Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation activator activity

DAZ1 DAZ3 DAZ4 DAZ2

6.78e-1115114GO:0008494
GeneOntologyMolecularFunctiontranslation regulator activity, nucleic acid binding

DAZ1 DAZ3 DAZ4 DAZ2

3.00e-07112114GO:0090079
GeneOntologyMolecularFunctionmRNA 3'-UTR binding

DAZ1 DAZ3 DAZ4 DAZ2

1.09e-05276114GO:0003730
GeneOntologyMolecularFunctiontranslation regulator activity

DAZ1 DAZ3 DAZ4 DAZ2

6.97e-05443114GO:0045182
GeneOntologyMolecularFunctionmRNA binding

DAZ1 DAZ3 DAZ4 DAZ2

3.93e-04694114GO:0003729
GeneOntologyBiologicalProcessfemale meiosis II

DAZ1 DAZ3 DAZ4 DAZ2

6.56e-136114GO:0007147
GeneOntologyBiologicalProcessmeiosis II

DAZ1 DAZ3 DAZ4 DAZ2

6.56e-136114GO:0007135
GeneOntologyBiologicalProcessmeiosis II cell cycle process

DAZ1 DAZ3 DAZ4 DAZ2

6.56e-136114GO:0061983
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

DAZ1 DAZ3 DAZ4 DAZ2

6.50e-1026114GO:0045836
GeneOntologyBiologicalProcesspositive regulation of translational initiation

DAZ1 DAZ3 DAZ4 DAZ2

1.03e-0929114GO:0045948
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA stabilization

DAZ1 DAZ3 DAZ4 DAZ2

1.37e-0931114GO:0070935
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

DAZ1 DAZ3 DAZ4 DAZ2

2.87e-0937114GO:0051446
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

DAZ1 DAZ3 DAZ4 DAZ2

6.45e-0945114GO:0040020
GeneOntologyBiologicalProcessoocyte maturation

DAZ1 DAZ3 DAZ4 DAZ2

7.72e-0947114GO:0001556
GeneOntologyBiologicalProcessfemale meiotic nuclear division

DAZ1 DAZ3 DAZ4 DAZ2

1.17e-0852114GO:0007143
GeneOntologyBiologicalProcesspositive regulation of nuclear division

DAZ1 DAZ3 DAZ4 DAZ2

5.22e-0875114GO:0051785
GeneOntologyBiologicalProcessmRNA stabilization

DAZ1 DAZ3 DAZ4 DAZ2

5.81e-0877114GO:0048255
GeneOntologyBiologicalProcessregulation of meiotic cell cycle

DAZ1 DAZ3 DAZ4 DAZ2

7.50e-0882114GO:0051445
GeneOntologyBiologicalProcessnegative regulation of mRNA catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

9.53e-0887114GO:1902373
GeneOntologyBiologicalProcessRNA stabilization

DAZ1 DAZ3 DAZ4 DAZ2

9.98e-0888114GO:0043489
GeneOntologyBiologicalProcessregulation of translational initiation

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-0791114GO:0006446
GeneOntologyBiologicalProcesscell maturation

DAZ1 IRX5 DAZ3 DAZ4 DAZ2

1.52e-07267115GO:0048469
GeneOntologyBiologicalProcessoocyte development

DAZ1 DAZ3 DAZ4 DAZ2

1.61e-0799114GO:0048599
GeneOntologyBiologicalProcessnegative regulation of RNA catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

1.74e-07101114GO:1902369
GeneOntologyBiologicalProcessoocyte differentiation

DAZ1 DAZ3 DAZ4 DAZ2

1.88e-07103114GO:0009994
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

DAZ1 DAZ3 DAZ4 DAZ2

2.94e-07115114GO:1903312
GeneOntologyBiologicalProcesspositive regulation of reproductive process

DAZ1 DAZ3 DAZ4 DAZ2

3.26e-07118114GO:2000243
GeneOntologyBiologicalProcesstranslational initiation

DAZ1 DAZ3 DAZ4 DAZ2

5.11e-07132114GO:0006413
GeneOntologyBiologicalProcessanatomical structure maturation

DAZ1 IRX5 DAZ3 DAZ4 DAZ2

6.14e-07354115GO:0071695
GeneOntologyBiologicalProcesspositive regulation of translation

DAZ1 DAZ3 DAZ4 DAZ2

8.75e-07151114GO:0045727
GeneOntologyBiologicalProcessoogenesis

DAZ1 DAZ3 DAZ4 DAZ2

9.97e-07156114GO:0048477
GeneOntologyBiologicalProcessregulation of nuclear division

DAZ1 DAZ3 DAZ4 DAZ2

1.47e-06172114GO:0051783
GeneOntologyBiologicalProcessdevelopmental maturation

DAZ1 IRX5 DAZ3 DAZ4 DAZ2

1.77e-06439115GO:0021700
GeneOntologyBiologicalProcessfemale gamete generation

DAZ1 DAZ3 DAZ4 DAZ2

4.14e-06223114GO:0007292
GeneOntologyBiologicalProcessmeiotic nuclear division

DAZ1 DAZ3 DAZ4 DAZ2

5.53e-06240114GO:0140013
GeneOntologyBiologicalProcessregulation of reproductive process

DAZ1 DAZ3 DAZ4 DAZ2

6.61e-06251114GO:2000241
GeneOntologyBiologicalProcessmeiotic cell cycle process

DAZ1 DAZ3 DAZ4 DAZ2

8.56e-06268114GO:1903046
GeneOntologyBiologicalProcessregulation of mRNA stability

DAZ1 DAZ3 DAZ4 DAZ2

1.20e-05292114GO:0043488
GeneOntologyBiologicalProcesspositive regulation of cell cycle process

DAZ1 DAZ3 DAZ4 DAZ2

1.46e-05307114GO:0090068
GeneOntologyBiologicalProcessregulation of RNA stability

DAZ1 DAZ3 DAZ4 DAZ2

1.48e-05308114GO:0043487
GeneOntologyBiologicalProcessregulation of mRNA catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

1.50e-05309114GO:0061013
GeneOntologyBiologicalProcessmeiotic cell cycle

DAZ1 DAZ3 DAZ4 DAZ2

2.45e-05350114GO:0051321
GeneOntologyBiologicalProcessmRNA catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

3.14e-05373114GO:0006402
GeneOntologyBiologicalProcesspositive regulation of cell cycle

DAZ1 DAZ3 DAZ4 DAZ2

4.42e-05407114GO:0045787
GeneOntologyBiologicalProcessnegative regulation of catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

4.90e-05418114GO:0009895
GeneOntologyBiologicalProcessRNA catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

5.57e-05432114GO:0006401
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

DAZ1 DAZ3 DAZ4 DAZ2

6.15e-05443114GO:1903311
GeneOntologyBiologicalProcessnucleic acid catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

7.36e-05464114GO:0141188
GeneOntologyBiologicalProcessgerm cell development

DAZ1 DAZ3 DAZ4 DAZ2

8.53e-05482114GO:0007281
GeneOntologyBiologicalProcessregulation of translation

DAZ1 DAZ3 DAZ4 DAZ2

9.38e-05494114GO:0006417
GeneOntologyBiologicalProcessnuclear division

DAZ1 DAZ3 DAZ4 DAZ2

1.08e-04512114GO:0000280
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

DAZ1 DAZ3 DAZ4 DAZ2

1.21e-04527114GO:0022412
GeneOntologyBiologicalProcessorganelle fission

DAZ1 DAZ3 DAZ4 DAZ2

1.64e-04571114GO:0048285
GeneOntologyBiologicalProcesspositive regulation of organelle organization

DAZ1 DAZ3 DAZ4 DAZ2

1.68e-04574114GO:0010638
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

DAZ1 IRX5 DAZ3 DAZ4 DAZ2

2.60e-041235115GO:0003006
GeneOntologyBiologicalProcessnucleobase-containing compound catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

3.51e-04696114GO:0034655
GeneOntologyBiologicalProcessregulation of organelle organization

DAZ1 DAZ3 SEC16A DAZ4 DAZ2

3.84e-041342115GO:0033043
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

DAZ1 KIDINS220 DAZ3 DAZ4 DAZ2

4.17e-041366115GO:0051130
GeneOntologyBiologicalProcessspermatogenesis

DAZ1 DAZ3 DAZ4 DAZ2

4.52e-04744114GO:0007283
GeneOntologyBiologicalProcessmale gamete generation

DAZ1 DAZ3 DAZ4 DAZ2

4.95e-04762114GO:0048232
GeneOntologyBiologicalProcesspositive regulation of gene expression

DAZ1 IL17D DAZ3 DAZ4 DAZ2

5.43e-041446115GO:0010628
GeneOntologyBiologicalProcesspositive regulation of protein metabolic process

DAZ1 IL17D DAZ3 DAZ4 DAZ2

5.64e-041458115GO:0051247
GeneOntologyBiologicalProcesstranslation

DAZ1 DAZ3 DAZ4 DAZ2

6.66e-04824114GO:0006412
GeneOntologyBiologicalProcessregulation of cell cycle process

DAZ1 DAZ3 DAZ4 DAZ2

7.33e-04845114GO:0010564
GeneOntologyBiologicalProcessmRNA metabolic process

DAZ1 DAZ3 DAZ4 DAZ2

9.97e-04917114GO:0016071
GeneOntologyBiologicalProcessgamete generation

DAZ1 DAZ3 DAZ4 DAZ2

1.29e-03982114GO:0007276
GeneOntologyBiologicalProcesspost-transcriptional regulation of gene expression

DAZ1 DAZ3 DAZ4 DAZ2

2.33e-031153114GO:0010608
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

DAZ1 DAZ3 DAZ4 DAZ2

2.65e-031194114GO:0048609
GeneOntologyBiologicalProcessregulation of catabolic process

DAZ1 DAZ3 DAZ4 DAZ2

3.16e-031252114GO:0009894
GeneOntologyBiologicalProcessregulation of cell cycle

DAZ1 DAZ3 DAZ4 DAZ2

3.20e-031256114GO:0051726
GeneOntologyBiologicalProcesssexual reproduction

DAZ1 DAZ3 DAZ4 DAZ2

3.75e-031312114GO:0019953
GeneOntologyBiologicalProcessbiomineral tissue development

ODAPH LOX

5.00e-03203112GO:0031214
GeneOntologyBiologicalProcesscell cycle process

DAZ1 DAZ3 DAZ4 DAZ2

5.26e-031441114GO:0022402
GeneOntologyCellularComponentribosome

DAZ1 DAZ3 DAZ4 DAZ2

8.00e-06267114GO:0005840
HumanPhenoOligozoospermia

DAZ1 DAZ3 DAZ4 DAZ2

1.96e-065994HP:0000798
HumanPhenoY-linked inheritance

DAZ1 DAZ3 DAZ2

3.07e-061893HP:0001450
HumanPhenoDecreased testicular size

DAZ1 DAZ3 DAZ4 DAZ2

2.49e-0420094HP:0008734
HumanPhenoMale infertility

DAZ1 DAZ3 DAZ4 DAZ2

2.95e-0420994HP:0003251
HumanPhenoAplasia/Hypoplasia of the testes

DAZ1 DAZ3 DAZ4 DAZ2

3.66e-0422194HP:0010468
HumanPhenoDecreased fertility in males

DAZ1 DAZ3 DAZ4 DAZ2

4.71e-0423694HP:0012041
HumanPhenoAbnormality of the testis size

DAZ1 DAZ3 DAZ4 DAZ2

4.86e-0423894HP:0045058
MousePhenoabsent ovarian follicles

DAZ1 DAZ3 DAZ4 DAZ2

1.95e-085194MP:0002777
MousePhenosmall ovary

DAZ1 DAZ3 DAZ4 DAZ2

3.05e-0617894MP:0001127
MousePhenoabnormal ovarian follicle number

DAZ1 DAZ3 DAZ4 DAZ2

5.14e-0620394MP:0008871
MousePhenoabnormal ovary size

DAZ1 DAZ3 DAZ4 DAZ2

8.15e-0622894MP:0004853
MousePhenoarrest of spermatogenesis

DAZ1 DAZ3 DAZ4 DAZ2

9.82e-0623994MP:0001155
MousePhenoabnormal ovarian follicle morphology

DAZ1 DAZ3 DAZ4 DAZ2

1.08e-0524594MP:0001131
MousePhenoabnormal seminiferous tubule morphology

DAZ1 DAZ3 DAZ4 DAZ2

5.89e-0537794MP:0002216
MousePhenooligozoospermia

DAZ1 DAZ3 DAZ4 DAZ2

6.33e-0538494MP:0002687
MousePhenofemale infertility

DAZ1 DAZ3 DAZ4 DAZ2

8.17e-0541094MP:0001926
MousePhenoabnormal ovary morphology

DAZ1 DAZ3 DAZ4 DAZ2

1.18e-0445194MP:0001126
MousePhenoabnormal female reproductive gland morphology

DAZ1 DAZ3 DAZ4 DAZ2

1.45e-0447594MP:0013324
MousePhenoabnormal sperm number

DAZ1 DAZ3 DAZ4 DAZ2

4.14e-0462494MP:0002673
MousePhenodecreased male germ cell number

DAZ1 DAZ3 DAZ4 DAZ2

4.56e-0464094MP:0004901
MousePhenodecreased germ cell number

DAZ1 DAZ3 DAZ4 DAZ2

5.98e-0468794MP:0002209
MousePhenoabnormal internal female genitalia morphology

DAZ1 DAZ3 DAZ4 DAZ2

8.64e-0475794MP:0009209
MousePhenoabnormal female genitalia morphology

DAZ1 DAZ3 DAZ4 DAZ2

8.90e-0476394MP:0009208
MousePhenoabnormal female reproductive system morphology

DAZ1 DAZ3 DAZ4 DAZ2

9.03e-0476694MP:0001119
MousePhenoabnormal gametes

DAZ1 DAZ3 DAZ4 DAZ2

9.91e-0478594MP:0001124
MousePhenosmall testis

DAZ1 DAZ3 DAZ4 DAZ2

1.18e-0382394MP:0001147
MousePhenoabnormal male germ cell morphology

DAZ1 DAZ3 DAZ4 DAZ2

1.39e-0385994MP:0006362
MousePhenoabnormal female reproductive system physiology

DAZ1 DAZ3 DAZ4 DAZ2

1.50e-0387694MP:0003699
MousePhenosmall gonad

DAZ1 DAZ3 DAZ4 DAZ2

1.55e-0388594MP:0001116
MousePhenoabnormal primary sex determination

DAZ1 DAZ3 DAZ4 DAZ2

1.66e-0390194MP:0002211
MousePhenoabnormal spermatogenesis

DAZ1 DAZ3 DAZ4 DAZ2

1.73e-0391094MP:0001156
MousePhenoabnormal testis size

DAZ1 DAZ3 DAZ4 DAZ2

1.76e-0391594MP:0004849
MousePhenomale infertility

DAZ1 DAZ3 DAZ4 DAZ2

1.98e-0394494MP:0001925
MousePhenoabnormal sex determination

DAZ1 DAZ3 DAZ4 DAZ2

1.99e-0394594MP:0002210
MousePhenoabnormal germ cell morphology

DAZ1 DAZ3 DAZ4 DAZ2

1.99e-0394694MP:0002208
MousePhenoabnormal foam cell morphology

DAZ1 DAZ3 DAZ4 DAZ2

2.06e-0395494MP:0009840
MousePhenoabnormal gametogenesis

DAZ1 DAZ3 DAZ4 DAZ2

3.15e-03107094MP:0001929
MousePhenoabnormal testis morphology

DAZ1 DAZ3 DAZ4 DAZ2

3.27e-03108194MP:0001146
MousePhenoinfertility

DAZ1 DAZ3 DAZ4 DAZ2

4.62e-03118894MP:0001924
MousePhenoabnormal male reproductive gland morphology

DAZ1 DAZ3 DAZ4 DAZ2

6.22e-03129094MP:0013325
MousePhenoabnormal male reproductive system physiology

DAZ1 DAZ3 DAZ4 DAZ2

6.93e-03132994MP:0003698
MousePhenoabnormal internal male genitalia morphology

DAZ1 DAZ3 DAZ4 DAZ2

8.18e-03139294MP:0009205
MousePhenoabnormal male reproductive system morphology

DAZ1 DAZ3 DAZ4 DAZ2

8.68e-03141594MP:0001145
MousePhenoabnormal male genitalia morphology

DAZ1 DAZ3 DAZ4 DAZ2

8.68e-03141594MP:0009198
DomainRRM_1

DAZ1 DAZ3 DAZ4 DAZ2

4.64e-06208114PF00076
DomainRRM

DAZ1 DAZ3 DAZ4 DAZ2

5.49e-06217114SM00360
DomainRRM_dom

DAZ1 DAZ3 DAZ4 DAZ2

6.56e-06227114IPR000504
DomainRRM

DAZ1 DAZ3 DAZ4 DAZ2

6.91e-06230114PS50102
Domain-

DAZ1 DAZ3 DAZ4 DAZ2

8.73e-062441143.30.70.330
DomainNucleotide-bd_a/b_plait

DAZ1 DAZ3 DAZ4 DAZ2

1.09e-05258114IPR012677
PathwayWP_OVARIAN_INFERTILITY

DAZ1 DAZ3 DAZ4 DAZ2

6.61e-0935104MM15948
PathwayWP_MALE_INFERTILITY

DAZ1 DAZ3 DAZ4 DAZ2

2.15e-06145104M39856
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

DAZ1 DAZ3 DAZ4 DAZ2

3.87e-05301104MM15983
PathwayWP_MRNA_PROCESSING

DAZ1 DAZ3 DAZ4 DAZ2

1.86e-04451104MM15946
Pubmed

Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411415066457
Pubmed

Impact of partial DAZ1/2 deletion and partial DAZ3/4 deletion on male infertility.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411426232607
Pubmed

Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411411095434
Pubmed

[Microdeletion of chromosome Y in male infertility: role of the DAZ gene].

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411411688365
Pubmed

Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411411694340
Pubmed

Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411410936047
Pubmed

Polymorphic DAZ gene family in polymorphic structure of AZFc locus: Artwork or functional for human spermatogenesis?

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411412752250
Pubmed

A novel approach for the analysis of DAZ gene copy number in severely idiopathic infertile men.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411411883873
Pubmed

[Study on DAZ gene copy deletion in severe oligozoospermia sperm donor for ICSI].

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411416963411
Pubmed

The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly polymorphic in the DAZ repeat regions.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-1541149321470
Pubmed

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-1541147670487
Pubmed

Polymorphic expression of DAZ proteins in the human testis.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411419223287
Pubmed

Partial DAZ deletions in a family with five infertile brothers.

DAZ1 DAZ3 DAZ4 DAZ2

5.41e-15411412801575
Pubmed

Co-culture of spermatogonial stem cells with sertoli cells in the presence of testosterone and FSH improved differentiation via up-regulation of post meiotic genes.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511423456578
Pubmed

DAZL protein expression in mouse preimplantation embryo.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511417761180
Pubmed

Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451148679003
Pubmed

In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511410903443
Pubmed

A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511410393944
Pubmed

Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511423298641
Pubmed

Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511423579190
Pubmed

The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451148968756
Pubmed

A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451148968755
Pubmed

DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511430380414
Pubmed

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511423223451
Pubmed

Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511434985827
Pubmed

Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511411804965
Pubmed

Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511419468308
Pubmed

Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451149143498
Pubmed

Expression profiling of the developing testis in wild-type and Dazl knockout mice.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511414648873
Pubmed

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511426411291
Pubmed

DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511422223682
Pubmed

Bisphenol A exposure modifies DNA methylation of imprint genes in mouse fetal germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511422699882
Pubmed

A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451148845845
Pubmed

The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451148896558
Pubmed

Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451149700189
Pubmed

Partial rescue of the Dazl knockout mouse by the human DAZL gene.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511412200456
Pubmed

DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511411058556
Pubmed

AZFc partial deletions in Chilean men with severe spermatogenic failure.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511417416365
Pubmed

Dazl promotes germ cell differentiation from embryonic stem cells.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511419783541
Pubmed

Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511422021443
Pubmed

Nature of the spermatogenic arrest in Dazl -/- mice.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511411514340
Pubmed

Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511422293198
Pubmed

Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511421270429
Pubmed

Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511411089564
Pubmed

Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451148661148
Pubmed

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-1451149288969
Pubmed

The dazzle in germ cell differentiation.

DAZ1 DAZ3 DAZ4 DAZ2

2.71e-14511420008336
Pubmed

DAZL binds to the transcripts of several Tssk genes in germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611418452650
Pubmed

The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611432170089
Pubmed

Expression profiles of the DAZ gene family in human testis with and without spermatogenic failure.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611415066460
Pubmed

Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611414611632
Pubmed

DAZL binds to 3'UTR of Tex19.1 mRNAs and regulates Tex19.1 expression.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611419247806
Pubmed

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-1461141869307
Pubmed

A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611417219433
Pubmed

DAZL is a master translational regulator of murine spermatogenesis.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611431355046
Pubmed

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611411390979
Pubmed

The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611423417416
Pubmed

Mono-butyl phthalate-induced mouse testis injury is associated with oxidative stress and down-regulated expression of Sox9 and Dazl.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611428496037
Pubmed

A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611424086306
Pubmed

DAZL regulates Tet1 translation in murine embryonic stem cells.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611426077710
Pubmed

BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611427632217
Pubmed

The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611416001084
Pubmed

Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611416278232
Pubmed

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611432962040
Pubmed

Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611417526644
Pubmed

The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-1461141638086
Pubmed

Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment.

DAZ1 DAZ3 DAZ4 DAZ2

8.12e-14611420157580
Pubmed

Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.

DAZ1 DAZ3 DAZ4 DAZ2

1.89e-13711416946704
Pubmed

Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1.

DAZ1 DAZ3 DAZ4 DAZ2

1.89e-13711410857750
Pubmed

The RNA-binding specificity of the mouse Dazl protein.

DAZ1 DAZ3 DAZ4 DAZ2

1.89e-13711411410654
Pubmed

DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.

DAZ1 DAZ3 DAZ4 DAZ2

1.89e-13711426826184
Pubmed

Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

1.89e-13711415081113
Pubmed

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.

DAZ1 DAZ3 DAZ4 DAZ2

1.89e-13711422699423
Pubmed

Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.

DAZ1 DAZ3 DAZ4 DAZ2

1.89e-13711411604102
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

DAZ1 DAZ3 DAZ4 DAZ2

1.89e-1371149588208
Pubmed

Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811410951504
Pubmed

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811423204224
Pubmed

A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811410823932
Pubmed

Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811429883445
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811422621333
Pubmed

Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811433749946
Pubmed

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811432686646
Pubmed

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811432339196
Pubmed

A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men.

DAZ1 DAZ3 DAZ4 DAZ2

3.79e-13811411869379
Pubmed

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary.

DAZ1 DAZ3 DAZ4 DAZ2

6.82e-13911426378784
Pubmed

Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

6.82e-13911420159962
Pubmed

Embryoid bodies from mouse stem cells express oxytocin receptor, Oct-4 and DAZL.

DAZ1 DAZ3 DAZ4 DAZ2

6.82e-13911419695304
Pubmed

Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.

DAZ1 DAZ3 DAZ4 DAZ2

6.82e-13911416310179
Pubmed

The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.

DAZ1 DAZ3 DAZ4 DAZ2

6.82e-13911428235998
Pubmed

Knockout mouse model and gametogenic failure.

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-12101149922113
Pubmed

Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis.

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-121011431234534
Pubmed

SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60.

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-121011423810942
Pubmed

The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence.

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-121011412837688
Pubmed

Tesmin transcription is regulated differently during male and female meiosis.

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-121011414648882
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-121011410601091
Pubmed

MAX controls meiotic entry in sexually undifferentiated germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-121011438433229
Pubmed

NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells.

DAZ1 DAZ3 DAZ4 DAZ2

1.78e-121111434401671
Pubmed

Retinoic acid activates two pathways required for meiosis in mice.

DAZ1 DAZ3 DAZ4 DAZ2

2.68e-121211425102060
Pubmed

Germ cell-intrinsic and -extrinsic factors govern meiotic initiation in mouse embryos.

DAZ1 DAZ3 DAZ4 DAZ2

2.68e-121211419074348
Pubmed

Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.

DAZ1 DAZ3 DAZ4 DAZ2

2.68e-121211425739037
InteractionPUM2 interactions

DAZ1 DAZ4 DAZ2

5.65e-05144113int:PUM2
CytobandYq11.223

DAZ1 DAZ3 DAZ4 DAZ2

5.15e-0993114Yq11.223
CytobandEnsembl 112 genes in cytogenetic band chrYq11

DAZ1 DAZ3 DAZ4 DAZ2

6.57e-07311114chrYq11
GeneFamilyRNA binding motif containing

DAZ1 DAZ3 DAZ4 DAZ2

6.38e-0721374725
CoexpressionTESAR_JAK_TARGETS_MOUSE_ES_D3_DN

DAZ1 DAZ3 DAZ4 DAZ2

8.29e-1212114MM742
CoexpressionSASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN

DAZ1 DAZ3 DAZ4 DAZ2

8.29e-1212114MM781
CoexpressionWAGSCHAL_EHMT2_TARGETS_UP

DAZ1 DAZ3 DAZ4 DAZ2

1.48e-1023114MM1293
CoexpressionMATZUK_SPERMATOGONIA

DAZ1 DAZ3 DAZ4 DAZ2

5.25e-1031114MM765
CoexpressionCHEN_ETV5_TARGETS_TESTIS

DAZ1 DAZ3 DAZ4 DAZ2

6.83e-1033114MM701
CoexpressionMCCABE_BOUND_BY_HOXC6

DAZ1 PGM2L1 IL17D DAZ3 DAZ4 DAZ2

1.23e-08461116M6376
CoexpressionMADAN_DPPA4_TARGETS

DAZ1 DAZ3 DAZ4 DAZ2

3.50e-0886114MM1312
CoexpressionJACKSON_DNMT1_TARGETS_UP

DAZ1 DAZ3 DAZ4 DAZ2

4.81e-0893114MM1185
CoexpressionGSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_UP

KIDINS220 PGM2L1 SEC16A

3.55e-05160113M7116
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

DAZ1 DAZ3 DAZ4 DAZ2

6.65e-05574114MM820
CoexpressionGSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_UP

KIDINS220 PGM2L1 IL17D

6.80e-05199113M7548
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN

DAZ1 DAZ3 DAZ4 DAZ2

3.90e-04909114M41018
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Cyp26b1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ODAPH IRX5

7.72e-05541124daa84df51cc99113a9f8e86b1ae09bd76a9c991
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Cyp26b1_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ODAPH IRX5

7.72e-05541122e177a9fd0f7c033dbcfa8b41b76658d8268644c
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 IL17D

3.33e-04112112456278fb92dd41820fde8cf27c68fec45e15f972
ToppCelldroplet-Liver-Npc-21m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 LOX

6.35e-04155112d883a3869cf893d62741f26f641ed3923aba03f9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PGM2L1 LOX

7.72e-04171112f047a0cc2ce0a062ec502aa9cb91b1202f437f29
ToppCelldroplet-Liver-Npc-21m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 LOX

8.09e-04175112046e841811b22c39f80a9752f3223c1906de6f20
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

IRX5 IL17D

8.55e-04180112708a5c89b9337e281fce4f482892a1c1766c7812
ToppCelldroplet-Liver-Npc-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 LOX

8.83e-0418311228916f0597690ff534578be2cb715b485cb1de1a
ToppCelldroplet-Liver-Npc-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 LOX

8.83e-0418311299ab7a43527eb226027efbcd8c0b6a8e46fc3c93
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

8.93e-0418411289302321b0949d5b57047b75dd16049aac9a2a3f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ODAPH IRX5

8.93e-041841126b0c110d8930df99043c3b99cf4d873985126960
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ODAPH IRX5

8.93e-0418411235928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IL17D LOX

9.03e-041851122c07991e0907ded67e21ab2e66be21695842ed01
ToppCell390C-Fibroblasts-Fibroblast-F-|390C / Donor, Lineage, Cell class and subclass (all cells)

IL17D LOX

9.03e-0418511237db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCell390C-Fibroblasts-Fibroblast-F|390C / Donor, Lineage, Cell class and subclass (all cells)

IL17D LOX

9.03e-041851122c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IL17D LOX

9.03e-04185112c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IRX5 IL17D

9.22e-0418711208c73d125e0638c9e9878165bba2442c266c8a48
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IRX5 IL17D

9.22e-04187112f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IRX5 IL17D

9.22e-0418711202e7246ef5ad41773d14426254e139b156d45c1d
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

9.32e-041881121a751452c0f1f34b3c20fad2fb52c378ab2d0207
ToppCellMesenchymal_cells-Osteoblasts|World / Lineage and Cell class

IRX5 LOX

9.32e-0418811289f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17D LOX

9.52e-04190112f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCelldroplet-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17D LOX

9.52e-041901122abeb013bb83c578e67dcb985ba44ca63134950b
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17D LOX

9.62e-04191112d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL17D LOX

9.72e-04192112f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IRX5 IL17D

9.72e-04192112d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

9.72e-041921122dee0402e97e48157e0bc01bcc8034f1645dfb7b
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL17D LOX

9.72e-0419211241a8326cd5bc19ad5041068501bab4c72399222e
ToppCellMesenchymal_cells-Ng2+_MSCs|World / Lineage and Cell class

IRX5 LOX

9.72e-041921120703b8ec6960ff975ee5a2737054db67cab016b5
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

PGM2L1 LOX

9.82e-0419311268eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

9.92e-04194112f44394c8a6f86483063f2f5722f003a8a0a70254
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

IRX5 PGM2L1

1.01e-031961120767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PGM2L1 LOX

1.01e-0319611224d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

1.01e-03196112b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.02e-03197112d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.02e-0319711279b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL17D LOX

1.02e-03197112c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.02e-031971122d92b0483d57541aee382dda80e42cf66e813d6b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.02e-031971124961f66606f08e399508fd6cabca588e7ab406a8
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL17D LOX

1.02e-0319711271786e9432e2d649f5d86f639abb25e7102deb67
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.

IRX5 PGM2L1

1.02e-0319711286157ba4f9a40a80bab2404684fe5a7b4ee380c5
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.03e-03198112b73b9feb82997b654718aa27f33ca7b454214802
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.04e-03199112f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL17D LOX

1.04e-031991129672230aa0bc6a7289050c955f5154ca183a5159
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

1.04e-031991129838fed26d8572ac29e7b5fd7220180f734d750a
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.04e-031991120cd3e4e0fba000c996feaf012ff32198e1048c9d
ToppCellNeuron-Postmitotic|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.04e-031991121973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IL17D LOX

1.04e-031991126e8a44e46b46e87b81dbfc56fcbbcde166fd00fe
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

1.04e-03199112e09bd3153dd60d06584707b259c78375b47415c8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.04e-031991125de2a32bc2e9c752eb19a013b1807949153728fc
ToppCellNeuron|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.04e-031991121f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL17D LOX

1.04e-03199112e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.04e-03199112e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.04e-0319911277b4aa00f14b86ef5db0490be98787e063979541
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal|1_mon / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.04e-03199112f94307958cead25d38103fcbb35fa45011de1687
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL17D LOX

1.04e-031991121fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.04e-03199112a255484ba77bd2741a541da278efc8cf4abbe570
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

1.04e-03199112cfe6f881a86607544e1413ef38e4b6797ef1a61c
ToppCelldistal-3-mesenchymal-Adventitial_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IL17D LOX

1.04e-03199112547a7c30abc730af2670aee00c7a6af60426c9ac
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.04e-03199112058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-03200112306926cb7a847871641f02e03d52dc56fd55711c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-0320011284e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

1.05e-03200112ac5843142e0f8a5bcd2c3a784ea13b2f955a32fd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.05e-03200112db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Cortical_neuron|2m / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-03200112db2dbd31dd02c0d1c1070ed5548ce949227e4775
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Cortical_neuron|5w / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-03200112085060d148158f7d9e938b6c4a3700ccbb3bca15
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-03200112979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-032001121decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Cortical_neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-03200112c248233b004f8ef0bab3c65ecfe295887966f2ee
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Interneuron|5w / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-03200112c7e33057466915d4e2b34f2062b22d9cdffa69dc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-0320011219055194a5e0ea122f1b8fc62df44813f6843c95
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal|2m / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-0320011260b86c4a4e247b2673d31b085b440a6e574393bb
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-032001122a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal|3m / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-03200112af99d90070e2933fd2e9512590c6cf3bd6e15539
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron|10w / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-03200112f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PGM2L1 LOX

1.05e-032001125a5d70bfb6d253f272cc1f8516205fcfe8106291
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-0320011268c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Interneuron|2m / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-0320011208bee924a2654e05df3b39e8a51f93c8b3472175
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal|5w / Sample Type, Dataset, Time_group, and Cell type.

KIDINS220 PGM2L1

1.05e-032001129b5753726c17dda98d7384a60f26a5eaf4f6c4d6
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

KIDINS220 PGM2L1

1.05e-0320011230a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
Drugboron trichloride

DAZ1 DAZ3 DAZ4 DAZ2

4.42e-136114CID000025135
Drugdesmethylazelastine

DAZ1 DAZ3 DAZ4 DAZ2

5.35e-1116114CID000162558
Drugdazmegrel

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-1019114CID000053555
DrugYM 026

DAZ1 DAZ3 DAZ4 DAZ2

1.14e-1019114CID000004443
Drugdansylaziridine

DAZ1 DAZ3 DAZ4 DAZ2

2.60e-1023114CID000104008
DrugAZFd

DAZ1 DAZ3 DAZ4 DAZ2

2.60e-1023114CID000196489
DrugBW755C

DAZ1 DAZ3 DAZ4 LOX DAZ2

4.62e-1093115CID000047795
Drugd-gluconhydroximo-1,5-lactam

DAZ1 DAZ3 DAZ4 DAZ2

9.21e-1031114CID000003479
DrugVistar

DAZ1 DAZ3 DAZ4 DAZ2

1.72e-0936114CID000040896
Drug3-bromo-7-nitroindazole

DAZ1 DAZ3 DAZ4 DAZ2

1.72e-0936114CID000001649
Drugmolybdenum disulfide

DAZ1 DAZ3 DAZ4 DAZ2

3.60e-0943114CID000014823
Drug2-chlorodideoxyadenosine

DAZ1 DAZ3 DAZ4 DAZ2

3.60e-0943114CID000072194
Drugpropham

DAZ1 DAZ3 DAZ4 DAZ2

3.96e-0944114CID000024685
Drugridogrel

DAZ1 DAZ3 DAZ4 DAZ2

7.89e-0952114CID005362391
Drugazafagomine

DAZ1 DAZ3 DAZ4 DAZ2

1.15e-0857114CID011957435
DrugNSC56408

DAZ1 DAZ3 DAZ4 DAZ2

1.62e-0862114CID000005604
Drugkt S

DAZ1 DAZ3 DAZ4 DAZ2

2.09e-0866114CID006399216
Drugazelastine

DAZ1 DAZ3 DAZ4 DAZ2

3.33e-0874114CID000002267
Drugp11-13

DAZ1 DAZ3 DAZ4 DAZ2

3.52e-0875114CID000015759
Drugbipy

DAZ1 DAZ3 DAZ4 DAZ2

9.98e-0897114CID000001474
Drugcarbonyl sulfide

DAZ1 DAZ3 DAZ4 DAZ2

2.05e-07116114CID000010039
DrugTXB2 (thromboxane B2

DAZ1 DAZ3 DAZ4 DAZ2

2.20e-07118114CID000005461
Drugthromboxane

DAZ1 DAZ3 DAZ4 DAZ2

2.80e-06223114CID000114873
Drugneocarzinostatin chromophore

DAZ1 DAZ3 DAZ4 DAZ2

7.72e-06288114CID000447545
DrugNSC9700

DAZ1 DAZ3 DAZ4 DAZ2

1.18e-04578114CID000005408
Drug5-aza-2'-deoxycytidine

DAZ1 DAZ3 DAZ4 DAZ2

1.72e-04638114CID000016886
Drug(+/-)-Jasmonic Acid

IRX5 LOX

2.53e-03158112CID000105087
DiseaseMale sterility due to Y-chromosome deletions

DAZ1 DAZ3 DAZ4 DAZ2

7.31e-138114C2931163
DiseasePartial chromosome Y deletion

DAZ1 DAZ3 DAZ4 DAZ2

7.31e-138114C1507149
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

DAZ1 DAZ3 DAZ2

2.15e-0816113C1839071
DiseaseSpermatogenic failure, Y-linked, 2

DAZ1 DAZ3 DAZ2

2.15e-0816113cv:C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

DAZ1 DAZ3 DAZ2

2.15e-0816113415000
Diseaseskin aging measurement

KIDINS220 LOX

1.98e-03181112EFO_0008006
Diseaseurate measurement, bone density

KIDINS220 SEC16A

2.13e-02619112EFO_0003923, EFO_0004531

Protein segments in the cluster

PeptideGeneStartEntry
YQLPVYNYQPFPAYP

DAZ2

206

Q13117
YQLPVYNYQPFPAYP

DAZ3

206

Q9NR90
PLYYTAPFYPGYTNY

IRX5

401

P78411
YNRPFFAPYLYTPRY

KIDINS220

1136

Q9ULH0
YLFSRYVPTPFVPYA

PGM2L1

146

Q6PCE3
YRISYDPARYPRYLP

IL17D

96

Q8TAD2
FQPFYWPHRYLTYRY

ODAPH

101

Q17RF5
YQLPVYNYQPFPAYP

DAZ1

536

Q9NQZ3
NPYYNYYDTYERPRP

LOX

181

P28300
YQLPVYNYQPFPAYP

DAZ4

371

Q86SG3
YYRPLYDAYQPQYSL

SEC16A

1161

O15027