Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR8J3 ABCA1 OR2A7 OXER1 DRD3 HTR2C OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 CYSLTR1 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 GPR101 F2R OR1L3 OR1L1 CHRND OPRK1 OPRL1 OPRM1 GNRHR2 OR1L8 ADORA3 OR4C3 ADRA1A OR10J5 KISS1R OR14A2 OR12D2 P2RY4 CXCR6 LPAR6 OR2A4 OR6J1 MTNR1A C3AR1 OR4K5 OR10J4 OR8D4 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.49e-34	1353	100	52	GO:0004888
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8J3 OR2A7 OXER1 DRD3 HTR2C OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 CYSLTR1 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 GPR101 F2R OR1L3 OR1L1 OPRK1 OPRL1 OPRM1 GNRHR2 OR1L8 ADORA3 OR4C3 ADRA1A OR10J5 KISS1R OR14A2 OR12D2 P2RY4 CXCR6 LPAR6 OR2A4 OR6J1 MTNR1A C3AR1 OR4K5 OR10J4 OR8D4	4.43e-33	884	100	44	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	9.79e-19	431	100	24	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR8J3 OR2A7 OR5AK2 OR5I1 OR9Q2 OR10Q1 OR8H1 OR8K3 OR8J1 OR14A2 OR12D2 OR2A4 OR10J4 OR8D4	2.37e-15	127	100	14	GO:0005549
GeneOntologyMolecularFunction	benzodiazepine receptor activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	6.13e-12	11	100	6	GO:0008503
GeneOntologyMolecularFunction	neurotransmitter receptor activity	DRD3 HTR2C HTR7 CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	7.47e-11	100	100	10	GO:0030594
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.40e-10	18	100	6	GO:0022851
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.49e-10	19	100	6	GO:0004890
GeneOntologyMolecularFunction	GABA receptor activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	9.48e-10	22	100	6	GO:0016917
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	DRD3 CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.81e-09	75	100	8	GO:0098960
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.38e-08	57	100	7	GO:1904315
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.98e-08	60	100	7	GO:0099529
GeneOntologyMolecularFunction	transmitter-gated channel activity	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.51e-08	65	100	7	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.51e-08	65	100	7	GO:0022824
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	ANXA6 CHRND KCNT2 TRPM8 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.59e-08	193	100	10	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	ANXA6 CHRND KCNT2 TRPM8 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.57e-08	197	100	10	GO:0022834
GeneOntologyMolecularFunction	gated channel activity	ANXA6 CHRND OPRM1 KCNT2 KCND1 TRPM8 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.11e-07	334	100	12	GO:0022836
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.15e-07	77	100	7	GO:0005230
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.80e-07	50	100	6	GO:0099095
GeneOntologyMolecularFunction	transporter activity	ABCA1 SPNS2 ANXA6 ATP8B1 SLC30A1 ATP8B2 CHRND OPRM1 SLC5A4 KCNT2 KCND1 ABCD3 TRPM8 SLC30A10 DISP1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.30e-06	1289	100	21	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion channel activity	ANXA6 CHRND OPRM1 KCNT2 KCND1 TRPM8 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.18e-06	459	100	12	GO:0005216
GeneOntologyMolecularFunction	G protein-coupled opioid receptor activity	OPRK1 OPRL1 OPRM1	4.20e-06	7	100	3	GO:0004985
GeneOntologyMolecularFunction	chloride channel activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.61e-06	86	100	6	GO:0005254
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCA1 SPNS2 ANXA6 SLC30A1 CHRND OPRM1 SLC5A4 KCNT2 KCND1 ABCD3 TRPM8 SLC30A10 DISP1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.38e-06	1180	100	19	GO:0022857
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GABRA1 GABRA2 GABRA3 GABRA5	5.83e-06	24	100	4	GO:0099507
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCA1 ATP8B1 ATP8B2	6.70e-06	8	100	3	GO:0090554
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	ANXA6 SLC30A1 CHRND OPRM1 SLC5A4 KCNT2 KCND1 TRPM8 SLC30A10 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	9.22e-06	793	100	15	GO:0015075
GeneOntologyMolecularFunction	channel activity	ANXA6 CHRND OPRM1 KCNT2 KCND1 TRPM8 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.24e-05	525	100	12	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	ANXA6 CHRND OPRM1 KCNT2 KCND1 TRPM8 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.26e-05	526	100	12	GO:0022803
GeneOntologyMolecularFunction	monoatomic anion channel activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.31e-05	103	100	6	GO:0005253
GeneOntologyMolecularFunction	neuropeptide binding	OPRK1 OPRL1 OPRM1 KISS1R	3.44e-05	37	100	4	GO:0042923
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.93e-05	125	100	6	GO:0015108
GeneOntologyMolecularFunction	G protein-coupled amine receptor activity	HTR2C HTR7 TAAR5 ADRA1A	5.20e-05	41	100	4	GO:0008227
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	CYSLTR1 F2R OPRK1 OPRL1 OPRM1 KISS1R	5.57e-05	133	100	6	GO:0008528
GeneOntologyMolecularFunction	floppase activity	ABCA1 ATP8B1 ATP8B2	6.51e-05	16	100	3	GO:0140328
GeneOntologyMolecularFunction	peptide receptor activity	CYSLTR1 F2R OPRK1 OPRL1 OPRM1 KISS1R	7.41e-05	140	100	6	GO:0001653
GeneOntologyMolecularFunction	diazepam binding	GABRA1 GABRA6	7.42e-05	3	100	2	GO:0050809
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC30A1 OPRM1 SLC5A4 KCNT2 KCND1 TRPM8 SLC30A10 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.04e-04	758	100	13	GO:0015318
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.12e-04	151	100	6	GO:0008509
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCA1 ATP8B1 ATP8B2	1.31e-04	20	100	3	GO:0008525
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.21e-04	171	100	6	GO:0015103
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA1 ATP8B1 ATP8B2	3.65e-04	28	100	3	GO:0140326
GeneOntologyMolecularFunction	phosphatidylcholine flippase activity	ATP8B1 ATP8B2	3.68e-04	6	100	2	GO:0140345
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ABCA1 ATP8B1	8.74e-04	9	100	2	GO:0090556
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ABCA1 ATP8B1 ATP8B2	2.13e-03	51	100	3	GO:0140303
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ATP8B1 ATP8B2	2.17e-03	14	100	2	GO:0140333
GeneOntologyMolecularFunction	lipid transporter activity	ABCA1 SPNS2 ATP8B1 ATP8B2 ABCD3	3.07e-03	196	100	5	GO:0005319
GeneOntologyMolecularFunction	flippase activity	ATP8B1 ATP8B2	3.22e-03	17	100	2	GO:0140327
GeneOntologyMolecularFunction	sphingolipid transporter activity	ABCA1 SPNS2	4.45e-03	20	100	2	GO:0046624
GeneOntologyMolecularFunction	peptide binding	OPRK1 OPRL1 OPRM1 GNRHR2 KISS1R LNPEP	5.31e-03	318	100	6	GO:0042277
GeneOntologyMolecularFunction	G protein-coupled serotonin receptor activity	HTR2C HTR7	5.37e-03	22	100	2	GO:0004993
GeneOntologyMolecularFunction	phospholipid transporter activity	ABCA1 ATP8B1 ATP8B2	6.11e-03	74	100	3	GO:0005548
GeneOntologyMolecularFunction	zinc ion transmembrane transporter activity	SLC30A1 SLC30A10	6.38e-03	24	100	2	GO:0005385
GeneOntologyMolecularFunction	G-protein beta-subunit binding	F2R OPRM1	6.91e-03	25	100	2	GO:0031681
GeneOntologyMolecularFunction	outward rectifier potassium channel activity	KCNT2 KCND1	8.03e-03	27	100	2	GO:0015271
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC30A1 OPRM1 SLC5A4 KCNT2 KCND1 TRPM8 SLC30A10	8.87e-03	465	100	7	GO:0046873
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR8J3 ABCA1 OR2A7 OXER1 DRD3 HTR2C OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 CYSLTR1 SPNS2 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 GPR101 F2R OR1L3 OR1L1 OPRK1 OPRL1 OPRM1 GNRHR2 OR1L8 ADORA3 OR4C3 ADRA1A OR10J5 KISS1R OR14A2 OR12D2 P2RY4 CXCR6 LPAR6 OR2A4 OR6J1 MTNR1A C3AR1 OR4K5 OR10J4 OR8D4	5.16e-28	1395	98	46	GO:0007186
GeneOntologyBiologicalProcess	sensory perception of smell	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 SYT10 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	1.05e-19	465	98	25	GO:0007608
GeneOntologyBiologicalProcess	sensory perception	OR8J3 OR2A7 OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 SPNS2 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 ATP8B1 OR8J1 F2R SYT10 OR1L3 OR1L1 OPRK1 OPRL1 OPRM1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 TRPM8 OR4K5 OR10J4 OR8D4	1.33e-19	1072	98	34	GO:0007600
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	2.98e-19	432	98	24	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 SYT10 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	3.70e-19	547	98	26	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	4.27e-18	485	98	24	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR8J3 OR2A7 OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	2.19e-17	582	98	25	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	2.49e-17	524	98	24	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus	OR8J3 OR2A7 OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	3.25e-15	722	98	25	GO:0051606
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	DRD3 HTR2C PSEN2 HTR7 SLC30A1 F2R SYT10 CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 LNPEP GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.34e-10	931	98	22	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	DRD3 HTR2C PSEN2 HTR7 SLC30A1 F2R SYT10 CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 LNPEP GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.34e-10	931	98	22	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	DRD3 HTR2C PSEN2 HTR7 SLC30A1 F2R SYT10 CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 LNPEP GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.92e-10	939	98	22	GO:0099537
GeneOntologyBiologicalProcess	monoatomic ion transport	DRD3 HTR2C PSEN2 HTR7 CYSLTR1 ANXA6 ATP8B1 SLC30A1 F2R ATP8B2 CHRND OPRK1 OPRM1 SLC5A4 ADRA1A KCNT2 P2RY4 KCND1 TRPM8 SLC30A10 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	7.36e-10	1374	98	26	GO:0006811
GeneOntologyBiologicalProcess	phospholipase C-activating G protein-coupled receptor signaling pathway	DRD3 HTR2C F2R OPRK1 OPRL1 OPRM1 ADRA1A P2RY4 LPAR6 C3AR1	7.64e-10	133	98	10	GO:0007200
GeneOntologyBiologicalProcess	synaptic signaling	DRD3 HTR2C PSEN2 HTR7 SLC30A1 F2R SYT10 CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 LNPEP GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	8.09e-10	976	98	22	GO:0099536
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	DRD3 HTR2C PSEN2 ANXA6 ATP8B1 SLC30A1 F2R ATP8B2 CHRND OPRK1 OPRM1 SLC5A4 ADRA1A KCNT2 KCND1 TRPM8 SLC30A10 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.72e-09	1115	98	23	GO:0034220
GeneOntologyBiologicalProcess	inhibitory synapse assembly	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.33e-09	30	98	6	GO:1904862
GeneOntologyBiologicalProcess	gamma-aminobutyric acid signaling pathway	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.43e-08	35	98	6	GO:0007214
GeneOntologyBiologicalProcess	synaptic transmission, GABAergic	ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	6.10e-08	74	98	7	GO:0051932
GeneOntologyBiologicalProcess	chloride transport	ATP8B1 P2RY4 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.74e-07	128	98	8	GO:0006821
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	DRD3 HTR2C PSEN2 SLC30A1 F2R OPRK1 OPRM1 SLC5A4 ADRA1A KCNT2 KCND1 TRPM8 SLC30A10 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.65e-07	1017	98	19	GO:0098660
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	ABCA1 OXER1 DRD3 HTR7 GPR101 OPRK1 OPRL1 OPRM1 ADRA1A MTNR1A	1.07e-06	286	98	10	GO:0007188
GeneOntologyBiologicalProcess	inorganic anion transport	ATP8B1 P2RY4 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.32e-06	180	98	8	GO:0015698
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane potential	CHRND OPRM1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.32e-06	180	98	8	GO:0060078
GeneOntologyBiologicalProcess	monoatomic anion transport	ATP8B1 P2RY4 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-06	183	98	8	GO:0006820
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	OXER1 DRD3 OPRK1 OPRL1 OPRM1 MTNR1A	3.41e-06	86	98	6	GO:0007193
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	HTR2C HTR7 OPRM1 OR10J5 MTNR1A	1.05e-05	61	98	5	GO:0007187
GeneOntologyBiologicalProcess	signal release	ABCA1 DRD3 HTR2C HTR7 SLC30A1 F2R SYT10 OPRK1 OPRM1 ADORA3 KISS1R P2RY4 MTNR1A	1.29e-05	653	98	13	GO:0023061
GeneOntologyBiologicalProcess	chloride transmembrane transport	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.57e-05	112	98	6	GO:1902476
GeneOntologyBiologicalProcess	G protein-coupled opioid receptor signaling pathway	OPRK1 OPRL1 OPRM1	2.87e-05	13	98	3	GO:0038003
GeneOntologyBiologicalProcess	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ABCA1 DRD3 HTR7 GPR101 OPRL1 OPRM1 ADRA1A	3.56e-05	191	98	7	GO:0007189
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.33e-05	134	98	6	GO:0098661
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting opioid receptor signaling pathway	OPRK1 OPRM1	6.68e-05	3	98	2	GO:0031635
GeneOntologyBiologicalProcess	detoxification of zinc ion	SLC30A1 SLC30A10	6.68e-05	3	98	2	GO:0010312
GeneOntologyBiologicalProcess	stress response to zinc ion	SLC30A1 SLC30A10	6.68e-05	3	98	2	GO:1990359
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	DRD3 HTR2C PSEN2 HTR7 SLC30A1 F2R OPRM1 ADORA3 ADRA1A KISS1R P2RY4 LNPEP	7.17e-05	663	98	12	GO:0050804
GeneOntologyBiologicalProcess	metal ion transport	DRD3 HTR2C PSEN2 CYSLTR1 ANXA6 SLC30A1 F2R OPRK1 OPRM1 SLC5A4 ADRA1A KCNT2 KCND1 TRPM8 SLC30A10	7.27e-05	1000	98	15	GO:0030001
GeneOntologyBiologicalProcess	regulation of trans-synaptic signaling	DRD3 HTR2C PSEN2 HTR7 SLC30A1 F2R OPRM1 ADORA3 ADRA1A KISS1R P2RY4 LNPEP	7.27e-05	664	98	12	GO:0099177
GeneOntologyBiologicalProcess	negative regulation of secretion by cell	DRD3 HTR7 SLC30A1 F2R OPRK1 OPRM1 MTNR1A	7.30e-05	214	98	7	GO:1903531
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	9.06e-05	153	98	6	GO:0098656
GeneOntologyBiologicalProcess	positive regulation of cytosolic calcium ion concentration	CYSLTR1 F2R OPRM1 ADRA1A P2RY4 CXCR6 C3AR1	9.71e-05	224	98	7	GO:0007204
GeneOntologyBiologicalProcess	regulation of vasoconstriction	HTR2C HTR7 CYSLTR1 F2R ADRA1A	1.05e-04	98	98	5	GO:0019229
GeneOntologyBiologicalProcess	monoatomic cation transport	DRD3 HTR2C PSEN2 CYSLTR1 ANXA6 SLC30A1 F2R CHRND OPRK1 OPRM1 SLC5A4 ADRA1A KCNT2 KCND1 TRPM8 SLC30A10	1.06e-04	1157	98	16	GO:0006812
GeneOntologyBiologicalProcess	positive regulation of vasoconstriction	HTR2C CYSLTR1 F2R ADRA1A	1.26e-04	54	98	4	GO:0045907
GeneOntologyBiologicalProcess	sensory perception of pain	HTR7 F2R OPRK1 OPRL1 OPRM1	1.45e-04	105	98	5	GO:0019233
GeneOntologyBiologicalProcess	negative regulation of secretion	DRD3 HTR7 SLC30A1 F2R OPRK1 OPRM1 MTNR1A	1.45e-04	239	98	7	GO:0051048
GeneOntologyBiologicalProcess	calcium ion transport	DRD3 HTR2C PSEN2 CYSLTR1 ANXA6 SLC30A1 F2R OPRM1 ADRA1A TRPM8	1.54e-04	509	98	10	GO:0006816
GeneOntologyBiologicalProcess	regulation of secretion by cell	DRD3 HTR2C HTR7 SLC30A1 F2R SYT10 OPRK1 OPRM1 ADORA3 KISS1R P2RY4 MTNR1A	2.00e-04	740	98	12	GO:1903530
GeneOntologyBiologicalProcess	adenylate cyclase-activating adrenergic receptor signaling pathway	DRD3 GPR101 ADRA1A	2.22e-04	25	98	3	GO:0071880
GeneOntologyBiologicalProcess	monoamine transport	DRD3 HTR7 OPRK1 ADORA3 MAPK15	2.31e-04	116	98	5	GO:0015844
GeneOntologyBiologicalProcess	cellular response to dopamine	DRD3 HTR2C HTR7 OPRM1	2.45e-04	64	98	4	GO:1903351
GeneOntologyBiologicalProcess	blood circulation	DRD3 HTR2C PSEN2 HTR7 CYSLTR1 F2R OPRL1 ADORA3 ADRA1A LNPEP C3AR1	2.54e-04	648	98	11	GO:0008015
GeneOntologyBiologicalProcess	response to dopamine	DRD3 HTR2C HTR7 OPRM1	2.76e-04	66	98	4	GO:1903350
GeneOntologyBiologicalProcess	calcium-mediated signaling	HTR2C OPRL1 ADORA3 KISS1R CXCR6 TRPM8 C3AR1	2.79e-04	266	98	7	GO:0019722
GeneOntologyBiologicalProcess	vasoconstriction	HTR2C HTR7 CYSLTR1 F2R ADRA1A	2.81e-04	121	98	5	GO:0042310
GeneOntologyBiologicalProcess	presynaptic modulation of chemical synaptic transmission	HTR7 OPRM1 ADORA3 ADRA1A	2.92e-04	67	98	4	GO:0099171
GeneOntologyBiologicalProcess	organic hydroxy compound transport	ABCA1 DRD3 HTR7 ATP8B1 OPRK1 ADORA3 MAPK15 ABCD3	3.08e-04	358	98	8	GO:0015850
GeneOntologyBiologicalProcess	cellular response to monoamine stimulus	DRD3 HTR2C HTR7 OPRM1	3.09e-04	68	98	4	GO:0071868
GeneOntologyBiologicalProcess	cellular response to catecholamine stimulus	DRD3 HTR2C HTR7 OPRM1	3.09e-04	68	98	4	GO:0071870
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	DRD3 HTR2C PSEN2 ANXA6 SLC30A1 F2R P2RY4 TRPM8	3.14e-04	359	98	8	GO:0006874
GeneOntologyBiologicalProcess	neuropeptide signaling pathway	CYSLTR1 OPRK1 OPRL1 OPRM1 KISS1R	3.15e-04	124	98	5	GO:0007218
GeneOntologyBiologicalProcess	regulation of membrane potential	CHRND OPRM1 ADRA1A KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.26e-04	559	98	10	GO:0042391
GeneOntologyBiologicalProcess	negative regulation of luteinizing hormone secretion	OPRK1 OPRM1	3.31e-04	6	98	2	GO:0033685
GeneOntologyBiologicalProcess	conditioned place preference	OPRK1 OPRL1	3.31e-04	6	98	2	GO:1990708
GeneOntologyBiologicalProcess	export from cell	ABCA1 DRD3 HTR2C HTR7 SLC30A1 F2R SYT10 OPRK1 OPRM1 ADORA3 KISS1R KCNT2 P2RY4 MTNR1A SLC30A10	3.44e-04	1153	98	15	GO:0140352
GeneOntologyBiologicalProcess	positive regulation of MAPK cascade	DRD3 HTR2C RB1CC1 GPR101 F2R OPRK1 OPRM1 ADRA1A KISS1R SLC30A10	3.85e-04	571	98	10	GO:0043410
GeneOntologyBiologicalProcess	response to catecholamine	DRD3 HTR2C HTR7 OPRM1	4.06e-04	73	98	4	GO:0071869
GeneOntologyBiologicalProcess	regulation of secretion	DRD3 HTR2C HTR7 SLC30A1 F2R SYT10 OPRK1 OPRM1 ADORA3 KISS1R P2RY4 MTNR1A	4.11e-04	801	98	12	GO:0051046
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	DRD3 HTR2C PSEN2 SLC30A1 F2R OPRK1 OPRM1 SLC5A4 ADRA1A KCNT2 KCND1 TRPM8 SLC30A10	4.16e-04	922	98	13	GO:0098662
GeneOntologyBiologicalProcess	reproductive behavior	TAAR5 OPRK1 OPRM1 MTNR1A	4.27e-04	74	98	4	GO:0019098
GeneOntologyBiologicalProcess	response to monoamine	DRD3 HTR2C HTR7 OPRM1	4.27e-04	74	98	4	GO:0071867
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	DRD3 HTR2C PSEN2 SLC30A1 F2R OPRK1 OPRM1 SLC5A4 ADRA1A KCNT2 KCND1 TRPM8 SLC30A10	5.10e-04	942	98	13	GO:0098655
GeneOntologyBiologicalProcess	calcium ion homeostasis	DRD3 HTR2C PSEN2 ANXA6 SLC30A1 F2R P2RY4 TRPM8	5.35e-04	389	98	8	GO:0055074
GeneOntologyBiologicalProcess	adrenergic receptor signaling pathway	DRD3 GPR101 ADRA1A	6.10e-04	35	98	3	GO:0071875
GeneOntologyBiologicalProcess	circulatory system process	DRD3 HTR2C PSEN2 HTR7 CYSLTR1 F2R OPRL1 ADORA3 ADRA1A LNPEP C3AR1	7.15e-04	733	98	11	GO:0003013
GeneOntologyBiologicalProcess	export across plasma membrane	ABCA1 SLC30A1 KCNT2 SLC30A10	9.33e-04	91	98	4	GO:0140115
GeneOntologyBiologicalProcess	regulation of blood pressure	DRD3 F2R OPRL1 ADRA1A LNPEP C3AR1	9.43e-04	237	98	6	GO:0008217
GeneOntologyBiologicalProcess	regulation of luteinizing hormone secretion	OPRK1 OPRM1	9.81e-04	10	98	2	GO:0033684
GeneOntologyBiologicalProcess	catecholamine transport	DRD3 OPRK1 ADORA3 MAPK15	1.14e-03	96	98	4	GO:0051937
GeneOntologyBiologicalProcess	serotonin receptor signaling pathway	HTR2C HTR7	1.20e-03	11	98	2	GO:0007210
GeneOntologyBiologicalProcess	zinc ion import into organelle	SLC30A1 SLC30A10	1.20e-03	11	98	2	GO:0062111
GeneOntologyBiologicalProcess	negative regulation of gonadotropin secretion	OPRK1 OPRM1	1.20e-03	11	98	2	GO:0032277
GeneOntologyBiologicalProcess	regulation of Rho protein signal transduction	ABCA1 F2R ADRA1A LPAR6	1.23e-03	98	98	4	GO:0035023
GeneOntologyBiologicalProcess	response to histamine	DRD3 GABRA1	1.43e-03	12	98	2	GO:0034776
GeneOntologyBiologicalProcess	negative regulation of protein secretion	DRD3 F2R OPRM1 MTNR1A	1.48e-03	103	98	4	GO:0050709
GeneOntologyBiologicalProcess	secretion by cell	ABCA1 DRD3 HTR2C HTR7 SLC30A1 F2R SYT10 OPRK1 OPRM1 ADORA3 KISS1R P2RY4 MTNR1A	1.56e-03	1064	98	13	GO:0032940
GeneOntologyBiologicalProcess	adenylate cyclase-activating dopamine receptor signaling pathway	DRD3 OPRM1	1.68e-03	13	98	2	GO:0007191
GeneOntologyBiologicalProcess	luteinizing hormone secretion	OPRK1 OPRM1	1.96e-03	14	98	2	GO:0032275
GeneOntologyBiologicalProcess	negative regulation of cAMP-mediated signaling	OPRL1 OPRM1	1.96e-03	14	98	2	GO:0043951
GeneOntologyBiologicalProcess	learning or memory	DRD3 HTR2C PSEN2 HTR7 OPRK1 OPRL1 GABRA5	2.02e-03	373	98	7	GO:0007611
GeneOntologyBiologicalProcess	response to morphine	DRD3 OPRM1	2.25e-03	15	98	2	GO:0043278
GeneOntologyBiologicalProcess	phospholipid translocation	ABCA1 ATP8B1 ATP8B2	2.28e-03	55	98	3	GO:0045332
GeneOntologyCellularComponent	synaptic membrane	DRD3 PSEN2 HTR7 SLC30A1 F2R CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A P2RY4 KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.52e-11	583	100	19	GO:0097060
GeneOntologyCellularComponent	GABA-A receptor complex	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.66e-10	19	100	6	GO:1902711
GeneOntologyCellularComponent	GABA receptor complex	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.27e-10	21	100	6	GO:1902710
GeneOntologyCellularComponent	postsynaptic membrane	DRD3 HTR7 SLC30A1 F2R CHRND OPRK1 OPRM1 ADRA1A KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	8.90e-10	405	100	15	GO:0045211
GeneOntologyCellularComponent	dendrite membrane	OPRM1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	8.87e-09	56	100	7	GO:0032590
GeneOntologyCellularComponent	presynaptic membrane	PSEN2 HTR7 OPRK1 OPRM1 ADORA3 ADRA1A P2RY4 GABRA2 GABRA3 GABRA5 GABRA6	9.05e-08	277	100	11	GO:0042734
GeneOntologyCellularComponent	GABA-ergic synapse	DRD3 OPRM1 ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	9.33e-08	164	100	9	GO:0098982
GeneOntologyCellularComponent	neuron projection membrane	OPRM1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.31e-07	82	100	7	GO:0032589
GeneOntologyCellularComponent	chloride channel complex	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.07e-07	57	100	6	GO:0034707
GeneOntologyCellularComponent	postsynaptic specialization membrane	DRD3 SLC30A1 CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.25e-07	201	100	9	GO:0099634
GeneOntologyCellularComponent	leading edge membrane	OPRM1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	6.79e-05	210	100	7	GO:0031256
GeneOntologyCellularComponent	presynapse	PSEN2 HTR7 RABAC1 SYT10 OPRK1 OPRM1 ADORA3 ADRA1A P2RY4 SLC30A10 GABRA2 GABRA3 GABRA5 GABRA6	8.12e-05	886	100	14	GO:0098793
GeneOntologyCellularComponent	postsynapse	DRD3 HTR7 SLC30A1 F2R CHRND OPRK1 OPRM1 ADRA1A KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	9.68e-05	1018	100	15	GO:0098794
GeneOntologyCellularComponent	dendrite	HTR2C HTR7 SLC30A1 OPRK1 OPRM1 ADORA3 KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.25e-04	858	100	13	GO:0030425
GeneOntologyCellularComponent	somatodendritic compartment	HTR2C PSEN2 HTR7 SLC30A1 OPRK1 OPRM1 ADORA3 KCND1 LNPEP MTNR1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.29e-04	1228	100	16	GO:0036477
GeneOntologyCellularComponent	dendritic tree	HTR2C HTR7 SLC30A1 OPRK1 OPRM1 ADORA3 KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.30e-04	860	100	13	GO:0097447
GeneOntologyCellularComponent	transporter complex	ATP8B1 ATP8B2 CHRND KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.04e-04	550	100	10	GO:1990351
GeneOntologyCellularComponent	monoatomic ion channel complex	CHRND KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.65e-04	378	100	8	GO:0034702
GeneOntologyCellularComponent	receptor complex	HTR2C GPR101 CHRND MTNR1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.68e-04	581	100	10	GO:0043235
GeneOntologyCellularComponent	T-tubule	SLC30A1 OPRK1 OPRM1 ADRA1A	5.63e-04	79	100	4	GO:0030315
GeneOntologyCellularComponent	postsynaptic specialization	DRD3 SLC30A1 CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	6.90e-04	503	100	9	GO:0099572
GeneOntologyCellularComponent	exocytic vesicle	PSEN2 HTR7 RABAC1 SYT10 OPRK1 SLC30A10 GABRA2	8.75e-04	320	100	7	GO:0070382
GeneOntologyCellularComponent	cell projection membrane	ATP8B1 OPRM1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.09e-03	431	100	8	GO:0031253
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	MON2 SPNS2 ANXA6 SLC30A1 SYT10 OPRK1 CD1B LNPEP NBEAL2 CD58 C3AR1 PCDH7 SLC30A10 GABRA1 GABRA2	1.35e-03	1307	100	15	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	MON2 SPNS2 ANXA6 SLC30A1 SYT10 OPRK1 CD1B LNPEP NBEAL2 CD58 C3AR1 PCDH7 SLC30A10 GABRA1 GABRA2	1.55e-03	1325	100	15	GO:0012506
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP8B1 ATP8B2	1.99e-03	14	100	2	GO:1990531
GeneOntologyCellularComponent	sarcolemma	ANXA6 SLC30A1 OPRK1 OPRM1 ADRA1A	2.21e-03	190	100	5	GO:0042383
GeneOntologyCellularComponent	mitotic spindle midzone	OR2A7 OR2A4	2.60e-03	16	100	2	GO:1990023
GeneOntologyCellularComponent	synaptic vesicle	PSEN2 HTR7 RABAC1 OPRK1 SLC30A10 GABRA2	3.21e-03	300	100	6	GO:0008021
GeneOntologyCellularComponent	transmembrane transporter complex	CHRND KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.62e-03	523	100	8	GO:1902495
GeneOntologyCellularComponent	dopaminergic synapse	DRD3 ADRA1A	4.92e-03	22	100	2	GO:0098691
GeneOntologyCellularComponent	presynaptic active zone membrane	P2RY4 GABRA2 GABRA3	6.23e-03	78	100	3	GO:0048787
GeneOntologyCellularComponent	secretory vesicle	PSEN2 HTR7 RABAC1 SYT10 OPRK1 FRK LNPEP NBEAL2 CD58 C3AR1 PCDH7 SLC30A10 GABRA2	6.39e-03	1246	100	13	GO:0099503
GeneOntologyCellularComponent	neuronal cell body	PSEN2 HTR7 OPRK1 OPRM1 KCND1 LNPEP MTNR1A GABRA2 GABRA5 GABRA6	6.64e-03	835	100	10	GO:0043025
GeneOntologyCellularComponent	nuclear membrane	PSEN2 DHX37 RB1CC1 SLC30A1 ADRA1A NUP210	6.65e-03	349	100	6	GO:0031965
MousePheno	impaired behavioral response to xenobiotic	DRD3 HTR2C OPRK1 OPRL1 OPRM1 GABRA1 GABRA2 GABRA4	2.50e-09	83	61	8	MP:0009747
MousePheno	abnormal GABA-mediated receptor currents	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5	1.10e-08	18	61	5	MP:0004008
MousePheno	impaired behavioral response to morphine	DRD3 OPRK1 OPRL1 OPRM1	6.76e-08	10	61	4	MP:0009757
MousePheno	abnormal behavioral response to morphine	DRD3 OPRK1 OPRL1 OPRM1	2.28e-07	13	61	4	MP:0020159
MousePheno	abnormal behavioral response to xenobiotic	DRD3 HTR2C HTR7 OPRK1 OPRL1 OPRM1 GABRA1 GABRA2 GABRA4 GABRA5	8.01e-07	309	61	10	MP:0009745
MousePheno	abnormal behavioral response to anesthetic	OPRK1 OPRM1 GABRA2	1.69e-05	12	61	3	MP:0009777
MousePheno	abnormal touch/ nociception	ABCA1 HIVEP2 HTR7 OPRK1 OPRL1 OPRM1 ADORA3 TRPM8 GABRA4	3.37e-05	376	61	9	MP:0001968
MousePheno	abnormal sensory capabilities/reflexes/nociception	ABCA1 DRD3 HIVEP2 HTR2C HTR7 SPNS2 ATP8B1 OPRK1 OPRL1 OPRM1 ADORA3 MAPK15 ABCD3 TRPM8 GABRA1 GABRA2 GABRA3 GABRA4	4.06e-05	1486	61	18	MP:0002067
MousePheno	impaired behavioral response to addictive substance	DRD3 OPRK1 OPRL1 OPRM1	4.28e-05	45	61	4	MP:0009750
MousePheno	abnormal associative learning	DRD3 HTR2C OPRK1 OPRL1 OPRM1 KCNT2 GABRA1 GABRA2 GABRA5	4.76e-05	393	61	9	MP:0002062
MousePheno	decreased chemically-elicited antinociception	OPRK1 OPRL1 OPRM1	7.29e-05	19	61	3	MP:0001982
MousePheno	abnormal thermal nociception	HIVEP2 HTR7 OPRL1 OPRM1 TRPM8 GABRA4	8.86e-05	168	61	6	MP:0002733
MousePheno	abnormal pain threshold	HIVEP2 HTR7 OPRK1 OPRL1 OPRM1 TRPM8 GABRA4	1.55e-04	267	61	7	MP:0001970
MousePheno	impaired behavioral response to anesthetic	OPRK1 OPRM1	1.86e-04	5	61	2	MP:0009778
MousePheno	enhanced behavioral response to anesthetic	OPRM1 GABRA2	1.86e-04	5	61	2	MP:0009779
MousePheno	enhanced behavioral response to xenobiotic	DRD3 HTR2C OPRM1 GABRA2	2.29e-04	69	61	4	MP:0009746
MousePheno	abnormal chemically-elicited antinociception	OPRK1 OPRL1 OPRM1	2.66e-04	29	61	3	MP:0001980
MousePheno	enhanced conditioning behavior	OPRM1 KCNT2 GABRA2 GABRA5	2.70e-04	72	61	4	MP:0012316
MousePheno	increased coping response	HTR2C OPRM1 ARHGEF10	5.09e-04	36	61	3	MP:0003063
Domain	7tm_1	OR8J3 OR2A7 OXER1 DRD3 HTR2C OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 CYSLTR1 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 GPR101 F2R OR1L3 OR1L1 OPRK1 OPRL1 OPRM1 GNRHR2 OR1L8 ADORA3 OR4C3 ADRA1A OR10J5 KISS1R OR12D2 P2RY4 CXCR6 LPAR6 OR2A4 OR6J1 MTNR1A C3AR1 OR4K5 OR8D4	4.33e-35	677	96	42	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR8J3 OR2A7 OXER1 DRD3 HTR2C OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 CYSLTR1 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 GPR101 F2R OR1L3 OR1L1 OPRK1 OPRL1 OPRM1 GNRHR2 OR1L8 ADORA3 OR4C3 ADRA1A OR10J5 KISS1R OR12D2 P2RY4 CXCR6 LPAR6 OR2A4 OR6J1 MTNR1A C3AR1 OR4K5 OR8D4	7.04e-35	685	96	42	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR8J3 OR2A7 OXER1 DRD3 HTR2C OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 CYSLTR1 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 GPR101 F2R OR1L3 OR1L1 OPRK1 OPRL1 OPRM1 GNRHR2 OR1L8 ADORA3 OR4C3 ADRA1A OR10J5 KISS1R OR12D2 P2RY4 CXCR6 LPAR6 OR2A4 OR6J1 MTNR1A C3AR1 OR4K5 OR8D4	1.01e-34	691	96	42	PS50262
Domain	GPCR_Rhodpsn	OR8J3 OR2A7 OXER1 DRD3 HTR2C OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 CYSLTR1 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 GPR101 F2R OR1L3 OR1L1 OPRK1 OPRL1 OPRM1 GNRHR2 OR1L8 ADORA3 OR4C3 ADRA1A OR10J5 KISS1R OR12D2 P2RY4 CXCR6 LPAR6 OR2A4 OR6J1 MTNR1A C3AR1 OR4K5 OR8D4	1.07e-34	692	96	42	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR8J3 OR2A7 OXER1 DRD3 HTR2C OR5AK2 OR5V1 HTR7 OR2T35 OR5I1 CYSLTR1 OR9Q2 OR10Q1 TAAR5 OR8H1 OR2T2 OR8K3 OR8J1 GPR101 F2R OR1L3 OR1L1 OPRK1 OPRL1 OPRM1 OR1L8 ADORA3 OR4C3 ADRA1A OR10J5 KISS1R OR12D2 P2RY4 CXCR6 LPAR6 OR2A4 MTNR1A C3AR1 OR4K5 OR8D4	1.29e-32	670	96	40	IPR017452
Domain	Olfact_rcpt	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR12D2 OR2A4 OR6J1 OR4K5 OR8D4	4.59e-17	393	96	22	IPR000725
Domain	GABAAa_rcpt	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.57e-14	6	96	6	IPR001390
Domain	GABAA/Glycine_rcpt	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.48e-09	23	96	6	IPR006028
Domain	Neurotransmitter_ion_chnl_CS	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.94e-09	45	96	7	IPR018000
Domain	Neur_chan_memb	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.45e-09	46	96	7	PF02932
Domain	Neur_chan_LBD	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.04e-09	47	96	7	PF02931
Domain	NEUROTR_ION_CHANNEL	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.04e-09	47	96	7	PS00236
Domain	Neurotrans-gated_channel_TM	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.04e-09	47	96	7	IPR006029
Domain	-	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.04e-09	47	96	7	2.70.170.10
Domain	Neur_channel	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.04e-09	47	96	7	IPR006201
Domain	Neur_chan_lig-bd	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.04e-09	47	96	7	IPR006202
Domain	7TM_GPCR_Srsx	DRD3 HTR2C TAAR5 OR1L3 OPRK1 OPRL1 ADORA3 ADRA1A MTNR1A	6.07e-09	112	96	9	SM01381
Domain	Opioid_rcpt	OPRK1 OPRL1 OPRM1	5.24e-07	4	96	3	IPR001418
Domain	Cation_efflux	SLC30A1 SLC30A10	1.15e-03	10	96	2	IPR002524
Domain	Cation_efflux	SLC30A1 SLC30A10	1.15e-03	10	96	2	PF01545
Domain	-	SLC30A1 SLC30A10	1.40e-03	11	96	2	1.20.1510.10
Domain	Cation_efflux_TMD	SLC30A1 SLC30A10	1.40e-03	11	96	2	IPR027469
Domain	P_typ_ATPase_c	ATP8B1 ATP8B2	2.29e-03	14	96	2	IPR032630
Domain	P-type_ATPase_N	ATP8B1 ATP8B2	2.29e-03	14	96	2	IPR032631
Domain	P-type_ATPase_IV	ATP8B1 ATP8B2	2.29e-03	14	96	2	IPR006539
Domain	PhoLip_ATPase_C	ATP8B1 ATP8B2	2.29e-03	14	96	2	PF16212
Domain	PhoLip_ATPase_N	ATP8B1 ATP8B2	2.29e-03	14	96	2	PF16209
Domain	-	ATP8B1 ATP8B2	1.17e-02	32	96	2	3.40.1110.10
Domain	-	ATP8B1 ATP8B2	1.17e-02	32	96	2	2.70.150.10
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	DRD3 HTR2C HTR7 CYSLTR1 TAAR5 F2R CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 LPAR6 MTNR1A C3AR1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.11e-19	272	94	23	M13380
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	2.28e-16	417	94	24	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR8J3 OR2A7 OR5AK2 OR5V1 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR12D2 OR2A4 OR4K5 OR8D4	8.41e-13	389	94	20	M14091
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	DRD3 HTR2C OR5V1 HTR7 OR5I1 CYSLTR1 F2R OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A P2RY4 LPAR6 OR2A4 MTNR1A C3AR1	1.16e-12	260	94	17	M39397
Pathway	REACTOME_SENSORY_PERCEPTION	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR6J1 OR4K5 OR10J4 OR8D4	2.46e-12	636	94	24	M41834
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	OXER1 DRD3 HTR2C HTR7 CYSLTR1 TAAR5 F2R OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 CXCR6 LPAR6 MTNR1A C3AR1	5.04e-12	330	94	18	M18334
Pathway	BIOCARTA_FLUMAZENIL_PATHWAY	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	6.18e-12	9	94	6	M22034
Pathway	BIOCARTA_GABA_PATHWAY	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.54e-11	10	94	6	M477
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	DRD3 HTR2C HTR7 CYSLTR1 F2R OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A OR10J5 P2RY4 MTNR1A C3AR1	2.06e-11	186	94	14	MM15994
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	DRD3 HTR2C HTR7 CYSLTR1 TAAR5 F2R OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 CXCR6 LPAR6 MTNR1A C3AR1	5.99e-11	333	94	17	MM14963
Pathway	WP_GPCRS_NONODORANT	DRD3 HTR2C HTR7 CYSLTR1 F2R OPRK1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 CXCR6 LPAR6 MTNR1A C3AR1	2.27e-10	266	94	15	MM15843
Pathway	REACTOME_GPCR_LIGAND_BINDING	OXER1 DRD3 HTR2C HTR7 CYSLTR1 TAAR5 F2R OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 CXCR6 LPAR6 MTNR1A C3AR1	1.28e-09	463	94	18	M507
Pathway	BIOCARTA_GABA_PATHWAY	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5	2.91e-09	10	94	5	MM1401
Pathway	REACTOME_GPCR_LIGAND_BINDING	DRD3 HTR2C HTR7 CYSLTR1 TAAR5 F2R OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 CXCR6 LPAR6 MTNR1A C3AR1	3.05e-09	430	94	17	MM15160
Pathway	WP_GABA_RECEPTOR_SIGNALING	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.81e-08	31	94	6	M39369
Pathway	REACTOME_SIGNALING_BY_GPCR	OXER1 DRD3 HTR2C HTR7 CYSLTR1 TAAR5 F2R OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 CXCR6 ARHGEF10 LPAR6 MTNR1A C3AR1	1.48e-07	702	94	19	M746
Pathway	WP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.74e-07	38	94	6	M39854
Pathway	REACTOME_SIGNALING_BY_GPCR	DRD3 HTR2C HTR7 CYSLTR1 TAAR5 F2R OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A KISS1R P2RY4 CXCR6 ARHGEF10 LPAR6 MTNR1A C3AR1	2.16e-07	646	94	18	MM14962
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.80e-06	60	94	6	M976
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.80e-06	60	94	6	MM15708
Pathway	WP_GPCRS_OTHER	OR2A7 CYSLTR1 OPRK1 OPRL1 OPRM1 ADORA3 OR2A4	3.44e-06	96	94	7	MM15939
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	DRD3 HTR2C HTR7 TAAR5 ADRA1A	8.29e-06	42	94	5	M5868
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	DRD3 HTR2C HTR7 TAAR5 ADRA1A	8.29e-06	42	94	5	MM14971
Pathway	WP_EFFECT_OF_OMEGA3_PUFA_ON_HUNTINGTONS_DISEASE_PATHWAYS	ABCA1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.43e-05	119	94	7	M48309
Pathway	WP_GPCRS_OTHER	DRD3 HTR7 TAAR5 F2R ADORA3 OR2A4	3.58e-05	93	94	6	M39629
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	OXER1 DRD3 OPRK1 OPRL1 OPRM1 ADORA3 P2RY4 CXCR6 MTNR1A C3AR1	4.50e-05	314	94	10	M600
Pathway	WP_NUCLEOTIDE_GPCRS	ADORA3 P2RY4 LPAR6	4.56e-05	11	94	3	M39422
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.89e-05	144	94	7	MM14501
Pathway	WP_MONOAMINE_GPCRS	DRD3 HTR2C HTR7 ADRA1A	5.08e-05	31	94	4	MM15871
Pathway	WP_NUCLEOTIDE_GPCRS	ADORA3 P2RY4 LPAR6	6.05e-05	12	94	3	MM15953
Pathway	WP_MONOAMINE_GPCRS	DRD3 HTR2C HTR7 ADRA1A	6.54e-05	33	94	4	M39585
Pathway	WP_GPCRS_PEPTIDE	OPRK1 OPRL1 OPRM1 CXCR6 C3AR1	1.02e-04	70	94	5	MM15959
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	DRD3 OPRK1 OPRL1 OPRM1 ADORA3 P2RY4 CXCR6 MTNR1A C3AR1	1.31e-04	289	94	9	MM15057
Pathway	WP_PEPTIDE_GPCRS	OPRK1 OPRL1 OPRM1 CXCR6 C3AR1	1.41e-04	75	94	5	M39696
Pathway	REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS	ADORA3 P2RY4 LPAR6	1.51e-04	16	94	3	M6786
Pathway	REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS	ADORA3 P2RY4 LPAR6	1.51e-04	16	94	3	MM15050
Pathway	WP_SEROTONIN_AND_ANXIETY	HTR2C ADRA1A GABRA1	1.82e-04	17	94	3	M39511
Pathway	WP_SEROTONIN_AND_ANXIETY	HTR2C ADRA1A GABRA1	1.82e-04	17	94	3	MM15861
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY	HTR2C CYSLTR1 F2R ADRA1A	3.38e-04	50	94	4	M47951
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	F2R OPRK1 OPRL1 OPRM1 KISS1R CXCR6 C3AR1	3.43e-04	197	94	7	M12289
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	F2R OPRK1 OPRL1 OPRM1 KISS1R CXCR6 C3AR1	3.43e-04	197	94	7	MM14970
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.36e-04	205	94	7	M752
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.18e-04	211	94	7	MM14502
Pathway	WP_ADHD_AND_AUTISM_ASD_PATHWAYS	HTR7 RB1CC1 OPRM1 ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5	7.55e-04	367	94	9	M48346
Pathway	WP_PURINERGIC_SIGNALING	ADORA3 P2RY4 LPAR6	1.36e-03	33	94	3	M39855
Pathway	REACTOME_NEURONAL_SYSTEM	SYT10 CHRND KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.66e-03	411	94	9	M735
Pathway	REACTOME_NEURONAL_SYSTEM	CHRND KCND1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.77e-03	335	94	8	MM14503
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	CHRND GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.17e-03	270	94	7	M15514
Pathway	REACTOME_P2Y_RECEPTORS	P2RY4 LPAR6	2.33e-03	11	94	2	MM15049
Pathway	REACTOME_SEROTONIN_RECEPTORS	HTR2C HTR7	2.33e-03	11	94	2	MM15008
Pathway	REACTOME_P2Y_RECEPTORS	P2RY4 LPAR6	2.78e-03	12	94	2	M10960
Pathway	REACTOME_SEROTONIN_RECEPTORS	HTR2C HTR7	2.78e-03	12	94	2	M6034
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	HTR2C CYSLTR1 F2R ADRA1A KISS1R LPAR6	2.79e-03	210	94	6	MM15043
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	HTR2C CYSLTR1 F2R ADRA1A KISS1R LPAR6	3.28e-03	217	94	6	M18437
Pathway	WP_GPCRS_ODORANT	OR2A7 TAAR5 GPR101 OPRL1 OR2A4	3.98e-03	157	94	5	MM15872
Pathway	REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS	OXER1 CYSLTR1	4.37e-03	15	94	2	M10620
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR8K3 OR8J1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR4K5 OR8D4	3.10e-19	340	101	19	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR8K3 OR8J1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR4K5 OR8D4	3.10e-19	340	101	19	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR8K3 OR8J1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR4K5 OR8D4	3.65e-19	343	101	19	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR9Q2 OR10Q1 OR8H1 OR8K3 OR8J1 OR1L8 OR4C3 OR10J5 OR14A2 OR12D2 OR2A4 OR4K5 OR8D4	4.30e-19	346	101	19	14611657
Pubmed	Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.	HTR2C ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.85e-18	13	101	8	22569571
Pubmed	Involvement of neurotransmitters in the action of growth hormone-releasing hormone antagonist on passive avoidance learning.	HTR2C ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.85e-18	13	101	8	22640814
Pubmed	The human olfactory receptor gene family.	OR8J3 OR2A7 OR5AK2 OR5V1 OR2T35 OR5I1 OR10Q1 OR8H1 OR2T2 OR8K3 OR8J1 OR1L3 OR1L1 OR1L8 OR4C3 OR10J5 OR12D2 OR2A4 OR4K5 OR8D4	1.01e-16	541	101	20	14983052
Pubmed	Dissociation of heterotrimeric g proteins in cells.	OXER1 DRD3 HTR7 F2R OPRK1 OPRL1 OPRM1 GNRHR2 ADORA3 P2RY4 CXCR6 LPAR6 MTNR1A C3AR1	1.90e-16	179	101	14	18577758
Pubmed	GABAA receptor signaling in caudal periaqueductal gray regulates maternal aggression and maternal care in mice.	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.16e-16	6	101	6	20457185
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	DRD3 HTR2C HTR7 TAAR5 OPRK1 OPRL1 OPRM1 GNRHR2 ADORA3 ADRA1A P2RY4 CXCR6 LPAR6	2.66e-14	200	101	13	18240029
Pubmed	Review: Central non-glucocorticoid inhibitors of the hypothalamo-pituitary-adrenal axis.	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.36e-13	11	101	6	9924185
Pubmed	Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.	OPRK1 OPRL1 OPRM1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.24e-12	81	101	9	22723691
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	HTR2C HTR7 CHRND OPRK1 OPRM1 GNRHR2 ADORA3 ADRA1A GABRA1 GABRA2 GABRA3 GABRA5 GABRA6	4.67e-12	300	101	13	19086053
Pubmed	Genetical genomic determinants of alcohol consumption in rats and humans.	DRD3 HTR2C OPRK1 OPRL1 OPRM1 ADRA1A GABRA2 GABRA3 GABRA4 GABRA6	5.40e-12	130	101	10	19874574
Pubmed	Association study of 182 candidate genes in anorexia nervosa.	DRD3 HTR2C HTR7 OPRK1 OPRM1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	6.28e-12	182	101	11	20468064
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	9.31e-12	18	101	6	19078961
Pubmed	gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties.	GABRA1 GABRA2 GABRA3 GABRA4 GABRA6	1.04e-11	8	101	5	8175718
Pubmed	Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.70e-11	21	101	6	25708312
Pubmed	Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype.	GABRA1 GABRA2 GABRA3 GABRA5	6.70e-11	4	101	4	25865415
Pubmed	Region and layer-specific expression of GABAA receptor isoforms and KCC2 in developing cortex.	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5	8.51e-11	11	101	5	38894703
Pubmed	Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors.	GABRA1 GABRA2 GABRA3 GABRA5	3.34e-10	5	101	4	30104684
Pubmed	A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory.	DRD3 HTR2C OPRM1 GABRA1 GABRA3 GABRA5 GABRA6	3.76e-10	58	101	7	11140838
Pubmed	Modelling extracellular domains of GABA-A receptors: subtypes 1, 2, 3, and 5.	GABRA1 GABRA2 GABRA3 GABRA5	1.00e-09	6	101	4	15033447
Pubmed	Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex.	GABRA2 GABRA3 GABRA4 GABRA5	2.33e-09	7	101	4	7560270
Pubmed	Developmental changes in GABA receptor subunit composition within the gonadotrophin-releasing hormone-1 neuronal system.	GABRA1 GABRA2 GABRA3 GABRA6	2.33e-09	7	101	4	16101898
Pubmed	Lamina-specific alterations in cortical GABA(A) receptor subunit expression in schizophrenia.	GABRA1 GABRA2 GABRA3 GABRA5	2.33e-09	7	101	4	20843900
Pubmed	Functional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta.	GABRA1 GABRA2 GABRA5 GABRA6	2.33e-09	7	101	4	17021187
Pubmed	Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO).	GABRA1 GABRA2 GABRA3 GABRA5	2.33e-09	7	101	4	35228700
Pubmed	Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.	GABRA1 GABRA3 GABRA4 GABRA5	4.65e-09	8	101	4	18185516
Pubmed	GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1.	GABRA1 GABRA2 GABRA3 GABRA6	4.65e-09	8	101	4	11528422
Pubmed	Inhibitory synapse dysfunction and epileptic susceptibility associated with KIF2A deletion in cortical interneurons.	GABRA1 GABRA2 GABRA3 GABRA5	1.39e-08	10	101	4	36733270
Pubmed	Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.	GABRA1 GABRA2 GABRA3 GABRA4	1.39e-08	10	101	4	21789198
Pubmed	Specific subtypes of GABAA receptors mediate phasic and tonic forms of inhibition in hippocampal pyramidal neurons.	GABRA1 GABRA2 GABRA3	2.38e-08	3	101	3	16835366
Pubmed	Analysis of the presence and abundance of GABAA receptors containing two different types of alpha subunits in murine brain using point-mutated alpha subunits.	GABRA1 GABRA2 GABRA3	2.38e-08	3	101	3	15304513
Pubmed	The alpha 1, alpha 2, and alpha 3 subunits of GABAA receptors: comparison in seizure-prone and -resistant mice and during development.	GABRA1 GABRA2 GABRA3	2.38e-08	3	101	3	1356407
Pubmed	Specific GABAA circuits for visual cortical plasticity.	GABRA1 GABRA2 GABRA3	2.38e-08	3	101	3	15017002
Pubmed	The biochemical anatomy of cortical inhibitory synapses.	GABRA1 GABRA3 GABRA4 GABRA5	6.56e-08	14	101	4	22768092
Pubmed	Identification of a novel family of G protein-coupled receptor associated sorting proteins.	HTR7 OPRK1 OPRL1 OPRM1	6.56e-08	14	101	4	15086532
Pubmed	Multiple opioid receptor-like genes are identified in diverse vertebrate phyla.	OPRK1 OPRL1 OPRM1	9.49e-08	4	101	3	8941707
Pubmed	Association study between GABA receptor genes and anxiety spectrum disorders.	GABRA2 GABRA3 GABRA6	9.49e-08	4	101	3	19842164
Pubmed	Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.	GABRA1 GABRA2 GABRA3	9.49e-08	4	101	3	25080596
Pubmed	Genetic basis for the psychostimulant effects of nicotine: a quantitative trait locus analysis in AcB/BcA recombinant congenic mice.	DRD3 GABRA1 GABRA6	9.49e-08	4	101	3	16176386
Pubmed	The α1, α2, α3, and γ2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development.	GABRA1 GABRA2 GABRA3	9.49e-08	4	101	3	26518133
Pubmed	Quantitative autoradiographic mapping of the ORL1, mu-, delta- and kappa-receptors in the brains of knockout mice lacking the ORL1 receptor gene.	OPRK1 OPRL1 OPRM1	9.49e-08	4	101	3	11430857
Pubmed	Altered GABA(A) receptor subunit expression and pharmacology in human Angelman syndrome cortex.	GABRA1 GABRA3 GABRA5	9.49e-08	4	101	3	20692323
Pubmed	GABA(A) receptor downregulation in brains of subjects with autism.	GABRA1 GABRA2 GABRA3	9.49e-08	4	101	3	18821008
Pubmed	A common variant in DRD3 receptor is associated with autism spectrum disorder.	DRD3 HTR2C OPRK1 OPRL1 OPRM1 GABRA3 GABRA5	1.00e-07	128	101	7	19058789
Pubmed	GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.	GABRA1 GABRA2 GABRA3 GABRA4	1.99e-07	18	101	4	18985723
Pubmed	New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds.	GABRA1 GABRA2 GABRA5	4.72e-07	6	101	3	21751815
Pubmed	Functional activity of serotoninergic and melatoninergic systems expressed in the skin.	HTR2C HTR7 MTNR1A	4.72e-07	6	101	3	12767050
Pubmed	Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism.	GABRA2 GABRA4 GABRA5	8.25e-07	7	101	3	16080114
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR8J3 OR2T35 OR8K3 OR8J1 OR12D2	2.57e-06	74	101	5	15081110
Pubmed	Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.	OXER1 DRD3 OPRL1 ADORA3 MTNR1A	2.75e-06	75	101	5	2834384
Pubmed	Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder.	GABRA1 GABRA2 GABRA6	2.81e-06	10	101	3	20583128
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR8J3 OR2A7 OR2T2 OR8J1 OR1L8 OR14A2 OR10J4	3.71e-06	219	101	7	12213199
Pubmed	Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease.	GABRA1 GABRA2 GABRA3	5.13e-06	12	101	3	2561974
Pubmed	Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/μ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain.	OPRL1 OPRM1	8.35e-06	2	101	2	23652222
Pubmed	Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C).	OPRK1 OPRL1	8.35e-06	2	101	2	7802669
Pubmed	Pharmacogenetics of treatment in first-episode schizophrenia: D3 and 5-HT2C receptor polymorphisms separately associate with positive and negative symptom response.	DRD3 HTR2C	8.35e-06	2	101	2	15695058
Pubmed	Molecular evidence for the functional role of dopamine D3 receptor in the morphine-induced rewarding effect and hyperlocomotion.	DRD3 OPRM1	8.35e-06	2	101	2	12574430
Pubmed	GABA-A receptor beta3 and alpha5 subunit gene cluster on chromosome 15q11-q13 and bipolar disorder: a genetic association study.	GABRA3 GABRA5	8.35e-06	2	101	2	11378843
Pubmed	Differential roles of GABA(A) receptor subtypes in benzodiazepine-induced enhancement of brain-stimulation reward.	GABRA2 GABRA3	8.35e-06	2	101	2	22763624
Pubmed	Transient expression of GABAA receptor alpha2 and alpha3 subunits in differentiating cerebellar neurons.	GABRA2 GABRA3	8.35e-06	2	101	2	14766194
Pubmed	κ Opioid Receptor 1 Single Nucleotide Polymorphisms were Associated with the Methadone Dosage.	OPRK1 OPRM1	8.35e-06	2	101	2	31940240
Pubmed	Heterodimerization of opioid receptor-like 1 and mu-opioid receptors impairs the potency of micro receptor agonist.	OPRL1 OPRM1	8.35e-06	2	101	2	15748148
Pubmed	Molecular and neuronal substrate for the selective attenuation of anxiety.	GABRA2 GABRA3	8.35e-06	2	101	2	11021797
Pubmed	Differential involvement of the mu and kappa opioid receptors in spatial learning.	OPRK1 OPRM1	8.35e-06	2	101	2	12884965
Pubmed	Involvement of µ-opioid Receptors and κ-opioid Receptors in Itch-related Scratching Behaviour of Imiquimod-induced Psoriasis-like Dermatitis in Mice.	OPRK1 OPRM1	8.35e-06	2	101	2	28512665
Pubmed	The alpha5(H105R) mutation impairs alpha5 selective binding properties by altered positioning of the alpha5 subunit in GABAA receptors containing two distinct types of alpha subunits.	GABRA1 GABRA5	8.35e-06	2	101	2	19457072
Pubmed	Consequences of prenatal exposure to diazepam on the respiratory parameters, respiratory network activity and gene expression of alpha1 and alpha2 subunits of GABA(A) receptor in newborn rat.	GABRA1 GABRA2	8.35e-06	2	101	2	18085262
Pubmed	Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam.	DRD3 GABRA6	8.35e-06	2	101	2	25482686
Pubmed	Neural basis of benzodiazepine reward: requirement for α2 containing GABAA receptors in the nucleus accumbens.	GABRA2 GABRA3	8.35e-06	2	101	2	24553732
Pubmed	Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling.	GABRA1 GABRA2	8.35e-06	2	101	2	21073549
Pubmed	Mu- and kappa-opioids induce the differentiation of embryonic stem cells to neural progenitors.	OPRK1 OPRM1	8.35e-06	2	101	2	16954126
Pubmed	Linking GABA(A) receptor subunits to alcohol-induced conditioned taste aversion and recovery from acute alcohol intoxication.	GABRA2 GABRA3	8.35e-06	2	101	2	23147414
Pubmed	α2-containing GABAA receptors expressed in hippocampal region CA3 control fast network oscillations.	GABRA1 GABRA2	8.35e-06	2	101	2	23109109
Pubmed	Functional expression of the GABA(A) receptor α2 and α3 subunits at synapses between intercalated medial paracapsular neurons of mouse amygdala.	GABRA2 GABRA3	8.35e-06	2	101	2	22666188
Pubmed	Formation of GABAA receptor complexes containing α1 and α5 subunits is paralleling a multiple T-maze learning task in mice.	GABRA1 GABRA5	8.35e-06	2	101	2	27155990
Pubmed	Deletion of mu- and kappa-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior.	OPRK1 OPRM1	8.35e-06	2	101	2	17185983
Pubmed	Association of the dopamine D3 receptor Ser9Gly and of the serotonin 2C receptor gene polymorphisms with tardive dyskinesia in Greeks with chronic schizophrenic disorder.	DRD3 HTR2C	8.35e-06	2	101	2	19106782
Pubmed	Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome.	GABRA1 GABRA3	8.35e-06	2	101	2	23744069
Pubmed	Functional mapping of GABA A receptor subtypes in the amygdala.	GABRA2 GABRA3	8.35e-06	2	101	2	15341600
Pubmed	Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.	GABRA2 GABRA3	8.35e-06	2	101	2	8391122
Pubmed	Testing the silence of mutations: Transcriptomic and behavioral studies of GABA(A) receptor α1 and α2 subunit knock-in mice.	GABRA1 GABRA2	8.35e-06	2	101	2	21056629
Pubmed	Differential stability of the crystallographic interfaces of mu- and kappa-opioid receptors.	OPRK1 OPRM1	8.35e-06	2	101	2	24651466
Pubmed	GABRA1 and GABRA6 gene mutations in idiopathic generalized epilepsy patients.	GABRA1 GABRA6	8.35e-06	2	101	2	34740144
Pubmed	GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis.	GABRA1 GABRA2	8.35e-06	2	101	2	18973555
Pubmed	Morphine can produce analgesia via spinal kappa opioid receptors in the absence of mu opioid receptors.	OPRK1 OPRM1	8.35e-06	2	101	2	16530171
Pubmed	GABAA receptor alpha1 and alpha6 subunits mediate cell surface anchoring in cultured cells.	GABRA1 GABRA6	8.35e-06	2	101	2	15196679
Pubmed	Altered inhibitory synapses in de novo GABRA5 and GABRA1 mutations associated with early onset epileptic encephalopathies.	GABRA1 GABRA5	8.35e-06	2	101	2	31056671
Pubmed	Elevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease.	OPRL1 OPRM1	8.35e-06	2	101	2	30152845
Pubmed	Association of OPRK1 and OPRM1 methylation with mild cognitive impairment in Xinjiang Han and Uygur populations.	OPRK1 OPRM1	8.35e-06	2	101	2	27838450
Pubmed	Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence.	GABRA2 GABRA4	8.35e-06	2	101	2	19207358
Pubmed	Epistatic effects between variants of kappa-opioid receptor gene and A118G of mu-opioid receptor gene increase susceptibility to addiction in Indian population.	OPRK1 OPRM1	8.35e-06	2	101	2	22138325
Pubmed	Genetic association of GABA-A receptor alpha-2 and mu opioid receptor with cocaine cue-reactivity: evidence for inhibitory synaptic neurotransmission involvement in cocaine dependence.	OPRM1 GABRA2	8.35e-06	2	101	2	22882391
Pubmed	Reversal of pathological pain through specific spinal GABAA receptor subtypes.	GABRA2 GABRA3	8.35e-06	2	101	2	18202657
Pubmed	Novel variants in GABAA receptor subunits: A possible association with benzodiazepine resistance in patients with drug-resistant epilepsy.	GABRA2 GABRA5	8.35e-06	2	101	2	36469977
Pubmed	Association between the serotonin 2C receptor gene and tardive dyskinesia in chronic schizophrenia: additive contribution of 5-HT2Cser and DRD3gly alleles to susceptibility.	DRD3 HTR2C	8.35e-06	2	101	2	11140333
Pubmed	Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference.	GABRA2 GABRA5	8.35e-06	2	101	2	26446222
Pubmed	Opioid Receptors in Psoriatic Skin: Relationship with Itch.	OPRK1 OPRM1	8.35e-06	2	101	2	27958613
Interaction	GABRA5 interactions	GABRA1 GABRA3 GABRA5	6.45e-07	5	82	3	int:GABRA5
Interaction	EMP1 interactions	HTR2C SMIM3 RABAC1 OPRM1 LPAR6	6.72e-06	65	82	5	int:EMP1
Interaction	GPRASP1 interactions	HTR7 F2R OPRK1 OPRL1 OPRM1	7.81e-06	67	82	5	int:GPRASP1
Interaction	TMBIM6 interactions	HTR2C NELFCD RB1CC1 CHRND OPRM1 TRPM8	9.98e-06	121	82	6	int:TMBIM6
Interaction	LPCAT3 interactions	HTR2C OPRL1 OPRM1 LPAR6 C3AR1	1.87e-05	80	82	5	int:LPCAT3
Interaction	ATP2B3 interactions	HTR2C ANXA6 OPRL1 CD1B C3AR1	2.65e-05	86	82	5	int:ATP2B3
Interaction	SGCB interactions	HTR2C SMIM3 CHRND CD1B ADRA1A	2.80e-05	87	82	5	int:SGCB
Cytoband	11q12.1	OR8J3 OR5AK2 OR9Q2 OR10Q1 OR8H1 OR8K3 OR8J1	7.46e-08	161	101	7	11q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR8J3 OR5AK2 OR5I1 OR9Q2 OR10Q1 OR8H1 OR8K3 OR8J1	1.03e-06	345	101	8	chr11q12
Cytoband	9q33.2	OR1L3 OR1L1 OR1L8	8.92e-05	39	101	3	9q33.2
Cytoband	2q37.1	CHRND COPS7B TRPM8	4.47e-04	67	101	3	2q37.1
Cytoband	6q23	TAAR5 OR2A4	5.64e-04	16	101	2	6q23
Cytoband	4p12	GABRA2 GABRA4	8.87e-04	20	101	2	4p12
Cytoband	5q33.1	SMIM3 ANXA6	1.50e-03	26	101	2	5q33.1
Cytoband	Ensembl 112 genes in cytogenetic band chr4p12	GABRA2 GABRA4	1.50e-03	26	101	2	chr4p12
Cytoband	1q44	OR2T35 OR2T2 OR14A2	1.88e-03	110	101	3	1q44
Cytoband	5q34	GABRA1 GABRA6	2.28e-03	32	101	2	5q34
Cytoband	1q23.2	OR10J5 OR10J4	2.72e-03	35	101	2	1q23.2
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2T35 OR2T2 OR14A2	2.89e-03	128	101	3	chr1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr9q33	OR1L3 OR1L1 OR1L8	3.57e-03	138	101	3	chr9q33
Cytoband	Ensembl 112 genes in cytogenetic band chr5q34	GABRA1 GABRA6	3.72e-03	41	101	2	chr5q34
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.88e-10	19	88	6	563
GeneFamily	Opioid receptors	OPRK1 OPRL1 OPRM1	4.44e-07	4	88	3	245
GeneFamily	Olfactory receptors, family 8	OR8J3 OR8H1 OR8K3 OR8J1 OR8D4	3.92e-06	49	88	5	155
GeneFamily	Leukotriene receptors	OXER1 CYSLTR1	3.47e-04	6	88	2	204
GeneFamily	Olfactory receptors, family 1	OR1L3 OR1L1 OR1L8	9.66e-04	40	88	3	147
GeneFamily	5-hydroxytryptamine receptors, G protein-coupled	HTR2C HTR7	1.76e-03	13	88	2	170
GeneFamily	Olfactory receptors, family 2	OR2A7 OR2T35 OR2T2 OR2A4	2.25e-03	113	88	4	149
GeneFamily	ATPase phospholipid transporting	ATP8B1 ATP8B2	2.36e-03	15	88	2	1210
GeneFamily	Olfactory receptors, family 10	OR10Q1 OR10J5 OR10J4	4.09e-03	66	88	3	157
Coexpression	GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN	ABCA1 HIVEP2 PSEN2 F2R LNPEP PCNX1 SFT2D2	8.49e-06	200	95	7	M9469
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERCC4 HTR2C SYT10 OPRK1 MAPK15 OR8D4	3.06e-06	176	101	6	ed7ba2a3af3b060dec98b60f09f96000a67f7e63
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GPR101 OPRK1 OPRM1 MTNR1A TRPM8	5.98e-06	113	101	5	feb3c6a7723263d58e5ce020a0097fedfcf78ca8
Computational	Genes in the cancer module 289.	DRD3 OPRK1 CXCR6 LPAR6 C3AR1 GABRA2 GABRA5 GABRA6	1.05e-07	124	51	8	MODULE_289
Computational	Genes in the cancer module 146.	DRD3 HTR2C HTR7 OPRK1 CXCR6 LPAR6 C3AR1	4.63e-07	102	51	7	MODULE_146
Computational	Genes in the cancer module 141.	GABRA1 GABRA2 GABRA5 GABRA6	7.84e-07	16	51	4	MODULE_141
Computational	Vesicular transport / synapse genes.	DRD3 HTR7 CHRND OPRK1 GABRA1 GABRA5	2.24e-06	82	51	6	MODULE_274
Computational	GPCR signaling pathways (immune and neuro).	DRD3 OPRK1 CXCR6 LPAR6 C3AR1 GABRA2	3.87e-06	90	51	6	MODULE_375
Computational	Genes in the cancer module 134.	HTR7 OPRK1 CXCR6 C3AR1	1.12e-05	30	51	4	MODULE_134
Computational	Genes in the cancer module 396.	GABRA2 GABRA3 GABRA6	2.15e-05	12	51	3	MODULE_396
Computational	Neurotransmitter (GABA) receptor.	GABRA2 GABRA5 GABRA6	4.40e-05	15	51	3	MODULE_215
Computational	Ion channels.	GABRA1 GABRA2 GABRA5 GABRA6	3.27e-04	70	51	4	MODULE_316
Computational	Genes in the cancer module 489.	ADRA1A GABRA2 GABRA3	4.53e-04	32	51	3	MODULE_489
Computational	Neighborhood of ARL3	MON2 ERCC4 HTR7 ATP8B1 RB1CC1 OPRL1 GABRA1	5.37e-04	304	51	7	MORF_ARL3
Computational	Neighborhood of FOSL1	MON2 ERCC4 HTR7 ATP8B1 RB1CC1 OPRL1 ADRA1A GABRA1	5.91e-04	406	51	8	MORF_FOSL1
Computational	Genes in the cancer module 288.	OPRK1 CXCR6 C3AR1	6.98e-04	37	51	3	MODULE_288
Computational	Neighborhood of TFDP2	MON2 ERCC4 HTR7 ATP8B1 RB1CC1 OPRL1	7.24e-04	230	51	6	MORF_TFDP2
Computational	Genes in the cancer module 27.	DRD3 OPRK1 OPRM1 ADORA3 CXCR6 LPAR6 C3AR1	1.34e-03	355	51	7	MODULE_27
Computational	Neighborhood of BNIP1	ERCC4 HTR7 ATP8B1 RB1CC1 OPRL1	1.99e-03	190	51	5	MORF_BNIP1
Computational	Neighborhood of RAD51L3	MON2 ERCC4 HTR2C ATP8B1 RB1CC1 ADRA1A GABRA1	2.19e-03	387	51	7	MORF_RAD51L3
Computational	Neighborhood of CASP10	ERCC4 HTR7 ATP8B1 OPRL1	2.25e-03	117	51	4	MORF_CASP10
Computational	Neighborhood of NOS2A	MON2 ERCC4 HTR7 ATP8B1 RB1CC1 OPRL1	2.30e-03	288	51	6	MORF_NOS2A
Computational	Membranal receptors.	ABCA1 DRD3 HTR7 CHRND OPRK1 CXCR6 LPAR6 C3AR1	2.78e-03	517	51	8	MODULE_64
Computational	Neighborhood of MAGEA9	MON2 ERCC4 HTR2C ATP8B1 RB1CC1 ADRA1A GABRA1	3.60e-03	423	51	7	MORF_MAGEA9
Drug	Meprobamate	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.80e-15	6	99	6	DB00371
Drug	Ethchlorvynol	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.82e-13	9	99	6	DB00189
Drug	Secobarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00418
Drug	Chlordiazepoxide	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00475
Drug	Metharbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00463
Drug	Pentobarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00312
Drug	Talbutal	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00306
Drug	Clobazam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00349
Drug	Butalbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00241
Drug	Butabarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00237
Drug	Bromazepam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB01558
Drug	Barbituric acid derivative	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB01496
Drug	Barbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB01483
Drug	Hexobarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB01355
Drug	Aprobarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB01352
Drug	Amobarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB01351
Drug	Heptabarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB01354
Drug	Butethal	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB01353
Drug	Methylphenobarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00849
Drug	Oxazepam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00842
Drug	Primidone	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00794
Drug	Midazolam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00683
Drug	Flurazepam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.20e-12	10	99	6	DB00690
Drug	benzodiazepine	HTR2C OPRK1 OPRL1 OPRM1 ADORA3 MTNR1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.26e-12	142	99	12	CID000134664
Drug	Thiopental	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-12	11	99	6	DB00599
Drug	Alprazolam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-12	11	99	6	DB00404
Drug	Temazepam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-12	11	99	6	DB00231
Drug	Nitrazepam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-12	11	99	6	DB01595
Drug	Lorazepam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-12	11	99	6	DB00186
Drug	Phenobarbital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-12	11	99	6	DB01174
Drug	Triazolam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-12	11	99	6	DB00897
Drug	Clorazepate	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.63e-12	11	99	6	DB00628
Drug	phentolamine	DRD3 HTR2C HTR7 CHRND OPRK1 OPRL1 OPRM1 SLC5A4 ADORA3 ADRA1A LNPEP GABRA1 GABRA6	4.00e-12	200	99	13	CID000005775
Drug	Flunitrazepam	GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	8.39e-12	6	99	5	DB01544
Drug	atropine sulfate	DRD3 HTR2C HTR7 CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.78e-11	347	99	15	CID000003661
Drug	diazepam	HTR2C TAAR5 OPRK1 OPRL1 OPRM1 ADORA3 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.71e-11	189	99	12	CID000003016
Drug	dihydroxyaflavinine	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	6.90e-11	17	99	6	CID000156857
Drug	AC1Q3ZOL	DRD3 HTR7 CHRND OPRK1 OPRL1 OPRM1 ADORA3 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	9.78e-11	258	99	13	CID000002376
Drug	abecarnil	HTR2C GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.03e-10	18	99	6	CID000065914
Drug	2-hydroxysaclofen	OPRL1 OPRM1 ADRA1A GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.77e-10	59	99	8	CID000001564
Drug	muscimol	DRD3 OPRK1 OPRL1 OPRM1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.44e-10	129	99	10	CID000004266
Drug	pentobarbital	HTR7 OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.67e-10	224	99	12	CID000004737
Drug	DMCM	HTR2C GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	2.68e-10	38	99	7	CID000104999
Drug	zaleplon	MTNR1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.25e-10	39	99	7	CID000005719
Drug	Flumazenil	GABRA1 GABRA2 GABRA3 GABRA5	3.36e-10	4	99	4	DB01205
Drug	AC1L1FKW	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	3.48e-10	10	99	5	CID000003281
Drug	Clonazepam	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5	3.48e-10	10	99	5	DB01068
Drug	Gabrene	DRD3 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.93e-10	40	99	7	CID005361323
Drug	gaboxadol	MTNR1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.72e-10	41	99	7	CID000003448
Drug	tetradotoxin	DRD3 HTR2C HTR7 CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	5.17e-10	428	99	15	CID000020382
Drug	adinazolam	HTR2C GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	5.51e-10	23	99	6	CID000037632
Drug	bretazenil	HTR2C GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	5.51e-10	23	99	6	CID000107926
Drug	fosazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000037114
Drug	C19H18ClN3O	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000027452
Drug	flutoprazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000003400
Drug	Arfendazam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000065803
Drug	camazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000037367
Drug	Bu-1014	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID015942721
Drug	Zapizolam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000068832
Drug	Reclazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID003052777
Drug	iclazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000068777
Drug	menitrazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000189875
Drug	Serin hydrazid	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000041637
Drug	sulazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000017931
Drug	elfazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000065445
Drug	triflubazam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000031157
Drug	uldazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000034274
Drug	gidazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000121919
Drug	fletazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	6.35e-10	11	99	5	CID000036834
Drug	baclofen	DRD3 OPRK1 OPRL1 OPRM1 ADORA3 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	7.19e-10	191	99	11	CID000002284
Drug	alpidem	HTR2C GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	7.32e-10	24	99	6	CID000054897
Drug	methohexital	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	7.32e-10	24	99	6	CID000009034
Drug	AC1Q5UBL	HTR2C OPRK1 OPRL1 ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	8.25e-10	146	99	10	CID000005466
Drug	SB-205384	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.09e-09	12	99	5	CID000197690
Drug	U-93631	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.09e-09	12	99	5	CID000197626
Drug	haloxazolam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.09e-09	12	99	5	CID000003563
Drug	doxefazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.09e-09	12	99	5	CID000038668
Drug	pivoxazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.09e-09	12	99	5	CID000068722
Drug	razobazam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.09e-09	12	99	5	CID000071228
Drug	acamprosate	OPRK1 OPRL1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.14e-09	74	99	8	CID000071158
Drug	pitrazepin	ADRA1A GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.59e-09	27	99	6	CID000146222
Drug	dopamine	DRD3 HTR2C HTR7 TAAR5 F2R CHRND OPRK1 OPRL1 OPRM1 ADORA3 ADRA1A MTNR1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	1.66e-09	715	99	18	CID000000681
Drug	Eszopiclone	GABRA1 GABRA2 GABRA3 GABRA5	1.68e-09	5	99	4	DB00402
Drug	Zopiclone	GABRA1 GABRA2 GABRA3 GABRA5	1.68e-09	5	99	4	DB01198
Drug	Lorazepam	GABRA1 GABRA2 GABRA3 GABRA4	1.68e-09	5	99	4	ctd:D008140
Drug	nerisopam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.76e-09	13	99	5	CID000065875
Drug	flutazolam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.76e-09	13	99	5	CID000003398
Drug	4-PIOL	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.76e-09	13	99	5	CID000125520
Drug	AC1MVFYM	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.76e-09	13	99	5	CID003707225
Drug	Ro 11-3128	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.76e-09	13	99	5	CID000093364
Drug	cinolazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.76e-09	13	99	5	CID003033621
Drug	alpha IMGBL	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.76e-09	13	99	5	CID000131516
Drug	metaclazepam	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	1.76e-09	13	99	5	CID000071272
Drug	beta-CCt	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	2.72e-09	14	99	5	CID000124514
Drug	Me-lex	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	2.72e-09	14	99	5	CID000004177
Drug	ethyl loflazepate	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	2.72e-09	14	99	5	CID000003299
Drug	3-isothujone	GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	3.16e-09	30	99	6	CID000011027
Drug	flumazenil	OPRK1 OPRL1 GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	3.55e-09	54	99	7	CID000003373
Drug	fluoxetine	DRD3 HTR2C HTR7 CHRND ADRA1A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6	4.04e-09	225	99	11	CID000003386
Drug	SR 95103	GABRA1 GABRA2 GABRA4 GABRA5 GABRA6	4.07e-09	15	99	5	CID000125958
Disease	Alcoholic Intoxication, Chronic	DRD3 HTR2C HTR7 OPRK1 OPRL1 OPRM1 GABRA1 GABRA2 GABRA5 GABRA6	1.49e-08	268	94	10	C0001973
Disease	Mood Disorders	DRD3 HTR2C HTR7 OPRK1 GABRA1 GABRA5 GABRA6	1.16e-06	168	94	7	C0525045
Disease	Mental Depression	DRD3 HTR2C HTR7 OPRK1 OPRM1 ARHGEF10 GABRA3 GABRA6	1.59e-06	254	94	8	C0011570
Disease	Cocaine Abuse	DRD3 HTR2C OPRK1 OPRM1 ADRA1A GABRA2	3.37e-06	127	94	6	C0009171
Disease	Depressive disorder	DRD3 HTR2C HTR7 OPRK1 OPRM1 ARHGEF10 GABRA3 GABRA6	4.13e-06	289	94	8	C0011581
Disease	Schizophrenia	ABCA1 DRD3 HTR2C PSEN2 HTR7 RB1CC1 OPRM1 ADRA1A MTNR1A GABRA1 GABRA4 GABRA5 GABRA6	4.55e-06	883	94	13	C0036341
Disease	Visual seizure	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0270824
Disease	Epileptic drop attack	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0270846
Disease	Generalized seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0234533
Disease	Clonic Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0234535
Disease	Vertiginous seizure	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0422855
Disease	Gustatory seizure	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0422854
Disease	Seizures, Somatosensory	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0422850
Disease	Olfactory seizure	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0422853
Disease	Seizures, Auditory	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0422852
Disease	Generalized Absence Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C4505436
Disease	Convulsive Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0751494
Disease	Seizures, Sensory	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0751496
Disease	Jacksonian Seizure	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0022333
Disease	Non-epileptic convulsion	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0751056
Disease	Atonic Absence Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0751123
Disease	Complex partial seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0149958
Disease	Single Seizure	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C0751110
Disease	Epileptic Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C4317109
Disease	Nonepileptic Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.83e-05	101	94	5	C3495874
Disease	Tonic Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.92e-05	102	94	5	C0270844
Disease	Absence Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.92e-05	102	94	5	C4316903
Disease	Convulsions	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	1.92e-05	102	94	5	C4048158
Disease	Seizures, Focal	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	2.11e-05	104	94	5	C0751495
Disease	Myoclonic Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	2.11e-05	104	94	5	C4317123
Disease	Tonic - clonic seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	2.11e-05	104	94	5	C0494475
Disease	Alcohol abuse	DRD3 OPRM1 GABRA1 GABRA2	6.35e-05	67	94	4	C0085762
Disease	Cocaine Dependence	DRD3 OPRK1 OPRM1 ADRA1A GABRA2	8.46e-05	139	94	5	C0600427
Disease	bipolar disorder (is_implicated_in)	HTR2C GABRA3 GABRA5	1.08e-04	29	94	3	DOID:3312 (is_implicated_in)
Disease	Bipolar Disorder	DRD3 HTR2C PSEN2 ADRA1A ARHGEF10 GABRA1 GABRA3 GABRA5	1.45e-04	477	94	8	C0005586
Disease	Autistic Disorder	DRD3 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5	1.92e-04	261	94	6	C0004352
Disease	Morphine Abuse	OPRL1 OPRM1	2.09e-04	7	94	2	C0600272
Disease	Morphine Dependence	OPRL1 OPRM1	2.09e-04	7	94	2	C0026552
Disease	Memory Loss	HTR7 LNPEP GABRA5	3.52e-04	43	94	3	C0751295
Disease	Age-Related Memory Disorders	HTR7 LNPEP GABRA5	3.52e-04	43	94	3	C0751292
Disease	Memory Disorder, Spatial	HTR7 LNPEP GABRA5	3.52e-04	43	94	3	C0751294
Disease	Memory Disorder, Semantic	HTR7 LNPEP GABRA5	3.52e-04	43	94	3	C0751293
Disease	Memory Disorders	HTR7 LNPEP GABRA5	3.52e-04	43	94	3	C0025261
Disease	heroin abuse	OPRM1 GABRA2	3.56e-04	9	94	2	C0600241
Disease	Heroin Dependence	OPRM1 GABRA2	3.56e-04	9	94	2	C0019337
Disease	amnestic disorder (implicated_via_orthology)	DRD3 HTR7	3.56e-04	9	94	2	DOID:10914 (implicated_via_orthology)
Disease	Heroin Smoking	OPRM1 GABRA2	3.56e-04	9	94	2	C4505390
Disease	Memory impairment	HTR7 LNPEP GABRA5	3.77e-04	44	94	3	C0233794
Disease	Cocaine-Related Disorders	DRD3 OPRK1 OPRM1 GABRA2	5.44e-04	117	94	4	C0236736
Disease	autistic disorder (is_marker_for)	GABRA4 GABRA5	6.49e-04	12	94	2	DOID:12849 (is_marker_for)
Disease	Seizures	DRD3 SLC30A1 OPRK1 OPRM1 GABRA5	6.77e-04	218	94	5	C0036572
Disease	HOMA-B	ABCA1 FRK ARHGEF10	7.28e-04	55	94	3	EFO_0004469
Disease	Hepatic Encephalopathy	OPRM1 GABRA1	7.65e-04	13	94	2	C0019151
Disease	Hepatic Coma	OPRM1 GABRA1	7.65e-04	13	94	2	C0019147
Disease	Fulminant Hepatic Failure with Cerebral Edema	OPRM1 GABRA1	7.65e-04	13	94	2	C0751197
Disease	Hepatic Stupor	OPRM1 GABRA1	7.65e-04	13	94	2	C0751198
Disease	Withdrawal Symptoms	HTR2C OPRK1 OPRL1	8.51e-04	58	94	3	C0087169
Disease	Drug Withdrawal Symptoms	HTR2C OPRK1 OPRL1	8.51e-04	58	94	3	C0086189
Disease	Substance Withdrawal Syndrome	HTR2C OPRK1 OPRL1	8.51e-04	58	94	3	C0038587
Disease	Neuralgia, Supraorbital	HTR2C OPRM1	1.17e-03	16	94	2	C0038870
Disease	Neuralgia, Iliohypogastric Nerve	HTR2C OPRM1	1.17e-03	16	94	2	C0423712
Disease	Neuralgia, Perineal	HTR2C OPRM1	1.17e-03	16	94	2	C0423711
Disease	Tremor, Rubral	GABRA1 GABRA4	1.17e-03	16	94	2	C0750940
Disease	Ataxia, Appendicular	GABRA1 GABRA4	1.17e-03	16	94	2	C0750937
Disease	Neuralgia	HTR2C OPRM1	1.17e-03	16	94	2	C0027796
Disease	Ataxia, Motor	GABRA1 GABRA4	1.17e-03	16	94	2	C0278161
Disease	alcohol use disorder (is_implicated_in)	HTR7 GABRA2	1.17e-03	16	94	2	DOID:1574 (is_implicated_in)
Disease	Abnormal coordination	GABRA1 GABRA4	1.17e-03	16	94	2	C0520966
Disease	Ataxia, Truncal	GABRA1 GABRA4	1.17e-03	16	94	2	C0427190
Disease	Neuralgia, Atypical	HTR2C OPRM1	1.17e-03	16	94	2	C0234247
Disease	Neuralgia, Stump	HTR2C OPRM1	1.17e-03	16	94	2	C0234249
Disease	Paroxysmal Nerve Pain	HTR2C OPRM1	1.17e-03	16	94	2	C0751373
Disease	Nerve Pain	HTR2C OPRM1	1.17e-03	16	94	2	C0751372
Disease	Neuralgia, Ilioinguinal	HTR2C OPRM1	1.17e-03	16	94	2	C0751371
Disease	Neuralgia, Vidian	HTR2C OPRM1	1.17e-03	16	94	2	C0042656
Disease	Ataxia, Sensory	GABRA1 GABRA4	1.17e-03	16	94	2	C0240991
Disease	retinopathy	OR5V1 SLC30A1	1.32e-03	17	94	2	EFO_0003839
Disease	Cannabis Dependence	ADRA1A GABRA2	1.32e-03	17	94	2	C0006870
Disease	Parkinson's disease (implicated_via_orthology)	DRD3 OPRK1 OPRL1 OPRM1	1.62e-03	157	94	4	DOID:14330 (implicated_via_orthology)
Disease	nose morphology measurement, mouth morphology measurement	OR8D4 TTLL13	2.03e-03	21	94	2	EFO_0007843, EFO_0007955
Disease	anxiety disorder (implicated_via_orthology)	HTR2C HTR7	2.23e-03	22	94	2	DOID:2030 (implicated_via_orthology)
Disease	Etat Marbre	DRD3 OPRM1	2.43e-03	23	94	2	C0266487
Disease	fasting blood glucose measurement, HOMA-B, fasting blood insulin measurement	OR1L3 OR1L1	2.87e-03	25	94	2	EFO_0004465, EFO_0004466, EFO_0004469
Disease	Cardiac Arrhythmia	OPRK1 OPRL1	2.87e-03	25	94	2	C0003811
Disease	Ataxia	GABRA1 GABRA4	2.87e-03	25	94	2	C0004134

Protein segments in the cluster

Peptide	Gene	Start	Entry
RLCLFVVTPVMVVGT	CHRND	471	Q07001
FNVESRILCMLYVPV	ARHGEF10	951	O15013
FLPLLTMIVCYSVII	CXCR6	201	O00574
IVSLASRMKCIPYSV	COPS7B	101	Q9H9Q2
IFIPLVVMCAIYLDI	ADORA3	186	P0DMS8
PLAIILVMYCRVYVV	ADRA1A	196	P35348
CPRTIEVLMNTYSVV	ASB10	376	Q8WXI3
DMCNYVVPATLVIII	ABCA1	1706	O95477
PLTIMVITYCLTIYV	HTR2C	226	P28335
GIMETVRILLYETCP	CD1B	171	P29016
LLPSVIMIACYSFIV	C3AR1	346	Q16581
YPAIAIVIVLLVMCV	DISP1	506	Q96F81
CLLPVVAIRFLSMTI	ATP8B1	1156	O43520
LMLAVVKCIRSTPEY	ANXA6	241	P08133
LTTVVCIMPVVAFRF	ATP8B2	1091	P98198
VAICNPLLYTVVMSR	OR5I1	126	Q13606
VLAVYSSRLVMVEPV	CAPN15	931	O75808
TVPQMYCLAVVEVVR	RB1CC1	491	Q8TDY2
TAVMIIAYHTVCTPR	NUP210	1821	Q8TEM1
MIQVLYFLEPVRCLI	PAN2	531	Q504Q3
ICYSSAIIPQMLAVL	OR9Q2	71	Q8NGE9
VMPACILVILVSYLF	OR9Q2	206	Q8NGE9
DRVVSVLYTVVTPML	OR9Q2	271	Q8NGE9
ICSPLLYRVIMSPRV	OR8D4	126	Q8NGM9
LYRVIMSPRVCSLLV	OR8D4	131	Q8NGM9
ITIMALYSIVCVVGL	OPRM1	71	P35372
QLSIMDTIYICITVP	OR2T2	66	Q6IF00
RSVMSLIDVVAILPY	KCND1	261	Q9NSA2
IPLAVITTCIVLYMN	CD58	221	P19256
LSTLYQCIRFPVVAM	NELFCD	411	Q8IXH7
MCTVVDPRIVRRYLL	MAPK15	1	Q8TD08
VYRSVVCPILDEVIM	KIF11	81	P52732
TYIVAAPMTTRVLII	LRRC53	26	A6NM62
IVLTIVLYPSRVRVM	ASB17	181	Q8WXJ9
QTYLPCIMTVILSQV	GABRA2	256	P47869
TMIIVAVYCPVIAAV	PCNX1	56	Q96RV3
ICKPLYYVVIMSRRT	OR4K5	126	Q8NGD3
VILIILIVVMARYCR	PCDH7	891	O60245
RCLTKYSQIPSVLVM	ERAL1	221	O75616
PLSVKIVMTYRLCSE	DNAH12	1401	Q6ZR08
SLVIYVICRHKPMRT	KISS1R	61	Q969F8
MALRICVTYTPALPI	MYEOV	1	Q96EZ4
PSARTMVVCAFVIVV	LNPEP	106	Q9UIQ6
AVSVIMVIYLLPRCT	LNPEP	121	Q9UIQ6
QTYLPCIMTVILSQV	GABRA3	281	P34903
QTYLPCIMTVILSQV	GABRA1	256	P14867
IQTYIPCIMTVILSQ	GABRA4	261	P48169
VIQTYLPCIMTVILS	GABRA5	261	P31644
QIYTPCIMTVILSQV	GABRA6	246	Q16445
VYMPTVVLRRTPACA	IL17D	136	Q8TAD2
VAAVRTMYPITLCIA	LPAR6	266	P43657
YVVILCPTEMDVQVR	KCNT2	331	Q6UVM3
IVIPLIVMIACYSVV	GPR101	201	Q96P66
YFPICMRLLRVVSVL	MON2	306	Q7Z3U7
LVGPLSTIVVSYMCI	OR2A7	206	Q96R45
RIVAIMYTVVTPVLN	OR12D2	271	P58182
QLSIMDTIYICITVP	OR2T35	66	Q8NGX2
ICNPLLYMVVVSRRL	OR8J3	126	Q8NGG0
VLAMVVAVYTICFLP	OXER1	296	Q8TDS5
VIMTPFSCIIISYLR	OR1L1	256	Q8NH94
LVGPLSTIVVSYMCI	OR2A4	206	O95047
VPLIISTVCYVSIIR	F2R	281	P25116
DRLVSVLYSVVTPML	OR5V1	271	Q9UGF6
VPCLVTLVCYGLMAR	P2RY4	211	P51582
ICKPLHYTVIMSRTV	OR5AK2	126	Q8NH90
ICNPLLYMVVVSRRL	OR8J1	126	Q8NGP2
CTLEDPIYIITELMR	FRK	296	P42685
ICLLVAYITENLMRP	FNDC10	201	F2Z333
CLPYAITIVASMTVR	DHX37	796	Q8IY37
LCAISIDRYTAVVMP	DRD3	121	P35462
YPVIMSKRLCCALVT	OR8H1	131	Q8NGG4
SVMAPFVCIIISYLR	OR1L3	206	Q8NH93
CVLVLPMVLIFISYV	OR10J4	206	P0C629
TVYTLVIVPRMLLSL	OR10J5	71	Q8NHC4
MTEAPIVLVTRFLCI	OR1L8	201	Q8NGR8
CYTTVVVPLMLSNIL	OR10Q1	76	Q8NGQ4
VIPVLIIIVCYTLMI	OPRK1	236	P41145
VPVLVISVCYSLMIR	OPRL1	226	P41146
SVIDRLLSVIYTVMP	OR14A2	266	Q96R54
LIYVVTVCGNMLIVV	OR4C3	31	Q8NH37
PCLIMISLYVKIFVV	TAAR5	211	O14804
PTRLIATIMVLLCFA	SFT2D2	96	O95562
LPTLLIAECVLVYMT	LCMT1	191	Q9UIC8
VCTRKEYLTMSLPEV	NBEAL2	656	Q6ZNJ1
LLPLTAMAICYSRIV	GNRHR2	126	Q96P88
RILYTDMVACVVPSE	SLC5A4	336	Q9NY91
AITADILMYVVIPTR	SPNS2	441	Q8IVW8
ILMYVVIPTRRATAV	SPNS2	446	Q8IVW8
YTTIMRPSVCIGTVV	OR6J1	131	Q8NGC5
ICNPLLYTVIMSRRV	OR8K3	126	Q8NH51
LYTVIMSRRVCQVLV	OR8K3	131	Q8NH51
LVLIAVMLVSRTYCD	ABCD3	86	P28288
MTLCVISIDRYLGIT	HTR7	171	P34969
PFVIIIVCYTMIILT	CYSLTR1	201	Q9Y271
QCYIDPSLTVLMVII	SLC30A10	276	Q6XR72
SLLLCPATAVIIYRM	SMIM3	36	Q9BZL3
LFVPVTLCMIVVVAT	PSEN2	91	P49810
LCYLPTAGRMTLTVI	SYT10	371	Q6XYQ8
ILYCVVTSPMLLVAL	RABAC1	86	Q9UI14
TPLYACELCATVMRI	ZNF469	3371	Q96JG9
YILTPEMCVERKSIS	ERCC4	716	Q92889
TIPLVCIYMLSTNIL	TRPM8	956	Q7Z2W7
CVVMVCILLYTTYPL	SLC30A1	321	Q9Y6M5
YLVTLPSIRVTQLMT	HIVEP2	1971	P31629
MRVYVLITSCDPLRI	TTLL13	246	A6NNM8
PVGVLYIRSCRVLML	JKAMP	111	Q9P055
FLVPMIIVIFCYLRI	MTNR1A	196	P48039