Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsupercoiled DNA binding

HMGB1 HMGB2

2.44e-056262GO:0097100
GeneOntologyMolecularFunctionRAGE receptor binding

HMGB1 HMGB2

1.69e-0415262GO:0050786
GeneOntologyMolecularFunctionfour-way junction DNA binding

HMGB1 HMGB2

2.75e-0419262GO:0000400
GeneOntologyMolecularFunctionDNA binding, bending

HMGB1 HMGB2

3.05e-0420262GO:0008301
GeneOntologyMolecularFunctiontau-protein kinase activity

TAOK2 TAOK1

3.71e-0422262GO:0050321
GeneOntologyMolecularFunctiontranscription coactivator activity

BIRC2 HMGB1 HMGB2 KMT2C

5.97e-04303264GO:0003713
GeneOntologyMolecularFunctiontranscription coregulator activity

BIRC2 HMGB1 HMGB2 KMT2C PARP14

6.99e-04562265GO:0003712
GeneOntologyMolecularFunctionprotein kinase activator activity

TAOK2 HMGB1 TAOK1

9.33e-04149263GO:0030295
GeneOntologyMolecularFunctionkinase activator activity

TAOK2 HMGB1 TAOK1

1.13e-03159263GO:0019209
GeneOntologyMolecularFunctionDNA secondary structure binding

HMGB1 HMGB2

1.30e-0341262GO:0000217
GeneOntologyMolecularFunctionstructural constituent of muscle

NEB MYBPC1

1.42e-0343262GO:0008307
GeneOntologyMolecularFunctiontau protein binding

TAOK2 TAOK1

1.63e-0346262GO:0048156
GeneOntologyMolecularFunctionenzyme regulator activity

TAOK2 BIRC2 HMGB1 TAOK1 SERPINB13 RHOU SERPINB2

1.78e-031418267GO:0030234
GeneOntologyMolecularFunctionchemoattractant activity

HMGB1 HMGB2

2.24e-0354262GO:0042056
GeneOntologyMolecularFunctionpentosyltransferase activity

POGLUT1 PARP14

2.40e-0356262GO:0016763
GeneOntologyMolecularFunctionprotein kinase regulator activity

TAOK2 HMGB1 TAOK1

4.50e-03259263GO:0019887
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

TAOK2 TAOK1

4.61e-0378262GO:0043539
GeneOntologyMolecularFunctiondamaged DNA binding

HMGB1 HMGB2

5.32e-0384262GO:0003684
GeneOntologyMolecularFunctionmyosin binding

TAOK1 MYBPC1

5.45e-0385262GO:0017022
GeneOntologyMolecularFunctionkinase regulator activity

TAOK2 HMGB1 TAOK1

7.07e-03305263GO:0019207
GeneOntologyMolecularFunctionserine-type endopeptidase inhibitor activity

SERPINB13 SERPINB2

8.20e-03105262GO:0004867
GeneOntologyCellularComponentdendritic growth cone

TAOK2 COBL

9.74e-0512262GO:0044294
GeneOntologyCellularComponentdendrite terminus

TAOK2 COBL

2.79e-0420262GO:0044292
GeneOntologyCellularComponentaxonal growth cone

TAOK2 COBL

1.43e-0345262GO:0044295
MousePhenofailure of neuromuscular synapse postsynaptic differentiation

UTP14C UTP14A

3.53e-056222MP:0001055
DomainSSU_processome_Utp14

UTP14C UTP14A

1.86e-062262IPR006709
DomainUtp14

UTP14C UTP14A

1.86e-062262PF04615
DomainHMG_boxA_CS

HMGB1 HMGB2

5.59e-063262IPR017967
DomainHMG_box

HMGB1 HMGB2 KMT2C

5.36e-0553263PF00505
DomainHMG

HMGB1 HMGB2 KMT2C

5.67e-0554263SM00398
DomainHMG_box_2

HMGB1 HMGB2

6.67e-059262PF09011
DomainHMG_BOX_1

HMGB1 HMGB2

8.33e-0510262PS00353
DomainHMG_box_dom

HMGB1 HMGB2 KMT2C

9.88e-0565263IPR009071
DomainSerpin_CS

SERPINB13 SERPINB2

9.01e-0432262IPR023795
DomainSerpin_dom

SERPINB13 SERPINB2

1.14e-0336262IPR023796
DomainSERPIN

SERPINB13 SERPINB2

1.20e-0337262PS00284
DomainSERPIN

SERPINB13 SERPINB2

1.20e-0337262SM00093
DomainSerpin

SERPINB13 SERPINB2

1.27e-0338262PF00079
DomainSerpin_fam

SERPINB13 SERPINB2

1.34e-0339262IPR000215
DomainHMG_BOX_2

HMGB1 HMGB2

2.55e-0354262PS50118
Domain-

HMGB1 HMGB2

2.64e-03552621.10.30.10
PathwayREACTOME_APOPTOTIC_EXECUTION_PHASE

BIRC2 HMGB1 HMGB2

5.80e-0549223MM15448
PathwayREACTOME_APOPTOTIC_EXECUTION_PHASE

BIRC2 HMGB1 HMGB2

6.94e-0552223M2341
PathwayBIOCARTA_DNAFRAGMENT_PATHWAY

HMGB1 HMGB2

1.04e-0410222M7239
PathwayBIOCARTA_DNAFRAGMENT_PATHWAY

HMGB1 HMGB2

1.27e-0411222MM1349
PathwayREACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION

HMGB1 HMGB2

1.52e-0412222MM14554
PathwayREACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION

HMGB1 HMGB2

1.79e-0413222M1018
PathwayREACTOME_APOPTOSIS

BIRC2 HMGB1 HMGB2

6.06e-04108223MM14471
PathwayPID_P38_MKK3_6PATHWAY

TAOK2 TAOK1

7.39e-0426222M20
PathwayREACTOME_PROGRAMMED_CELL_DEATH

BIRC2 HMGB1 HMGB2

1.34e-03142223MM15178
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

NEB MYBPC1

1.34e-0335222MM15005
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

NEB MYBPC1

1.42e-0336222M18647
PathwayWP_STRIATED_MUSCLE_CONTRACTION_PATHWAY

NEB MYBPC1

1.58e-0338222M39549
Pubmed

Stimulation of spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mutant mice by gonadotropin-releasing hormone antagonist treatment.

UTP14C UTP14A

5.37e-07226210499552
Pubmed

Testosterone suppresses spermatogenesis in juvenile spermatogonial depletion (jsd ) mice.

UTP14C UTP14A

5.37e-07226211466222
Pubmed

Cloning and analysis of an HMG gene from the lamprey Lampetra fluviatilis: gene duplication in vertebrate evolution.

HMGB1 HMGB2

5.37e-0722629016958
Pubmed

Anti-high mobility group box 1 and box 2 non-histone chromosomal proteins (HMGB1/HMGB2) antibodies and anti-Saccharomyces cerevisiae antibodies (ASCA): accuracy in differentially diagnosing UC and CD and correlation with inflammatory bowel disease phenotype.

HMGB1 HMGB2

5.37e-07226222644337
Pubmed

shRNA off-target effects in vivo: impaired endogenous siRNA expression and spermatogenic defects.

UTP14C UTP14A

5.37e-07226225790000
Pubmed

Defect in germ cells, not in supporting cells, is the cause of male infertility in the jsd mutant mouse: proliferation of spermatogonial stem cells without differentiation.

UTP14C UTP14A

5.37e-07226211168646
Pubmed

Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.

TAOK2 TAOK1

5.37e-07226228830982
Pubmed

Association of HMGB1 and HMGB2 genetic polymorphisms with lung cancer chemotherapy response.

HMGB1 HMGB2

5.37e-07226224684392
Pubmed

Properties of Human Embryonic Stem Cells and Their Differentiated Derivatives Depend on Nonhistone DNA-Binding HMGB1 and HMGB2 Proteins.

HMGB1 HMGB2

5.37e-07226227863459
Pubmed

Conformational difference in HMGB1 proteins of human neutrophils and lymphocytes revealed by epitope mapping of a monoclonal antibody.

HMGB1 HMGB2

5.37e-07226215496585
Pubmed

Evidence for a shared structural role for HMG1 and linker histones B4 and H1 in organizing chromatin.

HMGB1 HMGB2

5.37e-0722628599938
Pubmed

Cryptorchidism rescues spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mice.

UTP14C UTP14A

5.37e-07226214500567
Pubmed

The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures.

HMGB1 HMGB2

5.37e-0722628339930
Pubmed

cDNA sequence and structure of a trout HMG-2 gene. Evidence for a trout-specific 3'-untranslated region.

HMGB1 HMGB2

5.37e-0722627607539
Pubmed

Non-histone chromosomal proteins HMG1 and 2 enhance ligation reaction of DNA double-strand breaks.

HMGB1 HMGB2

5.37e-0722629600082
Pubmed

Testosterone inhibits spermatogonial differentiation in juvenile spermatogonial depletion mice.

UTP14C UTP14A

5.37e-07226211415997
Pubmed

HMGB proteins and arthritis.

HMGB1 HMGB2

5.37e-07226228916968
Pubmed

Restoration of spermatogenesis and fertility in azoospermic mutant mice by suppression and reelevation of testosterone followed by intracytoplasmic sperm injection.

UTP14C UTP14A

5.37e-07226211751268
Pubmed

Involvement of high mobility group B proteins in cisplatin-induced cytotoxicity in squamous cell carcinoma of skin.

HMGB1 HMGB2

5.37e-07226219435426
Pubmed

The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer.

HMGB1 HMGB2

5.37e-07226238542079
Pubmed

Recent integrations of mammalian Hmg retropseudogenes.

HMGB1 HMGB2

5.37e-07226217406091
Pubmed

The combination of a nuclear HMGB1-positive and HMGB2-negative expression is potentially associated with a shortened survival in patients with pancreatic ductal adenocarcinoma.

HMGB1 HMGB2

5.37e-07226225060178
Pubmed

Overexpression of high mobility group (HMG) B1 and B2 proteins directly correlates with the progression of squamous cell carcinoma in skin.

HMGB1 HMGB2

5.37e-07226218798064
Pubmed

Cessation of spermatogenesis in juvenile spermatogonial depletion (jsd/jsd) mice.

UTP14C UTP14A

5.37e-0722629354954
Pubmed

Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2.

HMGB1 HMGB2

5.37e-07226211262228
Pubmed

Loss of sperm in juvenile spermatogonial depletion (jsd) mutant mice is ascribed to a defect of intratubular environment to support germ cell differentiation.

UTP14C UTP14A

5.37e-0722621346141
Pubmed

Correlation of serum HMGB1 and HMGB2 levels with clinical symptoms in allergic rhinitis children.

HMGB1 HMGB2

5.37e-07226237713866
Pubmed

Nonhistone Proteins HMGB1 and HMGB2 Differentially Modulate the Response of Human Embryonic Stem Cells and the Progenitor Cells to the Anticancer Drug Etoposide.

HMGB1 HMGB2

5.37e-07226233076532
Pubmed

Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes.

HMGB1 HMGB2

5.37e-07226212925773
Pubmed

Interactions of HMGB Proteins with the Genome and the Impact on Disease.

HMGB1 HMGB2

5.37e-07226234680084
Pubmed

The HMG-1 box protein family: classification and functional relationships.

HMGB1 HMGB2

5.37e-0722627784217
Pubmed

Androgen suppression-induced stimulation of spermatogonial differentiation in juvenile spermatogonial depletion mice acts by elevating the testicular temperature.

UTP14C UTP14A

5.37e-07226221733828
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

HMGB1 ATG4C HMGB2 EMC2 NEB TM9SF3 MYBPC1 UTP14C UTP14A

5.82e-07144226935575683
Pubmed

Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids.

UTP14C UTP14A

1.61e-0632628529672
Pubmed

Juvenile spermatogonial depletion (jsd): a genetic defect of germ cell proliferation of male mice.

UTP14C UTP14A

1.61e-0632623401545
Pubmed

Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades.

TAOK2 TAOK1

1.61e-0632629786855
Pubmed

Gene expression alterations by conditional knockout of androgen receptor in adult sertoli cells of Utp14b(jsd/jsd) (jsd) mice.

UTP14C UTP14A

1.61e-06326220650881
Pubmed

Identification of the core-histone-binding domains of HMG1 and HMG2.

HMGB1 HMGB2

1.61e-0632623697355
Pubmed

Genetic factors contributing to defective spermatogonial differentiation in juvenile spermatogonial depletion (Utp14bjsd) mice.

UTP14C UTP14A

1.61e-06326217475932
Pubmed

TAO kinases mediate activation of p38 in response to DNA damage.

TAOK2 TAOK1

1.61e-06326217396146
Pubmed

The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b.

UTP14C UTP14A

1.61e-06326215289605
Pubmed

The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2.

HMGB1 HMGB2

1.61e-06326210490593
Pubmed

Spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mice with androgen receptor or follicle-stimulating hormone mutations.

UTP14C UTP14A

1.61e-06326216627582
Pubmed

An X-to-autosome retrogene is required for spermatogenesis in mice.

UTP14C UTP14A

1.61e-06326215258580
Pubmed

High mobility group proteins stimulate DNA cleavage by apoptotic endonuclease DFF40/CAD due to HMG-box interactions with DNA.

HMGB1 HMGB2

1.61e-06326218239742
Pubmed

Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.

TAOK2 TAOK1

1.61e-06326223585562
Pubmed

Androgen receptor in Sertoli cells is not required for testosterone-induced suppression of spermatogenesis, but contributes to Sertoli cell organization in Utp14b jsd mice.

UTP14C UTP14A

1.61e-06326219136388
Pubmed

Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.

HMGB1 HMGB2

1.61e-06326231621076
Pubmed

Arrest of spermatogonial differentiation in jsd/jsd, Sl17H/Sl17H, and cryptorchid mice.

UTP14C UTP14A

1.61e-06326210456866
Pubmed

A novel RAG1 mutation reveals a critical in vivo role for HMGB1/2 during V(D)J recombination.

HMGB1 HMGB2

1.61e-06326230538136
Pubmed

High mobility group proteins 1 and 2 can function as DNA-binding regulatory components for DNA-dependent protein kinase in vitro.

HMGB1 HMGB2

1.61e-0632629722660
Pubmed

Utp14b: a unique retrogene within a gene that has acquired multiple promoters and a specific function in spermatogenesis.

UTP14C UTP14A

1.61e-06326217291484
Pubmed

Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.

UTP14C UTP14A

1.61e-06326230910870
Pubmed

Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells.

UTP14C UTP14A

3.22e-0642627924983
Pubmed

Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway.

UTP14C UTP14A

3.22e-06426211900972
Pubmed

The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB.

HMGB1 HMGB2

3.22e-06426214739282
Pubmed

A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucleoside analogues.

HMGB1 HMGB2

3.22e-06426212517784
Pubmed

Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular proteins.

HMGB1 HMGB2

3.22e-06426211099378
Pubmed

Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain.

TAOK2 TAOK1

3.22e-06426210497253
Pubmed

HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoter.

HMGB1 HMGB2

3.22e-06426211748232
Pubmed

UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man.

UTP14C UTP14A

3.22e-06426216354793
Pubmed

Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.

TAOK2 TAOK1

5.37e-06526213679851
Pubmed

HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha.

HMGB1 HMGB2

5.37e-06526219223331
Pubmed

High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells.

HMGB1 HMGB2

5.37e-0652629671457
Pubmed

Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex.

TAOK2 TAOK1

5.37e-06526222683681
Pubmed

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.

HMGB1 HMGB2

5.37e-06526219890330
Pubmed

Mapping of genes for inhibin subunits alpha, beta A, and beta B on human and mouse chromosomes and studies of jsd mice.

UTP14C UTP14A

5.37e-0652622767687
Pubmed

p53-dependent apoptosis in the inhibition of spermatogonial differentiation in juvenile spermatogonial depletion (Utp14bjsd) mice.

UTP14C UTP14A

8.05e-06626218356279
Pubmed

Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis.

HMGB1 HMGB2

8.05e-06626219139395
Pubmed

Identification of a novel Sry-related gene and its germ cell-specific expression.

UTP14C UTP14A

8.05e-06626210359848
Pubmed

The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability.

TAOK2 TAOK1

8.05e-06626212639963
Pubmed

Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway.

UTP14C UTP14A

8.05e-06626215938716
Pubmed

Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription.

UTP14C UTP14A

8.05e-06626211733032
Pubmed

Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways.

TAOK2 TAOK1

8.05e-06626216893890
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

HMGB1 HMGB2 UTP14C UTP14A

8.88e-0617726426206133
Pubmed

In vitro acetylation of HMGB-1 and -2 proteins by CBP: the role of the acidic tail.

HMGB1 HMGB2

1.13e-05726215005629
Pubmed

Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus.

SERPINB13 SERPINB2

2.94e-051126215203215
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

COBL KMT2C ZNF106 TAOK1 NEB

3.00e-0549726536774506
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

TAOK2 KMT2C POGLUT1 NEB SIGLEC8 MYBPC1 UTP14A

3.41e-05129326715342556
Pubmed

Molecular diversity of myofibrillar proteins: gene regulation and functional significance.

NEB MYBPC1

3.53e-05122628618961
Pubmed

Identification and sequencing the juvenile spermatogonial depletion critical interval on mouse chromosome 1 reveals the presence of eight candidate genes.

UTP14C UTP14A

4.17e-051326211700028
Pubmed

An 'equalized cDNA library' by the reassociation of short double-stranded cDNAs.

UTP14C UTP14A

4.17e-05132622216762
Pubmed

Human transcription factor protein interaction networks.

MRPL4 HMGB1 HMGB2 KMT2C ESS2 KLF10 UTP14A

6.44e-05142926735140242
Pubmed

Identification of casein kinase Ialpha interacting protein partners.

HMGB1 HMGB2

7.26e-051726212062430
Pubmed

Mouse models of male infertility.

UTP14C UTP14A

7.26e-051726212360237
Pubmed

Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.

SERPINB13 SERPINB2

7.26e-051726219690890
Pubmed

A functional screen to identify novel effectors of hematopoietic stem cell activity.

HMGB1 KLF10

7.26e-051726219379700
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MRPL4 BIRC2 HMGB1 ESS2 EMC2 TM9SF3 UTP14A

8.59e-05149626732877691
Pubmed

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression.

BIRC2 KLF10 SERPINB2

9.59e-0511926324162774
Pubmed

HMGB factors are required for posterior digit development through integrating signaling pathway activities.

HMGB1 HMGB2

1.23e-042226221384471
Pubmed

The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response.

HMGB1 HMGB2

1.47e-042426232867128
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

HMGB1 KMT2C TAOK1 ESS2 KLF10 UTP14A

1.49e-04112426621900206
Pubmed

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.

UTP14C UTP14A

1.73e-042626235920200
Pubmed

Spermatogonia-dependent expression of testicular genes in mice.

UTP14C UTP14A

2.15e-042926212051830
Pubmed

Isolation and characterization of proteins associated with histone H3 tails in vivo.

HMGB1 KMT2C

2.31e-043026217403666
Pubmed

Analysis of the Tropism of SARS-CoV-2 Based on the Host Interactome of the Spike Protein.

HMGB1 HMGB2

2.47e-043126237939376
Pubmed

Interaction proteomics of the HMGA chromatin architectural factors.

HMGB1 HMGB2

2.63e-043226218850631
Pubmed

Cellular substrates and pro-apoptotic function of the human HtrA4 protease.

COBL HMGB2 TAOK1

2.89e-0417326331470122
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

MRPL4 HMGB1 TAOK1 ESS2 TM9SF3 UTP14A

3.51e-04131826630463901
Pubmed

Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages.

HMGB1 HMGB2

3.52e-043726234225486
InteractionCDC42 interactions

TAOK2 BIRC2 COBL HMGB1 TAOK1 EMC2 RHOU TM9SF3 SERPINB2

1.72e-051323259int:CDC42
InteractionUTP14C interactions

HMGB1 UTP14C UTP14A

3.18e-0550253int:UTP14C
CytobandEnsembl 112 genes in cytogenetic band chr18q21

SERPINB13 SERPINB2

6.01e-03205262chr18q21
GeneFamilyCanonical high mobility group

HMGB1 HMGB2

7.02e-0511212511
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

TAOK2 TAOK1

3.49e-0424212654
GeneFamilySerpin peptidase inhibitors

SERPINB13 SERPINB2

8.35e-0437212739
CoexpressionONDER_CDH1_TARGETS_1_DN

POGLUT1 SERPINB13 KLF10 UTP14C UTP14A SERPINB2

1.09e-08170256M6822
CoexpressionGSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN

MRPL4 BIRC2 EMC2 PARP14

3.67e-05200254M3664
ToppCellMonocytes-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

HMGB2 NEB UTP14A

1.64e-0585263e73603d6f22bb56159aa5d1a2695775f038e61d8
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

COBL NEB MYBPC1

9.84e-05155263d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Batf3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COBL KLF10 RHOU

1.02e-04157263921805932f7974d37aed547861d555b07f30aba6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COBL KLF10 RHOU

1.41e-04175263c227fc5d1ccb69b82a96a6354913cafaf27d0eec
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COBL RHOU MYBPC1

1.48e-04178263c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

KMT2C TAOK1 PARP14

1.61e-041832638f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

KMT2C TAOK1 PARP14

1.74e-04188263ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HMGB2 KLF10 PARP14

1.77e-04189263cce6602ad68c177985a5e43cfb2776d615cfbca0
ToppCellBAL-Severe-Myeloid-MoAM-MoAM5-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HMGB2 KLF10 SERPINB2

1.91e-04194263c53478057674d70b79df8a3f476d15dea1925753
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

KMT2C KLF10 PARP14

1.91e-04194263d1366b169d14011194e61d16b6b0953349febc78
ToppCellBAL-Severe-Myeloid-MoAM-MoAM5-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HMGB2 KLF10 SERPINB2

1.91e-041942638805c90e4284a81a6c8078f2d2417ae77b4e5c63
ToppCellBAL-Severe-Myeloid-MoAM-MoAM5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HMGB2 KLF10 SERPINB2

1.91e-0419426386d52467b05a0018517377c9c441245501f71d91
ToppCellBAL-Severe-Myeloid-MoAM-MoAM5|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HMGB2 KLF10 SERPINB2

1.91e-041942632ab3f75b795a0ee4fe0f8eeba33093fcc77935f5
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Pro-B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HMGB1 HMGB2 TAS2R43

1.91e-041942633590ff471f74a361ee5bf02a58e3104cd3bf7d00
ToppCellSevere_COVID-19-Myeloid-MoAM5|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

HMGB2 KLF10 SERPINB2

1.94e-041952636d768454ed630e586431535400507074eea76dd1
ToppCellfacs-Trachea-3m|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TAOK1 KLF10 TM9SF3

2.00e-04197263e77016d64b1cac9825fec7cfe5071f1567401187
ToppCellsevere-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HMGB1 KMT2C NEB

2.00e-0419726370704b149b2820b8601d2495b7cd9cbe91eda262
ToppCellfacs-Trachea-nan-3m|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK1 KLF10 TM9SF3

2.00e-041972630353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

KMT2C KLF10 PARP14

2.03e-0419826361ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK1 KLF10 TM9SF3

2.03e-04198263f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellCOVID-19-Heart-Mito_CM|Heart / Disease (COVID-19 only), tissue and cell type

ZNF106 NEB MYBPC1

2.03e-04198263b6cd439863d17209b86dc50ae51282dc1725955d
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK1 KLF10 TM9SF3

2.03e-041982632f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF10 RHOU SERPINB2

2.03e-041982637b61f427ed5ca8ad563e5f112fba950a24c9d956
ToppCellfacs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK1 KLF10 TM9SF3

2.03e-0419826322559b161e67b49fe8028bfaf861e069063599f5
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK1 KLF10 TM9SF3

2.06e-041992638d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HMGB1 HMGB2 MYBPC1

2.06e-04199263c7c501ad144ac5488d0b0496554d46616f2e01a6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Mesoderm|3m / Sample Type, Dataset, Time_group, and Cell type.

COBL NEB MYBPC1

2.09e-04200263538ae964db58c4acafe93f735b3e03fc08fdaac6
ToppCellsevere-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KLF10 RHOU SERPINB2

2.09e-04200263db7046741706376682d164c385c4701aebefc2e6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm|6m / Sample Type, Dataset, Time_group, and Cell type.

COBL NEB MYBPC1

2.09e-042002630f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCellsevere-HLA-DR-_S100A+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KLF10 RHOU SERPINB2

2.09e-04200263a5eb50cbf3e94f0b3aa0fbef888989a11cffea37
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Fibcd1_(ventral_GP_(vGP))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CHRNA2 SERPINB2

3.56e-044826263d5d3bbfa9446676d3a53409bc59192abaeabd7
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Fibcd1_(ventral_GP_(vGP))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CHRNA2 SERPINB2

3.56e-044826289449efbb229f36d415ca80e5519308997ec106d
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Fibcd1_(ventral_GP_(vGP))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CHRNA2 SERPINB2

3.56e-04482626cedbfa330eb1c18d7254cb26ddd5f5d3e6d7359
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Ctps_(Ctps)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

BIRC2 NEB

9.39e-04782622b0973122052bb26153f066e7b87c26f8a319698
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

BIRC2 NEB

9.39e-04782621ddbb2247450a8b1c159f524dee15bf688748955
ToppCellDendritic_Cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

NEB SIGLEC8

1.11e-0385262d2776a2c8d1721dbbd7d5dc868a3810e30dd9064
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))|Striatum / BrainAtlas - Mouse McCarroll V32

NEB SERPINB2

1.57e-031012620b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCellCOVID-19-Heart-Fib_+_CM|Heart / Disease (COVID-19 only), tissue and cell type

NEB MYBPC1

1.66e-031042620b60a56a46f1fe3f8224ec6399d009a34a117a21
ToppCellTCGA-Ovary-Primary_Tumor|TCGA-Ovary / Sample_Type by Project: Shred V9

ZNF106 TM9SF3

1.72e-0310626214f548be39cec604fbdae0382cbf434fa4049840
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

ZNF106 TM9SF3

1.72e-03106262939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

ZNF106 TM9SF3

1.72e-03106262e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCellCOVID-19-Heart-Fib_+_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

NEB MYBPC1

1.92e-03112262d00ee6b19e41a35450681fe676885983536d6292
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HMGB1 HMGB2

2.46e-03127262aca98d8c91f2aa0a777b6e9480c9ea70d38ff393
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMGB1 HMGB2

2.50e-031282629ab55a0421cd970e0b8dabce67dd68e382a6bd41
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYBPC1 SERPINB2

2.53e-03129262cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-4|TCGA-Uterus / Sample_Type by Project: Shred V9

NEB MYBPC1

2.61e-031312621801611e6b63aa07629e7ccc692f45a7e93c8dd8
ToppCellEndothelial-H_(cycle)|World / shred on cell class and cell subclass (v4)

HMGB2 SERPINB13

2.69e-031332628e3005114761feee028c496cc739e607b35d7831
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ESS2 RHOU

3.02e-031412627ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCellBLOOD--(3)_MNP-(3)_Classical_Mono-1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HMGB2 SERPINB2

3.06e-03142262395f80e99be4a0ef07fb9d65c74399e7e67c9a8d
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cpa6_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF10 RHOU

3.06e-0314226284742a7e35bab09ee1cca80cfe120b613d6aed6a
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Gkn1_Pcdh19|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF10 RHOU

3.14e-03144262e8caeb6485f4c8f9a3384570dc69024c2bcc9ab0
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NEB MYBPC1

3.14e-03144262f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PARP14 SIGLEC8

3.19e-031452629743d68ba8bfef56fd9a979ab357c0e287eb5ae2
ToppCell356C-Myeloid-Mast_cell-|356C / Donor, Lineage, Cell class and subclass (all cells)

COBL SIGLEC8

3.32e-0314826218511ba10765eda937c5a710626361f7e6b9b321
ToppCellIIH-CD4-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

EMC2 PARP14

3.32e-03148262ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCell356C-Myeloid-Mast_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

COBL SIGLEC8

3.32e-031482621668d8a9e680da335362744f36b05446c499347e
ToppCellE16.5-samps|World / Age Group, Lineage, Cell class and subclass

HMGB1 HMGB2

3.36e-03149262e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-8|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

RHOU SERPINB2

3.36e-031492620c18acfc5f0a9dd25ee5c38f97498b3278e65b42
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NEB MYBPC1

3.36e-03149262797b5f267e86fbe1d7af99df514d8074446603c6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PARP14 SIGLEC8

3.40e-031502626c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCellSevere_COVID-19-undefined|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

TAOK1 SERPINB2

3.45e-031512622ae403417fcb3fe402f6f47bb60ffa68d5fefd2a
ToppCellSevere_COVID-19-undefined-undefined|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

TAOK1 SERPINB2

3.45e-03151262b402185dd7a93c6d0ec5c4d84d5031a157ee8cfb
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EMC2 MYBPC1

3.45e-03151262f13a117ae26ae525da4f3e837d8f204d00dc6ee3
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HMGB1 HMGB2

3.49e-03152262f748ee34167f79ecda116aa1914afab47403385a
ToppCell368C-Myeloid-Mast_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

COBL SIGLEC8

3.49e-03152262faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCell368C-Myeloid-Mast_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

COBL SIGLEC8

3.49e-03152262519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF106 ESS2

3.63e-031552624559e3011514041b65c17ae4ede29da202bce14c
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

SERPINB13 SERPINB2

3.68e-0315626245a05c7a45a3ec8551818ab67f18b3b9553934c1
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMGB2 RHOU

3.72e-031572620673c7161c25feceee8f1e5fd237171576c42c6b
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMGB2 RHOU

3.72e-03157262d307d0b48af35e0e1af41ecd3ebf91be8fd29dc0
ToppCellfacs-Lung-Endomucin-24m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMGB2 CHRNA2

3.77e-03158262b3a810314e253b4fd0f578e759c36fdd21722934
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF10 RHOU

3.77e-031582629e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINB13 SERPINB2

3.77e-03158262e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINB13 SERPINB2

3.77e-0315826212661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMGB2 CHRNA2

3.77e-031582620ed844ab625351a46b74edddf082279ed1bae5c6
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINB13 SERPINB2

3.77e-031582620792c39e6fc0745095af7812de2d50949540d60f
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COBL KLF10

3.86e-03160262d8241404d775f9a709abdf17988f36293fcf4c58
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMGB2 NEB

3.86e-031602625cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMGB2 NEB

3.86e-031602628308ca6f37986c526432a0fbc5f7ec2e75cfb6d7
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COBL CHRNA2

3.91e-031612621e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYBPC1 SERPINB2

3.91e-031612622b94748b0594ae45ead970fa8d4817e65da999e3
ToppCellBL-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SIGLEC8 SERPINB2

3.96e-0316226225ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF10 RHOU

3.96e-031622622d28306c6125b31f11ea6d911a167b93a74907c5
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BIRC2 NEB

4.00e-03163262ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BIRC2 NEB

4.00e-03163262e6213900f56257fe38ac7852351bea0340294be0
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

COBL EMC2

4.00e-03163262be774c0ba38fa89a9c0076524cf05d593c6c6826
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-4|TCGA-Stomach / Sample_Type by Project: Shred V9

SERPINB13 SERPINB2

4.00e-031632626a12b802cb181f979ebc72674f3626fb855024e3
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TAOK2 HMGB2

4.00e-031632623efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BIRC2 NEB

4.00e-03163262ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMGB2 RHOU

4.05e-031642622a230ea066decb798a0e6f2b96c7608c8e608031
ToppCell356C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COBL SIGLEC8

4.05e-03164262f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMGB1 HMGB2

4.05e-0316426272ef807895385ba23e30d19d12b1b0549a699690
ToppCell356C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COBL SIGLEC8

4.05e-03164262b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMGB2 RHOU

4.05e-03164262d02d39edd0bfef5a53b814ec6d5f026d41253218
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

COBL SIGLEC8

4.10e-0316526293d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATG4C HMGB2

4.10e-031652621dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

COBL SIGLEC8

4.10e-031652625fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIRC2 CHRNA2

4.10e-031652628a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellfacs-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG4C ZNF106

4.15e-031662625c132f505dc5f699c87913f140344fc9f8e7e0f5
ComputationalAnti-apoptosis.

BIRC2 SERPINB2

3.55e-0417182MODULE_537
ComputationalNeighborhood of TTN

NEB MYBPC1

8.41e-0426182GNF2_TTN
ComputationalGenes in the cancer module 202.

NEB MYBPC1

9.76e-0428182MODULE_202
ComputationalPhosphatase regulators.

HMGB1 SERPINB2

9.76e-0428182MODULE_281
ComputationalNeighborhood of ANP32B

HMGB1 HMGB2

1.70e-0337182GNF2_ANP32B
ComputationalDNA replication.

HMGB1 HMGB2

2.30e-0343182MODULE_158
ComputationalViral anti-apoptotic evasion mechanisms.

BIRC2 SERPINB2

2.74e-0347182MODULE_312
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HMGB1 HMGB2

2.74e-0347182GAVISH_3CA_METAPROGRAM_B_CELLS_CELL_CYCLE
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HMGB1 HMGB2

2.74e-0347182GAVISH_3CA_METAPROGRAM_MACROPHAGES_CELL_CYCLE
ComputationalGenes in the cancer module 387.

NEB MYBPC1

2.97e-0349182MODULE_387
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

KMT2C NEB

2.97e-0349182GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
ComputationalGenes in the cancer module 201.

NEB MYBPC1

3.09e-0350182MODULE_201
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HMGB1 HMGB2

3.09e-0350182GAVISH_3CA_MALIGNANT_METAPROGRAM_3_CELL_CYLCE_HMG_RICH
ComputationalGenes in the cancer module 329.

NEB MYBPC1

3.22e-0351182MODULE_329
ComputationalNeighborhood of DEK

HMGB1 HMGB2

4.14e-0358182GNF2_DEK
ComputationalGenes in the cancer module 254.

BIRC2 SERPINB2

4.43e-0360182MODULE_254
Diseasecentral nervous system disease (implicated_via_orthology)

TAOK2 TAOK1

8.21e-0516252DOID:331 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

KMT2C MYBPC1

1.56e-0369252DOID:1682 (implicated_via_orthology)
DiseaseHereditary Diffuse Gastric Cancer

BIRC2 KMT2C SERPINB2

1.90e-03293253C1708349
DiseaseStomach Neoplasms

BIRC2 KMT2C SERPINB2

1.97e-03297253C0038356
Diseaseunipolar depression, alcohol dependence

COBL NEB

1.99e-0378252EFO_0003761, MONDO_0007079
DiseaseMalignant neoplasm of stomach

BIRC2 KMT2C SERPINB2

2.03e-03300253C0024623
DiseaseSquamous cell carcinoma of esophagus

HMGB1 KMT2C

2.93e-0395252C0279626
Diseaseautism spectrum disorder (implicated_via_orthology)

TAOK2 TAOK1

7.32e-03152252DOID:0060041 (implicated_via_orthology)
Diseasesquamous cell lung carcinoma

COBL NEB

8.57e-03165252EFO_0000708

Protein segments in the cluster

PeptideGeneStartEntry
NCKMKFGSWTYDKAK

CHRNA2

196

Q15822
KLKTKFISAWNNMKY

ATG4C

11

Q96DT6
CWSYLSTNKKMKSDG

KIAA1107

56

Q9UPP5
YTKNQAWKSMKDTLG

POGLUT1

236

Q8NBL1
HSKSSQYRKMKTEWK

KMT2C

4756

Q8NEZ4
FSKKCSERWKTMSAK

HMGB1

41

P09429
FSKKCSERWKTMSAK

HMGB2

41

P26583
LWNSYQAKKKTMDAK

PARP14

1656

Q460N5
ASVETWKYKAKNSLM

ESS2

211

Q96DF8
SQQDSMKYKDKWATD

COBL

421

O75128
MSMSCSWKSDFKKYV

KLF10

46

Q13118
SAKTKKDNMKYASWA

EMC2

246

Q15006
ITYDKLNKWTSKDKM

SERPINB2

286

P05120
NMTWKIKLKSAMYFS

TAS2R43

161

P59537
MWQKNFKRISYAKTK

MRPL4

101

Q9BYD3
MKWSYKSQLNYKTKQ

SIGLEC8

131

Q9NYZ4
IKKMSYSGKQSTEKW

TAOK1

56

Q7L7X3
IKKMSYSGKQSNEKW

TAOK2

56

Q9UL54
WTNSNKQKMKYDFSC

BIRC2

31

Q13490
DKMKNLSKSWWKKYC

RHOU

241

Q7L0Q8
SGKWAKSKAIMAKYD

UTP14C

301

Q5TAP6
TKEEKFWMNKSTSKS

SERPINB13

196

Q9UIV8
NSGKWAKSKAIMAKY

UTP14A

301

Q9BVJ6
NTKIQMSYSVKWKKS

TM9SF3

186

Q9HD45
MLWNKKSNKSNKYSH

ZNF106

261

Q9H2Y7
YTIQKADKKSMEWFT

MYBPC1

966

Q00872
SQKLYTKGWDESKMK

NEB

3726

P20929