Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

TOGARAM2 MYO18A EZR PTPN3 CCDC88A SKA3 KIF27 MYH13 ANK3 MYO6 RAB27A MAEA

2.98e-0610994412GO:0008092
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO18A KIF27 MYH13 MYO6

1.31e-04118444GO:0003774
GeneOntologyMolecularFunctionmicrotubule binding

TOGARAM2 EZR CCDC88A SKA3 KIF27

5.61e-04308445GO:0008017
GeneOntologyMolecularFunctionactin binding

MYO18A EZR CCDC88A MYH13 MYO6 MAEA

6.02e-04479446GO:0003779
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MYO18A SEPTIN1 SEPTIN11 KIF27 ATAD2 SEPTIN5 RAB27A

1.41e-03775447GO:0017111
GeneOntologyMolecularFunctionGDP binding

CCDC88A SEPTIN5 RAB27A

1.51e-03103443GO:0019003
GeneOntologyMolecularFunctionprotein tyrosine phosphatase activity

PTPN3 PTPN14 DNAJC6

1.51e-03103443GO:0004725
GeneOntologyMolecularFunctionactin filament binding

MYO18A EZR MYH13 MYO6

1.55e-03227444GO:0051015
GeneOntologyMolecularFunctionpyrophosphatase activity

MYO18A SEPTIN1 SEPTIN11 KIF27 ATAD2 SEPTIN5 RAB27A

2.22e-03839447GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

MYO18A SEPTIN1 SEPTIN11 KIF27 ATAD2 SEPTIN5 RAB27A

2.24e-03840447GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

MYO18A SEPTIN1 SEPTIN11 KIF27 ATAD2 SEPTIN5 RAB27A

2.24e-03840447GO:0016818
GeneOntologyMolecularFunctiontubulin binding

TOGARAM2 EZR CCDC88A SKA3 KIF27

2.41e-03428445GO:0015631
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

SEPTIN1 SEPTIN11 CCDC88A SEPTIN5 RAB27A

2.69e-03439445GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

SEPTIN1 SEPTIN11 CCDC88A SEPTIN5 RAB27A

2.69e-03439445GO:0019001
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH13 MYO6

3.17e-0338442GO:0000146
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

CCDC88A SASH1

4.05e-0343442GO:0001965
GeneOntologyMolecularFunctionADP binding

MYO18A MYO6

5.02e-0348442GO:0043531
GeneOntologyBiologicalProcessmaintenance of protein location in membrane

CCDC88A ANK3

1.39e-053452GO:0072658
GeneOntologyBiologicalProcessmaintenance of protein location in plasma membrane

CCDC88A ANK3

1.39e-053452GO:0072660
GeneOntologyBiologicalProcesscytokinesis

SEPTIN1 SEPTIN11 RAB11FIP4 ANK3 SEPTIN5

7.98e-05204455GO:0000910
GeneOntologyBiologicalProcessregulation of vesicle-mediated transport

MYO18A UNC13B SEPTIN1 EZR ANK3 SEPTIN5 DNAJC6 RAB27A

8.58e-05667458GO:0060627
GeneOntologyBiologicalProcessregulation of membrane depolarization during action potential

PTPN3 ANK3

9.71e-057452GO:0098902
GeneOntologyBiologicalProcesscell division

SEPTIN1 SEPTIN11 SYCP2 RAB11FIP4 SKA3 ANK3 SEPTIN5 MAEA

1.16e-04697458GO:0051301
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

SEPTIN1 SEPTIN11 ANK3 SEPTIN5

1.68e-04127454GO:0061640
GeneOntologyCellularComponentcell division site

SEPTIN1 SEPTIN11 RAB11FIP4 SEPTIN5 MAEA

7.84e-0780455GO:0032153
GeneOntologyCellularComponentcell cortex

UNC13B SEPTIN1 EZR SEPTIN11 SEPTIN5 MYO6 SLC2A1 MAEA

1.11e-06371458GO:0005938
GeneOntologyCellularComponentactin cytoskeleton

MYO18A EZR SEPTIN11 MYH13 SEPTIN5 MYO6 SLC2A1 MAEA SMTNL2

3.15e-06576459GO:0015629
GeneOntologyCellularComponentseptin complex

SEPTIN1 SEPTIN11 SEPTIN5

3.34e-0614453GO:0031105
GeneOntologyCellularComponentseptin ring

SEPTIN1 SEPTIN11 SEPTIN5

3.34e-0614453GO:0005940
GeneOntologyCellularComponentseptin cytoskeleton

SEPTIN1 SEPTIN11 SEPTIN5

5.12e-0616453GO:0032156
GeneOntologyCellularComponentsupramolecular fiber

TOGARAM2 MYO18A EZR SKA3 KIF27 MYH13 ANK3 MYO6 SLC2A1 SMTNL2

1.64e-0411794510GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

TOGARAM2 MYO18A EZR SKA3 KIF27 MYH13 ANK3 MYO6 SLC2A1 SMTNL2

1.73e-0411874510GO:0099081
GeneOntologyCellularComponentmyosin complex

MYO18A MYH13 MYO6

2.79e-0459453GO:0016459
GeneOntologyCellularComponentcilium

TOGARAM2 DRC7 EZR DYDC1 CCDC88A KIF27 RAB27A MROH2B

5.89e-04898458GO:0005929
GeneOntologyCellularComponentpresynaptic endocytic zone

DNAJC6 MYO6

6.78e-0418452GO:0098833
GeneOntologyCellularComponentmicrotubule organizing center

MYO18A SEPTIN1 EZR CCDC88A RAB11FIP4 SKA3 CEP112 SMTNL2

6.86e-04919458GO:0005815
GeneOntologyCellularComponentmyosin filament

MYO18A MYH13

1.32e-0325452GO:0032982
GeneOntologyCellularComponentmyosin II complex

MYO18A MYH13

1.65e-0328452GO:0016460
GeneOntologyCellularComponentmelanosome

CALU RAB27A SLC2A1

1.85e-03113453GO:0042470
GeneOntologyCellularComponentpigment granule

CALU RAB27A SLC2A1

1.85e-03113453GO:0048770
GeneOntologyCellularComponentpreribosome

RIOK1 RPS3A UTP14A

1.90e-03114453GO:0030684
GeneOntologyCellularComponentactomyosin

MYO18A SEPTIN11 SEPTIN5

2.04e-03117453GO:0042641
GeneOntologyCellularComponentribbon synapse

UNC13B MYO6

2.16e-0332452GO:0097470
GeneOntologyCellularComponentcortical cytoskeleton

EZR SLC2A1 MAEA

2.70e-03129453GO:0030863
GeneOntologyCellularComponentcalyx of Held

UNC13B SEPTIN5

2.72e-0336452GO:0044305
GeneOntologyCellularComponentfilamentous actin

MYO6 SMTNL2

3.03e-0338452GO:0031941
GeneOntologyCellularComponentactin filament

EZR MYO6 SMTNL2

3.82e-03146453GO:0005884
GeneOntologyCellularComponentplasma membrane raft

EZR HK1 SLC2A1

3.90e-03147453GO:0044853
GeneOntologyCellularComponentbrush border

MYO18A EZR MYO6

4.28e-03152453GO:0005903
GeneOntologyCellularComponentexocytic vesicle

UNC13B SEPTIN1 SEPTIN5 RAB27A

4.90e-03320454GO:0070382
GeneOntologyCellularComponenttransport vesicle

UNC13B SEPTIN1 CCDC88A SEPTIN5 RAB27A

4.99e-03519455GO:0030133
GeneOntologyCellularComponentneuron to neuron synapse

UNC13B SEPTIN11 ANK3 DNAJC6 MYO6

5.15e-03523455GO:0098984
DomainSeptin

SEPTIN1 SEPTIN11 SEPTIN5

3.43e-0613443PF00735
DomainG_SEPTIN_dom

SEPTIN1 SEPTIN11 SEPTIN5

3.43e-0613443IPR030379
DomainG_SEPTIN

SEPTIN1 SEPTIN11 SEPTIN5

3.43e-0613443PS51719
DomainSeptin

SEPTIN1 SEPTIN11 SEPTIN5

4.36e-0614443IPR016491
DomainFERM_CS

EZR PTPN3 PTPN14

2.39e-0524443IPR019747
DomainFERM_C

EZR PTPN3 PTPN14

3.05e-0526443PF09380
DomainFERM_C

EZR PTPN3 PTPN14

3.43e-0527443SM01196
DomainFERM_PH-like_C

EZR PTPN3 PTPN14

3.43e-0527443IPR018980
DomainFERM_N

EZR PTPN3 PTPN14

6.33e-0533443IPR018979
DomainFERM_N

EZR PTPN3 PTPN14

6.33e-0533443PF09379
DomainMYOSIN_MOTOR

MYO18A MYH13 MYO6

9.71e-0538443PS51456
DomainMyosin_head

MYO18A MYH13 MYO6

9.71e-0538443PF00063
DomainMyosin_head_motor_dom

MYO18A MYH13 MYO6

9.71e-0538443IPR001609
DomainMYSc

MYO18A MYH13 MYO6

9.71e-0538443SM00242
DomainP-loop_NTPase

MYO18A SEPTIN1 SEPTIN11 KIF27 MYH13 ATAD2 SEPTIN5 MYO6 RAB27A

1.33e-04848449IPR027417
DomainFERM_M

EZR PTPN3 PTPN14

1.73e-0446443PF00373
DomainFERM_central

EZR PTPN3 PTPN14

2.08e-0449443IPR019748
DomainFERM_domain

EZR PTPN3 PTPN14

2.08e-0449443IPR000299
Domain-

EZR PTPN3 PTPN14

2.08e-04494431.20.80.10
DomainFERM_1

EZR PTPN3 PTPN14

2.21e-0450443PS00660
DomainFERM_2

EZR PTPN3 PTPN14

2.21e-0450443PS00661
DomainBand_41_domain

EZR PTPN3 PTPN14

2.21e-0450443IPR019749
DomainB41

EZR PTPN3 PTPN14

2.21e-0450443SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

EZR PTPN3 PTPN14

2.21e-0450443IPR014352
DomainFERM_3

EZR PTPN3 PTPN14

2.21e-0450443PS50057
DomainIQ

MYO18A MYH13 MYO6

6.23e-0471443PF00612
DomainMyosin_tail_1

MYO18A MYH13

8.10e-0418442PF01576
DomainMyosin_tail

MYO18A MYH13

8.10e-0418442IPR002928
DomainMyosin-like_IQ_dom

MYO18A MYH13

9.04e-0419442IPR027401
Domain-

MYO18A MYH13

9.04e-04194424.10.270.10
DomainIQ

MYO18A MYH13 MYO6

9.16e-0481443SM00015
DomainTYR_PHOSPHATASE_1

PTPN3 PTPN14 DNAJC6

1.09e-0386443PS00383
DomainEz/rad/moesin-like

EZR PTPN3

1.11e-0321442IPR000798
DomainTYR_PHOSPHATASE_2

PTPN3 PTPN14 DNAJC6

1.13e-0387443PS50056
DomainTYR_PHOSPHATASE_dom

PTPN3 PTPN14 DNAJC6

1.13e-0387443IPR000387
DomainIQ_motif_EF-hand-BS

MYO18A MYH13 MYO6

1.24e-0390443IPR000048
Domain-

PTPN3 PTPN14 DNAJC6

1.32e-03924433.90.190.10
DomainIQ

MYO18A MYH13 MYO6

1.37e-0393443PS50096
DomainProt-tyrosine_phosphatase-like

PTPN3 PTPN14 DNAJC6

1.63e-0399443IPR029021
DomainPTPc

PTPN3 PTPN14

3.25e-0336442SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN3 PTPN14

3.80e-0339442PS50055
DomainPTPase_domain

PTPN3 PTPN14

4.20e-0341442IPR000242
DomainY_phosphatase

PTPN3 PTPN14

4.20e-0341442PF00102
Domain-

MYO18A SEPTIN1 SEPTIN11 ATAD2 SEPTIN5 RAB27A

7.70e-037464463.40.50.300
DomainPTPc_motif

PTPN3 PTPN14

8.52e-0359442SM00404
DomainTyr_Pase_cat

PTPN3 PTPN14

8.52e-0359442IPR003595
DomainUbiquitin-rel_dom

EZR PTPN3 PTPN14

9.26e-03184443IPR029071
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

EZR SEPTIN11 PTPN3 PTPN14 CCDC88A SASH1 ANK3 MYO6

2.69e-0837745838117590
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MYO18A PTPN14 CCDC88A HK1 ANK3 DNAJC6 MYO6 CALU RPS3A ST7 SLC2A1 GOLGB1 UTP14A

3.08e-081487451333957083
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

MYO18A SZT2 RPS3A CEP112 SLC2A1 GOLGB1

2.85e-0720845633230847
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

PTPN3 CCDC88A HK1 MYH13 ANK3 MYO6 RPS3A GOLGB1 UTP14A

5.71e-0777745935844135
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

EZR SEPTIN11 ZNF821 RHBDL2 ANK3 UBE2V1 CEP112 SLC2A1 GOLGB1 UTP14A

9.82e-071084451011544199
Pubmed

Localization of septin proteins in the mouse cochlea.

SEPTIN1 SEPTIN11 SEPTIN5

1.12e-061645322575789
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

EZR SEPTIN11 HK1 MYH13 MYO6 RPS3A SLC2A1 GOLGB1 MAEA

1.17e-0684745935235311
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

MYO18A SEPTIN11 HK1 SASH1 SEPTIN5 MYO6 RPS3A SLC2A1

1.19e-0662145822794259
Pubmed

Ezrin is down-regulated in diabetic kidney glomeruli and regulates actin reorganization and glucose uptake via GLUT1 in cultured podocytes.

EZR SLC2A1

4.91e-06345224726496
Pubmed

Septin expression in proliferative retinal membranes.

SEPTIN11 SEPTIN5

4.91e-06345217625225
Pubmed

Family-based association study between SLC2A1, HK1, and LEPR polymorphisms with myelomeningocele in Chile.

HK1 SLC2A1

4.91e-06345223427181
Pubmed

Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5.

SEPTIN11 SEPTIN5

4.91e-06345216767699
Pubmed

Tolbutamide alters glucose transport and metabolism in the embryonic mouse heart.

HK1 SLC2A1

4.91e-06345211835228
Pubmed

Genes in glucose metabolism and association with spina bifida.

HK1 SLC2A1

4.91e-06345218212354
Pubmed

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.

MYO18A EZR SEPTIN11 HK1 MYO6 RPS3A SLC2A1

6.57e-0655245736293380
Pubmed

Developmental regulation of genes mediating murine brain glucose uptake.

HK1 SLC2A1

9.81e-06445210070152
Pubmed

Main effects and interactions of carbonic anhydrase IX, hypoxia-inducible factor-1α, ezrin and glucose transporter-1 in multivariate analysis for disease outcome in rectal cancer.

EZR SLC2A1

9.81e-06445222843905
Pubmed

Carbonic anhydrase IX, hypoxia-inducible factor-1α, ezrin and glucose transporter-1 as predictors of disease outcome in rectal cancer: multivariate Cox survival models following data reduction by principal component analysis of the clinicopathological predictors.

EZR SLC2A1

9.81e-06445222199327
Pubmed

The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis.

UNC13B RAB27A

9.81e-06445214593078
Pubmed

Slp2-a controls renal epithelial cell size through regulation of Rap-ezrin signaling independently of Rab27.

EZR RAB27A

9.81e-06445224284068
Pubmed

High 18F-FDG uptake in PMAH correlated with normal expression of Glut1, HK1, HK2, and HK3.

HK1 SLC2A1

9.81e-06445225766729
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EZR RIOK1 HK1 KIF27 ATAD2 MYO6 CALU RPS3A SLC2A1 UTP14A

1.11e-051425451030948266
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PTPN3 PTPN14 CCDC88A SKA3 SASH1 CALU CEP112 GOLGB1

1.31e-0586145836931259
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

MYO18A EZR SEPTIN11 RIOK1 HK1 ANK3 MYO6 CALU RPS3A

1.38e-05114945935446349
Pubmed

Gene discovery in the hamster: a comparative genomics approach for gene annotation by sequencing of hamster testis cDNAs.

KIF27 MROH2B

1.63e-05545212783626
Pubmed

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation.

SEPTIN11 SEPTIN5

1.63e-05545224113571
Pubmed

Mutation of FAS, XIAP, and UNC13D genes in a patient with a complex lymphoproliferative phenotype.

UNC13B RAB27A

1.63e-05545224043286
Pubmed

Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a link between GLUT1 and the cytoskeleton.

MYO6 SLC2A1

1.63e-05545210198040
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

PTPN14 CCDC88A SASH1 ANK3 RAB27A GOLGB1

1.66e-0542145636976175
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SEPTIN11 ANK3 SEPTIN5 DNAJC6 UBE2V1

1.82e-0525145527507650
Pubmed

Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.

EZR SEPTIN11 BEX3 RIOK1 CALU RPS3A

1.92e-054324567671812
Pubmed

The nucleoplasmic phase of pre-40S formation prior to nuclear export.

RIOK1 RPS3A UTP14A

2.08e-054145336321656
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

PTPN14 CCDC88A ANK3 MYO6 GOLGB1

2.27e-0526345534702444
Pubmed

GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBP.

MYO6 SLC2A1

2.45e-05645215975910
Pubmed

CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI.

EZR MYO6

2.45e-05645224285636
Pubmed

The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation.

EZR MYO6

2.45e-0564529852149
Pubmed

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.

MYO18A EZR MYO6

2.76e-054545322114352
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MYO18A EZR LAMB3 PTPN3 PTPN14 MYO6 RPS3A SLC2A1 UTP14A

2.80e-05125745936526897
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

EZR SEPTIN11 CCDC88A ANK3 SEPTIN5 DNAJC6 UBE2V1 GOLGB1

2.92e-0596345828671696
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

EZR RIOK1 CCDC88A ANK3 MYO6 RPS3A GOLGB1

3.26e-0570845739231216
Pubmed

Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes.

MYO6 RAB27A

3.42e-05745215572405
Pubmed

A human MAP kinase interactome.

MYO18A PTPN3 CCDC88A ANK3 MYO6 GOLGB1

3.71e-0548645620936779
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

TOGARAM2 SEPTIN1 RIOK1 MYH13 ANK3 MYO6

4.20e-0549745636774506
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

HK1 KIF27 ANK3 SEPTIN5 UBE2V1

4.53e-0530445532235678
Pubmed

TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT-GSK-3β-β-Catenin Signaling Pathway.

MYO18A KIF27 MYH13 MYO6 RPS3A

4.60e-0530545533194618
Pubmed

Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma.

HK1 SLC2A1

5.86e-05945219554504
Pubmed

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.

SEPTIN11 SEPTIN5

5.86e-05945218809578
Pubmed

DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse.

SEPTIN11 SEPTIN5

7.32e-051045235200715
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYO18A SEPTIN11 HK1 ANK3 SEPTIN5 DNAJC6 MYO6 RPS3A SLC2A1

7.65e-05143145937142655
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

EZR ANK3 SEPTIN5 MYO6 RPS3A SLC2A1

7.95e-0555845635063084
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

L1TD1 PTPN14 HK1 UTP14A

8.21e-0517745426206133
Pubmed

Synaptic vesicle trafficking and Parkinson's disease.

SEPTIN5 RAB27A

8.94e-051145221563316
Pubmed

Functional proteomics mapping of a human signaling pathway.

L1TD1 SASH1 ANK3 MYO6 RPS3A GOLGB1

1.09e-0459145615231748
Pubmed

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

CALU RAB27A SLC2A1

1.49e-047945317081065
Pubmed

A protein interaction landscape of breast cancer.

MYO18A LAMB3 PTPN14 HK1 ANK3 MYO6

1.60e-0463445634591612
Pubmed

Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.

EZR ANK3

1.70e-041545230562487
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

SEPTIN11 HK1 ANK3 SEPTIN5 DNAJC6

1.70e-0440345530562941
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYO18A EZR LAMB3 MYH13 MYO6 CALU

1.78e-0464745626618866
Pubmed

Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling.

HK1 SLC2A1

1.94e-041645224697899
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B EZR BEX3 ZNF821 RIPK4 RAB11FIP4 ANK3 MYO6

2.17e-04128545835914814
Pubmed

Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression.

SEPTIN1 RIPK4

2.20e-041745212747765
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

UNC13B LAMB3 ANK3 ATAD2 DNAJC6 SLC2A1 GOLGB1 UTP14A

2.26e-04129345815342556
Pubmed

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

MYO18A ANK3 MYO6 RPS3A

2.36e-0423345429518331
Pubmed

Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse.

SRRM3 MYO6

2.47e-041845233087486
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

EZR SEPTIN11 RIOK1 PTPN14 CCDC88A ANK3 UBE2V1 MAEA

2.61e-04132145827173435
Pubmed

SASH1 is a scaffold molecule in endothelial TLR4 signaling.

SASH1 UBE2V1

2.76e-041945223776175
Pubmed

The aryl hydrocarbon receptor promotes differentiation during mouse preimplantational embryo development.

HK1 SLC2A1

2.76e-041945234478649
Pubmed

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.

SYCP2 HK1 MYO6

3.00e-0410045326073538
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

PTPN14 CCDC88A ANK3 ATAD2

3.13e-0425145429778605
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

MYO18A EZR SEPTIN11 HK1 SKA3 CALU SLC2A1 GOLGB1

3.29e-04136745832687490
Pubmed

Glucocorticoid receptor is required for foetal heart maturation.

HK1 SLC2A1

3.72e-042245223595884
Pubmed

Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.

RHBDL2 SLC2A1 SMTNL2

3.76e-0410845331202927
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

EZR HK1 RPS3A SLC2A1 GOLGB1

3.95e-0448445531995728
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

EZR SEPTIN11 MYO6 RPS3A GOLGB1

4.83e-0450645530890647
Pubmed

Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.

PTPN14 MAEA

5.22e-042645228720576
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

PTPN14 HK1 ANK3 RAB27A

5.25e-0428845438496616
Pubmed

LZTR1 is a regulator of RAS ubiquitination and signaling.

SEPTIN11 SEPTIN5 RAB27A

6.03e-0412745330442766
Pubmed

Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.

CALU RAB27A

6.50e-042945212643545
Pubmed

Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice.

MYO18A MYO6

6.96e-043045228077597
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

MYO18A HK1 MYO6 RPS3A

7.08e-0431245437120454
Pubmed

PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.

HK1 CALU SLC2A1

7.36e-0413645322304920
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

HK1 UBE2V1 CALU RPS3A GOLGB1

7.88e-0456445521565611
Pubmed

Cdx2 regulates endo-lysosomal function and epithelial cell polarity.

EZR MYO6

8.43e-043345220551175
Pubmed

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.

MYO18A RIOK1 MYO6 RPS3A

8.53e-0432845423398456
Pubmed

HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.

CEP112 GOLGB1

8.94e-043445225925205
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

MYO18A HK1 MYO6 UTP14A

9.13e-0433445430425250
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

SEPTIN11 CCDC88A MYO6

1.09e-0315645330409884
Pubmed

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.

HK1 SLC2A1

1.12e-033845220185832
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

EZR RIOK1 MYO6 CALU RAB27A

1.14e-0361345522268729
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RIOK1 SKA3 MYO6 RPS3A GOLGB1 UTP14A

1.23e-0393445633916271
Pubmed

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.

HK1 SLC2A1

1.24e-034045227760309
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

EZR LAMB3

1.24e-034045227068110
Pubmed

140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.

SEPTIN11 SEPTIN5 UBE2V1

1.24e-0316345316512683
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

MYO18A MYO6 CALU RPS3A SLC2A1

1.25e-0362645533644029
InteractionSEPTIN1 interactions

MYO18A SEPTIN1 SEPTIN11 RIPK4 SEPTIN5

5.65e-0846455int:SEPTIN1
InteractionKCNA3 interactions

MYO18A EZR RIOK1 CCDC88A ANK3 MYO6 SZT2 RPS3A CEP112 SLC2A1 GOLGB1

2.43e-068714511int:KCNA3
InteractionARF6 interactions

EZR SEPTIN11 PTPN14 CCDC88A RAB11FIP4 HK1 ANK3 MYO6 SLC2A1

4.73e-06584459int:ARF6
InteractionMCAM interactions

EZR SEPTIN11 PTPN3 PTPN14 CCDC88A SASH1 ANK3 MYO6

8.07e-06468458int:MCAM
InteractionRHOA interactions

MYO18A EZR RIPK4 PTPN14 CCDC88A HK1 ANK3 ATAD2 MYO6 ST7 SLC2A1 GOLGB1

8.56e-0611994512int:RHOA
InteractionSEPTIN10 interactions

SEPTIN1 SEPTIN11 CCDC88A SEPTIN5 GOLGB1

1.69e-05144455int:SEPTIN10
InteractionSFN interactions

PTPN3 PTPN14 CCDC88A SKA3 SASH1 UBE2V1 RPS3A CEP112 SMTNL2

1.84e-05692459int:SFN
InteractionDNAJC5 interactions

MYO18A PTPN14 CCDC88A ANK3 MYO6 SLC2A1 GOLGB1

1.90e-05378457int:DNAJC5
InteractionYWHAQ interactions

PTPN3 RIPK4 PTPN14 CCDC88A MYH13 SASH1 UBE2V1 CALU CEP112 GOLGB1 SMTNL2

2.59e-0511184511int:YWHAQ
InteractionSEPTIN12 interactions

SEPTIN1 SEPTIN11 SEPTIN5

2.61e-0526453int:SEPTIN12
InteractionRND3 interactions

MYO18A PTPN14 CCDC88A ANK3 MYO6 SLC2A1

3.06e-05273456int:RND3
InteractionSEPTIN8 interactions

SEPTIN1 EZR SEPTIN11 SEPTIN5

4.22e-0587454int:SEPTIN8
InteractionSEPTIN6 interactions

SEPTIN1 EZR SEPTIN11 SEPTIN5

4.41e-0588454int:SEPTIN6
InteractionVDAC2 interactions

EZR SEPTIN11 RIPK4 HK1 CALU RPS3A UTP14A

4.45e-05432457int:VDAC2
InteractionSLX9 interactions

EZR RIOK1 ATAD2 RPS3A UTP14A

4.54e-05177455int:SLX9
InteractionSEPTIN4 interactions

SEPTIN1 SEPTIN11 SEPTIN5

8.31e-0538453int:SEPTIN4
InteractionMYH13 interactions

EZR MYH13 DNAJC6

1.68e-0448453int:MYH13
InteractionHTT interactions

MYO18A SEPTIN11 HK1 SASH1 SEPTIN5 MYO6 RPS3A SLC2A1 UTP14A

2.10e-04949459int:HTT
Cytoband1p31.3

L1TD1 DNAJC6

1.16e-03514521p31.3
Cytoband1p34.2

SZT2 SLC2A1

1.45e-03574521p34.2
CytobandEnsembl 112 genes in cytogenetic band chr1p34

RHBDL2 SZT2 SLC2A1

3.02e-03294453chr1p34
GeneFamilySeptins

SEPTIN1 SEPTIN11 SEPTIN5

9.42e-0713283732
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

EZR PTPN3 PTPN14

6.21e-05502831293
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN3 PTPN14

3.48e-0418282812
GeneFamilyPDZ domain containing

MYO18A PTPN3

2.30e-021522821220
ToppCellASK452-Epithelial-Transformed_epithelium|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

EZR LAMB3 BEX3 ANK3 MYO6 GOLGB1

4.61e-08197456b22a79a5922c865a360e2afc5506a08a512fa76a
ToppCellASK452-Epithelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

EZR LAMB3 BEX3 ANK3 MYO6 GOLGB1

4.90e-08199456e8778d4d2bc7e15b4c7989a93e5808a76738df46
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

LAMB3 PTPN3 RIPK4 FMO2 ANK3

1.10e-06182455caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB3 PTPN3 RIPK4 FMO2 ANK3

1.22e-06186455e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

LAMB3 PTPN3 RIPK4 PTPN14 ANK3

1.26e-061874558407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

UNC13B ZNF821 SYCP2 ANK3 MYO6

1.32e-061894553717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellE15.5-Epithelial|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EZR LAMB3 BEX3 ANK3 RPS3A

1.43e-061924553f2ecd428c0c608d7bbd7b403a07399b87761338
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B EZR ANK3 ST7 RAB27A

1.50e-0619445597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

UNC13B LAMB3 PTPN3 ANK3 GOLGB1

1.62e-061974551a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B PTPN3 ANK3 MYO6 ST7

1.70e-061994555f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellBronchial_Biopsy-Epithelial|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

EZR LAMB3 FMO2 ANK3 GOLGB1

1.70e-06199455ef5d8917c8d011184830a0b8197afc6266707b37
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B SASH1 MYO6 CEP112 SLC2A1

1.75e-06200455032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B SASH1 MYO6 CEP112 SLC2A1

1.75e-0620045568fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B SASH1 MYO6 CEP112 SLC2A1

1.75e-06200455376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B SASH1 MYO6 CEP112 SLC2A1

1.75e-062004557fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B SASH1 MYO6 CEP112 SLC2A1

1.75e-06200455878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B SASH1 MYO6 CEP112 SLC2A1

1.75e-062004557136936d05ab344a560cf159684c881063b5430d
ToppCellASK440-Epithelial|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

EZR LAMB3 BEX3 FMO2 ANK3

1.75e-06200455cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB3 PTPN3 RIPK4 FMO2

1.72e-05153454e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCelldroplet-Fat-Scat-21m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN1 EZR MYH13 RPS3A

2.10e-05161454e52735f955f0a53da5cbe5a2d77a00484e5109b3
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN1 L1TD1 BEX3 RAB27A

2.15e-0516245416f9fbcaa0093ffc5a2a5e32db6040e2cb519d47
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN1 DRC7 L1TD1 SMTNL2

2.42e-05167454e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellControl|World / group, cell type (main and fine annotations)

UNC13B EZR ANK3 MYO6

2.48e-05168454a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

UNC13B PTPN14 ANK3 MYO6

2.60e-05170454e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

RHBDL2 RIPK4 ANK3 SLC2A1

2.66e-05171454adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellEpithelial-Epithelial-C_(AT2)|Epithelial / shred on cell class and cell subclass (v4)

BEX3 ANK3 RPS3A RAB27A

2.78e-05173454f57cbf5bd2a9e5db47b4919e9cd5e50781c1a990
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TOGARAM2 DRC7 DYDC1 KIF27

2.84e-05174454f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TOGARAM2 DRC7 DYDC1 KIF27

2.91e-05175454c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMB3 PTPN3 RIPK4 PTPN14

3.04e-05177454ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BEX3 ANK3 ATAD2 RAB27A

3.18e-05179454bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

LAMB3 RIPK4 PTPN14 ANK3

3.18e-05179454d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

LAMB3 BEX3 FMO2 PTPN14

3.25e-051804542d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOGARAM2 DRC7 DYDC1 DNAJC6

3.32e-05181454e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOGARAM2 DRC7 DYDC1 DNAJC6

3.32e-0518145411cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOGARAM2 DRC7 DYDC1 DNAJC6

3.32e-051814545ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

UNC13B EZR ANK3 MYO6

3.32e-05181454c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

LAMB3 PTPN3 FMO2 ANK3

3.39e-05182454759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

LAMB3 RIPK4 ANK3 RAB27A

3.46e-0518345423e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial-AT2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

LAMB3 RIPK4 ANK3 RAB27A

3.46e-051834540a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCelldroplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOGARAM2 DRC7 DYDC1 KIF27

3.46e-051834543991830726d05cf19606d540de04093985b7bdeb
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOGARAM2 DRC7 DYDC1 KIF27

3.46e-05183454cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCellImmune_cells-large_pre-B.|World / Lineage and Cell class

SEPTIN1 DRC7 EZR SMTNL2

3.46e-0518345481b5ed6ed661d2d6a9b807fefd2f0d59bd4ea77e
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR LAMB3 BEX3 RPS3A

3.54e-05184454e93633d89a9c54c8d2819f56372815b4ca149f06
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

UNC13B PTPN3 ANK3 MYO6

3.61e-05185454cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

UNC13B FMO2 ANK3 MYO6

3.69e-051864543006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB3 PTPN3 FMO2 ANK3

3.77e-05187454201ff693e4756ee3e44762885b3a303a77eb535b
ToppCelldroplet-Lung-LUNG-1m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOGARAM2 DRC7 KIF27 ANK3

3.77e-051874546288da8cdd450c58df00ebcfcc118f01fab7e610
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B LAMB3 PTPN14 MYO6

3.85e-05188454eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellLPS-IL1RA-Epithelial_alveolar|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB3 PTPN3 FMO2 ANK3

3.85e-051884546164d467b612767ceba15de34176bcc8e8c36ab8
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

UNC13B PTPN3 ANK3 MYO6

3.85e-05188454c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

UNC13B EZR ANK3 MYO6

3.85e-05188454707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCelldroplet-Lung-nan-18m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB3 RIPK4 MYH13 ANK3

3.93e-05189454ca657353f2b649530809c0bc057e448adc511ec1
ToppCelldroplet-Lung-1m-Epithelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOGARAM2 DRC7 KIF27 ANK3

3.93e-0518945472ecd5a10e419bac475e22f5b602e7f008835ce9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EZR LAMB3 PTPN3 PTPN14

3.93e-05189454aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B LAMB3 RIPK4 ANK3

3.93e-051894547659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCelldroplet-Lung-nan-18m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB3 RIPK4 MYH13 ANK3

3.93e-05189454e5325f1c7430b574947f8ee67e425455b60dc518
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EZR LAMB3 PTPN3 PTPN14

3.93e-051894548977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellICU-SEP-Lymphocyte-T_NK-CD4_TCM|ICU-SEP / Disease, Lineage and Cell Type

SEPTIN1 BEX3 ANK3 RPS3A

3.93e-051894549ed1cf4bb456780c1d1070de687bcabafd6287a3
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOGARAM2 DRC7 DYDC1 KIF27

4.01e-051904549ffd18ef358f8e32c610ab6420f479067c8ba44b
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

LAMB3 PTPN3 RIPK4 ANK3

4.01e-05190454ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR LAMB3 BEX3 RPS3A

4.01e-05190454422f58447e2b308f6f9dad822c4600c78e571c5d
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB3 RIPK4 MYH13 ANK3

4.01e-05190454a51405f8466fc6d4087873137472619b2e84c1da
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOGARAM2 DRC7 DYDC1 KIF27

4.01e-051904543ef39d61c98de4e5df946b995847aa65eba6a4b6
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYCP2 SKA3 CEP112 ST7

4.01e-05190454250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCelldroplet-Lung-nan-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOGARAM2 LAMB3 MYH13 ANK3

4.01e-05190454b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB3 RIPK4 MYH13 ANK3

4.01e-05190454059beca1c92181b8ba4dcd6fc71ff7530d83d0de
ToppCellE15.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EZR LAMB3 ANK3 RPS3A

4.09e-05191454402c341b00f98e8215458766b3c219fff8dcb447
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

EZR FMO2 PTPN14 ANK3

4.09e-0519145423776c7302cead3881b39127398f3b3e0d27885e
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB3 RIPK4 MYH13 ANK3

4.09e-05191454caed913e7ede9f8ae3af273d1ecf375de6c5e813
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B PTPN14 RAB27A SMTNL2

4.09e-051914544bfdf44d4402a42530d30c89d94946acdda4321b
ToppCelldroplet-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOGARAM2 LAMB3 MYH13 ANK3

4.09e-051914541b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR LAMB3 RIPK4 SLC2A1

4.18e-0519245418546b4d5e39aafa97186104d47cfda02eb5f4b5
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

LAMB3 PTPN3 RIPK4 ANK3

4.18e-051924549b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B PTPN3 ANK3 MYO6

4.18e-05192454fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellE15.5-Epithelial-alveolar_epithelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EZR LAMB3 ANK3 RPS3A

4.18e-05192454567f4355a01aae1f2eafc16fe86d1538a62030ab
ToppCellEpithelial|World / shred on cell class and cell subclass (v4)

EZR LAMB3 BEX3 ANK3

4.18e-0519245413a3553d9a7c78535679d23d454c63fd08f7d218
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B PTPN14 RAB27A SMTNL2

4.26e-05193454d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR LAMB3 RIPK4 ANK3

4.26e-05193454268925bfe85fb94a93a4ff8fe078d692df888140
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

EZR FMO2 PTPN14 ANK3

4.26e-051934542bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellE18.5-Epithelial-Epithelial_Alveolar|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR LAMB3 ANK3 RAB27A

4.26e-051934548e750a2b198ad6840a6842a7ddd93623faf7c656
ToppCellfacs-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOGARAM2 LAMB3 RIPK4 ANK3

4.26e-051934548e934f127bc763e905c788beabfa867bd559b682
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR LAMB3 ANK3 RAB27A

4.26e-051934546cc09f20dd119236c3c9968f3d16c3eabc0811e2
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SEPTIN1 BEX3 ANK3 RPS3A

4.35e-051944542e2019a7bf57f257f0ff9b24eacff59dbb952ebb
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR LAMB3 RIPK4 ANK3

4.35e-051944541531dcace28a14bd700e909a027426a8cee20337
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B PTPN14 RAB27A SMTNL2

4.35e-05194454c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EZR PTPN3 ANK3 MYO6

4.35e-051944547002937e8903e037332a215d00fbc7c7843b33f2
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SEPTIN1 BEX3 ANK3 RPS3A

4.35e-05194454d788d5bd1e651706e7e2d54ada546a5e84f86ff0
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEPTIN11 BEX3 ATAD2 UBE2V1

4.35e-05194454ded64ddab86de17fcf8b70d31bc26796eb71d60f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMB3 RIPK4 FMO2 MYO6

4.44e-05195454dd8117dbd22892288f74a7314ab0b5080106936c
ToppCellfacs-Tongue|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR LAMB3 RIPK4 SLC2A1

4.44e-0519545477128895db9221a64a171082d468ebcd6380c936
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMB3 RIPK4 FMO2 MYO6

4.44e-0519545482d87fdb39ec15be9057e2d2ba5c1afb5f97aafe
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR LAMB3 RPS3A SLC2A1

4.44e-05195454f7a4ce7076148389471678bcc5349df8b72b653e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 PTPN14 ANK3 MYO6

4.44e-051954546477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EZR FMO2 PTPN14 ANK3

4.44e-05195454dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCelldistal-Epithelial-Proximal_Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMB3 PTPN3 RIPK4 SRRM3

4.53e-05196454c102b28d5d1d90b9f7024cb51114276354be26a5
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EZR DNAJC6 SLC2A1 SMTNL2

4.53e-05196454429de4119c8b2193c992d36a6af84f806730cbee
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

UNC13B BEX3 ANK3 RAB27A

4.53e-05196454754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LAMB3 RIPK4 FMO2 PTPN14

4.53e-051964543b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCelldistal-Epithelial-Proximal_Basal-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMB3 PTPN3 RIPK4 SRRM3

4.53e-05196454a543d4623096cb3f9170dbf7af52381e77aa435e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EZR PTPN3 ANK3 MYO6

4.53e-051964546ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
DiseaseDegenerative polyarthritis

EZR MYH13 SLC2A1

3.66e-0493443C0029408
DiseaseOsteoarthrosis Deformans

EZR MYH13 SLC2A1

3.66e-0493443C0086743
Diseaseperipheral neuropathy, response to antimicrotubule agent

SEPTIN5 CALU

5.39e-0423442EFO_0003100, EFO_0005260
DiseaseAtaxia

HK1 SLC2A1

6.38e-0425442C0004134
Diseaseneuroblastoma

L1TD1 LAMB3 MYH13

6.97e-04116443EFO_0000621
DiseaseGlobal developmental delay

HK1 SZT2 SLC2A1

1.04e-03133443C0557874
Diseaseresponse to serotonin-norephinephrine reuptake inhibitor

ANK3 MAEA

1.33e-0336442EFO_0006325
DiseaseDevelopmental delay (disorder)

SZT2 SLC2A1

1.40e-0337442C0424605

Protein segments in the cluster

PeptideGeneStartEntry
DMEIFMEEMREIRRK

BEX3

66

Q00994
RIREKELDMKTKMME

CEP112

251

Q8N8E3
QMMVRDERRFKMADK

CALU

151

O43852
MKKMRRQRMRELEDL

ATAD2

191

Q6PL18
MLLDLIMKRMERCVD

RAB27A

176

P51159
MELMEKKLMDYIDQR

PAAT

386

Q9H8K7
LRLKDEMDLYKRMMD

RAB11FIP4

466

Q86YS3
LDIVRKMRDQRAMMV

PTPN3

871

P26045
KRKRMDRMMVEHLLR

MAEA

121

Q7L5Y9
RELALMEQEMMERLK

DYDC1

61

Q8WWB3
MEQEMMERLKAEELL

DYDC1

66

Q8WWB3
LQEMKEESRQMMREK

SLC2A1

241

P11166
LHDMEMERDMDRKKI

CCDC88A

391

Q3V6T2
MERDMDRKKIEELME

CCDC88A

396

Q3V6T2
EMKMKVLERDNMVRE

KIF27

1136

Q86VH2
QMLEQAKLRLEMEME

MYO18A

1566

Q92614
AKLRLEMEMERMRQT

MYO18A

1571

Q92614
MEDEMNEMKREGKFR

L1RE1

121

Q9UN81
KDMLLEVKKRMRAEM

HK1

481

P19367
RTIAEMRKEEMAKEM

DNAJC6

801

O75061
MRKEEMAKEMDPEKL

DNAJC6

806

O75061
ILKDVAEMKEDLMRM

ANK3

1901

Q12955
ARMEKMMRPVEVRKE

DRC7

26

Q8IY82
SERTMMMDIIKRNEK

FMO2

401

Q99518
EMMDRMKDMELELLR

LAMB3

1121

Q13751
EKEQMMREKEELMLR

EZR

336

P15311
ERDMDIIMKLKEEDM

RIOK1

441

Q9BRS2
KMAERRELERQMKME

SZT2

2801

Q5T011
RRVELKCMELQEMME

SRRM3

61

A6NNA2
MGREMKEELEEEEKM

RHBDL2

16

Q9NX52
RMKDEELRRMQEMLQ

SEPTIN5

346

Q99719
MRQMFVMRVKEKEAE

SEPTIN11

341

Q9NVA2
MQLKQMKEMELLRRL

TOGARAM2

361

Q6ZUX3
VRQIRKKMMEIMTRE

RPS3A

161

P61247
IEREMMIRNLEKQKM

PTPN14

841

Q15678
RTREAVKMMRDLMKE

ST7

311

Q9NRC1
KDMRDNNMLREIRML

MROH2B

61

Q7Z745
RERMELLEEAKKMEM

RIPK4

61

P57078
KDEELRRMQEMLEKM

SEPTIN1

341

Q8WYJ6
VLMEKNSMDIMKIRE

SKA3

81

Q8IX90
EMCLMKEDMKVLQDR

SYCP2

1486

Q9BX26
LQELRRLMMSKENMK

UBE2V1

121

Q13404
MRVEFKKMMERRDSI

MYH13

801

Q9UKX3
ERLIEVEDMMVMGRK

SMTNL2

426

Q2TAL5
DEERIQLMMMVKEKM

SASH1

186

O94885
NIIMAMKDRMKIRER

UNC13B

546

O14795
EELEKIEKARMMERM

UTP14A

281

Q9BVJ6
RLKRRLEKMDMMLRA

ZNF821

351

O75541
EAEQEMEEMKEKMRK

GOLGB1

1666

Q14789
KVLMEIQDLMFEEMR

L1TD1

56

Q5T7N2
EEERRMKLEMEAKRK

MYO6

951

Q9UM54