Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalmodulin binding

PDE1C SLC8A3 MYH9 ARPP21 MYO5C

1.31e-04230435GO:0005516
GeneOntologyMolecularFunctionAP-2 adaptor complex binding

RAB38 FCHO1

4.05e-0414432GO:0035612
GeneOntologyMolecularFunction3',5'-cyclic-AMP phosphodiesterase activity

PDE1C PDE6A

1.02e-0322432GO:0004115
GeneOntologyMolecularFunction3',5'-cyclic-GMP phosphodiesterase activity

PDE1C PDE6A

1.21e-0324432GO:0047555
GeneOntologyMolecularFunction3',5'-cyclic-nucleotide phosphodiesterase activity

PDE1C PDE6A

1.32e-0325432GO:0004114
GeneOntologyMolecularFunctioncAMP binding

PDE1C RAPGEF4

1.32e-0325432GO:0030552
GeneOntologyMolecularFunctioncyclic-nucleotide phosphodiesterase activity

PDE1C PDE6A

1.54e-0327432GO:0004112
GeneOntologyBiologicalProcessprotein-containing complex localization

IFT140 SFPQ MAK HAP1 RAB8A RAPGEF4

1.98e-05278426GO:0031503
GeneOntologyCellularComponentnon-motile cilium

IFT140 DRD2 MAK PDE6A RAB8A RAPGEF4

2.87e-06196436GO:0097730
GeneOntologyCellularComponentphotoreceptor outer segment

IFT140 MAK PDE6A RAPGEF4

7.92e-05111434GO:0001750
GeneOntologyCellularComponentneuron projection terminus

VTI1A SLC8A3 DRD2 HAP1 RAPGEF4

1.12e-04233435GO:0044306
GeneOntologyCellularComponentdendritic spine

SLC8A3 DRD2 HAP1 RAB8A RAPGEF4

1.34e-04242435GO:0043197
GeneOntologyCellularComponentneuron spine

SLC8A3 DRD2 HAP1 RAB8A RAPGEF4

1.48e-04247435GO:0044309
GeneOntologyCellularComponentphotoreceptor cell cilium

IFT140 MAK PDE6A RAPGEF4

1.89e-04139434GO:0097733
GeneOntologyCellularComponent9+0 non-motile cilium

IFT140 MAK PDE6A RAPGEF4

2.73e-04153434GO:0097731
GeneOntologyCellularComponentphagocytic vesicle

RAB38 MYH9 RAB8B RAB8A

3.01e-04157434GO:0045335
GeneOntologyCellularComponentGABA-ergic synapse

GABRG3 MDGA2 DRD2 HAP1

3.55e-04164434GO:0098982
GeneOntologyCellularComponentsynaptic vesicle

VTI1A DRD2 HAP1 RAB8B RAB8A

3.63e-04300435GO:0008021
GeneOntologyCellularComponentpresynapse

VTI1A SLC8A3 DRD2 HAP1 SLC1A6 RAB8B RAB8A RAPGEF4

3.91e-04886438GO:0098793
GeneOntologyCellularComponentexocytic vesicle

VTI1A DRD2 HAP1 RAB8B RAB8A

4.87e-04320435GO:0070382
GeneOntologyCellularComponentphagocytic vesicle membrane

RAB38 RAB8B RAB8A

6.64e-0483433GO:0030670
GeneOntologyCellularComponentsomatodendritic compartment

GABRG3 VTI1A PDE1C SLC8A3 DRD2 SFPQ HAP1 RAB8A RAPGEF4

7.43e-041228439GO:0036477
GeneOntologyCellularComponentaxon terminus

SLC8A3 DRD2 HAP1 RAPGEF4

8.99e-04210434GO:0043679
GeneOntologyCellularComponentciliary membrane

DRD2 PDE6A RAB8A

1.08e-0398433GO:0060170
GeneOntologyCellularComponentendocytic vesicle

RAB38 MYH9 DRD2 RAB8B RAB8A

1.11e-03384435GO:0030139
GeneOntologyCellularComponentclathrin-coated vesicle

VTI1A FCHO1 RAB8B RAB8A

1.41e-03237434GO:0030136
GeneOntologyCellularComponentdendrite

GABRG3 SLC8A3 DRD2 SFPQ HAP1 RAB8A RAPGEF4

1.70e-03858437GO:0030425
GeneOntologyCellularComponentdendritic tree

GABRG3 SLC8A3 DRD2 SFPQ HAP1 RAB8A RAPGEF4

1.72e-03860437GO:0097447
GeneOntologyCellularComponentcilium

IFT140 PDE1C DRD2 MAK PDE6A RAB8A RAPGEF4

2.20e-03898437GO:0005929
GeneOntologyCellularComponentcell body

RAB38 VTI1A PDE1C SLC8A3 DRD2 RAB8A RAPGEF4

2.66e-03929437GO:0044297
GeneOntologyCellularComponenttrans-Golgi network transport vesicle

RAB8B RAB8A

3.07e-0340432GO:0030140
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

IFT140 SFPQ MAK HAP1

4.02e-03317434GO:0032838
GeneOntologyCellularComponenttransport vesicle

VTI1A DRD2 HAP1 RAB8B RAB8A

4.09e-03519435GO:0030133
GeneOntologyCellularComponentphotoreceptor connecting cilium

IFT140 MAK

4.39e-0348432GO:0032391
GeneOntologyCellularComponentpostsynapse

GABRG3 SLC8A3 DRD2 HAP1 SLC1A6 RAB8A RAPGEF4

4.41e-031018437GO:0098794
GeneOntologyCellularComponentmicrobody

ABCD3 VWA8 RAB8B

4.49e-03162433GO:0042579
GeneOntologyCellularComponentperoxisome

ABCD3 VWA8 RAB8B

4.49e-03162433GO:0005777
GeneOntologyCellularComponentcentriole

IFT140 HAP1 RAB8A

5.31e-03172433GO:0005814
GeneOntologyCellularComponentcoated vesicle

VTI1A FCHO1 RAB8B RAB8A

6.29e-03360434GO:0030135
GeneOntologyCellularComponentcytoplasmic region

IFT140 SFPQ MAK HAP1

6.29e-03360434GO:0099568
GeneOntologyCellularComponentmyosin complex

MYH9 MYO5C

6.57e-0359432GO:0016459
GeneOntologyCellularComponentneuronal cell body

VTI1A PDE1C SLC8A3 DRD2 RAB8A RAPGEF4

6.89e-03835436GO:0043025
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

VTI1A RAPGEF4

8.40e-0367432GO:0098686
GeneOntologyCellularComponentmicrobody membrane

ABCD3 RAB8B

8.89e-0369432GO:0031903
GeneOntologyCellularComponentperoxisomal membrane

ABCD3 RAB8B

8.89e-0369432GO:0005778
GeneOntologyCellularComponentendosome

RAB38 VTI1A MYH9 STAMBPL1 HAP1 RAB8B RAB8A

9.17e-031167437GO:0005768
GeneOntologyCellularComponentendocytic vesicle membrane

RAB38 RAB8B RAB8A

9.42e-03212433GO:0030666
GeneOntologyCellularComponentpostsynaptic membrane

GABRG3 SLC8A3 DRD2 SLC1A6

9.44e-03405434GO:0045211
DomainR3H

ARPP21 NKRF

1.76e-049422SM00393
DomainR3H

ARPP21 NKRF

2.68e-0411422PS51061
DomainR3H

ARPP21 NKRF

2.68e-0411422PF01424
DomainR3H_dom

ARPP21 NKRF

2.68e-0411422IPR001374
Domain-

ARPP21 NKRF

2.68e-04114223.30.1370.50
DomainMyosin_N

MYH9 MYO5C

5.09e-0415422IPR004009
DomainMyosin_N

MYH9 MYO5C

5.09e-0415422PF02736
DomainRAB

RAB38 RAB8B RAB8A

5.89e-0473423PS51419
DomainPDEase

PDE1C PDE6A

8.24e-0419422IPR023088
DomainMyosin-like_IQ_dom

MYH9 MYO5C

8.24e-0419422IPR027401
Domain-

MYH9 MYO5C

8.24e-04194224.10.270.10
DomainPDEase_I

PDE1C PDE6A

1.01e-0321422PF00233
DomainPDEASE_I

PDE1C PDE6A

1.01e-0321422PS00126
DomainPDEase_CS

PDE1C PDE6A

1.01e-0321422IPR023174
Domain-

PDE1C PDE6A

1.11e-03224221.10.1300.10
DomainPDEase_catalytic_dom

PDE1C PDE6A

1.21e-0323422IPR002073
DomainHDc

PDE1C PDE6A

1.32e-0324422SM00471
DomainHD/PDEase_dom

PDE1C PDE6A

1.32e-0324422IPR003607
Domain7TM_GPCR_Srsx

TAAR2 DRD2 MLNR

2.03e-03112423SM01381
DomainP-loop_NTPase

ABCD3 RAB38 MYH9 VWA8 RAB8B MYO5C RAB8A

2.61e-03848427IPR027417
DomainMYOSIN_MOTOR

MYH9 MYO5C

3.30e-0338422PS51456
DomainMyosin_head

MYH9 MYO5C

3.30e-0338422PF00063
DomainMyosin_head_motor_dom

MYH9 MYO5C

3.30e-0338422IPR001609
DomainMYSc

MYH9 MYO5C

3.30e-0338422SM00242
DomainRas

RAB38 RAB8B RAB8A

3.52e-03136423PF00071
DomainSmall_GTPase

RAB38 RAB8B RAB8A

5.55e-03160423IPR001806
DomainSmall_GTP-bd_dom

RAB38 RAB8B RAB8A

6.24e-03167423IPR005225
DomainIQ

MYH9 MYO5C

1.11e-0271422PF00612
Pubmed

Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.

RAB38 RAB8B RAB8A

1.42e-061843321255211
Pubmed

A DRD2 and ANKK1 haplotype is associated with nicotine dependence.

ANKK1 DRD2

1.49e-06243222382052
Pubmed

Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: a replication and extension study.

ANKK1 DRD2

1.49e-06243218698520
Pubmed

Meta-analysis of two dopamine D2 receptor gene polymorphisms with tardive dyskinesia in schizophrenia patients.

ANKK1 DRD2

1.49e-06243217767146
Pubmed

Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions.

ANKK1 DRD2

1.49e-06243225139281
Pubmed

Association between DRD2/ANKK1 TaqIA Polymorphism and Susceptibility with Tourette Syndrome: A Meta-Analysis.

ANKK1 DRD2

1.49e-06243226110876
Pubmed

Associations of the ANKK1 and DRD2 gene polymorphisms with overweight, obesity and hedonic hunger among women from the Northwest of Iran.

ANKK1 DRD2

1.49e-06243232020513
Pubmed

DRD2 and ANKK1 gene polymorphisms and alcohol dependence: a case-control study among a Mendelian population of East Asian ancestry.

ANKK1 DRD2

1.49e-06243223443985
Pubmed

Support for an association of the C939T polymorphism in the human DRD2 gene with tardive dyskinesia in schizophrenia.

ANKK1 DRD2

1.49e-06243217669630
Pubmed

Alcohol misuse in emerging adulthood: Association of dopamine and serotonin receptor genes with impulsivity-related cognition.

ANKK1 DRD2

1.49e-06243227399274
Pubmed

Lack of association in Japanese patients between neuroleptic malignant syndrome and the TaqI A polymorphism of the dopamine D2 receptor gene.

ANKK1 DRD2

1.49e-06243212605103
Pubmed

Relationship between functional dopamine D2 and D3 receptors gene polymorphisms and neuroleptic malignant syndrome.

ANKK1 DRD2

1.49e-06243212555236
Pubmed

Variation in DRD2 dopamine gene predicts Extraverted personality.

ANKK1 DRD2

1.49e-06243219897017
Pubmed

Double dissociation of dopamine genes and timing in humans.

ANKK1 DRD2

1.49e-06243221261454
Pubmed

Analysis of ANKKI (rs1800497) and DRD2 (rs1079597, rs1800498) variants in five ethnic groups from Punjab, North-West India.

ANKK1 DRD2

1.49e-06243226970175
Pubmed

DRD2 and ANKK1 genotype in alcohol-dependent patients with psychopathic traits: association and interaction study.

ANKK1 DRD2

1.49e-06243218669994
Pubmed

Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: analysis of pooled data from two clinical trials.

ANKK1 DRD2

1.49e-06243218058343
Pubmed

Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution.

ANKK1 DRD2

1.49e-06243219373123
Pubmed

DRD2/ANKK1 TaqI polymorphism and smoking behavior of Egyptian male cigarette smokers.

ANKK1 DRD2

1.49e-06243218058350
Pubmed

A large-scale meta-analysis of the association between the ANKK1/DRD2 Taq1A polymorphism and alcohol dependence.

ANKK1 DRD2

1.49e-06243223203481
Pubmed

The association between DRD2/ANKK1 and genetically informed measures of alcohol use and problems.

ANKK1 DRD2

1.49e-06243222970887
Pubmed

The association of DRD2 -141C and ANKK1 TaqIA polymorphisms with alcohol dependence in Korean population classified by the Lesch typology.

ANKK1 DRD2

1.49e-06243223558112
Pubmed

DRD2 and ANKK1 genes associate with late-onset heroin dependence in men.

ANKK1 DRD2

1.49e-06243228854834
Pubmed

Impulsivity and genetic variants in DRD2 and ANKK1 moderate longitudinal associations between sleep problems and overweight from ages 5 to 11.

ANKK1 DRD2

1.49e-06243223828101
Pubmed

Influences of a DRD2 polymorphism on updating of long-term memory representations and caudate BOLD activity: magnification in aging.

ANKK1 DRD2

1.49e-06243225486867
Pubmed

Analysis of the linkage of the Taq1A and Taq1B loci of the dopamine D2 receptor gene with schizophrenia in patients and their siblings.

ANKK1 DRD2

1.49e-06243212762588
Pubmed

The effect of the ANKK1/DRD2 Taq1A polymorphism on weight changes of dopaminergic treatment in prolactinomas.

ANKK1 DRD2

1.49e-06243223740147
Pubmed

Association between DRD2/ANKK1 Taq1A genotypes, depression and smoking cessation with nicotine replacement therapy.

ANKK1 DRD2

1.49e-06243221540761
Pubmed

Association between DRD2/ANKK1 TaqIA polymorphism and common illicit drug dependence: evidence from a meta-analysis.

ANKK1 DRD2

1.49e-06243225500252
Pubmed

Superior cognitive goal maintenance in carriers of genetic markers linked to reduced striatal D2 receptor density (C957T and DRD2/ANKK1-TaqIA).

ANKK1 DRD2

1.49e-06243230125286
Pubmed

Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region.

ANKK1 DRD2

1.49e-06243233524518
Pubmed

Dopamine D2 receptor and ankyrin repeat and kinase domain containing 1 genes among the two linguistically distinct tribal populations of Ranchi district, Jharkhand, India.

ANKK1 DRD2

1.49e-06243223590110
Pubmed

The DRD2 TaqI-B polymorphism and its relationship to smoking abstinence and withdrawal symptoms.

ANKK1 DRD2

1.49e-06243217189962
Pubmed

Influence of ANKK1 and DRD2 polymorphisms in response to haloperidol.

ANKK1 DRD2

1.49e-06243222893251
Pubmed

Genetic and Epigenetic Analysis Revealing Variants in the NCAM1-TTC12-ANKK1-DRD2 Cluster Associated Significantly With Nicotine Dependence in Chinese Han Smokers.

ANKK1 DRD2

1.49e-06243231867628
Pubmed

Sexually dimorphic link between dopamine D2 receptor gene and neuroticism-anxiety.

ANKK1 DRD2

1.49e-06243215812318
Pubmed

DRD2/ANKK1 TaqI A genotype moderates the relationship between alexithymia and the relative value of alcohol among male college binge drinkers.

ANKK1 DRD2

1.49e-06243222728571
Pubmed

A prospective study of the effects of the DRD2/ANKK1 TaqIA polymorphism and impulsivity on smoking initiation.

ANKK1 DRD2

1.49e-06243223153044
Pubmed

DRD2/ANKK1 TaqI A polymorphism affects corticostriatal activity in response to negative affective facial stimuli.

ANKK1 DRD2

1.49e-06243221510979
Pubmed

Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias.

ANKK1 DRD2

1.49e-06243217453061
Pubmed

Impulsivity-related cognition in alcohol dependence: Is it moderated by DRD2/ANKK1 gene status and executive dysfunction?

ANKK1 DRD2

1.49e-06243224629326
Pubmed

[DRD2/ANKK1 Taq IA polymorphism and early infant temperament].

ANKK1 DRD2

1.49e-06243220199723
Pubmed

Myosin Vc, a member of the actin motor family associated with Rab8, is involved in the release of DV2 from HepG2 cells.

MYO5C RAB8A

1.49e-06243219641326
Pubmed

High frequency of the DRD2/ANKK1 A1 allele in Mexican Native Amerindians and Mestizos and its association with alcohol consumption.

ANKK1 DRD2

1.49e-06243228152448
Pubmed

Significant association of DRD2 and ANKK1 genes with rural heroin dependence and relapse in men.

ANKK1 DRD2

1.49e-06243232588604
Pubmed

Effects of DRD2/ANKK1 gene variations and clinical factors on aripiprazole efficacy in schizophrenic patients.

ANKK1 DRD2

1.49e-06243218926547
Pubmed

Dopamine DRD2 polymorphism alters reversal learning and associated neural activity.

ANKK1 DRD2

1.49e-06243219321766
Pubmed

Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele.

ANKK1 DRD2

1.49e-06243218927395
Pubmed

Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.

ANKK1 DRD2

1.49e-06243219512960
Pubmed

Test of association between TaqIA A1 allele and alcohol use disorder phenotypes in a sample of adolescent patients with serious substance and behavioral problems.

ANKK1 DRD2

1.49e-06243217069991
Pubmed

Temporomandibular disorder in construction workers associated with ANKK1 and DRD2 genes.

ANKK1 DRD2

1.49e-06243236043564
Pubmed

IDRD2 TaqIA polymorphism is associated with urinary homovanillic acid levels in a sample of Spanish male alcoholic patients.

ANKK1 DRD2

1.49e-06243215545020
Pubmed

DRD2/ANKK1 polymorphism modulates the effect of ventral striatal activation on working memory performance.

ANKK1 DRD2

1.49e-06243224713612
Pubmed

DRD2/ANKK1 Taq1A (rs 1800497 C>T) genotypes are associated with susceptibility to second generation antipsychotic-induced akathisia.

ANKK1 DRD2

1.49e-06243223118020
Pubmed

The effect of selected polymorphisms of the dopamine receptor gene DRD2 and the ANKK-1 on the preference of concentrations of sucrose solutions in men with alcohol dependence.

ANKK1 DRD2

1.49e-06243224247049
Pubmed

DRD2/ANKK1 TaqI A1 polymorphism associates with overconsumption of unhealthy foods and biochemical abnormalities in a Mexican population.

ANKK1 DRD2

1.49e-06243230353454
Pubmed

The 3' region of the DRD2 gene is involved in genetic susceptibility to schizophrenia.

ANKK1 DRD2

1.49e-06243214741327
Pubmed

A genetic schizophrenia-susceptibility region located between the ANKK1 and DRD2 genes.

ANKK1 DRD2

1.49e-06243220138949
Pubmed

A pilot study of genetic variants in dopamine regulators with indoor tanning and melanoma.

ANKK1 DRD2

1.49e-06243223947671
Pubmed

A polymorphism of DRD2 gene and brain atrophy in methamphetamine psychosis.

ANKK1 DRD2

1.49e-06243215542731
Pubmed

Between- and within-family association test of the dopamine receptor D2 TaqIA polymorphism and alcohol abuse and dependence in a general population sample of adults.

ANKK1 DRD2

1.49e-06243217446975
Pubmed

The significant association of Taq1A genotypes in DRD2/ANKK1 with smoking cessation in a large-scale meta-analysis of Caucasian populations.

ANKK1 DRD2

1.49e-06243226624925
Pubmed

Investigating the association between common DRD2/ANKK1 genetic polymorphisms and schizophrenia: a meta-analysis.

ANKK1 DRD2

1.49e-06243234470923
Pubmed

Suicidal behavior and haplotypes of the dopamine receptor gene (DRD2) and ANKK1 gene polymorphisms in patients with alcohol dependence--preliminary report.

ANKK1 DRD2

1.49e-06243225415204
Pubmed

Posttraumatic Brain Injury Cognitive Performance Is Moderated by Variation Within ANKK1 and DRD2 Genes.

ANKK1 DRD2

1.49e-06243225931179
Pubmed

Interactions between DRD2/ANKK1 TaqIA Polymorphism and Dietary Factors Influence Plasma Triglyceride Concentrations in Diabetic Patients from Western Mexico: A Cross-sectional Study.

ANKK1 DRD2

1.49e-06243231766642
Pubmed

Analysis of Selected Variants of DRD2 and ANKK1 Genes in Combat Athletes.

ANKK1 DRD2

1.49e-06243234440413
Pubmed

Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.

ANKK1 DRD2

1.49e-06243217850642
Pubmed

An affected pedigree member analysis of linkage between the dopamine D2 receptor gene TaqI polymorphism and obesity and hypertension.

ANKK1 DRD2

1.49e-06243215939106
Pubmed

Dopamine DRD2 Taq I polymorphism associates with caudate nucleus volume and cognitive performance in memory impaired subjects.

ANKK1 DRD2

1.49e-06243212151753
Pubmed

Association study of dopamine receptor D2 TaqI A polymorphism and reward-related personality traits in healthy Korean young females.

ANKK1 DRD2

1.49e-06243218259088
Pubmed

Genotypes of ANKK1 and DRD2 genes and risk of metabolic syndrome and its components: A cross-sectional study on Iranian women.

ANKK1 DRD2

1.49e-06243234420901
Pubmed

Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African-American sample.

ANKK1 DRD2

1.49e-06243218354387
Pubmed

Associations of prenatal nicotine exposure and the dopamine related genes ANKK1 and DRD2 to verbal language.

ANKK1 DRD2

1.49e-06243223691092
Pubmed

The ANKK1/DRD2 locus is a genomic substrate for affective priming and recognition of angry faces.

ANKK1 DRD2

1.49e-06243226664790
Pubmed

The D2 dopamine receptor gene variant C957T affects human fear conditioning and aversive priming.

ANKK1 DRD2

1.49e-06243219900188
Pubmed

A 35.8 kilobases haplotype spanning ANKK1 and DRD2 is associated with heroin dependence in Han Chinese males.

ANKK1 DRD2

1.49e-06243229550268
Pubmed

The Addiction-Susceptibility TaqIA/Ankk1 Controls Reward and Metabolism Through D2 Receptor-Expressing Neurons.

ANKK1 DRD2

1.49e-06243236805080
Pubmed

The influence of the dopaminergic system on cognitive functioning: A molecular genetic approach.

ANKK1 DRD2

4.48e-06343216026865
Pubmed

Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence.

ANKK1 DRD2

4.48e-06343223840506
Pubmed

COMT and DRD2/ANKK-1 gene-gene interaction account for resetting of gamma neural oscillations to auditory stimulus-driven attention.

ANKK1 DRD2

4.48e-06343228222164
Pubmed

Differential effects of 5-HTTLPR and DRD2/ANKK1 polymorphisms on electrocortical measures of error and feedback processing in children.

ANKK1 DRD2

4.48e-06343219046929
Pubmed

Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer.

RAB8B RAB8A

4.48e-06343231707148
Pubmed

Identification of a novel ANKK1 and other dopaminergic (DRD2 and DBH) gene variants in migraine susceptibility.

ANKK1 DRD2

4.48e-06343222875483
Pubmed

Epistatic effect of Ankyrin repeat and kinase domain containing 1 - Dopamine receptor D2 and catechol-o-methyltransferase single nucleotide polymorphisms on the risk for hazardous use of alcohol in Lithuanian population.

ANKK1 DRD2

4.48e-06343232889058
Pubmed

Association study of the SLC6A3 VNTR (DAT) and DRD2/ANKK1 Taq1A polymorphisms with alcohol dependence in a population from northeastern Brazil.

ANKK1 DRD2

4.48e-06343225684044
Pubmed

Prevalence of polymorphisms in the ANKK1, DRD2, DRD3 genes and metabolic syndrome in refractory schizophrenia.

ANKK1 DRD2

4.48e-06343229791666
Pubmed

Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomes.

RAB38 MYO5C

4.48e-06343225324551
Pubmed

A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response.

ANKK1 DRD2

4.48e-06343230104163
Pubmed

Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.

ANKK1 DRD2

4.48e-06343222967772
Pubmed

Contributions of the DAT1 and DRD2 genes to serious and violent delinquency among adolescents and young adults.

ANKK1 DRD2

4.48e-06343217120049
Pubmed

Effects of dopamine-related gene-gene interactions on working memory component processes.

ANKK1 DRD2

4.48e-06343219291230
Pubmed

Epistasis of the DRD2/ANKK1 Taq Ia and the BDNF Val66Met polymorphism impacts novelty seeking and harm avoidance.

ANKK1 DRD2

4.48e-06343220410875
Pubmed

Interaction between ALDH2*1*1 and DRD2/ANKK1 TaqI A1A1 genes may be associated with antisocial personality disorder not co-morbid with alcoholism.

ANKK1 DRD2

4.48e-06343221070510
Pubmed

A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.

RAB8B RAB8A

4.48e-06343212221131
Pubmed

The ANKK1/DRD2 gene TaqIA polymorphism (rs1800497) is associated with the severity of extrapyramidal side effects of haloperidol treatment in CYP2D6 extensive metabolizers with schizophrenia spectrum disorders.

ANKK1 DRD2

4.48e-06343236437548
Pubmed

Polymorphisms in the DBH and DRD2 gene regions and smoking behavior.

ANKK1 DRD2

4.48e-06343216032443
Pubmed

The ALDH2 and DRD2/ANKK1 genes interacted in bipolar II but not bipolar I disorder.

ANKK1 DRD2

4.48e-06343220577142
Pubmed

Elevated postmortem striatal t-DARPP expression in schizophrenia and associations with DRD2/ANKK1 polymorphism.

ANKK1 DRD2

4.48e-06343224704945
Pubmed

Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.

RAB8B RAB8A

4.48e-06343228076793
InteractionSCP2 interactions

SFPQ VWA8 MYO5C RAB8A

1.35e-0570424int:SCP2
GeneFamilyRAB, member RAS oncogene GTPases

RAB38 RAB8B RAB8A

2.24e-0465333388
GeneFamilyPhosphodiesterases

PDE1C PDE6A

8.70e-0424332681
GeneFamilyPseudoautosomal region 1|Solute carriers

AKAP17A ASMT

9.44e-0425332715
ToppCellCOVID-19-kidney-Epithelial_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 MDGA2 LRP1B ANO3 RAPGEF4

1.84e-07133435a8abb6b54862123961ae6defbf251ee6e9575258
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE1C STAMBPL1 ARPP21 LRP1B RAPGEF4

9.19e-071844359cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E-|Neuronal / cells hierarchy compared to all cells using T-Statistic

MDGA2 PDE1C LRP1B ANO3 RAPGEF4

1.39e-062004351a3d29a580d1b405a74869a1da3e818c581fc559
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E---L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

MDGA2 PDE1C LRP1B ANO3 RAPGEF4

1.39e-062004356f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E--|Neuronal / cells hierarchy compared to all cells using T-Statistic

MDGA2 PDE1C LRP1B ANO3 RAPGEF4

1.39e-0620043586705dfc05b3e1576543b93883c88fb55b742855
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E|Neuronal / cells hierarchy compared to all cells using T-Statistic

MDGA2 PDE1C LRP1B ANO3 RAPGEF4

1.39e-06200435db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 MDGA2 LRP1B SLC1A6

9.80e-06139434a1945b07f177cde40e7eea03a19236ce76165857
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 MDGA2 LRP1B TMPRSS11A

1.16e-0514543496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MDGA2 SLC8A3 DPY19L2 SLC1A6

2.16e-051704345bb577e2c4bd275fbe4ee23ff8c007b2fcb90e56
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MDGA2 SLC8A3 DPY19L2 SLC1A6

2.37e-0517443466df78280f657978c4a568010ae7d7943869af90
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE1C ARPP21 LRP1B ANO3

2.65e-05179434b35a7f8115c997c390201da01d7cb10b10769aec
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDGA2 PDE1C LRP1B ANO3

2.95e-05184434ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDGA2 PDE1C LRP1B ANO3

2.95e-051844342cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDGA2 PDE1C LRP1B ANO3

2.95e-051844342b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GABRG3 MDGA2 PDE1C ANO3

3.14e-05187434958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GABRG3 MDGA2 PDE1C ANO3

3.14e-0518743448bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANKK1 SLC8A3 DRD2

1.51e-04107433fc07dd90f280191bd643398eac5c8273651d0925
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a|Striatum / BrainAtlas - Mouse McCarroll V32

DRD2 ARPP21 ANO3

1.59e-04109433e8e0f2c5f8c9e45f2b4d173569c94275eedfe432
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX2 LRP1B SMIM26

2.55e-04128433003e133469899a9abe3a7f6d7f580583b281f412
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 MDGA2 LRP1B

2.67e-041304331ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellCOVID-19-kidney-Technical/muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 MDGA2 LRP1B

3.25e-0413943313247bcb21c57c808657e0f543d6f134eeea7cc1
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

MDGA2 SLC8A3 RAPGEF4

3.25e-0413943364c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

GABRG3 MDGA2 SLC1A6

3.76e-04146433c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 MDGA2 LRP1B

3.91e-04148433d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFT140 ASMT MYO5C

3.99e-041494332624ad3926efc9f0f169daae263cef16861f132b
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 MDGA2 LRP1B

4.06e-041504330205318a870e091add66ee4305747dda9f51510d
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFHX2 ARPP21 FCHO1

4.39e-04154433f78b01c19afcbab6319f61e4d6023ecb3d510d24
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAMBPL1 GPR18 FCHO1

4.56e-0415643344ff0acdd5cc3575d6c24a1c2ba11cd9f55359d1
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAMBPL1 GPR18 FCHO1

4.56e-0415643355ba43cec9d79f309e9f633a6469cf03bb621e64
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1C DRD2 DPY19L2

4.64e-04157433c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANKK1 DRD2 HAP1

4.64e-04157433741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

POGLUT3 PRRC1 RAPGEF4

4.64e-041574334183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1C HAP1 NKRF

4.73e-0415843312661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1C HAP1 NKRF

4.73e-041584330792c39e6fc0745095af7812de2d50949540d60f
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1C HAP1 NKRF

4.73e-04158433e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RAB38 SLC8A3 DRD2

4.82e-04159433ecd1daa33549541aee3bf4e139ab6732efc8e74c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1C DPY19L2 LRP1B

4.82e-0415943350d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RAB38 SLC8A3 DRD2

4.82e-041594337b6370c9567da7d40541c6e243efa704ed7e90ae
ToppCellGlobus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MAK ARPP21 ANO3

4.91e-04160433f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCellsevere_influenza-cDC|World / disease group, cell group and cell class (v2)

DPY19L2 LRP1B MYO5C

5.00e-04161433802f8cafb5f499e3b2ec0193d6eb1ac9320b9287
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MAK ARPP21 ANO3

5.00e-04161433ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MDGA2 ANO3 RAPGEF4

5.00e-041614331b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellsevere_influenza-cDC|severe_influenza / disease group, cell group and cell class (v2)

DPY19L2 LRP1B MYO5C

5.00e-041614337716315b8bda904b346cea47edc2c0b507a345c2
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDGA2 STAMBPL1 LRP1B

5.09e-04162433ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MDGA2 LRP1B TMPRSS11A

5.09e-04162433bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAMBPL1 GPR18 LRP1B

5.09e-04162433b46158e260bd2f35702cec73e3b035e8e9ec4469
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAMBPL1 GPR18 FCHO1

5.09e-0416243359f6a9005c4f22f084c25ea36f3cacce5144a9ae
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HAP1 LRP1B MYO5C

5.09e-04162433373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

GABRG3 MDGA2 PDE6A

5.18e-0416343319c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ARPP21 ANO3 MYO5C

5.18e-04163433218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MDGA2 PDE1C ANO3

5.37e-04165433cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MDGA2 PDE1C ANO3

5.37e-041654334f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKK1 GPR18 TTF1

5.46e-04166433ceb0a48c0d853448fd45ac31dde046df9a178571
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AKAP17A ANO3 RAPGEF4

5.46e-04166433a697460dfe72e08fbf7d8e734a16b7dd2c6d86f9
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAMBPL1 FCHO1 RAPGEF4

5.46e-04166433fe006c67a96ffa5a84fba2db96228234668b2a79
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC8A3 STAMBPL1 LRP1B

5.46e-04166433a42268a02a89fc97272e45c4cbe21acf04b7428c
ToppCellControl-Lymphocytic_B|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.56e-04167433956da82394fd6a9f45fc2031796f12cc889542cd
ToppCellControl-Lymphocytic_B-B_cells-B-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.56e-0416743369ed8a4a507190a1a66c4baf1f3e9be21ada39d8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC1A6 ASMT RAPGEF4

5.56e-04167433d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCellControl-Lymphocytic_B-B_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.56e-04167433a15a70d3837b31cc83a2a9e3f1bbfd77a95f2312
ToppCellControl-NK|Control / Disease group and Cell class

RAB38 MAK DPY19L2

5.66e-04168433683d389c8a1e791bfc773e63148115a21a6566db
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B-B_cells-B-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.66e-04168433eeb381b62c7ba263af96de1194ed59e57b6ca3ae
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B-B_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.66e-04168433063d0368d656962b335154c230bdcd9236e7c9ad
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.66e-04168433a7c4251d8a83bc30196a444028a35c17c24dc291
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 VWA8 TMPRSS11A

5.66e-0416843329a6c3ba69e03ccb19efb8ac177b9a162dc1ea43
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 VWA8 TMPRSS11A

5.66e-041684334297be958a4754677df7cf73feba19b0d76f1b4a
ToppCellLPS-IL1RA-Lymphocytic_B|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.85e-0417043356284fbfd1e53f67c8c0b7fba64505a4002adba2
ToppCellLPS-IL1RA-Lymphocytic_B-B_cells-B-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.85e-0417043392e0873f618b2fa60c4d555b10f234d5cbcf3325
ToppCellLPS-IL1RA-Lymphocytic_B-B_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

5.85e-04170433c181991f933b779f99afc3782f292306f209e2ac
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARPP21 GPR18 FCHO1

5.95e-04171433a350a5f840e0fb0ccd29bb29cacc23a89abd8404
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARPP21 GPR18 FCHO1

5.95e-04171433e0a99ca8d4c86b58f54af7755ffd8e0ffbfae5e1
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 SLC8A3 ARPP21

5.95e-04171433b2e753e811a7639956994609f73efcdb62d04f82
ToppCellStriatum|World / BrainAtlas - Mouse McCarroll V32

DRD2 ARPP21 ANO3

6.06e-041724338da598d209b8a6646b9f4de1aed833f6fcbb9909
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 MDGA2 RAB8B

6.16e-041734333c51e7bda1835c25915e50c801b0d643979971a3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 MDGA2 RAB8B

6.16e-04173433a042f78a4c69fcc6b5ca76e9bf01e34cee54c81c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1C DRD2 DPY19L2

6.16e-041734330bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAMBPL1 ARPP21 FCHO1

6.26e-041744334cdf2eedc28d88d18241ee390092426fdf849e79
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 VWA8 TMPRSS11A

6.26e-0417443384f2ffe867f22d2fa79f28737a0aa42bdf2f4804
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARPP21 HAP1 NKRF

6.26e-04174433742c73c9e090848b464323cb17579b86658c6792
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARPP21 HAP1 NKRF

6.26e-041744337fed9722e64c60843092f2ba71256e3043011ef6
ToppCellLPS-antiTNF-Lymphocytic_B-B_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

6.26e-04174433b4c2d1c029fcd0d4926aa79a5b789c713919dcf3
ToppCellLPS-antiTNF-Lymphocytic_B|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

6.26e-04174433cc493654ea3517bc6a145c7f787f304929636f86
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAMBPL1 ARPP21 FCHO1

6.26e-04174433268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellLPS-antiTNF-Lymphocytic_B-B_cells-B-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

6.26e-041744339eb3504f9340517ef5d056503044fbdb9ffeb714
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1C ANO3 RAPGEF4

6.37e-0417543365571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE1C ARPP21 ANO3

6.37e-0417543306af6629766e2054e6995e8cdb3907658fec49d3
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 ARPP21 MYO5C

6.47e-04176433d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1C DRD2 DPY19L2

6.47e-04176433c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellLPS_only-Lymphocytic_B|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

6.58e-041774335ed65e08d773d157840317c72e0d43c261d438d4
ToppCellLPS_only-Lymphocytic_B-B_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

6.58e-04177433c82332c5f656aa26513e4f7525d5d4d733019725
ToppCellLPS_only-Lymphocytic_B-B_cells-B-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARPP21 GPR18 FCHO1

6.58e-041774338a955a7ab84c434f9ad4b467246b8be3cb479406
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1C DRD2 DPY19L2

6.58e-041774338e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

PDE1C LRP1B ANO3

6.69e-04178433ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARPP21 GPR18 FCHO1

6.69e-041784338545c0238d8d833a6a179872d44bfb739310ea17
ToppCellLV|World / Chamber and Cluster_Paper

PDE1C DPY19L2 VWA8

6.91e-041804335ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

IFT140 PDE1C LRP1B

6.91e-04180433b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 LRP1B MYO5C

6.91e-0418043372310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARPP21 GPR18 FCHO1

7.02e-0418143351e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STAMBPL1 HAP1 LRP1B

7.02e-0418143322363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG3 ARPP21 ANO3

7.13e-04182433d41ff834b8fc1d0e23cac7ae261de5f72874e462
DiseaseAcquired Language Disorders

ANKK1 DRD2

1.79e-062402C0454560
DiseaseLanguage Disorders

ANKK1 DRD2

1.07e-054402C0023015
DiseaseDyggve-Melchior-Clausen disease (implicated_via_orthology)

RAB8B RAB8A

1.07e-054402DOID:0111167 (implicated_via_orthology)
DiseaseSmith-McCort dysplasia (implicated_via_orthology)

RAB8B RAB8A

1.79e-055402DOID:0060247 (implicated_via_orthology)
Diseaseneurotic disorder

MDGA2 DRD2 ARPP21

3.51e-04101403EFO_0004257
DiseaseInfiltrating duct carcinoma of female breast

ANKK1 MAK

3.70e-0421402C3165106
DiseaseRetinitis Pigmentosa

IFT140 MAK PDE6A

3.82e-04104403C0035334
DiseaseDrug Use Disorders

PDE1C DRD2 MYO5C

5.13e-04115403C0013222
DiseaseDrug Dependence

PDE1C DRD2 MYO5C

5.13e-04115403C1510472
DiseaseDrug habituation

PDE1C DRD2 MYO5C

5.13e-04115403C0013170
DiseaseSubstance Dependence

PDE1C DRD2 MYO5C

5.13e-04115403C0038580
DiseaseSubstance Use Disorders

PDE1C DRD2 MYO5C

5.13e-04115403C0038586
DiseaseSubstance-Related Disorders

PDE1C DRD2 MYO5C

5.13e-04115403C0236969
DiseaseDrug abuse

PDE1C DRD2 MYO5C

5.13e-04115403C0013146
DiseaseOrganic Mental Disorders, Substance-Induced

PDE1C DRD2 MYO5C

5.13e-04115403C0029231
DiseasePrescription Drug Abuse

PDE1C DRD2 MYO5C

5.13e-04115403C4316881
DiseaseSubstance abuse problem

PDE1C DRD2 MYO5C

5.26e-04116403C0740858
Diseasealcohol use disorder measurement, longitudinal alcohol consumption measurement

DRD2 ANO3

1.16e-0337402EFO_0007645, EFO_0009458
Diseaseschizophrenia, intelligence, self reported educational attainment

PDE1C DRD2 LRP1B RAPGEF4

1.22e-03346404EFO_0004337, EFO_0004784, MONDO_0005090
Diseaseend stage renal disease (is_implicated_in)

MYH9 DRD2

1.42e-0341402DOID:783 (is_implicated_in)
Diseasetrauma exposure measurement

MDGA2 LRP1B RAPGEF4

1.64e-03172403EFO_0010703
Diseasecigarettes per day measurement

MDGA2 PDE1C DRD2 SFPQ

2.87e-03438404EFO_0006525
Diseasediffuse plaque measurement

PDE1C DRD2 VWA8 LRP1B ANO3

3.45e-03758405EFO_0010699
Diseaseaggressive behaviour measurement, ADHD symptom measurement

MDGA2 DRD2

3.86e-0368402EFO_0007826, EFO_0007860

Protein segments in the cluster

PeptideGeneStartEntry
TKRMTNGRRIYYGMN

TTF1

746

Q15361
MQYIERSALRGMLSY

ANKK1

176

Q8NFD2
RVISVMLYRNYLRSM

GPR18

296

Q14330
SQCSMLKYMGRTSYR

ASMT

101

P46597
MSSYQRMLVHRVAAY

ARPP21

191

Q9UBL0
YTDGRSKSMGRMQTY

ANO3

236

Q9BYT9
RFGNMTRVYYREAMG

RAB38

71

P57729
RTITTAYYRGAMGIM

RAB8A

71

P61006
RTITTAYYRGAMGIM

RAB8B

71

Q92930
YRMSLVKRRFATGMY

FCHO1

871

O14526
SRITGMDVYYQRDMI

LRP1B

3921

Q9NZR2
MMFYRLLSIVGRQRA

PDPR

1

Q8NCN5
AGIFVERMYRRTSNM

PDE1C

136

Q14123
ERMYRRTSNMVGLSY

PDE1C

141

Q14123
ADRMSLFMYRTRNGI

PDE6A

91

P16499
YAITDTAYRSMMQDR

MYH9

151

P35579
EREMTFRTEMGLYYS

DPY19L2

141

Q6NUT2
SREMSGMYRCQTSQY

MDGA2

506

Q7Z553
VVMTIYFELSRRMGY

GABRG3

241

Q99928
RRMISDPVYFMERNY

HAP1

496

P54257
RMGMRAAVYYMVTTI

SLC1A6

126

P48664
MNRYTTMRQLGDGTY

MAK

1

P20794
DRYTAVAMPMLYNTR

DRD2

131

P14416
EMRRRLPLANMSYYV

IFT140

1401

Q96RY7
YRDMRTTTNLYLGSM

MLNR

66

O43193
SMYSVVRDRVATVMY

OR1L6

301

Q8NGR2
MRMIANTARTVRYYR

RAPGEF4

951

Q8WZA2
FNRMTVEYVYERMTG

NKRF

461

O15226
MYRNEFTAWYRRMSV

SMIM26

1

A0A096LP01
FTGMSRRQMIYSAAR

PRRC1

416

Q96M27
RRQMIYSAARAIAGM

PRRC1

421

Q96M27
YMRNFSDLRNGMDRS

PPM1B

116

O75688
RDTMLAAAAVYREMY

NDUFAF5

276

Q5TEU4
DYYQSGRMLLRMSQA

ABCD3

356

P28288
YREYMGFIQAMSALR

AKAP17A

221

Q02040
RQREESYSRMGYMDP

SFPQ

591

P23246
SYSRMGYMDPRERDM

SFPQ

596

P23246
NDGTFLMRYRMYETV

POGLUT3

96

Q7Z4H8
DGMGQRRYRTQMSSL

ZFHX2

2061

Q9C0A1
YFRSGVEMERMASVY

STAMBPL1

51

Q96FJ0
SRGMYSNRMRSYKQE

VTI1A

66

Q96AJ9
NERSLGVRVAMYSFM

TAAR2

36

Q9P1P5
VSGSMYRFNRMDGRL

VWA8

1721

A3KMH1
MMYRTVGFGTRSRNL

TMPRSS11A

1

Q6ZMR5
RAFYRIQATRMMTGA

SLC8A3

351

P57103
RMATITMQAYSRGFL

MYO5C

831

Q9NQX4