Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionAMPA glutamate receptor activity

GRIA2 GRIA3

9.02e-064252GO:0004971
GeneOntologyMolecularFunctionfrizzled binding

WNT3 WNT6 WNT16

1.93e-0542253GO:0005109
GeneOntologyMolecularFunctionglucosidase activity

GBA3 GANAB

1.56e-0415252GO:0015926
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA2 GRIA3

2.02e-0417252GO:0004970
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA2 GRIA3

4.08e-0424252GO:0099507
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA2 GRIA3

5.18e-0427252GO:0008066
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

UBA3 ACSS1

1.20e-0341252GO:0016877
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIA2 GRIA3

2.30e-0357252GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIA2 GRIA3

2.55e-0360252GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIA2 GRIA3

2.98e-0365252GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIA2 GRIA3

2.98e-0365252GO:0022824
GeneOntologyMolecularFunctioncytokine activity

WNT3 WNT6 WNT16

3.64e-03250253GO:0005125
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIA2 GRIA3

3.95e-0375252GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIA2 GRIA3

4.16e-0377252GO:0005230
GeneOntologyMolecularFunctionreceptor ligand activity

ANGPTL3 WNT3 WNT6 WNT16

4.46e-03547254GO:0048018
GeneOntologyMolecularFunctionsignaling receptor activator activity

ANGPTL3 WNT3 WNT6 WNT16

4.67e-03554254GO:0030546
GeneOntologyMolecularFunctioncargo receptor activity

SSC5D LRP1B

5.04e-0385252GO:0038024
GeneOntologyMolecularFunctionscaffold protein binding

GRIA2 CIT

6.00e-0393252GO:0097110
GeneOntologyMolecularFunctionATP-dependent activity

UBA3 CPOX ACSS1 NAIP

6.70e-03614254GO:0140657
GeneOntologyMolecularFunctionsignaling receptor regulator activity

ANGPTL3 WNT3 WNT6 WNT16

6.77e-03616254GO:0030545
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRIA2 GRIA3

6.91e-03100252GO:0030594
GeneOntologyMolecularFunctionamyloid-beta binding

GRIA2 GRIA3

7.18e-03102252GO:0001540
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

GBA3 GANAB

7.32e-03103252GO:0004553
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIA2 GRIA3

7.59e-03105252GO:0015171
GeneOntologyMolecularFunctionG protein-coupled receptor binding

WNT3 WNT6 WNT16

8.32e-03337253GO:0001664
GeneOntologyMolecularFunctionPDZ domain binding

GRIA2 CIT

1.03e-02123252GO:0030165
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

GRIA2 GRIA3

1.32e-02140252GO:0099094
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

GBA3 GANAB

1.39e-02144252GO:0016798
GeneOntologyCellularComponentendocytic vesicle membrane

GRIA2 GRIA3 WNT3 WNT6

1.10e-04212254GO:0030666
GeneOntologyCellularComponentAMPA glutamate receptor complex

GRIA2 GRIA3

5.85e-0430252GO:0032281
GeneOntologyCellularComponentextracellular matrix

ANGPTL3 SSC5D ADAMTS1 WNT3 WNT6

9.45e-04656255GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ANGPTL3 SSC5D ADAMTS1 WNT3 WNT6

9.58e-04658255GO:0030312
GeneOntologyCellularComponentendocytic vesicle

GRIA2 GRIA3 WNT3 WNT6

1.04e-03384254GO:0030139
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIA2 GRIA3

1.32e-0345252GO:0008328
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIA2 GRIA3

1.62e-0350252GO:0098878
GeneOntologyCellularComponentperikaryon

GRIA2 GRIA3 NAIP

2.32e-03223253GO:0043204
GeneOntologyCellularComponentcell leading edge

ANGPTL3 GAS7 GRIA2 CIT

2.74e-03500254GO:0031252
GeneOntologyCellularComponentdendritic shaft

GRIA2 GRIA3

3.52e-0374252GO:0043198
GeneOntologyCellularComponentpresynaptic active zone membrane

GRIA2 GRIA3

3.90e-0378252GO:0048787
GeneOntologyCellularComponentreceptor complex

GRIA2 GRIA3 LRP1B NOTCH3

4.70e-03581254GO:0043235
GeneOntologyCellularComponentterminal bouton

GRIA2 GRIA3

5.85e-0396252GO:0043195
GeneOntologyCellularComponentendoplasmic reticulum lumen

GANAB WNT3 WNT6

7.05e-03332253GO:0005788
GeneOntologyCellularComponentexcitatory synapse

GRIA2 GRIA3

7.21e-03107252GO:0060076
GeneOntologyCellularComponentGolgi lumen

WNT3 WNT6

7.47e-03109252GO:0005796
DomainWnt

WNT3 WNT6 WNT16

2.02e-0619253IPR005817
DomainWNT1

WNT3 WNT6 WNT16

2.02e-0619253SM00097
DomainWnt_CS

WNT3 WNT6 WNT16

2.02e-0619253IPR018161
Domainwnt

WNT3 WNT6 WNT16

2.02e-0619253PF00110
DomainWNT1

WNT3 WNT6 WNT16

2.02e-0619253PS00246
DomainIontro_rcpt

GRIA2 GRIA3

2.60e-0418252IPR001320
DomainLig_chan

GRIA2 GRIA3

2.60e-0418252PF00060
DomainLig_chan-Glu_bd

GRIA2 GRIA3

2.60e-0418252PF10613
DomainPBPe

GRIA2 GRIA3

2.60e-0418252SM00079
DomainIono_rcpt_met

GRIA2 GRIA3

2.60e-0418252IPR001508
DomainGlu/Gly-bd

GRIA2 GRIA3

2.60e-0418252IPR019594
DomainLig_chan-Glu_bd

GRIA2 GRIA3

2.60e-0418252SM00918
DomainSRCR

SSC5D SSC4D

3.56e-0421252PF00530
DomainSR

SSC5D SSC4D

5.06e-0425252SM00202
Domain-

SSC5D SSC4D

5.06e-04252523.10.250.10
DomainSRCR_1

SSC5D SSC4D

5.48e-0426252PS00420
DomainSRCR-like_dom

SSC5D SSC4D

5.48e-0426252IPR017448
DomainSRCR_2

SSC5D SSC4D

5.48e-0426252PS50287
DomainSRCR

SSC5D SSC4D

5.92e-0427252IPR001190
DomainANF_receptor

GRIA2 GRIA3

1.11e-0337252PF01094
DomainANF_lig-bd_rcpt

GRIA2 GRIA3

1.11e-0337252IPR001828
DomainPeripla_BP_I

GRIA2 GRIA3

1.24e-0339252IPR028082
DomainGlycoside_hydrolase_SF

GBA3 GANAB

2.27e-0353252IPR017853
DomainEGF_extracell

LRP1B NOTCH3

2.90e-0360252IPR013111
DomainEGF_2

LRP1B NOTCH3

2.90e-0360252PF07974
DomainEGF_CA

LRP1B NOTCH3

5.87e-0386252PF07645
DomainEGF_Ca-bd_CS

LRP1B NOTCH3

7.41e-0397252IPR018097
DomainEGF_CA

LRP1B NOTCH3

7.71e-0399252PS01187
DomainASX_HYDROXYL

LRP1B NOTCH3

7.86e-03100252PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1B NOTCH3

8.79e-03106252IPR000152
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION

WNT3 WNT6 WNT16

3.15e-0619223M47836
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT3 WNT6 WNT16

7.42e-0625223MM14940
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT3 WNT6 WNT16

8.38e-0626223M27239
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR

WNT3 WNT6 WNT16

1.05e-0528223M47835
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT3 WNT6 WNT16

1.17e-0529223M47372
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT3 WNT6 WNT16

1.17e-0529223M47377
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

WNT3 WNT6 WNT16

2.28e-0536223M39699
PathwayKEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

WNT3 WNT6 WNT16

2.48e-0537223M47411
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

WNT3 WNT6 NOTCH3 WNT16

3.04e-05118224M39852
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

WNT3 WNT6 WNT16

4.19e-0544223MM15878
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

WNT3 WNT6 WNT16

4.49e-0545223M47412
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

WNT3 WNT6 WNT16

4.79e-0546223M47409
PathwayKEGG_BASAL_CELL_CARCINOMA

WNT3 WNT6 WNT16

8.21e-0555223M17807
PathwayWP_BREAST_CANCER_PATHWAY

WNT3 WNT6 NOTCH3 WNT16

8.60e-05154224M39739
PathwayKEGG_HEDGEHOG_SIGNALING_PATHWAY

WNT3 WNT6 WNT16

8.67e-0556223M1053
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

WNT3 WNT6 NOTCH3 WNT16

1.02e-04161224M39770
PathwayWP_WNT_SIGNALING

WNT3 WNT6 WNT16

1.12e-0461223MM15893
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

GRIA2 GRIA3

2.75e-0416222MM15048
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

WNT3 WNT6 WNT16

3.00e-0485223M48315
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

GRIA2 GRIA3

3.12e-0417222M5488
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

WNT3 WNT6 WNT16

3.43e-0489223M39563
PathwayWNT_SIGNALING

WNT3 WNT6 WNT16

3.43e-0489223M5493
PathwayWP_NRXN1_DELETION_SYNDROME

GRIA2 GRIA3

3.50e-0418222M48098
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

WNT3 WNT6 WNT16

4.03e-0494223M797
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

WNT3 WNT6 WNT16

4.56e-0498223M39731
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA2 GRIA3

4.80e-0421222M838
PathwayWP_PLEURAL_MESOTHELIOMA

ADAMTS1 CIT WNT3 WNT6 WNT16

4.86e-04439225M42563
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

WNT3 WNT6 WNT16

4.98e-04101223MM15829
PathwayKEGG_MELANOGENESIS

WNT3 WNT6 WNT16

4.98e-04101223M7761
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

WNT3 WNT6 WNT16

4.98e-04101223M39387
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

GRIA2 GRIA3

5.27e-0422222M39795
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA2 GRIA3

5.27e-0422222MM15104
PathwayWP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT

WNT3 WNT6 WNT16

6.39e-04110223M39492
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

MIB2 NOTCH3

6.82e-0425222M27879
PathwayWP_WNT_SIGNALING_WP428

WNT3 WNT6 WNT16

6.91e-04113223M39669
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

WNT3 WNT6 WNT16

7.46e-04116223MM15863
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

WNT3 WNT6 WNT16

7.65e-04117223M39530
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

GRIA2 GRIA3

9.20e-0429222MM15028
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

GRIA2 GRIA3

1.05e-0331222M7223
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

GRIA2 GRIA3

1.34e-0335222MM15109
PathwayKEGG_WNT_SIGNALING_PATHWAY

WNT3 WNT6 WNT16

1.60e-03151223M19428
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

GRIA2 GRIA3

1.84e-0341222M39655
PathwayREACTOME_SIGNALING_BY_NOTCH3

MIB2 NOTCH3

2.62e-0349222M618
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS1 NOTCH3

4.98e-0368222M27303
PathwayKEGG_LONG_TERM_DEPRESSION

GRIA2 GRIA3

5.27e-0370222M8232
PathwayREACTOME_SIGNALING_BY_WNT

WNT3 WNT6 WNT16

5.84e-03239223MM14756
PathwayWP_CANCER_PATHWAYS

WNT3 WNT6 NOTCH3 WNT16

7.22e-03507224M48302
PathwayWP_ALZHEIMERS_DISEASE

WNT3 WNT6 WNT16

7.45e-03261223M42565
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

GRIA2 GRIA3

9.32e-0394222M2843
PathwayREACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION

UBR2 UBA3 MIB2

1.08e-02299223MM15711
Pubmed

Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.

WNT3 WNT6 WNT16

8.12e-081226315778975
Pubmed

Wnt family proteins are secreted and associated with the cell surface.

WNT3 WNT6 WNT16

2.50e-07172638167409
Pubmed

Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis.

WNT3 WNT6 WNT16

3.57e-071926311520664
Pubmed

Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.

WNT3 WNT6 WNT16

4.89e-072126331914354
Pubmed

The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.

WNT3 WNT6 WNT16

4.89e-072126311914369
Pubmed

Involvement of GluR2 and GluR3 subunit C-termini in the trigeminal spinal subnucleus caudalis and C1-C2 neurons in trigeminal neuropathic pain.

GRIA2 GRIA3

5.37e-07226221215292
Pubmed

Involvement of AMPA receptor GluR2 and GluR3 trafficking in trigeminal spinal subnucleus caudalis and C1/C2 neurons in acute-facial inflammatory pain.

GRIA2 GRIA3

5.37e-07226222937151
Pubmed

Synaptic transmission and plasticity in the absence of AMPA glutamate receptor GluR2 and GluR3.

GRIA2 GRIA3

5.37e-07226212848940
Pubmed

Glutamatergic (N-methyl-D-aspartate receptor) hypofrontality in schizophrenia: too little juice or a miswired brain?

GRIA2 GRIA3

5.37e-07226219933774
Pubmed

GluR2-free alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors intensify demyelination in experimental autoimmune encephalomyelitis.

GRIA2 GRIA3

5.37e-07226217472701
Pubmed

Endocytosis and recycling of AMPA receptors lacking GluR2/3.

GRIA2 GRIA3

5.37e-07226218195348
Pubmed

Activation of beta-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration.

WNT3 WNT6 WNT16

5.66e-072226318991257
Pubmed

Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.

WNT3 WNT6 WNT16

6.50e-072326327362799
Pubmed

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.

WNT3 WNT6 WNT16

1.20e-062826320940229
Pubmed

Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.

WNT3 WNT6 WNT16

1.20e-062826324394376
Pubmed

Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.

WNT3 WNT6 WNT16

1.34e-062926322956684
Pubmed

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).

WNT3 WNT6 WNT16

1.34e-062926318364260
Pubmed

Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.

WNT3 WNT6 WNT16

1.49e-063026321936019
Pubmed

Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.

WNT3 WNT6 WNT16

1.49e-063026315880404
Pubmed

Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.

WNT3 WNT6 WNT16

1.49e-063026319282366
Pubmed

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.

WNT3 WNT6 WNT16

1.49e-063026336305473
Pubmed

NMDAR-dependent presynaptic homeostasis in adult hippocampus: Synapse growth and cross-modal inhibitory plasticity.

GRIA2 GRIA3

1.61e-06326236070750
Pubmed

An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain.

GRIA2 GRIA3

1.61e-06326232569783
Pubmed

Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex.

GRIA2 GRIA3

1.61e-06326236223737
Pubmed

Persistent synaptic scaling independent of AMPA receptor subunit composition.

GRIA2 GRIA3

1.61e-06326223864664
Pubmed

AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.

GRIA2 GRIA3

1.61e-06326234426577
Pubmed

AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy.

GRIA2 GRIA3

1.61e-06326215145077
Pubmed

Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain.

GRIA2 GRIA3

1.61e-06326228290985
Pubmed

Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain.

GRIA2 GRIA3

1.61e-06326226585043
Pubmed

Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors.

GRIA2 GRIA3

1.61e-06326214687553
Pubmed

Linking supply to demand: the neuronal monocarboxylate transporter MCT2 and the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid receptor GluR2/3 subunit are associated in a common trafficking process.

GRIA2 GRIA3

1.61e-06326219453627
Pubmed

Synaptic homeostasis requires the membrane-proximal carboxy tail of GluA2.

GRIA2 GRIA3

1.61e-06326229180434
Pubmed

Opposing gradients of ribbon size and AMPA receptor expression underlie sensitivity differences among cochlear-nerve/hair-cell synapses.

GRIA2 GRIA3

1.61e-06326221248103
Pubmed

GluA2 (GluR2) regulates metabotropic glutamate receptor-dependent long-term depression through N-cadherin-dependent and cofilin-mediated actin reorganization.

GRIA2 GRIA3

1.61e-06326221248105
Pubmed

Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage.

GRIA2 GRIA3

1.61e-06326215144856
Pubmed

The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn.

GRIA2 GRIA3

1.61e-0632629892356
Pubmed

Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.

GRIA2 GRIA3

1.61e-06326218163426
Pubmed

Neuronal enriched endosomal protein of 21 kDa colocalizes with glutamate receptor subunit GLUR2/3 at the postsynaptic membrane.

GRIA2 GRIA3

1.61e-06326219063943
Pubmed

Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach.

GRIA2 GRIA3

1.61e-06326219409270
Pubmed

Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase.

GRIA2 GRIA3

1.61e-06326212700243
Pubmed

MIB2 variants altering NOTCH signalling result in left ventricle hypertrabeculation/non-compaction and are associated with Ménétrier-like gastropathy.

MIB2 NOTCH3

1.61e-06326228013292
Pubmed

Synaptic targeting of AMPA receptors is regulated by a CaMKII site in the first intracellular loop of GluA1.

GRIA2 GRIA3

1.61e-06326221135237
Pubmed

Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors.

GRIA2 GRIA3

1.61e-06326223595422
Pubmed

Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP.

GRIA2 GRIA3

1.61e-0632629768844
Pubmed

Subunit-specific role for the amino-terminal domain of AMPA receptors in synaptic targeting.

GRIA2 GRIA3

1.61e-06326228630296
Pubmed

Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma.

WNT3 WNT16

1.61e-06326227630294
Pubmed

LTP requires a reserve pool of glutamate receptors independent of subunit type.

GRIA2 GRIA3

1.61e-06326223235828
Pubmed

WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.

WNT3 WNT6 WNT16

2.39e-063526330940800
Pubmed

Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.

WNT3 WNT6 WNT16

2.39e-063526323376422
Pubmed

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.

WNT3 WNT6 WNT16

2.39e-063526319185060
Pubmed

Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.

WNT3 WNT6 WNT16

2.39e-063526332907846
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

WNT3 WNT6 WNT16

2.83e-063726335831952
Pubmed

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

WNT3 WNT6 WNT16

2.83e-063726315342465
Pubmed

Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.

WNT3 WNT6 WNT16

2.83e-063726318800919
Pubmed

Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.

WNT3 WNT6 WNT16

3.07e-063826323190887
Pubmed

Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.

WNT3 WNT6 WNT16

3.07e-063826321041481
Pubmed

Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

GRIA2 GRIA3

3.22e-06426210027300
Pubmed

A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.

GRIA2 GRIA3

3.22e-06426210688364
Pubmed

Cortactin regulates endo-lysosomal sorting of AMPARs via direct interaction with GluA2 subunit.

GRIA2 GRIA3

3.22e-06426229515177
Pubmed

Chromosomal localization of human glutamate receptor genes.

GRIA2 GRIA3

3.22e-0642621319477
Pubmed

AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.

GRIA2 GRIA3

3.22e-06426212692557
Pubmed

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival.

GRIA2 GRIA3

3.22e-06426228608780
Pubmed

Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice.

GRIA2 GRIA3

3.22e-06426215619115
Pubmed

GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons.

GRIA2 GRIA3

3.22e-06426226932439
Pubmed

Salmonella regulation of intestinal stem cells through the Wnt/beta-catenin pathway.

WNT3 WNT6

3.22e-06426220083111
Pubmed

Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.

GRIA2 GRIA3

3.22e-06426212125045
Pubmed

AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.

GRIA2 GRIA3

3.22e-0642629221927
Pubmed

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

GRIA2 GRIA3

3.22e-06426225337787
Pubmed

Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.

GRIA2 GRIA3

3.22e-06426217828255
Pubmed

Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development.

GRIA2 GRIA3

3.22e-06426231231192
Pubmed

The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.

GRIA2 GRIA3

3.22e-06426224652293
Pubmed

Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.

GRIA2 GRIA3

3.22e-06426217409242
Pubmed

The cell-autonomous role of excitatory synaptic transmission in the regulation of neuronal structure and function.

GRIA2 GRIA3

3.22e-06426223664612
Pubmed

The Role of AMPARs in the Maturation and Integration of Caudal Ganglionic Eminence-Derived Interneurons into Developing Hippocampal Microcircuits.

GRIA2 GRIA3

3.22e-06426230931998
Pubmed

AMPA receptor deletion in developing MGE-derived hippocampal interneurons causes a redistribution of excitatory synapses and attenuates postnatal network oscillatory activity.

GRIA2 GRIA3

3.22e-06426231992779
Pubmed

LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes.

GRIA2 GRIA3

3.22e-06426229581259
Pubmed

AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62.

GRIA2 GRIA3

3.22e-06426219004011
Pubmed

Distribution of alpha-amino-3-hydroxy-5-methyl-4 isoazolepropionic acid and N-methyl-D-aspartate receptor subunits in the vestibular and spiral ganglia of the mouse during early development.

GRIA2 GRIA3

3.22e-06426212414093
Pubmed

Effects of mGlu2 or mGlu3 receptor deletions on mGlu2/3 receptor agonist (LY354740)-induced brain c-Fos expression: specific roles for mGlu2 in the amygdala and subcortical nuclei, and mGlu3 in the hippocampus.

GRIA2 GRIA3

3.22e-06426216733060
Pubmed

Regulated expression of Wnt family members during neuroectodermal differentiation of P19 embryonal carcinoma cells: overexpression of Wnt-1 perturbs normal differentiation-specific properties.

WNT3 WNT6

3.22e-0642627958454
Pubmed

Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.

GRIA2 GRIA3

3.22e-06426214561864
Pubmed

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.

GRIA2 GRIA3

3.22e-06426232831170
Pubmed

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

GRIA2 GRIA3

3.22e-0642629648857
Pubmed

Use of MGLUR2 and MGLUR3 knockout mice to explore in vivo receptor specificity of the MGLUR2/3 selective antagonist LY341495.

GRIA2 GRIA3

3.22e-06426219477188
Pubmed

Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.

WNT3 WNT6 WNT16

3.33e-063926324586192
Pubmed

Gpr177 regulates pulmonary vasculature development.

WNT3 WNT6 WNT16

4.81e-064426323884445
Pubmed

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.

GRIA2 GRIA3

5.37e-0652629482932
Pubmed

Phase Separation-Mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission.

GRIA2 GRIA3

5.37e-06526231492534
Pubmed

The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking.

GRIA2 GRIA3

5.37e-06526222445342
Pubmed

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

GRIA2 GRIA3

5.37e-0652621717158
Pubmed

Oligodendrocytes as regulators of neuronal networks during early postnatal development.

GRIA2 GRIA3

5.37e-06526221589880
Pubmed

Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF.

GRIA2 GRIA3

5.37e-06526215797551
Pubmed

Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

GRIA2 GRIA3

5.37e-06526216129400
Pubmed

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.

WNT3 WNT6 WNT16

5.88e-064726316678101
Pubmed

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

WNT3 WNT6 WNT16

5.88e-064726328813421
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

WNT3 WNT6 WNT16

5.88e-064726333141892
Pubmed

Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.

WNT3 WNT6 WNT16

5.88e-064726318351675
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

WNT3 WNT6 WNT16

6.68e-064926319562671
Pubmed

WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth.

WNT3 WNT6 WNT16

7.10e-065026318351662
Pubmed

Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission.

GRIA2 GRIA3

8.05e-06626216990550
GeneFamilyWnt family|Endogenous ligands

WNT3 WNT6 WNT16

9.43e-0719193360
GeneFamilyGlutamate ionotropic receptor AMPA type subunits

GRIA2 GRIA3

6.27e-0641921200
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SSC5D SSC4D

3.62e-04271921253
GeneFamilyAnkyrin repeat domain containing

MIB2 NOTCH3

2.63e-02242192403
CoexpressionBENPORATH_SUZ12_TARGETS

GAS7 GRIA2 WNT3 WNT6 ACSS1 WNT16 CLEC4G

4.99e-051035267M9898
CoexpressionNABA_MATRISOME_ASSOCIATED

ANGPTL3 ADAMTS1 WNT3 WNT6 WNT16 CLEC4G

6.94e-05738266MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

ANGPTL3 ADAMTS1 WNT3 WNT6 WNT16 CLEC4G

7.65e-05751266M5885
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D VMO1 WNT6 WNT16

8.36e-0712626483f3540683b3b175b10af059ab8898c46eaccc13
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D VMO1 WNT6 WNT16

8.36e-07126264f20424f9baf3c4059cd6b701761e7595400fc47c
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D VMO1 WNT6 WNT16

8.36e-071262646d5075d659dac7b96e6857f8485a7d2c4105d685
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D VMO1 WNT6 WNT16

8.36e-07126264fd0001a0f3a0a4421f96fd21813c21cf6f01d40e
ToppCellP03-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GAS7 WNT3 WNT6 WNT16

3.77e-061842648880ff36c243cc60a524d74934d000aef26a70ac
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIA3 SSC5D ADAMTS1 NOTCH3

4.46e-06192264992d08092edbc68c47b945deb8708379738c239a
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GRIA3 LRP1B CLEC4G

7.28e-05140263c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VMO1 NOTCH3 CLEC4G

9.84e-051552638dab23aad905cc35a35643baa0554acb3f6fe6c8
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VMO1 NOTCH3 CLEC4G

9.84e-0515526342533beaded07068f00540de704de07e4f19abcf
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRIA2 GRIA3 LRP1B

9.84e-0515526377fdae85d36efb776db977eb424b32487ef222e4
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SSC5D VMO1 WNT6

1.06e-04159263cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-|GI_small-bowel / Manually curated celltypes from each tissue

GAS7 ADAMTS1 WNT6

1.16e-0416426336e64e4f717dd59b352c20ff9742ca1e232342bb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D WNT6 ACSS1

1.23e-041672632184c2760b6142e62124a2454a552723e20d4f61
ToppCelldroplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA3 NOTCH3 CLEC4G

1.32e-041712634e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SSC4D LRP1B WNT6

1.36e-04173263b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK|GI_small-bowel / Manually curated celltypes from each tissue

GAS7 ADAMTS1 WNT6

1.38e-0417426309b216f07cffd3ea2149ea95ffb5cd7219b3a98c
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPN12 MIB2 ADAMTS1

1.41e-04175263e219b61d6bc078d44ea7d06191d3462654d857a1
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPN12 MIB2 ADAMTS1

1.41e-04175263bd16c80418bf71127e6f1e50edf83967c9218b42
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CAPN12 MIB2 ADAMTS1

1.41e-041752630ed053aa8353c72ff37fee830672704a3ddc7d85
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ADAMTS1 LRP1B NOTCH3

1.41e-04175263fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CAPN12 MIB2 ADAMTS1

1.41e-041752630124a3c4696b39cee8b566e94603d1d3d128bfa5
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ADAMTS1 WNT6 NOTCH3

1.43e-041762632015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA2 GRIA3 CIT

1.46e-041772631dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA2 GRIA3 CIT

1.46e-04177263426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 WNT6 NOTCH3

1.46e-04177263452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL3 GAS7 WNT6

1.48e-041782633e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

GRIA2 ADAMTS1 NOTCH3

1.51e-04179263111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VMO1 CLEC4G NAIP

1.53e-041802637af90f0e7ca001bf1fe5c860ee54c4cc8eb483bf
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS1 WNT6 NOTCH3

1.56e-0418126333cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS1 WNT6 NOTCH3

1.58e-04182263e67f3234165199085c793915ebb1f9bbd845e933
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VMO1 CLEC4G NAIP

1.61e-0418326392d5a61b57851090eba558f19e2a7010043eff81
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIA2 WNT3 WNT16

1.63e-041842633e5c68a99c10eb1ddc1048bea4aa9f6b8e2746ff
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 WNT6 NOTCH3

1.63e-04184263603faafb7b289a3c0242c84fc800c050c8a092ea
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIA2 WNT3 WNT16

1.63e-041842631e2f0cec50475a1cf2973a5082826bbc60fc9a68
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 WNT6 NOTCH3

1.63e-04184263c350504bfe0ec31cd2fc2199de9b5fff151a8c5e
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GAS7 SSC5D ADAMTS1

1.66e-04185263d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D175|Adult / Lineage, Cell type, age group and donor

GAS7 CLEC4G NAIP

1.66e-04185263ab5704b96f1d368911308797d10c7c52766ab134
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA2 GRIA3 CIT

1.69e-0418626316092819e9148dfe64f07c737652b6e533e699f7
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA2 GRIA3 CIT

1.69e-041862634bb54043f944a979db91bde9a86dd66f498c7658
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CAPN12 MIB2 ADAMTS1

1.69e-04186263165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTS1 LRP1B CIT

1.71e-041872632ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCellMonocytes-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

GAS7 CLEC4G NAIP

1.74e-04188263756375cf9c9cccc4fb4a7f5e4756fa3fc36a7892
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT3 WNT6 WNT16

1.74e-041882638cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT3 WNT6 WNT16

1.77e-041892631cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCellfacs-Skin-nan-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT3 WNT6 WNT16

1.77e-041892636c71e81373cb7822de23c193a6350b6df9f567bc
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SSC5D ADAMTS1 NOTCH3

1.77e-041892637ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIA3 SSC5D NOTCH3

1.77e-0418926345e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SSC5D ADAMTS1 LRP1B

1.79e-04190263938d1f66094b1c94606e0d40213a39e5112f3322
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIA2 ADAMTS1 NOTCH3

1.85e-04192263b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAS7 VMO1 NAIP

1.85e-0419226322f335e6e75a694cdccafe189b5ee7815ef28c03
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIA2 ADAMTS1 NOTCH3

1.85e-04192263bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SSC5D ADAMTS1 NOTCH3

1.88e-04193263000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)|Adult / Lineage, Cell type, age group and donor

GAS7 CLEC4G NAIP

1.88e-0419326331c0978ba78c9516d498aec0798902e57555e557
ToppCellICU-SEP-Lymphocyte-T_NK-NK|ICU-SEP / Disease, Lineage and Cell Type

CAPN12 MIB2 ADAMTS1

1.88e-04193263f110f86db305e41639087f5b1a2dff103c07adf0
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA3 SSC5D ADAMTS1

1.91e-0419426391205b22650e7ecdb72bb59348ce2530b76c532c
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS7 CLEC4G NAIP

1.91e-041942637b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA3 SSC5D ADAMTS1

1.91e-041942638fae8061b350336299aa81f378e07deadbd55123
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA3 SSC5D ADAMTS1

1.91e-041942634d7d24390fdb379f943ddcc70a63f23955e10163
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA3 SSC5D ADAMTS1

1.91e-041942636e12a7da35be4c0ecf998ef94b8989b89d74b200
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA3 SSC5D ADAMTS1

1.91e-04194263c52f10140c66e8c0566421c3d535d5d92bf595e1
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS7 CLEC4G NAIP

1.91e-04194263435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS7 CLEC4G NAIP

1.91e-0419426348c37251518f96524807b5bd1bbc2820637666ad
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VMO1 CLEC4G NAIP

1.91e-04194263ad72be9f6871b334e1f477d868c15e7792fadea5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIA2 SSC5D ADAMTS1

1.94e-041952638a04f0e92d10a368ccda5f566ae67ef51f1d34a9
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTS1 LRP1B CIT

1.97e-0419626304f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GAS7 GRIA2 WNT6

1.97e-04196263b6226163d9fc93ecfff2115bb74408303a000490
ToppCell(7)_Macrophage|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

VMO1 NOTCH3 NAIP

1.97e-04196263f1c822860d2a0bae84b0263b0151185756423e0f
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA3 SSC5D ADAMTS1

2.00e-0419726316758f181ef07c60aee63072e1da9572c5c85414
ToppCellmedial-2-Hematologic-Classical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GAS7 CLEC4G NAIP

2.00e-04197263fbff79d6ece1605126ae0caa0c71253ea557779c
ToppCellmedial-Hematologic-Classical_Monocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GAS7 CLEC4G NAIP

2.00e-041972633960eac4b6753e3294e13901f6ea13d894275c8d
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS1 WNT6 NOTCH3

2.00e-04197263bc6c530330907a5ec823cc243c8e9c9e340cfb9c
ToppCellVE-NK|VE / Condition, Cell_class and T cell subcluster

CAPN12 GAS7 ADAMTS1

2.00e-04197263cae6ff8763501e7a5897b50188ac2640d65a47c0
ToppCelldistal-mesenchymal-Lipofibroblast-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GRIA2 ADAMTS1 WNT6

2.00e-04197263865010edcd7e3f79f505fcef7b33882095994aa8
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS7 SSC5D ADAMTS1

2.00e-04197263c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCelldistal-mesenchymal-Lipofibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GRIA2 ADAMTS1 WNT6

2.00e-04197263ceb83bdef16b58ee16193413bfb006f7715728b2
ToppCellVE-NK-|VE / Condition, Cell_class and T cell subcluster

CAPN12 GAS7 ADAMTS1

2.00e-04197263ee89b8521fb4faaed9e4d39f7171e45eccf38b00
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GAS7 WNT6 NAIP

2.00e-041972637870c0651caefb0ed13d9f9dab43b5f24d6a9efc
ToppCellmedial-Hematologic-Classical_Monocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GAS7 CLEC4G NAIP

2.00e-04197263ae2b51d4e91126ee0a0f69c040297c2a78ce27dd
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GAS7 GRIA2 WNT6

2.00e-04197263e239caae24f40564a24ad909754f5436f767ccdb
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAS7 VMO1 NAIP

2.00e-04197263e698a0bbb20bd4868ff4348f2ac9f609942b55fa
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS1 WNT6 NOTCH3

2.00e-0419726377fe092aae8f05fe137680506892d2f61071d6ea
ToppCellmedial-2-Hematologic-Intermediate_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GAS7 CLEC4G NAIP

2.03e-04198263432a26ace5b486695c9a933c0d44b73305b01ded
ToppCellmedial-Hematologic-Intermediate_Monocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GAS7 CLEC4G NAIP

2.03e-04198263dbd7869483c5a67944cb94ced0ee2c7b999adc2e
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GRIA3 SSC5D ADAMTS1

2.03e-04198263e9f434bfd072e590fe44d518057ee5aa653038f3
ToppCellmedial-Hematologic-Intermediate_Monocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GAS7 CLEC4G NAIP

2.03e-041982638f64bb5cd8c3e2d5ef651821b0d59f67d1ca1a12
ToppCellsevere-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANGPTL3 GAS7 NAIP

2.03e-04198263d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SSC5D ADAMTS1 LRP1B

2.06e-04199263a207b4891881149d4c50721310690fd794157723
ToppCellTracheal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 WNT6 NOTCH3

2.06e-04199263cefc3b50f65e95da850e4720c7b44bf584073491
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SSC5D ADAMTS1 NOTCH3

2.06e-04199263aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac|lymph-node_spleen / Manually curated celltypes from each tissue

VMO1 NOTCH3 NAIP

2.06e-04199263c051cc3e42cfa2ec09fd8dae1172af350bb2dfcb
ToppCellBronchus_Control_(B.)-Immune-TX-MoAM-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

GAS7 CLEC4G NAIP

2.06e-04199263fb63885273d906a85fef178d859d20a311eb8a72
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GRIA3 SSC5D ADAMTS1

2.06e-0419926338cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

GAS7 SSC5D VMO1

2.06e-04199263facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Erythrophagocytic_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

VMO1 NOTCH3 NAIP

2.06e-0419926378db2e3b85356ed2f08794e5a97c16a220f8a076
ToppCellTracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 WNT6 NOTCH3

2.06e-04199263aaa460c389cd6d38a13ba1a446f91a94f9573ad8
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

GAS7 SSC5D VMO1

2.06e-04199263dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCellTransverse-Macrophage-Macrophage|Transverse / Region, Cell class and subclass

GAS7 VMO1 NAIP

2.09e-0420026317548806ba38008050244151d1216c69ef8a8310
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

GRIA3 SSC5D ADAMTS1

2.09e-0420026308bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SSC5D ADAMTS1 NOTCH3

2.09e-0420026367dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellTransverse-(6)_Macrophage|Transverse / shred on region, Cell_type, and subtype

GAS7 VMO1 NAIP

2.09e-04200263b28350de555fa756d2631f004f71d5ac69b1affe
DrugAniracetam

GRIA2 GRIA3

7.51e-064262DB04599
Drug3-pyridazinol 1-oxide

GRIA2 GRIA3

7.51e-064262CID000574311
Drugpropionate

GRIA2 GRIA3 CPOX CIT ACSS1

1.05e-05262265CID000001032
DrugGAMs

GRIA2 GRIA3 ADAMTS1

1.09e-0538263CID000002935
Drug3,4-dioctylphthalic acid

GRIA2 GRIA3 CIT ACSS1

1.22e-05126264CID005743034
DrugAC1L1YEG

GRIA2 GRIA3

1.25e-055262CID000063114
DrugChicago acid

GRIA2 GRIA3

1.25e-055262CID000065740
Drugirampanel

GRIA2 GRIA3

1.25e-055262CID003038472
DrugCHEBI:570577

GRIA2 GRIA3

1.25e-055262CID011334126
Drugbeta-N-oxalylaminoalanine

GRIA2 GRIA3

1.25e-055262CID000107978
DrugLY395153

GRIA2 GRIA3

1.25e-055262CID000656707
Drug5-h PCA

GRIA2 GRIA3

1.25e-055262CID000129091
Drug1-BCP

GRIA2 GRIA3

1.25e-055262CID000001370
DrugSB216763

WNT3 WNT6 WNT16

1.27e-0540263CID000176158
DrugAC1NNRU4

GRIA2 GRIA3 CIT

1.37e-0541263CID005126051
Drug2cmo

GRIA2 GRIA3

1.88e-056262CID006914597
DrugYM928

GRIA2 GRIA3

1.88e-056262CID006918393
Drug4,6-dichloroindole-2-carboxylic acid

GRIA2 GRIA3

2.62e-057262CID000127988
Drugthio-ATPA

GRIA2 GRIA3

2.62e-057262CID005289517
Drugnickel

GBA3 GRIA2 GRIA3 ADAMTS1 CIT NOTCH3

3.01e-05552266CID000000934
DrugMDL 28170

CAPN12 GRIA2 GRIA3

3.15e-0554263CID000072430
Drug2,3-PDCA

GRIA2 GRIA3

3.50e-058262CID000127037
Drug1-hydroxyimidazole

GRIA2 GRIA3

3.50e-058262CID003614351
Drughomoibotenic acid

GRIA2 GRIA3

3.50e-058262CID000194385
Drug1-hydroxypyrazole

GRIA2 GRIA3

3.50e-058262CID003016733
DrugLy294486

GRIA2 GRIA3

4.49e-059262CID005311255
Drug1m5b

GRIA2 GRIA3

4.49e-059262CID000447081
Drugisothiazol-3-one

GRIA2 GRIA3

4.49e-059262CID000096917
Drugpyrrolidine-2,4-dicarboxylate

GRIA2 GRIA3 CIT

4.55e-0561263CID000003868
DrugBenzoates

GRIA2 GRIA3

5.61e-0510262ctd:D001565
DrugJ-ST

GRIA2 GRIA3

6.85e-0511262CID005288655
Drug0-ol

GRIA2 GRIA3

6.85e-0511262CID000069892
Drugsym 2206

GRIA2 GRIA3

6.85e-0511262CID005039877
DrugYM872

GRIA2 GRIA3

6.85e-0511262CID000148200
DrugCefixime [79350-37-1]; Up 200; 8.8uM; PC3; HT_HG-U133A

GAS7 WNT3 WNT6 WNT16

6.86e-051962644567_UP
DrugBephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; MCF7; HT_HG-U133A

GAS7 GRIA3 LRP1B WNT16

7.14e-051982645628_UP
DrugCyproterone acetate [427-51-0]; Up 200; 9.6uM; PC3; HT_HG-U133A

GAS7 WNT3 WNT16 SERGEF

7.14e-051982644470_UP
Drugifenprodil

GRIA2 GRIA3 CPOX

7.18e-0571263CID000003689
DrugParomomycin sulfate [1263-89-4]; Up 200; 5.6uM; PC3; HT_HG-U133A

GAS7 GRIA3 NOTCH3 SERGEF

7.28e-051992644595_UP
DrugC-X6

GRIA2 GRIA3

8.22e-0512262CID005288002
DrugAtpa

GRIA2 GRIA3

8.22e-0512262CID000002252
Drug1NaPP1

GRIA2 GRIA3

8.22e-0512262CID000004877
Drugbenzyladenine

VMO1 CIT WNT16

9.14e-0577263CID000062389
DrugNaspm

GRIA2 GRIA3

9.71e-0513262CID000129695
Drugquinoxaline-2,3-dione

GRIA2 GRIA3

1.13e-0414262CID011469229
Drugestradiol-2,3-quinone

GRIA2 GRIA3 ADAMTS1

1.23e-0485263CID000066393
DrugDEHP

GRIA2 GRIA3 CIT

1.23e-0485263CID000008343
DrugNSC759587

GAS7 GRIA2 GRIA3 SSC4D NAIP

1.29e-04444265CID000003816
Drugthiokynurenic acid

GRIA2 GRIA3

1.30e-0415262CID003035667
DrugLY233536

GRIA2 GRIA3

1.49e-0416262CID000126239
Drugdecahydroisoquinoline

GRIA2 GRIA3

1.49e-0416262CID000097812
DrugPPNDS

GRIA2 GRIA3

1.69e-0417262CID005961627
Drug7-Cl-Thio-Kyna

GRIA2 GRIA3

1.69e-0417262CID003035668
DrugMNQX

GRIA2 GRIA3

1.90e-0418262CID000130818
DrugLY382884

GRIA2 GRIA3

2.12e-0419262CID000656723
DrugIDRA 21

GRIA2 GRIA3

2.35e-0420262CID000003688
DrugAC1L1B62

GRIA2 GRIA3

2.60e-0421262CID000001299
DrugFe-mo-s Cluster

GRIA2 GRIA3

2.86e-0422262CID000445682
Druganisamide

GRIA2 GRIA3

2.86e-0422262CID000075540
DrugNS 102

GRIA2 GRIA3

2.86e-0422262CID005282252
DrugCX516

GRIA2 GRIA3

2.86e-0422262CID000148184
Drugpentanol

GBA3 GRIA3

3.13e-0423262CID000006276
DrugMK-801

GRIA2 GRIA3 CPOX CIT

3.34e-04296264CID000001207
DrugCGP 39653

GRIA2 GRIA3

3.41e-0424262CID006437837
DrugpD 8

GRIA2 GRIA3

3.41e-0424262CID000656948
Drugmetsulfuron-methyl

GRIA2 GRIA3 CPOX

3.65e-04123263CID000052999
DrugNs102

GRIA2 GRIA3

3.70e-0425262CID005311098
Drug1-piperidinocyclohexanecarbonitrile

GBA3 NOTCH3

3.70e-0425262CID000062529
DrugAC1NUW3V

GRIA2 GRIA3

5.00e-0429262CID005462126
Druglinalool

GBA3 CIT

5.00e-0429262CID000006549
Drugmonatepil

SSC4D LRP1B

5.00e-0429262CID000060810
Drugrufinamide

GRIA2 GRIA3

5.00e-0429262CID000129228
DrugLY293558

GRIA2 GRIA3

5.35e-0430262CID000127894
DrugAC1L32TU

GRIA2 GRIA3

5.35e-0430262CID000107831
Drugmagnesium

GBA3 GRIA2 GRIA3 ADAMTS1 ACSS1 NOTCH3 SERGEF

5.50e-041325267CID000000888
DrugLY 171555

GRIA2 GRIA3 CIT

5.56e-04142263CID000001257
Drug4-methylglutamic acid

GRIA2 GRIA3

5.71e-0431262CID000005365
DrugKW-6002

GRIA2 GRIA3

6.09e-0432262CID005311037
Drugwillardine

GRIA2 GRIA3

6.09e-0432262CID000005123
Drugalpha-methyl-4-carboxyphenylglycine

GRIA2 GRIA3

6.09e-0432262CID000001222
Drug6,7-dinitroquinoxaline

GRIA2 GRIA3

6.48e-0433262CID002724608
DrugD-CPPene

GRIA2 GRIA3

6.88e-0434262CID006435801
Drugkainite

GRIA2 GRIA3

7.29e-0435262CID000164810
DrugTe-6

WNT3 WNT6

7.29e-0435262CID000198470
DrugPhTX-343

GRIA2 GRIA3

7.71e-0436262CID000159548
DrugDB07831

GBA3 GRIA2

7.71e-0436262CID010477723
DrugC6H12NO5P

GRIA2 GRIA3

7.71e-0436262CID000104962
DrugR,S)-AMPA

GRIA2 GRIA3

7.71e-0436262CID000001221
Drug4-methylumbelliferyl-beta-D-glucopyranoside

GBA3 GANAB

8.15e-0437262CID000087330
Druggamma-Glu-Gly

GRIA2 GRIA3

8.15e-0437262CID000100099
Drug8-cyclopentyltheophylline

CPOX CIT

8.60e-0438262CID000001917
DrugNivalenol hydrate

CIT CLEC4G

8.60e-0438262CID000031829
DrugL-BMAA

GRIA2 GRIA3

8.60e-0438262CID000028558
Drugpentane

ADAMTS1 CIT

8.60e-0438262CID000008003
DrugCGS 19755

GRIA2 GRIA3

8.60e-0438262CID000068736
DrugDETC-MeSO

GRIA2 GRIA3

9.05e-0439262CID003035711
DrugHA-966

GRIA2 GRIA3

9.05e-0439262CID000001232
DrugL000369

GRIA2 GRIA3

1.00e-0341262CID003931705
Drugadamantane

GRIA2 GRIA3

1.00e-0341262CID000009238
DrugSKF 81297

GRIA2 GRIA3

1.05e-0342262CID000001218
Diseasecortisol measurement, response to corticosteroid, response to synacthen

GBA3 LRP1B

5.79e-0513262EFO_0005843, EFO_0009175, GO_0031960
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA2 GRIA3

8.89e-0516262DOID:331 (implicated_via_orthology)
Diseaseneurodegenerative disease (implicated_via_orthology)

UBR2 GRIA2 GRIA3

2.78e-04145263DOID:1289 (implicated_via_orthology)
DiseaseLiver carcinoma

GBA3 ADAMTS1 NOTCH3 CLEC4G

9.54e-04507264C2239176
Diseaseschizophrenia, intelligence, self reported educational attainment

GBA3 GAS7 LRP1B

3.40e-03346263EFO_0004337, EFO_0004784, MONDO_0005090
Disease3-hydroxypropylmercapturic acid measurement

GAS7 LINC02901 LRP1B

3.57e-03352263EFO_0007014
Diseasebrain ischemia (biomarker_via_orthology)

ADAMTS1 NAIP

3.64e-03102262DOID:2316 (biomarker_via_orthology)
Diseasealcohol consumption measurement

CAPN12 CIT WNT3 ACSS1 SERGEF

4.12e-031242265EFO_0007878
Diseaseceliac disease

LINC02901 WNT3

5.50e-03126262EFO_0001060
DiseasePapillary Renal Cell Carcinoma

VMO1 LRP1B

5.67e-03128262C1306837
DiseaseRenal Cell Carcinoma

VMO1 LRP1B

5.67e-03128262C0007134
Diseasemood instability measurement

LRP1B WNT3

5.67e-03128262EFO_0008475
DiseaseSarcomatoid Renal Cell Carcinoma

VMO1 LRP1B

5.67e-03128262C1266043
DiseaseChromophobe Renal Cell Carcinoma

VMO1 LRP1B

5.67e-03128262C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

VMO1 LRP1B

5.67e-03128262C1266044

Protein segments in the cluster

PeptideGeneStartEntry
GGCLGNWEEGDDPWK

NAIP

201

Q13075
WDCDFSTGKIGWFLG

ACSS1

91

Q9NUB1
EGYSGGWWWHDECGE

ANGPTL3

396

Q9Y5C1
GKGTYGLDCDWWSVG

CIT

276

O14578
FPWADGTSCGEGKWC

ADAMTS1

526

Q9UHI8
PFWWKCDTVDDCGDG

LRP1B

3331

Q9NZR2
EAGVWCWDRGGWDGS

LINC02901

131

Q4VX62
KWWYDKGECGSGGGD

GRIA2

786

P42262
NKWWYDKGECGSGGG

GRIA3

796

P42263
GWDGGDCSLSVGDPW

NOTCH3

1411

Q9UM47
DDEDEEGPWGGWGAA

CAPN12

396

Q6ZSI9
GWDADGKGPCVWDTF

GBA3

21

Q9H227
VEEADGNKQWWFGGG

CPOX

266

P36551
GPDWEWGSQDGGEGK

MIB2

166

Q96AX9
WGWNEHGMCGDGTEA

SERGEF

356

Q9UGK8
DGGWWEGEKEDGLRG

GAS7

36

O60861
KTRDGSDYEGWCWPG

GANAB

491

Q14697
GLSWGDFGDWSDHCP

VMO1

156

Q7Z5L0
WHGGRWGTVCDDGWD

SSC5D

36

A1L4H1
GLWNDAPCDSEKDGW

CLEC4G

271

Q6UXB4
GGCGDTGDWEGRWNH

UBA3

26

Q8TBC4
HAGGWGTVCDDDWDF

SSC4D

361

Q8WTU2
EGWKWGGCSEDADFG

WNT3

151

P56703
PEGSAAWEWGGCGDD

WNT6

161

Q9Y6F9
AWEWGGCGDDVDFGD

WNT6

166

Q9Y6F9
GGSASEGWHWGGCSD

WNT16

156

Q9UBV4
GGFCDCGDTEAWKEG

UBR2

146

Q8IWV8