Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentphagophore

ATG2B ATG2A

4.55e-053822GO:0061908
GeneOntologyCellularComponent3M complex

ANKRA2 CUL7

1.51e-045822GO:1990393
MousePhenono spontaneous movement

ERBB3 FOXN4 DTX4 DHCR7 LRP4 MAPK6

2.22e-05123656MP:0001404
DomainATG2

ATG2B ATG2A

1.95e-052832IPR026849
DomainATG2_CAD

ATG2B ATG2A

1.95e-052832PF13329
DomainATG2_CAD_motif

ATG2B ATG2A

1.95e-052832IPR026885
DomainCTNNB1-bd_N

TCF7L2 LEF1

1.16e-044832IPR013558
DomainCTNNB1_binding

TCF7L2 LEF1

1.16e-044832PF08347
DomainTCF/LEF

TCF7L2 LEF1

1.16e-044832IPR024940
DomainATG_C

ATG2B ATG2A

1.93e-045832PF09333
DomainAutophagy-rel_C

ATG2B ATG2A

1.93e-045832IPR015412
DomainVPS13_N

ATG2B ATG2A

5.37e-048832IPR026854
DomainChorein_N

ATG2B ATG2A

5.37e-048832PF12624
Domainp53-like_TF_DNA-bd

NFAT5 MYRF TBX5

1.69e-0353833IPR008967
DomainAAA+_ATPase

MDN1 RNF213 FIGN ABCG5

3.89e-03144834IPR003593
DomainAAA

MDN1 RNF213 FIGN ABCG5

3.89e-03144834SM00382
DomainCatenin_binding_dom

TCF7L2 LEF1

7.33e-0329832IPR027397
Domain-

TCF7L2 LEF1

7.33e-03298324.10.900.10
PathwayREACTOME_RUNX3_REGULATES_WNT_SIGNALING

TCF7L2 LEF1

2.30e-046562MM15542
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY

TCF7L2 LEF1

2.30e-046562M47736
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY

TCF7L2 LEF1

3.21e-047562M47465
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

ARL4C NCOR2 ABCG5

4.19e-0437563M29790
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION

TCF7L2 LEF1

4.27e-048562MM17229
PathwayREACTOME_BINDING_OF_TCF_LEF_CTNNB1_TO_TARGET_GENE_PROMOTERS

TCF7L2 LEF1

4.27e-048562M27359
PathwayKEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY

TCF7L2 LEF1

4.27e-048562M47413
PathwayREACTOME_RUNX3_REGULATES_WNT_SIGNALING

TCF7L2 LEF1

4.27e-048562M27821
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY

TCF7L2 LEF1

6.83e-0410562M47486
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TCF7L2 LEF1

6.83e-0410562MM15156
Pubmed

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

NCOR2 GSE1 LYL1 SPEN

8.67e-073085426593974
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NCOR2 CRTC3 ZNF609 TCF7L2 FAM193A ANKRA2 INPP5D ATG2A SPEN

1.12e-0643085935044719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 FOCAD HSPG2 NCOR2 MDN1 DNAJC14 SNX8 LRP4 TRMT11 ATG2A BCAM SPEN MYRF

2.78e-061105851335748872
Pubmed

Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis.

ATG2B ATG2A

5.90e-06285228800131
Pubmed

Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.

ATG2B ATG2A

5.90e-06285222219374
Pubmed

Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching.

TCF7L2 LEF1

5.90e-06285221599871
Pubmed

Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas.

TCF7L2 LEF1

5.90e-06285223224985
Pubmed

A conserved ATG2-GABARAP family interaction is critical for phagophore formation.

ATG2B ATG2A

1.77e-05385232009292
Pubmed

The combination of single nucleotide polymorphisms rs6720173 (ABCG5), rs3808607 (CYP7A1), and rs760241 (DHCR7) is associated with differing serum cholesterol responses to dairy consumption.

DHCR7 ABCG5

1.77e-05385229920211
Pubmed

Common Variants in Cholesterol Synthesis- and Transport-Related Genes Associate with Circulating Cholesterol Responses to Intakes of Conventional Dairy Products in Healthy Individuals.

DHCR7 ABCG5

1.77e-05385227052530
Pubmed

Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation.

NCOR2 SPEN

1.77e-05385224268649
Pubmed

GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb.

LEF1 MYB

1.77e-05385221795403
Pubmed

Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors.

NCOR2 ATXN1

1.77e-05385215016912
Pubmed

TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state.

TCF7L2 LEF1

1.77e-05385234525377
Pubmed

Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line.

TCF7L2 LEF1

1.77e-05385214661054
Pubmed

Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies.

TCF7L2 LEF1

1.77e-05385232403323
Pubmed

Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4.

TCF7L2 LEF1

1.77e-05385212446687
Pubmed

Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation.

TCF7L2 LEF1

1.77e-05385221282610
Pubmed

DHCR7 promotes lymph node metastasis in cervical cancer through cholesterol reprogramming-mediated activation of the KANK4/PI3K/AKT axis and VEGF-C secretion.

DHCR7 KANK4

1.77e-05385238211648
Pubmed

The transcription factor Maz is essential for normal eye development.

LRP4 LEF1 TBX5

1.82e-052185332571845
Pubmed

Interaction network of human early embryonic transcription factors.

NCOR2 ZNF609 TCF7L2 GSE1 ATXN1 RPN1 SPEN

2.52e-0535185738297188
Pubmed

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.

NCOR2 ZNF609 GSE1

2.75e-052485333722704
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF704 ZNF609 TCF7L2 ATXN1 ZNF76 NFAT5 LEF1 MNT MYB TBX5

2.82e-05808851020412781
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DMXL2 ERBB3 ZNF609 GSE1 TPP1 MTREX GTPBP1 LETM1 GNPAT

3.06e-0565085938777146
Pubmed

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells.

LEF1 MYB

3.53e-05485212244173
Pubmed

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis.

TCF7L2 LEF1

3.53e-05485215684397
Pubmed

A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells.

TCF7L2 LEF1

3.53e-05485233587034
Pubmed

Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.

TCF7L2 LEF1

3.53e-05485212556497
Pubmed

Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.

NCOR2 SPEN

3.53e-05485216129689
Pubmed

TCF transcription factors: molecular switches in carcinogenesis.

TCF7L2 LEF1

3.53e-05485210528152
Pubmed

Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.

NCOR2 ATXN1

3.53e-05485216121196
Pubmed

Agonist-antagonist induced coactivator and corepressor interplay on the human androgen receptor.

NCOR2 SPEN

3.53e-05485215062576
Pubmed

Mapping canonical Wnt signaling in the developing and adult retina.

TCF7L2 LEF1

3.53e-05485217065530
Pubmed

Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.

TCF7L2 LEF1 TBX5

3.95e-052785323824573
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

NCOR2 ZNF609 MTREX

3.95e-052785323395962
Pubmed

Human transcription factor protein interaction networks.

HSPG2 NCOR2 ZNF609 TCF7L2 GSE1 ATXN1 RPN1 CUL7 GTPBP1 FIGN SPEN MNT MYB

4.24e-051429851335140242
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOR2 TCF7L2 GSE1 SPEN

5.27e-058385428794006
Pubmed

Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2.

TCF7L2 LEF1

5.87e-05585221285352
Pubmed

Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia.

TCF7L2 MYB

5.87e-05585220027603
Pubmed

Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans.

ATG2B ATG2A

5.87e-05585222710871
Pubmed

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1.

NCOR2 SPEN

5.87e-05585215778499
Pubmed

Identification of novel ErbB3-interacting factors using the split-ubiquitin membrane yeast two-hybrid system.

ERBB3 RPN1

5.87e-05585212840049
Pubmed

Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.

NCOR2 ATXN1

5.87e-05585221475249
Pubmed

The APC tumor suppressor binds to C-terminal binding protein to divert nuclear beta-catenin from TCF.

TCF7L2 LEF1

5.87e-05585215525529
Pubmed

Regulation of the murine Ddelta2 promoter by upstream stimulatory factor 1, Runx1, and c-Myb.

LEF1 MYB

5.87e-05585215778374
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

ZNF609 MDN1 CUL7 AMOTL2 MTREX SPEN

6.89e-0528285623667531
Pubmed

A census of human transcription factors: function, expression and evolution.

TCF7L2 FOXN4 ZNF76 LYL1 NFAT5 LEF1 MYRF MNT MYB TBX5

7.48e-05908851019274049
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOR2 ZNF609 TCF7L2 GSE1 INPP5D UNG MTREX GTPBP1 SPEN MNT MYB

7.76e-051103851134189442
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FOCAD OR51L1 IGSF10 MDN1 GSE1 RPN1 ZNF618 RNF213 AMOTL2

7.96e-0573685929676528
Pubmed

Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling.

ERBB3 LRP4 LEF1

7.98e-053485323293290
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

NCOR2 CRTC3 ZNF609 GSE1 SLITRK5

8.24e-0518085535198878
Pubmed

NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

TCF7L2 LEF1

8.80e-05685216714285
Pubmed

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.

TCF7L2 LEF1

8.80e-0568529488439
Pubmed

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain.

TCF7L2 LEF1

8.80e-05685223152144
Pubmed

Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein.

LEF1 MYB

8.80e-05685215094381
Pubmed

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

NCOR2 SPEN

8.80e-05685225915022
Pubmed

SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts.

TCF7L2 LEF1

8.80e-05685220128911
Pubmed

ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules.

TCF7L2 LEF1

8.80e-05685212408825
Pubmed

Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP.

TCF7L2 LEF1

8.80e-05685224748645
Pubmed

Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function.

LRP4 LEF1

8.80e-05685237091972
Pubmed

Dazap2 modulates transcription driven by the Wnt effector TCF-4.

TCF7L2 LEF1

8.80e-05685219304756
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CRTC3 FAM193A CUL7 AMOTL2 MTREX LETM1 WDR62

1.14e-0444685724255178
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DTX4 AMOTL2 SPEN MYRF

1.18e-0410285410231032
Pubmed

The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling.

NCOR2 SPEN

1.23e-04785211867749
Pubmed

β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells.

TCF7L2 LEF1

1.23e-04785232820720
Pubmed

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.

TCF7L2 LEF1

1.23e-04785218772112
Pubmed

Gene expression analysis of canonical Wnt pathway transcriptional regulators during early morphogenesis of the facial region in the mouse embryo.

TCF7L2 LEF1

1.23e-04785219303461
Pubmed

TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase-dependent.

TCF7L2 LEF1

1.23e-04785216204248
Pubmed

Wnt signaling mediates regional specification in the vertebrate face.

TCF7L2 LEF1

1.64e-04885217699607
Pubmed

Shh signaling is essential for rugae morphogenesis in mice.

LRP4 LEF1

1.64e-04885222038040
Pubmed

ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation.

ANKRA2 ZNF76

1.64e-04885215280358
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

NCOR2 ZNF609 TCF7L2 GSE1 RPN1 DHCR7 BCAM MNT LETM1 RNF111 GNPAT

1.66e-041203851129180619
Pubmed

Transcriptome profile of subsynaptic myonuclei at the neuromuscular junction in embryogenesis.

TCF7L2 AMOTL2

2.10e-04985237994470
Pubmed

Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis.

TCF7L2 LEF1

2.10e-04985217335794
Pubmed

Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data.

BCAM ABCG5

2.10e-04985220370913
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PHKB NCOR2 ZNF609 GSE1 DUSP4 RNF213 UNG MARVELD2 CUL7 LETM1

2.41e-041049851027880917
Pubmed

Regulation of GATA-3 expression during CD4 lineage differentiation.

NFAT5 MYB

2.62e-041085221357543
Pubmed

Dual-specificity phosphatase 18 modulates the SUMOylation and aggregation of Ataxin-1.

ATXN1 DUSP4

2.62e-041085229852174
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FOCAD PLEKHH1 DMXL2 ERBB3 DNAJC14 TPP1 LRP4 ZNF76 HUNK AMOTL2 RNF111

2.93e-041285851135914814
Pubmed

Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis.

DHCR7 GNPAT

3.20e-041185211792727
Pubmed

Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects.

TCF7L2 LEF1

3.20e-041185221452227
Pubmed

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung.

TCF7L2 LEF1

3.20e-041185211731265
Pubmed

Tcf7L2 is essential for neurogenesis in the developing mouse neocortex.

TCF7L2 LEF1

3.20e-041185229751817
Pubmed

Sharp, an inducible cofactor that integrates nuclear receptor repression and activation.

NCOR2 SPEN

3.20e-041185211331609
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

ZNF609 DNAJC14 SNX8 LRP4 MARVELD2 BCAM MYRF GNPAT

3.81e-0471985835337019
Pubmed

Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.

TCF7L2 LEF1

3.83e-041285232414917
Pubmed

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1.

TCF7L2 LEF1

3.83e-041285210631168
Pubmed

Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo.

LEF1 TBX5

3.83e-041285212490567
Pubmed

Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion.

TCF7L2 LEF1

3.83e-041285219700620
Pubmed

All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

TCF7L2 LEF1

3.83e-041285211266540
Pubmed

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.

FRMD4A NCOR2 NFAT5

4.36e-046085319075228
Pubmed

Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome.

LEF1 TBX5

4.52e-041385212668638
Pubmed

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.

TCF7L2 LEF1

5.27e-041485215226261
Pubmed

Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye.

LEF1 TBX5

5.27e-041485233075808
Pubmed

Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling.

TCF7L2 LEF1

5.27e-041485233195246
Pubmed

Individual Limb Muscle Bundles Are Formed through Progressive Steps Orchestrated by Adjacent Connective Tissue Cells during Primary Myogenesis.

TCF7L2 TBX5

5.27e-041485232160556
Pubmed

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice.

TCF7L2 LEF1

5.27e-041485210090727
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOR2 ZNF609 GSE1 UNG

5.39e-0415285438360978
Pubmed

Defining the membrane proteome of NK cells.

NCOR2 ABHD15 MDN1 DNAJC14 RPN1 DHCR7 RNF213 ERMP1 GTPBP1 GNPAT

5.61e-041168851019946888
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOR2 ZNF609 FAM193A GSE1 ATG2B WDR62

5.72e-0441885634709266
InteractionTBXT interactions

NCOR2 ZNF609 TCF7L2 GSE1 ATXN1 SPEN

8.40e-06116836int:TBXT
InteractionTLE3 interactions

NCOR2 CRTC3 ZNF609 TCF7L2 FAM193A GSE1 ATXN1 FIGN SPEN

2.42e-05376839int:TLE3
InteractionPRDM1 interactions

NCOR2 ZNF609 TCF7L2 GSE1 ATXN1

2.51e-0584835int:PRDM1
InteractionPAX2 interactions

NCOR2 ZNF609 GSE1 ATXN1 PRDM14

2.66e-0585835int:PAX2
InteractionFHL2 interactions

NCOR2 ATXN1 ZNF76 SAXO1 MAP10 SPEN NFAT5 WDR62 RNF111

3.63e-05396839int:FHL2
InteractionFNDC8 interactions

ZNF609 LRP4 ZNF76

5.26e-0518833int:FNDC8
Cytoband15q21

MAPK6 RNF111

1.84e-041185215q21
CoexpressionRODRIGUES_NTN1_TARGETS_DN

HSPG2 ARL4C GSE1 RNF213 BCAM SPEN NFAT5

7.48e-07161827M11857
CoexpressionGSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_DN

FRMD4A NCOR2 TCF7L2 ATXN1 INPP5D DHCR7 WDR62

1.47e-06178827M6728
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOR2 DMXL2 TCF7L2 FAM193A MDN1 GSE1 ATXN1 DUSP4 MAPK6 MTREX SPEN MNT

1.38e-058568212M4500
CoexpressionHEVNER_CORTEX_CAUDAL_VENTRICULAR_ZONE

ZNF704 NCOR2 LEF1 MYB

2.15e-0552824MM442
CoexpressionGSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN

ANKRA2 GID4 ATG2B BRI3 CAB39L SPEN

3.74e-05198826M6128
CoexpressionGSE17580_TREG_VS_TEFF_DN

ARL4C ABHD15 GID4 ATG2B LEF1 RNF111

3.96e-05200826M3671
CoexpressionAtlasalpha beta T cells, preT.DN3A.Th, Lin-/lo CD25hi CD44- CD28-, Thymus, avg-3

FOCAD ZNF704 FRMD4A GSE1 GID4 DHCR7 CUL7 LEF1 MYB

2.39e-05416799GSM791146_500
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRUNE1 ARL4C ATXN1 CFAP61 ATG2A DTHD1

7.65e-07167846abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ERBB3 GSE1 ATXN1 KANK4 NFAT5 ABCG5

1.39e-061858461d874608aa2062024323512f68889219471b2f00
ToppCellCOVID-19_Severe-HSPC|World / disease group, cell group and cell class

IGSF10 ZNF704 HSPG2 BCAM FIGN MYB

1.57e-06189846555c0b13f1508b9e3712b36d77144e73e828bc76
ToppCellCOVID-19-COVID-19_Severe-Others-HSPC|COVID-19_Severe / Disease, condition lineage and cell class

IGSF10 ZNF704 HSPG2 ZNF618 FIGN MYB

2.12e-0619984625de67b6c9c8d6bb9a538e071a40ef865906c95d
ToppCellControl-Control-Lymphocyte-T/NK-dn_T|Control / Disease, condition lineage and cell class

ZNF704 FRMD4A ARL4C DTHD1 LEF1 MYB

2.18e-0620084610882c59b7aaf8bd4b5c00aa4ddbb9f7ac5b2cf5
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-dn_T|Int-URO / Disease, condition lineage and cell class

TAS2R4 TRMT11 IRGQ MAPK6 DTHD1 MYB

2.18e-06200846020439d9e70fff7246650ab0e9105236688c3ec3
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

PLEKHH1 ERBB3 MYRF PIGZ PADI3

2.63e-0611584515b2c11225802cc15c01165d84a755432f02d82f
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF704 ARL4C DTHD1 LEF1 MYB

1.03e-05152845405d19b290232bb3e564d61c0cff0cfdd247bdff
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF704 ARL4C DTHD1 LEF1 MYB

1.03e-0515284506fa7d8acc8f56de00af9bee17884595b300410e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ZNF704 ARL4C DTHD1 LEF1 MYB

1.06e-05153845b101cb1bce5db785dab46b6c4f7be9c3efe48b0e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZNF704 ARL4C DTHD1 LEF1 MYB

1.06e-05153845487388082bb596809ba1caf9197626b6814792ab
ToppCellURO-Lymphocyte-T_NK-CD4_TEM|URO / Disease, Lineage and Cell Type

ZNF704 FRMD4A KANK4 UNG LEF1

1.31e-05160845e406f77b1c1a01d74f39ba65f99d5f8c7d75faf1
ToppCellInt-URO-Lymphocyte-T_NK-dnT|Int-URO / Disease, Lineage and Cell Type

TAS2R4 TRMT11 MAPK6 DTHD1 MYB

1.86e-05172845e70299573da1679d6d286c3a43699cbff76e207d
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HSPG2 DUSP4 ZNF76 IRGQ WDR62

1.86e-051728453b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

FRMD4A ERBB3 SLITRK5 CAB39L FIGN

1.92e-051738456fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4A ABHD15 DTX4 HUNK MYB

1.97e-05174845a9f34d1237f335d27c5560ff514368f4709f9144
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4A TCF7L2 UNG ERMP1 MARVELD2

2.20e-05178845de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF704 DUSP4 HUNK LEF1 TBX5

2.20e-051788458bae5db100f4563aa1fc7f881e7f8c59d669e37a
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF704 DUSP4 HUNK LEF1 TBX5

2.20e-05178845bc0336692b84bd0fa49747ed5a031b8ed8afa0fd
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF704 DUSP4 HUNK LEF1 TBX5

2.38e-05181845dff264815a3569f5666d0bbc3867c0496cd78774
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHH1 ERMP1 CFAP61 HUNK NFAT5

2.38e-051818456a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF704 ARL4C DTHD1 LEF1 MYB

2.44e-051828456c9a48037fa002bc528875538bdaaf15696d68b6
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DMXL2 RNF213 ERMP1 SPEN NFAT5

2.64e-05185845a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DMXL2 RNF213 ERMP1 SPEN NFAT5

2.71e-051868458571956890fc9894d766ba294a28e376b4aba428
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPN1 TPP1 INPP5D DTX4 MTREX

2.93e-051898456dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 TCF7L2 ATXN1 MARVELD2 MAPK6

2.93e-051898456d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCellCOVID-19_Severe-HSPC|COVID-19_Severe / disease group, cell group and cell class

IGSF10 ZNF704 HSPG2 FIGN MYB

2.93e-0518984596015439971e2e5b8d6294ca5a6b873c7774e925
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPN1 TPP1 INPP5D DTX4 MTREX

2.93e-051898453ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPN1 TPP1 INPP5D DTX4 MTREX

2.93e-05189845875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPN1 TPP1 INPP5D DTX4 MTREX

2.93e-0518984597ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF704 ERBB3 ANKRA2 MTREX NFAT5

3.16e-05192845916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellT/NK_cells-CD8+_Effector_T_cell|World / Lineage and Cell class

ARL4C ATXN1 DUSP4 ATG2A DTHD1

3.23e-0519384579fa0f482cd98642b1d38835cda98622f21e5bd0
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-CD8_Tmem|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARL4C ATXN1 DUSP4 RNF213 DTHD1

3.23e-0519384553b3f9a8967541ca817a250439a7928d36b45386
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLEKHH1 ERBB3 ERMP1 AMOTL2 MYRF

3.32e-05194845cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

ZNF704 FRMD4A ARL4C GSE1 HUNK

3.48e-0519684538da0751941adca650fe9b383d9f343153978eb5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

ZNF704 FRMD4A ARL4C GSE1 HUNK

3.48e-05196845721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FRMD4A TCF7L2 TPP1 SIGLEC11 BCAM

3.65e-051988459aaff68107ae4542f904b142d23669f2fcd557ac
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FRMD4A TCF7L2 TPP1 SIGLEC11 BCAM

3.65e-051988455aaf3861c53763cf09bb628c9d2eabb6a7277021
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLEKHH1 ZNF704 ERBB3 AMOTL2 MYRF

3.74e-051998455d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLEKHH1 ZNF704 ERBB3 AMOTL2 MYRF

3.74e-051998459dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLEKHH1 ZNF704 ERBB3 AMOTL2 MYRF

3.74e-051998456fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLEKHH1 ZNF704 ERBB3 AMOTL2 MYRF

3.74e-051998451bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FRMD4A SNX8 GTPBP1 MAP10 LETM1

3.83e-0520084588d713dfc792e7609bf7ecfb28f87cb748088570
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-dn_T|COVID-19_Severe / Disease, condition lineage and cell class

ZNF704 ARL4C DTHD1 LEF1 MYB

3.83e-05200845d01aa5fccada22f97d8350ad5888df2aadb5bb1c
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_T_naive|Influenza_Severe / Disease, condition lineage and cell class

HSPG2 ARL4C UNG LEF1 MYB

3.83e-052008450382f8fc27d18003761725e714beb6b3f3150057
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PLEKHH1 ERBB3 MYRF PIGZ

8.40e-051228442880f25d10a7765e55a2aa20c7a6ef74cea19c4d
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PLEKHH1 ERBB3 MYRF PIGZ

8.40e-05122844ecd0e54dd829201290212ea2ff7c8e7eec19c0e9
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PLEKHH1 ERBB3 MYRF PIGZ

8.40e-05122844cffd7730bda90828efc0def452cabb44cf93ab48
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Synpr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLEKHH1 ERBB3 FIGN MYRF

1.21e-041348443dd4b5eddc94c1d49ab23b287ee234db3a55331b
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGSF10 HSPG2 OR52N5 MYB

1.31e-041378446d90da42dcc06aa895f920218055068f3c76d57d
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ERBB3 TCF7L2 LRP4 FIGN

1.39e-04139844a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ERMP1 BCAM HUNK

1.63e-041458448da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLEKHH1 ERBB3 FIGN MYRF

1.77e-0414884444128692824ca419fface0af41099c17135933ce
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLEKHH1 ERBB3 FIGN MYRF

1.77e-04148844d60f93311cfa718d026a0dbf61771bbbcbb79146
ToppCellCOVID-19_Severe-Lymphoid_T/NK-dn_T|COVID-19_Severe / Disease group, lineage and cell class

ARL4C DTHD1 LEF1 MYB

2.16e-0415684483f25683e0f55472b56f915ee176fc05efc33a31
ToppCellsevere_influenza-CD4+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

HSPG2 ARL4C LEF1 MYB

2.27e-04158844ff3fa4bd06e01363429aec4bb587b95819bf0fc9
ToppCellcellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARL4C LEF1 WDR62 MYB

2.33e-04159844048b6a97568242c8846034277680632e5de75840
ToppCell10x5'v1-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MARVELD2 IRGQ LEF1 MYB

2.38e-0416084430b7f24e0c3ecfa618b4e31678e18c8a4405a8d7
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERBB3 FOXN4 HUNK PADI3

2.44e-041618442d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 PLEKHH1 SAXO1 PRDM14

2.50e-041628449f568836199a05f696294caac1ea3fa413984423
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-CLP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

INPP5D LYL1 LEF1 MYB

2.62e-04164844f5cacd7b2329cb0c7c1696eb4d8f89a4bbd9dda1
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARL4C DMXL2 LEF1 ATP2B3

2.68e-04165844651d40eadb1b34de618af94c167f43635729d43f
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

FRMD4A ERBB3 SLITRK5 FIGN

2.68e-041658446ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellremission-HSPC|World / disease stage, cell group and cell class

IGSF10 HSPG2 PIGZ MYB

2.74e-04166844d269ee6f7adb55b05dcb5eaea96629ccb0b2d6e3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRTC3 ZNF609 MAPK6 LEF1

2.80e-04167844ced6ed9b412739c6ced622523347c10295edbf53
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRMD4A SLITRK5 CAB39L FIGN

2.87e-0416884488c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

HSPG2 ABHD15 SLITRK5 MYB

2.87e-04168844dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellmild_COVID-19-HSPC|mild_COVID-19 / disease group, cell group and cell class (v2)

ZNF704 HSPG2 FIGN MYB

2.87e-0416884490b33962adb77d8326dee403712118398b4d1315
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ERBB3 FOXN4 KANK4

2.93e-04169844d18b823836ca6fba79a2d2f10cb9966fa2623af2
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ERBB3 FOXN4 KANK4

2.93e-04169844befb9b1618ea30fbf8983bcc493853da53b809c3
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

FRMD4A ERBB3 SLITRK5 FIGN

2.93e-04169844a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellmild_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

ZNF704 HSPG2 FIGN MYB

3.00e-0417084485c476e0bc496445e868a88849960598d97bdea2
ToppCellCOVID-19_Convalescent-Hematopoietic_SC|COVID-19_Convalescent / Disease group, lineage and cell class

IGSF10 HSPG2 PIGZ MYB

3.00e-041708448a73d5334eed1cd9fdcc3ebeae0bdf9f945c228a
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGSF10 HSPG2 PIGZ MYB

3.07e-041718442031797d579ce373921affad70da6e50eec13664
ToppCellremission-HSPC|remission / disease stage, cell group and cell class

IGSF10 HSPG2 PIGZ MYB

3.07e-0417184441b424e58470a2fc25632aea50a37c7c5ea17645
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGSF10 HSPG2 PIGZ MYB

3.07e-04171844a4e13b304ef414722ffdc06560deeab41785e956
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ARL4C ATXN1 RNF213 DTHD1

3.07e-041718442e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellPBMC-Convalescent-Hematopoietic-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGSF10 HSPG2 PIGZ MYB

3.07e-04171844172db31a37b72fb87fe5f0f79da51866b90dd1ad
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGSF10 HSPG2 PIGZ MYB

3.14e-041728448fd3db757d54949bd583d5f0eadf63a32342cb9d
ToppCellPBMC-Convalescent-Hematopoietic-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGSF10 HSPG2 PIGZ MYB

3.14e-04172844da78f7a71b7f05c5c484c9ed19ba37c55d35e870
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDN1 DUSP4 LEF1 PADI3

3.14e-04172844226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGSF10 HSPG2 PIGZ MYB

3.14e-04172844382cb5fea099110eb026a8bba6cf4c28763ea52f
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF704 DUSP4 LEF1 TBX5

3.21e-041738443059325901b1e5e12a1a91183f14267288b2f600
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF704 DUSP4 LEF1 TBX5

3.21e-0417384436c8338463ee4cc432f568728d55989360f9a68d
ToppCell5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 SLITRK5 CAB39L FIGN

3.28e-04174844c9d4e375dedd2b099a9ed70ec38ff35bbb0ce48a
ToppCell5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 SLITRK5 CAB39L FIGN

3.28e-041748441463c98f8f519dd030587abbdbeb1b4e1bca5dd1
ToppCell5'-GW_trimst-2-LymphNode-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 SLITRK5 CAB39L FIGN

3.28e-04174844d421c0069d24cb560a3a429929e3cd1eceaeabcf
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXN4 ATP2B3 WDR62 MYB

3.28e-041748440227fea1678baa9168bd47c3b4aacb2592bb5867
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXN4 ATP2B3 WDR62 MYB

3.28e-04174844c2f8c59fca5f1ff6ffa6dc8cfce62da4b19fe9b3
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXN4 ATP2B3 WDR62 MYB

3.28e-0417484484024c04b0ce9f7068677d2d99ede56882b7dbd2
ToppCellsevere_COVID-19-HSPC|severe_COVID-19 / disease group, cell group and cell class (v2)

ZNF704 HSPG2 FIGN MYB

3.28e-041748446d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP4 HUNK LEF1 TBX5

3.35e-04175844d2ff8fedca9039cbd45cfd9dec88f4edbe7fe4fc
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF704 DUSP4 HUNK TBX5

3.35e-041758442a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ERBB3 KANK4 AMOTL2 FIGN

3.35e-04175844bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP4 HUNK LEF1 TBX5

3.35e-04175844a7310950e8d51b3004ea3aee8ce9948fe8655112
ToppCellPosterior_cortex-Macroglia|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ERBB3 TCF7L2 LRP4 MYRF

3.35e-041758448bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF704 DUSP4 HUNK TBX5

3.35e-04175844fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ERBB3 KANK4 AMOTL2 FIGN

3.35e-041758448b010220cdfb680ec839572f4933adfb85045ea6
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ERBB3 KANK4 AMOTL2 FIGN

3.35e-041758440b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ERBB3 ATXN1 KANK4 GNPAT

3.42e-041768441e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

ATXN1 RNF213 SPEN NFAT5

7.52e-0550494GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
DrugNiclosamide [50-65-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

NCOR2 ZNF609 ATXN1 DUSP4 CUL7 AMOTL2 MNT

1.96e-061588474136_UP
DrugThiostrepton [1393-48-2]; Down 200; 2.4uM; MCF7; HT_HG-U133A

FRMD4A HSPG2 ARL4C TCF7L2 DUSP4 WDR62 MYB

6.64e-061908474385_DN
DrugTorsemide [56211-40-6]; Down 200; 11.4uM; HL60; HT_HG-U133A

ARL4C DMXL2 TCF7L2 GID4 INPP5D DTX4 SLITRK5

7.88e-061958472956_DN
DrugPiromidic acid [19562-30-2]; Down 200; 13.8uM; MCF7; HT_HG-U133A

HSPG2 ARL4C TCF7L2 DUSP4 CUL7 SPEN NFAT5

7.88e-061958474398_DN
DrugNiclosamide [50-65-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

ANKRA2 ATXN1 DUSP4 AMOTL2 NFAT5 MNT

3.15e-051638461498_UP
DrugDigoxin [20830-75-5]; Up 200; 5.2uM; MCF7; HT_HG-U133A

TCF7L2 FAM193A TPP1 DUSP4 AMOTL2 NFAT5

3.49e-051668465324_UP
Drugwortmannin; Up 200; 1uM; MCF7; HT_HG-U133A_EA

ANKRA2 GID4 DUSP4 ATG2B CUL7 MNT

4.68e-05175846869_UP
DrugDigoxigenin [1672-46-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A

FRMD4A TPP1 DUSP4 AMOTL2 NFAT5 PADI3

5.48e-051808463397_UP
DrugCapecitabine

ERBB3 TCF7L2 MYRF MYB

5.87e-0557844ctd:D000069287
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

PHKB ANKRA2 ATXN1 ATG2B CUL7 MNT

6.01e-051838461074_UP
Drug15d-PGJ2; Down 200; 10uM; HL60; HT_HG-U133A

ARL4C GSE1 INPP5D UNG MNT MYB

6.19e-051848462691_DN
Drugfluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

PHKB ARL4C ZNF609 ANKRA2 ATXN1 DUSP4

6.57e-051868466996_UP
DrugICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A_EA

PHKB ARL4C ZNF609 TCF7L2 ANKRA2 TPP1

6.77e-051878461043_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

GSE1 UNG IRGQ LYL1 LETM1 MYB

7.39e-051908461612_DN
DrugNadolol [42200-33-9]; Up 200; 13uM; MCF7; HT_HG-U133A

PRUNE1 HSPG2 NCOR2 ZNF609 ATXN1 TRMT11

8.29e-051948464139_UP
DrugPF-00875133-00 [351322-64-0]; Up 200; 10uM; MCF7; HT_HG-U133A

GID4 TPP1 DUSP4 LRP4 WDR62 TBX5

8.29e-051948465923_UP
DrugClozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A

HSPG2 NCOR2 DMXL2 DUSP4 ZNF76 TBX5

8.53e-051958465265_UP
Drugalpha-estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A

FRMD4A NCOR2 TPP1 LRP4 PRDM14 ATP2B3

8.53e-051958464434_UP
DrugDelcorine; Down 200; 8.4uM; PC3; HT_HG-U133A

FRMD4A NCOR2 ZNF609 BCAM CUL7 LEF1

8.53e-051958463715_DN
DrugPregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A

PHKB FRMD4A ARL4C TCF7L2 BCAM NFAT5

8.77e-051968462856_DN
DrugEthambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A

FRMD4A HSPG2 NCOR2 ZNF609 WDR62 MYB

9.02e-051978464120_UP
DrugIsometheptene mucate; Down 200; 8.2uM; HL60; HT_HG-U133A

TAS2R4 ZNF609 TCF7L2 DUSP4 MYB TBX5

9.02e-051978463145_DN
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

FRMD4A NCOR2 ZNF609 TCF7L2 SPEN PADI3

9.02e-051978465276_UP
DrugBrompheniramine maleate [980-71-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A

HSPG2 ARL4C DMXL2 ZNF609 CUL7 TBX5

9.02e-051978464131_UP
DrugIodixanol [92339-11-2]; Down 200; 2.6uM; HL60; HT_HG-U133A

ERBB3 TCF7L2 GID4 TPP1 DUSP4 ZNF76

9.28e-051988463023_DN
DrugFuraltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A

FRMD4A ZNF609 SLITRK5 LRP4 ERMP1 CUL7

9.28e-051988463756_DN
DrugGriseofulvin [126-07-8]; Down 200; 11.2uM; PC3; HT_HG-U133A

PHKB HSPG2 ATXN1 TPP1 SLITRK5 IRGQ

9.28e-051988467363_DN
DrugLY294002; Up 200; 10uM; PC3; HG-U133A

TAS2R4 DMXL2 TCF7L2 ATXN1 INPP5D NFAT5

9.28e-05198846461_UP
Drugalpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A

HSPG2 NCOR2 TCF7L2 TPP1 ZNF76 NFAT5

9.81e-052008462670_DN
DiseaseAntihypertensive use measurement

HSPG2 TCF7L2 SRBD1 FIGN NFAT5 LEF1

9.16e-05265816EFO_0009927
Diseasemyelofibrosis (implicated_via_orthology)

NCOR2 MYB

1.11e-046812DOID:4971 (implicated_via_orthology)
DiseaseFuchs endothelial corneal dystrophy

TCF7L2 KANK4

3.30e-0410812Orphanet_98974
Diseaseapolipoprotein B measurement

ABHD15 CRTC3 DUSP4 SNX8 KANK4 BCAM MYRF ABCG5

4.74e-04663818EFO_0004615
Diseasetriglycerides to total lipids in medium VLDL percentage

BCAM MYRF ABCG5

7.03e-0463813EFO_0022335
Diseaseeosinophil count

NCOR2 CRTC3 ERBB3 FAM193A MDN1 GSE1 ATXN1 RPN1 INPP5D ERMP1 MYRF MYB

7.26e-0414888112EFO_0004842
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

LRP4 BCAM NFAT5 MYRF ABCG5

8.13e-04264815EFO_0008317, EFO_0020944
Diseasefilaggrin gene expression measurement

FRMD4A ZNF618

8.71e-0416812EFO_0020899
Diseaselevel of Phosphatidylethanolamine (18:0_20:4) in blood serum

MYRF RNF111

1.23e-0319812OBA_2045140
Diseaseneutrophil percentage of leukocytes

CRTC3 ATXN1 RPN1 BRI3 CFAP61 DTHD1 MYB

1.45e-03610817EFO_0007990
Diseasetotal blood protein measurement

NCOR2 ZNF609 TCF7L2 ATXN1 ZNF618 SNX8

1.49e-03449816EFO_0004536
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

NCOR2 KANK4 BCAM MYRF ABCG5

1.77e-03315815EFO_0004612, EFO_0008591
Diseaselevel of Phosphatidylinositol (18:0_20:4) in blood serum

KANK4 MYRF

1.81e-0323812OBA_2045158
Diseaseclinical and behavioural ideal cardiovascular health

TCF7L2 NFAT5

1.81e-0323812EFO_0007654
DiseaseCoronary heart disease

TCF7L2 ABCG5

1.98e-0324812C0010068
DiseaseVaricose veins

FAM193A RPN1 SLITRK5 CAB39L

1.99e-03193814HP_0002619
Diseasemyeloproliferative disorder

RPN1 MYB

2.14e-0325812EFO_0004251
Diseasefasting blood glucose measurement, HOMA-B, fasting blood insulin measurement

TCF7L2 MYRF

2.14e-0325812EFO_0004465, EFO_0004466, EFO_0004469
DiseaseHyperplasia

TCF7L2 MAPK6

2.69e-0328812C0020507

Protein segments in the cluster

PeptideGeneStartEntry
HVLQTAHPSPLSVYR

UNG

271

P13051
TRSPTVEYISAHPHI

CAB39L

111

Q9H9S4
PQYPHVVLAHETTTA

AMOTL2

211

Q9Y2J4
AYHSQRHSLLTPVTP

ERBB3

1131

P21860
HSLTSALHYLVPVRP

CFAP61

606

Q8NHU2
LHELIPATTYHVQPA

ARL4C

146

P56559
VTGIPTHHPRVYNIH

BRI3

46

O95415
ILVLHHPTTISPRYQ

GTPBP1

496

O00178
HHVVPPSTVTEDYLR

GSE1

206

Q14687
IHTSPSPGIQVRHVY

ANKRA2

101

Q9H9E1
AAHVLSPTLPQYHPT

DMXL2

1336

Q8TDJ6
PGHRSYALSPHTVIQ

ATXN1

421

P54253
VYHPVQLSTPHAVGV

DHCR7

326

Q9UBM7
PYSPAVSHHIEAVVR

DTX4

21

Q9Y2E6
LIHPTLYATPPFTHS

FAM193A

471

P78312
YTGISHITPHIPEIN

ERMP1

716

Q7Z2K6
LHSPPSEHYTIIFNT

ATP2B3

961

Q16720
LGYLPPTVITILHTH

ATG2A

1101

Q2TAZ0
TDFHSVPPHYTELLT

ATG2B

616

Q96BY7
PDHTLTTELFHSNPY

ABHD15

366

Q6UXT9
HAEATIILHVESPPY

HSPG2

3286

P98160
QPSHAVHPLTPLITY

LEF1

146

Q9UJU2
VHPLTPLITYSDEHF

LEF1

151

Q9UJU2
LTPASSTHPNLHAYL

PRUNE1

326

Q86TP1
PHSLSYPVQIARTHT

NCOR2

21

Q9Y618
LTLDTLTHPGYPHSS

PLAC4

86

Q8WY50
HTVPSLHAGLPSQEY

FIGN

171

Q5HY92
VGISPDTHRVPYHIS

DNAJC14

606

Q6Y2X3
QDPESYHTLPHEIVV

MDN1

2671

Q9NU22
SHLISFCLYHTPVTP

MDN1

2971

Q9NU22
SLLYDQPVTSPAHIH

MAP10

406

Q9P2G4
TPIHPVYTSSRGDHL

LETM1

56

O95202
PQIPHQTYSSILKHL

MAPK6

706

Q16659
VAICHPLHYPTILTN

OR51L1

126

Q8NGJ5
PELPITQHTHTLLSY

OR51S1

271

Q8NGJ8
PLLHTVHVLSAYASI

CUL7

136

Q14999
YPQPVAVSHIAHTLS

MNT

511

Q99583
SSHVPYPVALHVNIV

MYB

256

P10242
HVQISYHSSHEPLPL

PADI3

91

Q9ULW8
QHPSTPKRHTVLYIS

NFAT5

131

O94916
YQSLNLTHVPEHSAP

GID4

281

Q8IVV7
ASAIHNPIIYAITHP

OPN4

341

Q9UHM6
SPHYVHSTRSVDISP

FRMD4A

681

Q9P2Q2
TDHLHVTLSVVSYPP

IGSF10

1731

Q6WRI0
IQEHPVVLLPSHRSY

GNPAT

151

O15228
HYSTPLPASLDTTDH

CRTC3

281

Q6UUV7
PSHHYRILNSPVSLA

HUNK

576

P57058
TAPEPHSLGILHASY

ABCG5

31

Q9H222
YSVQSTSPLIHIQHP

DTHD1

361

Q6ZMT9
TSPLIHIQHPSTYPF

DTHD1

366

Q6ZMT9
LPYQDTTIRTHPTLH

MARVELD2

21

Q8N4S9
STLGTAPPTLALHYH

LYL1

91

P12980
AVVASYLHEVQPHSP

KANK4

796

Q5T7N3
LDSPTFHLTLHYPTE

BCAM

251

P50895
SVGVHSAPSSLPYLH

DUSP4

371

Q13115
SIYTIRNHPHPLITV

FOCAD

126

Q5VW36
ASHPTHYDALILVTP

IRGQ

291

Q8WZA9
LLTPVLHHTTEGYPV

PHKB

391

Q93100
HTIPPSLHIIVANLY

OR52N5

276

Q8NH56
HHPSPQEYRLLATTS

FOXN4

21

Q96NZ1
CPESHVPVSLSYHLS

TRMT11

336

Q7Z4G4
TQLIHVYLPLTSHIL

SNX8

401

Q9Y5X2
LYGVTPSLEHPASLH

PRDM14

206

Q9GZV8
LTTTRAHYVPHLPIN

SAXO1

371

Q8IYX7
HGVPRTLSPHQYHSV

TBX5

491

Q99593
VETVYTHVLHPYPTQ

RPN1

131

P04843
THVLHPYPTQITQSE

RPN1

136

P04843
ATETQLPIYTPLTHH

INPP5D

826

Q92835
SPTSQILHTDVVYLH

SRBD1

556

Q8N5C6
ILYRSHNASLHPTPE

RNF213

4381

Q63HN8
YQEHVALHAPISTAP

ZNF618

271

Q5T7W0
IRTYHPPAQLTHTQF

SPEN

3311

Q96T58
SHPLHNDPNLETVYT

MTREX

806

P42285
VTAATYTPGALHPHL

RNF111

816

Q6ZNA4
AYIPDHSHLVRSSVP

SPEM3

356

A0A1B0GUW6
HHLRSPAYSVSTIEP

SLITRK5

826

O94991
HVHPLTPLITYSNEH

TCF7L2

196

Q9NQB0
HVPVSSPLTQHQSYI

ZNF609

1211

O15014
VHAPVLPSTPTHYTL

PIGZ

446

Q86VD9
LPSTPTHYTLLFTHT

PIGZ

451

Q86VD9
IHPTEHSPTYLLIGT

PLEKHH1

766

Q9ULM0
LVHTDHAYQATPPVT

ZNF704

301

Q6ZNC4
HPRQDTYVSTPSEIH

WDR62

776

O43379
SHSHLDAAPLPTVVY

VWA5B2

971

Q8N398
HVSLSLSVHYPPQLL

SIGLEC11

446

Q96RL6
AYIHHPVAVPSESTI

ZNF76

96

P36508
LYSPGHSVLIIITHP

TAS2R4

271

Q9NYW5
TETHVVRSPHPYQLP

TPP1

146

O14773
HTLVSPVQHPYGLTL

LRP4

1246

O75096
YHIPVSSGTPLHLSL

MYRF

1046

Q9Y2G1