superfamily of proteins in kidney epithelium.

APP C2CD2L EPB41L1

9.58e-0613114316368544
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PCLO DIP2A XPO6 WDFY3 ZNF292

1.03e-0587114512465718
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

EPHB2 USP34 PDE1C MUC16 APOB RUVBL2 CEP170 DIP2A EPB41L2

1.06e-05420114928065597
Pubmed

Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development.

PRKDC ALOX15

1.07e-052114223437231
Pubmed

Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog.

DIP2A DIP2C

1.07e-052114212137943
Pubmed

53BP1-RIF1: sculpting the DNA repair focus in 3D.

RIF1 TP53BP1

1.07e-052114231792447
Pubmed

cAMP Signaling-Mediated Phosphorylation of Diacylglycerol Lipase α Regulates Interaction With Ankyrin-G and Dendritic Spine Morphology.

ANK3 DAGLA

1.07e-052114234099188
Pubmed

Identification and characterization of TMEM24 family genes in silico.

C2CD2 C2CD2L

1.07e-052114215289880
Pubmed

STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease.

STAT4 PRKDC

1.07e-052114218802110
Pubmed

The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression.

EPB41L1 EPB41L2

1.07e-052114219225127
Pubmed

Aftiphilin and gamma-synergin are required for secretagogue sensitivity of Weibel-Palade bodies in endothelial cells.

SYNRG AFTPH

1.07e-052114218815278
Pubmed

Myosin 1b functions as an effector of EphB signaling to control cell repulsion.

EPHB2 MYO1B

1.07e-052114226195670
Pubmed

Amyloid-beta colocalizes with apolipoprotein B in absorptive cells of the small intestine.

APOB APP

1.07e-052114219845970
Pubmed

53BP1/RIF1 signaling promotes cell survival after multifractionated radiotherapy.

RIF1 TP53BP1

1.07e-052114231822909
Pubmed

Differential synthesis of type 1 and type 2 desmocollin mRNAs in human stratified epithelia.

DSC1 DSC2

1.07e-05211428507556
Pubmed

The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress.

RIF1 TP53BP1

1.07e-052114233141022
Pubmed

A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell-cell contacts.

C2CD2 C2CD2L

1.07e-052114239158698
Pubmed

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

RIF1 TP53BP1

1.07e-052114223333305
Pubmed

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

ANK2 ANK3

1.07e-052114211781319
Pubmed

Structural basis of diverse membrane target recognitions by ankyrins.

ANK2 ANK3

1.07e-052114225383926
Pubmed

Sublethal doses of β-amyloid peptide abrogate DNA-dependent protein kinase activity.

APP PRKDC

1.07e-052114222139836
Pubmed

Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma.

RUVBL2 PRKDC

1.07e-052114225875766
Pubmed

15-lipoxygenase-1 activates tumor suppressor p53 independent of enzymatic activity.

PRKDC ALOX15

1.07e-052114218785202
Pubmed

53BP1 regulates DSB repair using Rif1 to control 5' end resection.

RIF1 TP53BP1

1.07e-052114223306437
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

USP34 CCT4 EIF4A1 VCAN PRKDC EPB41L2 TP53BP1

1.31e-05235114730258100
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

DSC1 CCT4 RUVBL2 RIF1 PRKDC MGA

1.32e-05156114637108203
Pubmed

A gene expression map of human chromosome 21 orthologues in the mouse.

APP C2CD2 DIP2A MCM3AP PKNOX1 SON

1.42e-05158114612466855
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MYO1D HSPH1 MYO1B CCT4 APP RFX7 RUVBL2 ARCN1 EIF4A1 TLN1 SLC25A11 PRKDC MGA NFAT5 HCFC1

1.44e-0512471141527684187
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZNF131 HIVEP1 FNBP4 CEP170 RIF1 EIF4A1 ELF2 PRKDC PC MGA HCFC1 TP53BP1 SON

1.55e-059541141336373674
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

SYNRG ANK2 ANK3 CCT4 APP RUVBL2 CEP170 EIF4A1 TLN1 EPB41L1

1.60e-055581141035063084
Pubmed

Human chromosome 21 gene expression atlas in the mouse.

APP C2CD2 DIP2A MCM3AP PKNOX1 SON

1.70e-05163114612466854
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

MYO1D HSPH1 MYO1B CCT4 RUVBL2 IGHG1 EIF4A1 SLC25A11 PRKDC PC

1.78e-055651141033567341
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

ANK2 HSPH1 CCT4 ARCN1 EIF4A1 TLN1 SLC25A11 PRKDC EPB41L2

1.80e-05449114931732153
Pubmed

The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.

ZNF131 ELF2 HCFC1

1.86e-0516114320805357
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

HSPH1 CCT4 TLN1 PRKDC HADH HCFC1 TP53BP1 SON

1.87e-05344114830333137
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

CCT4 RUVBL2 ARCN1 EIF4A1 SLC25A11 PRKDC PC HCFC1 EPB41L2 TP53BP1 SON

2.11e-057041141129955894
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF131 HIVEP1 APP RFX7 ZHX2 MCM3AP ELF2 MGA

2.16e-05351114838297188
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

DCAF1 DSC1 HSPH1 MYO1B CCT4 RUVBL2 RIF1 EIF4A1 PRKDC PC HCFC1 TP53BP1 SON

2.25e-059891141336424410
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

HSPH1 CCT4 CEP170 TLN1 PRKDC HCFC1 EPB41L2

2.27e-05256114733397691
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

DSC2 HLA-DMB APOB APP FCGBP SPARCL1 PRG4

2.33e-05257114716335952
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

USP34 CASP8AP2 SYNRG HIVEP1 MYO1D MYO1B RUVBL2 MCM3AP CRYBG3 TP53BP1

2.49e-055881141038580884
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

DSC1 MYO1B CCT4 ARCN1 EIF4A1 FHOD1 TLN1 PRKDC SON

2.89e-05477114931300519
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

DCAF1 DSC1 MYO1D CCT4 RUVBL2 IGHG1 PRKDC

2.90e-05266114719380743
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

AFTPH HSPH1 CCT4 APP ZHX2 C6orf132 C2CD2L RIF1 EIF4A1 TLN1 TMF1 SLC25A11 EPB41L1 EPB41L2 SON ARMC8

3.09e-0514971141631527615
Pubmed

Regulation of AMPA receptor GluR1 subunit surface expression by a 4. 1N-linked actin cytoskeletal association.

EPB41L1 EPB41L2

3.19e-053114211050113
Pubmed

Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest.

DCAF1 TP53BP1

3.19e-053114220824083
Pubmed

GANP regulates the choice of DNA repair pathway by DNA-PKcs interaction in AID-dependent IgV region diversification.

MCM3AP PRKDC

3.19e-053114224808370
Pubmed

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

ANK2 ANK3

3.19e-053114215611082
Pubmed

HIV-1 Vpr and G2 cell cycle arrest.

DCAF1 TP53BP1

3.19e-053114221526938
Pubmed

CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.

DIP2A DIP2C

3.19e-053114217236128
Pubmed

Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance.

STAT4 PRKDC

3.19e-053114211067913
Pubmed

Islet antigen-specific Th17 cells can induce TNF-α-dependent autoimmune diabetes.

STAT4 PRKDC

3.19e-053114224446517
Pubmed

Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry.

USP34 GVINP1

3.19e-053114217203969
InteractionNAA40 interactions

ZNF131 SYNRG AFTPH ANK2 DSC1 HSPH1 MYO1B CCT4 ARCN1 CEP170 RIF1 MAVS FHOD1 TLN1 ELF2 PRKDC PC HCFC1 EPB41L2 TP53BP1 SON

1.03e-0797811321int:NAA40
InteractionKCNA3 interactions

ANK2 ANK3 DSC2 MYO1D HSPH1 MYO1B CCT4 RUVBL2 ARCN1 MYO5C CEP170 EIF4A1 TLN1 SLC25A11 PRKDC CRYBG3 HCFC1 EPB41L1 EPB41L2

3.58e-0787111319int:KCNA3
InteractionFLOT1 interactions

ANK2 ANK3 DSC2 MYO1D PCLO MYO1B CCT4 APP STAT4 ELF2 SLC25A11 CRYBG3 EPB41L1 EPB41L2

4.40e-0747511314int:FLOT1
InteractionTOP3B interactions

USP34 SYNRG SPG7 MYO1D MYO1B APOB APP C2CD2 C6orf132 C2CD2L DIP2A PSME4 XPO6 EIF4A1 TLN1 MCM3AP DIP2C SLC25A11 PRKDC WDFY3 PC UVRAG HCFC1 TP53BP1

1.67e-06147011324int:TOP3B
InteractionNUP43 interactions

DCAF1 USP34 CASP8AP2 ZNF131 HIVEP1 DSC1 ZHX2 RIF1 MAVS MCM3AP ELF2 MGA HCFC1 SON ZNF292

2.18e-0662511315int:NUP43
InteractionKCTD13 interactions

PDE1C ANK2 ANK3 MYO1D PCLO HSPH1 CCT4 ITGA2 ARCN1 CEP170 DIP2A SLC24A2 VCAN TLN1 MAP7D2 SLC25A11 HADH PC DAGLA EPB41L1 EPB41L2 ARMC8

8.46e-06139411322int:KCTD13
InteractionNEXN interactions

ANK3 MYO1D LGR4 MYO1B APOB MYO5C

1.23e-05911136int:NEXN
InteractionUCHL5 interactions

DSC1 HSPH1 CCT4 APOB APP RUVBL2 PSME4 IGHG1 EIF4A1 FHOD1

1.26e-0531911310int:UCHL5
InteractionEPB41L4A interactions

ANK3 DSC2 MYO1D MYO1B CCT4 APP EPB41L1

1.40e-051401137int:EPB41L4A
InteractionSIRT7 interactions

DCAF1 USP34 MYO1D MYO1B APP CEP170 RIF1 EIF4A1 TLN1 MCM3AP PRKDC HCFC1 EPB41L2 TP53BP1 SON

1.76e-0574411315int:SIRT7
InteractionMYH9 interactions

DCAF1 HIVEP1 HSPH1 LGR4 MYO1B APOB RUVBL2 C2CD2 ARCN1 MYO5C TLN1 PKNOX1 MYOM2 CCDC180 EPB41L2

2.06e-0575411315int:MYH9
InteractionFLCN interactions

CCT4 APP FNIP1 WDFY3 CCDC180 TP53BP1

2.11e-051001136int:FLCN
InteractionASXL2 interactions

HSPH1 CCT4 APOB APP RUVBL2 EIF4A1 ELF2 PRKDC HCFC1

2.64e-052771139int:ASXL2
InteractionELF2 interactions

EPHB2 ZNF131 HIVEP1 APP ZHX2 ELF2 MGA

2.83e-051561137int:ELF2
InteractionYAP1 interactions

ANK3 MYO1D HSPH1 FNBP4 MYO1B CCT4 RUVBL2 CEP170 EIF4A1 TLN1 SLC25A11 PRKDC PC MGA NFAT5 UVRAG HCFC1 EPB41L2

3.71e-05109511318int:YAP1
InteractionTRIM40 interactions

LGR4 APP MAVS

4.71e-05131133int:TRIM40
InteractionPLA2G4C interactions

EPHB2 APP PRKDC

4.71e-05131133int:PLA2G4C
InteractionRPA4 interactions

USP34 APP RUVBL2 CEP170 RIF1 PSME4 TLN1 SLC25A11 HCFC1 EPB41L2 SON

4.77e-0545211311int:RPA4
InteractionSETD1A interactions

RUVBL2 ELF2 PRKDC HCFC1 EPB41L1 EPB41L2 TP53BP1

4.90e-051701137int:SETD1A
InteractionITGB3 interactions

HSPH1 APP TLN1 PRKDC HCFC1 TP53BP1 SON

4.90e-051701137int:ITGB3
InteractionARL5A interactions

CCT4 APP MAVS TMF1 PC EPB41L2

5.38e-051181136int:ARL5A
InteractionYWHAG interactions

SYNRG HIVEP1 AFTPH DSC2 HSPH1 LGR4 APP RFX7 RUVBL2 C6orf132 C2CD2L CEP170 IGHG1 FNIP1 PRKDC UVRAG EPB41L1 EPB41L2 SON

6.22e-05124811319int:YWHAG
InteractionC11orf52 interactions

ANK3 DSC2 MYO1D MYO1B CCT4 APP DIP2A EPB41L1 EPB41L2

6.48e-053111139int:C11orf52
InteractionAGR2 interactions

ZNF131 ANK3 PCLO HSPH1 MYO1B CCT4 APP RUVBL2 ARCN1 EIF4A1 TLN1 SLC25A11 PRKDC MYO15A PC HYDIN

6.49e-0593411316int:AGR2
InteractionNRSN1 interactions

DSC2 LGR4 APP C2CD2L FCGBP IGHG1 RELT

6.79e-051791137int:NRSN1
InteractionGRWD1 interactions

HSPH1 MYO1B CCT4 RUVBL2 CEP170 RIF1 SLC25A11 PRKDC MGA HCFC1

6.94e-0539011310int:GRWD1
InteractionRFWD3 interactions

CEP170P1 LGR4 CCT4 APP CEP170

8.72e-05801135int:RFWD3
InteractionGABPA interactions

APP FCGBP IGHG1 ELF2 HCFC1 ALOX12B

9.22e-051301136int:GABPA
InteractionTRIM52 interactions

APP MYO5C DIP2A MAP7D2 CEP295 MGA

1.05e-041331136int:TRIM52
InteractionAATK interactions

SYNRG AFTPH HSPH1 APOB DIP2A SLC25A11 PRKDC

1.12e-041941137int:AATK
InteractionPPIA interactions

ZNF131 AFTPH ANK3 APP CEP170 RIF1 MAVS EIF4A1 FHOD1 KLHL15 CRYBG3 UVRAG HCFC1 TP53BP1 ARMC8

1.31e-0488811315int:PPIA
InteractionBTF3 interactions

ANK2 ANK3 MYO1D HSPH1 MYO1B CCT4 APP RUVBL2 TMEM263 CEP170 IGHG1 EIF4A1 PRKDC NFAT5

1.53e-0479911314int:BTF3
InteractionYWHAQ interactions

SYNRG AFTPH DSC2 HSPH1 APP RFX7 ZHX2 RUVBL2 C6orf132 CEP170 IGHG1 TLN1 PRKDC PC UVRAG EPB41L1 EPB41L2

1.61e-04111811317int:YWHAQ
InteractionARL4D interactions

USP34 DSC2 APP RIF1 PC MGA

1.74e-041461136int:ARL4D
InteractionRNF123 interactions

FAT4 PCLO HSPH1 APP ARCN1 DIP2A TLN1 MCM3AP CHRD CEP295 PRKDC PWWP3B PRG4 EPB41L2

2.10e-0482411314int:RNF123
InteractionZFPL1 interactions

ANK3 DSC2 MYO1B ARCN1 C2CD2L MAVS IGHG1 TMF1 EPB41L1 EPB41L2

2.15e-0444811310int:ZFPL1
InteractionEPHB2 interactions

EPHB2 ANK2 ANK3 APP DIP2A ELF2 PRKDC

2.18e-042161137int:EPHB2
InteractionPML interactions

USP34 CASP8AP2 SYNRG MYO1D APP ZHX2 CEP170 MAVS FHOD1 TLN1 ELF2 PC HCFC1 EPB41L2 TP53BP1

2.24e-0493311315int:PML
InteractionTFCP2L1 interactions

RUVBL2 RIF1 PRKDC MGA HCFC1

2.38e-04991135int:TFCP2L1
InteractionYY1 interactions

ZNF131 HIVEP1 APP ZHX2 RUVBL2 RIF1 ELF2 PRKDC MGA HCFC1

2.39e-0445411310int:YY1
InteractionRBX1 interactions

DCAF1 HSPH1 APP RUVBL2 MYO5C EIF4A1 KLHL15 PRKDC PC UVRAG SON

3.02e-0455811311int:RBX1
InteractionKLF3 interactions

ZNF131 HIVEP1 APP RFX7 ZHX2 ELF2 MGA

3.03e-042281137int:KLF3
InteractionHCFC1R1 interactions

APP HCFC1

3.08e-0451132int:HCFC1R1
InteractionTNKS interactions

SPG7 CEP170P1 CEP170 MAVS EIF4A1

3.13e-041051135int:TNKS
Cytoband21q22.3

C2CD2 DIP2A MCM3AP PKNOX1

3.03e-04128114421q22.3
CytobandEnsembl 112 genes in cytogenetic band chr4q25

ANK2 LRIT3 HADH

1.55e-03911143chr4q25
Cytoband18q12.1

DSC1 DSC2

1.91e-0326114218q12.1
CytobandEnsembl 112 genes in cytogenetic band chr21q22

C2CD2 DIP2A MCM3AP PKNOX1 SON

2.57e-033771145chr21q22
Cytoband2p15

USP34 CCT4

2.71e-033111422p15
Cytoband7q22

ZAN PCOLCE

4.05e-033811427q22
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

TLN1 MYO15A EPB41L1 EPB41L2

5.73e-05507641293
GeneFamilyErythrocyte membrane protein band 4.1|FERM domain containing

EPB41L1 EPB41L2

1.04e-044762951
GeneFamilyArachidonate lipoxygenases

ALOX12B ALOX15

2.59e-046762407
GeneFamilyDesmosomal cadherins

DSC1 DSC2

3.61e-0477621188
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PCLO C2CD2 UVRAG

4.61e-0436763823
GeneFamilyMyosins, class I

MYO1D MYO1B

4.80e-0487621097
GeneFamilyCD molecules|Mucins

MUC16 MUC17

3.48e-0321762648
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ADAMTSL1 LRIT3 MYOM2 CDON

4.73e-03161764593
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

EPHB2 USP34 HIVEP1 MYO1B APP ZHX2 C2CD2 CEP170 RIF1 PSME4 XPO6 WDFY3 CRYBG3 UVRAG TP53BP1 SON ZNF292

1.79e-0785611417M4500
CoexpressionNAKAYA_B_CELL_FLUMIST_AGE_18_50YO_7DY_UP

ZNF131 ANK3 CCT4 RUVBL2 CEP170 MAVS GVINP1 IGHG1 PKNOX1 ELF2 SLC25A11 ARMC8

1.14e-0647511412M40979
CoexpressionGSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN

HLA-DMB HSPH1 CCT4 STAT4 CEP170 EIF4A1 TMF1

2.63e-051981147M6089
CoexpressionGSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN

USP34 C2CD2 MYO5C FAN1 MAVS TMF1 MYOM2

2.71e-051991147M9567
CoexpressionKYNG_WERNER_SYNDROM_UP

ITGA2 GNAL HADH

2.82e-05141143M1996
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PDE1C ZAN MROH2A PCLO APOB SLC24A2 MYOM2 MYO15A HYDIN

4.82e-11184114102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PDE1C ZAN MROH2A PCLO APOB SLC24A2 MYOM2 MYO15A HYDIN

4.82e-1118411410ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PDE1C ZAN MROH2A PCLO APOB SLC24A2 MYOM2 MYO15A HYDIN

4.82e-11184114102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK3 MYO1D PCLO MUC16 ITGA2 APP C6orf132 SPARCL1 EPB41L1 ALOX15

1.09e-1020011410ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANK3 MYO1D PCLO ITGA2 APP C6orf132 SPARCL1 EPB41L1 ALOX15

2.45e-09200114997f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO RIF1 SLC24A2 FNIP1 HADH PC MGA SON

4.01e-0819511483e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO RIF1 SLC24A2 FNIP1 HADH PC MGA SON

4.01e-0819511487796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ANK2 MYO1B APP VCAN SPARCL1 EPB41L2 CDON PCOLCE

4.69e-08199114840de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

GPR155 PDE1C ANK2 ANK3 SEMA6D DIP2C EPB41L2

2.63e-07168114788c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 HLA-DMB PCLO SLC24A2 HADH PC SON

5.61e-071881147a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 LGR4 MYO1B ITGA2 MYO5C SEMA6D EPB41L1

5.82e-071891147e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP34 SYNRG PRKDC WDFY3 CRYBG3 MGA SON

6.69e-071931147abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 MYO1D LGR4 APP C6orf132 VCAN EPB41L1

6.69e-071931147263d185af6ed80e639f864e4966268e0862c61dc
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 ADAMTSL1 ANK2 ADGRG4 VCAN SPARCL1 EPB41L2

7.17e-071951147f54bc4454270ff06e85596f98199372b50d0179f
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

USP34 ANK3 MYO1D RFX7 ZHX2 DIP2C WDFY3

8.22e-07199114794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ADAMTSL1 ANK2 VCAN SPARCL1 EPB41L2 PCOLCE

8.50e-0720011470c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR155 ZHX2 C2CD2L DIP2C TMEM108 NFAT5

5.99e-061751146711ace94fa9a763c6ae48171a690953f25deebe4
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTSL1 MUC16 C6orf132 TMEM108 PRG4 CDON

6.60e-0617811461e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 PDE1C MYO1B STAT4 SEMA6D GNAL

6.81e-061791146c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 ANK3 TMEM108 SPARCL1 CDON PCOLCE

8.22e-061851146f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB LRIT3 CRYBG3 RELT UVRAG EPB41L2

8.22e-061851146405bd4ba7ca7f7b625c49f1313ff946509e17c13
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 ANK3 TMEM108 SPARCL1 CDON PCOLCE

8.22e-06185114640e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 ANK3 TMEM108 SPARCL1 CDON PCOLCE

8.22e-0618511465f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB LRIT3 CRYBG3 RELT UVRAG EPB41L2

8.22e-0618511462aa5e9f6f167d27317a01d22392b59512333fa64
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO1B VCAN TMEM108 SPARCL1 EPB41L2 PCOLCE

8.74e-061871146a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 MYO1B ITGA2 MYO5C SEMA6D EPB41L1

8.74e-061871146f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 MYO1B ITGA2 MYO5C SEMA6D TMEM108

9.29e-061891146975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 MYO1B ITGA2 MYO5C SEMA6D TMEM108

9.29e-0618911467eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

DSC2 PCLO MUC16 PWWP3B PRG4 ALOX15

9.57e-061901146d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ADAMTSL1 ANK3 CSN1S1 SPARCL1 PRG4 EPB41L1

9.57e-061901146b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 DSC2 MYO1B APOB PSME4 TMF1

9.86e-06191114660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 HLA-DMB PCLO SLC24A2 HADH PC

9.86e-0619111463387b95a3f2445c672d407922fdce3a91eabaef8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 DSC2 MYO1B APOB PSME4 TMF1

9.86e-06191114609db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 DSC2 MYO1B APOB PSME4 TMF1

9.86e-061911146973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTSL1 VCAN CHRD SPARCL1 CDON PCOLCE

1.02e-0519211467b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

FAT4 ADAMTSL1 ANK2 SPARCL1 EPB41L2 PCOLCE

1.02e-051921146a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellFibroblasts-CD55+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ADAMTSL1 ANK3 SEMA6D SPARCL1 EPB41L1 CDON

1.05e-0519311468f4bf9a2fbedae35432dad96730b00c70185874c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 LGR4 APP C6orf132 VCAN EPB41L1

1.05e-05193114680e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 LGR4 APP C6orf132 VCAN EPB41L1

1.05e-051931146b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 ADAMTSL1 ANK2 SPARCL1 CDON PCOLCE

1.05e-0519311469ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

ANK3 PCLO C6orf132 SEMA6D VCAN PWWP3B

1.05e-0519311469152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPHB2 FAT4 ANK2 EPB41L2 CDON PCOLCE

1.08e-051941146439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell(5)_Fibroblasts-(5)_Fibroblast-J_(Lipofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

ANK2 DSC2 PCLO MUC16 ALOX15 CDON

1.08e-051941146784b15119c91ace33d34bfb3d68c182566a3e9a8
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAMTSL1 DSC2 MUC16 WDFY3 MYO15A CDON

1.11e-051951146d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAMTSL1 DSC2 MUC16 WDFY3 MYO15A CDON

1.11e-05195114619853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNRG ANK3 STAT4 GVINP1 PRKDC ZNF292

1.14e-0519611464a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell368C|World / Donor, Lineage, Cell class and subclass (all cells)

ANK2 HSPH1 IGHG1 VCAN SPARCL1 PCOLCE

1.18e-051971146f41211923938e5d7bfe6bf24f604ab386f17ef10
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT4 VCAN TMEM108 SPARCL1 EPB41L2 PCOLCE

1.21e-05198114617dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell15-Distal-Mesenchymal-Mesenchyme_RSPO2+|Distal / Age, Tissue, Lineage and Cell class

FHOD1 VCAN TMEM108 SPARCL1 EPB41L2 PCOLCE

1.21e-051981146e87d1fe2befbd32b0c723ab43b9de95495ea3ee3
ToppCellstromal_cell|World / Lineage and Cell class

ANK2 APOB SEMA6D TMEM108 SPARCL1 PCOLCE

1.25e-051991146507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCellstromal_cell-stromal_cell|World / Lineage and Cell class

ANK2 APOB SEMA6D TMEM108 SPARCL1 PCOLCE

1.25e-05199114674262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCellwk_08-11-Mesenchymal-Fibroblast-intermediate_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FHOD1 VCAN TMEM108 SPARCL1 EPB41L2 PCOLCE

1.25e-051991146f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCellFibroblasts-CD34+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ANK2 VCAN SPARCL1 GNAL EPB41L2 PCOLCE

1.25e-05199114613ff7409e200a0b46cdb7924d15ef33639693622
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT4 VCAN TMEM108 SPARCL1 EPB41L2 PCOLCE

1.25e-051991146a09292de4c4447b8eee55d401808e43b817321cc
ToppCellILEUM-inflamed-(8)_Fibroblasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FAT4 ANK2 SEMA6D VCAN SPARCL1 CRYBG3

1.25e-0519911463a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ANK2 SEMA6D VCAN SPARCL1 CRYBG3 EPB41L2

1.25e-051991146615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANK3 MUC16 MYO1B C6orf132 MYO5C ALOX15

1.28e-052001146d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK3 MUC16 ITGA2 APP C6orf132 MYO5C

1.28e-052001146d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FAT4 ITGA2 SPARCL1 PRG4 EPB41L2 PCOLCE

1.28e-052001146aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellBronchus_Control_(B.)-Stromal-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FAT4 ANK2 CHRD SPARCL1 PRG4 PCOLCE

1.28e-05200114669b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FAT4 ITGA2 SPARCL1 PRG4 EPB41L2 PCOLCE

1.28e-052001146a510deaada669e690329183e18df02870bd204b3
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

ANK2 VCAN CHRD PRG4 EPB41L2 PCOLCE

1.28e-052001146f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron|GW26 / Sample Type, Dataset, Time_group, and Cell type.

ANK2 ANK3 APP CEP170 TMEM108 GNAL

1.28e-0520011465b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTSL1 ANK2 ADGRG4 VCAN SPARCL1 EPB41L2

1.28e-05200114674e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellTracheal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 VCAN SPARCL1 PRG4 EPB41L2 PCOLCE

1.28e-052001146920e6036c0a9c0089d0d898673daf9dd9d7279fc
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAT4 ITGA2 SPARCL1 PRG4 EPB41L2 PCOLCE

1.28e-052001146dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Ebf1_(Anterior_pretectal_nucleus_(APT))-|Thalamus / BrainAtlas - Mouse McCarroll V32

APOB LRIT3 STAT4 MYO15A

1.39e-05571144ef44602342511a9f90c93463628ad8b154cb26fb
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Ebf1_(Anterior_pretectal_nucleus_(APT))|Thalamus / BrainAtlas - Mouse McCarroll V32

APOB LRIT3 STAT4 MYO15A

1.39e-05571144a3dc14f7a63cc70b2789770644e0b9453426c6f9
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|343B / Donor, Lineage, Cell class and subclass (all cells)

EPHB2 ZNF131 PSME4 CEP295 CCDC180

2.37e-0513311458ff1cf0ea1fc33fe8384c0e65c1ee1853b25a2ae
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ndnf_(medial_geniculate_nucleus,_ventral_part_(MGV)?_Or_State?)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DSC2 PKDREJ PRG4 ALOX12B

3.92e-05741144c68b00cf7d2cec7951b78e2c6710d7770b02566a
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ndnf_(medial_geniculate_nucleus,_ventral_part_(MGV)?_Or_State?)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DSC2 PKDREJ PRG4 ALOX12B

3.92e-05741144bad24c9251ef44c05f3390073732a467aaeefe1e
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ndnf_(medial_geniculate_nucleus,_ventral_part_(MGV)?_Or_State?)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DSC2 PKDREJ PRG4 ALOX12B

3.92e-05741144195fd37345a394c0b60f713bedadf6fd08dc050c
ToppCellCOVID-19_Severe-multiplets|COVID-19_Severe / disease group, cell group and cell class

PKDREJ DIP2A IGHG1 HYDIN ALOX15

4.50e-051521145451745151322c2fcea22dbb3dba681e12634a510
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

STAT4 DIP2A IGHG1 MYOM2 ALOX15

5.09e-051561145afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellCOVID-19-lung-Mesothelial|lung / Disease (COVID-19 only), tissue and cell type

MUC16 SEMA6D PRG4 ALOX15 CDON

5.09e-051561145e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCellsevere_influenza-CD4+_T_naive|World / disease group, cell group and cell class (v2)

DSC1 ANK3 C6orf132 MYO15A ALOX12B

5.41e-0515811458ab3d8a9b7a1daa890d76dde1d6182af40b70021
ToppCellCOVID-19_Severe-NK_CD56bright|COVID-19_Severe / disease group, cell group and cell class

SYNRG FAT4 PDE1C STAT4 DIP2A

5.57e-0515911459e2067f0d76769717f7048dab505fadd36bbb83e
ToppCellIPF-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

PDE1C ANK2 PCLO MUC16 DIP2C

5.91e-051611145f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCellCOVID-19-lung-Mesothelial|COVID-19 / Disease (COVID-19 only), tissue and cell type

MUC16 SEMA6D PRG4 ALOX15 CDON

6.45e-05164114583303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTSL1 MUC16 CHRD PRG4 PCOLCE

7.03e-051671145c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTSL1 MUC16 CHRD PRG4 PCOLCE

7.03e-051671145351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

MUC16 PWWP3B PRG4 ALOX12B ALOX15

7.03e-051671145892a2dc83ab5de5a1016402f8e95d2aabf651326
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIVEP1 SLC24A2 FHOD1 VCAN TLN1

7.64e-0517011459ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 MYO1D MYO1B GRHL1 TMEM108

7.64e-051701145a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PCLO MUC16 PWWP3B PRG4 ALOX15

8.30e-051731145e05cddf5bf63cf419343ff229453327519765be8
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PCLO MUC16 MYO5C PWWP3B ALOX15

8.30e-0517311453d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

PCLO MUC16 PWWP3B PRG4 ALOX15

8.30e-05173114574ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

GPR155 ANK2 ANK3 ITGA2 SEMA6D

8.30e-0517311456fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PCLO MUC16 MYO5C PWWP3B ALOX15

8.30e-0517311453aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 HIVEP1 TMC3 DIP2A CRYBG3

8.53e-05174114599eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK2 VCAN SPARCL1 EPB41L2 CDON

9.24e-051771145bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellfacs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO C6orf132 MYO5C FAN1 PC

9.24e-051771145e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCellfacs-Lung-nan-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO C6orf132 MYO5C FAN1 PC

9.24e-051771145b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

PDE1C ITGA2 APP TMEM108 SPARCL1

9.49e-051781145804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

PDE1C ITGA2 APP TMEM108 SPARCL1

9.49e-051781145ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 HSPH1 MUC16 MYO5C GRHL1

9.75e-0517911456e965e424eebef50f0202cff75f458be395cfca1
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPHB2 ADAMTSL1 VCAN CDON PCOLCE

1.00e-0418011459adebde5f4ca6dcb90e9113622862e14298465ac
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP8AP2 VCAN SPARCL1 EPB41L2 PCOLCE

1.03e-04181114535eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

PDE1C MYO1B C2CD2 SPARCL1 EPB41L1

1.03e-0418111458dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP8AP2 VCAN SPARCL1 EPB41L2 PCOLCE

1.03e-041811145e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ComputationalNeighborhood of RAD54L

ZNF131 CCT4 RUVBL2 XPO6 PRKDC HADH

6.97e-05105726MORF_RAD54L
ComputationalNeighborhood of CDK2

ZNF131 CCT4 RUVBL2 XPO6 PRKDC

1.16e-0472725MORF_CDK2
ComputationalNeighborhood of PRKDC

ZNF131 CCT4 RUVBL2 XPO6 PRKDC HADH HCFC1

2.78e-04191727MORF_PRKDC
ComputationalNeighborhood of CDC10

ZNF131 CCT4 PSME4 XPO6 PRKDC TP53BP1

4.24e-04146726MORF_CDC10
ComputationalNeighborhood of HDAC2

ZNF131 CCT4 RUVBL2 XPO6 PRKDC HADH HCFC1 SON

5.41e-04280728MORF_HDAC2
DrugIsoetharine mesylate salt [7279-75-6]; Down 200; 12uM; PC3; HT_HG-U133A

USP34 PDE1C APP RFX7 XPO6 VCAN NFAT5 EPB41L1 JHY

6.43e-0719611495812_DN
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; MCF7; HT_HG-U133A

ITGA2 APP FHOD1 TLN1 WDFY3 NFAT5 EPB41L2 TP53BP1 SON

7.30e-0719911495283_DN
DrugB0683

ANK2 MYO1D MYO1B ITGA2 MYO5C TMF1 MYO15A

2.06e-061171147CID006398969
Drugformycin triphosphate

MYO1D MYO1B MYO5C MYO15A PC

5.63e-06511145CID000122274
Diseasechronotype measurement

USP34 PDE1C HIVEP1 ANK2 ANK3 FNBP4 SEMA6D NXF5 DIP2C TMEM108 PC JHY

1.35e-0488211212EFO_0008328
Diseasearrhythmogenic right ventricular cardiomyopathy (implicated_via_orthology)

DSC1 DSC2

1.42e-0451122DOID:0050431 (implicated_via_orthology)
Diseaseresponse to stress, systolic blood pressure change measurement

SPG7 MROH2A

1.42e-0451122EFO_0006944, GO_0006950
Diseasedesmocollin-2 measurement

DSC1 DSC2

1.42e-0451122EFO_0021936
DiseaseAdenoid Cystic Carcinoma

VCAN PRKDC MGA SON

5.83e-041001124C0010606
DiseaseDrug habituation

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C0013170
DiseaseDrug abuse

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C0013146
DiseasePrescription Drug Abuse

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C4316881
DiseaseSubstance-Related Disorders

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C0236969
DiseaseDrug Use Disorders

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C0013222
DiseaseDrug Dependence

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C1510472
DiseaseSubstance Dependence

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C0038580
DiseaseSubstance Use Disorders

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

PDE1C MYO5C SEMA6D XPO6

9.84e-041151124C0029231
DiseaseSubstance abuse problem

PDE1C MYO5C SEMA6D XPO6

1.02e-031161124C0740858
Diseaseplasminogen activator inhibitor 1 measurement

RFX7 MUC17 MYOM2

1.15e-03541123EFO_0004792
DiseaseAlzheimer's disease (implicated_via_orthology)

HIVEP1 ANK2 APP

1.34e-03571123DOID:10652 (implicated_via_orthology)
Diseaseresponse to statin, LDL cholesterol change measurement

APOB EPB41L2

1.45e-03151122EFO_0007804, GO_0036273
Diseaselysophosphatidylcholine measurement

MGA DAGLA UVRAG

1.71e-03621123EFO_0010224
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

RFX7 ZNF292

1.87e-03171122DOID:0060307 (is_implicated_in)
Diseasesporadic amyotrophic lateral sclerosis

ADAMTSL1 ANK3 MYOM2 HADH

2.03e-031401124EFO_0001357
Diseasehair colour measurement

SPG7 MROH2A LGR4 SEMA6D HADH PC EPB41L1 EPB41L2

2.43e-036151128EFO_0007822
Diseasenicotine dependence

PDE1C ADAMTSL1 GNAL

3.29e-03781123EFO_0003768
DiseaseR-warfarin measurement

ADAMTSL1 ANK2 SEMA6D XPO6 TMEM108

3.46e-032651125EFO_0803324
DiseaseBehcet Syndrome

APOB STAT4

3.73e-03241122C0004943

Protein segments in the cluster

PeptideGeneStartEntry
SEVPIVKTSSMEISS

CEP170

1461

Q5SW79
LTSSPEDILMVTKDV

ADAL

76

Q6DHV7
SEPIHVTESSVEMTK

VCAN

731

P13611
ISPETMRTTKITEGT

VCAN

1016

P13611
AATKILSEVTRPMSV

CDNF

91

Q49AH0
ETIGATVSTPSVIEM

CRYBG3

1831

Q68DQ2
TVSTPSVIEMEKISP

CRYBG3

1836

Q68DQ2
DALMPSLTETKTTVE

APP

591

P05067
PEITLASTVAETMLS

ADGRG4

586

Q8IZF6
VLLSTTSKEIISSEM

AFTPH

106

Q6ULP2
KEIEASAEVSPTTMT

ACRBP

136

Q8NEB7
LKEVSTVIVVLMSAS

GVINP1

1136

Q7Z2Y8
QPSLSSSTEVVVMVL

FAT4

2131

Q6V0I7
LMDTIVPEKISTSTF

CCDC180

156

Q9P1Z9
VMSTSSLEKIVPIIA

CASP8AP2

1016

Q9UKL3
TVIICKPTMSSAEIV

DSC2

581

Q02487
SLVVTATVKSMVREP

PCOLCE

336

Q15113
SPTSKTERIEETMSV

ANK2

1976

Q01484
TVLSVPAGTTIVKTM

HCFC1

566

P51610
TTIIKTIPMSAIITQ

HCFC1

766

P51610
GIKSPITIITTKVMT

HCFC1

791

P51610
LVETTDGTLVTTIKM

MUC16

3156

Q8WXI7
ETPKATTQMVITTTV

MUC16

5146

Q8WXI7
ESTMLPEISTTRKII

MUC16

7296

Q8WXI7
PILAESSEMTIKTQT

MUC16

7316

Q8WXI7
TTIPASSEITRIEME

MUC16

8981

Q8WXI7
SDEVVTRLSTSPIMT

MUC16

9641

Q8WXI7
SPIMTESAEITITTQ

MUC16

9651

Q8WXI7
VEIPATSEIMTDTEK

MUC16

9791

Q8WXI7
DQSTMSPDIITEVIT

MUC16

9926

Q8WXI7
TATVLTKEADLPMTA

DCAF1

866

Q9Y4B6
QFEPVKTETMTVSSL

EPB41L1

691

Q9H4G0
VITPEMLVVLSTEKT

OR10A3

76

P58181
SMVLTKVSASTVPTD

MAVS

366

Q7Z434
DTSTKPESIVIMHAS

JHY

406

Q6NUN7
SMDVSPVSKEELISI

MAP7D2

646

Q96T17
AVTPMTAISDVETKE

MGA

1611

Q8IWI9
MTEVVPSSALSEVSL

NAA60

1

Q9H7X0
VTETMREKIFTPLTV

MYO15A

1531

Q9UKN7
TIAVNMTKTLPTAVT

GPR155

11

Q7Z3F1
VEVIKTPMTSQKTFE

HADH

181

Q16836
LSHTIEPVMKTSVTT

MCM3AP

1911

O60318
TISTASMVEKVPTEE

HSPH1

491

Q92598
VVAEPEKMESSISSS

CSN1S1

76

P47710
SRMTVINTEKPAVTV

ADAMTSL1

1276

Q8N6G6
PVVKTEMVTISDASQ

EPB41L2

871

O43491
EGVVTKSTPVMIITE

EPHB2

686

P29323
LLSATMPSDVLEVTK

EIF4A1

211

P60842
LSDMASSIIESVVPK

PCLO

2266

Q9Y6V0
TSSVMTKIIEDEKPV

PCLO

2916

Q9Y6V0
SAPVIVDIDSSETMK

NXF5

251

Q9H1B4
EPTFTVLTDMTEKIV

PDE1C

436

Q14123
PTTKDATLETVMATL

ALOX15

566

P16050
LITAISISPEIMKSV

LGR4

771

Q9BXB1
MSEAVVTVTVLGITT

LRIT3

336

Q3SXY7
KVTTGSVPVSMATVI

ITGA2

976

P17301
DVTPMEVTAEKRSST

NFAT5

606

O94916
LVTTAASMPVDIAKT

SLC25A11

231

Q02978
VKDAIVTIVSAMSTI

GNAL

86

P38405
TTLPTTTSQLMAEKD

C6orf132

696

Q5T0Z8
MEVSVATTTKAQIPI

APOB

3421

P04114
ETPIRMSVLSEVTAS

ARMC8

6

Q8IUR7
LSPMQTLKVSVSAVT

HLA-DMB

211

P28068
TLVITNKEETPMSID

HYDIN

4336

Q4G0P3
TVSIATMPTHSIKTE

GRHL1

146

Q9NZI5
LMTPTSVFEKVKTSE

KLHL15

226

Q96M94
KDRTVMPCGTVVTTV

C2CD2

406

Q9Y426
MPCGTVVTTVTAVKT

C2CD2

411

Q9Y426
DRTIMPDGTIVTTVT

C2CD2L

436

O14523
TSKKVTVRPGESVMV

FCGBP

76

Q9Y6R7
AIVMPGTVITTTLEK

FNIP1

561

Q8TF40
MVVPFETNTKAETVT

CDON

516

Q4KMG0
ATTLPTVKMIVEVSR

DIP2C

1066

Q9Y2E4
LRAESEVPIVKTSSM

CEP170P1

166

Q96L14
EVPIVKTSSMEISSI

CEP170P1

171

Q96L14
VVDTLKIVTEETMTT

ANK3

811

Q12955
MRPDVITETVVEVST

ELF2

136

Q15723
TLETFMDTLPDVKTT

ALOX12B

611

O75342
TALLSAAKVMVSPTE

DAGLA

671

Q9Y4D2
PTMCTTTVTVKIIDS

DSC1

451

Q08554
KDTLMISRTPEVTCV

IGHG1

131

P01857
GTTLPTVKMIVEVSK

DIP2A

1081

Q14689
EIMDLLVQSVTKSSP

FHOD1

1106

Q9Y613
SEMITTVSEIESKAP

CEP295

411

Q9C0D2
TAAMITETIIETDKP

ARCN1

196

P48444
MKVASSEAITLLTTP

MUC17

226

Q685J3
PETISAQMELTVTVT

MUC17

4181

Q685J3
SVIIMEKATTEPSVV

MROH2A

66

A6NES4
MVDLTSVTLEDVTPK

FAN1

86

Q9Y2M0
MATVTATTKVPEIRD

RUVBL2

1

Q9Y230
VTTVPSMGETERKIT

UVRAG

531

Q9P2Y5
EVSVVVSLVTMIAPS

TMC3

361

Q7Z5M5
ILETTMTPTGIDTAK

SYNRG

306

Q9UMZ2
TVEEATTIVKPQEIM

FNBP4

361

Q8N3X1
KIELPNSTSTDVEMT

SLC24A2

411

Q9UI40
ELTMSEGAVVTITTP

PKNOX1

361

P55347
APTMVDTIPSEVETK

PWWP3B

171

Q5H9M0
KSMIVKVSETASPQV

PSG6

406

Q00889
EVFPVSKTLVLMEIT

RIF1

541

Q5UIP0
VMTITKLTQKPSEFT

PKDREJ

756

Q9NTG1
VMKVIDPATATSVDL

CCT4

191

P50991
EHTEAVMKVSITPRT

SPG7

586

Q9UQ90
TITTTEIMNKPEETA

PRG4

991

Q92954
EVTKTAVTTVPSMGI

TMEM263

66

Q8WUH6
TSSEVVAMTLETKPQ

CHRD

446

Q9H2X0
DMKVPTVSLKVSESV

TMF1

186

P82094
VSESVIDVKTTMESI

TMF1

196

P82094
TVPLTRVKCLVSMTT

WDFY3

1016

Q8IZQ1
VTVQEMVTKSNTSPE

TLN1

1866

Q9Y490
TIDLETSSLPVVMIS

STAT4

441

Q14765
TEEKTVSEALLMEPT

SPARCL1

311

Q14515
VSMGAVSKETPVVTI

MTHFSD

166

Q2M296
STADITVIQPVSEMI

ZNF292

1876

O60281
SSLNVVKMTTISLTP

RFX7

371

Q2KHR2
MEVETSVISIDSPQK

TP53BP1

716

Q12888
VTNLVPSMVSLEETK

PSME4

836

Q14997
PEETLSLMTKEISSV

PRKDC

3476

P78527
KSTTPCMVRTSQVVE

ZHX2

6

Q9Y6X8
PEQRTSSMVSEVKTI

RELT

356

Q969Z4
SVETRVQTEPVTSMT

ZNF131

456

P52739
DMKTETREVLTPTST

USP34

3371

Q70CQ2
VTTPLGLIMLKTTSE

XPO6

141

Q96QU8
TTMDAITPLISTKVQ

XPO6

656

Q96QU8
SVTTMASIPEITPKV

SEMA6D

596

Q8NFY4
ETVVTSPMEGTVRKV

PC

1146

P11498
VTSATLPTKLIDSMS

HIVEP1

1596

P15822
AVTVAMELTEQPVTT

SON

496

P18583
MIVSEPSVSVQESTV

SON

1431

P18583
KEETVATLTMTDRVP

TMEM108

401

Q6UXF1
IPTEKPTISMEETII

ZAN

691

Q9Y493
KSEVPLVDVTKVSMS

MYO1B

1026

O43795
VVSIIAELLSTKTDM

MYO1D

296

O94832
RKIVTSSETVVKPMT

MYO5C

376

Q9NQX4
EGETVTLKCTMLVTP

MYOM2

291

P54296