Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	neuropeptide Y receptor activity	QRFPR NPY4R2 NPY4R	5.57e-05	11	142	3	GO:0004983
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DYNC2H1 DNAH2 DNAH9	2.66e-04	18	142	3	GO:0008569
GeneOntologyMolecularFunction	pancreatic polypeptide receptor activity	NPY4R2 NPY4R	2.98e-04	4	142	2	GO:0001602
GeneOntologyMolecularFunction	microtubule binding	KIF21B STRBP KATNB1 APC ZNF207 DRG1 CEP350 TUBGCP3 VPS41	3.66e-04	308	142	9	GO:0008017
GeneOntologyBiologicalProcess	negative regulation of phospholipase A2 activity	ANXA8L1 ANXA8 PLA2R1	3.26e-07	3	143	3	GO:1900138
GeneOntologyBiologicalProcess	negative regulation of phospholipase activity	ANXA8L1 ANXA8 PLA2R1	3.23e-06	5	143	3	GO:0010519
GeneOntologyBiologicalProcess	microtubule-based process	ADCY10 KIF21B KAT5 RNF19A DYNC2H1 KATNB1 DNAH2 APC ZNF207 SPECC1L STIL DRG1 CEP350 FSIP2 INTS13 INSC TUBGCP3 KLHL42 ULK4 ROCK1 DNAH9	1.31e-05	1058	143	21	GO:0007017
GeneOntologyBiologicalProcess	regulation of phospholipase A2 activity	ANXA8L1 ANXA8 PLA2R1	3.78e-05	10	143	3	GO:0032429
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	KAT5 RNF19A KATNB1 DNAH2 APC ZNF207 SPECC1L STIL DRG1 CEP350 FSIP2 INTS13 INSC TUBGCP3 ULK4 ROCK1	4.08e-05	720	143	16	GO:0000226
GeneOntologyCellularComponent	distal axon	ADCY10 KIF21B ITSN1 KATNB1 APBB1 APBB2 APC GRIK4 TBC1D24 PTK2B SNAP91	2.33e-04	435	145	11	GO:0150034
GeneOntologyCellularComponent	presynaptic endocytic zone	ITSN1 PICALM SNAP91	2.47e-04	18	145	3	GO:0098833
HumanPheno	Abnormal eyelid morphology	EPHX2 KDM5B KAT5 ABCA12 DYNC2H1 POLA1 KRT85 KATNB1 CARS1 POLRMT APC SPECC1L HUWE1 STIL MKS1 TBC1D24 WAC DRG1 TGFBR1 COG1 SCAPER LRP4 CYP4F22 UMPS PLCB4 EXOC2 CTNND2 BRAT1 ERMARD	9.81e-07	1408	47	29	HP:0000492
Domain	ARM-type_fold	RELCH APC HUWE1 EFR3A THADA ATP6V1H MROH8 INSC ULK4 UTP20 CTNND2 BRAT1 IPO11	1.81e-06	339	141	13	IPR016024
Domain	ARM-like	RELCH APC HUWE1 EFR3A ATP6V1H INSC ULK4 UTP20 CTNND2 BRAT1 IPO11	6.58e-06	270	141	11	IPR011989
Domain	-	RELCH APC EFR3A ATP6V1H INSC ULK4 UTP20 CTNND2 BRAT1 IPO11	7.31e-06	222	141	10	1.25.10.10
Domain	DHC_N1	DYNC2H1 DNAH2 DNAH9	2.29e-05	8	141	3	PF08385
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH2 DNAH9	2.29e-05	8	141	3	IPR013594
Domain	NPY_rcpt	QRFPR NPY4R2 NPY4R	3.42e-05	9	141	3	IPR000611
Domain	AnnexinVIII	ANXA8L1 ANXA8	5.66e-05	2	141	2	IPR009115
Domain	Clathrin_AP_2	PICALM SNAP91	5.66e-05	2	141	2	IPR014712
Domain	NPY4_rcpt	NPY4R2 NPY4R	5.66e-05	2	141	2	IPR001933
Domain	-	PICALM SNAP91	5.66e-05	2	141	2	1.20.58.150
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH2 DNAH9	1.44e-04	14	141	3	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH2 DNAH9	1.44e-04	14	141	3	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH2 DNAH9	1.44e-04	14	141	3	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH2 DNAH9	1.44e-04	14	141	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH2 DNAH9	1.44e-04	14	141	3	IPR011704
Domain	MT	DYNC2H1 DNAH2 DNAH9	1.44e-04	14	141	3	PF12777
Domain	AAA_8	DYNC2H1 DNAH2 DNAH9	1.44e-04	14	141	3	PF12780
Domain	AAA_5	DYNC2H1 DNAH2 DNAH9	1.44e-04	14	141	3	PF07728
Domain	SPAR_C	SIPA1L3 SIPA1L1	1.69e-04	3	141	2	PF11881
Domain	TMED7	TMED7 TMED3	1.69e-04	3	141	2	IPR015718
Domain	SIPA1L_C	SIPA1L3 SIPA1L1	1.69e-04	3	141	2	IPR021818
Domain	DHC_fam	DYNC2H1 DNAH2 DNAH9	1.79e-04	15	141	3	IPR026983
Domain	Dynein_heavy	DYNC2H1 DNAH2 DNAH9	1.79e-04	15	141	3	PF03028
Domain	Dynein_heavy_dom	DYNC2H1 DNAH2 DNAH9	1.79e-04	15	141	3	IPR004273
Domain	HEAT_REPEAT	RELCH ULK4 UTP20 BRAT1 IPO11	1.86e-04	70	141	5	PS50077
Domain	ANTH_dom	PICALM SNAP91	3.36e-04	4	141	2	IPR011417
Domain	ANTH	PICALM SNAP91	3.36e-04	4	141	2	PF07651
Domain	WW	APBB1 APBB2 ARHGAP39 WAC	4.32e-04	47	141	4	PF00397
Domain	WW	APBB1 APBB2 ARHGAP39 WAC	4.68e-04	48	141	4	SM00456
Domain	WW_DOMAIN_1	APBB1 APBB2 ARHGAP39 WAC	5.91e-04	51	141	4	PS01159
Domain	WW_DOMAIN_2	APBB1 APBB2 ARHGAP39 WAC	5.91e-04	51	141	4	PS50020
Domain	WW_dom	APBB1 APBB2 ARHGAP39 WAC	6.36e-04	52	141	4	IPR001202
Domain	AAA	ABCA12 DYNC2H1 DNAH2 ABCA10 MCM9 DNAH9	7.90e-04	144	141	6	SM00382
Domain	AAA+_ATPase	ABCA12 DYNC2H1 DNAH2 ABCA10 MCM9 DNAH9	7.90e-04	144	141	6	IPR003593
Domain	RhoGAP	STARD13 ARHGAP39 ARHGAP35 ARAP2	1.24e-03	62	141	4	SM00324
Domain	RhoGAP	STARD13 ARHGAP39 ARHGAP35 ARAP2	1.31e-03	63	141	4	PF00620
Domain	RhoGAP_dom	STARD13 ARHGAP39 ARHGAP35 ARAP2	1.39e-03	64	141	4	IPR000198
Domain	RHOGAP	STARD13 ARHGAP39 ARHGAP35 ARAP2	1.39e-03	64	141	4	PS50238
Domain	-	STARD13 ARHGAP39 ARHGAP35 ARAP2	1.39e-03	64	141	4	1.10.555.10
Domain	ENTH	PICALM SNAP91	1.97e-03	9	141	2	PS50942
Domain	ENTH	PICALM SNAP91	1.97e-03	9	141	2	SM00273
Domain	ENTH	PICALM SNAP91	2.45e-03	10	141	2	IPR013809
Domain	Rap_GAP	SIPA1L3 SIPA1L1	2.45e-03	10	141	2	PF02145
Domain	Rap_GAP_dom	SIPA1L3 SIPA1L1	2.98e-03	11	141	2	IPR000331
Domain	RAPGAP	SIPA1L3 SIPA1L1	2.98e-03	11	141	2	PS50085
Domain	ARM	APC INSC CTNND2	3.39e-03	40	141	3	SM00185
Domain	ABC_A	ABCA12 ABCA10	3.55e-03	12	141	2	IPR026082
Domain	ANX	ANXA8L1 ANXA8	4.18e-03	13	141	2	SM00335
Domain	Annexin_repeat_CS	ANXA8L1 ANXA8	4.18e-03	13	141	2	IPR018252
Domain	Annexin	ANXA8L1 ANXA8	4.18e-03	13	141	2	PF00191
Domain	Annexin_repeat	ANXA8L1 ANXA8	4.18e-03	13	141	2	IPR018502
Domain	ANNEXIN	ANXA8L1 ANXA8	4.18e-03	13	141	2	PS00223
Domain	-	ANXA8L1 ANXA8	4.18e-03	13	141	2	1.10.220.10
Domain	Rho_GTPase_activation_prot	STARD13 ARHGAP39 ARHGAP35 ARAP2	4.45e-03	88	141	4	IPR008936
Domain	Annexin	ANXA8L1 ANXA8	4.85e-03	14	141	2	IPR001464
Domain	FN_type2_col-bd	PLA2R1 LY75	4.85e-03	14	141	2	IPR000562
Domain	FN2_2	PLA2R1 LY75	4.85e-03	14	141	2	PS51092
Domain	FN2_1	PLA2R1 LY75	4.85e-03	14	141	2	PS00023
Domain	fn2	PLA2R1 LY75	4.85e-03	14	141	2	PF00040
Domain	FN2	PLA2R1 LY75	4.85e-03	14	141	2	SM00059
Domain	PH_dom-like	ITSN1 APBB1 APBB2 PTK2B PLEKHA3 OSBPL9 ROCK1 PLCB4 ARAP2	5.10e-03	426	141	9	IPR011993
Domain	Armadillo	APC INSC CTNND2	5.36e-03	47	141	3	IPR000225
Domain	EMP24_GP25L	TMED7 TMED3	5.57e-03	15	141	2	PF01105
Pubmed	Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein.	APBB1 APBB2 APLP2	2.95e-07	4	147	3	8855266
Pubmed	Gene expression profile in fibroblasts of Huntington's disease patients and controls.	APC ROCK1 PLCB4	2.95e-07	4	147	3	24296361
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	DDX19B KDM5B ANKFY1 DYNC2H1 POLA1 KRT85 APC ZNF207 BRCC3 HUWE1 TRMT10C SIPA1L1 TUBGCP3 OSBPL9 KLHL42 UMPS WDR24	1.33e-06	1005	147	17	19615732
Pubmed	Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1.	KAT5 APBB1 APLP2	1.47e-06	6	147	3	14699153
Pubmed	Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP.	KAT5 APBB1 APLP2	4.08e-06	8	147	3	15944124
Pubmed	Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development.	APBB1 APBB2 APLP2	8.69e-06	10	147	3	16407979
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KDM5B VWF ITSN1 SIPA1L3 APBB1 APBB2 APC BRCC3 HUWE1 CPNE5 WAC CEP350 ATF6 COG1 SIPA1L1 ASPA LRP4 CTNND2	8.78e-06	1285	147	18	35914814
Pubmed	Genome-wide association scan of dental caries in the permanent dentition.	EPHX2 APBB2 PTK2B RBMS3	1.14e-05	33	147	4	23259602
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF21B ANKFY1 ITSN1 SIPA1L3 APC SPECC1L ARHGAP39 HUWE1 ATF6B PICALM SNAP91 SIPA1L1 DZIP3 ROCK1 CTNND2	1.53e-05	963	147	15	28671696
Pubmed	Wide-spread enhancer effect of SNP rs2279590 on regulating epoxide hydrolase-2 and protein tyrosine kinase 2-beta gene expression.	EPHX2 PTK2B	1.77e-05	2	147	2	36470481
Pubmed	Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development.	APC TGFBR1	1.77e-05	2	147	2	19147584
Pubmed	TaqI polymorphisms at the annexin VIII locus (ANX8).	ANXA8L1 ANXA8	1.77e-05	2	147	2	1364010
Pubmed	Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins.	PICALM SNAP91	1.77e-05	2	147	2	26399746
Pubmed	Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.	ANXA8L1 ANXA8	1.77e-05	2	147	2	29306076
Pubmed	FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness.	APBB1 APBB2	1.77e-05	2	147	2	25757569
Pubmed	FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation.	APBB1 APBB2	1.77e-05	2	147	2	27734846
Pubmed	Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.	ANXA8L1 ANXA8	1.77e-05	2	147	2	21344395
Pubmed	Annexin A8 is up-regulated during mouse mammary gland involution and predicts poor survival in breast cancer.	ANXA8L1 ANXA8	1.77e-05	2	147	2	16203777
Pubmed	N-glycosylation of ATF6beta is essential for its proteolytic cleavage and transcriptional repressor function to ATF6alpha.	ATF6B ATF6	1.77e-05	2	147	2	19693772
Pubmed	ZnR/GPR39 controls cell migration by orchestrating recruitment of KCC3 into protrusions, re-organization of actin and activation of MMP.	SLC12A6 GPR39	1.77e-05	2	147	2	33465674
Pubmed	Turning CALM into excitement: AP180 and CALM in endocytosis and disease.	PICALM SNAP91	1.77e-05	2	147	2	22639918
Pubmed	TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.	HUWE1 TGFBR1	1.77e-05	2	147	2	28931816
Pubmed	Annexins: from structure to function.	ANXA8L1 ANXA8	1.77e-05	2	147	2	11917092
Pubmed	Sipa1l3/SPAR3 is targeted to postsynaptic specializations and interacts with the Fezzin ProSAPiP1/Lzts3.	SIPA1L3 SIPA1L1	1.77e-05	2	147	2	26364583
Pubmed	Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.	ANXA8L1 ANXA8	1.77e-05	2	147	2	24769558
Pubmed	A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60.	KAT5 APBB1	1.77e-05	2	147	2	11441186
Pubmed	A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin Binding and Assembly.	PICALM SNAP91	1.77e-05	2	147	2	27574975
Pubmed	A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.	ATF6B ATF6	1.77e-05	2	147	2	12782636
Pubmed	Annexins: linking Ca2+ signalling to membrane dynamics.	ANXA8L1 ANXA8	1.77e-05	2	147	2	15928709
Pubmed	PLU1 histone demethylase decreases the expression of KAT5 and enhances the invasive activity of the cells.	KDM5B KAT5	1.77e-05	2	147	2	21574959
Pubmed	Inhibitory role of Gas6 in intestinal tumorigenesis.	GAS6 APC	1.77e-05	2	147	2	23430954
Pubmed	Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5.	ITSN1 TGFBR1	1.77e-05	2	147	2	25720380
Pubmed	Partial limitation of cellular functions and compensatory modulation of unfolded protein response pathways caused by double-knockout of ATF6α and ATF6β.	ATF6B ATF6	1.77e-05	2	147	2	38320450
Pubmed	Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress.	ATF6B ATF6	1.77e-05	2	147	2	20631254
Pubmed	Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.	ANXA8L1 ANXA8	1.77e-05	2	147	2	25803307
Pubmed	Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction.	ATF6B ATF6	1.77e-05	2	147	2	14973138
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DDX19B KDM5B SIPA1L3 C19orf47 APBB1 APC BRCC3 STIL CEP350 FSIP2 PTK2B SIPA1L1 PLEKHA3 ARAP2	1.86e-05	861	147	14	36931259
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KAT5 ACTBL2 SIPA1L3 POLRMT APC TMED7 ZNF207 APLP2 SPECC1L ARHGAP39 MED1 DRG1 EFR3A TRMT10C INTS13 SIPA1L1 UTP20 EXOC2 CTNND2	1.93e-05	1497	147	19	31527615
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	POLA1 APC ZNF207 ARHGAP35 PICALM CEP350 THADA SCAPER UMPS ROCK1 CCDC25 IPO11	3.91e-05	689	147	12	36543142
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	STARD13 RELCH ZNF143 DYNC2H1 ACTBL2 CCDC150 ZNF207 APLP2 MED1 MKS1 DRG1 THADA SIPA1L1 DZIP3 EXOC2 WDR24 IPO11	4.60e-05	1321	147	17	27173435
Pubmed	Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.	ACTBL2 APC STIL CEP350	5.16e-05	48	147	4	27872092
Pubmed	The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner.	APBB1 APBB2	5.31e-05	3	147	2	11544248
Pubmed	Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo.	EPHX2 ATF6	5.31e-05	3	147	2	22354938
Pubmed	Specific expression of annexin A8 in adult murine stratified epithelia.	ANXA8L1 ANXA8	5.31e-05	3	147	2	17082908
Pubmed	Tau regulates the microtubule-dependent migration of glioblastoma cells via the Rho-ROCK signaling pathway.	ARHGAP35 ROCK1	5.31e-05	3	147	2	30659115
Pubmed	Pseudoexfoliation and Alzheimer's associated CLU risk variant, rs2279590, lies within an enhancer element and regulates CLU, EPHX2 and PTK2B gene expression.	EPHX2 PTK2B	5.31e-05	3	147	2	28973302
Pubmed	E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.	APC HUWE1	5.31e-05	3	147	2	28137882
Pubmed	Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors.	ATF6B ATF6	5.31e-05	3	147	2	9837962
Pubmed	Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.	APBB1 APBB2	5.31e-05	3	147	2	9546346
Pubmed	Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart.	ATF6B ATF6	5.31e-05	3	147	2	30765833
Pubmed	Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1.	ATF6B ATF6	5.31e-05	3	147	2	17765680
Pubmed	RapGAPs in brain: multipurpose players in neuronal Rap signalling.	SIPA1L3 SIPA1L1	5.31e-05	3	147	2	20576033
Pubmed	Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X.	ATF6B ATF6	5.31e-05	3	147	2	29522813
Pubmed	Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.	NPY4R2 NPY4R	5.31e-05	3	147	2	8643460
Pubmed	Vascular anticoagulant beta: a novel human Ca2+/phospholipid binding protein that inhibits coagulation and phospholipase A2 activity. Its molecular cloning, expression and comparison with VAC-alpha.	ANXA8L1 ANXA8	5.31e-05	3	147	2	2530088
Pubmed	The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor.	KAT5 APBB1	5.31e-05	3	147	2	15331662
Pubmed	IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers.	APC IPO11	5.31e-05	3	147	2	31881079
Pubmed	Cenani-Lenz syndrome and other related syndactyly disorders due to variants in LRP4, GREM1/FMN1, and APC: Insight into the pathogenesis and the relationship to polyposis through the WNT and BMP antagonistic pathways.	APC LRP4	5.31e-05	3	147	2	30569497
Pubmed	Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing.	CXorf38 ERMARD	5.31e-05	3	147	2	23768067
Pubmed	The clathrin assembly protein AP180 regulates the generation of amyloid-beta peptide.	PICALM SNAP91	5.31e-05	3	147	2	19450545
Pubmed	Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor.	PTK2B ROCK1	5.31e-05	3	147	2	16760434
Pubmed	The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity.	ATF6B ATF6	5.31e-05	3	147	2	34158584
Pubmed	Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission.	ITSN1 SNAP91	5.31e-05	3	147	2	31940485
Pubmed	Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.	PICALM SNAP91	5.31e-05	3	147	2	35613266
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	KIF21B RELCH ANKFY1 RNF166 ITSN1 POLRMT APLP2 BRCC3 HUWE1 MED1 TMED3	5.57e-05	604	147	11	38803224
Pubmed	A protein interaction landscape of breast cancer.	SDSL SIPA1L3 CARS1 POLRMT BRCC3 SPECC1L PICALM DRG1 ATP6V1H MCM9 UMPS	8.57e-05	634	147	11	34591612
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	KIF21B ITSN1 ARHGAP39 HUWE1 SNAP91 CCDC25 CTNND2	8.94e-05	246	147	7	15345747
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	DDX19B ZNF143 ANKFY1 DYNC2H1 STRBP DNAH2 APBB1 MED1 CEP350 INTS13 CTNND2	9.05e-05	638	147	11	31182584
Pubmed	Mapping of the human and murine X11-like genes (APBA2 and apba2), the murine Fe65 gene (Apbb1), and the human Fe65-like gene (APBB2): genes encoding phosphotyrosine-binding domain proteins that interact with the Alzheimer's disease amyloid precursor protein.	APBB1 APBB2	1.06e-04	4	147	2	9585438
Pubmed	Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response.	ATF6B ATF6	1.06e-04	4	147	2	11158310
Pubmed	TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function.	APC TGFBR1	1.06e-04	4	147	2	28368414
Pubmed	Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interaction.	KAT5 APBB1	1.06e-04	4	147	2	17368826
Pubmed	Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation.	KAT5 APBB1	1.06e-04	4	147	2	15044485
Pubmed	Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression.	APBB1 APBB2	1.06e-04	4	147	2	12089154
Pubmed	The VWF/LRP4/αVβ3-axis represents a novel pathway regulating proliferation of human vascular smooth muscle cells.	VWF LRP4	1.06e-04	4	147	2	33576766
Pubmed	APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration.	APC TGFBR1	1.06e-04	4	147	2	22496417
Pubmed	The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system.	APBB1 APBB2	1.06e-04	4	147	2	8955346
Pubmed	Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein.	APBB1 APLP2	1.06e-04	4	147	2	9461550
Pubmed	Identification of 4 new HLA-DR-restricted minor histocompatibility antigens as hematopoietic targets in antitumor immunity.	PTK2B LY75	1.06e-04	4	147	2	19706888
Pubmed	ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.	ATF6B ATF6	1.06e-04	4	147	2	11163209
Pubmed	Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice.	ATF6B ATF6	1.06e-04	4	147	2	36696173
Pubmed	Sledgehammer to Scalpel: Broad Challenges to the Heart and Other Tissues Yield Specific Cellular Responses via Transcriptional Regulation of the ER-Stress Master Regulator ATF6α.	ATF6B ATF6	1.06e-04	4	147	2	32046286
Pubmed	The intracellular domain of the low density lipoprotein receptor-related protein modulates transactivation mediated by amyloid precursor protein and Fe65.	KAT5 APBB1	1.06e-04	4	147	2	12888553
Pubmed	XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response.	ATF6B ATF6	1.06e-04	4	147	2	14559994
Pubmed	A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.	ARHGAP35 PTK2B	1.06e-04	4	147	2	19435801
Pubmed	cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.	APBB1 APLP2	1.06e-04	4	147	2	8894693
Pubmed	Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.	APC HUWE1	1.06e-04	4	147	2	27184401
Pubmed	A ternary complex consisting of AICD, FE65, and TIP60 down-regulates Stathmin1.	KAT5 APBB1	1.06e-04	4	147	2	22902274
Pubmed	Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks.	KAT5 APBB1	1.06e-04	4	147	2	19282473
Pubmed	Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY.	NPY4R2 NPY4R	1.06e-04	4	147	2	7592911
Pubmed	FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β.	APC PTK2B	1.06e-04	4	147	2	26274564
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SLC12A6 VWF ITSN1 ACTBL2 SIPA1L3 APC SPECC1L ARHGAP39 ARHGAP35 TBC1D24 PTK2B ATP6V1H SNAP91 SIPA1L1 SCAPER OSBPL9 CTNND2	1.22e-04	1431	147	17	37142655
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	RELCH ANKFY1 ITSN1 PICALM	1.24e-04	60	147	4	34761192
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	ITSN1 APBB1 APBB2 APC PTK2B	1.62e-04	120	147	5	31413325
Pubmed	Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load.	KAT5 APBB1	1.76e-04	5	147	2	33849647
Pubmed	Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY.	NPY4R2 NPY4R	1.76e-04	5	147	2	7493937
Pubmed	Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.	APC TGFBR1	1.76e-04	5	147	2	31526760
Pubmed	Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein.	APBB1 APLP2	1.76e-04	5	147	2	10081969
Pubmed	Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.	PICALM SNAP91	1.76e-04	5	147	2	10436022
Pubmed	Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.	KAT5 APBB1	1.76e-04	5	147	2	25342469
Interaction	NPTN interactions	DDX19B DYNC2H1 ACTBL2 HUWE1 THADA ATP6V1H COG1 UTP20 EXOC2 BRAT1 IPO11	3.46e-06	278	138	11	int:NPTN
GeneFamily	Transmembrane p24 trafficking proteins	TMED7 TMED3	1.38e-03	10	102	2	1064
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	APC THADA CTNND2	1.83e-03	43	102	3	409
GeneFamily	Annexins\|Endogenous ligands	ANXA8L1 ANXA8	2.36e-03	13	102	2	404
GeneFamily	ATP binding cassette subfamily A	ABCA12 ABCA10	2.74e-03	14	102	2	805
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	STARD13 ARHGAP39 ARHGAP35	2.82e-03	50	102	3	721
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	STARD13 KDM5B ITSN1 APBB2 APC SPECC1L STIL ARHGAP35 MED1 PICALM EFR3A CEP350 ATP6V1H SIPA1L1 TUBGCP3 UTP20 ROCK1 PLCB4 ARAP2	2.00e-07	856	142	19	M4500
Coexpression	GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP	KDM5B AOAH CARS1 ARHGAP39 WAC DRG1 CEP350 UTP20 LY75	1.53e-06	200	142	9	M6558
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	GPR39 GAS6 APBB2 DENND3 PLA2R1 RBMS3 CTNND2 ARAP2	2.15e-07	189	146	8	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	facs-Skin-Anagen-24m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM5B CCDC73 ABCA12 CPNE5 SIPA1L1 LRP4 CYP4F22	1.35e-06	167	146	7	02c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR39 GAS6 APBB2 DENND3 RBMS3 CTNND2 ARAP2	2.14e-06	179	146	7	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	GPR39 SIPA1L3 ANXA8L1 APBB2 RBMS3 CTNND2 ARAP2	2.66e-06	185	146	7	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	GPR39 GAS6 APBB2 DENND3 RBMS3 CTNND2 ARAP2	2.85e-06	187	146	7	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHX2 VWF ZNF280D KRT85 KATNB1 ARHGAP39 TBC1D24	2.96e-06	188	146	7	c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ANKFY1 KATNB1 BRCC3 TGFBR1 TMEM267 VPS41 UTP20	3.28e-06	191	146	7	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPR39 GAS6 APBB2 DENND3 RBMS3 CTNND2 ARAP2	4.02e-06	197	146	7	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMED7 ZNF207 APLP2 HUWE1 VPS41 OSBPL9 ARAP2	4.16e-06	198	146	7	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMED7 ZNF207 APLP2 HUWE1 VPS41 OSBPL9 ARAP2	4.16e-06	198	146	7	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ANXA8L1 GAS6 APBB2 ANXA8 DENND3 RBMS3 CTNND2	4.30e-06	199	146	7	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	MS-CD4-CD8_2\|MS / Condition, Cell_class and T cell subcluster	ZBTB6 ZNF280D CES1 CARS1 PLA2R1 CYP4F22	9.87e-06	149	146	6	08fb6be5599c5988890c851ce5ac6781c319948e
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KDM5B ABCA12 ANXA8L1 GAS6 CCDC150 RBMS3	1.38e-05	158	146	6	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ABCA12 GPR39 PIWIL1 SLAMF1 NPY4R	1.54e-05	95	146	5	ffbf3e362384c87b9db690ed39cd215e1f68375c
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC12A6 RNF19A AOAH ZNF529 ERMARD ARAP2	2.02e-05	169	146	6	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	STARD13 ARHGAP39 INSC ASPA CTNND2 ARAP2	2.30e-05	173	146	6	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	AT1_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	RNF19A GAS6 APBB2 APC ANXA8 RBMS3	2.30e-05	173	146	6	b29816427428c7053017477f59b828bf1357f3b2
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	GPR39 APBB2 DENND3 RBMS3 CTNND2 ARAP2	2.38e-05	174	146	6	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	GAS6 APBB2 ANXA8 DENND3 RBMS3 CTNND2	2.54e-05	176	146	6	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	T_cells-GZMK+_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	STRBP AOAH ARHGAP35 DZIP3 EXOC2 ARAP2	2.79e-05	179	146	6	798f208014f2229c597934775646ddbbacf94b69
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	STARD13 GAS6 ANXA8 DENND3 RBMS3 CTNND2	3.16e-05	183	146	6	6821dca076318115d360ff426eb1218cfe104063
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPR39 APBB2 DENND3 RBMS3 CTNND2 ARAP2	3.25e-05	184	146	6	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPR39 APBB2 DENND3 RBMS3 CTNND2 ARAP2	3.25e-05	184	146	6	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR39 APBB2 DENND3 RBMS3 CTNND2 ARAP2	3.35e-05	185	146	6	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF APC APLP2 CEP350 PLCB4 IPO11	3.46e-05	186	146	6	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR39 APBB2 DENND3 RBMS3 CTNND2 ARAP2	3.56e-05	187	146	6	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	Control-Epithelial-ATI\|Epithelial / Disease state, Lineage and Cell class	ANXA8L1 GAS6 APBB2 ANXA8 DENND3 RBMS3	3.56e-05	187	146	6	3a032432f780525f4f4c2a358897d9989b1ecae7
ToppCell	AT1-AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ANXA8L1 GAS6 ANXA8 DENND3 RBMS3 CTNND2	3.67e-05	188	146	6	be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KIF21B SLC12A6 APBB2 GTDC1 ZNF529 BRAT1	3.78e-05	189	146	6	bccb3481ffed597c845fe860da658505316105b5
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-H_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABCA12 ANXA8L1 GAS6 ANXA8 ASPA LRP4	4.13e-05	192	146	6	7a6dd2ae217b8f8e460d47ad128904408299458c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 DNAH2 DZIP3 ULK4 ANKRD18A DNAH9	4.37e-05	194	146	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPR39 GAS6 APBB2 DENND3 RBMS3 CTNND2	4.50e-05	195	146	6	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	AT1_cells\|World / lung cells shred on cell class, cell subclass, sample id	ANXA8L1 GAS6 APBB2 ANXA8 DENND3 RBMS3	4.50e-05	195	146	6	792d6a49b0a875a00569071183d195287a9925c5
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 SIPA1L3 APBB2 SIPA1L1 SCAPER LRP4	4.63e-05	196	146	6	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	AT1_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	ANXA8L1 GAS6 APBB2 ANXA8 DENND3 RBMS3	4.76e-05	197	146	6	80d81be244c94c435accb643449b4ce6a3462c7f
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 GPR39 SIPA1L3 APBB2 SIPA1L1 SCAPER	4.90e-05	198	146	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Epithelial_cells-AT1-AT2_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ANXA8L1 GAS6 APBB2 ANXA8 DENND3 RBMS3	4.90e-05	198	146	6	fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	RNF19A STRBP CEP350 DZIP3 ROCK1 ANKRD18A	5.03e-05	199	146	6	61b1ed2db71b96157b92b7535d1955a4033098da
Disease	Syndactyly Cenani Lenz type	APC LRP4	2.30e-05	2	142	2	C1859309
Disease	secretory phospholipase A2 receptor measurement	PLA2R1 LY75	6.88e-05	3	142	2	EFO_0802043
Disease	microcephaly (implicated_via_orthology)	KATNB1 CARS1 STIL	4.89e-04	32	142	3	DOID:10907 (implicated_via_orthology)
Disease	response to clopidogrel, response to acetylsalicylate, major adverse cardiovascular event measurement	EFR3A WDR24	8.10e-04	9	142	2	EFO_0020863, GO_1903492, GO_1903493
Disease	Congenital Nonbullous Ichthyosiform Erythroderma	ABCA12 CYP4F22	1.23e-03	11	142	2	C0079154
Disease	Congenital ichthyosis of skin	ABCA12 CYP4F22	1.23e-03	11	142	2	cv:C0020758
Disease	mean reticulocyte volume	ITSN1 GAS6 C19orf47 DNAH2 SPECC1L TBC1D24 WAC CEP350 THADA LY75 IPO11	1.72e-03	799	142	11	EFO_0010701
Disease	retinal drusen	VWF PTK2B CTNND2	1.92e-03	51	142	3	EFO_1001155
Disease	nausea and vomiting of pregnancy severity measurement	GFRAL SPECC1L	2.01e-03	14	142	2	EFO_0009265
Disease	dental caries	EPHX2 APBB2 CCDC150 RBMS3 EXOC2	2.16e-03	187	142	5	EFO_0003819
Disease	Alzheimer disease, family history of Alzheimer’s disease	EPHX2 PICALM PTK2B UNC5CL	2.66e-03	119	142	4	EFO_0009268, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
THTCQVVMQKVSVCI	ZNF280D	716	Q6N043
VVMQKVSVCIPTSEH	ZNF280D	721	Q6N043
TTTSAVMVHCLRQKT	CES1	276	P23141
QKIMDHVEESLCSAA	BRAT1	196	Q6PJG6
RHCKTNLVTASMEAI	ACOT7L	186	Q6ZUV0
AIATSLHEICSKIMA	APBB2	536	Q92870
MKAVHSQEEACAIVL	ANKRD18A	106	Q8IVF6
TALMVACITKHVDQQ	ANKRD34C	46	P0C6C1
KVVHRQDMCKAATES	C19orf47	106	Q8N9M1
HRNEMCDTEKITSLI	ABCA10	626	Q8WWZ4
HETTFNSIMKCDVDI	ACTBL2	276	Q562R1
VQNKCSVILTSHSME	ABCA12	2436	Q86UK0
VSVACLTERIHQMEE	SPECC1L	391	Q69YQ0
IATSLHEICSKIMAE	APBB1	491	O00213
VDSSLKERASMVAHC	ARAP2	1601	Q8WZ64
AVARAVCKATTHEVM	SNAP91	21	O60641
IDCQVMDTRILHIKS	ATF6	616	P18850
MVTLHSDKESEEVCH	ADCY10	781	Q96PN6
KELVAHMDTVRTLCS	DENND3	1161	A2RUS2
NAEVAIVCKVMAEHV	ATP4B	256	P51164
TAVCCTLHEVITKNM	CTNND2	961	Q9UQB3
AFCQHVSKVIEIRTM	EFR3A	616	Q14156
LTTIKCMQTIKASEH	ANKRD37	116	Q7Z713
MKRVNSCVKSDEHVL	RBM41	1	Q96IZ5
RMESTEKCEVVIQHF	RBMS3	186	Q6XE24
TEILTMTCIAVERHQ	QRFPR	131	Q96P65
MIVTSDRHVKKEACE	ARHGAP39	731	Q9C0H5
THTTKMESIQVLEEC	RGS17	56	Q9UGC6
ICITNAKSDSHVRML	INTS13	161	Q9NVM9
ETTNSMVESIKHCIV	OSBPL9	161	Q96SU4
TMSDKEITHDVKAVC	APLP2	296	Q06481
EITHDVKAVCSQEAM	APLP2	301	Q06481
EEAMLTVVKCTQNLH	ANXA8	241	P13928
KLLSADMNADVVCHT	AOAH	96	P28039
IATTLVSHKADVDMV	ANKFY1	271	Q9P2R3
EHEVILSSMIKECEQ	RELCH	1151	Q9P260
KEVTDHMVSLACSDI	GPR39	66	O43194
TTVEDFCMKIHKNLI	DRG1	316	Q9Y295
DTKSQCHVSLDMVHL	NRAP	866	Q86VF7
SEHCQDSVDVMVFIV	NPY4R	31	P50391
VLQAHISDTSVIVKM	KRT85	266	P78386
CHLTQENEIKVMSTV	LRRC53	356	A6NM62
VTECDTKMHVLHVLS	IPO11	571	Q9UI26
SHDDIVTRMKNIECI	KAT5	221	Q92993
DTMCVVLTSRHKNLD	KATNB1	496	Q9BVA0
NEIMSIISKHEICII	FSIP2	4831	Q5CZC0
DTNLCAIHAKRVTIM	H3-5	106	Q6NXT2
FHCKRIDVITMQTLV	GPR26	201	Q8NDV2
CVMATLQHTAEEIKR	EXOC2	586	Q96KP1
RKAVATCSSHMVVVS	OR2T7	226	P0C7T2
EAKNKAMSTCITHII	OR4N2	231	Q8NGD1
VMCLTVTQTASQHDL	KIF21B	1456	O75037
MATTQDEVHTKCQKL	LY75	1266	O60449
HVIRTLKMECSETHV	LRRC37B	821	Q96QE4
HTIRILMCQKTELET	GOLGA6L7	91	A0A1B0GV03
VCHDQTPTTKMIAVT	TUBGCP3	496	Q96CW5
VMEQSVLAHITADIC	KDM5B	466	Q9UGL1
DCHISKMIELSKVVD	LRIT3	206	Q3SXY7
KAVATCSSHMVVVSL	OR2T27	236	Q8NH04
TTVMKQHVCSLLVGV	OR4C13	131	Q8NGP0
TEVKSALRHMVLENC	OR2C3	296	Q8N628
MSSKHRICSQEEVVI	MROH8	1	Q9H579
EKHARLQAVMCIIST	HUWE1	2171	Q7Z6Z7
KVLDAESMHDCVSVV	HUWE1	2656	Q7Z6Z7
ESMHDCVSVVKVSIV	HUWE1	2661	Q7Z6Z7
EVLMDCAHLVKANSI	CCDC25	66	Q86WR0
TEKECLNQLARVTHM	DZIP3	881	Q86Y13
ETHVSCCVMVKNIER	POLA1	371	P09884
KLSCSSHFVKEITVM	OR1L1	236	Q8NH94
HTTFCEKVVVLMNID	DYNC2H1	696	Q8NCM8
HLESLAESVCMTVQT	HDAC10	306	Q969S8
ASDESVLSMHKVCEA	EPHX2	411	P34913
EEAMLTVVKCTQNLH	ANXA8L1	241	Q5VT79
CKVTIMLENVLASHS	CCDC150	681	Q8NCX0
VQEMLRTQSVACIKH	COG1	566	Q8WTW3
SKEALHSKTCAVNMV	GFRAL	201	Q6UXV0
ITQSEESLCKIFQHM	GFRAL	296	Q6UXV0
AVEHTALALMEIKVC	GAS6	556	Q14393
CEVTMGSQCHITKTI	ITSN1	1621	Q15811
DVKTAVHMKTCTETE	CCDC73	791	Q6ZRK6
ITIAQAMIFCHTRKT	DDX19B	331	Q9UMR2
HSILTEEMICSQELE	CEP350	1971	Q5VT06
VTCISKVRSIQMIVH	IL22RA1	126	Q8N6P7
EHVLKSMKACVSETL	INSC	206	Q1MX18
TEVIKCRNEIMHSSE	CXorf38	156	Q8TB03
ETNACHSLITKMTDE	ERMARD	471	Q5T6L9
GDRQKIMTICTIDVH	DNAH9	1771	Q9NYC9
IIVKCEMGHNSTVEI	CUZD1	361	Q86UP6
ECKRQMLTASHTLAV	PTK2B	971	Q14289
LRHSEATEVSVCQEM	GRIK4	831	Q16099
QVLCMADVVISTAKH	GTDC1	356	Q4AE62
QSLIHCNITSVVKMT	HSD17B3	151	P37058
FITECRIHASKVQMI	DNAH2	726	Q9P225
HIDVCSKTKEINNMT	SLC12A6	386	Q9UHW9
SAVHIDTECVSVMLQ	SCAPER	371	Q9BY12
EKQLHMELASRVCVV	POLRMT	401	O00411
EHISLMTLDSLQKCV	CYP4F22	201	Q6NT55
TFTICHKTEVMKNTL	CPNE5	211	Q9HCH3
SLVCVVMDVQDSTHV	MED1	461	Q15648
SIHEAMEQQTISVAK	MCM9	426	Q9NXL9
NSIMLCTDVSHKVLR	PIWIL1	261	Q96J94
MLKHENITTAATEII	UTP20	1626	O75691
MCTLVSLSVEHEEAQ	STARD13	1026	Q9Y3M8
TFINLMTHICKEQTV	ATP6V1H	76	Q9UI12
LASKVISHHMQTCVE	THADA	1656	Q6YHU6
QHIKSMVLREVTECN	SLC6A16	451	Q9GZN6
IHKALCDNVDTRTVM	CARS1	501	P49589
STMQKLHCTQVDKIV	PLCB4	951	Q15147
AVMSVHSAVKEESAC	PWWP3B	216	Q5H9M0
RVHISSCLKVQEQMA	RNF166	111	Q96A37
VALACSDTHVKELML	OR5AL1	201	P0C617
HIVVTMAKSLENSVE	SLAMF1	61	Q13291
EICKVAVATLSHEQM	SIPA1L1	996	O43166
CKVAVVTLTHDQMID	SIPA1L3	1011	O60292
VQNMVSTVECALKHV	STRBP	31	Q96SI9
IHMSEICTELKNLRS	WAC	596	Q9BTA9
TSLLLEKDQSTCHME	STAG3L1	181	P0CL83
CVECKMHIVEQTEFI	ARHGAP35	86	Q9NRY4
TIHKIKCVCDSQMSV	SYT14P1	16	Q58G82
TCLMHKAQLVSITDQ	PLA2R1	1141	Q13018
KTRVVVTMQHCTKDN	OXCT2	431	Q9BYC2
CMQVCKIHSEVVEDT	SDSL	241	Q96GA7
TTDKVIHNSMCIAEI	TGFBR1	61	P36897
VCLNHALSTEKEEVM	BRCC3	21	P46736
MTSCHIAEEHIQKVA	ASPA	1	P45381
QIAKVMEEVSAIHTS	APC	886	P25054
ECEVMDTRVIHIKTS	ATF6B	646	Q99941
AVSKTVCKATTHEIM	PICALM	21	Q13492
CQAAHKLMVAVSEDV	TBC1D24	191	Q9ULP9
CKVHTQELCSREMIV	STIL	126	Q15468
MEAQHVTLCLTEAVT	ZNF143	21	P52747
CMKSIEVKHSALSVE	VWF	2001	P04275
QTCTTKSLAMDKVAH	MKS1	356	Q9NXB0
IASIESIHSEMCTDK	RNF19A	91	Q9NV58
ALTQMESACVTIHEA	TMED3	136	Q9Y3Q3
QMESACVSIHEALKS	TMED7	146	Q9Y3B3
DCSALTNEIIVTMHT	UNC5CL	356	Q8IV45
HSVCTLSKMLEILEQ	UMPS	171	P11172
SEHCQDSVDVMVFIV	NPY4R2	31	P0DQD5
EILQKDAASCMTVHD	VPS41	41	P49754
MAVCEIKVHSADNTR	PLEKHA3	46	Q9HB20
KHQSIEEAKSVAMCE	ROCK1	701	Q13464
AIHCMQVHKETIDAV	ZNF207	51	O43670
QKIHSEERLVCSMNV	ZNF548	496	Q8NEK5
MHCEKVFRISSQLIE	ZNF529	341	Q6P280
RAKEMHCVQTIASVA	WDR24	241	Q96S15
ESKESVSHVQLACSM	WDR27	26	A2RRH5
HITEEELKTLMECVS	TRMT10C	111	Q7L0Y3
MASETEKTHALLQTC	TMEM267	1	Q0VDI3
VNHMAAKIIENVCTT	ULK4	621	Q96C45
QMVHIVEKCTEALSK	ZBTB6	111	Q15916
TCDVHIRKQQMVSVE	KLHL42	376	Q9P2K6
LLRDHVCMKTDTVSI	LRP4	1836	O75096