Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionallyl-alcohol dehydrogenase activity

AKR1B10 AKR1B15 AKR1B1

5.01e-0741013GO:0047655
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1B10 AKR1B15 AKR1B1

4.39e-05141013GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1B10 AKR1B15 AKR1B1

4.39e-05141013GO:0001758
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NADP+) activity

AKR1B10 AKR1B15 AKR1B1

5.47e-05151013GO:0052650
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1B10 AKR1B15

1.51e-0441012GO:0047718
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1B10 AKR1B15 AKR1B1

3.36e-04271013GO:0008106
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1B10 AKR1B15

3.75e-0461012GO:0045550
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1B10 AKR1B15 AKR1B1

5.60e-04321013GO:0004033
GeneOntologyMolecularFunctionNADP+ binding

AKR1B10 AKR1B15

8.91e-0491012GO:0070401
DomainALDOKETO_REDUCTASE_1

AKR1B10 AKR1B15 AKR1B1

1.59e-0510973PS00798
DomainALDOKETO_REDUCTASE_2

AKR1B10 AKR1B15 AKR1B1

1.59e-0510973PS00062
DomainALDOKETO_REDUCTASE_3

AKR1B10 AKR1B15 AKR1B1

1.59e-0510973PS00063
DomainAldo/ket_reductase_CS

AKR1B10 AKR1B15 AKR1B1

1.59e-0510973IPR018170
DomainAldo/keto_reductase

AKR1B10 AKR1B15 AKR1B1

1.59e-0510973IPR020471
DomainPLC-gamma

PLCG1 PLCG2

2.67e-052972IPR016279
Domain-

AKR1B10 AKR1B15 AKR1B1

7.24e-05169733.20.20.100
DomainNADP_OxRdtase_dom

AKR1B10 AKR1B15 AKR1B1

8.76e-0517973IPR023210
DomainAldo_ket_red

AKR1B10 AKR1B15 AKR1B1

8.76e-0517973PF00248
DomainAldo/ket_red/Kv-b

AKR1B10 AKR1B15 AKR1B1

8.76e-0517973IPR001395
DomainPH

ARHGAP10 TEC ARAP3 DGKK OSBPL8 PLCG1 PLCG2

1.92e-04229977PF00169
DomainSMC

SMC1A SMC1B

2.64e-045972IPR024704
DomainSMC_hinge

SMC1A SMC1B

3.95e-046972SM00968
DomainSMC_hinge

SMC1A SMC1B

3.95e-046972PF06470
DomainSMC_hinge

SMC1A SMC1B

3.95e-046972IPR010935
DomainPH

ARHGAP10 TEC ARAP3 DGKK OSBPL8 PLCG1 PLCG2

6.16e-04278977SM00233
DomainPH_DOMAIN

ARHGAP10 TEC ARAP3 DGKK OSBPL8 PLCG1 PLCG2

6.29e-04279977PS50003
DomainPH_domain

ARHGAP10 TEC ARAP3 DGKK OSBPL8 PLCG1 PLCG2

6.43e-04280977IPR001849
DomainS15_NS1_RNA-bd

MARS1 RPS13

7.32e-048972IPR009068
DomainRecF/RecN/SMC_N

SMC1A SMC1B

7.32e-048972IPR003395
DomainSMC_N

SMC1A SMC1B

7.32e-048972PF02463
DomainSH2

TEC PTPN6 PLCG1 PLCG2

1.90e-03101974PF00017
DomainSH2

TEC PTPN6 PLCG1 PLCG2

2.59e-03110974SM00252
DomainSH2

TEC PTPN6 PLCG1 PLCG2

2.68e-03111974PS50001
DomainEF-hand_like

PLCG1 PLCG2

2.68e-0315972PF09279
DomainPI-PLC-Y

PLCG1 PLCG2

2.68e-0315972PF00387
DomainPLCYc

PLCG1 PLCG2

2.68e-0315972SM00149
DomainPLipase_C_Pinositol-sp_Y

PLCG1 PLCG2

2.68e-0315972IPR001711
DomainPIPLC_Y_DOMAIN

PLCG1 PLCG2

2.68e-0315972PS50008
DomainPI-PLC_fam

PLCG1 PLCG2

2.68e-0315972IPR001192
DomainPLC_EF-hand-like

PLCG1 PLCG2

2.68e-0315972IPR015359
DomainSH2

TEC PTPN6 PLCG1 PLCG2

2.77e-03112974IPR000980
Domain-

TEC PTPN6 PLCG1 PLCG2

2.77e-031129743.30.505.10
DomainMMR_HSR1

DRG2 NOA1

3.45e-0317972PF01926
DomainPI-PLC-X

PLCG1 PLCG2

3.87e-0318972PF00388
DomainPLCXc

PLCG1 PLCG2

3.87e-0318972SM00148
DomainRhoGAP

STARD13 ARHGAP10 ARAP3

4.11e-0362973SM00324
Domain-

ARHGAP10 TEC ARAP3 DGKK OSBPL8 PLCG1 PLCG2

4.27e-033919772.30.29.30
DomainRhoGAP

STARD13 ARHGAP10 ARAP3

4.30e-0363973PF00620
DomainGTP_binding_domain

DRG2 NOA1

4.31e-0319972IPR006073
DomainPIPLC_X_DOMAIN

PLCG1 PLCG2

4.31e-0319972PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCG1 PLCG2

4.31e-0319972IPR000909
DomainRhoGAP_dom

STARD13 ARHGAP10 ARAP3

4.50e-0364973IPR000198
DomainRHOGAP

STARD13 ARHGAP10 ARAP3

4.50e-0364973PS50238
Domain-

STARD13 ARHGAP10 ARAP3

4.50e-03649731.10.555.10
PathwayPID_EPO_PATHWAY

TEC PTPN6 PLCG1 PLCG2

2.69e-0533754M233
Pubmed

Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.

AKR1B10 AKR1B15 AKR1B1

2.60e-083104317381426
Pubmed

Dephosphorylation of the adaptor LAT and phospholipase C-γ by SHP-1 inhibits natural killer cell cytotoxicity.

PTPN6 PLCG1 PLCG2

1.04e-074104327221712
Pubmed

Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes.

AKR1B10 AKR1B15 AKR1B1

2.59e-075104310092857
Pubmed

Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker.

TEC PLCG1 PLCG2

2.59e-075104315184383
Pubmed

Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.

FRMD8 F8 FRMD8P1

5.16e-076104329776906
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

STARD13 COMT MARS1 SMC1A RPS13 PHB2 EEF1B2 CS ARAP3 RBM19 PDCD11 PLCG1 PLCG2 PARD3 DHX29 UTRN PCK2

5.43e-0713531041729467282
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

TES DRG2 DMAC2 PHB2 MAP3K4 EEF1B2 EHMT2 PDCD11 SMARCD2 PLCG1 DHX29 PCK2

1.36e-067041041229955894
Pubmed

Fine specificity and molecular competition in SLAM family receptor signalling.

PTPN6 PLCG1 PLCG2

3.07e-0610104324642916
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

CYLD ARHGAP10 SLC26A2 NOA1 GRIK1 METTL6 SEMA3D NEK5 MANSC4 DHX29 HYDIN

6.88e-066861041129987050
Pubmed

Role of AKR1B10 and AKR1B8 in the pathogenesis of non-alcoholic steatohepatitis (NASH) in mouse.

AKR1B10 AKR1B15

8.86e-062104234954342
Pubmed

SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage.

SMC1A SMC1B

8.86e-062104229337080
Pubmed

Aldose reductase (AC)n gene polymorphism and susceptibility to diabetic retinopathy in Type 2 diabetes in Caucasians.

AKR1B10 AKR1B1

8.86e-062104215745835
Pubmed

Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway.

AKR1B10 AKR1B15

8.86e-062104225120755
Pubmed

Phospholipase C gamma 2 is essential for specific functions of Fc epsilon R and Fc gamma R.

PLCG1 PLCG2

8.86e-062104212471105
Pubmed

Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10.

AKR1B10 AKR1B15

8.86e-062104221087085
Pubmed

Tissue-specific expression of two aldose reductase-like genes in mice: abundant expression of mouse vas deferens protein and fibroblast growth factor-regulated protein in the adrenal gland.

AKR1B10 AKR1B15

8.86e-06210428526877
Pubmed

Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: role of Trp112 (Trp111).

AKR1B10 AKR1B1

8.86e-062104224100137
Pubmed

Molecular species of phospholipids in a murine stem-cell line responsive to erythropoietin.

PLCG1 PLCG2

8.86e-06210428615781
Pubmed

AKR1B8 deficiency drives severe DSS-induced acute colitis through invasion of luminal bacteria and activation of innate immunity.

AKR1B10 AKR1B15

8.86e-062104236518763
Pubmed

Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer.

AKR1B10 AKR1B1

8.86e-062104228929377
Pubmed

1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor.

AKR1B10 AKR1B15

8.86e-06210427578036
Pubmed

Characterization of the promoter of the gene for a mouse vas deferens protein related to the aldo-keto reductase superfamily: effect of steroid hormones and phorbol esters.

AKR1B10 AKR1B15

8.86e-06210428541228
Pubmed

Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway.

AKR1B10 AKR1B1

8.86e-062104232628753
Pubmed

Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice.

AKR1B10 AKR1B15

8.86e-062104233644071
Pubmed

Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism.

AKR1B10 AKR1B1

8.86e-062104212732097
Pubmed

Aldo Keto Reductases AKR1B1 and AKR1B10 in Cancer: Molecular Mechanisms and Signaling Networks.

AKR1B10 AKR1B1

8.86e-062104233945128
Pubmed

Restoration of responsiveness of phospholipase Cγ2-deficient platelets by enforced expression of phospholipase Cγ1.

PLCG1 PLCG2

8.86e-062104225793864
Pubmed

Evaluation of compound selectivity of aldo-keto reductases using differential scanning fluorimetry.

AKR1B10 AKR1B1

8.86e-062104228003428
Pubmed

Decreased levels of AKR1B1 and AKR1B10 in cancerous endometrium compared to adjacent non-cancerous tissue.

AKR1B10 AKR1B1

8.86e-062104223146748
Pubmed

Identification and characterization of a novel human aldose reductase-like gene.

AKR1B10 AKR1B1

8.86e-06210429565553
Pubmed

Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.

AKR1B10 AKR1B15

8.86e-062104225538260
Pubmed

Functional expression of novel human and murine AKR1B genes.

AKR1B10 AKR1B15

8.86e-062104221276782
Pubmed

Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis.

AKR1B10 AKR1B15

8.86e-062104231911858
Pubmed

Human aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds.

AKR1B10 AKR1B1

8.86e-062104221329684
Pubmed

The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors.

PLCG1 PLCG2

8.86e-062104215972651
Pubmed

Aldo-keto reductases-mediated cytotoxicity of 2-deoxyglucose: A novel anticancer mechanism.

AKR1B10 AKR1B1

8.86e-062104229617059
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

STARD13 COMT LONP2 ARHGAP10 SMC1A RPS13 PHB2 USP8 CS NEK5 CEP44 TRAPPC10 PARD3 CTSV PCK2

9.15e-0613211041527173435
Pubmed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

CS AKR1B10 AKR1B15 AKR1B1 PCK2

2.46e-05114104528245920
Pubmed

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

TEC PLCG1

2.65e-053104215214048
Pubmed

Novel meiosis-specific isoform of mammalian SMC1.

SMC1A SMC1B

2.65e-053104211564881
Pubmed

FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.

FRMD8 FRMD8P1

2.65e-053104237527040
Pubmed

Phospholipase Cγ2 plays a role in TCR signal transduction and T cell selection.

PLCG1 PLCG2

2.65e-053104222837484
Pubmed

Differential and nonredundant roles of phospholipase Cgamma2 and phospholipase Cgamma1 in the terminal maturation of NK cells.

PLCG1 PLCG2

2.65e-053104217015722
Pubmed

Real time fluorescence imaging of PLC gamma translocation and its interaction with the epidermal growth factor receptor.

PLCG1 PLCG2

2.65e-053104211331309
Pubmed

A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase.

AKR1B10 AKR1B15

2.65e-05310427510692
Pubmed

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

PLCG1 PLCG2

2.65e-053104229133930
Pubmed

Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.

PLCG1 PLCG2

2.65e-053104228786489
Pubmed

SH3BP2 mutations potentiate osteoclastogenesis via PLCγ.

PLCG1 PLCG2

2.65e-053104220872577
Pubmed

Potential role of Gab1 and phospholipase C-gamma in osmotic shock-induced glucose uptake in 3T3-L1 adipocytes.

PLCG1 PLCG2

2.65e-053104211507676
Pubmed

Tau complexes with phospholipase C-gamma in situ.

PLCG1 PLCG2

2.65e-05310429592050
Pubmed

A novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinase.

PLCG1 PLCG2

2.65e-053104210770799
Pubmed

The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.

FRMD8 FRMD8P1

2.65e-053104236720499
Pubmed

Phospholipase C gamma-2 (Plcg2) and phospholipase C gamma-1 (Plcg1) map to distinct regions in the human and mouse genomes.

PLCG1 PLCG2

5.29e-05410427774933
Pubmed

An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion.

PLCG1 PLCG2

5.29e-054104215372077
Pubmed

Ca(2+)-dependent reduction of glutamate aspartate transporter GLAST expression in astrocytes by P2X(7) receptor-mediated phosphoinositide 3-kinase signaling.

PLCG1 PLCG2

5.29e-054104220070863
Pubmed

ESCRT machinery potentiates HIV-1 utilization of the PI(4,5)P(2)-PLC-IP3R-Ca(2+) signaling cascade.

PLCG1 PLCG2

5.29e-054104221875593
Pubmed

Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family.

CD84 PTPN6

5.29e-054104211414741
Pubmed

Interactions of FLT-1 and KDR with phospholipase C gamma: identification of the phosphotyrosine binding sites.

PLCG1 PLCG2

5.29e-05410429398617
Pubmed

Dynamic regulation of Tec kinase localization in membrane-proximal vesicles of a T cell clone revealed by total internal reflection fluorescence and confocal microscopy.

TEC PLCG1

5.29e-054104215817477
Pubmed

CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation.

PTPN6 PLCG1

5.29e-05410428627166
Pubmed

Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase.

PLCG1 PLCG2

5.29e-054104218378693
Pubmed

Interferon-induced guanylate-binding proteins: mapping of the murine Gbp-1 locus to chromosome 3.

GBP2 AKR1B1

5.29e-05410423927587
Pubmed

Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis.

SMC1A SMC1B

5.29e-054104227792785
Pubmed

Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice.

PLCG1 PLCG2

5.29e-054104211744703
Pubmed

Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.

PLCG1 PLCG2

5.29e-054104217023658
Pubmed

Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.

AKR1B10 AKR1B15

5.29e-054104221179467
Pubmed

VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.

TES RPS13 PHB2 EEF1B2 CS AKR1B10 AKR1B1

6.16e-05329104735562734
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

DRG2 COMT MARS1 NOA1 DMAC2 PHB2 OTC CS TAMM41 AKR1B10 DHX29 PCK2

7.07e-0510471041218614015
Pubmed

Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.

TEC PTPN6 PLCG1 PLCG2

8.63e-0577104422973453
Pubmed

LAB: a new membrane-associated adaptor molecule in B cell activation.

PLCG1 PLCG2

8.80e-055104212514734
Pubmed

FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.

FRMD8 FRMD8P1

8.80e-055104229897336
Pubmed

iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.

FRMD8 FRMD8P1

8.80e-055104229897333
Pubmed

Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity.

PLCG1 PLCG2

8.80e-05510429819383
Pubmed

Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31.

PTPN6 PLCG1

8.80e-055104210350061
Pubmed

Identification and molecular characterization of the mammalian α-kleisin RAD21L.

SMC1A SMC1B

8.80e-055104221527826
Pubmed

Molecular evolutionary analysis of the widespread piggyBac transposon family and related "domesticated" sequences.

PGBD4 PGBD3

8.80e-055104212955498
Pubmed

Sprouty proteins inhibit receptor-mediated activation of phosphatidylinositol-specific phospholipase C.

PLCG1 PLCG2

8.80e-055104220719962
Pubmed

DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population.

DMAC2 PARD3

8.80e-055104221682944
Pubmed

Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators.

SMC1A SMC1B

8.80e-055104218219272
Pubmed

Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice.

PLCG1 PLCG2

8.80e-055104219056831
Pubmed

Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis.

SMC1A SMC1B

8.80e-055104212759374
Pubmed

Butylated hydroxyanisole induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice.

AKR1B10 AKR1B15

8.80e-055104226291391
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 MARS1 RPS13 PHB2 EEF1B2 CS RNPEP AKR1B10 OSBPL8 TRAPPC10 CROCC AKR1B1 DHX29 UTRN

9.34e-0514311041437142655
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

DRG2 COMT MARS1 NOA1 DMAC2 PHB2 CS TAMM41 AKR1B15 DHX29 PCK2

1.05e-049261041120877624
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

EHMT2 OSBPL8 PARD3 UTRN GOLGA2

1.20e-04159104530581152
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CYLD TES DCDC1 ARHGAP10 KAT6A PEX1 NSRP1 RESF1 TAF9B EHMT2 SMARCD2 PARD3

1.29e-0411161041231753913
Pubmed

Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex.

PLCG1 PLCG2

1.32e-04610428739298
Pubmed

Sprouty2 regulates PI(4,5)P2/Ca2+ signaling and HIV-1 Gag release.

PLCG1 PLCG2

1.32e-046104221762810
Pubmed

Cep44 functions in centrosome cohesion by stabilizing rootletin.

CEP44 CROCC

1.32e-046104231974111
Pubmed

Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1.

PLCG1 PLCG2

1.32e-046104214978237
Pubmed

Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways.

TEC PLCG1

1.32e-04610428892607
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PITPNM2 ARHGAP10 MARS1 KAT6A DMAC2 ANKMY1 GRIK1 NSRP1 GALNT11 PLCG1 PARD3 CROCC UTRN DOP1A

1.42e-0414891041428611215
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

DRG2 MARS1 SMC1A RPS13 PHB2 EEF1B2 CS TAF9B TAMM41 OSBPL8 PDCD11 SMARCD2 PCK2

1.56e-0413181041330463901
Pubmed

Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.

TES CELSR3

1.84e-047104217937400
Pubmed

Comparison of the physical and recombination maps of the mouse X chromosome.

F8 OTC

1.84e-04710422571569
Pubmed

Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins.

TES SPOCK3

1.84e-047104212810672
Pubmed

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.

CFAP52 DNAH17

1.84e-047104233139725
Pubmed

TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk.

PLCG1 PLCG2

1.84e-047104227609517
Pubmed

Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cgamma.

PLCG1 PLCG2

1.84e-047104215953601
Pubmed

Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo.

PLCG1 PLCG2

1.84e-047104217634444
GeneFamilyAldo-keto reductases

AKR1B10 AKR1B15 AKR1B1

2.05e-0515663399
GeneFamilyStructural maintenance of chromosomes proteins|Cohesin complex

SMC1A SMC1B

2.72e-047662761
GeneFamilyCohesin complex

SMC1A SMC1B

3.62e-0486621060
GeneFamilyPhospholipases

PLA1A PLCG1 PLCG2

4.82e-0442663467
GeneFamilySH2 domain containing

TEC PTPN6 PLCG1 PLCG2

5.07e-04101664741
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCG1 PLCG2

2.16e-0319662832
ToppCellSubstantia_nigra-Macroglia-CSF_related|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CFAP52 NEK5 CIBAR2 HYDIN LRRC36 SMC1B

8.12e-07136104647663c5d81c766a333207a44fc5b58b07309ee76
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CFAP52 NEK5 CIBAR2 HYDIN LRRC36 SMC1B

8.12e-0713610466d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CFAP52 NEK5 CIBAR2 HYDIN LRRC36 SMC1B

8.12e-071361046fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CFAP52 NEK5 CIBAR2 HYDIN LRRC36 SMC1B

8.12e-0713610463f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CFAP52 NEK5 CIBAR2 HYDIN LRRC36 SMC1B

8.12e-07136104667d736096d6b6ddb4722809557f5e987063b8d23
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 CIBAR2 CROCC HYDIN LRRC36

3.29e-061731046a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 CIBAR2 CROCC HYDIN LRRC36

3.29e-061731046e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 CIBAR2 CROCC HYDIN LRRC36

3.75e-061771046e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 CFAP52 NEK5 CIBAR2 HYDIN LRRC36

3.75e-061771046ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 CFAP52 NEK5 CIBAR2 HYDIN LRRC36

3.75e-061771046bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 CIBAR2 CROCC HYDIN LRRC36

3.88e-061781046b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 CIBAR2 CROCC HYDIN LRRC36

3.88e-061781046579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYLD GBP2 ZNF831 CD84 RESF1 PNRC1

4.27e-061811046a6c8b33a392de3df2f179317e329e45d3d8c6f52
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 CFAP52 NEK5 CIBAR2 HYDIN LRRC36

4.41e-061821046587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 CFAP52 NEK5 CIBAR2 HYDIN LRRC36

4.41e-061821046adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCellCiliated_cells-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

4.84e-061851046d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DCDC1 CFAP52 NEK5 CIBAR2 CROCC HYDIN

4.99e-06186104685787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

DCDC1 CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

5.31e-06188104626326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCellASK454-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

ANKMY1 USP8 CFAP52 GALNT11 CROCC HYDIN

5.64e-0619010465cea6480f08253d7adf484e511d3fdfa96641268
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

DCDC1 CFAP52 NEK5 CIBAR2 PARD3 HYDIN

6.54e-06195104621dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 CFAP52 NEK5 CIBAR2 CROCC HYDIN

6.54e-06195104679dc031258579ea328181dda33710dd897f1064a
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

DCDC1 CFAP52 NEK5 CIBAR2 PARD3 HYDIN

6.74e-06196104687d9881cfec461a5d89b688a83749b618c519485
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

7.56e-062001046cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

7.56e-06200104679e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ANKMY1 CFAP52 PLA1A CIBAR2 CTSV HYDIN

7.56e-062001046da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

7.56e-062001046873def69bf55ccbfc944bc10c5afc06be019c312
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ANKMY1 CFAP52 PLA1A CIBAR2 CTSV HYDIN

7.56e-06200104672c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellIIH-CD8-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

ZNF831 F8 NEK5 GALNT11 DHX29

2.39e-0514610457fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCellHippocampus-Macroglia-CSF_related|Hippocampus / BrainAtlas - Mouse McCarroll V32

CFAP52 NEK5 CIBAR2 HYDIN LRRC36

2.89e-051521045c2b6cc41546cbd46b9ea5d28a7c66f6330a27df2
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

4.16e-0516410450e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDNF COL6A6 CIBAR2 HYDIN

4.30e-058310441ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDNF COL6A6 CIBAR2 HYDIN

4.30e-0583104475b27d91a4473286f4b40027e96ac5246f5abe5b
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF831 F8 SEMA3D ARAP3 UTRN

4.54e-051671045b93103a868fba63a8910bffb690a6242b9252833
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF831 F8 SEMA3D ARAP3 UTRN

4.54e-051671045fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF831 F8 SEMA3D ARAP3 UTRN

4.54e-051671045f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF831 F8 SEMA3D ARAP3 UTRN

4.54e-05167104526cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCellCiliated_cells-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

4.54e-051671045edb722ee9b6ccd00fb038f702be8664020932659
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIRPD PTPN6 CS CELSR3 AKR1B1

4.94e-05170104579420950d5e4b5da9f52d2a8a8ce096ae44a5edf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYLD TES ZNF831 RESF1 UTRN

5.08e-051711045e1fe07652c10c37191d1471ddaea500f74269e0c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDNF HPSE2 GRIK1 SPOCK3 PARD3

5.36e-051731045af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

5.36e-051731045c3762655caa79ac4879876f470d32578a3c93b01
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP10 DNAH17 PARD3 UTRN HYDIN

5.82e-051761045327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNBD1 GRIK1 SPOCK3 DGKK UTRN

5.82e-051761045d09e28606e2a6ed1f660898316765ca215085c18
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

5.98e-051771045c38138fb5ad9766c2d240811210c854338cd612e
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 CFAP52 NEK5 HYDIN LRRC36

6.14e-0517810456178706db4a855d72abc156537604d575624df56
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 CFAP52 NEK5 HYDIN LRRC36

6.14e-051781045f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

F8 SEMA3D KCNN3 PLCG2 UTRN

6.14e-051781045ad3de3e03a401dac64431a541899445262246347
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NDNF GRIK1 F8 SPOCK3 KCNN3

6.30e-051791045ec1d7017da325647b629de703135a404bbdc627d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDNF HPSE2 GRIK1 SPOCK3 PARD3

6.30e-05179104597ba67a856680f24846244c0b92c886cc0e79537
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDNF HPSE2 GRIK1 SPOCK3 PARD3

6.47e-051801045b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDNF HPSE2 GRIK1 SPOCK3 PARD3

6.82e-0518210457dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

6.82e-0518210457ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

6.82e-051821045fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

6.82e-051821045e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.00e-051831045b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

7.00e-05183104558847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 ARHGAP10 RGS6 KCNN3 HYDIN

7.00e-0518310451645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.00e-051831045cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 KAT6A ARAP3 SPOCK3 LRRC36

7.00e-051831045e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP52 NEK5 CIBAR2 HYDIN LRRC36

7.18e-051841045264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 ARHGAP10 RGS6 KCNN3 HYDIN

7.18e-05184104534e316ad8e7b8667cd8ad61397281802a252744f
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP52 NEK5 CIBAR2 HYDIN LRRC36

7.18e-051841045d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP52 NEK5 CIBAR2 HYDIN LRRC36

7.18e-05184104522010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.18e-0518410455daff849625f2f41d56615569c0ed59cd733b34c
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.37e-0518510454fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.37e-051851045f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITPNM2 ZNF354A F8 SEMA3D TAF9B

7.37e-051851045bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.37e-05185104518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.56e-051861045f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.56e-05186104576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STARD13 PITPNM2 KAT6A SPOCK3 LRRC36

7.75e-051871045ea9d34bcd3bd1f36745846309ede349773de501a
ToppCelltumor_Lung-Epithelial_cells-tS3|Epithelial_cells / Location, Cell class and cell subclass

CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

7.75e-0518710453cea677279e71fdb9879530dea10a5e6393beacd
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.75e-0518710452b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.75e-051871045f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

7.75e-0518710456fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

7.75e-05187104588f785932e67c613db0dda84496de351359ed962
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP52 NEK5 KCNN3 CIBAR2 HYDIN

7.75e-0518710458896a00b30d11b90ca42726d4e122174a30b161b
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.75e-051871045bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.95e-05188104561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.95e-05188104534b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.95e-0518810452b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

7.95e-0518810459a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.15e-051891045a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.15e-05189104568a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.15e-051891045dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.15e-051891045c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.15e-051891045b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.15e-05189104527329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.15e-0518910453e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCiliated|World / shred by cell class for parenchyma

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.15e-051891045711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.35e-0519010459ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.35e-051901045169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.35e-0519010450cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.35e-051901045833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.35e-0519010457031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP52 NEK5 CIBAR2 HYDIN LRRC36

8.35e-051901045088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.35e-051901045a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP52 NEK5 CIBAR2 HYDIN LRRC36

8.35e-05190104535248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DCDC1 CFAP52 NEK5 CIBAR2 HYDIN

8.35e-051901045426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellSevere-Lymphoid-NK-Treg|Severe / Condition, Lineage, Cell class and cell subclass

ZNF354A POT1 PEX1 TAMM41 TONSL

8.35e-051901045e67803bf55a3f8e47a69ff1829c9100f870d7527
DrugMesalamine [89-57-6]; Down 200; 26.2uM; HL60; HT_HG-U133A

ZNF354A MARS1 SMC1A KAT6A PEX1 TEC CAPN7 PARD3 DHX29 UTRN

1.56e-08192102106162_DN
Druglindane

MARS1 CS RNPEP AKR1B10 TONSL PLCG1 PLCG2

6.09e-061541027CID000000727
DrugGlyceraldehyde

AKR1B10 AKR1B15 AKR1B1

1.02e-05101023ctd:D005985
Drug4-oxoretinaldehyde

AKR1B10 AKR1B1

1.99e-0521022ctd:C099660
Drugpropioin

AKR1B10 AKR1B1

1.99e-0521022ctd:C523189
Drugdehydroretinal

AKR1B10 AKR1B1

1.99e-0521022ctd:C017184
DrugPentanones

AKR1B10 AKR1B1

1.99e-0521022ctd:D010422
Drug4-hydroxyretinal

AKR1B10 AKR1B1

1.99e-0521022ctd:C057180
Drug6-demethoxycapillarisin

AKR1B1 PCK2

1.99e-0521022CID005316511
Drug15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

CYLD ARHGAP10 MARS1 DMAC2 PTPN6 PLCG1 CROCC

3.11e-0519810277526_DN
DrugIsopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; PC3; HT_HG-U133A

KAT6A PEX1 ANKMY1 RESF1 PNRC1 PARD3 GOLGA2

3.21e-0519910275879_DN
Drugcitric acid

SLC26A2 MARS1 TEC F8 OTC CS TONSL AKR1B1 PCK2

3.29e-053571029CID000000311
Drug3-aminophenylboronic acid

TES MARS1 GRIK1 RNPEP PLCG2

4.04e-05851025CID000092269
Diseasealdose reductase measurement

AKR1B10 AKR1B1

6.79e-0541002EFO_0801364
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

6.79e-0541002EFO_0020830
Diseasetestosterone measurement

STARD13 DRG2 DCDC1 ARHGAP10 MARS1 SEMA3D RGS6 DGKK AKR1B15 PLCG1 AKR1B1 UTRN LRRC36

3.73e-04127510013EFO_0004908
Diseasesymmetrical dimethylarginine measurement

AKR1B10 AKR1B15

4.03e-0491002EFO_0006523
Diseasewhite matter growth measurement

AKR1B10 AKR1B1

4.03e-0491002EFO_0009335
Diseasejuvenile rheumatoid arthritis (is_implicated_in)

SLC26A2 CIITA

8.66e-04131002DOID:676 (is_implicated_in)
Diseaseulcerative colitis

ZNF831 TRAM1L1 CELSR3 CIITA EHMT2 PLCG2

9.98e-043351006EFO_0000729
DiseaseEndometrial Neoplasms

MAP3K4 AKR1B10 AKR1B1

1.02e-03581003C0014170
Diseaseceramide measurement

STARD13 ANKMY1 TEC PLCG2 TEC

1.25e-032351005EFO_0010222
DiseaseMyeloid Leukemia

SMC1A SMARCD2

1.68e-03181002C0023470
DiseaseLeukemia, Monocytic, Chronic

SMC1A SMARCD2

1.68e-03181002C0023466
Diseasecystathionine measurement

TEC TEC

1.87e-03191002EFO_0010474
DiseaseEndometrial Carcinoma

MAP3K4 AKR1B10 AKR1B1

1.90e-03721003C0476089

Protein segments in the cluster

PeptideGeneStartEntry
KLKKSYCQRQGVPVN

SUMO1P1

46

G2XKQ0
TKVVNPLKLYGAQIK

CIBAR2

91

Q6ZTR7
LPQKNQRLEKYKDVI

ARAP3

1006

Q8WWN8
KKKPFVYTQGQAVLN

RNPEP

161

Q9H4A4
RKKGYVTPVKNQKQC

CTSV

121

O60911
QKVLARYLKRLQPGT

CIITA

786

P33076
RKKHIYIPKNGQINF

GOT1L1

366

Q8NHS2
LNYKDKKLNIGPAIR

BOLL

96

Q8N9W6
KAPSRYNIKIKIRQL

GRIK1

191

P39086
YNIKIKIRQLPSGNK

GRIK1

196

P39086
NYKPILTKKQFIQCG

CEP44

86

Q9C0F1
LNKPGLKYKPVTNQV

AKR1B10

171

O60218
NAKYQVVPKKLTIGK

DOP1A

51

Q5JWR5
PRQLYLSVKQGELQK

EHMT2

651

Q96KQ7
PEGNQKKKRTILQFL

DMAC2

31

Q9NW81
LQSTPKYQKLLKERQ

DHX29

556

Q7Z478
IKKQIRQREKYGPNP

ARMCX5

281

Q6P1M9
LNKPGLKYKPAVNQI

AKR1B1

171

P15121
YNQLKQKGVKVPPLQ

CCDC27

626

Q2M243
YRKPEQAQKALKQLQ

RBM19

781

Q9Y4C8
RQYGLILPKKTQQLH

NSRP1

6

Q9H0G5
NGKKTKRPRVIVDYN

PGBD4

411

Q96DM1
RRLKNPQKVKKSVYG

RGS6

221

P49758
QIGLLNKDLKPQTYR

INTS6L

496

Q5JSJ4
VALQTKGALQKKPLY

KCNK9

206

Q9NPC2
LNPIIYGVKTKQIKD

OR52Z1P

271

P0C646
LNGKRGLIPQNYVKL

ARHGAP10

771

A1A4S6
KRIAVKPSNLYKQPN

DCDC1

1651

M0R2J8
IQRPGLIKIRYKNAA

DGKK

1016

Q5KSL6
YLAVRQLKNNLKGPI

LONP2

356

Q86WA8
VQLKPKHQPYKLGRQ

FRMD8

86

Q9BZ67
VQLKPKNQPYKLGRQ

FRMD8P1

86

Q9BZ68
YKPIKKIQLQGGITS

CFAP52

281

Q8N1V2
LLEQQGLIRKLPKYN

PCK2

76

Q16822
INRQKSKYNLPLTKI

PNRC1

211

Q12796
PKANKRKNQNIGYKL

KCNN3

256

Q9UGI6
LLQQLNKEPKGYSGK

LRRC36

691

Q1X8D7
RIKQKGEYLPLLQGK

OTC

66

P00480
QYKLKVEKQLGLRPS

NEK5

416

Q6P3R8
VQKYLPGKIKVIRNT

GALNT11

206

Q8NCW6
QFQLRGKPKAKYLVR

NDNF

406

Q8TB73
QYKPGQRKSGSLQIK

MANSC4

316

A6NHS7
YQVPRKGIQAKEVLK

GBP2

446

P32456
LNNGPQRIGRKYKKV

F8

431

P00451
IIRQKPVDLLKYNQK

PLCG2

966

P16885
LNPLIYTLRNKKVKG

OR2I1P

286

Q8NGU4
QIYIVGRPTKKLQQQ

PITPNM2

1226

Q9BZ72
IRKIQKVVNTYTPGK

HPSE2

361

Q8WWQ2
KKKLREYQQRNSPGV

GOLGA2

26

Q08379
PGYIKLRKIRAAQNI

PHB2

246

Q99623
GNQIIYKLQTKRKLP

OLFML1

386

Q6UWY5
VLQNIYKVLKPGKSV

METTL6

171

Q8TCB7
LKPGVLLIYKTQKNG

OSBPL8

171

Q9BZF1
QKKAAQIKRRYTNPI

KAT6A

321

Q92794
YTNPIGRPKNRLKKQ

KAT6A

331

Q92794
VGASQDIIPQLKKKY

COMT

166

P21964
QLVQRLQGKILQYKK

CROCC

171

Q5TZA2
AKQPLQLKNRGKYEI

HYDIN

3066

Q4G0P3
FNKKLITGIIYPQNK

CAPN7

306

Q9Y6W3
LNKTYQNLKRKPVAV

DNAH17

2141

Q9UFH2
YKIVPNVLLEQGKAK

CS

381

O75390
PLLVKIQKQTYKFRN

ANKMY1

216

Q9P2S6
QRKGILKNRLQYPLV

CELSR3

3006

Q9NYQ7
QKLLKVPKGSIGQYI

CYLD

36

Q9NQC7
KLVPVGYGIKKLQIQ

EEF1B2

176

P24534
TYGKLVKLLSPKQQQ

PEX1

331

O43933
PYIVNIKGQRIKKSV

NOA1

661

Q8NC60
NKYPPINLKIKCNRL

COL6A6

2171

A6NMZ7
QSKNLYKIPLRNLVG

GARNL3

846

Q5VVW2
YNTKKIGKRLNIQLK

PARD3

451

Q8TEW0
RYSQKLKKKIQVQQP

PGBD3

436

Q8N328
KSKQYVKVQIPGLEN

MAP3K4

846

Q9Y6R4
NYRLKSLIKKGPNQG

TAF9B

126

Q9HBM6
TRYNKIKAIPIQQRK

UTRN

1841

P46939
RVIQKKYATGKPDQK

STARD13

831

Q9Y3M8
EGAQYRKKQLAKQLP

TES

141

Q9UGI8
QQKKKTSPLNYKERL

TEC

16

P42680
PPQVKDQKKLYLNRV

RESF1

1571

Q9HCM1
KPYITINNLKPRENK

PSG8

241

Q9UQ74
ILKQKAPQQYRIRAK

POT1

351

Q9NUX5
LQIYRRLGKPKITQS

CD84

126

Q9UIB8
VGIRLNKHKPNIYFK

DRG2

166

P55039
KQKYPEQQGRFAKLL

RXRB

476

P28702
KPLTQKRKLRIYISN

SMARCD2

186

Q92925
GTLKQNIPRLKLTYK

SEMA3D

36

O95025
LNKPGLKYKPVTNQV

AKR1B15

171

C9JRZ8
VILKGLARPQTNVYK

CNBD1

201

Q8NA66
KITIPKQQRYGKGII

PLA1A

371

Q53H76
PLLKAQEYIRQKNKG

PDCD11

216

Q14690
QKTKKQDIPRQLVYI

TRAM1L1

186

Q8N609
VSAYKNLQIKPGIKI

SLC26A2

566

P50443
LNQKRPQYIKAKENT

SMC1B

291

Q8NDV3
KKAYRLGSQKPVQRA

TONSL

266

Q96HA7
QIYKLAKKGLTPSQI

RPS13

36

P62277
KGLKTGYRAVPLKNN

PLCG1

1181

P19174
LNQKRPQYIKAKENT

SMC1A

291

Q14683
KGTGPNRKLIYNFKQ

SIRPD

66

Q9H106
NNLYIAGRLQKPVKI

TAMM41

126

Q96BW9
KRQGVKKLLGQYIPL

SPOCK3

326

Q9BQ16
QRPENKGKNRYKNIL

PTPN6

266

P29350
QLLNQPKITADKRYK

ZNF354A

201

O60765
RKKAPQKAEIYLQGA

TRAPPC10

491

P48553
LKINPKRYKGNFLQS

ZNF831

1286

Q5JPB2
VPKIKGNRKYQRPTV

TMEM202

16

A6NGA9
DLSQYVIGPKNNLKK

USP8

1036

P40818
KQQGVLALRPYLQKQ

MARS1

191

P56192