Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	NSD1 KMT2D NSD2 NSD3	2.96e-07	44	26	4	GO:0140938
GeneOntologyMolecularFunction	histone H3K36 methyltransferase activity	NSD1 NSD2 NSD3	5.56e-07	13	26	3	GO:0046975
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	NSD1 KMT2D NSD2 NSD3	1.74e-06	68	26	4	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	NSD1 KMT2D NSD2 NSD3	1.84e-06	69	26	4	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	NSD1 KMT2D NSD2 NSD3	2.07e-06	71	26	4	GO:0042054
GeneOntologyMolecularFunction	protein methyltransferase activity	NSD1 KMT2D NSD2 NSD3	9.15e-06	103	26	4	GO:0008276
GeneOntologyMolecularFunction	histone H3K36 dimethyltransferase activity	NSD1 NSD2	9.77e-06	4	26	2	GO:0140954
GeneOntologyMolecularFunction	N-methyltransferase activity	NSD1 KMT2D NSD2 NSD3	9.87e-06	105	26	4	GO:0008170
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme binding	ANKIB1 ARIH1 ARIH2	1.36e-05	36	26	3	GO:0031624
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme binding	ANKIB1 ARIH1 ARIH2	2.18e-05	42	26	3	GO:0044390
GeneOntologyMolecularFunction	S-adenosylmethionine-dependent methyltransferase activity	NSD1 KMT2D NSD2 NSD3	6.85e-05	172	26	4	GO:0008757
GeneOntologyMolecularFunction	histone H4K20 methyltransferase activity	NSD1 NSD2	7.29e-05	10	26	2	GO:0042799
GeneOntologyMolecularFunction	methyltransferase activity	NSD1 KMT2D NSD2 NSD3	1.57e-04	213	26	4	GO:0008168
GeneOntologyMolecularFunction	cargo receptor activity	LRP1 LRP2 FOLR2	1.80e-04	85	26	3	GO:0038024
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	NSD1 KMT2D NSD2 NSD3	1.90e-04	224	26	4	GO:0016741
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1 LRP2	1.93e-04	16	26	2	GO:0005041
GeneOntologyMolecularFunction	histone modifying activity	NSD1 KMT2D NSD2 NSD3	2.07e-04	229	26	4	GO:0140993
GeneOntologyMolecularFunction	histone H4 methyltransferase activity	NSD1 NSD2	2.19e-04	17	26	2	GO:0140939
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2D NSD3	3.05e-04	20	26	2	GO:0042800
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1 LRP2	3.37e-04	21	26	2	GO:0030228
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN2A SCN4A	5.20e-04	26	26	2	GO:0005248
GeneOntologyMolecularFunction	zinc ion binding	ANKIB1 NSD1 CHD3 ARIH1 DMD ARIH2	8.29e-04	891	26	6	GO:0008270
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD3 CHD5	1.06e-03	37	26	2	GO:0140658
GeneOntologyMolecularFunction	lipoprotein particle receptor binding	LRP1 LRP2	1.17e-03	39	26	2	GO:0070325
GeneOntologyMolecularFunction	integrin binding	CCN4 ITGBL1 DMD	1.48e-03	175	26	3	GO:0005178
GeneOntologyMolecularFunction	sodium channel activity	SCN2A SCN4A	2.08e-03	52	26	2	GO:0005272
GeneOntologyMolecularFunction	transition metal ion binding	ANKIB1 NSD1 CHD3 ARIH1 DMD ARIH2	3.62e-03	1189	26	6	GO:0046914
GeneOntologyMolecularFunction	sulfur compound binding	LRP1 CCN4 PLA2G5	8.28e-03	323	26	3	GO:1901681
GeneOntologyBiologicalProcess	chemoattraction of axon	LRP1 LRP2	1.52e-05	5	26	2	GO:0061642
GeneOntologyBiologicalProcess	positive regulation of lysosomal protein catabolic process	LRP1 LRP2	1.52e-05	5	26	2	GO:1905167
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process in the vacuole	LRP1 LRP2	3.20e-05	7	26	2	GO:1904352
GeneOntologyBiologicalProcess	folic acid transport	LRP2 FOLR2	8.35e-05	11	26	2	GO:0015884
GeneOntologyBiologicalProcess	regulation of lysosomal protein catabolic process	LRP1 LRP2	1.00e-04	12	26	2	GO:1905165
GeneOntologyBiologicalProcess	regulation of protein catabolic process in the vacuole	LRP1 LRP2	1.38e-04	14	26	2	GO:1904350
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	DMD SCN2A SCN4A	1.76e-04	87	26	3	GO:0086001
GeneOntologyBiologicalProcess	gliogenesis	LRP1 LRP2 LAMA2 PTPRA DMD	1.86e-04	435	26	5	GO:0042063
GeneOntologyBiologicalProcess	methylation	NSD1 KMT2D NSD2 NSD3	1.98e-04	234	26	4	GO:0032259
GeneOntologyBiologicalProcess	chromatin remodeling	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	2.62e-04	741	26	6	GO:0006338
GeneOntologyBiologicalProcess	regulation of skeletal muscle contraction	DMD SCN4A	2.86e-04	20	26	2	GO:0014819
GeneOntologyBiologicalProcess	cell-matrix adhesion	LRP1 ITGBL1 PTPRA DMD	3.42e-04	270	26	4	GO:0007160
GeneOntologyBiologicalProcess	regulation of phospholipase activity	LRP1 PLA2G5	3.48e-04	22	26	2	GO:0010517
GeneOntologyBiologicalProcess	positive regulation of cell differentiation	LRP1 LRP2 LAMA2 CCN4 PLA2G5 PTPRA DMD	4.04e-04	1141	26	7	GO:0045597
GeneOntologyBiologicalProcess	lysosomal protein catabolic process	LRP1 LRP2	4.15e-04	24	26	2	GO:1905146
GeneOntologyBiologicalProcess	transcytosis	LRP1 LRP2	4.15e-04	24	26	2	GO:0045056
GeneOntologyBiologicalProcess	integrin-mediated signaling pathway	LAMA2 ITGBL1 PTPRA	4.98e-04	124	26	3	GO:0007229
GeneOntologyBiologicalProcess	developmental cell growth	LRP1 CCN4 KMT2D ARIH2	5.16e-04	301	26	4	GO:0048588
GeneOntologyBiologicalProcess	central nervous system development	LRP1 LRP2 STK36 PTPRA DMD CHD5 SCN2A	5.40e-04	1197	26	7	GO:0007417
GeneOntologyBiologicalProcess	lipoprotein transport	LRP1 LRP2	5.66e-04	28	26	2	GO:0042953
GeneOntologyBiologicalProcess	protein catabolic process in the vacuole	LRP1 LRP2	5.66e-04	28	26	2	GO:0007039
GeneOntologyBiologicalProcess	lipoprotein localization	LRP1 LRP2	6.07e-04	29	26	2	GO:0044872
GeneOntologyBiologicalProcess	cardiac septum development	LRP1 LRP2 NSD2	6.25e-04	134	26	3	GO:0003279
GeneOntologyBiologicalProcess	glial cell differentiation	LRP1 LAMA2 PTPRA DMD	6.57e-04	321	26	4	GO:0010001
GeneOntologyBiologicalProcess	chromatin organization	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	7.20e-04	896	26	6	GO:0006325
GeneOntologyBiologicalProcess	regulation of cell-matrix adhesion	LRP1 PTPRA DMD	7.25e-04	141	26	3	GO:0001952
GeneOntologyBiologicalProcess	membrane depolarization during action potential	SCN2A SCN4A	9.38e-04	36	26	2	GO:0086010
GeneOntologyBiologicalProcess	amyloid-beta clearance	LRP1 LRP2	1.16e-03	40	26	2	GO:0097242
GeneOntologyBiologicalProcess	cardiac muscle contraction	DMD SCN2A SCN4A	1.18e-03	167	26	3	GO:0060048
GeneOntologyBiologicalProcess	regulation of lipase activity	LRP1 PLA2G5	1.22e-03	41	26	2	GO:0060191
GeneOntologyBiologicalProcess	protein-DNA complex organization	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	1.27e-03	999	26	6	GO:0071824
GeneOntologyBiologicalProcess	maintenance of blood-brain barrier	LAMA2 DMD	1.28e-03	42	26	2	GO:0035633
GeneOntologyBiologicalProcess	modified amino acid transport	LRP2 FOLR2	1.40e-03	44	26	2	GO:0072337
GeneOntologyBiologicalProcess	synaptic transmission, cholinergic	LAMA2 DMD	1.40e-03	44	26	2	GO:0007271
GeneOntologyBiologicalProcess	cell-substrate adhesion	LRP1 ITGBL1 PTPRA DMD	1.63e-03	410	26	4	GO:0031589
GeneOntologyBiologicalProcess	skeletal muscle contraction	DMD SCN4A	1.95e-03	52	26	2	GO:0003009
GeneOntologyBiologicalProcess	circulatory system process	LRP1 LRP2 DMD SCN2A SCN4A	1.98e-03	733	26	5	GO:0003013
GeneOntologyBiologicalProcess	action potential	DMD SCN2A SCN4A	2.01e-03	201	26	3	GO:0001508
GeneOntologyBiologicalProcess	determination of adult lifespan	DMD SCN2A	2.10e-03	54	26	2	GO:0008340
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	DMD SCN2A SCN4A	2.21e-03	208	26	3	GO:0035725
GeneOntologyBiologicalProcess	vitamin transport	LRP2 FOLR2	2.26e-03	56	26	2	GO:0051180
GeneOntologyBiologicalProcess	cardiac chamber development	LRP1 LRP2 NSD2	2.34e-03	212	26	3	GO:0003205
GeneOntologyBiologicalProcess	positive regulation of endocytosis	LRP1 LRP2 PLA2G5	2.37e-03	213	26	3	GO:0045807
GeneOntologyBiologicalProcess	striated muscle contraction	DMD SCN2A SCN4A	2.50e-03	217	26	3	GO:0006941
GeneOntologyCellularComponent	NuRD complex	CHD3 CHD5	2.00e-04	17	26	2	GO:0016581
GeneOntologyCellularComponent	CHD-type complex	CHD3 CHD5	2.00e-04	17	26	2	GO:0090545
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN2A SCN4A	2.00e-04	17	26	2	GO:0001518
GeneOntologyCellularComponent	sodium channel complex	SCN2A SCN4A	5.92e-04	29	26	2	GO:0034706
GeneOntologyCellularComponent	transferase complex	ANKIB1 NSD1 KMT2D UGT3A2 ARIH1 ARIH2	9.80e-04	963	26	6	GO:1990234
GeneOntologyCellularComponent	axonal growth cone	LRP1 LRP2	1.43e-03	45	26	2	GO:0044295
GeneOntologyCellularComponent	sarcolemma	LAMA2 DMD SCN2A	1.65e-03	190	26	3	GO:0042383
GeneOntologyCellularComponent	cell surface	LRP1 LRP2 PLA2G5 ITGBL1 DMD FOLR2	2.04e-03	1111	26	6	GO:0009986
GeneOntologyCellularComponent	cell-substrate junction	LRP1 ITGBL1 PTPRA DMD	2.06e-03	443	26	4	GO:0030055
GeneOntologyCellularComponent	protein complex involved in cell adhesion	LAMA2 ITGBL1	2.44e-03	59	26	2	GO:0098636
GeneOntologyCellularComponent	plasma membrane protein complex	LRP1 ITGBL1 DMD SCN2A SCN4A	2.51e-03	785	26	5	GO:0098797
MousePheno	increased variability of skeletal muscle fiber size	LAMA2 DMD SCN4A	5.25e-05	43	24	3	MP:0009403
MousePheno	abnormal circulating alkaline phosphatase level	LRP1 ANKIB1 PLA2G5 DMD TAFA4 NSD3 SCN4A	7.06e-05	639	24	7	MP:0000202
MousePheno	skeletal muscle endomysial fibrosis	LAMA2 DMD	1.01e-04	9	24	2	MP:0009420
MousePheno	myopathy	LAMA2 DMD SCN4A	1.04e-04	54	24	3	MP:0000751
MousePheno	limb grasping	ANKIB1 LAMA2 KMT2D GNL1 SCN4A	1.95e-04	325	24	5	MP:0001513
MousePheno	increased circulating alkaline phosphatase level	LRP1 ANKIB1 PLA2G5 DMD TAFA4 NSD3	2.08e-04	526	24	6	MP:0002968
MousePheno	abnormal sarcolemma morphology	LAMA2 DMD	2.93e-04	15	24	2	MP:0004121
MousePheno	increased muscle fatigability	DMD SCN4A	3.34e-04	16	24	2	MP:0003646
MousePheno	centrally nucleated skeletal muscle fibers	LAMA2 DMD SCN4A	3.35e-04	80	24	3	MP:0009404
MousePheno	skeletal muscle fiber necrosis	LAMA2 DMD	3.78e-04	17	24	2	MP:0009414
MousePheno	abnormal motor coordination/balance	LRP2 LAMA2 CCN4 STK36 KMT2D DMD SCN4A	4.89e-04	873	24	7	MP:0001516
MousePheno	abnormal sensory capabilities/reflexes/nociception	ANKIB1 LAMA2 PLA2G5 KMT2D PTPRA TAFA4 GNL1 NSD3 SCN4A	5.01e-04	1486	24	9	MP:0002067
MousePheno	decreased skeletal muscle fiber number	LAMA2 DMD	5.82e-04	21	24	2	MP:0009406
MousePheno	muscle weakness	LAMA2 DMD SCN4A	6.08e-04	98	24	3	MP:0000747
MousePheno	myositis	LAMA2 DMD	6.39e-04	22	24	2	MP:0004510
Domain	RING	ANKIB1 NSD1 CHD3 KMT2D ARIH1 NSD2 CHD5 NSD3 ARIH2	1.80e-10	305	26	9	SM00184
Domain	Znf_RING	ANKIB1 NSD1 CHD3 KMT2D ARIH1 NSD2 CHD5 NSD3 ARIH2	3.24e-10	326	26	9	IPR001841
Domain	PHD	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	7.39e-10	75	26	6	PF00628
Domain	Znf_FYVE_PHD	ANKIB1 NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	9.41e-10	147	26	7	IPR011011
Domain	Znf_PHD-finger	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	1.02e-09	79	26	6	IPR019787
Domain	PHD	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	2.10e-09	89	26	6	SM00249
Domain	Znf_PHD	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	2.41e-09	91	26	6	IPR001965
Domain	ZF_PHD_2	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	3.13e-09	95	26	6	PS50016
Domain	ZF_PHD_1	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	3.34e-09	96	26	6	PS01359
Domain	Post-SET_dom	NSD1 KMT2D NSD2 NSD3	5.31e-09	16	26	4	IPR003616
Domain	PostSET	NSD1 KMT2D NSD2 NSD3	5.31e-09	16	26	4	SM00508
Domain	POST_SET	NSD1 KMT2D NSD2 NSD3	5.31e-09	16	26	4	PS50868
Domain	-	ANKIB1 NSD1 CHD3 KMT2D ARIH1 NSD2 CHD5 NSD3 ARIH2	5.38e-09	449	26	9	3.30.40.10
Domain	Znf_RING/FYVE/PHD	ANKIB1 NSD1 CHD3 KMT2D ARIH1 NSD2 CHD5 NSD3 ARIH2	6.52e-09	459	26	9	IPR013083
Domain	AWS	NSD1 NSD2 NSD3	2.39e-08	5	26	3	PS51215
Domain	AWS_dom	NSD1 NSD2 NSD3	2.39e-08	5	26	3	IPR006560
Domain	AWS	NSD1 NSD2 NSD3	2.39e-08	5	26	3	SM00570
Domain	Zinc_finger_PHD-type_CS	NSD1 CHD3 NSD2 CHD5 NSD3	2.71e-08	65	26	5	IPR019786
Domain	E3_UB_ligase_RBR	ANKIB1 ARIH1 ARIH2	2.86e-07	10	26	3	IPR031127
Domain	SET	NSD1 KMT2D NSD2 NSD3	2.88e-07	41	26	4	PF00856
Domain	SET	NSD1 KMT2D NSD2 NSD3	4.63e-07	46	26	4	SM00317
Domain	SET_dom	NSD1 KMT2D NSD2 NSD3	6.50e-07	50	26	4	IPR001214
Domain	SET	NSD1 KMT2D NSD2 NSD3	6.50e-07	50	26	4	PS50280
Domain	IBR	ANKIB1 ARIH1 ARIH2	8.63e-07	14	26	3	PF01485
Domain	IBR	ANKIB1 ARIH1 ARIH2	8.63e-07	14	26	3	SM00647
Domain	-	CHD3 KMT2D NSD2 CHD5	9.59e-07	55	26	4	1.10.30.10
Domain	IBR_dom	ANKIB1 ARIH1 ARIH2	1.08e-06	15	26	3	IPR002867
Domain	HMG_box_dom	CHD3 KMT2D NSD2 CHD5	1.89e-06	65	26	4	IPR009071
Domain	PWWP	NSD1 NSD2 NSD3	2.69e-06	20	26	3	SM00293
Domain	PWWP	NSD1 NSD2 NSD3	4.16e-06	23	26	3	PF00855
Domain	PWWP_dom	NSD1 NSD2 NSD3	4.16e-06	23	26	3	IPR000313
Domain	PWWP	NSD1 NSD2 NSD3	4.75e-06	24	26	3	PS50812
Domain	CHDCT2	CHD3 CHD5	5.59e-06	3	26	2	PF08074
Domain	CHDNT	CHD3 CHD5	5.59e-06	3	26	2	PF08073
Domain	DUF1086	CHD3 CHD5	5.59e-06	3	26	2	IPR009462
Domain	DUF1087	CHD3 CHD5	5.59e-06	3	26	2	IPR009463
Domain	DUF1087	CHD3 CHD5	5.59e-06	3	26	2	PF06465
Domain	DUF1086	CHD3 CHD5	5.59e-06	3	26	2	PF06461
Domain	DUF1087	CHD3 CHD5	5.59e-06	3	26	2	SM01147
Domain	DUF1086	CHD3 CHD5	5.59e-06	3	26	2	SM01146
Domain	CHD_N	CHD3 CHD5	5.59e-06	3	26	2	IPR012958
Domain	CHD_C2	CHD3 CHD5	5.59e-06	3	26	2	IPR012957
Domain	TAFA	TAFA4 TAFA2	1.86e-05	5	26	2	PF12020
Domain	Chemokine-like_2FAM19A2	TAFA4 TAFA2	1.86e-05	5	26	2	PD298472
Domain	Chemokine-like_FAM19A2	TAFA4 TAFA2	1.86e-05	5	26	2	IPR020350
Domain	Na_channel_asu	SCN2A SCN4A	8.33e-05	10	26	2	IPR001696
Domain	Na_trans_assoc	SCN2A SCN4A	8.33e-05	10	26	2	IPR010526
Domain	Na_trans_assoc	SCN2A SCN4A	8.33e-05	10	26	2	PF06512
Domain	Ldl_recept_b	LRP1 LRP2	1.68e-04	14	26	2	PF00058
Domain	LDLRB	LRP1 LRP2	1.68e-04	14	26	2	PS51120
Domain	LY	LRP1 LRP2	1.93e-04	15	26	2	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP2	1.93e-04	15	26	2	IPR000033
Domain	EGF	LRP1 LRP2 LAMA2 ITGBL1	2.94e-04	235	26	4	SM00181
Domain	EGF-like_dom	LRP1 LRP2 LAMA2 ITGBL1	3.66e-04	249	26	4	IPR000742
Domain	EGF_1	LRP1 LRP2 LAMA2 ITGBL1	4.00e-04	255	26	4	PS00022
Domain	EGF_2	LRP1 LRP2 LAMA2 ITGBL1	4.63e-04	265	26	4	PS01186
Domain	Chromo_domain	CHD3 CHD5	5.05e-04	24	26	2	IPR023780
Domain	cEGF	LRP1 LRP2	5.93e-04	26	26	2	IPR026823
Domain	Chromo	CHD3 CHD5	5.93e-04	26	26	2	PF00385
Domain	cEGF	LRP1 LRP2	5.93e-04	26	26	2	PF12662
Domain	ZF_RING_1	ANKIB1 KMT2D ARIH1 ARIH2	6.58e-04	291	26	4	PS00518
Domain	CHROMO_2	CHD3 CHD5	6.89e-04	28	26	2	PS50013
Domain	CHROMO_1	CHD3 CHD5	6.89e-04	28	26	2	PS00598
Domain	ZF_RING_2	ANKIB1 KMT2D ARIH1 ARIH2	7.20e-04	298	26	4	PS50089
Domain	SNF2_N	CHD3 CHD5	9.01e-04	32	26	2	PF00176
Domain	SNF2_N	CHD3 CHD5	9.01e-04	32	26	2	IPR000330
Domain	Chromodomain-like	CHD3 CHD5	9.01e-04	32	26	2	IPR016197
Domain	CHROMO	CHD3 CHD5	9.58e-04	33	26	2	SM00298
Domain	Chromo/shadow_dom	CHD3 CHD5	9.58e-04	33	26	2	IPR000953
Domain	DNA/RNA_helicase_DEAH_CS	CHD3 CHD5	1.08e-03	35	26	2	IPR002464
Domain	DEAH_ATP_HELICASE	CHD3 CHD5	1.27e-03	38	26	2	PS00690
Domain	Growth_fac_rcpt_	LRP1 LRP2 CCN4	1.29e-03	156	26	3	IPR009030
Domain	-	LRP1 LRP2	1.34e-03	39	26	2	2.120.10.30
Domain	LDLR_class-A_CS	LRP1 LRP2	1.41e-03	40	26	2	IPR023415
Domain	Ldl_recept_a	LRP1 LRP2	1.78e-03	45	26	2	PF00057
Domain	-	LRP1 LRP2	1.86e-03	46	26	2	4.10.400.10
Domain	6-blade_b-propeller_TolB-like	LRP1 LRP2	1.86e-03	46	26	2	IPR011042
Domain	LDLRA_1	LRP1 LRP2	2.02e-03	48	26	2	PS01209
Domain	LDrepeatLR_classA_rpt	LRP1 LRP2	2.11e-03	49	26	2	IPR002172
Domain	LDLa	LRP1 LRP2	2.11e-03	49	26	2	SM00192
Domain	LDLRA_2	LRP1 LRP2	2.11e-03	49	26	2	PS50068
Domain	HMG_box	KMT2D NSD2	2.46e-03	53	26	2	PF00505
Domain	HMG	KMT2D NSD2	2.55e-03	54	26	2	SM00398
Domain	Channel_four-helix_dom	SCN2A SCN4A	2.84e-03	57	26	2	IPR027359
Domain	-	SCN2A SCN4A	2.84e-03	57	26	2	1.20.120.350
Domain	EGF_extracell	LRP2 ITGBL1	3.14e-03	60	26	2	IPR013111
Domain	EGF_2	LRP2 ITGBL1	3.14e-03	60	26	2	PF07974
Pathway	REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES	NSD1 KMT2D NSD2 NSD3	5.70e-07	46	21	4	MM14933
Pathway	REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES	NSD1 KMT2D NSD2 NSD3	3.13e-06	70	21	4	M27231
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	NSD1 CHD3 KMT2D NSD2 NSD3	4.82e-06	175	21	5	MM14941
Pathway	KEGG_LYSINE_DEGRADATION	NSD1 NSD2 NSD3	3.63e-05	44	21	3	M13720
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	NSD1 CHD3 KMT2D NSD2 NSD3	4.07e-05	272	21	5	M29619
Pathway	BIOCARTA_AGR_PATHWAY	LAMA2 DMD	9.58e-04	31	21	2	MM1343
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN2A SCN4A	9.58e-04	31	21	2	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN2A SCN4A	1.02e-03	32	21	2	M27455
Pathway	BIOCARTA_AGR_PATHWAY	LAMA2 DMD	1.09e-03	33	21	2	M6220
Pubmed	The NSD family of protein methyltransferases in human cancer.	NSD1 NSD2 NSD3	3.71e-10	3	26	3	25942451
Pubmed	The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors.	NSD1 NSD2 NSD3	3.71e-10	3	26	3	35532818
Pubmed	Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.	NSD1 NSD2 NSD3	1.48e-09	4	26	3	34271259
Pubmed	In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L.	NSD1 NSD2 NSD3	3.70e-09	5	26	3	25494638
Pubmed	Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation.	NSD1 NSD2 NSD3	3.70e-09	5	26	3	39390582
Pubmed	A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.	NSD1 NSD2 NSD3	1.34e-07	14	26	3	26912663
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	LRP1 LRP2 LAMA2 DMD	2.30e-07	71	26	4	33541421
Pubmed	Extended tropism of an adenoviral vector does not circumvent the maturation-dependent transducibility of mouse skeletal muscle.	LAMA2 DMD	5.37e-07	2	26	2	10753064
Pubmed	Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.	LRP1 LRP2	5.37e-07	2	26	2	34445520
Pubmed	Laminin-alpha2 but not -alpha1-mediated adhesion of human (Duchenne) and murine (mdx) dystrophic myotubes is seriously defective.	LAMA2 DMD	5.37e-07	2	26	2	9188790
Pubmed	Diseased muscles that lack dystrophin or laminin-alpha2 have altered compositions and proliferation of mononuclear cell populations.	LAMA2 DMD	5.37e-07	2	26	2	15817132
Pubmed	Muscular dystrophies: diseases of the dystrophin-glycoprotein complex.	LAMA2 DMD	5.37e-07	2	26	2	7481760
Pubmed	NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis.	NSD1 NSD2	5.37e-07	2	26	2	29176703
Pubmed	Analysis of dystrophin in fast- and slow-twitch skeletal muscles from mdx and dy2J mice at different ages.	LAMA2 DMD	5.37e-07	2	26	2	2183046
Pubmed	Muscle fiber growth and necrosis in dystrophic muscles: a comparative study between dy and mdx mice.	LAMA2 DMD	5.37e-07	2	26	2	3440862
Pubmed	Voltage-gated sodium channel (SkM1) content in dystrophin-deficient muscle.	DMD SCN4A	5.37e-07	2	26	2	11316257
Pubmed	Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle.	LAMA2 DMD	5.37e-07	2	26	2	16565216
Pubmed	Targeting H3K36 methyltransferases NSDs: a promising strategy for tumor targeted therapy.	NSD2 NSD3	5.37e-07	2	26	2	34083510
Pubmed	Quantitative morphology of mast cells in skeletal muscle of normal and genetically dystrophic mice.	LAMA2 DMD	5.37e-07	2	26	2	9066911
Pubmed	Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.	LAMA2 DMD	5.37e-07	2	26	2	9334342
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	LRP1 LRP2 NSD1 PTPRA ARIH1 NSD3 ARIH2	8.10e-07	730	26	7	34857952
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	LRP1 LRP2 LAMA2 DMD	1.11e-06	105	26	4	30280653
Pubmed	Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin.	LAMA2 DMD	1.61e-06	3	26	2	16684813
Pubmed	Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.	NSD2 NSD3	1.61e-06	3	26	2	33361816
Pubmed	Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity.	NSD2 NSD3	1.61e-06	3	26	2	16682010
Pubmed	Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.	LAMA2 DMD	1.61e-06	3	26	2	1757468
Pubmed	The histone methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1-mediated transcriptional repression.	NSD2 NSD3	1.61e-06	3	26	2	17239852
Pubmed	Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1.	DMD SCN4A	1.61e-06	3	26	2	17135300
Pubmed	Lysine methyltransferase 2D regulates muscle fiber size and muscle cell differentiation.	KMT2D DMD	1.61e-06	3	26	2	34613626
Pubmed	The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.	CHD3 KMT2D	1.61e-06	3	26	2	26551667
Pubmed	Proinflammatory signals and the loss of lymphatic vessel hyaluronan receptor-1 (LYVE-1) in the early pathogenesis of laminin alpha2-deficient skeletal muscle.	LAMA2 DMD	1.61e-06	3	26	2	20876525
Pubmed	Dystroglycan is not required for localization of dystrophin, syntrophin, and neuronal nitric-oxide synthase at the sarcolemma but regulates integrin alpha 7B expression and caveolin-3 distribution.	LAMA2 DMD	1.61e-06	3	26	2	11741881
Pubmed	The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.	NSD2 NSD3	1.61e-06	3	26	2	23269674
Pubmed	Tissue distribution of the dystrophin-related gene product and expression in the mdx and dy mouse.	LAMA2 DMD	1.61e-06	3	26	2	2014247
Pubmed	Spontaneous opening of the acetylcholine receptor channel in developing muscle cells from normal and dystrophic mice.	LAMA2 DMD	1.61e-06	3	26	2	8568931
Pubmed	Dystroglycan expression in the wild type and mdx mouse neural retina: synaptic colocalization with dystrophin, dystrophin-related protein but not laminin.	LAMA2 DMD	1.61e-06	3	26	2	8568939
Pubmed	Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins.	ARIH1 ARIH2	1.61e-06	3	26	2	10880484
Pubmed	Structure of the HHARI catalytic domain shows glimpses of a HECT E3 ligase.	ARIH1 ARIH2	1.61e-06	3	26	2	24058416
Pubmed	Three mouse models of muscular dystrophy: the natural history of strength and fatigue in dystrophin-, dystrophin/utrophin-, and laminin alpha2-deficient mice.	LAMA2 DMD	1.61e-06	3	26	2	11595512
Pubmed	Overexpression of the cytotoxic T cell (CT) carbohydrate inhibits muscular dystrophy in the dyW mouse model of congenital muscular dystrophy 1A.	LAMA2 DMD	1.61e-06	3	26	2	17591965
Pubmed	The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation.	NSD1 NSD2	1.61e-06	3	26	2	37150325
Pubmed	Loss of dystrophin and β-sarcoglycan significantly exacerbates the phenotype of laminin α2 chain-deficient animals.	LAMA2 DMD	1.61e-06	3	26	2	24393714
Pubmed	Altered expression of the alpha7beta1 integrin in human and murine muscular dystrophies.	LAMA2 DMD	3.22e-06	4	26	2	9427295
Pubmed	Bortezomib partially improves laminin α2 chain-deficient muscular dystrophy.	LAMA2 DMD	3.22e-06	4	26	2	24631023
Pubmed	Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.	LRP1 LRP2	3.22e-06	4	26	2	7775583
Pubmed	The involvement of collagen triple helix repeat containing 1 in muscular dystrophies.	LAMA2 DMD	3.22e-06	4	26	2	23274062
Pubmed	Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.	LRP1 LRP2	3.22e-06	4	26	2	11421580
Pubmed	Elevated Expression of Moesin in Muscular Dystrophies.	LAMA2 DMD	3.22e-06	4	26	2	28082118
Pubmed	Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.	LAMA2 DMD	3.22e-06	4	26	2	18345011
Pubmed	Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.	LRP1 LRP2	3.22e-06	4	26	2	12413896
Pubmed	Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain.	ARIH1 ARIH2	3.22e-06	4	26	2	35716664
Pubmed	Muscle-specific BCL2 expression ameliorates muscle disease in laminin {alpha}2-deficient, but not in dystrophin-deficient, mice.	LAMA2 DMD	3.22e-06	4	26	2	15757977
Pubmed	EMRE is essential for mitochondrial calcium uniporter activity in a mouse model.	LAMA2 DMD	5.37e-06	5	26	2	32017711
Pubmed	miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy.	LAMA2 DMD	5.37e-06	5	26	2	26999812
Pubmed	ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.	LRP1 LRP2	5.37e-06	5	26	2	16101684
Pubmed	TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain.	TAFA4 TAFA2	5.37e-06	5	26	2	15028294
Pubmed	Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles.	LAMA2 DMD	5.37e-06	5	26	2	10024132
Pubmed	Pax7, Pax3 and Mamstr genes are involved in skeletal muscle impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD.	LAMA2 DMD	5.37e-06	5	26	2	31348492
Pubmed	A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation.	NSD1 NSD2	5.37e-06	5	26	2	33135541
Pubmed	Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.	LRP1 LRP2	5.37e-06	5	26	2	19047013
Pubmed	Ex vivo stretch reveals altered mechanical properties of isolated dystrophin-deficient hearts.	LAMA2 DMD	5.37e-06	5	26	2	22427904
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN2A SCN4A	5.37e-06	5	26	2	17724025
Pubmed	Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.	LRP1 LRP2	5.37e-06	5	26	2	18685438
Pubmed	Cib2 binds integrin alpha7Bbeta1D and is reduced in laminin alpha2 chain-deficient muscular dystrophy.	LAMA2 DMD	8.05e-06	6	26	2	18611855
Pubmed	Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.	NSD1 NSD2	8.05e-06	6	26	2	24019522
Pubmed	Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.	LRP1 LRP2	8.05e-06	6	26	2	9837937
Pubmed	The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.	NSD2 CHD5 NSD3	1.06e-05	57	26	3	21555454
Pubmed	Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling.	ARIH1 ARIH2	1.13e-05	7	26	2	12234920
Pubmed	The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.	LRP1 LRP2	1.13e-05	7	26	2	12169628
Pubmed	Cytoplasmic gamma-actin expression in diverse animal models of muscular dystrophy.	LAMA2 DMD	1.13e-05	7	26	2	17475492
Pubmed	Caveolin-3 deficiency causes muscle degeneration in mice.	LAMA2 DMD	1.50e-05	8	26	2	11115849
Pubmed	A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4.	ARIH1 ARIH2	1.50e-05	8	26	2	10431818
Pubmed	Differential regulation of PML-RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1.	ARIH1 ARIH2	1.50e-05	8	26	2	22037423
Pubmed	Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.	DMD SCN4A	1.50e-05	8	26	2	9412493
Pubmed	LDL receptor-related protein as a component of the midkine receptor.	LRP1 LRP2	1.93e-05	9	26	2	10772929
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN2A SCN4A	1.93e-05	9	26	2	15746173
Pubmed	Genetic modifiers of muscular dystrophy: implications for therapy.	LAMA2 DMD	1.93e-05	9	26	2	16916601
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN2A SCN4A	1.93e-05	9	26	2	16382098
Pubmed	Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms.	ARIH1 ARIH2	2.41e-05	10	26	2	27312108
Pubmed	AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.	LAMA2 DMD	2.41e-05	10	26	2	18434328
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP1 LRP2	2.94e-05	11	26	2	24639464
Pubmed	Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers.	LAMA2 DMD	2.94e-05	11	26	2	21989910
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NSD1 CHD3 KMT2D	3.27e-05	83	26	3	28794006
Pubmed	Stage-specific association of apolipoprotein A-I and E in developing mouse retina.	LRP1 LRP2	4.86e-05	14	26	2	17389516
Pubmed	TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.	ARIH1 ARIH2	4.86e-05	14	26	2	24076655
Pubmed	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.	LRP1 LRP2	4.86e-05	14	26	2	15082773
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	ANKIB1 ARIH1 ARIH2	4.90e-05	95	26	3	29643511
Pubmed	DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.	CHD3 CHD5	5.61e-05	15	26	2	35695185
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	LRP1 LRP2 PTPRA	5.89e-05	101	26	3	23382219
Pubmed	A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.	CHD3 CHD5	7.26e-05	17	26	2	27806305
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	NSD1 NSD2 NSD3	7.39e-05	109	26	3	33554859
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	NSD1 CHD3 NSD2 CHD5 NSD3	7.79e-05	608	26	5	36089195
Pubmed	Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.	LRP1 LRP2	8.16e-05	18	26	2	10827173
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP1 LRP2	1.12e-04	21	26	2	21337463
Pubmed	Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.	ARIH1 ARIH2	1.23e-04	22	26	2	30587576
Pubmed	Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.	LAMA2 CCN4	1.23e-04	22	26	2	28334989
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NSD1 STK36 KMT2D NSD2 CHD5 NSD3	1.35e-04	1105	26	6	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	LRP1 LRP2 CHD3 NSD2 CHD5 NSD3	1.43e-04	1116	26	6	31753913
Pubmed	Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.	LAMA2 DMD	1.60e-04	25	26	2	19373938
Pubmed	Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.	PTPRA TAFA2	1.73e-04	26	26	2	36178190
Interaction	ZFP41 interactions	LRP1 LRP2 ARIH1 ARIH2	8.21e-07	57	26	4	int:ZFP41
Interaction	SIN3B interactions	CHD3 NSD2 CHD5 SCN2A SCN4A	1.12e-06	147	26	5	int:SIN3B
Interaction	CCN2 interactions	LRP1 LRP2 ARIH1	1.82e-05	40	26	3	int:CCN2
Interaction	ZDHHC15 interactions	LRP1 LRP2 LAMA2 DMD	1.90e-05	125	26	4	int:ZDHHC15
Interaction	LIFR interactions	LRP1 TAFA4 TAFA2	2.44e-05	44	26	3	int:LIFR
Interaction	TWIST1 interactions	NSD1 CHD3 NSD2 NSD3	6.32e-05	170	26	4	int:TWIST1
GeneFamily	PHD finger proteins	NSD1 CHD3 KMT2D NSD2 CHD5 NSD3	2.27e-10	90	18	6	88
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD1 KMT2D NSD2 NSD3	3.13e-08	34	18	4	487
GeneFamily	PWWP domain containing	NSD1 NSD2 NSD3	1.26e-06	22	18	3	1147
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN2A SCN4A	3.36e-05	9	18	2	1203
GeneFamily	PHD finger proteins\|NuRD complex	CHD3 CHD5	6.14e-05	12	18	2	1305
GeneFamily	Low density lipoprotein receptors	LRP1 LRP2	7.25e-05	13	18	2	634
Coexpression	GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN	NSD1 PTPRA NSD3 SCN4A	2.34e-05	171	26	4	M8820
Coexpression	GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_DN	LRP1 CHD3 KMT2D ARIH2	4.31e-05	200	26	4	M6585
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	5.18e-08	175	26	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	5.33e-08	176	26	5	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	5.33e-08	176	26	5	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	6.65e-08	184	26	5	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.00e-08	191	26	5	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.00e-08	191	26	5	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.00e-08	191	26	5	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.00e-08	191	26	5	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.00e-08	191	26	5	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.00e-08	191	26	5	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.22e-08	192	26	5	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.22e-08	192	26	5	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.22e-08	192	26	5	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.22e-08	192	26	5	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.43e-08	193	26	5	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.65e-08	194	26	5	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.65e-08	194	26	5	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.65e-08	194	26	5	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.65e-08	194	26	5	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.87e-08	195	26	5	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.87e-08	195	26	5	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.87e-08	195	26	5	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	8.87e-08	195	26	5	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	9.34e-08	197	26	5	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1 DMD	9.34e-08	197	26	5	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D231\|Adult / Lineage, Cell type, age group and donor	LAMA2 CCN4 PLA2G5 ITGBL1	2.39e-06	164	26	4	3d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	2.89e-06	172	26	4	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	2.89e-06	172	26	4	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMA2 CCN4 ITGBL1 DMD	3.09e-06	175	26	4	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	3.23e-06	177	26	4	b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 CCN4 PLA2G5 ITGBL1	3.31e-06	178	26	4	27497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 CCN4 PLA2G5 ITGBL1	3.31e-06	178	26	4	d348a9550db940d204706529759dc51e30506b5f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	3.31e-06	178	26	4	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	3.61e-06	182	26	4	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	3.61e-06	182	26	4	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 LAMA2 CCN4 ITGBL1	3.69e-06	183	26	4	7e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 LAMA2 CCN4 ITGBL1	3.69e-06	183	26	4	63294d66e3ccf152ffe5d1237106764c14390b62
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMA2 CCN4 ITGBL1 TAFA4	3.69e-06	183	26	4	bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 STK36 DMD SCN2A	3.77e-06	184	26	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LRP1 LAMA2 CCN4 ITGBL1	3.77e-06	184	26	4	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 STK36 DMD SCN2A	3.77e-06	184	26	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 STK36 DMD SCN2A	3.77e-06	184	26	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	3.77e-06	184	26	4	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 LAMA2 CCN4 ITGBL1	3.94e-06	186	26	4	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	LRP1 LAMA2 PLA2G5 ITGBL1	4.02e-06	187	26	4	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	LAMA2 CCN4 ITGBL1 FGFBP2	4.11e-06	188	26	4	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 ITGBL1 DMD	4.11e-06	188	26	4	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	4.19e-06	189	26	4	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	4.19e-06	189	26	4	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 ITGBL1 DMD	4.28e-06	190	26	4	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	4.37e-06	191	26	4	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1	4.56e-06	193	26	4	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1	4.56e-06	193	26	4	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1	4.65e-06	194	26	4	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1	4.65e-06	194	26	4	29f83cdd63314fff41258937d70b881a5503bfcc
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1	4.65e-06	194	26	4	d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	4.65e-06	194	26	4	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	4.65e-06	194	26	4	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	LRP1 LAMA2 PLA2G5 ITGBL1	4.75e-06	195	26	4	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 LRP2 LAMA2 DMD	4.84e-06	196	26	4	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 ITGBL1 DMD	4.84e-06	196	26	4	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 LRP2 LAMA2 DMD	4.84e-06	196	26	4	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	4.84e-06	196	26	4	b8759e6231e0254797d6c30930407b79440c57bb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 ITGBL1 DMD	4.84e-06	196	26	4	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 CCN4 ITGBL1	4.94e-06	197	26	4	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1 DMD	4.94e-06	197	26	4	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRP1 LAMA2 CCN4 ITGBL1	5.04e-06	198	26	4	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	metastatic_Brain-Fibroblasts-FB-like_cells\|metastatic_Brain / Location, Cell class and cell subclass	LAMA2 CCN4 PLA2G5 ITGBL1	5.14e-06	199	26	4	12133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_adventitial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	LRP1 LAMA2 PLA2G5 ITGBL1	5.25e-06	200	26	4	9dd2eb70c1cc146935f5aff27373dfc65cb8c098
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LRP1 LAMA2 PLA2G5 ITGBL1	5.25e-06	200	26	4	74ad0ae592252060ee294d7483327d765a6ba1dd
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LRP1 LAMA2 CCN4 ITGBL1	5.25e-06	200	26	4	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	LRP1 LAMA2 PLA2G5 ITGBL1	5.25e-06	200	26	4	5fdca7959134a5c8e06e5d6d14aafe34b963aef2
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LRP1 LAMA2 PLA2G5 ITGBL1	5.25e-06	200	26	4	7ba292c30d915e66ebc8026fa76492cedf64700e
ToppCell	Tracheal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LRP1 LAMA2 PLA2G5 ITGBL1	5.25e-06	200	26	4	920e6036c0a9c0089d0d898673daf9dd9d7279fc
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRP1 LAMA2 CCN4 ITGBL1	5.25e-06	200	26	4	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Bronchial_Biopsy-Mesenchymal-Fibroblasts\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	LRP1 LAMA2 ITGBL1	5.70e-05	129	26	3	13cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 UGT3A2 SCN2A	9.10e-05	151	26	3	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 ITGBL1 DMD	9.47e-05	153	26	3	1524557514668f515ac1bbe847611f564b265b42
ToppCell	367C-Fibroblasts-Fibroblast-D-\|367C / Donor, Lineage, Cell class and subclass (all cells)	LRP1 LAMA2 UGT3A2	9.65e-05	154	26	3	dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell	367C-Fibroblasts-Fibroblast-D\|367C / Donor, Lineage, Cell class and subclass (all cells)	LRP1 LAMA2 UGT3A2	9.65e-05	154	26	3	4bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 ITGBL1 DMD	9.84e-05	155	26	3	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMA2 CCN4 DMD	1.00e-04	156	26	3	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ITGBL1 DMD	1.00e-04	156	26	3	363f1b661048d25895e2b8681c82894c957b29c0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ITGBL1 DMD	1.00e-04	156	26	3	d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 CCN4 ITGBL1	1.02e-04	157	26	3	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 CCN4 ITGBL1	1.12e-04	162	26	3	bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 ITGBL1 DMD	1.20e-04	166	26	3	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	Adult-Mesenchymal-myofibroblast_cell\|Adult / Lineage, Cell type, age group and donor	LAMA2 CCN4 ITGBL1	1.23e-04	167	26	3	d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 ITGBL1	1.25e-04	168	26	3	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 LAMA2 ITGBL1	1.27e-04	169	26	3	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 LAMA2 ITGBL1	1.27e-04	169	26	3	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1 LAMA2 ITGBL1	1.27e-04	169	26	3	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ITGBL1 DMD	1.29e-04	170	26	3	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ITGBL1 DMD	1.29e-04	170	26	3	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1 LAMA2 ITGBL1	1.32e-04	171	26	3	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRP1 LAMA2 ITGBL1	1.34e-04	172	26	3	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 LAMA2 SCN4A	1.43e-04	176	26	3	c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LRP1 LAMA2 ITGBL1	1.43e-04	176	26	3	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LRP1 LAMA2 ITGBL1	1.43e-04	176	26	3	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 ITGBL1 DMD	1.46e-04	177	26	3	b59967219f7d874805768e247c0eb2bc4d4420c8
Drug	mu-conotoxin KIIIA, Conus kinoshitai	SCN2A SCN4A	1.25e-06	2	26	2	ctd:C502265
Drug	strontium titanate	NSD1 STK36	3.76e-06	3	26	2	CID000082899
Drug	Fospropofol	SCN2A SCN4A	7.51e-06	4	26	2	DB06716
Drug	Propofol	SCN2A SCN4A	7.51e-06	4	26	2	DB00818
Drug	APETx1, Anthopleura elegantissima	SCN2A SCN4A	1.88e-05	6	26	2	ctd:C475726
Drug	fluorocyclobutane	SCN2A SCN4A	2.62e-05	7	26	2	CID011051569
Drug	tricarballylate	NSD1 NSD2 NSD3	4.12e-05	59	26	3	CID000014925
Drug	coprogen	LRP1 LRP2	4.49e-05	9	26	2	CID006323272
Drug	25-azacoprostane	LRP1 LRP2	5.61e-05	10	26	2	CID000162243
Drug	Thiamphenicol [15318-45-3]; Down 200; 11.2uM; HL60; HT_HG-U133A	NSD1 CHD3 NSD3 ARIH2	6.73e-05	195	26	4	1867_DN
Drug	Propidium iodide [25535-16-4]; Up 200; 6uM; MCF7; HT_HG-U133A	LRP2 PLA2G5 CHD5 NSD3	7.00e-05	197	26	4	6277_UP
Drug	Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A	PLA2G5 NSD2 NSD3 ARIH2	7.14e-05	198	26	4	6455_UP
Drug	Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; HL60; HG-U133A	LRP1 PLA2G5 CHD3 PTPRA	7.14e-05	198	26	4	1985_UP
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; PC3; HT_HG-U133A	LRP2 DMD SCN2A NSD3	7.28e-05	199	26	4	4485_UP
Drug	PHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A	LRP1 LRP2 LAMA2 CHD3	7.42e-05	200	26	4	3827_DN
Drug	20(S)-Propanaxidiol	SCN2A SCN4A	9.71e-05	13	26	2	CID005317623
Drug	peonidin	STK36 SCN2A	1.13e-04	14	26	2	CID000164544
Drug	nonanol	SCN2A SCN4A	1.30e-04	15	26	2	CID000008914
Disease	Sotos syndrome 1 (implicated_via_orthology)	NSD1 NSD2 NSD3	6.07e-10	3	26	3	DOID:0112103 (implicated_via_orthology)
Disease	syndrome (implicated_via_orthology)	NSD1 NSD2 NSD3	4.91e-07	18	26	3	DOID:225 (implicated_via_orthology)
Disease	Muscular Dystrophy	LAMA2 DMD	2.08e-05	8	26	2	C0026850
Disease	Malignant neoplasm of breast	LAMA2 KMT2D DMD TAFA4 NSD2 FOLR2 CHD5	2.97e-05	1074	26	7	C0006142
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN2A SCN4A	3.35e-05	10	26	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN2A SCN4A	3.35e-05	10	26	2	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN2A SCN4A	4.90e-05	12	26	2	DOID:0060170 (implicated_via_orthology)
Disease	muscular dystrophy (implicated_via_orthology)	LAMA2 DMD	1.55e-04	21	26	2	DOID:9884 (implicated_via_orthology)
Disease	Sezary Syndrome	CHD3 KMT2D	2.59e-04	27	26	2	C0036920
Disease	Colorectal Carcinoma	LRP1 LRP2 UGT3A2 DMD CHD5	3.26e-04	702	26	5	C0009402
Disease	epilepsy (implicated_via_orthology)	LRP1 SCN2A SCN4A	3.92e-04	163	26	3	DOID:1826 (implicated_via_orthology)
Disease	threonine measurement	ITGBL1 TAFA2	4.88e-04	37	26	2	EFO_0009775
Disease	Intellectual Disability	LRP2 NSD1 CHD3 NSD2	5.96e-04	447	26	4	C3714756
Disease	pain	LRP1 NSD1 LAMA2	6.70e-04	196	26	3	EFO_0003843
Disease	Gastrointestinal Stromal Sarcoma	STK36 DMD	7.88e-04	47	26	2	C3179349

Protein segments in the cluster

Peptide	Gene	Start	Entry
KWSCPHCEKEGIQWE	CHD5	381	Q8TDI0
EAHEPCDCQTWKNWL	ANKIB1	471	Q9P2G1
SKCKHDFCWMCLGDW	ARIH2	316	O95376
PGHCCEQWVCEDDAK	CCN4	176	O95388
GKCKTLEEVWACWHE	DMD	1256	P11532
KWECPWHQCDICGKE	NSD1	2156	Q96L73
NCGENWHDPVKCKWL	ARIH1	306	Q9Y4X5
NCKAEFCWVCLGPWE	ARIH1	366	Q9Y4X5
CKNDKCIPFWWKCDT	LRP1	3341	Q07954
CIPFWWKCDTEDDCG	LRP1	3346	Q07954
GKWECPWHHCDVCGK	NSD2	1276	O96028
KAWEHCWKPFQALCA	FGFBP2	201	Q9BYJ0
HPWCAWDICEAWAEK	GNL1	471	P36915
KCDGCKHWHAREGWE	LAMA2	1556	P24043
IPIWWKCDGQKDCSD	LRP2	3526	P98164
PKDGTDWCCWAHDHC	PLA2G5	56	P39877
GKWSCPHCEKEGVQW	CHD3	416	Q12873
VPLCKEDCQRWWEDC	FOLR2	126	P14207
WHGDKCEFQCDITPW	ITGBL1	211	O95965
KECKCAQYWPDQGCW	PTPRA	346	P18433
EQKWWCHMQPCLEGE	TAFA2	91	Q8N3H0
QKWWCHMNPCLEGED	TAFA4	101	Q96LR4
CAHKVLIWNCCAPWL	SCN4A	551	P35499
GLPDCWDAKEQVCWH	STK36	671	Q9NRP7
CLIWDCCKPWLKVKH	SCN2A	736	Q99250
PYGKWECPWHQCDEC	NSD3	1356	Q9BZ95
GVIWKCQCSHWPKDV	UGT3A2	326	Q3SY77
HKIPCHCGAWNCRKW	KMT2D	5521	O14686