Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cupric reductase (NADH) activity	STEAP1B STEAP3 STEAP1	3.43e-09	5	15	3	GO:0008823
GeneOntologyMolecularFunction	ferric-chelate reductase (NADPH) activity	STEAP1B STEAP3 STEAP1	3.43e-09	5	15	3	GO:0052851
GeneOntologyMolecularFunction	ferric-chelate reductase activity	STEAP1B STEAP3 STEAP1	3.43e-09	5	15	3	GO:0000293
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor	STEAP1B STEAP3 STEAP1	1.20e-08	7	15	3	GO:0016723
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions	STEAP1B STEAP3 STEAP1	2.78e-07	18	15	3	GO:0016722
GeneOntologyMolecularFunction	heme binding	STEAP1B STEAP3 STEAP1	1.91e-04	154	15	3	GO:0020037
GeneOntologyMolecularFunction	tetrapyrrole binding	STEAP1B STEAP3 STEAP1	2.30e-04	164	15	3	GO:0046906
GeneOntologyBiologicalProcess	iron ion import across cell outer membrane	STEAP1B STEAP3 STEAP1	2.49e-09	5	14	3	GO:0098706
GeneOntologyBiologicalProcess	copper ion import	STEAP1B STEAP3 STEAP1	2.09e-08	9	14	3	GO:0015677
GeneOntologyBiologicalProcess	copper ion transport	STEAP1B STEAP3 STEAP1	2.82e-07	20	14	3	GO:0006825
GeneOntologyBiologicalProcess	negative regulation of T cell receptor signaling pathway	PTPRJ BTN2A1 BTN2A2	9.00e-07	29	14	3	GO:0050860
GeneOntologyBiologicalProcess	iron ion transmembrane transport	STEAP1B STEAP3 STEAP1	1.00e-06	30	14	3	GO:0034755
GeneOntologyBiologicalProcess	negative regulation of antigen receptor-mediated signaling pathway	PTPRJ BTN2A1 BTN2A2	2.07e-06	38	14	3	GO:0050858
GeneOntologyBiologicalProcess	regulation of T cell receptor signaling pathway	PTPRJ BTN2A1 BTN2A2	6.40e-06	55	14	3	GO:0050856
GeneOntologyBiologicalProcess	iron ion transport	STEAP1B STEAP3 STEAP1	1.16e-05	67	14	3	GO:0006826
GeneOntologyBiologicalProcess	regulation of antigen receptor-mediated signaling pathway	PTPRJ BTN2A1 BTN2A2	1.77e-05	77	14	3	GO:0050854
GeneOntologyBiologicalProcess	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	PTPRJ BTN2A1 BTN2A2	2.46e-05	86	14	3	GO:0051898
GeneOntologyBiologicalProcess	transition metal ion transport	STEAP1B STEAP3 STEAP1	5.58e-05	113	14	3	GO:0000041
GeneOntologyBiologicalProcess	negative regulation of activated T cell proliferation	BTN2A1 BTN2A2	8.07e-05	20	14	2	GO:0046007
GeneOntologyBiologicalProcess	T cell receptor signaling pathway	PTPRJ BTN2A1 BTN2A2	1.57e-04	160	14	3	GO:0050852
GeneOntologyBiologicalProcess	positive regulation of regulatory T cell differentiation	BTN2A1 BTN2A2	1.97e-04	31	14	2	GO:0045591
GeneOntologyBiologicalProcess	negative regulation of MAPK cascade	PTPRJ BTN2A1 BTN2A2	3.07e-04	201	14	3	GO:0043409
GeneOntologyBiologicalProcess	antigen receptor-mediated signaling pathway	PTPRJ BTN2A1 BTN2A2	4.16e-04	223	14	3	GO:0050851
GeneOntologyBiologicalProcess	regulation of regulatory T cell differentiation	BTN2A1 BTN2A2	4.94e-04	49	14	2	GO:0045589
GeneOntologyBiologicalProcess	regulatory T cell differentiation	BTN2A1 BTN2A2	6.00e-04	54	14	2	GO:0045066
GeneOntologyBiologicalProcess	regulation of activated T cell proliferation	BTN2A1 BTN2A2	6.00e-04	54	14	2	GO:0046006
GeneOntologyBiologicalProcess	activated T cell proliferation	BTN2A1 BTN2A2	8.68e-04	65	14	2	GO:0050798
GeneOntologyBiologicalProcess	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	PTPRJ BTN2A1 BTN2A2	1.34e-03	334	14	3	GO:0051896
GeneOntologyBiologicalProcess	immune response-activating cell surface receptor signaling pathway	PTPRJ BTN2A1 BTN2A2	1.65e-03	359	14	3	GO:0002429
GeneOntologyBiologicalProcess	negative regulation of ERK1 and ERK2 cascade	BTN2A1 BTN2A2	1.84e-03	95	14	2	GO:0070373
GeneOntologyBiologicalProcess	negative regulation of G1/S transition of mitotic cell cycle	BTN2A1 BTN2A2	1.96e-03	98	14	2	GO:2000134
GeneOntologyBiologicalProcess	phosphatidylinositol 3-kinase/protein kinase B signal transduction	PTPRJ BTN2A1 BTN2A2	1.97e-03	382	14	3	GO:0043491
GeneOntologyBiologicalProcess	positive regulation of immune response	PTPRJ BTN2A1 BTN2A2 TRIM62	2.01e-03	845	14	4	GO:0050778
GeneOntologyBiologicalProcess	immune response-regulating cell surface receptor signaling pathway	PTPRJ BTN2A1 BTN2A2	2.14e-03	393	14	3	GO:0002768
GeneOntologyBiologicalProcess	negative regulation of T cell proliferation	BTN2A1 BTN2A2	2.33e-03	107	14	2	GO:0042130
GeneOntologyBiologicalProcess	negative regulation of cell cycle G1/S phase transition	BTN2A1 BTN2A2	2.42e-03	109	14	2	GO:1902807
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	STEAP1B SLC24A1 STEAP3 STEAP1	2.77e-03	922	14	4	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	STEAP1B SLC24A1 STEAP3 STEAP1	3.00e-03	942	14	4	GO:0098655
GeneOntologyBiologicalProcess	negative regulation of lymphocyte proliferation	BTN2A1 BTN2A2	3.11e-03	124	14	2	GO:0050672
GeneOntologyBiologicalProcess	positive regulation of cell activation	PTPRJ BTN2A1 BTN2A2	3.12e-03	449	14	3	GO:0050867
GeneOntologyBiologicalProcess	negative regulation of mononuclear cell proliferation	BTN2A1 BTN2A2	3.21e-03	126	14	2	GO:0032945
MousePheno	increased response to antigen	BTN2A1 BTN2A2	8.43e-06	6	11	2	MP:0020002
MousePheno	increased IgG2c level	BTN2A1 BTN2A2	3.08e-05	11	11	2	MP:0008896
MousePheno	abnormal IgG2c level	BTN2A1 BTN2A2	1.17e-04	21	11	2	MP:0020178
Domain	Fe3_Rdtase_TM_dom	STEAP1B STEAP3 STEAP1	9.18e-08	12	15	3	IPR013130
Domain	Ferric_reduct	STEAP1B STEAP3 STEAP1	9.18e-08	12	15	3	PF01794
Domain	PRY	BTN2A1 BTN2A2 TRIM62	4.72e-06	42	15	3	PF13765
Domain	PRY	BTN2A1 BTN2A2 TRIM62	7.09e-06	48	15	3	SM00589
Domain	PRY	BTN2A1 BTN2A2 TRIM62	7.09e-06	48	15	3	IPR006574
Domain	Butyrophylin	BTN2A1 BTN2A2 TRIM62	2.22e-05	70	15	3	IPR003879
Domain	SPRY	BTN2A1 BTN2A2 TRIM62	4.27e-05	87	15	3	SM00449
Domain	SPRY	BTN2A1 BTN2A2 TRIM62	5.38e-05	94	15	3	PF00622
Domain	SPRY_dom	BTN2A1 BTN2A2 TRIM62	5.38e-05	94	15	3	IPR003877
Domain	B30.2/SPRY	BTN2A1 BTN2A2 TRIM62	5.55e-05	95	15	3	IPR001870
Domain	B302_SPRY	BTN2A1 BTN2A2 TRIM62	5.55e-05	95	15	3	PS50188
Domain	Actin/actin-like_CS	ACTRT3 ACTBL2	9.14e-05	18	15	2	IPR020902
Domain	ACTINS_ACT_LIKE	ACTRT3 ACTBL2	1.02e-04	19	15	2	PS01132
Domain	ACTIN	ACTRT3 ACTBL2	2.76e-04	31	15	2	SM00268
Domain	Actin	ACTRT3 ACTBL2	2.76e-04	31	15	2	IPR004000
Domain	Actin	ACTRT3 ACTBL2	2.76e-04	31	15	2	PF00022
Domain	CD80_C2-set	BTN2A1 BTN2A2	4.85e-04	41	15	2	IPR013162
Domain	C2-set_2	BTN2A1 BTN2A2	4.85e-04	41	15	2	PF08205
Domain	ConA-like_dom	BTN2A1 BTN2A2 TRIM62	6.52e-04	219	15	3	IPR013320
Domain	IGv	BTN2A1 BTN2A2	1.62e-03	75	15	2	SM00406
Domain	V-set	BTN2A1 BTN2A2	9.32e-03	184	15	2	PF07686
Domain	Ig_V-set	BTN2A1 BTN2A2	1.08e-02	199	15	2	IPR013106
Domain	-	PTPRJ BTN2A1 BTN2A2	1.47e-02	663	15	3	2.60.40.10
Domain	Ig-like_fold	PTPRJ BTN2A1 BTN2A2	1.74e-02	706	15	3	IPR013783
Pathway	REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS	BTN2A1 BTN2A2	2.38e-05	9	12	2	MM15487
Pathway	REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS	BTN2A1 BTN2A2	4.36e-05	12	12	2	M27738
Pathway	WP_COPPER_HOMEOSTASIS	STEAP3 STEAP1	8.94e-04	53	12	2	M39349
Pubmed	The Steap proteins are metalloreductases.	STEAP1B STEAP3 STEAP1	6.49e-10	5	15	3	16609065
Pubmed	Cloning and characterization of a novel six-transmembrane protein STEAP2, expressed in normal and malignant prostate.	STEAP1B STEAP3 STEAP1	6.49e-10	5	15	3	12429817
Pubmed	Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.	STEAP1B STEAP1	1.74e-07	2	15	2	37209327
Pubmed	Characterization of a single b-type heme, FAD, and metal binding sites in the transmembrane domain of six-transmembrane epithelial antigen of the prostate (STEAP) family proteins.	STEAP3 STEAP1	1.74e-07	2	15	2	26205815
Pubmed	Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal stem cells.	STEAP1B STEAP1	5.21e-07	3	15	2	19196137
Pubmed	Inhibition of mouse RM-1 prostate cancer and B16F10 melanoma by the fusion protein of HSP65 & STEAP1 186-193.	STEAP1B STEAP1	5.21e-07	3	15	2	30841425
Pubmed	Molecular cloning and characterization of STAMP1, a highly prostate-specific six transmembrane protein that is overexpressed in prostate cancer.	STEAP3 STEAP1	5.21e-07	3	15	2	12095985
Pubmed	RANKL-Induced Btn2a2 - A T Cell Immunomodulatory Molecule - During Osteoclast Differentiation Fine-Tunes Bone Resorption.	BTN2A1 BTN2A2	5.21e-07	3	15	2	34421818
Pubmed	Butyrophilin 2a2 (Btn2a2) expression on thymic epithelial cells promotes central T cell tolerance and prevents autoimmune disease.	BTN2A1 BTN2A2	5.21e-07	3	15	2	37356345
Pubmed	Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice.	STEAP1B STEAP1	5.21e-07	3	15	2	11479226
Pubmed	Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes.	BTN2A1 BTN2A2	1.04e-06	4	15	2	26809444
Pubmed	Predictive potential of STEAP family for survival, immune microenvironment and therapy response in glioma.	STEAP3 STEAP1	1.04e-06	4	15	2	34649092
Pubmed	Btn2a2 Regulates ILC2-T Cell Cross Talk in Type 2 Immune Responses.	BTN2A1 BTN2A2	1.04e-06	4	15	2	35145516
Pubmed	Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes.	BTN2A1 BTN2A2	1.04e-06	4	15	2	23589618
Pubmed	BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.	BTN2A1 BTN2A2	2.60e-06	6	15	2	20208008
Pubmed	The cluster of BTN genes in the extended major histocompatibility complex.	BTN2A1 BTN2A2	3.64e-06	7	15	2	11170752
Pubmed	A 1.1-Mb transcript map of the hereditary hemochromatosis locus.	BTN2A1 BTN2A2	2.65e-05	18	15	2	9149941
Pubmed	Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.	STEAP1B STEAP1	1.48e-04	42	15	2	23863479
Interaction	STEAP1B interactions	STEAP1B STEAP1	3.10e-06	4	15	2	int:STEAP1B
Interaction	STEAP1 interactions	STEAP1B STEAP1	1.44e-05	8	15	2	int:STEAP1
Interaction	OR13G1 interactions	COMMD8 ACTBL2	1.30e-04	23	15	2	int:OR13G1
Interaction	TNFRSF10A interactions	STEAP3 BTN2A1 BTN2A2	1.32e-04	137	15	3	int:TNFRSF10A
Interaction	NDUFA4L2 interactions	COMMD8 ACTBL2	1.80e-04	27	15	2	int:NDUFA4L2
Interaction	LCTL interactions	STEAP3 BTN2A2	1.80e-04	27	15	2	int:LCTL
Interaction	SLC14A1 interactions	TMIE BTN2A2	2.69e-04	33	15	2	int:SLC14A1
Interaction	TMEFF1 interactions	PTPRJ STEAP3	3.39e-04	37	15	2	int:TMEFF1
Cytoband	6p22.1	BTN2A1 BTN2A2	9.71e-04	142	15	2	6p22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr6p22	BTN2A1 BTN2A2	6.61e-03	378	15	2	chr6p22
GeneFamily	Proteases, serine\|STEAP family	STEAP1B STEAP3 STEAP1	2.90e-09	5	13	3	1324
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN2A1 BTN2A2	4.98e-05	15	13	2	458
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	BTN2A1 BTN2A2	3.67e-04	40	13	2	592
GeneFamily	Adenosine receptors\|V-set domain containing	BTN2A1 BTN2A2	5.90e-03	163	13	2	590
Coexpression	HOLLERN_MICROACINAR_BREAST_TUMOR_DN	STEAP1B STEAP1	3.65e-05	16	15	2	MM969
Coexpression	GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_DN	BTN2A1 LIPE TRIM62	1.75e-04	196	15	3	M5778
Coexpression	GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN	SLC24A1 BTN2A1 BTN2A2	1.83e-04	199	15	3	M3460
Coexpression	GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP	PTPRJ ACTRT3 STEAP3	1.86e-04	200	15	3	M9449
Computational	Genes in the cancer module 322.	BTN2A2 LIPE	8.12e-04	59	8	2	MODULE_322
Drug	Viroisin	ACTRT3 ACTBL2	2.22e-05	11	15	2	CID000119538
Drug	bistheonellide A	ACTRT3 ACTBL2	2.22e-05	11	15	2	CID006441172
Drug	BFDGE	ACTRT3 ACTBL2	2.66e-05	12	15	2	CID000091511
Drug	kabiramide C	ACTRT3 ACTBL2	3.67e-05	14	15	2	CID005288658
Drug	2-arachidonoylglycerol (2-AG	ACTRT3 ACTBL2 LIPE	6.05e-05	119	15	3	CID000001541
Drug	Nsc687160	ACTRT3 ACTBL2	6.16e-05	18	15	2	CID005459290
Drug	5'IATR	ACTRT3 ACTBL2	6.88e-05	19	15	2	CID000074997
Drug	tolytoxin	ACTRT3 ACTBL2	6.88e-05	19	15	2	CID006440827
Drug	AC1L8NVR	ACTRT3 ACTBL2	8.45e-05	21	15	2	CID000384633
Drug	Mgamp-pnp	ACTRT3 ACTBL2	8.45e-05	21	15	2	CID005311323
Drug	NSC312786	ACTRT3 ACTBL2	8.45e-05	21	15	2	CID000329495
Drug	NSC60597	UGT2B7 ACTRT3 ACTBL2	9.81e-05	140	15	3	CID000003327
Drug	Nbd-Ph	ACTRT3 ACTBL2	1.11e-04	24	15	2	CID004682184
Drug	apple polyphenol extract	PTPRJ UGT2B7	1.74e-04	30	15	2	ctd:C526219
Drug	azaspiracid	ACTRT3 ACTBL2	1.74e-04	30	15	2	CID006451158
Drug	Nb d	ACTRT3 ACTBL2 LIPE	1.87e-04	174	15	3	CID000445938
Drug	AC1L1HS4	ACTRT3 ACTBL2	1.99e-04	32	15	2	CID000004267
Drug	deoxynivalenol	PTPRJ UGT2B7 STEAP3 ACTBL2	2.23e-04	481	15	4	ctd:C007262
Drug	N,N'-p-phenylenedimaleimide	ACTRT3 ACTBL2	2.25e-04	34	15	2	CID000076765
Drug	astragaloside A	ACTRT3 ACTBL2	2.25e-04	34	15	2	CID000122690
Drug	1,N6-ethenoadenosine 5'-diphosphate	ACTRT3 ACTBL2	2.25e-04	34	15	2	CID000001312
Drug	Thonzonium bromide [553-08-2]; Up 200; 6.8uM; MCF7; HT_HG-U133A	SLC24A1 BTN2A2 LIPE	2.57e-04	194	15	3	6457_UP
Drug	Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; PC3; HT_HG-U133A	SLC24A1 BTN2A2 TRIM62	2.65e-04	196	15	3	7155_UP
Drug	thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	SLC24A1 STEAP3 TRIM62	2.69e-04	197	15	3	5227_DN
Drug	9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A	SLC24A1 BTN2A1 TRIM62	2.73e-04	198	15	3	7500_DN
Drug	amitriptyline hydrochloride; Up 200; 1uM; MCF7; HG-U133A	COMMD8 BTN2A1 TRIM62	2.77e-04	199	15	3	167_UP
Drug	Methazolamide [554-57-4]; Down 200; 17uM; MCF7; HT_HG-U133A	BTN2A1 BTN2A2 TRIM62	2.77e-04	199	15	3	6268_DN
Drug	celecoxib; Up 200; 10uM; MCF7; HG-U133A	COMMD8 BTN2A1 TRIM62	2.81e-04	200	15	3	377_UP
Drug	4-chloroaniline	ACTRT3 ACTBL2 STEAP1	2.89e-04	202	15	3	CID000007812
Drug	wiskostatin	ACTRT3 ACTBL2	2.96e-04	39	15	2	CID000448668
Drug	epsilon-ATP	ACTRT3 ACTBL2	3.27e-04	41	15	2	CID000162262
Drug	SF6847	ACTRT3 ACTBL2	3.27e-04	41	15	2	CID000005614
Drug	KT5926	ACTRT3 ACTBL2	3.44e-04	42	15	2	CID000122126
Drug	N-acetyl-S-geranylgeranyl-L-cysteine	ACTRT3 ACTBL2	3.44e-04	42	15	2	CID000002067
Drug	cryptotanshinone	ACTRT3 ACTBL2	3.60e-04	43	15	2	CID000160254
Drug	AC1L8FNU	ACTRT3 ACTBL2	3.77e-04	44	15	2	CID000425429
Drug	withaferin A	ACTRT3 ACTBL2	4.12e-04	46	15	2	CID000265237
Drug	tetramethylrhodamine isothiocyanate	ACTRT3 ACTBL2	4.31e-04	47	15	2	CID004123009
Drug	NpCaM	ACTRT3 ACTBL2	4.49e-04	48	15	2	CID000122259
Drug	AC1Q6LQU	ACTRT3 ACTBL2	4.49e-04	48	15	2	CID000072380
Drug	tetramethylrhodamine	ACTRT3 ACTBL2	4.87e-04	50	15	2	CID000065219
Drug	monochloramine	ACTRT3 ACTBL2	5.27e-04	52	15	2	CID000025423
Drug	3-methylhistidine	ACTRT3 ACTBL2	5.90e-04	55	15	2	CID000064969
Drug	PTK/ZK	ACTRT3 ACTBL2	6.11e-04	56	15	2	CID000151193
Drug	BADGE	ACTRT3 ACTBL2	6.56e-04	58	15	2	CID000002286
Drug	dihydrocytochalasin B	ACTRT3 ACTBL2	6.56e-04	58	15	2	CID000003064
Drug	NSC350593	PTPRJ ACTRT3 ACTBL2	6.68e-04	269	15	3	CID000004364
Drug	3-OH	UGT2B7 LIPE	7.25e-04	61	15	2	CID000068152
Drug	AC1NSKHI	ACTRT3 ACTBL2	7.25e-04	61	15	2	CID005311358
Drug	glycerophosphoinositol	ACTRT3 ACTBL2	7.49e-04	62	15	2	CID000167572
Drug	oryzalin	ACTRT3 ACTBL2	7.73e-04	63	15	2	CID000029393
Drug	(2R)-2-[(R)-carboxy-[[(2Z)-2-(2-furyl)-2-methoxyimino-acetyl]amino]methyl]-5-methylene-2H-1,3-thiazine-4-carboxylic acid	UGT2B7 LIPE	7.98e-04	64	15	2	CID011987767
Drug	2,5-dihydroxybenzoic acid	ACTRT3 ACTBL2	8.23e-04	65	15	2	CID000003469
Drug	5-IAF	ACTRT3 ACTBL2	8.48e-04	66	15	2	CID000123822
Drug	lithium chromate	SLC24A1 ACTRT3 ACTBL2	8.81e-04	296	15	3	CID000026627
Drug	AC1L1ERT	ACTRT3 ACTBL2	9.26e-04	69	15	2	CID000002920
Drug	thryroxine	UGT2B7 ACTRT3 ACTBL2	9.34e-04	302	15	3	CID000000853
Drug	caged ATP	ACTRT3 ACTBL2	9.53e-04	70	15	2	CID000123806
Disease	testosterone measurement	PTPRJ SLC24A1 UGT2B7 LIPE	2.45e-03	1275	14	4	EFO_0004908
Disease	birth weight, parental genotype effect measurement	STEAP1B PTPRJ	3.64e-03	192	14	2	EFO_0004344, EFO_0005939
Disease	post-traumatic stress disorder	BTN2A1 BTN2A2	4.02e-03	202	14	2	EFO_0001358
Disease	autism spectrum disorder, schizophrenia	BTN2A1 BTN2A2	1.02e-02	327	14	2	EFO_0003756, MONDO_0005090
Disease	sleep duration	STEAP1B PTPRJ	1.24e-02	362	14	2	EFO_0005271
Disease	lung carcinoma	STEAP1B BTN2A1	2.13e-02	482	14	2	EFO_0001071

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSWEDMEIMWKHIYD	ACTRT3	76	Q9BYD9
VVTNWDDMEKIWYHT	ACTBL2	76	Q562R1
IHVVYVTTTEMWLDW	PTPRJ	546	Q12913
YVFTMKWNKHIEVWV	SLC24A1	596	O60721
TDQVLHWVVWVMKEF	GABPA	191	Q06546
HWVVWVMKEFSMTDI	GABPA	196	Q06546
DYHTVWESEEWMHVL	COMMD8	41	Q9NX08
HYWEVEVENVIEWTV	BTN2A1	386	Q7KYR7
KHYWEVEVENVMVWT	BTN2A2	381	Q8WVV5
VHFWKAFWNITEMEV	LIPE	536	Q05469
DAWIEHDVWRMEIYV	STEAP1	206	Q9UHE8
EDAWIEHDVWRMEIY	STEAP1B	186	Q6NZ63
SHLWVEEEVWRMEIY	STEAP3	346	Q658P3
KETVVFWDMRLWHVV	TMIE	46	Q8NEW7
VLVWAAEYSHWMNIK	UGT2B7	26	P16662
HYWEVVVAEKTQWVI	TRIM62	351	Q9BVG3