Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nuclear receptor activity	NR4A2 NR4A3 NR3C2 NR4A1	4.52e-06	60	37	4	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	NR4A2 NR4A3 NR3C2 NR4A1	4.83e-06	61	37	4	GO:0098531
GeneOntologyMolecularFunction	nuclear glucocorticoid receptor binding	NR4A2 NR4A3 NR4A1	6.53e-06	20	37	3	GO:0035259
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF711 NR4A2 GCM1 POU2F2 NR4A3 NR3C2 NR4A1 ZNF317 CXXC1 ZFY ZNF837	1.22e-05	1271	37	11	GO:0000987
GeneOntologyMolecularFunction	acetylcholine receptor regulator activity	SPDYE7P SPDYE16 SPDYE3	1.66e-05	27	37	3	GO:0030548
GeneOntologyMolecularFunction	neurotransmitter receptor regulator activity	SPDYE7P SPDYE16 SPDYE3	1.86e-05	28	37	3	GO:0099602
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF711 NR4A2 NFXL1 GCM1 POU2F2 NR4A3 NR3C2 NR4A1 ZNF317 ZFY ZNF837	3.27e-05	1412	37	11	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF711 NR4A2 NFXL1 GCM1 POU2F2 NR4A3 NR3C2 NR4A1 ZNF317 ZFY ZNF837	4.42e-05	1459	37	11	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF711 NR4A2 GCM1 POU2F2 NR4A3 NR3C2 NR4A1 ZNF317 ZFY ZNF837	6.28e-05	1244	37	10	GO:0000978
GeneOntologyMolecularFunction	zinc ion binding	NR4A2 NFXL1 GCM1 NR4A3 NR3C2 NR4A1 USP16 CXXC1	1.85e-04	891	37	8	GO:0008270
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	NR4A2 GCM1 POU2F2 NR4A3 NR4A1 ZFY	5.25e-04	560	37	6	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	NR4A2 GCM1 POU2F2 NR4A3 NR4A1 ZFY	5.56e-04	566	37	6	GO:0001216
GeneOntologyMolecularFunction	nuclear steroid receptor activity	NR4A3 NR3C2	9.76e-04	25	37	2	GO:0003707
GeneOntologyMolecularFunction	transition metal ion binding	NR4A2 NFXL1 GCM1 NR4A3 NR3C2 NR4A1 USP16 CXXC1	1.27e-03	1189	37	8	GO:0046914
GeneOntologyMolecularFunction	histone acetyltransferase binding	NR4A3 NR3C2	1.31e-03	29	37	2	GO:0035035
GeneOntologyMolecularFunction	heparan sulfate proteoglycan binding	LRP1 SLIT1	1.31e-03	29	37	2	GO:0043395
GeneOntologyMolecularFunction	proteoglycan binding	LRP1 SLIT1	4.02e-03	51	37	2	GO:0043394
GeneOntologyMolecularFunction	transcription coactivator binding	NR4A3 NR3C2	4.50e-03	54	37	2	GO:0001223
GeneOntologyMolecularFunction	nuclear receptor binding	NR4A2 NR4A3 NR4A1	4.97e-03	187	37	3	GO:0016922
GeneOntologyMolecularFunction	protein kinase binding	CD44 NR4A3 SPDYE18 SPDYE7P SPDYE16 SPDYE3	5.00e-03	873	37	6	GO:0019901
GeneOntologyMolecularFunction	signaling receptor regulator activity	MICA SPDYE7P WFIKKN2 SPDYE16 SPDYE3	5.30e-03	616	37	5	GO:0030545
GeneOntologyBiologicalProcess	cellular response to corticotropin-releasing hormone stimulus	NR4A2 NR4A3 NR4A1	9.73e-08	6	36	3	GO:0071376
GeneOntologyBiologicalProcess	response to corticotropin-releasing hormone	NR4A2 NR4A3 NR4A1	9.73e-08	6	36	3	GO:0043435
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein kinase activity	TTBK1 SPDYE7P SPDYE16 SPDYE3	1.55e-07	28	36	4	GO:1904031
GeneOntologyBiologicalProcess	regulation of peptidase activity	CD44 LRP1 NLRP1 TTBK1 NR4A1 ACVR1C WFIKKN2	5.54e-06	406	36	7	GO:0052547
GeneOntologyBiologicalProcess	regulation of monocyte aggregation	CD44 NR4A3	8.88e-06	3	36	2	GO:1900623
GeneOntologyBiologicalProcess	positive regulation of monocyte aggregation	CD44 NR4A3	8.88e-06	3	36	2	GO:1900625
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein serine/threonine kinase activity	SPDYE7P SPDYE16 SPDYE3	1.09e-05	25	36	3	GO:0045737
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein kinase activity	TTBK1 SPDYE7P SPDYE16 SPDYE3	2.72e-05	100	36	4	GO:1904029
GeneOntologyBiologicalProcess	regulation of cysteine-type endopeptidase activity	CD44 NLRP1 TTBK1 NR4A1 ACVR1C	5.52e-05	238	36	5	GO:2000116
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ZNF711 NR4A2 PWWP2A GCM1 POU2F2 NR4A3 NR3C2 NR4A1 USP16 ZFY	9.42e-05	1390	36	10	GO:0045944
GeneOntologyBiologicalProcess	monocyte aggregation	CD44 NR4A3	1.06e-04	9	36	2	GO:0070487
GeneOntologyBiologicalProcess	positive regulation of molecular function	NR4A2 LRP1 NLRP1 DNAJB11 TTBK1 ACVR1C SPDYE7P WDR59 SPDYE16 SPDYE3	1.19e-04	1430	36	10	GO:0044093
GeneOntologyBiologicalProcess	positive regulation of protein metabolic process	CD44 LRP1 NLRP1 TTBK1 ACVR1C SPDYE7P USP16 WDR59 SPDYE16 SPDYE3	1.40e-04	1458	36	10	GO:0051247
GeneOntologyBiologicalProcess	regulation of cell cycle	NR4A3 TTBK1 NR4A1 SPDYE7P USP16 ZFY GAS2 SPDYE16 SPDYE3	2.36e-04	1256	36	9	GO:0051726
GeneOntologyBiologicalProcess	regulation of endopeptidase activity	CD44 NLRP1 TTBK1 NR4A1 ACVR1C	2.62e-04	332	36	5	GO:0052548
GeneOntologyBiologicalProcess	regulation of proteolysis	CD44 LRP1 NLRP1 TTBK1 NR4A1 ACVR1C WFIKKN2	2.67e-04	748	36	7	GO:0030162
GeneOntologyBiologicalProcess	response to peptide hormone	NR4A2 NR4A3 OTC NR3C2 NR4A1 ACVR1C	2.83e-04	530	36	6	GO:0043434
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	NR4A2 NLRP1 TTBK1 ACVR1C SPDYE7P WDR59 SPDYE16 SPDYE3	3.22e-04	1028	36	8	GO:0043085
GeneOntologyBiologicalProcess	positive regulation of protein kinase activity	TTBK1 SPDYE7P WDR59 SPDYE16 SPDYE3	3.34e-04	350	36	5	GO:0045860
GeneOntologyBiologicalProcess	negative regulation of peptidase activity	CD44 LRP1 NR4A1 WFIKKN2	4.76e-04	210	36	4	GO:0010466
GeneOntologyBiologicalProcess	leukocyte aggregation	CD44 NR4A3	4.97e-04	19	36	2	GO:0070486
GeneOntologyBiologicalProcess	regulation of type B pancreatic cell proliferation	NR4A3 NR4A1	6.09e-04	21	36	2	GO:0061469
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein serine/threonine kinase activity	SPDYE7P SPDYE16 SPDYE3	6.24e-04	96	36	3	GO:0000079
GeneOntologyBiologicalProcess	positive regulation of kinase activity	TTBK1 SPDYE7P WDR59 SPDYE16 SPDYE3	6.50e-04	405	36	5	GO:0033674
GeneOntologyBiologicalProcess	regulation of hydrolase activity	CD44 LRP1 NLRP1 TTBK1 NR4A1 ACVR1C WFIKKN2	7.00e-04	878	36	7	GO:0051336
GeneOntologyBiologicalProcess	intracellular receptor signaling pathway	NR4A2 NR4A3 NLRP1 NR3C2 NR4A1	7.34e-04	416	36	5	GO:0030522
GeneOntologyBiologicalProcess	astrocyte differentiation	LRP1 GCM1 TTBK1	8.10e-04	105	36	3	GO:0048708
Domain	Nuc_orph_rcpt	NR4A2 NR4A3 NR4A1	6.03e-09	3	35	3	IPR003070
Domain	zf-C4	NR4A2 NR4A3 NR3C2 NR4A1	1.59e-06	46	35	4	PF00105
Domain	NUCLEAR_REC_DBD_1	NR4A2 NR4A3 NR3C2 NR4A1	1.59e-06	46	35	4	PS00031
Domain	Znf_hrmn_rcpt	NR4A2 NR4A3 NR3C2 NR4A1	1.59e-06	46	35	4	IPR001628
Domain	ZnF_C4	NR4A2 NR4A3 NR3C2 NR4A1	1.59e-06	46	35	4	SM00399
Domain	NUCLEAR_REC_DBD_2	NR4A2 NR4A3 NR3C2 NR4A1	1.59e-06	46	35	4	PS51030
Domain	-	NR4A2 NR4A3 NR3C2 NR4A1	1.74e-06	47	35	4	1.10.565.10
Domain	HOLI	NR4A2 NR4A3 NR3C2 NR4A1	1.90e-06	48	35	4	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	NR4A2 NR4A3 NR3C2 NR4A1	1.90e-06	48	35	4	IPR000536
Domain	Hormone_recep	NR4A2 NR4A3 NR3C2 NR4A1	1.90e-06	48	35	4	PF00104
Domain	-	NR4A2 NR4A3 NR3C2 NR4A1	3.80e-06	57	35	4	3.30.50.10
Domain	Znf_NHR/GATA	NR4A2 NR4A3 NR3C2 NR4A1	4.08e-06	58	35	4	IPR013088
Domain	Transcrp_activ_Zfx/Zfy-dom	ZNF711 ZFY	1.02e-05	3	35	2	IPR006794
Domain	Zfx_Zfy_act	ZNF711 ZFY	1.02e-05	3	35	2	PF04704
Domain	Nuclear_hrmn_rcpt	NR4A2 NR4A3 NR4A1	8.66e-05	46	35	3	IPR001723
Domain	Speedy	SPDYE16 SPDYE3	1.86e-04	11	35	2	IPR020984
Domain	Spy1	SPDYE16 SPDYE3	1.86e-04	11	35	2	PF11357
Domain	Zinc_finger_PHD-type_CS	NFXL1 CXXC1	6.59e-03	65	35	2	IPR019786
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR4A2 NR4A3 NR3C2 NR4A1	1.96e-06	48	27	4	MM14987
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR4A2 NR4A3 NR3C2 NR4A1	2.93e-06	53	27	4	M8276
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZNF711 NR4A2 POU2F2 NR4A3 NR3C2 NR4A1 ZNF317 CXXC1	4.75e-04	1022	27	8	MM15436
Pubmed	Nuclear receptors of the NR4a family are not required for the development and function of follicular T helper cells.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	25899083
Pubmed	NR4A nuclear receptors support memory enhancement by histone deacetylase inhibitors.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	22996661
Pubmed	Altered NR4A Subfamily Gene Expression Level in Peripheral Blood of Parkinson's and Alzheimer's Disease Patients.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	27159982
Pubmed	Inhibition of adipocyte differentiation by Nur77, Nurr1, and Nor1.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	18945812
Pubmed	The nuclear receptors NUR77, NURR1 and NOR1 in obesity and during fat loss.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	22143616
Pubmed	Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	16873729
Pubmed	The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	25605333
Pubmed	Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	15964844
Pubmed	Relevance of the NR4A sub-family of nuclear orphan receptors in trophoblastic BeWo cell differentiation.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	28808448
Pubmed	The NR4A receptors Nurr1 and Nur77 are increased in human placenta from women with gestational diabetes.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	25199433
Pubmed	NR4A nuclear receptors in immunity and atherosclerosis.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	24005216
Pubmed	Minireview: What is Known about SUMOylation Among NR4A Family Members?	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	34437889
Pubmed	Stress and glucocorticoid regulation of NR4A genes in mice.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	24753204
Pubmed	Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	21621845
Pubmed	Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	10523643
Pubmed	Replicated association of the NR4A3 gene with smoking behaviour in schizophrenia and in bipolar disorder.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	20659174
Pubmed	Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	36482877
Pubmed	Nuclear receptor 4A (NR4A) family - orphans no more.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	25917081
Pubmed	FGF-8 stimulates the expression of NR4A orphan nuclear receptors in osteoblasts.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	18809462
Pubmed	NR4A transcription factors limit CAR T cell function in solid tumours.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	30814732
Pubmed	The NR4A orphan nuclear receptors: mediators in metabolism and diseases.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	25089663
Pubmed	Beta-adrenergic signaling regulates NR4A nuclear receptor and metabolic gene expression in multiple tissues.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	19465082
Pubmed	MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling.	NR4A2 NR4A3 NR4A1	1.20e-09	3	38	3	15910281
Pubmed	TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	31152140
Pubmed	Trained immunity induced by high-salt diet impedes stroke recovery.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	37965920
Pubmed	Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	23334790
Pubmed	Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	37961948
Pubmed	Dual function of Pin1 in NR4A nuclear receptor activation: enhanced activity of NR4As and increased Nur77 protein stability.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	22789442
Pubmed	Nr4a Receptors Regulate Development and Death of Labile Treg Precursors to Prevent Generation of Pathogenic Self-Reactive Cells.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	30089271
Pubmed	Parathyroid hormone induces the NR4A family of nuclear orphan receptors in vivo.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	15910753
Pubmed	Vascular endothelial growth factor-regulated gene expression in endothelial cells: KDR-mediated induction of Egr3 and the related nuclear receptors Nur77, Nurr1, and Nor1.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	14525795
Pubmed	Regulation of peripheral Th/Treg differentiation and suppression of airway inflammation by Nr4a transcription factors.	NR4A2 NR4A3 NR4A1	4.81e-09	4	38	3	33665581
Pubmed	The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation.	NR4A2 NR4A3 NR4A1	1.20e-08	5	38	3	15155786
Pubmed	Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.	NR4A2 NR4A3 NR4A1	1.20e-08	5	38	3	26304965
Pubmed	Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1.	NR4A2 NR4A3 NR4A1	1.20e-08	5	38	3	8961274
Pubmed	NR4A receptors up-regulate the antiproteinase alpha-2 macroglobulin (A2M) and modulate MMP-2 and MMP-9 in vascular smooth muscle cells.	NR4A2 NR4A3 NR4A1	2.40e-08	6	38	3	25809189
Pubmed	Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation.	NR4A2 NR4A3 NR4A1	6.71e-08	8	38	3	16223362
Pubmed	Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.	SPDYE7P SPDYE16 SPDYE3	1.01e-07	9	38	3	36272447
Pubmed	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.	SPDYE7P SPDYE16 SPDYE3	3.42e-07	13	38	3	15611625
Pubmed	A census of human transcription factors: function, expression and evolution.	ZNF711 NR4A2 NFXL1 GCM1 POU2F2 NR4A3 NR3C2 NR4A1 ZFY	4.47e-07	908	38	9	19274049
Pubmed	TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.	NR4A2 NR4A3 NR4A1	5.43e-07	15	38	3	19321449
Pubmed	Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice.	NR4A2 NR4A3 NR4A1	6.67e-07	16	38	3	28170423
Pubmed	Characterization of a new family of cyclin-dependent kinase activators.	SPDYE7P SPDYE16 SPDYE3	8.10e-07	17	38	3	15574121
Pubmed	Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen Presentation and Viral Response.	NR4A2 NR4A3	1.16e-06	2	38	2	34248958
Pubmed	Compensatory Expression of Nur77 and Nurr1 Regulates NF-κB-Dependent Inflammatory Signaling in Astrocytes.	NR4A2 NR4A1	1.16e-06	2	38	2	30111648
Pubmed	Differential roles for Nr4a1 and Nr4a2 in object location vs. object recognition long-term memory.	NR4A2 NR4A1	1.16e-06	2	38	2	23161447
Pubmed	The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass.	NR4A3 NR4A1	1.16e-06	2	38	2	30696767
Pubmed	Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis.	NR4A3 NR4A1	1.16e-06	2	38	2	20411565
Pubmed	Nuclear receptors Nur77 and Nurr1 modulate mesenchymal stromal cell migration.	NR4A2 NR4A1	1.16e-06	2	38	2	21480782
Pubmed	NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.	NR4A3 NR4A1	1.16e-06	2	38	2	28249906
Pubmed	Molecular signatures of thyroid follicular neoplasia.	NR4A3 NR4A1	1.16e-06	2	38	2	20668010
Pubmed	LRP-1--CD44, a new cell surface complex regulating tumor cell adhesion.	CD44 LRP1	1.16e-06	2	38	2	22711991
Pubmed	The orphan nuclear receptors NURR1 and NGFI-B modulate aromatase gene expression in ovarian granulosa cells: a possible mechanism for repression of aromatase expression upon luteinizing hormone surge.	NR4A2 NR4A1	1.16e-06	2	38	2	15486232
Pubmed	A minority of cases of acinic cell carcinoma of the salivary glands are driven by an NR4A2 rearrangement: the diagnostic utility of the assessment of NR4A2 and NR4A3 alterations in salivary gland tumors.	NR4A2 NR4A3	1.16e-06	2	38	2	36469101
Pubmed	The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.	NR4A3 NR4A1	1.16e-06	2	38	2	25410408
Pubmed	Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury.	NR4A3 NR4A1	1.16e-06	2	38	2	19153266
Pubmed	Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia.	NR4A2 NR4A3	1.16e-06	2	38	2	38474099
Pubmed	HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML.	NR4A3 NR4A1	1.16e-06	2	38	2	23247046
Pubmed	Nur-related factor 1 and nerve growth factor-induced clone B in human adrenal cortex and its disorders.	NR4A2 NR4A1	1.16e-06	2	38	2	15292355
Pubmed	Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.	NR4A3 NR4A1	1.16e-06	2	38	2	17515897
Pubmed	Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice.	NR4A3 NR4A1	1.16e-06	2	38	2	21205929
Pubmed	Nuclear NR4A2 (Nurr1) Immunostaining is a Novel Marker for Acinic Cell Carcinoma of the Salivary Glands Lacking the Classic NR4A3 (NOR-1) Upregulation.	NR4A2 NR4A3	1.16e-06	2	38	2	32341238
Pubmed	Identification of a new brain-specific transcription factor, NURR1.	NR4A2 NR4A1	1.16e-06	2	38	2	1491694
Pubmed	NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival.	NR4A2 NR4A3	1.16e-06	2	38	2	28637666
Pubmed	Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia.	NR4A3 NR4A1	3.48e-06	3	38	2	23552735
Pubmed	Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair.	NR4A2 NR4A1	3.48e-06	3	38	2	21979916
Pubmed	Angiotensin II triggers expression of the adrenal gland zona glomerulosa-specific 3β-hydroxysteroid dehydrogenase isoenzyme through de novo protein synthesis of the orphan nuclear receptors NGFIB and NURR1.	NR4A2 NR4A1	3.48e-06	3	38	2	25092869
Pubmed	NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.	NR4A2 NR4A1	3.48e-06	3	38	2	7877627
Pubmed	NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling.	NR4A3 NR4A1	3.48e-06	3	38	2	29343483
Pubmed	Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor.	NR4A2 NR4A1	3.48e-06	3	38	2	15591535
Pubmed	Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.	ZNF711 ZFY	3.48e-06	3	38	2	32406922
Pubmed	Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis.	NR4A3 NR4A1	3.48e-06	3	38	2	20558821
Pubmed	Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis.	NR4A3 NR4A1	3.48e-06	3	38	2	9155013
Pubmed	Antithrombotic Effects of Nur77 and Nor1 Are Mediated Through Upregulating Thrombomodulin Expression in Endothelial Cells.	NR4A3 NR4A1	3.48e-06	3	38	2	26634653
Pubmed	Orphan nuclear receptors in T lymphocyte development.	NR4A3 NR4A1	3.48e-06	3	38	2	12223510
Pubmed	Mesenchymal COX2-PG secretome engages NR4A-WNT signalling axis in haematopoietic progenitors to suppress anti-leukaemia immunity.	NR4A2 NR4A1	3.48e-06	3	38	2	30106181
Pubmed	Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma.	CD44 MICA	3.48e-06	3	38	2	19826051
Pubmed	B cell lymphoma 2 (Bcl-2) residues essential for Bcl-2's apoptosis-inducing interaction with Nur77/Nor-1 orphan steroid receptors.	NR4A3 NR4A1	3.48e-06	3	38	2	29414782
Pubmed	Selective ligand activity at Nur/retinoid X receptor complexes revealed by dimer-specific bioluminescence resonance energy transfer-based sensors.	NR4A2 NR4A1	3.48e-06	3	38	2	26148973
Pubmed	NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment.	NR4A2 NR4A1	6.96e-06	4	38	2	38451819
Pubmed	Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice.	NR4A3 NR4A1	6.96e-06	4	38	2	23288947
Pubmed	Characterization of multiple sclerosis traits: nuclear receptors (NR) impaired apoptosis pathway and the role of 1-α 25-dihydroxyvitamin D3.	NR4A3 NR4A1	6.96e-06	4	38	2	21752397
Pubmed	Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells.	NR4A2 NR4A1	6.96e-06	4	38	2	18292087
Pubmed	NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection.	NR4A2 NR4A3	6.96e-06	4	38	2	20566846
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	NR4A2 POU2F2 NR4A3 NR3C2 NR4A1	9.74e-06	263	38	5	20932939
Pubmed	A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.	NR4A2 NR4A1	1.16e-05	5	38	2	7705655
Pubmed	The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells.	NR4A2 NR4A1	1.16e-05	5	38	2	21468021
Pubmed	NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting.	NR4A3 NR4A1	1.16e-05	5	38	2	32868928
Pubmed	Developmental dependence on NurRE and EboxNeuro for expression of pituitary proopiomelanocortin.	NR4A2 NR4A1	1.16e-05	5	38	2	18388149
Pubmed	Involvement of Nurr-1/Nur77 in corticotropin-releasing factor/urocortin1-induced tyrosinase-related protein 1 gene transcription in human melanoma HMV-II cells.	NR4A2 NR4A1	1.16e-05	5	38	2	23416839
Pubmed	Nr4a1 and Nr4a3 Reporter Mice Are Differentially Sensitive to T Cell Receptor Signal Strength and Duration.	NR4A3 NR4A1	1.16e-05	5	38	2	33147449
Pubmed	The nuclear receptor Nor-1 is essential for proliferation of the semicircular canals of the mouse inner ear.	NR4A2 NR4A3	1.74e-05	6	38	2	11784868
Pubmed	Maternal bile acid transporter deficiency promotes neonatal demise.	NR4A2 NR4A3 NR4A1	3.75e-05	59	38	3	26416771
Pubmed	A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells.	NR4A2 NR4A1	4.16e-05	9	38	2	22539306
Pubmed	Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing.	CD44 GAS2	6.35e-05	11	38	2	33964205
Pubmed	The construction of human somatic cell hybrids containing portions of the mouse X chromosome and their use to generate DNA probes via interspersed repetitive sequence polymerase chain reaction.	OTC ZFY	7.62e-05	12	38	2	1916827
Pubmed	Motor phenotypes and molecular networks associated with germline deficiency of Ciz1.	NR4A2 NR4A1	7.62e-05	12	38	2	27163549
Pubmed	Localization of murine X and autosomal sequences homologous to the human Y located testis-determining region.	OTC ZFY	9.00e-05	13	38	2	2721933
Pubmed	Complement factor H, a marker of self protects against experimental autoimmune encephalomyelitis.	CD44 LRP1	1.05e-04	14	38	2	19299737
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	NR4A2 POU2F2 NR4A3 NR3C2 NR4A1 ZFY	1.11e-04	709	38	6	22988430
Interaction	SPDYE3 interactions	SPDYE7P SPDYE3	9.30e-06	3	36	2	int:SPDYE3
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE18 SPDYE7P SPDYE16	1.47e-03	271	38	3	chr7q11
Cytoband	7q11.23	SPDYE18 SPDYE7P	2.96e-03	97	38	2	7q11.23
GeneFamily	Nuclear hormone receptors	NR4A2 NR4A3 NR3C2 NR4A1	6.81e-07	49	26	4	71
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE7P SPDYE3	1.30e-04	12	26	2	756
GeneFamily	Mitochondrial ribosomal proteins	MRPS12 MRPS18B	5.72e-03	79	26	2	646
Coexpression	HE_LIM_SUN_FETAL_LUNG_C5_CD5_NEG_MATURE_B_CELL	CD44 NR4A2 NR4A3 NR4A1	8.66e-07	52	37	4	M45780
Coexpression	UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN	NR4A2 NR4A3 NR4A1	1.79e-05	36	37	3	M9162
Coexpression	BROWNE_HCMV_INFECTION_2HR_UP	NR4A2 NR4A3 NR4A1	2.47e-05	40	37	3	M3649
Coexpression	CUI_DEVELOPING_HEART_VALVAR_ENDOTHELIAL_CELL	CD44 NR4A2 NR4A3 NR4A1	4.37e-05	139	37	4	M39322
Coexpression	JIANG_MELANOMA_TRM11_CD8	NR4A2 NR4A3 NR4A1	4.56e-05	49	37	3	M48975
Coexpression	JIANG_MELANOMA_TRM2_CD8	CD44 NR4A2 NR4A3 NR4A1	5.29e-05	146	37	4	M48966
Coexpression	NAGASHIMA_EGF_SIGNALING_UP	NR4A2 NR4A3 NR4A1	7.19e-05	57	37	3	M16311
Coexpression	GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP	CD44 POU2F2 NR4A1 CXXC1	1.04e-04	174	37	4	M380
Coexpression	PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5	NR4A2 NR4A1	1.06e-04	11	37	2	M2411
Coexpression	JIANG_MELANOMA_TRM1_CD8	CD44 NR4A2 NR4A3 NR4A1	1.12e-04	177	37	4	M48965
Coexpression	GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP	NLRP1 NR3C2 CXXC1 WDR59	1.12e-04	177	37	4	M5641
Coexpression	GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN	ZNF711 NR4A2 NR4A3 NR4A1	1.16e-04	179	37	4	M4259
Coexpression	JIANG_MELANOMA_TRM5_CD8	CD44 NR4A2 NR4A3 NR4A1	1.44e-04	189	37	4	M48969
Coexpression	DURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_MAST_CELLS	CD44 NR4A2 NR4A3	1.57e-04	74	37	3	M39294
Coexpression	ODONNELL_METASTASIS_UP	NLRP1 NR4A1 RAI1	1.70e-04	76	37	3	M265
Coexpression	GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_DN	NR4A3 NR4A1 MRPS12 CXXC1	1.78e-04	200	37	4	M7058
Coexpression	HALLMARK_TNFA_SIGNALING_VIA_NFKB	CD44 NR4A2 NR4A3 NR4A1	1.78e-04	200	37	4	M5890
Coexpression	JIANG_MELANOMA_TRM4	CD44 NR4A2 NR4A3 NR4A1	1.89e-04	203	37	4	M48968
Coexpression	LEE_LIVER_CANCER_HEPATOBLAST	CD44 NR4A1	2.30e-04	16	37	2	M13123
Coexpression	YAGI_AML_WITH_INV_16_TRANSLOCATION	POU2F2 NR4A3 NLRP1 NR4A1 MRPS18B	2.67e-04	411	37	5	M1047
Coexpression	SAFFORD_T_LYMPHOCYTE_ANERGY	NR4A2 NR4A3 MICA	2.80e-04	90	37	3	M1644
Coexpression	KANG_IMMORTALIZED_BY_TERT_DN	CD44 NR4A3 NR4A1	3.92e-04	101	37	3	M1514
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_500	ZNF711 NR4A2 NR4A3 NR4A1	2.86e-06	62	34	4	gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_500
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#2_top-relative-expression-ranked_500	ZNF711 NR4A2 NR4A1	3.05e-05	38	34	3	gudmap_dev gonad_e11.5_F_GonMes_Sma_k2_500
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500	ZNF711 NR4A2 NFXL1 NR4A3 NR4A1 ACVR1C	5.68e-05	432	34	6	gudmap_dev gonad_e11.5_M_GonMes_Sma_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#4_top-relative-expression-ranked_500	NR4A2 NR4A3 NR4A1	8.32e-05	53	34	3	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_100	NR4A3 NR4A1	1.36e-04	11	34	2	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_100_k2
CoexpressionAtlas	dev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#3_top-relative-expression-ranked_500	ZNF711 NR4A2 NR4A1	1.60e-04	66	34	3	gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k3_500
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#2_top-relative-expression-ranked_1000	ZNF711 NR4A2 NR4A1	1.83e-04	69	34	3	gudmap_dev gonad_e11.5_M_GonMes_Sma_k2_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000	ZNF711 NR4A2 NR4A1	1.99e-04	71	34	3	gudmap_dev gonad_e11.5_F_GonMes_Sma_k3_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_1000	ZNF711 NR4A2 NR4A1	2.25e-04	74	34	3	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k4_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#4_top-relative-expression-ranked_200	NR4A3 NR4A1	2.58e-04	15	34	2	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k4
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	ZNF711 NR4A2 LRP1 NFXL1 NR4A3 NR4A1 ACVR1C	3.33e-04	849	34	7	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000	ZNF711 NR4A2 LRP1 NFXL1 NR4A3 NR4A1 ACVR1C	3.55e-04	858	34	7	gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_100	NR4A2 NR4A3 NR4A1	4.14e-04	91	34	3	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100
CoexpressionAtlas	Myeloid Cells, DC.103+11b-.Lu, MHCII+ CD11c+ CD103+ CD11b, Lung, avg-2	CD44 NR4A2 LRP1 NR4A3 NR4A1	4.20e-04	402	34	5	GSM854241_500
CoexpressionAtlas	Myeloid Cells, DC.103-11b+24+.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24+, Lung, avg-2	CD44 NR4A2 LRP1 NR4A3 NR4A1	4.30e-04	404	34	5	GSM854269_500
CoexpressionAtlas	Myeloid Cells, DC.103-11b+.Lv, CD45+ CD11c+ MHC-II + CD11b high CD103-, Liver, avg-3	CD44 NR4A2 LRP1 NR4A3 NR4A1	4.65e-04	411	34	5	GSM538239_500
CoexpressionAtlas	Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2	CD44 NR4A2 LRP1 NR4A3 NR4A1	4.80e-04	414	34	5	GSM854271_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#1_top-relative-expression-ranked_200	NR4A3 NR4A1	5.63e-04	22	34	2	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200_k1
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_500	ZNF711 NR4A2 NR4A3 NR4A1 ACVR1C	6.07e-04	436	34	5	gudmap_dev gonad_e11.5_F_GonMes_Sma_500
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#2_top-relative-expression-ranked_100	NR4A2 NR4A1	6.72e-04	24	34	2	gudmap_dev gonad_e11.5_F_GonMes_Sma_k2_100
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 LRP1 NFXL1 NR4A3 NR4A1	4.89e-09	171	36	6	5e93c76ee60f9d0590ebb140812653a5e1369417
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NR4A2 NR4A3 NR4A1 TNFAIP8L3 SPDYE3	2.02e-07	163	36	5	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD44 NR4A2 LRP1 POU2F2 NR4A1	4.91e-07	195	36	5	391d8e00dd5f988baa6dbda8414d3c020679ea2f
ToppCell	BAL-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NR4A2 POU2F2 NR4A3 NR4A1 TNFAIP8L3	5.16e-07	197	36	5	6f83fc049f38f3de6bc5180ad4b51ceb4d5dcdb6
ToppCell	Control-Myeloid-cDC\|Control / Disease group,lineage and cell class （2021.01.30）	NR4A2 POU2F2 NR4A3 NR4A1 TNFAIP8L3	5.16e-07	197	36	5	aef933107da42a763b35041c90950db07707c0cb
ToppCell	BAL-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NR4A2 POU2F2 NR4A3 NR4A1 TNFAIP8L3	5.16e-07	197	36	5	15e683f4a610aad3e06723747c8e56ca25f57414
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD44 NR4A2 LRP1 POU2F2 NR4A1	5.16e-07	197	36	5	c34d0d11c5c6154988b41e00aea169090cb09785
ToppCell	BAL-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NR4A2 POU2F2 NR4A3 NR4A1 TNFAIP8L3	5.16e-07	197	36	5	6ac50c02899531a25885749d5305da788dfa9dbc
ToppCell	BAL-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NR4A2 POU2F2 NR4A3 NR4A1 TNFAIP8L3	5.16e-07	197	36	5	513ada82bbbb6a624d89edaa54f8c4a303dfb5e7
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 NR4A3 NR4A1 ZNF837	7.14e-06	154	36	4	874b1220337276489a89fcc9a39bc81ba6b68baf
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NR4A2 NR4A3 NR4A1 TNFAIP8L3	7.51e-06	156	36	4	0f54d62c0fc08bbdd5ac743b2d5d748c3d1e6ef9
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NR4A2 POU2F2 NR4A3 NR4A1	8.72e-06	162	36	4	0fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NR4A2 NR4A3 NR4A1 TNFAIP8L3	8.93e-06	163	36	4	a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GALNT14 NR4A3 NR4A1 TNFAIP8L3	9.83e-06	167	36	4	f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCell	droplet-Kidney-nan-24m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD44 LRP1 POU2F2 NR4A1	9.83e-06	167	36	4	2ee1660be117e20f24557522345572d11cbee813
ToppCell	droplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD44 LRP1 POU2F2 NR4A1	1.03e-05	169	36	4	b059304543876f514d5c7214f1f0a2da00f10a67
ToppCell	droplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD44 LRP1 POU2F2 NR4A1	1.03e-05	169	36	4	945f737984c4de70a4e9c214053b005358053dd5
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD44 LRP1 TNFAIP8L3 ACVR1C	1.21e-05	176	36	4	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NR4A2 GALNT14 SLIT1 MCHR2	1.26e-05	178	36	4	b169aa5eaa51730daaec69c6bc58126be1592a50
ToppCell	3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 NR4A3 NR4A1	1.29e-05	179	36	4	40441de2d679733ecbf2145fabc3ed65a53310eb
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NR4A2 GALNT14 SLIT1 MCHR2	1.35e-05	181	36	4	3e3c903b522dced6bec5dc447cc3f8bf9a9749e3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NR4A2 GALNT14 SLIT1 MCHR2	1.35e-05	181	36	4	13270b6ba6a9c8e5681c6f40000c643ce1d9344a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NR4A2 GALNT14 SLIT1 MCHR2	1.38e-05	182	36	4	205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NR4A2 GALNT14 SLIT1 MCHR2	1.41e-05	183	36	4	01ad18f198195ce341bae01a1c8c253cc4607766
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 POU2F2 NR4A3	1.44e-05	184	36	4	b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCell	B_cells-Naive_B_cells_\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	NR4A2 POU2F2 NR4A3 NR4A1	1.57e-05	188	36	4	d1bc1316bbb8cfc39acc70f8680b14d19f536997
ToppCell	RA-14._Fibroblast_III\|RA / Chamber and Cluster_Paper	CD44 NR4A2 NR4A3 NR4A1	1.60e-05	189	36	4	46e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell	Hippocampus-Neuronal-Excitatory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NR4A2 NR4A3 ACVR1C SLIT1	1.60e-05	189	36	4	4b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCell	RA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	CD44 NR4A2 NR4A3 NR4A1	1.60e-05	189	36	4	b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-naive_B_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NR4A2 POU2F2 NR4A3 NR4A1	1.67e-05	191	36	4	a073d58154c801ec499fd969f42b7f1ee7f15d79
ToppCell	ILEUM-non-inflamed-(2)_B_cell-(2)_Memory_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD44 NR4A2 NR4A3 NR4A1	1.70e-05	192	36	4	37d0d0fdd6bc3114d546020b472b6df9392392f4
ToppCell	367C-Myeloid-Dendritic-cDC2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 NR4A3 NR4A1 TNFAIP8L3	1.74e-05	193	36	4	940e9a419d0de1f9e72b5cc9c86684057003be58
ToppCell	BAL-Control-Myeloid-MoAM-MoAM3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NR4A2 POU2F2 NR4A3 NR4A1	1.74e-05	193	36	4	837c61408462c519912ecf3b83fdc72cd85fe88f
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	CD44 NR4A2 NR4A3 NR4A1	1.74e-05	193	36	4	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	Control-Myeloid-MoAM3\|Control / Disease group,lineage and cell class （2021.01.30）	NR4A2 POU2F2 NR4A3 NR4A1	1.74e-05	193	36	4	97d2f12be43fc26efa84ac4c6119132928a123de
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	CD44 GALNT14 NR4A3 NR4A1	1.74e-05	193	36	4	ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCell	BAL-Control-Myeloid-MoAM-MoAM3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NR4A2 POU2F2 NR4A3 NR4A1	1.74e-05	193	36	4	e4ca3a3c2704cdc52e6ac3f25f14debf74226c29
ToppCell	BAL-Control-Myeloid-MoAM-MoAM3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NR4A2 POU2F2 NR4A3 NR4A1	1.74e-05	193	36	4	e54f8b6381b5a96758cff41ab12d6f60cfca29a9
ToppCell	BAL-Control-Myeloid-MoAM-MoAM3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NR4A2 POU2F2 NR4A3 NR4A1	1.74e-05	193	36	4	d81840e1322507552b7726bf7828309375162324
ToppCell	3'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 NR4A3 NR4A1	1.74e-05	193	36	4	c17e87c042ef095ac99fdd6facf3bc2886924dc4
ToppCell	P28-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CD44 NR4A2 NR4A3 NR4A1	1.77e-05	194	36	4	3c661c6768c3f05d2aba03d329adb257ca201b2d
ToppCell	Transplant_Alveoli_and_parenchyma-Immune-Neutrophils\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	NR4A2 POU2F2 NR4A3 NR4A1	1.77e-05	194	36	4	28571cf24b8a1d0ffb716167b977d420868cc874
ToppCell	BAL-Control-Myeloid-MoAM\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NR4A2 POU2F2 NR4A3 NR4A1	1.77e-05	194	36	4	125bf2909cf89133693bc7b865ca08955cf67a2e
ToppCell	BAL-Control-Myeloid-MoAM\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NR4A2 POU2F2 NR4A3 NR4A1	1.77e-05	194	36	4	a4523adbbd25c314809eed3414d66a5b323446e5
ToppCell	P15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CD44 NR4A2 NR4A3 NR4A1	1.77e-05	194	36	4	5f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCell	tumor_Lung\|World / Location, Cell class and cell subclass	CD44 NR4A2 NR4A3 NR4A1	1.77e-05	194	36	4	7e6b8a30f8d08252ad3f1df826d6f7c0ba997c2c
ToppCell	343B-Myeloid-Dendritic-cDC2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 NR4A3 NR4A1 TNFAIP8L3	1.77e-05	194	36	4	ccb04f0788c98e0f63f18b09484d75ac536412a1
ToppCell	343B-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 POU2F2 NR4A3 NR4A1	1.81e-05	195	36	4	d1ec768573929c717bb6b20ad5f26c4549cfcaed
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Neutrophil\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD44 LRP1 POU2F2 NR4A1	1.81e-05	195	36	4	d8d2467196d7b2ce0c2cf6782e03e6db141ed3bf
ToppCell	metastatic_Brain-Myeloid_cells-Microglia/Mac\|metastatic_Brain / Location, Cell class and cell subclass	NR4A2 LRP1 NR4A3 NR4A1	1.81e-05	195	36	4	ae48d493ebda5f87781181a3d1d73d8f84fc5e77
ToppCell	343B-Myeloid-Monocyte\|343B / Donor, Lineage, Cell class and subclass (all cells)	CD44 NR4A2 NR4A3 NR4A1	1.81e-05	195	36	4	169b4952118ca5ded55de928a1cf08721cdac193
ToppCell	metastatic_Brain-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	NR4A2 POU2F2 NR4A3 NR4A1	1.81e-05	195	36	4	79fd13a7dd9f07f86bcab280c0be1899a692fab2
ToppCell	343B-Myeloid-Monocyte-CD14+_Monocyte\|343B / Donor, Lineage, Cell class and subclass (all cells)	CD44 NR4A2 NR4A3 NR4A1	1.81e-05	195	36	4	b5ee368c97113432fc8fe742654cd538558f327c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD44 LRP1 POU2F2 NR4A1	1.81e-05	195	36	4	68b579258caf023570c3922269e831e27d847934
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	NR4A2 NR4A3 NR4A1 ZFY	1.81e-05	195	36	4	7fb5c0911ff09580515d1a1827d7249d6242630c
ToppCell	10x5'-Lung-Myeloid_Mac-Intermediate_macrophages\|Lung / Manually curated celltypes from each tissue	CD44 NR4A2 NR4A3 NR4A1	1.84e-05	196	36	4	fede2c605f7581ce2ea7a284cffffa1a3970d811
ToppCell	facs-Trachea\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR4A2 LRP1 NR4A3 NR4A1	1.84e-05	196	36	4	34020d6553309daa269dff05de0a8567211ea4d2
ToppCell	Control-Myeloid-DC2\|Control / Condition, Lineage and Cell class	NR4A2 POU2F2 NR4A3 NR4A1	1.84e-05	196	36	4	0ccc26c2811e4c8631e0abd8555b167ac1e7a982
ToppCell	facs-Trachea\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NR4A2 LRP1 NR4A3 NR4A1	1.84e-05	196	36	4	8209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCell	metastatic_Brain-Myeloid_cells-CD163+CD14+_DCs\|metastatic_Brain / Location, Cell class and cell subclass	NR4A2 POU2F2 NR4A3 NR4A1	1.84e-05	196	36	4	3cd96d5729b7030ba57f21f5231096d93ef30e56
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 POU2F2 NR4A3	1.88e-05	197	36	4	f431f11196dc4332933b5d71c7c7408d54c2dedc
ToppCell	3'-Broncho-tracheal-Immune_Myeloid\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 POU2F2 NR4A3	1.88e-05	197	36	4	d568354aff89ac84dd06360f19100ef578a041ed
ToppCell	Control-Myeloid-DC2\|Myeloid / Condition, Lineage and Cell class	NR4A2 POU2F2 NR4A3 NR4A1	1.88e-05	197	36	4	e0ee15188ff0d9df3c3b5ea523553ce18d223c33
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 POU2F2 NR4A3	1.88e-05	197	36	4	0c059476a8cdc6ac71a01d9c414295177f45f8de
ToppCell	normal_Lymph_Node-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	NR4A2 POU2F2 NR4A3 NR4A1	1.88e-05	197	36	4	2b3cd318c988364adcba4441444045914d58fe46
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_2\|COVID-19_Mild / Disease condition and Cell class	CD44 NR4A2 LRP1 NLRP1	1.88e-05	197	36	4	e844f660010d114d65bd814f3d3fccd8e4a6b8da
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_only / Treatment groups by lineage, cell group, cell type	NR4A2 NR4A3 NLRP1 NR4A1	1.92e-05	198	36	4	d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 POU2F2 NR4A3	1.92e-05	198	36	4	4b6767bd6fd4bd43eed18fd4a34c20923fa795da
ToppCell	Control-B_intermediate-0\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CD44 NR4A2 POU2F2 NR4A1	1.92e-05	198	36	4	6f7e0b8bc06368d6e7026d69473ddd42dd41cfcb
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 POU2F2 NR4A3	1.92e-05	198	36	4	18daf83309813f914b17bd226ea8a9269a26b107
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD44 NR4A2 POU2F2 NR4A3	1.92e-05	198	36	4	72c7474e084d1334a09c0a3b0f3c3137038794c8
ToppCell	mLN-B_cell-B_cell_memory\|B_cell / Region, Cell class and subclass	CD44 NR4A2 NR4A3 NR4A1	1.92e-05	198	36	4	e2c63ca9f82f8524447e398b11a676b22d2f58ce
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NR4A2 NR4A3 NR4A1 TNFAIP8L3	1.96e-05	199	36	4	e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCell	LPS_only\|World / Treatment groups by lineage, cell group, cell type	CD44 NR4A2 NR4A3 NR4A1	1.96e-05	199	36	4	852cf595c2255983cff9045f2bb746d4391cf5ba
ToppCell	LPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NR4A2 NR4A3 NLRP1 ZNF837	2.00e-05	200	36	4	6a34e07e6d77fe3fdd9ff44c4b1e46a023f6d6a2
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD44 NR4A2 NR4A3 NR4A1	2.00e-05	200	36	4	c30da72c3581d384b76c95f5989e32a36d783ef3
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Mast_cell\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CD44 NR4A2 NR4A3 NR4A1	2.00e-05	200	36	4	21de2cf284c8d2aa464f3d403f0e292e1f654e0a
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Mast_cell-Mast_cell\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CD44 NR4A2 NR4A3 NR4A1	2.00e-05	200	36	4	a338b2b94901e4614ef78e82f580b67891f7c849
ToppCell	Bronchus_Control_(B.)-Immune-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CD44 NR4A2 POU2F2 NR4A3	2.00e-05	200	36	4	ad0d38ffe5ca138b40823d15b239c2f9f3f0e93c
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NR4A2 LRP1 NR4A3 NR4A1	2.00e-05	200	36	4	09bac15df511687ff336c1e7a67d980c6c281f79
ToppCell	Myeloid-Myeloid-C_(Cd16+_Monocyte)\|Myeloid / shred on cell class and cell subclass (v4)	GALNT14 POU2F2 NR4A1	1.15e-04	117	36	3	d1936e76a935216783a73ab414e4147fa48e68eb
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-2\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	GALNT14 GCM1 SLIT1	1.40e-04	125	36	3	6cd741dd1c7ee6b16437cca7c15c99b5c95603fc
ToppCell	Enterocyte-C_02\|Enterocyte / shred on cell type and cluster	CD44 NR4A1 MRPS12	1.79e-04	136	36	3	daf11618c65e8fa2d77001b5c277d534cc012a4b
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-3\|TCGA-Breast / Sample_Type by Project: Shred V9	NR4A3 OTC NR4A1	1.83e-04	137	36	3	3218c787a6b087f74b0804cec14b5ebb713391b7
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Rrad\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NR4A2 NR4A3 NR4A1	1.87e-04	138	36	3	b3a040c5d0e1cc94d9b19155bca8700edba2d243
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALNT14 NR3C2 TNFAIP8L3	2.04e-04	142	36	3	ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 NR4A3 NR4A1	2.08e-04	143	36	3	091708a47ac55c6585923ee30190ff296fa87f6f
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NR4A3 NR4A1 TNFAIP8L3	2.12e-04	144	36	3	38ff324366ad5be626e3657c1e33277fc36ddd4c
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Serpinf1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALNT14 NR3C2 TNFAIP8L3	2.35e-04	149	36	3	5293c50b3fb41b1edaf9a97354899bd13770078c
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-4\|TCGA-Bladder / Sample_Type by Project: Shred V9	NR4A2 NR4A3 NR4A1	2.39e-04	150	36	3	bcb99c6fa81052556ab30f9db5875fccf1ae724b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CD44 NR4A3 SLIT1	2.49e-04	152	36	3	b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	NR4A2 NR4A3 NR4A1	2.68e-04	156	36	3	5df19a235843829f5a1a90ca21b0964ef8b4e115
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	NR4A2 NR4A3 NR4A1	2.68e-04	156	36	3	029ba0832ee9c4a2c85620e4df2260e02d86b45c
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NR4A3 NR4A1 ZNF837	2.73e-04	157	36	3	7ceae5fe00c91d4feb8c314d3a31f027c03fa56f
ToppCell	CD8+_Memory_T_cell-RSV-6\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	NR4A3 ACVR1C SPDYE3	2.79e-04	158	36	3	5ae737757a49fc96bde1e57e02066f9f65654ea1
ToppCell	343B-Myeloid-Mast_cell-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CD44 NR4A3 NR4A1	2.89e-04	160	36	3	a2f09b5955602819c8978f4372130c8ef915cd07
ToppCell	facs-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD44 POU2F2 NR4A1	2.89e-04	160	36	3	bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 POU2F2 NR4A1	2.89e-04	160	36	3	2020b6defbaf5b5db12af37f0103ac028a8ca76e
ToppCell	TCGA-Bladder-Solid_Tissue_Normal\|TCGA-Bladder / Sample_Type by Project: Shred V9	NR4A3 NR3C2 NR4A1	2.89e-04	160	36	3	d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue\|TCGA-Bladder / Sample_Type by Project: Shred V9	NR4A3 NR3C2 NR4A1	2.89e-04	160	36	3	8a41e2c96e0e170ac35daf6c403bf961b8d7c30b
Drug	fluorohydrocortisone	OTC NR3C2 MCHR2	2.23e-06	17	35	3	CID000247939
Drug	AC1L2X7C	NR3C2 NR4A1	2.30e-06	2	35	2	CID000104633
Drug	tosyl azide	NR3C2 NR4A1	2.30e-06	2	35	2	CID000013661
Drug	NOR-1	NR4A2 NR4A3 NR3C2 NR4A1	3.99e-06	70	35	4	CID006399012
Drug	Podophyllotoxin [518-28-5]; Up 200; 9.6uM; HL60; HT_HG-U133A	NR4A2 POU2F2 NR4A3 NLRP1 NR4A1	5.28e-06	166	35	5	2540_UP
Drug	Antigen-Antibody Complex	NR4A2 NR4A3 NR4A1	6.59e-06	24	35	3	ctd:D000936
Drug	Seneciphylline [480-81-9]; Up 200; 12uM; HL60; HT_HG-U133A	NR4A2 NR4A3 NLRP1 MRPS12 WDR59	1.21e-05	197	35	5	2140_UP
Drug	Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; PC3; HT_HG-U133A	NR4A2 LRP1 POU2F2 NR4A1 WDR59	1.24e-05	198	35	5	3703_UP
Drug	8-iso-prostaglandin A2	NR4A2 NR4A3 NR4A1	1.45e-05	31	35	3	CID000004953
Drug	ethyl pyruvate	LRP1 NLRP1 TNFAIP8L3	1.76e-05	33	35	3	CID000012041
Drug	EMCs	NR4A2 NR4A3 NR4A1	1.93e-05	34	35	3	CID005091655
Drug	18-VP	NR3C2 NR4A1	3.43e-05	6	35	2	CID000133557
Drug	18EP	NR3C2 NR4A1	3.43e-05	6	35	2	CID003082761
Drug	Calcimycin	NR4A2 NR4A3 OTC NR4A1	4.92e-05	132	35	4	ctd:D000001
Drug	Decortilen	NR3C2 NR4A1	6.39e-05	8	35	2	CID000011740
Drug	mespirenone	NR3C2 NR4A1	6.39e-05	8	35	2	CID000065660
Drug	sodium chlorate	CD44 LRP1 NR4A3	6.59e-05	51	35	3	CID000516902
Drug	shikonin	NR4A2 NR4A3 NR4A1	6.59e-05	51	35	3	ctd:C016101
Drug	N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine	NR4A3 NR4A1	8.21e-05	9	35	2	ctd:C518313
Drug	Puromycin dihydrochloride [58-58-2]; Up 200; 7.4uM; HL60; HT_HG-U133A	NR4A2 POU2F2 NR4A3 NR4A1	8.29e-05	151	35	4	2448_UP
Drug	thioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA	CD44 NR4A2 NR4A3 NR4A1	9.18e-05	155	35	4	1068_UP
Drug	Dichlorodiphenyl Dichloroethylene	CD44 NR4A2 NR4A1 ACVR1C SLIT1	9.30e-05	302	35	5	ctd:D003633
Drug	Suloctidil [54063-56-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A	NR4A2 NR4A3 NR4A1 WDR59	9.65e-05	157	35	4	2651_UP
Drug	1-amino-2-ethylcyclopropane-1-carboxylate	NLRP1 OTC	1.03e-04	10	35	2	CID000133485
Drug	AC1ODU4J	NLRP1 OTC	1.03e-04	10	35	2	CID000151277
Drug	Proscillaridin A [466-06-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A	NR4A2 POU2F2 NR4A3 NR4A1	1.04e-04	160	35	4	4404_UP
Drug	Proscillaridin A [466-06-8]; Up 200; 7.6uM; HL60; HT_HG-U133A	NR4A2 NR4A3 NLRP1 NR4A1	1.14e-04	164	35	4	2920_UP
Drug	Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; HL60; HT_HG-U133A	NR4A2 POU2F2 NR4A3 NR4A1	1.20e-04	166	35	4	2446_UP
Drug	Strophanthidin [66-28-4]; Up 200; 9.8uM; HL60; HT_HG-U133A	NR4A2 NR4A3 NLRP1 NR4A1	1.20e-04	166	35	4	2525_UP
Drug	Sanguinarine [2447-54-3]; Up 200; 12uM; HL60; HT_HG-U133A	NR4A2 GCM1 NR4A3 NR4A1	1.22e-04	167	35	4	2927_UP
Drug	geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A	NR4A2 LRP1 NR4A3 NR4A1	1.22e-04	167	35	4	6187_UP
Drug	Pyrvinium pamoate [3546-41-6]; Up 200; 3.4uM; HL60; HT_HG-U133A	CD44 NR4A2 NR4A3 NR4A1	1.34e-04	171	35	4	2957_UP
Drug	Colchicine [64-86-8]; Up 200; 10uM; HL60; HG-U133A	CD44 NR4A2 NR4A3 NR4A1	1.34e-04	171	35	4	1598_UP
Drug	Hexetidine [141-94-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A	CD44 NR4A2 NR4A3 NR4A1	1.34e-04	171	35	4	3318_UP
Drug	Fluspirilen [1841-19-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A	CD44 NR4A2 NR4A3 NR4A1	1.53e-04	177	35	4	6463_UP
Drug	Miconazole [22916-47-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A	CD44 NR4A2 NR4A3 NR4A1	1.63e-04	180	35	4	1477_UP
Drug	Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; HL60; HT_HG-U133A	NR4A2 NR4A3 NR4A1 WDR59	1.70e-04	182	35	4	1280_UP
Drug	Fendiline hydrochloride [13636-18-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A	NR4A2 LRP1 NR4A3 NR4A1	1.74e-04	183	35	4	3190_UP
Drug	N-acetylpenicillamine	NR4A3 NLRP1	1.77e-04	13	35	2	CID000027372
Drug	Sanguinarine [2447-54-3]; Up 200; 12uM; MCF7; HT_HG-U133A	ZNF711 NR4A2 GCM1 NR4A3	1.81e-04	185	35	4	4168_UP
Drug	2-propylpentanoic acid; Up 200; 1000uM; ssMCF7; HG-U133A	CD44 POU2F2 NR4A1 SSUH2	2.05e-04	191	35	4	497_UP
Drug	Luteolin [491-70-3]; Up 200; 14uM; HL60; HT_HG-U133A	NR4A2 GCM1 NR4A3 NR4A1	2.09e-04	192	35	4	3041_UP
Drug	pseudococaine	CD44 NR4A2 NR4A3 NLRP1 NR4A1 TNFAIP8L3	2.10e-04	570	35	6	CID000002826
Drug	Resveratrol [501-36-0]; Up 200; 17.6uM; HL60; HG-U133A	NR4A2 POU2F2 NR4A3 NR4A1	2.13e-04	193	35	4	1715_UP
Drug	Estrone [53-16-7]; Up 200; 14.8uM; HL60; HT_HG-U133A	NLRP1 NR4A1 WDR59 GAS2	2.18e-04	194	35	4	3071_UP
Drug	Iopromide [73334-07-3]; Down 200; 5uM; HL60; HT_HG-U133A	NR4A2 NLRP1 MRPS12 GAS2	2.18e-04	194	35	4	2739_DN
Drug	Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A	NR4A2 POU2F2 NR4A3 NR4A1	2.22e-04	195	35	4	3890_UP
Drug	S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; HL60; HT_HG-U133A	CD44 POU2F2 NLRP1 MRPS12	2.22e-04	195	35	4	3082_UP
Drug	Betulin [473-98-3]; Down 200; 9uM; HL60; HT_HG-U133A	NR4A2 NR4A3 NLRP1 NR4A1	2.26e-04	196	35	4	2952_DN
Drug	Famprofazone [22881-35-2]; Up 200; 10.6uM; HL60; HT_HG-U133A	NR4A2 NR4A3 NLRP1 WDR59	2.26e-04	196	35	4	2174_UP
Drug	0173570-0000 [211245-44-2]; Up 200; 10uM; PC3; HT_HG-U133A	NR4A2 LRP1 POU2F2 GAS2	2.26e-04	196	35	4	3690_UP
Drug	genistein; Up 200; 10uM; HL60; HT_HG-U133A	NR4A2 NR4A3 NR3C2 WDR59	2.26e-04	196	35	4	6194_UP
Drug	Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A	LRP1 POU2F2 NLRP1 WDR59	2.31e-04	197	35	4	2637_UP
Drug	1-phenylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A	LRP1 POU2F2 NLRP1 NR4A1	2.31e-04	197	35	4	22_DN
Drug	Finasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A	NR4A2 LRP1 POU2F2 NLRP1	2.31e-04	197	35	4	3744_UP
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	NR4A2 LRP1 GALNT14 NR4A1	2.31e-04	197	35	4	2075_UP
Drug	Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; HL60; HT_HG-U133A	NR4A2 NLRP1 NR4A1 WDR59	2.31e-04	197	35	4	3008_UP
Drug	Novobiocin sodium salt [1476-53-5]; Down 200; 6.4uM; PC3; HT_HG-U133A	NR4A2 LRP1 GALNT14 WDR59	2.35e-04	198	35	4	4569_DN
Drug	Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; HL60; HT_HG-U133A	NR4A2 POU2F2 NLRP1 MRPS12	2.35e-04	198	35	4	2158_UP
Drug	Meticrane [1084-65-7]; Up 200; 14.6uM; MCF7; HT_HG-U133A	POU2F2 NR4A1 WDR59 GAS2	2.35e-04	198	35	4	1671_UP
Drug	mosapramine	NLRP1 ZFY	2.38e-04	15	35	2	CID000004257
Drug	dalcetrapib	NR4A2 NR3C2	2.38e-04	15	35	2	ctd:C411602
Drug	Org 2766	NLRP1 NR3C2	2.38e-04	15	35	2	CID000104992
Drug	Nifurtimox [23256-30-6]; Up 200; 14uM; PC3; HT_HG-U133A	NR4A2 GALNT14 POU2F2 NR4A1	2.40e-04	199	35	4	6608_UP
Drug	MK-886	NLRP1 TNFAIP8L3 MCHR2	2.43e-04	79	35	3	CID003651377
Drug	Pentylenetetrazole	NR4A2 LRP1 NR4A1 MRPS18B	2.44e-04	200	35	4	ctd:D010433
Drug	penten	NR4A2 NR4A1	2.72e-04	16	35	2	CID000008004
Drug	dexamethasone 21-mesylate	NR3C2 NR4A1	2.72e-04	16	35	2	CID000063041
Drug	lotion	GCM1 NLRP1 OTC	2.91e-04	84	35	3	CID000001176
Drug	SR-202	NR4A2 NR4A1	3.08e-04	17	35	2	CID000060910
Drug	AC1L1WZD	NR4A2 NR4A1	3.08e-04	17	35	2	CID000062368
Drug	NL-2	NR4A2 NR3C2	3.46e-04	18	35	2	CID011846801
Drug	mecillinam	OTC MRPS12	3.86e-04	19	35	2	CID000036273
Drug	anacetrapib	NR4A2 NR3C2	3.86e-04	19	35	2	ctd:C530884
Drug	isocycloheximide	CD44 NR4A2 LRP1 NLRP1 NR3C2 NR4A1 TNFAIP8L3	3.88e-04	905	35	7	CID000002900
Drug	11 alpha-hydroxyprogesterone	NR3C2 NR4A1	4.29e-04	20	35	2	CID000092730
Drug	Hypertensin II	LRP1 NLRP1 NR3C2 TNFAIP8L3 ACVR1C	4.73e-04	429	35	5	CID000025476
Drug	N-acetylcysteamine	NR4A3 NLRP1	4.73e-04	21	35	2	CID000014484
Drug	AC1L9Q7L	NR3C2 NR4A1	4.73e-04	21	35	2	CID000452291
Disease	DnaJ homolog subfamily B member 11 measurement	DNAJB11 MICA	1.81e-05	6	33	2	EFO_0801537
Disease	Major Depressive Disorder	NR4A2 LRP1 NR3C2 NR4A1	1.52e-04	243	33	4	C1269683
Disease	sensorineural hearing loss (implicated_via_orthology)	MRPS12 GAS2	2.05e-04	19	33	2	DOID:10003 (implicated_via_orthology)
Disease	pallidum volume change measurement, age at assessment	MICA SLIT1	3.58e-04	25	33	2	EFO_0008007, EFO_0021494
Disease	birth weight, parental genotype effect measurement	MICA ACVR1C RAI1	1.28e-03	192	33	3	EFO_0004344, EFO_0005939
Disease	cholestasis (biomarker_via_orthology)	CD44 OTC	1.38e-03	49	33	2	DOID:13580 (biomarker_via_orthology)
Disease	birth weight, pelvic organ prolapse	WDR59 SLIT1	1.38e-03	49	33	2	EFO_0004344, EFO_0004710
Disease	Insulin Sensitivity	NR4A3 NR4A1	2.06e-03	60	33	2	C0920563
Disease	Insulin Resistance	NR4A3 NR4A1	2.06e-03	60	33	2	C0021655
Disease	Arsenic Induced Polyneuropathy	CD44 NR4A2	2.20e-03	62	33	2	C0751852
Disease	Arsenic Encephalopathy	CD44 NR4A2	2.20e-03	62	33	2	C0751851
Disease	Arsenic Poisoning	CD44 NR4A2	2.20e-03	62	33	2	C0311375
Disease	Arsenic Poisoning, Inorganic	CD44 NR4A2	2.20e-03	62	33	2	C0274861
Disease	Nervous System, Organic Arsenic Poisoning	CD44 NR4A2	2.20e-03	62	33	2	C0274862
Disease	Unipolar Depression	NR4A2 LRP1 NR3C2	3.00e-03	259	33	3	C0041696
Disease	Dermatologic disorders	CD44 NR4A2	3.20e-03	75	33	2	C0037274
Disease	Nerve Degeneration	CD44 OTC	3.90e-03	83	33	2	C0027746
Disease	psoriatic arthritis	MICA MRPS18B	4.28e-03	87	33	2	EFO_0003778
Disease	descending aortic diameter	LRP1 MICA	4.37e-03	88	33	2	EFO_0021788

Protein segments in the cluster

Peptide	Gene	Start	Entry
CQGRQCSYRKKKRPN	ACVR1C	136	Q8NER5
SPCKGRAKRRRQQQV	RAI1	1551	Q7Z5J4
FLRCDRQKCRAKPQG	MICA	56	Q29983
NKDCPVDKRRRNRCQ	NR4A1	306	P22736
RRKNCPACRLQKCLQ	NR3C2	651	P08235
NCNQKVKLRCPCKRI	NFXL1	791	Q6ZNB6
FLNARRQPKCRCQPR	LRP1	4211	Q07954
RCGQPLQNKVQLKGR	OTC	26	P00480
CQRLRQPSCKLQRLQ	NLRP1	886	Q9C000
CNRRQKEKRINPCSA	POU2F2	346	P09086
PKVKCLRNNERQGLV	GALNT14	166	Q96FL9
NKDARCCNPSVPKQR	MCHR2	231	Q969V1
PNKIRQKCRLRQCQL	CXXC1	196	Q9P0U4
VCIAVNSRRRCGQKK	CD44	666	P16070
LRPAICDKARQKQQR	GCM1	96	Q9NP62
QKQQRKRCPNCDGPL	GCM1	106	Q9NP62
RQAPGKRKCNCRQEM	DNAJB11	161	Q9UBS4
ANKNCPVDKRRRNRC	NR4A2	301	P43354
NKNCPVDKRRRNRCQ	NR4A3	331	Q92570
KCPNKFCVERLSQGR	GAS2	216	O43903
NAIKLRPRQVLCDKC	PWWP2A	311	Q96N64
KKPNSANRKCCRVRL	MRPS12	71	O15235
KRKAKQSRRCQLCAG	SSUH2	206	Q9Y2M2
VCCKKRKPGQTGRNR	SHANK2-AS3	86	Q9BTD1
PCARCGKRFRPNQQQ	ZNF837	226	Q96EG3
RKTCIRRNKVVGNPC	MRPS18B	91	Q9Y676
DCRPNLKRICEGINK	TNFAIP8L3	271	Q5GJ75
NRNKLRINIGKSPCV	TTBK1	406	Q5TCY1
VCTRRQCNGPKANIK	USP16	656	Q9Y5T5
LCRCMNPRARKNRSQ	SPDYE16	251	A6NNV3
LCRCLNPRARKNRSQ	SPDYE18	291	P0DV79
FQLCRPMNPRARKNC	SPDYE3	486	A6NKU9
QLCRCMNPRARKNRS	SPDYE7P	146	Q495Y7
QKVKRGQSCLEPCLR	WDR59	471	Q6PJI9
LKCKRCKRGFRQQNE	ZNF711	676	Q9Y462
LRKRKIVTGNPRCQN	SLIT1	686	O75093
KPVECRQCGKTFRNQ	ZNF317	416	Q96PQ6
RCKRCRKGFRQQNEL	ZFY	716	P08048
GNQRCRACKPRQKLV	WFIKKN2	441	Q8TEU8