Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessglycoprotein catabolic process

STT3B FBXO2 GUSB CST1 CST4

4.94e-06411265GO:0006516
MousePhenodecreased susceptibility to ischemic brain injury

F12 NBEAL2 CST1 CST4 PLD1

2.52e-05491005MP:0006059
MousePhenodecreased response to brain injury

F12 NBEAL2 CST1 CST4 PLD1

2.52e-05491005MP:0014522
DomainDynein_IC2

DYNC1I1 DYNC1I2

4.37e-0521242PF11540
DomainDYNC1I1/DYNC1I2

DYNC1I1 DYNC1I2

4.37e-0521242IPR025956
DomainWD40

WDHD1 NBEAL2 STRN4 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

5.85e-052591249PF00400
DomainWD40

WDHD1 NBEAL2 STRN4 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

7.60e-052681249SM00320
Domain-

WDHD1 NBEAL2 STRN4 NUP133 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

7.68e-05333124102.130.10.10
DomainWD40/YVTN_repeat-like_dom

WDHD1 NBEAL2 STRN4 NUP133 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

8.07e-0533512410IPR015943
DomainWD40_repeat

WDHD1 NBEAL2 STRN4 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

8.51e-052721249IPR001680
DomainWD_REPEATS_1

WDHD1 NBEAL2 STRN4 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

1.01e-042781249PS00678
DomainWD_REPEATS_2

WDHD1 NBEAL2 STRN4 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

1.03e-042791249PS50082
DomainWD_REPEATS_REGION

WDHD1 NBEAL2 STRN4 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

1.03e-042791249PS50294
DomainWD40_repeat_dom

WDHD1 NBEAL2 STRN4 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

1.65e-042971249IPR017986
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

PRKD2 AMFR CNNM2 RBM26 MTMR10 LUZP1 STT3B CDC37 AP2M1 PTPRS NUP133 TMEM131L ABHD12 WDR77 SDF2 RAB5C SORL1

1.04e-079741271728675297
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ILF2 SYNE1 MYO18A BCAN LUZP1 LONP1 AP2M1 NDUFA12 P2RX3 PTPRS STRN4 USP7 SMARCC2 PEAK1 ABHD12 HSPB1 DYNC1I1 RAB5C RPL18A

1.14e-0614311271937142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

GABRG1 EFCAB5 MYLK SYNE1 MYO18A LUZP1 STT3B MEN1 C2CD3 AP2M1 NDUFA12 YLPM1 STRN4 SMARCC2 NLE1 DYNC1I1 DYNC1I2 RPL18A

5.29e-0614421271835575683
Pubmed

Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human.

DYNC1I1 DYNC1I2

1.32e-052127210049579
Pubmed

DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.

FLT3 DNMT3A

1.32e-052127227300438
Pubmed

[Effect of FLT3-ITD with DNMT3A R882 double-mutation on the prognosis of acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation].

FLT3 DNMT3A

1.32e-052127230122013
Pubmed

DNMT3A R882 Mutation with FLT3-ITD Positivity Is an Extremely Poor Prognostic Factor in Patients with Normal-Karyotype Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation.

FLT3 DNMT3A

1.32e-052127226234722
Pubmed

FLT3-ITD with DNMT3A R882 double mutation is a poor prognostic factor in Chinese patients with acute myeloid leukemia after chemotherapy or allogeneic hematopoietic stem cell transplantation.

FLT3 DNMT3A

1.32e-052127228616699
Pubmed

FLT3-ITD Compared with DNMT3A R882 Mutation Is a More Powerful Independent Inferior Prognostic Factor in Adult Acute Myeloid Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Cohort Study.

FLT3 DNMT3A

1.32e-052127229786546
Pubmed

DNMT3A mutations in acute myeloid leukemia.

FLT3 DNMT3A

1.32e-052127221067377
Pubmed

Exome sequencing reveals DNMT3A and ASXL1 variants associate with progression of chronic myeloid leukemia after tyrosine kinase inhibitor therapy.

ASXL1 DNMT3A

1.32e-052127228667884
Pubmed

Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model.

FLT3 DNMT3A

1.32e-052127227636998
Pubmed

Novel Host Protein TBC1D16, a GTPase Activating Protein of Rab5C, Inhibits Prototype Foamy Virus Replication.

TBC1D16 RAB5C

1.32e-052127234367131
Pubmed

Clinical implication and prognostic significance of FLT3-ITD and ASXL1 mutations in Egyptian AML patients: A single-center study.

ASXL1 FLT3

1.32e-052127234487021
Pubmed

DNMT3A co-mutation is required for FLT3-ITD as an adverse prognostic indicator in intermediate-risk cytogenetic group AML.

FLT3 DNMT3A

1.32e-052127229165010
Pubmed

The stability of epigenetic factor ASXL1 is regulated through ubiquitination and USP7-mediated deubiquitination.

ASXL1 USP7

1.32e-052127225836587
Pubmed

Mouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcripts.

DYNC1I1 DYNC1I2

1.32e-052127220657784
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ILF2 MYO18A PACSIN3 LUZP1 STT3B FAM83B CDC37 AP2M1 HELZ2 NUP133 USP7 NLE1 WDR77 HSPB1 RAB5C RPL18A

1.46e-0512571271636526897
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MYO18A LRP1B STT3B LONP1 AP2M1 NDUFA12 CPT1C STRN4 USP7 SMARCC2 PEAK1 ABHD12 CNOT2 HSPB1 RPL18A

1.86e-0511391271536417873
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

ASXL1 SYNE1 PACSIN3 FAM83B BCLAF3 AP2M1 LIN37 YLPM1 STRN4 NUP133 SMARCC2 WDR77 CNOT2 DYNC1I2 RAB5C

2.18e-0511551271520360068
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

ILF2 CDC37 LONP1 WDHD1 NUP133 USP7 WDR77 HSPB1 DYNC1I2 RAB5C RPL18A

2.37e-056381271133239621
Pubmed

Defining the membrane proteome of NK cells.

AMFR ILF2 MYO18A LUZP1 STT3B ZDHHC20 LONP1 GUSB NBEAL2 HELZ2 NUP133 PLD1 FUT7 CNOT2 RPL18A

2.48e-0511681271519946888
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

ILF2 RBM26 WDHD1 USP7 SMARCC2 HSPB1 RAB5C RPL18A

3.76e-05340127824332808
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

KRT27 PACSIN3 F12 SULT2B1 PTPRS GUSB HPN HSP90AB2P FIGNL1 STK24 KRT25 HSPB1 RAB5C ALOX15B

3.85e-0510701271423533145
Pubmed

Telomere Attrition and Clonal Hematopoiesis of Indeterminate Potential in Cardiovascular Disease.

ASXL1 DNMT3A

3.96e-053127234576030
Pubmed

Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.

FAM83B PLD1

3.96e-053127223912460
Pubmed

DNMT3A (R882) mutation features and prognostic effect in acute myeloid leukemia in Coexistent with NPM1 and FLT3 mutations.

FLT3 DNMT3A

3.96e-053127229079128
Pubmed

Combined heterozygosity of FLT3 ITD, TET2, and DNMT3A results in aggressive leukemia.

FLT3 DNMT3A

3.96e-053127236073548
Pubmed

Low frequency of mutations in Chinese with acute myeloid leukemia: Different disease or different aetiology?

FLT3 DNMT3A

3.96e-053127225858894
Pubmed

Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry.

CST1 CST4

3.96e-05312721898352
Pubmed

Clinical Effect of Combined Mutations in DNMT3A, FLT3-ITD, and NPM1 Among Egyptian Acute Myeloid Leukemia Patients.

FLT3 DNMT3A

3.96e-053127230926392
Pubmed

Immunofluorescence localization of cystatins in human lacrimal gland and in the exorbital lacrimal gland of the rat.

CST1 CST4

3.96e-05312721471486
Pubmed

Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response.

FLT3 DNMT3A

3.96e-053127235122024
Pubmed

Measurable residual disease of canonical versus non-canonical DNMT3A, TET2, or ASXL1 mutations in AML at stem cell transplantation.

ASXL1 DNMT3A

3.96e-053127234267355
Pubmed

Prognostic Impact of Concurrent DNMT3A, FLT3 and NPM1 Gene Mutations in Acute Myeloid Leukemia Patients.

FLT3 DNMT3A

3.96e-053127234376373
Pubmed

[Relationship between DTA Mutations and Thromboembolism in Patients with Myeloproliferative Neoplasms].

ASXL1 DNMT3A

3.96e-053127238926973
Pubmed

Epigenetic Changes in Neoplastic Mast Cells and Potential Impact in Mastocytosis.

ASXL1 DNMT3A

3.96e-053127233803981
Pubmed

Clinical features and prognostic significance of DNMT3A, FLT3, and NPM1 mutations in de novo acute myeloid leukemia patients.

FLT3 DNMT3A

3.96e-053127237519024
Pubmed

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.

FLT3 DNMT3A

3.96e-053127227016502
Pubmed

Prognostic Relevance of DNMT3A, FLT3 and NPM1 Mutations in Syrian Acute Myeloid Leukemia Patients.

FLT3 DNMT3A

3.96e-053127235485701
Pubmed

Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations.

FLT3 DNMT3A

3.96e-053127223603912
Pubmed

K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.

KRT27 KRT25

3.96e-053127216874310
Pubmed

IDH mutations are closely associated with mutations of DNMT3A, ASXL1 and SRSF2 in patients with myelodysplastic syndromes and are stable during disease evolution.

ASXL1 DNMT3A

3.96e-053127224115220
Pubmed

Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S.

CST1 CST4

3.96e-05312721778989
Pubmed

Clonal haematopoiesis of indeterminate potential and atrial fibrillation: an east Asian cohort study.

ASXL1 DNMT3A

3.96e-053127238231881
Pubmed

HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults.

ASXL1 DNMT3A

3.96e-053127234099923
Pubmed

Clinical features of de novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations.

FLT3 DNMT3A

3.96e-053127225281355
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

AMFR CNNM2 ILF2 SYNE1 CDC37 LONP1 YLPM1 STRN4 PEAK1 RPL18A

5.09e-055731271028330616
Pubmed

Human transcription factor protein interaction networks.

ASXL1 HNF1A ILF2 MYO18A CDC37 LONP1 AP2M1 LIN37 YLPM1 USP7 SMARCC2 FOXP1 CNOT2 ZNF121 SORL1 RPL18A

6.76e-0514291271635140242
Pubmed

A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.

SYNE1 FBXO2 DYNC1I1 DYNC1I2

7.06e-0560127420682791
Pubmed

Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.

KRT27 KRT25

7.90e-054127217920809
Pubmed

Mutation analysis of JAK2V617F, FLT3-ITD, NPM1, and DNMT3A in Chinese patients with myeloproliferative neoplasms.

FLT3 DNMT3A

7.90e-054127224895580
Pubmed

Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo.

FLT3 DNMT3A

7.90e-054127234903841
Pubmed

Molecular cloning, chromosome mapping and characterization of a testis-specific cystatin-like cDNA, cystatin T.

CST1 CST4

7.90e-054127210713450
Pubmed

Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.

CST1 CST4

7.90e-054127213679380
Pubmed

Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors.

GABRG1 CRHR2

7.90e-054127215001778
Pubmed

Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.

PRKD2 RAB5C

7.90e-054127222734003
Pubmed

Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

ASXL1 DNMT3A

7.90e-054127222905207
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SYTL2 RBM26 STT3B CDC37 AP2M1 MEX3A WDHD1 GUSB YLPM1 TMEM131L CNOT2

8.23e-057331271134672954
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

ILF2 CDC37 NUP133 USP7 SMARCC2 HSP90AB2P HSPB1 DYNC1I2 RPL18A

8.82e-05494127926831064
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

ASXL1 FBXO2 MEN1 CDC37 LIN37 CST4 USP7 HSPB1 SENP7

8.96e-05495127927705803
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

AMFR CNNM2 MYO18A SMOC1 STT3B AP2M1 USP7 ABHD12 SDF2 DYNC1I2 RAB5C

1.06e-047541271133060197
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SYNE1 RBM26 PACSIN3 LUZP1 STT3B FAM83B MEN1 NDUFA12 ELAPOR1 STRN4 HELZ2 USP7 HSP90AB2P WDR77 CNOT2 RAB5C

1.16e-0414971271631527615
Pubmed

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.

MYLK LONP1 NDUFA12 NUP133 USP7 SMARCC2 RCN3 RPL18A

1.22e-04403127835253629
Pubmed

Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking.

DYNC1I1 DYNC1I2

1.31e-045127225015291
Pubmed

Role of cystatin C in amyloid precursor protein-induced proliferation of neural stem/progenitor cells.

CST1 CST4

1.31e-045127223671283
Pubmed

Cystatin C stimulates the differentiation of mouse osteoblastic cells and bone formation.

CST1 CST4

1.31e-045127217592728
Pubmed

Obesity-Induced Increase in Cystatin C Alleviates Tissue Inflammation.

CST1 CST4

1.31e-045127232616516
Pubmed

The epimorphin gene is highly conserved among humans, mice, and rats and maps to human chromosome 7, mouse chromosome 5, and rat chromosome 12.

HNF1A GUSB

1.31e-04512728938452
Pubmed

Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice.

CST1 CST4

1.31e-045127234440840
Pubmed

Transforming growth factor beta regulates cystatin C in serum-free mouse embryo (SFME) cells.

CST1 CST4

1.31e-04512722241983
Pubmed

Strong conservation of the expression of cystatin C gene in choroid plexus.

CST1 CST4

1.31e-04512721636787
Pubmed

Cooperating gene mutations in childhood acute myeloid leukemia with special reference on mutations of ASXL1, TET2, IDH1, IDH2, and DNMT3A.

ASXL1 DNMT3A

1.31e-045127223365461
Pubmed

Gene deletion of cystatin C aggravates brain damage following focal ischemia but mitigates the neuronal injury after global ischemia in the mouse.

CST1 CST4

1.31e-045127215450354
Pubmed

Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development.

CST1 CST4

1.31e-045127221443774
Pubmed

Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis.

CST1 CST4

1.31e-045127227079462
Pubmed

Decreased metastatic spread in mice homozygous for a null allele of the cystatin C protease inhibitor gene.

CST1 CST4

1.31e-045127210748866
Pubmed

Absence of the protease inhibitor cystatin C in inflammatory cells results in larger plaque area in plaque regression of apoE-deficient mice.

CST1 CST4

1.31e-045127215823274
Pubmed

Mutations of the epigenetics-modifying gene (DNMT3a, TET2, IDH1/2) at diagnosis may induce FLT3-ITD at relapse in de novo acute myeloid leukemia.

FLT3 DNMT3A

1.31e-045127223135354
Pubmed

Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2.

FLT3 DNMT3A

1.31e-045127227435003
Pubmed

Cystatin C deficiency promotes epidermal dysplasia in K14-HPV16 transgenic mice.

CST1 CST4

1.31e-045127221085595
Pubmed

Hypoxic vasodilatory defect and pulmonary hypertension in mice lacking hemoglobin β-cysteine93 S-nitrosylation.

CST1 CST4

1.31e-045127234914637
Pubmed

A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cells.

CST1 CST4

1.31e-045127216595632
Pubmed

Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.

DYNC1I1 DYNC1I2

1.31e-045127230250299
Pubmed

Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation.

CST1 CST4

1.31e-045127220489058
Pubmed

Neuroprotection mediated by cystatin C-loaded extracellular vesicles.

CST1 CST4

1.31e-045127231367000
Pubmed

Up-regulation of cystatin C expression in the murine hippocampus following perforant path transections.

CST1 CST4

1.31e-045127212044447
Pubmed

FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor.

CST1 CST4

1.31e-045127211144350
Pubmed

Mouse and rat cystatin C: Escherichia coli production, characterization and tissue distribution.

CST1 CST4

1.31e-04512728761177
Pubmed

Cystatin C triggers neuronal degeneration in a model of multiple system atrophy.

CST1 CST4

1.31e-045127224405769
Pubmed

Overexpression of human cystatin C in transgenic mice does not affect levels of endogenous brain amyloid Beta Peptide.

CST1 CST4

1.31e-045127214742906
Pubmed

Cystatin C is released in association with exosomes: a new tool of neuronal communication which is unbalanced in Alzheimer's disease.

CST1 CST4

1.31e-045127219773092
Pubmed

PKD, PKD2, and p38 MAPK mediate Hsp27 serine-82 phosphorylation induced by neurotensin in pancreatic cancer PANC-1 cells.

PRKD2 HSPB1

1.31e-045127217570131
Pubmed

Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis.

CST1 CST4

1.31e-045127233754041
Pubmed

Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system.

CST1 CST4

1.31e-045127224570004
Pubmed

Loss of cystatin C regulates permeability and inflammatory pathways in retina.

CST1 CST4

1.31e-045127236822364
Pubmed

Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice.

CST1 CST4

1.31e-045127232467129
Pubmed

Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse.

CST1 CST4

1.31e-045127216242633
Pubmed

Carminerin contributes to chondrocyte calcification during endochondral ossification.

CST1 CST4

1.31e-045127216680148
Pubmed

Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis.

CST1 CST4

1.31e-045127233027652
Cytoband20p11.21

CST1 CST4 ABHD12

1.06e-0433127320p11.21
CytobandEnsembl 112 genes in cytogenetic band chr19q13

LYPD4 PRKD2 ZFP28 ZNF600 LIN37 ZNF497 SULT2B1 CPT1C HPN STRN4 ZNF766 RCN3

1.24e-04119212712chr19q13
GeneFamilyWD repeat domain containing

WDHD1 NBEAL2 STRN4 NLE1 WDR90 WDR77 PHIP DYNC1I1 DYNC1I2

7.48e-06262929362
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 SYNE1 SYTL2 MAST4 SENP7 ZNF121 DNMT3A

8.26e-0819212783b0a52e4e77ae4539a034dcb419773b8e2aa5d51
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 SYNE1 SYTL2 MAST4 SENP7 ZNF121

1.12e-061871277cfdc1585c80d2bb475d9145395fb50a88c53f838
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 SYNE1 SYTL2 MAST4 SENP7 ZNF121

1.34e-06192127797c312c82ec025c13052f8d424b11c0034c8ea54
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYTL2 FAM83B ST6GALNAC5 RCN3 ALOX15B KLB

5.36e-0615412762d98bb7a784fc3215e0d4a1670d662e5df4716c3
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYTL2 FAM83B ST6GALNAC5 RCN3 ALOX15B KLB

5.36e-0615412760dec222101530f1727184dbb7c03969d3884f111
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYTL2 LRP1B ST6GALNAC5 KRT25 RCN3 KLB

7.17e-061621276ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA3 FAM83B MEX3A GSTT4 PRDM12

9.11e-06981275ffe21b3681fdeaf4a8447bd2b13772d03cdd45aa
ToppCellNS-critical-d_16-33-Epithelial-Basal|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TPO SMOC1 PNCK HSPB1 ALOX15B RPL18A

1.04e-0517312763d3afc9ab234eaabf5b9bff455406231cd54ded6
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ABCA3 PACSIN3 FBXO2 PTPRS HPN KLB

1.08e-051741276110369f6b78de34a6d934b5b47cecd023347bc80
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CNNM2 LRP1B FOXP1 SENP7 ZNF121 DNMT3A

1.31e-051801276cf7d8bf9eee2dfab2c8a6780e296b05ad42041bf
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 MAST4 LPAR6 FUT7 SENP7 ZNF121

1.53e-051851276e34473eea3a58c041183a4f52137366cd9489495
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 SYNE1 MAST4 SENP7 ZNF121

1.62e-051871276b426a67b5669019115b58295ce7d304beeb75825
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CNNM2 MAST4 FOXP1 SENP7 ZNF121 RPL18A

1.67e-0518812762b630b0609d4ac61338d6533cb7893cfe1241e44
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 MAST4 SENP7 ZNF121 RPL18A

1.77e-0519012767179f980f895d3e5b839b5ae26b5c991787bfe3a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 SYNE1 MAST4 SENP7 ZNF121

1.77e-051901276600b9674197f743dea1d19d3df0fc993b6e6aa25
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 SYNE1 MAST4 SENP7 ZNF121

1.88e-051921276c5f77c2103841505d13e09173549811312ef2f01
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 SYNE1 MAST4 SENP7 ZNF121

1.88e-051921276e981162f387a31111c0ae8355dbe9db5785c4838
ToppCell10x5'-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

FLT3 ENOX1 SMOC1 CBFA2T3 PTPRS FUT7

1.99e-051941276768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCellNS-moderate-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SULT2B1 PTPRS LPAR6 ELAPOR1 HSPB1 SORL1

2.11e-0519612765d5f3c3e9052b7cdca442e39e73b16ca27a16657
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NTMT2 ITGA10 SMOC1 LRP1B FBXO2 CORIN

2.24e-051981276c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCellTracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NTMT2 ITGA10 SMOC1 LRP1B FBXO2 CORIN

2.24e-05198127655f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ILF2 BCAN SMOC1 AP2M1 MEX3A PTPRS

2.30e-05199127659915b6db86fd0cc83a0bf9a3a1dda08522ec8d3
ToppCellmLN-(5)_Dendritic_cell-(54)_pDC|mLN / shred on region, Cell_type, and subtype

HNF1A FLT3 CDH23 BCAN PTPRS FUT7

2.30e-0519912761e738219784a446ee8b0ddeb408e0050e1929e60
ToppCellmLN-Dendritic_cell-pDC|mLN / Region, Cell class and subclass

HNF1A FLT3 CDH23 BCAN PTPRS FUT7

2.30e-05199127654f1abb57af7bf8a8b82a38b933f257df3b5d8df
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 ITGA10 LRP1B FBXO2 CORIN DYNC1I1

2.37e-052001276b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 ITGA10 LRP1B FBXO2 CORIN DYNC1I1

2.37e-052001276f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PACSIN3 CDH23 BCAN TBC1D16 ZNF600 HELZ2

2.37e-052001276be1abe5bb1ce4e7dfec63af4ed0fc5b96bf77866
ToppCellCiliated_cells-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

HNF1A CFAP100 FNDC11 TTC29 TTLL10

1.02e-0416212755319603f7ba3f48126dcf2ba9ae604be11bf2577
ToppCellAdult-Immune-dendritic_cell|Adult / Lineage, Cell type, age group and donor

DENND5B FLT3 ENOX1 SMOC1 CBFA2T3

1.11e-041651275073f52698dac1fe4edd7410865f81b30e1c7196a
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

1.20e-041681275dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellHealthy_Control-Lymphoid-pDC|Healthy_Control / Condition, Lineage, Cell class and cell subclass

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

1.24e-041691275a4e9b8b2f0338203455ba941b8f99bf4884d26f0
ToppCellHealthy_Control-Lymphoid-pDC-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

1.24e-041691275338ce99897cb522b86edd603f75bc15ec4dfcda3
ToppCellImmune-dendritic_cell|World / Lineage, Cell type, age group and donor

DENND5B FLT3 ENOX1 SMOC1 CBFA2T3

1.31e-0417112756a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 F12 NBEAL2 FUT7 ALOX15B

1.34e-041721275c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 F12 NBEAL2 FUT7 ALOX15B

1.34e-041721275953b05f776348cff784e79c93df65841939d880f
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PACSIN3 PTPRS HPN ALOX15B KLB

1.38e-041731275ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EFCAB5 FLT3 CBFA2T3 MEX3A RPL18A

1.38e-041731275b6aed736d8480e3a6a5718aabd2fb79b1b75fa48
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK ITGA10 LRP1B MEX3A PNCK

1.46e-041751275d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK ITGA10 LRP1B MEX3A PNCK

1.46e-041751275cf15465855602ba135752c18755e3e058dbd42ec
ToppCellDendritic_Cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FLT3 SMOC1 CBFA2T3 LPAR6 FUT7

1.54e-041771275d2cd081bdda0eba9f6f6473c4d3939e4bee3440e
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

MYLK DELEC1 BCAN PTPRS ST6GALNAC5

1.54e-0417712758220cc2fc0ee8764a67a3be51d75248be2453040
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel-D175|Adult / Lineage, Cell type, age group and donor

MYO18A LRP1B LUZP1 ARL17A NLE1

1.54e-041771275c9f269765c7d5d29caab75910e51645606ed562e
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

MYLK DELEC1 BCAN PTPRS ST6GALNAC5

1.54e-0417712757617270f49cd6b7ba66db72d20560cee985012b2
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS ST6GALNAC5 FUT7 RCN3 ALOX15B

1.54e-041771275c1f838e425ebb04482829b1957e3c1347127e6de
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS ST6GALNAC5 FUT7 RCN3 ALOX15B

1.58e-041781275cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP100 FNDC11 TTC29 TTLL10 AGBL2

1.58e-041781275255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNDC11 TTC29 CST1 ELAPOR1 KLB

1.62e-041791275d70791d2a0db35a6b013fa7ed2f9f39364581eff
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP1 CYB5RL CDH23 BCLAF3 NBEAL2

1.62e-04179127508cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DENND5B FLT3 CBFA2T3 PTPRS FUT7

1.66e-041801275144818e69613296cde43f29cb8c20899c670b319
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

ENOX1 CFAP100 TTC29 TTLL10 AGBL2

1.75e-0418212757ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B FAM83B MAST4 ST6GALNAC5 DNMT3A

1.75e-041821275041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMFR SMOC1 F12 HPN KLB

1.79e-041831275d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

FAM83B PTPRS PNCK PLD1 DYNC1I1

1.84e-041841275ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMFR EVC FBXO2 TBC1D16 SULT2B1

1.89e-0418512756da9a06e1514d5d5f47359a14637f02539846096
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 CNNM2 SYNE1 SENP7 ZNF121

1.89e-0418512750382bfbc96c23403b18fe439d8070ea9a7d29fd2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMFR EVC FBXO2 TBC1D16 SULT2B1

1.89e-0418512754a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPD4 SYNE1 SYTL2 MAST4 SENP7

1.93e-041861275facc1bd8920003ad03d1893c32fc606d82b4d50a
ToppCellMultiple_Sclerosis-Myeloid-pDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

1.93e-041861275330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF600 LPAR6 ELAPOR1 HELZ2 DNMT3A

1.93e-04186127577bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JADE3 ST6GALNAC5 ELAPOR1 RCN3 KLB

1.93e-0418612754bb54043f944a979db91bde9a86dd66f498c7658
ToppCell10x5'-Liver-Myeloid_Dendritic-DC1|Liver / Manually curated celltypes from each tissue

FLT3 ENOX1 MYLK SMOC1 CBFA2T3

1.93e-041861275e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF600 LPAR6 ELAPOR1 HELZ2 DNMT3A

1.93e-04186127513bc41c60fd628af31899a5e8b480e06cc4781be
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA3 GANC MAST4 HPN ALOX15B

1.98e-0418712755df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SMOC1 AP2M1 MEX3A PTPRS DYNC1I1

1.98e-04187127585645de9069bd9a8a02d53b0d3d73bf9c2b57189
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GALNAC5 ELAPOR1 KLHDC8B RCN3 KLB

2.03e-041881275e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCellPBMC-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

2.03e-04188127589411c4db3df5e1dc36cf8af4ffcc0abbecbe4df
ToppCelltumor_Lung-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

FLT3 BCAN CBFA2T3 FUT7 RPL18A

2.03e-0418812759874ba56bf6a0d509cccc89563dbf1395e17e84e
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

MYLK SYNE1 ITGA10 CBFA2T3 STK24

2.03e-0418812751aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellPBMC-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

2.03e-041881275de6a270b6e4fe09c39a52c296632d86ada98465b
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVC SMOC1 CFAP100 HPN PLD1

2.03e-041881275842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVC SMOC1 CFAP100 HPN PLD1

2.03e-041881275a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCellPBMC-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

2.03e-041881275879054b780378ae05be68e597c77c931bf0ade03
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLT3 CDH23 CBFA2T3 PTPRS FUT7

2.03e-0418812751f820cb19eb0e15f0eb69d07e457072bbdad8ecb
ToppCellPBMC-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

2.08e-041891275209cae68d78c8f72479b169e27c3ff7e143adece
ToppCellPBMC-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

2.08e-041891275a9ad1fb12304541f909dd0eeac9b9eb28c31fd41
ToppCellCOVID-19_Mild-Myeloid-pDC|COVID-19_Mild / Disease group, lineage and cell class

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

2.08e-041891275c6cfd6aa21c19f2c62d80218bbc924e14e82aada
ToppCellPBMC-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLT3 SMOC1 CBFA2T3 PTPRS FUT7

2.08e-04189127598ca646231fbd5f29827c2dd31ac4503026bad7d
ToppCellCOVID-19_Mild-Treg|COVID-19_Mild / Disease condition and Cell class

ASXL1 MAST4 LPAR6 FOXP1 FUT7

2.08e-041891275f0fceb5f87ca260bfe038c0db3487a6d2e1b0a6e
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLT3 CDH23 CBFA2T3 PTPRS FUT7

2.14e-041901275c44aae2e0d3cc84a187e12917fd8c2d7483f41d8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SMOC1 ST6GALNAC5 TMEM131L CORIN DYNC1I1

2.14e-041901275562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCelldroplet-Kidney-nan-21m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK CRHR2 TTC29 PNCK KLHDC8B

2.14e-041901275e04f47705851563515b6a66a2634cf7a574f7bda
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SMOC1 ST6GALNAC5 TMEM131L CORIN DYNC1I1

2.14e-041901275f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLT3 CDH23 CBFA2T3 PTPRS FUT7

2.14e-041901275705489ebbaf3d8e643498c3e507742114475fc55
ToppCellSevere-MAIT|Severe / Disease group and Cell class

NRIP1 SYTL2 ZFP28 PLD1 SORL1

2.14e-0419012751c063dc1b62d9f9912aaf8d0297555a6545f5550
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B FLT3 SMOC1 CBFA2T3 PTPRS

2.19e-041911275989bf108c7f2c78dd7f14481570f1819673a5469
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SMOC1 MEX3A ST6GALNAC5 TMEM131L DYNC1I1

2.19e-041911275509d17d8ee0d028757ce0f2c9b97e5875f06f0ab
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B FLT3 SMOC1 CBFA2T3 PTPRS

2.19e-0419112753e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B FLT3 SMOC1 CBFA2T3 PTPRS

2.19e-041911275bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCellCOVID-19-Lymphoid-pDC|COVID-19 / Condition, Lineage and Cell class

DENND5B FLT3 SMOC1 CBFA2T3 PTPRS

2.19e-04191127525343b11d42128ad16659e5519cd1673266cc505
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DENND5B FLT3 SMOC1 CBFA2T3 PTPRS

2.24e-041921275d9ff2293358c8b031ba212021012e058014ff472
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CNNM2 MAST4 FOXP1 SENP7 ZNF121

2.24e-04192127532927ef3b93e0497e9bbe63c2754da03cf178202
ToppCellSevere_COVID-19-Myeloid-pDC|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DENND5B FLT3 SMOC1 CBFA2T3 PTPRS

2.24e-041921275f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DENND5B FLT3 SMOC1 CBFA2T3 PTPRS

2.24e-0419212752e8611d65090e39f1a6e74c972288e7b68376d15
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DENND5B FLT3 SMOC1 CBFA2T3 PTPRS

2.24e-04192127543569726df281eebe57499e0993b9fd9d36118c2
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK SMOC1 HSPB1 RCN3 GABRA3

2.30e-0419312759a2c1711dec9dd8c8313bcf25bb888ac8e86c3f3
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK SMOC1 HSPB1 RCN3 GABRA3

2.30e-0419312757c7aa5e2124830d0fa1df11b6413ec6cf780aad0
ToppCellVE-pDC-|VE / Condition, Cell_class and T cell subcluster

FLT3 CDH23 SMOC1 CBFA2T3 PTPRS

2.30e-041931275583724de588fcde3aeda056138c522dc0225a387
ToppCell10x5'-Lung-Myeloid_Dendritic|Lung / Manually curated celltypes from each tissue

FLT3 ENOX1 SMOC1 CBFA2T3 PTPRS

2.30e-0419312757bce609699c515d2d114596a0c527f90cc09c4af
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-22|World / Primary Cells by Cluster

ALPK1 MEX3A ELAPOR1 SORL1 RPL18A

2.30e-0419312753b927d4b8ecb21a408424ef91a23746c21741f49
ToppCellVE-pDC|VE / Condition, Cell_class and T cell subcluster

FLT3 CDH23 SMOC1 CBFA2T3 PTPRS

2.30e-041931275bb759dc9ef0ec41d655002f59021d62d62d44289
Diseaseduodenal ulcer

FLT3 CBFA2T3 CORIN PLD1

1.48e-05361224EFO_0004607
DiseaseWoolly hair, congenital

LPAR6 KRT25

1.68e-0451222C0345427
DiseaseProlactinoma

CDH23 MEN1

2.52e-0461222C0033375
DiseaseWooly hair

LPAR6 KRT25

3.51e-0471222C0343073
Diseasecystatin-SA measurement

CST1 CST4

4.67e-0481222EFO_0008105
Diseasecystatin-SN measurement

CST1 CST4

5.99e-0491222EFO_0008106
Diseasealcohol consumption measurement

GABRG1 HNF1A ALPK1 STT3B MAST4 ST6GALNAC5 FOXP1 WDR90 PEAK1 AGBL2 STK24 SENP7 SORL1 KLB

6.30e-04124212214EFO_0007878
Diseasealpha fetoprotein measurement

HNF1A AGAP11 SENP7 KLB

8.03e-041001224EFO_0010583
Diseasegastroesophageal reflux disease

NRIP1 YLPM1 FOXP1 STK24

8.34e-041011224EFO_0003948
Diseaseselective IgA deficiency disease

CDH23 MAST4 FOXP1

9.19e-04461223EFO_1001929
DiseaseAcute Promyelocytic Leukemia

ASXL1 FLT3 DNMT3A

9.19e-04461223C0023487
Diseaselysophosphatidylcholine 15:0 measurement

LRP1B TTC29

1.49e-03141222EFO_0020941
Diseaseresponse to platinum based chemotherapy, magnesium measurement

NTMT2 TBC1D16

1.72e-03151222EFO_0004647, EFO_0004845
Diseasenervousness

YLPM1 AGBL2

1.96e-03161222NCIT_C74532
Diseasemood instability measurement

LRP1B YLPM1 AGBL2 STK24

2.00e-031281224EFO_0008475
Diseaseresponse to radiation, Urinary retention

LRP1B PTPRS

2.21e-03171222GO_0009314, HP_0000016
Diseasecystatin-D measurement

CST1 CST4

2.21e-03171222EFO_0008103
DiseaseAcute myeloid leukemia

FLT3 DNMT3A

2.21e-03171222cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

FLT3 DNMT3A

2.21e-03171222601626
Diseaseischemia (implicated_via_orthology)

CRHR2 LONP1

2.21e-03171222DOID:326 (implicated_via_orthology)
Diseasebitter alcoholic beverage consumption measurement

AGBL2 SENP7 SORL1 KLB

2.30e-031331224EFO_0010092
Diseaseforced expiratory volume, response to bronchodilator

PRKD2 SYNE1 DELEC1 LRP1B MAST4 TTC29 TXNRD3

2.57e-034451227EFO_0004314, GO_0097366
DiseaseColorectal Carcinoma

ABCA3 SYNE1 CBFA2T3 SULT2B1 PTPRS TTLL10 PHIP RAB5C SORL1

2.61e-037021229C0009402
DiseaseIntellectual Disability

SYNE1 STT3B AP2M1 SMARCC2 PHIP DYNC1I2 DNMT3A

2.63e-034471227C3714756
DiseaseJuvenile Myelomonocytic Leukemia

ASXL1 DNMT3A

2.77e-03191222C0349639
Diseasetaurocholate measurement

SMOC1 FOXP1

3.07e-03201222EFO_0010538
Diseaseethylmalonate measurement

HNF1A CBFA2T3

3.07e-03201222EFO_0020009
DiseasePrecursor B-cell lymphoblastic leukemia

FLT3 FOXP1

3.38e-03211222C1292769
Diseaseobsolete_red blood cell distribution width

NRIP1 ASXL1 HNF1A FLT3 CDH23 SMOC1 CBFA2T3 ARL17A LONP1 MAST4 YLPM1 HELZ2 PLD1

3.85e-03134712213EFO_0005192

Protein segments in the cluster

PeptideGeneStartEntry
HFKATTYEERDAWVQ

AGAP11

286

Q8TF27
DAKEVSAAHRARYFW

DNMT3A

781

Q9Y6K1
ALQYQHERRASDWAV

ABCA3

856

Q99758
NTFAVWDVGSHFKIR

ARL17A

61

Q8IVW1
DYEEVHWLNFTVRAS

CDH23

2361

Q9H251
EFFTHAAQSWRERLA

ASXL1

311

Q8IXJ9
RRNWTHSDAFRVSLD

ALPK1

536

Q96QP1
QRHIRDSVSAAWDTY

RCN3

111

Q96D15
NRFIKVYWHREGSTQ

RBM26

596

Q5T8P6
KFEIWDTAGQERYHS

RAB5C

71

P51148
WNSLSRSYFKDRAHI

MEN1

126

O00255
DNKQFFGRHRWVVYT

NDUFA12

51

Q9UI09
TYDALHVFDWIKARS

ABHD12

221

Q8N2K0
KHFSTRRSWEEAETQ

BCAN

701

Q96GW7
DSSEKHAYSWDINRA

NUP133

301

Q8WUM0
SRSVHLSEWQKNYFA

FIGNL1

6

Q6PIW4
VWFKDDQSIRESRHF

MYLK

1841

Q15746
RRLYWADENHIEFSN

LRP1B

3186

Q9NZR2
WKEASHRNQLRYSES

LIN37

221

Q96GY3
NTRWLEYVRAFLKHS

MTMR10

371

Q9NXD2
KHNRTWDLEFSLYEA

NLRP10

556

Q86W26
TNDWKDHLAVRYFSV

HSP90AB2P

231

Q58FF8
WAFQRTTFHEASRKY

ELAPOR1

551

Q6UXG2
NRQFYDEHWSKHRVV

DYNC1I1

276

O14576
SLNRQFFDERWSKHR

DYNC1I2

266

Q13409
FLRNWRIESYLNDHS

FAM83B

491

Q5T0W9
ERDHWQQFYFLSKRR

FBXO2

106

Q9UK22
WERDYNTKRVDHSNT

PCNX1

1521

Q96RV3
RKQFARHEWAQKAAY

MYO18A

686

Q92614
AHFQKSSAIRYQEVW

PEAK1

521

Q9H792
AHWSADAVYQEARKV

TPO

426

P07202
SQHRDYITEKFWRNA

FUT7

231

Q11130
HTEGKRYFTWDKNRF

GANC

401

Q8TET4
YFRRNAATWKNAVRH

FOXP1

501

Q9H334
YHRDLARWEAAQASK

CYB5RL

41

Q6IPT4
FFNGEVRSAVRKRWH

CRHR2

361

Q13324
NRRDAEAWFNEKSAS

KRT27

271

Q7Z3Y8
NRRDAEAWFNEKSAS

KRT25

266

Q7Z3Z0
RYITHESDDARWEQF

PRKD2

826

Q9BZL6
SEHRSWARESKSFNV

NRIP1

921

P48552
NWFANRRKEEAFRHK

HNF1A

266

P20823
HSSEFNVTRNYLDWL

LONP1

451

P36776
EATASRFRAVAFHNW

LYPD4

31

Q6UWN0
VFFRQTWHDERLKFD

GABRA3

116

P34903
TADRWRVSLDVNHFA

HSPB1

91

P04792
NWSVRRSDFRFSEVH

LPAR6

306

P43657
ARTSFFHVKRSNIWL

AP2M1

51

Q96CW1
VRYFIDASQEDHRSW

PRDM12

146

Q9H4Q4
LNHWARRYSDAEDTK

CBFA2T3

431

O75081
FREWIFQAIKTHSEA

HPN

396

P05981
RNSTNFFKDRHWTTR

METTL6

51

Q8TCB7
FFKDRHWTTREFEEL

METTL6

56

Q8TCB7
SSEKREVRQFQFTAW

PTPRS

1541

Q13332
NFARTHWKRAFNATS

PNCK

291

Q6P2M8
HDRWFDKSFTLIVFS

CPT1C

446

Q8TCG5
HRTWTEIFKEHNFSF

FLT3

711

P36888
DEYIRDHSRTEVWKF

EFCAB5

1436

A4FU69
ARARVDEFVAWQHTA

GSTT4

91

A0A1W2PR19
QRSIADSFRFEGKWH

BCLAF3

156

A2AJT9
NTFWRHDTKADTRAI

C2CD3

386

Q4AC94
PDTFFRNSRKSDAHW

GABRG1

146

Q8N1C3
RRWDDSQKYLSDNVH

CDC37

166

Q16543
FTDALHRERSVKWQA

DELEC1

31

Q9P2X7
VFDRKASAAHQDWAR

FNDC11

211

Q9BVV2
SSFNDISQDWRLRHF

GUSB

81

P08236
RHARWFEENASQSTV

ILF2

206

Q12905
SARIFHKNVFIWDFI

DENND5B

1141

Q6ZUT9
HTQWFYFRVQNTRKD

AGBL2

301

Q5U5Z8
AEHQRAFRDYTTWKL

CFAP100

121

Q494V2
YFGHRTQKEASISWE

CORIN

476

Q9Y5Q5
GFSDARHVTVRNAWK

LUZP1

911

Q86V48
EVKQHRFFRSLDWNS

MAST4

836

O15021
RWDHQFYMRFTASLD

ITGA10

691

O75578
AFEAFDLEARTWTRH

KLHDC8B

191

Q8IXV7
SHWRAAERFLQFEIA

KLB

756

Q86Z14
HKAFWQEAERFSREF

EVC

426

P57679
ISKDNSWRFYSRHKT

CCDC168

6451

Q8NDH2
DEWVQRALHFAISEY

CST1

41

P01037
ERKTQYSWTFAVHSE

HELZ2

176

Q9BYK8
DEWVQRALHFAISEY

CST4

41

P01036
AVFNASTRQKAWDHF

ENOX1

351

Q8TC92
HFSRSFKETTNRWVK

JADE3

711

Q92613
FRSQAHRDFVRDATW

WDR77

291

Q9BQA1
WVFLHEKAYQVRDTA

P2RX3

41

P56373
TLEKAWHAFFTAAER

PACSIN3

76

Q9UKS6
YIWLASEKAHERQRA

MROH5

591

Q6ZUA9
AKTWVRNAEFSFHEA

ALOX15B

356

O15296
AHFAFRSRWQKTDDE

NTMT2

6

Q5VVY1
LRFFHKNEIWYRTEQ

F12

141

P00748
LSIWHRDTFKRNSFL

SYTL2

716

Q9HCH5
YSASQDRTIKVWRAH

NLE1

261

Q9NVX2
VRTWTRHINIFNKDY

SENP7

836

Q9BQF6
NLFWAFDTHKQERRT

SORL1

1781

Q92673
WKNHFTVAQSEAFDR

SULT2B1

281

O00204
WEGQAASKSFRHRVS

SYNE1

3241

Q8NF91
WYRNHFDRSVVLNDV

TMEM131L

411

A2VDJ0
RDVARHFIQRWNFTK

PLD1

691

Q13393
DRYKRWKAEQSHDDS

STK24

301

Q9Y6E0
SDRQFHSVAAAWQAR

NBEAL2

2191

Q6ZNJ1
KRVFKNWARTFNIHF

ST6GALNAC5

301

Q9BVH7
NHVVAKSRFWYFVSQ

RPL18A

36

Q02543
AWFDYNSVHAIERRA

SMARCC2

431

Q8TAQ2
YWVRDGEVRFKHSST

SDF2

141

Q99470
ERFTYHNVRLWDEES

SSH3

371

Q8TE77
RVSERQHLKDKFWNF

AMFR

111

Q9UKV5
NNETWSRIAFTEHER

CNNM2

111

Q9H8M5
AVELFNRDWRYHKEE

CNOT2

461

Q9NZN8
ERVVHWYFSQLDSNS

SMOC1

361

Q9H4F8
RWFYLDDSEEKVHNR

ZFP28

381

Q8NHY6
NFHYRKQTKDQWARD

UNC50

66

Q53HI1
NVFRHFRVDEWKRSA

WDR90

11

Q96KV7
AFSWNSNFLEHRRVH

ZNF497

226

Q6ZNH5
FWTNELTDTRAKFHV

ZDHHC20

196

Q5W0Z9
WEVRYIEHNTRTFNE

PHIP

1226

Q8WWQ0
AAIDSRYSDAWRVHQ

MEX3A

311

A1L020
EAYFWLRQNTDEHAR

STT3B

586

Q8TCJ2
KLYRRESWSHQFDLS

WDHD1

211

O75717
EHRAFWRNVQFTVDK

TBC1D16

476

Q8TBP0
DRVRHFDQFWSAAKT

YLPM1

1936

P49750
NVHQRTWIGDKSFEY

ZNF121

76

P58317
NNSEDKWVRNHFYER

TTC29

151

Q8NA56
DSRKFGWEYNQQVRH

TXNRD3

226

Q86VQ6
FIQHEWARFEAEKAR

STRN4

71

Q9NRL3
KVFRHSSWFVQHQRS

ZNF766

446

Q5HY98
DTAFTWNSQLARHKR

ZNF600

336

Q6ZNG1
EHLNRYISDTFWKAR

TTLL10

441

Q6ZVT0
SRRISHLFFHKENDW

USP7

151

Q93009
FRFHERTQTHKNALW

ZNF439

481

Q8NDP4